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$255+ Cheap flights from Portland, ME to Knoxville (PWM - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — TYS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Portland to Knoxville McGhee Tyson are usually found in December or November, booked 63 days in advance, depart on a Saturday or Wednesday and return on a Wednesday

Cheap flight deals from Portland to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$259
(Delta)

One-way from

$255
(Delta)

Popular in

May

Cheapest in

December

Average price

$373
From Portland to Knoxville McGhee Tyson
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One-way flight from Portland to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 16% potential increase in price ($72 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Portland to Knoxville

Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/75:53 amPWM - TYS
1 stop4h 14mAmerican Airlines
Tue 10/1410:59 amTYS - PWM
1 stop4h 06mAmerican Airlines
Deal found 6/11$259
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/75:40 amPWM - TYS
1 stop5h 25mDelta
Tue 10/145:30 amTYS - PWM
2 stops8h 51mDelta
Deal found 6/10$264
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/294:56 pmPWM - TYS
1 stop5h 40mUnited Airlines
Sun 8/317:00 amTYS - PWM
2 stops7h 25mUnited Airlines
Deal found 6/10$277
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/116:05 pmPWM - TYS
1 stop23h 54mMultiple Airlines
Fri 8/156:00 amTYS - PWM
1 stop11h 25mMultiple Airlines
Deal found 6/10$415

Cheapflights Fare Finder

Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Fly from

Portland

Fly to

Knoxville

Route

Depart

Return

Price

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Sat 8/16

6:00 am-10:27 am

1 stop4h 27m

Knoxville McGhee Tyson

Mon 8/18

7:50 am-12:08 pm

1 stop4h 18m

$259

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 9/4

1:09 pm-7:46 pm

2 stops6h 37m

Knoxville McGhee Tyson

Sun 9/7

1:03 pm-8:19 pm

1 stop7h 16m

$264

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Fri 8/29

4:56 pm-10:36 pm

1 stop5h 40m

Knoxville McGhee Tyson

Sun 8/31

7:00 am-2:25 pm

2 stops7h 25m

$277

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Mon 9/8

9:46 am-10:34 pm

1 stop12h 48m

Knoxville McGhee Tyson

Fri 9/12

1:22 pm-2:36 pm

1 stop25h 14m

$394

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Tue 7/8

6:05 am-10:46 am

1 stop4h 41m

$255

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Tue 7/8

1:50 pm-8:58 pm

2 stops31h 08m

$258

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Fri 9/5

5:10 pm-11:03 pm

1 stop5h 53m

$269

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Fri 8/1

5:35 am-10:27 am

1 stop4h 52m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland, Maine to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Knoxville. Price data was last updated on June 9, 2025.

The best time to book flights from Portland, Maine to Knoxville is 63 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland, Maine to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Knoxville (average of $296). Flying from Portland, Maine to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to TYS?

Find hourly flight availability from Portland to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

It’s optimal to fly from Portland, Maine to Knoxville at noon. By choosing this option you can save up to 10% on the cost of your flight, compared to a flight in the morning.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Portland to Knoxville have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Portland, Maine to Knoxville round-trip?

    Cheapflights users have booked flights from Portland, Maine to Knoxville round-trip from $259. Other airlines that can offer you cheap pricing are American Airlines, from $264, and United Airlines, from $277. You may be able to fly from Portland, Maine to Knoxville for 31% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Portland, Maine to Knoxville one-way?

    $255 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $269 and $304, respectively.

  • Can I find deals for flights from Portland to Knoxville that include hotel bookings?

    Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.

  • Can I find deals for business class flights from Portland to Knoxville?

    Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Knoxville (average of $296). Flying from Portland, Maine to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from Portland to Knoxville

Discover the top 3 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$213Average$349FlexibilityNo cancel feeOn-time71%
DeltaCheapest$225Average$398FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$363FlexibilityNo cancel feeOn-time69%

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