$80+ Cheap flights from Minneapolis to Knoxville (MSP - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — TYS
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Minneapolis St Paul to Knoxville McGhee Tyson are usually found in July or June, booked 62 days in advance, depart on a Friday or Monday and return on a Friday
Cheap flight deals from Minneapolis to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Minneapolis to KnoxvilleExplore the most affordable flight options available from Minneapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Minneapolis to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Thu 4/304:28 pm
TYS
- MSP
1 stop8h 30m
Frontier
Deal found 3/9![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Thu 5/74:28 pm
TYS
- MSP
1 stop8h 30m
Frontier
Deal found 3/8![Frontier logo]()
$181
This Priceline deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Sun 5/104:28 pm
TYS
- MSP
1 stop8h 30m
Frontier
Deal found 3/9![Frontier logo]()
$215
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:15 pm
MSP
- TYS
1 stop4h 25m
Southwest
Wed 4/155:50 pm
TYS
- MSP
1 stop6h 15m
Southwest
Deal found 3/9![Southwest logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:45 am
MSP
- TYS
1 stop10h 39m
Multiple Airlines
Fri 5/151:15 pm
TYS
- MSP
1 stop21h 35m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:45 am
MSP
- TYS
1 stop7h 48m
Multiple Airlines
Mon 5/111:15 pm
TYS
- MSP
1 stop23h 17m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$299
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Sun 4/194:28 pm
TYS
- MSP
1 stop8h 30m
Frontier
Deal found 3/9![Frontier logo]()
$310
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:15 am
MSP
- TYS
2 stops11h 25m
Southwest
Wed 4/16:35 am
TYS
- MSP
2 stops11h 45m
Southwest
Deal found 3/5![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:15 am
MSP
- TYS
1 stop4h 25m
Southwest
Tue 5/128:15 am
TYS
- MSP
1 stop7h 20m
Southwest
Deal found 3/9![Southwest logo]()
$313
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:40 am
MSP
- TYS
1 stop7h 51m
American Airlines
Tue 4/76:05 am
TYS
- MSP
1 stop6h 52m
American Airlines
Deal found 3/5![American Airlines logo]()
$317
Best flights from Minneapolis to KnoxvilleDiscover carefully curated flight deals from Minneapolis to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Minneapolis to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:05 am
MSP
- TYS
2 stops8h 35m
Southwest
Tue 4/2112:50 pm
TYS
- MSP
2 stops10h 45m
Southwest
Deal found 3/9![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:45 pm
MSP
- TYS
Nonstop2h 11m
Delta
Fri 6/266:15 pm
TYS
- MSP
Nonstop2h 32m
Delta
Deal found 3/6![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:32 am
MSP
- TYS
1 stop4h 40m
United Airlines
Sun 5/316:30 am
TYS
- MSP
1 stop5h 06m
United Airlines
Deal found 3/8![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:30 pm
MSP
- TYS
Nonstop2h 13m
Delta
Wed 4/156:15 am
TYS
- MSP
Nonstop2h 29m
Delta
Deal found 3/9![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:20 pm
MSP
- TYS
2 stops9h 00m
Southwest
Tue 6/97:10 am
TYS
- MSP
2 stops10h 05m
Southwest
Deal found 3/9![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:45 pm
MSP
- TYS
Nonstop2h 11m
Delta
Sat 8/296:45 am
TYS
- MSP
Nonstop2h 29m
Delta
Deal found 3/8![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:45 pm
MSP
- TYS
Nonstop2h 14m
Delta
Sat 5/97:50 am
TYS
- MSP
1 stop6h 45m
Delta
Deal found 3/5![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:08 pm
MSP
- TYS
1 stop6h 48m
United Airlines
Sun 5/316:30 am
TYS
- MSP
1 stop5h 06m
United Airlines
Deal found 3/8![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:20 am
MSP
- TYS
2 stops11h 00m
Southwest
Wed 4/157:05 am
TYS
- MSP
2 stops9h 45m
Southwest
Deal found 3/6![Southwest logo]()
$380
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:41 pm
MSP
- TYS
1 stop6h 16m
Delta
Wed 4/156:15 am
TYS
- MSP
Nonstop2h 29m
Delta
Deal found 3/6![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:45 pm
MSP
- TYS
Nonstop2h 11m
Delta
Mon 6/296:15 pm
TYS
- MSP
Nonstop2h 32m
Delta
Deal found 3/8![Delta logo]()
$339
Last-minute flights from Minneapolis to KnoxvilleDiscover last-minute flight deals from Minneapolis to Knoxville. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to Knoxville. Data last updated March 10, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:15 am
MSP
- TYS
2 stops11h 25m
Southwest
Wed 4/16:35 am
TYS
- MSP
2 stops11h 45m
Southwest
Deal found 3/5![Southwest logo]()
$311
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:40 am
MSP
- TYS
1 stop7h 51m
American Airlines
Tue 4/76:05 am
TYS
- MSP
1 stop6h 52m
American Airlines
Deal found 3/5![American Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:15 pm
MSP
- TYS
1 stop4h 25m
Southwest
Wed 4/155:50 pm
TYS
- MSP
1 stop6h 15m
Southwest
Deal found 3/9![Southwest logo]()
$295
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:10 am
MSP
- TYS
1 stop3h 50m
Southwest
Sat 4/116:40 am
TYS
- MSP
1 stop8h 30m
Southwest
Deal found 3/9![Southwest logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:48 am
MSP
- TYS
1 stop6h 53m
Multiple Airlines
Thu 4/164:28 pm
TYS
- MSP
1 stop8h 30m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:15 am
MSP
- TYS
1 stop4h 25m
Southwest
Wed 4/158:15 am
TYS
- MSP
1 stop7h 20m
Southwest
Deal found 3/6![Southwest logo]()
$313
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Sun 4/194:28 pm
TYS
- MSP
1 stop8h 30m
Frontier
Deal found 3/9![Frontier logo]()
$310
This Frontier deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Thu 4/234:28 pm
TYS
- MSP
1 stop8h 30m
Frontier
Deal found 3/8![Frontier logo]()
$215
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:45 pm
MSP
- TYS
Nonstop2h 14m
Delta
Tue 4/286:15 am
TYS
- MSP
Nonstop2h 29m
Delta
Deal found 3/6![Delta logo]()
$319
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Thu 4/304:28 pm
TYS
- MSP
1 stop8h 30m
Frontier
Deal found 3/9![Frontier logo]()
$160
One-way flights from Minneapolis to KnoxvilleSearch for one-way flight options from Minneapolis to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Minneapolis to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Deal found 3/5![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Deal found 3/9![Frontier logo]()
$90
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:45 am
MSP
- TYS
1 stop7h 48m
Frontier
Deal found 3/5![Frontier logo]()
$101
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:55 am
MSP
- TYS
1 stop11h 18m
Frontier
Deal found 3/6![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:42 pm
MSP
- TYS
1 stop19h 54m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:48 pm
MSP
- TYS
1 stop24h 04m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:24 am
MSP
- TYS
1 stop27h 29m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$146
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:10 am
MSP
- TYS
1 stop3h 50m
Southwest
Deal found 3/8![Southwest logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:00 am
MSP
- TYS
1 stop23h 36m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$156
Find flight deals from Minneapolis to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $160 (Frontier) |
One-way from | $80 (Frontier) |
Popular in | January |
Cheapest in | July |
Average price | $417 |
Good round-trip deal | $359 or less |
Good one-way deal | $348 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Minneapolis to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Tue 4/14
10:05 am-7:40 pm
2 stops8h 35m
Knoxville McGhee Tyson
Tue 4/21
12:50 pm-10:35 pm
2 stops10h 45m
$305
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Fri 6/19
7:45 pm-10:56 pm
Nonstop2h 11m
Knoxville McGhee Tyson
Fri 6/26
6:15 pm-7:47 pm
Nonstop2h 32m
$319
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Sat 4/11
7:30 pm-10:43 pm
Nonstop2h 13m
Knoxville McGhee Tyson
Wed 4/15
6:15 am-7:44 am
Nonstop2h 29m
$319
Quickest round-trip
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Sat 8/22
7:45 pm-10:56 pm
Nonstop2h 11m
Knoxville McGhee Tyson
Sat 8/29
6:45 am-8:14 am
Nonstop2h 29m
$319
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Fri 6/5
12:20 pm-10:20 pm
2 stops9h 00m
Knoxville McGhee Tyson
Tue 6/9
7:10 am-4:15 pm
2 stops10h 05m
$327
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Tue 5/5
7:45 pm-10:59 pm
Nonstop2h 14m
Knoxville McGhee Tyson
Sat 5/9
7:50 am-1:35 pm
1 stop6h 45m
$329
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Fri 4/10
4:41 pm-11:57 pm
1 stop6h 16m
Knoxville McGhee Tyson
Wed 4/15
6:15 am-7:44 am
Nonstop2h 29m
$329
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Thu 6/25
7:45 pm-10:56 pm
Nonstop2h 11m
Knoxville McGhee Tyson
Mon 6/29
6:15 pm-7:47 pm
Nonstop2h 32m
$339
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Fri 4/10
8:20 am-8:20 pm
2 stops11h 00m
Knoxville McGhee Tyson
Wed 4/15
7:05 am-3:50 pm
2 stops9h 45m
$380
MinneapolisKnoxville
MSP - TYS
MSPTYS
Minneapolis St Paul
Wed 5/27
11:32 am-5:12 pm
1 stop4h 40m
Knoxville McGhee Tyson
Sun 5/31
6:30 am-10:36 am
1 stop5h 06m
$404
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Minneapolis to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Knoxville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Minneapolis-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Minneapolis-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Minneapolis-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Minneapolis-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Minneapolis to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Minneapolis with our price prediction graph.
MSP-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to Knoxville
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How far ahead should I book a flight from Minneapolis to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from Minneapolis to Knoxville. Price data was last updated on March 6, 2026.
The price you pay for your flight from Minneapolis to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Minneapolis to Knoxville?
Currently, June is the cheapest month in which you can book a flight from Minneapolis to Knoxville (average of $49). Flying from Minneapolis to Knoxville in January is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MSP to TYS?
Find hourly flight availability from Minneapolis to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 10, 2026.
One of the essential ways to save on airfare from Minneapolis to Knoxville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 72% on airfare.
What’s the top layover airport for flights from Minneapolis to Knoxville?
Share of 1-stop round-trip flights from Minneapolis to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Nashville (BNA) – chosen by Cheapflights users on 50% of 1-stop itineraries from Minneapolis to Knoxville on Cheapflights.
What’s the cheapest layover airport for flights from Minneapolis to Knoxville?
Average round-trip fare for 1-stop flights from Minneapolis to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $239.
What’s the fastest layover option from Minneapolis to Knoxville?
Shortest average travel time for 1-stop one-way flights from Minneapolis to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Nashville (BNA) have the shortest average one-way travel time for 1-stop routes: 3h 57m.
Which airport typically offers the quickest layover for flights from Minneapolis to Knoxville?
Average layover duration for 1-stop one-way flights from Minneapolis to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 06m.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 10, 2026.
Read through reviews of airlines operating flights from Minneapolis to Knoxville, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Top 5 airlines flying from Minneapolis to Knoxville
Discover the top 5 airlines that operate flights from Minneapolis to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$62 | Average$114 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$286 | Average$388 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$400 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$418 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$355 | Average$412 | FlexibilityNo cancel fee | On-time63% |