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Knoxville

$94+ Cheap flights from Louisiana to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Louisiana to Knoxville

Keep the following information in mind while searching for Louisiana to Knoxville flight deals. Data was last updated June 12, 2025.

Round-trip from

$179
(Mytrip)

One-way from

$94
(Mytrip)

Popular in

December

Cheapest in

January

Average price

$368
From Louisiana to Knoxville McGhee Tyson
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One-way flight from Louisiana to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 4% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Louisiana to Knoxville

Cheapest flights from Louisiana to Knoxville
Explore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1712:48 pmMSY - TYS
1 stop9h 49mMultiple Airlines
Mon 7/215:02 pmTYS - MSY
1 stop14h 53mMultiple Airlines
Deal found 6/10$179
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/510:43 amMSY - TYS
1 stop6h 19mAmerican Airlines
Wed 7/92:48 pmTYS - MSY
1 stop6h 41mAmerican Airlines
Deal found 6/9$224
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1010:41 amLFT - TYS
1 stop5h 51mAmerican Airlines
Sun 7/136:00 amTYS - LFT
1 stop5h 11mAmerican Airlines
Deal found 6/12$249
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/91:06 pmSHV - TYS
1 stop4h 55mDelta
Thu 7/175:30 amTYS - SHV
1 stop6h 05mDelta
Deal found 6/10$249
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:32 pmBTR - TYS
1 stop4h 37mAmerican Airlines
Mon 9/157:45 pmTYS - BTR
1 stop4h 21mAmerican Airlines
Deal found 6/12$249
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/278:23 amSHV - TYS
1 stop14h 14mAllegiant Air
Wed 7/301:01 pmTYS - SHV
1 stop19h 32mAllegiant Air
Deal found 6/11$262
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/256:25 pmSHV - TYS
1 stop4h 27mAmerican Airlines
Tue 7/296:00 amTYS - SHV
1 stop4h 53mAmerican Airlines
Deal found 6/11$279
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/205:25 amMSY - TYS
1 stop3h 28mDelta
Wed 6/254:11 pmTYS - MSY
1 stop5h 04mDelta
Deal found 6/12$284
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/187:00 pmBTR - TYS
1 stop3h 59mDelta
Fri 7/256:19 pmTYS - BTR
1 stop4h 39mDelta
Deal found 6/11$294
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/272:06 pmSHV - TYS
2 stops30h 14mMultiple Airlines
Wed 7/304:09 pmTYS - SHV
3 stops22h 07mMultiple Airlines
Deal found 6/11$323
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/12:16 pmMSY - TYS
1 stop7h 19mUnited Airlines
Thu 7/312:00 pmTYS - MSY
1 stop24h 03mUnited Airlines
Deal found 6/9$391
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/152:14 pmBTR - TYS
1 stop4h 42mUnited Airlines
Tue 6/1712:00 pmTYS - BTR
1 stop6h 43mUnited Airlines
Deal found 6/11$469

Cheapflights Fare Finder

Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Louisiana

Fly to

Knoxville

Route

Depart

Return

Price

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Thu 7/17

12:48 pm-11:37 pm

1 stop9h 49m

Knoxville McGhee Tyson

Mon 7/21

5:02 pm-6:55 am

1 stop14h 53m

$179

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Sat 7/5

10:43 am-6:02 pm

1 stop6h 19m

Knoxville McGhee Tyson

Wed 7/9

2:48 pm-8:29 pm

1 stop6h 41m

$224

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Wed 7/9

1:06 pm-7:01 pm

1 stop4h 55m

Knoxville McGhee Tyson

Thu 7/17

5:30 am-10:35 am

1 stop6h 05m

$249

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Thu 7/10

10:41 am-5:32 pm

1 stop5h 51m

Knoxville McGhee Tyson

Sun 7/13

6:00 am-10:11 am

1 stop5h 11m

$249

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Thu 9/11

6:32 pm-12:09 am

1 stop4h 37m

Knoxville McGhee Tyson

Mon 9/15

7:45 pm-11:06 pm

1 stop4h 21m

$249

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Sun 7/27

8:23 am-11:37 pm

1 stop14h 14m

Knoxville McGhee Tyson

Wed 7/30

1:01 pm-7:33 am

1 stop19h 32m

$262

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Fri 7/25

6:25 pm-11:52 pm

1 stop4h 27m

Knoxville McGhee Tyson

Tue 7/29

6:00 am-9:53 am

1 stop4h 53m

$279

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 6/20

5:25 am-9:53 am

1 stop3h 28m

Knoxville McGhee Tyson

Wed 6/25

4:11 pm-8:15 pm

1 stop5h 04m

$284

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Fri 7/18

7:00 pm-11:59 pm

1 stop3h 59m

Knoxville McGhee Tyson

Fri 7/25

6:19 pm-9:58 pm

1 stop4h 39m

$294

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Sun 7/27

2:06 pm-9:20 pm

2 stops30h 14m

Knoxville McGhee Tyson

Wed 7/30

4:09 pm-1:16 pm

3 stops22h 07m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 22 results
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Best time to book a flight from Louisiana to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Knoxville

What is the cheapest month to book a flight from Louisiana to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $296). Flying from Louisiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LA to TYS?

Find hourly flight availability from Louisiana to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Louisiana to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta and United Airlines from Louisiana to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Allegiant Air
7.3
Good
725 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Louisiana?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Louisiana to Knoxville. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • What are the cheapest airlines to fly from Louisiana to Knoxville one-way?

    One-way options have recently been found by users for as low as $155 on Delta. Other airlines that offer cheap prices include American Airlines from $239 and United Airlines from $348 one-way.

  • What are the most popular routes from Louisiana to Knoxville?

    The most popular route from Louisiana to Knoxville is New Orleans Louis Armstrong - Knoxville McGhee Tyson. You may also consider Shreveport - Knoxville McGhee Tyson or Lafayette Regional - Knoxville McGhee Tyson.

  • Can I find deals for flights from Louisiana to Knoxville that include hotel bookings?

    Yes. In addition to deals on Louisiana to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Knoxville.

  • Can I find deals for business class flights from Louisiana to Knoxville?

    Yes. Cheapflights offers flight deals from Louisiana to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $296). Flying from Louisiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisiana?

Book flights to Louisiana if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Louisiana to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisiana to Knoxville

Discover the top 3 airlines that operate flights from Louisiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$104Average$361FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$381FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$216Average$374FlexibilityNo cancel feeOn-time71%

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