$122+ Cheap flights from Panama City, FL to Knoxville (ECP - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — TYS
Aug 31 — Sep 71
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Knoxville
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Best
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One-way
Cheapest flights from Panama City to KnoxvilleExplore the most affordable flight options available from Panama City to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.
Explore the most affordable flight options available from Panama City to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am
ECP
- TYS
1 stop3h 44m
Delta
Tue 9/2210:26 am
TYS
- ECP
1 stop6h 05m
Delta
Deal found 7/29![Delta logo]()
$243
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:15 am
ECP
- TYS
2 stops11h 10m
Southwest
Tue 9/228:05 am
TYS
- ECP
2 stops11h 10m
Southwest
Deal found 7/29![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:19 am
ECP
- TYS
1 stop3h 21m
Delta
Mon 10/265:40 am
TYS
- ECP
1 stop5h 55m
Delta
Deal found 8/1![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:45 am
ECP
- TYS
1 stop4h 38m
Delta
Mon 1/44:00 pm
TYS
- ECP
1 stop4h 36m
Delta
Deal found 7/31![Delta logo]()
$276
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:28 am
ECP
- TYS
1 stop5h 58m
Delta
Tue 11/174:03 pm
TYS
- ECP
1 stop5h 05m
Delta
Deal found 7/31![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:00 am
ECP
- TYS
1 stop7h 00m
Southwest
Tue 11/177:05 am
TYS
- ECP
2 stops9h 30m
Southwest
Deal found 7/31![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:53 pm
ECP
- TYS
1 stop5h 10m
Delta
Fri 8/287:41 pm
TYS
- ECP
1 stop4h 49m
Delta
Deal found 7/30![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:27 am
ECP
- TYS
1 stop5h 03m
Delta
Fri 9/44:38 pm
TYS
- ECP
1 stop2h 57m
Delta
Deal found 7/31![Delta logo]()
$296
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
ECP
- TYS
1 stop6h 25m
Southwest
Fri 8/287:10 am
TYS
- ECP
2 stops14h 50m
Southwest
Deal found 7/30![Southwest logo]()
$300
Best flights from Panama City to KnoxvilleDiscover carefully curated flight deals from Panama City to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 1, 2026.
Discover carefully curated flight deals from Panama City to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 1, 2026.
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:15 am
ECP
- TYS
2 stops11h 10m
Southwest
Tue 9/228:05 am
TYS
- ECP
2 stops11h 10m
Southwest
Deal found 7/29![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:45 am
ECP
- TYS
1 stop4h 38m
Delta
Mon 1/47:20 pm
TYS
- ECP
1 stop4h 27m
Delta
Deal found 7/28![Delta logo]()
$276
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:42 am
ECP
- TYS
1 stop6h 18m
American Airlines
Tue 8/1812:09 pm
TYS
- ECP
1 stop6h 07m
American Airlines
Deal found 7/30![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:28 am
ECP
- TYS
1 stop5h 58m
Delta
Tue 11/174:03 pm
TYS
- ECP
1 stop5h 05m
Delta
Deal found 7/31![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
ECP
- TYS
1 stop6h 25m
Southwest
Fri 8/287:10 am
TYS
- ECP
2 stops14h 50m
Southwest
Deal found 7/30![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:27 am
ECP
- TYS
1 stop5h 03m
Delta
Fri 9/44:38 pm
TYS
- ECP
1 stop2h 57m
Delta
Deal found 7/31![Delta logo]()
$296
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:45 am
ECP
- TYS
1 stop3h 20m
Southwest
Fri 9/187:10 am
TYS
- ECP
1 stop6h 55m
Southwest
Deal found 7/28![Southwest logo]()
$350
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:10 am
ECP
- TYS
2 stops9h 20m
Southwest
Tue 11/177:05 am
TYS
- ECP
2 stops9h 30m
Southwest
Deal found 7/31![Southwest logo]()
$355
Last-minute flights from Panama City to KnoxvilleDiscover last-minute flight deals from Panama City to Knoxville. Data last updated August 1, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Knoxville. Data last updated August 1, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:10 am
ECP
- TYS
2 stops8h 45m
Southwest
Sun 8/165:55 pm
TYS
- ECP
1 stop3h 15m
Southwest
Deal found 7/28![Southwest logo]()
$452
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:40 am
ECP
- TYS
1 stop5h 51m
American Airlines
Thu 8/136:05 pm
TYS
- ECP
1 stop5h 35m
American Airlines
Deal found 7/30![American Airlines logo]()
$447
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Mon 8/177:10 am
TYS
- ECP
1 stop3h 15m
Southwest
Deal found 7/29![Southwest logo]()
$482
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Tue 8/181:55 pm
TYS
- ECP
2 stops7h 35m
Southwest
Deal found 7/30![Southwest logo]()
$457
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:53 pm
ECP
- TYS
1 stop5h 10m
Delta
Fri 8/287:41 pm
TYS
- ECP
1 stop4h 49m
Delta
Deal found 7/30![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
ECP
- TYS
1 stop6h 25m
Southwest
Fri 8/287:10 am
TYS
- ECP
2 stops14h 50m
Southwest
Deal found 7/30![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:00 am
ECP
- TYS
1 stop4h 11m
Delta
Sat 8/296:00 am
TYS
- ECP
1 stop5h 42m
Delta
Deal found 7/30![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:10 am
ECP
- TYS
1 stop3h 15m
Southwest
Sat 8/296:50 am
TYS
- ECP
2 stops9h 05m
Southwest
Deal found 7/30![Southwest logo]()
$400
One-way flights from Panama City to KnoxvilleSearch for one-way flight options from Panama City to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 1, 2026.
Search for one-way flight options from Panama City to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 1, 2026.
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:48 pm
ECP
- TYS
1 stop4h 10m
American Airlines
Deal found 7/28![American Airlines logo]()
$122
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Deal found 7/28![Southwest logo]()
$127
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:32 pm
ECP
- TYS
1 stop6h 34m
American Airlines
Deal found 7/31![American Airlines logo]()
$135
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:20 pm
ECP
- TYS
1 stop4h 39m
Delta
Deal found 7/28![Delta logo]()
$145
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:15 am
ECP
- TYS
2 stops13h 15m
Southwest
Deal found 7/28![Southwest logo]()
$156
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:35 am
ECP
- TYS
1 stop3h 31m
Delta
Deal found 7/31![Delta logo]()
$162
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:30 am
ECP
- TYS
2 stops7h 30m
Southwest
Deal found 7/31![Southwest logo]()
$179
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/303:15 pm
ECP
- TYS
1 stop4h 30m
Southwest
Deal found 7/28![Southwest logo]()
$184
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:05 am
ECP
- TYS
2 stops9h 05m
Southwest
Deal found 8/1![Southwest logo]()
$189
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am
ECP
- TYS
1 stop4h 18m
Delta
Deal found 7/29![Delta logo]()
$240
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:20 pm
ECP
- TYS
1 stop4h 35m
Delta
Deal found 8/1![Delta logo]()
$243
Find flight deals from Panama City to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (Delta) |
One-way from | $122 (American Airlines) |
Popular in | September |
Cheapest in | June |
Average price | $328 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Panama City to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Sat 9/19
7:15 am-7:25 pm
2 stops11h 10m
Knoxville McGhee Tyson
Tue 9/22
8:05 am-6:15 pm
2 stops11h 10m
$253
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Thu 12/31
7:45 am-1:23 pm
1 stop4h 38m
Knoxville McGhee Tyson
Mon 1/4
7:20 pm-10:47 pm
1 stop4h 27m
$276
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Fri 11/13
11:28 am-6:26 pm
1 stop5h 58m
Knoxville McGhee Tyson
Tue 11/17
4:03 pm-8:08 pm
1 stop5h 05m
$279
Quickest round-trip
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Tue 9/1
9:27 am-3:30 pm
1 stop5h 03m
Knoxville McGhee Tyson
Fri 9/4
4:38 pm-6:35 pm
1 stop2h 57m
$296
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Fri 8/21
6:00 am-1:25 pm
1 stop6h 25m
Knoxville McGhee Tyson
Fri 8/28
7:10 am-9:00 pm
2 stops14h 50m
$300
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Tue 9/15
7:45 am-12:05 pm
1 stop3h 20m
Knoxville McGhee Tyson
Fri 9/18
7:10 am-1:05 pm
1 stop6h 55m
$350
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Fri 11/13
10:10 am-8:30 pm
2 stops9h 20m
Knoxville McGhee Tyson
Tue 11/17
7:05 am-3:35 pm
2 stops9h 30m
$355
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Fri 8/14
11:42 am-7:00 pm
1 stop6h 18m
Knoxville McGhee Tyson
Tue 8/18
12:09 pm-5:16 pm
1 stop6h 07m
$447
Cheapest one-way
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Sat 9/26
6:00 am-10:44 am
1 stop3h 44m
$122
Panama CityKnoxville
ECP - TYS
ECPTYS
Panama City NW Florida Beaches
Sat 9/26
7:15 am-7:25 pm
2 stops11h 10m
$127
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Panama City to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Knoxville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Panama City with our price prediction graph.
ECP-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 1, 2026.
Read through reviews of airlines operating flights from Panama City to Knoxville, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 1, 2026.
Panama City and Knoxville flights
Browse other Panama City and Knoxville flight options. Last updated on August 1, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on August 1, 2026.
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Top airline flying from Panama City to Knoxville
Discover the top airline that operate flights from Panama City to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$211 | Average$376 | FlexibilityNo cancel fee | On-timeN/A |