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Knoxville

$110+ Cheap flights from Orange County to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — TYS
Oct 19 — Oct 261
Sun 10/19
Sun 10/26
1 adult, Economy
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Cheap flight deals from Orange County to Knoxville

Keep the following information in mind while searching for Orange County to Knoxville flight deals. Data was last updated September 19, 2025.

Round-trip from

$289
(Delta)

One-way from

$110
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$481
From Orange County to Knoxville McGhee Tyson
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One-way flight from Orange County to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 15% potential increase in price ($100 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Orange County to Knoxville

Cheapest flights from Orange County to Knoxville
Explore the most affordable flight options available from Orange County to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/152:20 pmSNA - TYS
1 stop20h 24mMultiple Airlines
Thu 11/206:30 amTYS - SNA
1 stop7h 49mMultiple Airlines
Deal found 9/16$258
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/112:58 pmSNA - TYS
1 stop27h 52mFrontier
Sun 10/55:08 pmTYS - SNA
1 stop20h 59mFrontier
Deal found 9/16$277
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/111:48 amSNA - TYS
1 stop6h 25mDelta
Tue 11/43:59 pmTYS - SNA
1 stop9h 29mDelta
Deal found 9/18$289
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:00 amSNA - TYS
2 stops12h 07mDelta
Wed 11/512:47 pmTYS - SNA
2 stops12h 41mDelta
Deal found 9/18$299
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:09 pmSNA - TYS
1 stop14h 14mMultiple Airlines
Mon 11/31:23 pmTYS - SNA
2 stops27h 12mMultiple Airlines
Deal found 9/16$300
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/292:20 pmSNA - TYS
1 stop20h 13mMultiple Airlines
Mon 11/31:23 pmTYS - SNA
2 stops27h 12mMultiple Airlines
Deal found 9/16$304
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/112:58 pmSNA - TYS
1 stop21h 35mMultiple Airlines
Sun 10/55:44 pmTYS - SNA
2 stops31h 19mMultiple Airlines
Deal found 9/16$332
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:45 amSNA - TYS
2 stops26h 43mMultiple Airlines
Mon 10/1310:12 pmTYS - SNA
1 stop24h 02mMultiple Airlines
Deal found 9/16$353
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:09 pmSNA - TYS
1 stop14h 14mMultiple Airlines
Sun 11/27:00 amTYS - SNA
2 stops15h 31mMultiple Airlines
Deal found 9/16$360
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:04 pmLGB - TYS
2 stops18h 47mDelta
Mon 11/108:05 pmTYS - LGB
2 stops19h 10mDelta
Deal found 9/17$456
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/84:50 pmLGB - TYS
2 stops13h 46mDelta
Tue 12/165:25 amTYS - LGB
2 stops9h 50mDelta
Deal found 9/17$487
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:04 pmLGB - TYS
2 stops18h 47mDelta
Sat 11/812:47 pmTYS - LGB
2 stops11h 46mDelta
Deal found 9/17$507

Cheapflights Fare Finder

 
Customize your flight search to find flights from Orange County to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Orange County to Knoxville that are best for you.

Fly from

Orange County

Fly to

Knoxville

Route

Depart

Return

Price

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

11:48 am-9:13 pm

1 stop6h 25m

Knoxville McGhee Tyson

Tue 11/4

3:59 pm-10:28 pm

1 stop9h 29m

$289

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 11/8

12:27 pm-12:08 am

1 stop8h 41m

Knoxville McGhee Tyson

Tue 11/11

7:59 am-12:43 pm

1 stop7h 44m

$289

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

1:10 pm-12:23 am

2 stops8h 13m

Knoxville McGhee Tyson

Tue 11/4

5:10 am-9:53 am

1 stop7h 43m

$294

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 11/8

5:40 pm-9:37 am

2 stops12h 57m

Knoxville McGhee Tyson

Tue 11/11

5:36 pm-10:28 pm

1 stop7h 52m

$294

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

1:10 pm-12:23 am

2 stops8h 13m

Knoxville McGhee Tyson

Wed 11/5

3:04 pm-9:39 pm

1 stop9h 35m

$294

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Wed 10/29

2:20 pm-1:33 pm

1 stop20h 13m

Knoxville McGhee Tyson

Mon 11/3

1:23 pm-1:35 pm

2 stops27h 12m

$304

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 11/1

8:00 am-11:07 pm

2 stops12h 07m

Knoxville McGhee Tyson

Wed 11/5

12:47 pm-10:28 pm

2 stops12h 41m

$349

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Wed 10/8

6:45 am-12:28 pm

2 stops26h 43m

Knoxville McGhee Tyson

Mon 10/13

10:12 pm-7:14 pm

1 stop24h 02m

$353

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Fri 10/31

11:10 am-11:59 pm

2 stops9h 49m

Knoxville McGhee Tyson

Tue 11/4

5:45 am-1:03 pm

2 stops10h 18m

$362

Long BeachKnoxville

LGB - TYS

LGBTYS

Long Beach Municipal

Wed 11/5

5:04 pm-2:51 pm

2 stops18h 47m

Knoxville McGhee Tyson

Mon 11/10

8:05 pm-12:15 pm

2 stops19h 10m

$456

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 40 results
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Best time to book a flight from Orange County to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Orange County with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Orange County to Knoxville

What is the cheapest month to book a flight from Orange County to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Orange County to Knoxville (average of $295). Flying from Orange County to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KFI to TYS?

Find hourly flight availability from Orange County to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 19, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Orange County to Knoxville as you normally would.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 19, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Orange County to Knoxville by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,964 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Delta
8.0
Very good
7,964 reviews
Delta
8.0
Very good
7,964 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,964 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,964 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

Related info for your journey

Find useful and relevant information for your journey from Orange County to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Orange County?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Orange County. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Orange County to Knoxville?

    Airlines like Delta and American Airlines fly from Orange County to Knoxville in about 6h 25m. The time it takes to get you to your destination can typically vary by up to 2h 16m. The distance from Orange County to Knoxville is about 1918 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Orange County to Knoxville that include hotel bookings?

    Yes. In addition to deals on Orange County to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Orange County to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Orange County to Knoxville.

  • Can I find deals for business class flights from Orange County to Knoxville?

    Yes. Cheapflights offers flight deals from Orange County to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Orange County to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Orange County to Knoxville (average of $295). Flying from Orange County to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Orange County to Knoxville

Discover the top 3 airlines that operate flights from Orange County to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$363FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$239Average$468FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$277Average$434FlexibilityNo cancel feeOn-time71%

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