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$55+ Cheap flights from Massachusetts to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — TYS
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Massachusetts to Knoxville

Cheapest flights from Massachusetts to Knoxville
Explore the most affordable flight options available from Massachusetts to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Gotogate deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:00 amBOS - TYS
Nonstop2h 31mAllegiant Air
Sat 12/207:00 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/14$177
This Booking.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:45 pmBOS - TYS
Nonstop2h 31mAllegiant Air
Tue 12/306:00 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/14$231
This Mytrip deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:00 amBOS - TYS
Nonstop2h 31mAllegiant Air
Sun 12/216:00 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/13$236
This Booking.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amBOS - TYS
Nonstop2h 31mAllegiant Air
Sun 1/46:00 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/14$257
This Booking.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:00 amBOS - TYS
Nonstop2h 31mAllegiant Air
Thu 1/19:45 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/14$268
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1412:57 pmBOS - TYS
1 stop28h 23mMultiple Airlines
Sun 12/216:00 amTYS - BOS
Nonstop2h 10mMultiple Airlines
Deal found 12/13$281
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:00 amBOS - TYS
Nonstop2h 31mMultiple Airlines
Sat 12/203:34 pmTYS - BOS
1 stop19h 16mMultiple Airlines
Deal found 12/14$293
This Mytrip deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:00 amBOS - TYS
Nonstop2h 31mAllegiant Air
Tue 12/236:00 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/14$298
This Booking.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:00 amBOS - TYS
Nonstop2h 31mAllegiant Air
Sun 1/46:00 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/14$306
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:30 pmBOS - TYS
1 stop5h 13mAmerican Airlines
Wed 1/76:00 amTYS - BOS
1 stop8h 13mAmerican Airlines
Deal found 12/13$307
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:04 pmBDL - TYS
1 stop5h 39mAmerican Airlines
Tue 12/305:42 amTYS - BDL
1 stop5h 16mAmerican Airlines
Deal found 12/13$315
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amBDL - TYS
1 stop8h 28mAmerican Airlines
Fri 1/25:42 amTYS - BDL
1 stop5h 16mAmerican Airlines
Deal found 12/12$346

Find flight deals from Massachusetts to Knoxville

Keep the following information in mind while searching for Massachusetts to Knoxville flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$96
(Booking.com)

One-way from

$55
(Booking.com)

Popular in

January

Cheapest in

February

Average price

$367

Good round-trip deal

$166 or less

Good one-way deal

$75 or less
Provider with most accurate pricing for Boston Logan Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Boston Logan Intl-Knoxville McGhee Tyson flights.
Search Deals
From Massachusetts to Knoxville McGhee Tyson
Search Deals
One-way flight from Massachusetts to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Massachusetts to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Massachusetts to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Massachusetts to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Massachusetts to Knoxville that are best for you.

Fly from

Massachusetts

Fly to

Knoxville

Route

Depart

Return

Price

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 2/19

9:29 am-12:12 pm

Nonstop2h 43m

Knoxville McGhee Tyson

Sun 2/22

6:30 am-8:39 am

Nonstop2h 09m

$130

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 4/16

9:06 am-11:35 am

Nonstop2h 29m

Knoxville McGhee Tyson

Sun 4/19

6:00 am-8:16 am

Nonstop2h 16m

$188

HartfordKnoxville

BDL - TYS

BDLTYS

Hartford Bradley Intl

Tue 1/13

6:00 am-10:57 am

1 stop4h 57m

Knoxville McGhee Tyson

Tue 1/20

7:20 pm-11:44 pm

1 stop4h 24m

$199

HartfordKnoxville

BDL - TYS

BDLTYS

Hartford Bradley Intl

Wed 1/14

6:00 am-10:57 am

1 stop4h 57m

Knoxville McGhee Tyson

Sat 1/17

7:20 pm-11:44 pm

1 stop4h 24m

$199

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Wed 1/14

5:23 pm-5:53 pm

2 stops24h 30m

Knoxville McGhee Tyson

Mon 1/26

12:55 pm-2:38 pm

1 stop25h 43m

$203

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 2/19

9:29 am-12:12 pm

Nonstop2h 43m

Knoxville McGhee Tyson

Sun 2/22

5:56 pm-4:28 pm

2 stops46h 32m

$206

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Sun 1/11

3:43 pm-5:28 pm

1 stop25h 45m

Knoxville McGhee Tyson

Wed 1/14

4:47 pm-11:57 pm

1 stop7h 10m

$207

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Fri 1/9

5:27 pm-11:09 am

1 stop17h 42m

Knoxville McGhee Tyson

Mon 1/12

12:55 pm-2:38 pm

1 stop25h 43m

$228

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 1/1

12:45 pm-3:16 pm

Nonstop2h 31m

Knoxville McGhee Tyson

Sun 1/4

10:03 pm-1:19 am

2 stops51h 16m

$229

HartfordKnoxville

BDL - TYS

BDLTYS

Hartford Bradley Intl

Thu 1/1

10:36 am-2:48 pm

1 stop4h 12m

Knoxville McGhee Tyson

Thu 1/1

7:23 pm-11:58 pm

1 stop4h 35m

$236

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 44 results
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Best time to book a flight from Massachusetts to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Knoxville

What is the cheapest month to book a flight from Massachusetts to Knoxville?

Currently, May is the cheapest month in which you can book a flight from Massachusetts to Knoxville (average of $54). Flying from Massachusetts to Knoxville in January is currently the most expensive (average of $140). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA to TYS?

Find hourly flight availability from Massachusetts to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

It’s typically best to fly out from Massachusetts to Knoxville in the morning. Doing so could potentially save you 68% on the flight price compared to flying in the evening, which is usually more expensive.

What is the cheapest day to fly from Massachusetts to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Massachusetts to Knoxville. Price data was last updated on December 13, 2025.

Travelers seeking maximum savings on their Massachusetts to Knoxville flight should consider departing on Wednesday mornings when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Massachusetts to Knoxville?

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Massachusetts?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Massachusetts. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How popular is this Massachusetts to Knoxville flight route?

    Flights from Massachusetts to Knoxville McGhee Tyson have been viewed 2 times in the past calendar month.

  • How long is the flight from Massachusetts to Knoxville?

    Departing from Massachusetts to Knoxville will take you 2h 43m. The distance between Massachusetts and Knoxville is about 829 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Massachusetts to Knoxville one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $51. United Airlines flights start at $139 while deals on American Airlines start at $157 one-way.

  • What are the most popular routes from Massachusetts to Knoxville?

    Most travelers choose Boston Logan Intl - Knoxville McGhee Tyson, Hartford Bradley Intl - Knoxville McGhee Tyson or Albany Intl - Knoxville McGhee Tyson when deciding on the best route from Massachusetts to Knoxville.

  • What are the cheapest flights from Massachusetts to Knoxville?

    The cheapest flight price from Massachusetts to Knoxville is $65. On average you can expect to pay $198. The most popular route, (Boston Logan Intl - Knoxville McGhee Tyson), can usually be booked for $123.

  • Can I find deals for flights from Massachusetts to Knoxville that include hotel bookings?

    Yes. In addition to deals on Massachusetts to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Massachusetts to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Knoxville.

  • Can I find deals for business class flights from Massachusetts to Knoxville?

    Yes. Cheapflights offers flight deals from Massachusetts to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Massachusetts to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from Massachusetts to Knoxville (average of $54). Flying from Massachusetts to Knoxville in January is currently the most expensive (average of $140). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Massachusetts to Knoxville

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Top 4 airlines flying from Massachusetts to Knoxville

Discover the top 4 airlines that operate flights from Massachusetts to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$89Average$190FlexibilityNo cancel feeOn-time88%
DeltaCheapest$230Average$500FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$447FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$446FlexibilityNo cancel feeOn-time69%

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