$109+ Cheap flights from Louisiana to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Apr 4 — Apr 111
Round-trip
1 adult, Economy
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Cheapest flights from Louisiana to KnoxvilleExplore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.
Explore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:10 pm
MSY
- TYS
1 stop14h 26m
Multiple Airlines
Tue 4/72:56 pm
TYS
- MSY
1 stop18h 23m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:00 am
MSY
- TYS
1 stop13h 51m
Multiple Airlines
Mon 3/307:40 am
TYS
- MSY
1 stop25h 39m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:10 pm
MSY
- TYS
1 stop12h 00m
Multiple Airlines
Mon 3/307:40 am
TYS
- MSY
1 stop25h 39m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:10 pm
MSY
- TYS
1 stop26h 16m
Multiple Airlines
Mon 3/307:40 am
TYS
- MSY
1 stop25h 39m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
MSY
- TYS
1 stop25h 18m
Multiple Airlines
Mon 3/307:40 am
TYS
- MSY
1 stop25h 39m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:10 pm
MSY
- TYS
1 stop24h 41m
Multiple Airlines
Tue 3/313:00 pm
TYS
- MSY
1 stop8h 44m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:18 pm
MSY
- TYS
1 stop27h 21m
Multiple Airlines
Wed 4/84:25 pm
TYS
- MSY
1 stop7h 19m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:20 am
MSY
- TYS
1 stop12h 14m
Multiple Airlines
Wed 4/84:25 pm
TYS
- MSY
1 stop7h 19m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:25 pm
BTR
- TYS
1 stop4h 28m
American Airlines
Sat 8/158:25 pm
TYS
- BTR
1 stop4h 17m
American Airlines
Deal found 3/1![American Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
SHV
- TYS
1 stop4h 30m
American Airlines
Wed 4/86:00 am
TYS
- SHV
1 stop5h 03m
American Airlines
Deal found 3/3![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:34 am
SHV
- TYS
1 stop6h 30m
American Airlines
Tue 4/146:00 am
TYS
- SHV
1 stop5h 03m
American Airlines
Deal found 2/28![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:57 pm
BTR
- TYS
1 stop4h 54m
American Airlines
Sat 4/116:00 am
TYS
- BTR
1 stop5h 02m
American Airlines
Deal found 3/2![American Airlines logo]()
$286
Best flights from Louisiana to KnoxvilleDiscover carefully curated flight deals from Louisiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 5, 2026.
Discover carefully curated flight deals from Louisiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 5, 2026.
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:05 pm
BTR
- TYS
1 stop3h 52m
Delta
Wed 4/85:10 pm
TYS
- BTR
1 stop5h 53m
Delta
Deal found 3/2![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:20 pm
LFT
- TYS
1 stop4h 31m
American Airlines
Tue 3/245:05 am
TYS
- LFT
1 stop5h 53m
American Airlines
Deal found 3/4![American Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/271:05 pm
MSY
- TYS
2 stops7h 10m
Southwest
Tue 3/316:35 am
TYS
- MSY
2 stops8h 15m
Southwest
Deal found 3/2![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:44 pm
MSY
- TYS
2 stops8h 50m
United Airlines
Sat 5/99:50 am
TYS
- MSY
1 stop6h 06m
United Airlines
Deal found 3/2![United Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:21 pm
MSY
- TYS
1 stop20h 06m
Multiple Airlines
Tue 3/104:05 pm
TYS
- MSY
1 stop17h 16m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$438
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/312:40 pm
MSY
- TYS
1 stop5h 05m
Southwest
Sun 4/56:35 am
TYS
- MSY
1 stop3h 50m
Southwest
Deal found 3/3![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:12 pm
LFT
- TYS
1 stop5h 45m
Delta
Sat 3/218:45 am
TYS
- LFT
1 stop6h 34m
Delta
Deal found 3/2![Delta logo]()
$356
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:35 pm
SHV
- TYS
1 stop4h 55m
United Airlines
Wed 8/2612:05 pm
TYS
- SHV
1 stop6h 05m
United Airlines
Deal found 3/3![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:55 am
MSY
- TYS
2 stops8h 55m
Southwest
Tue 6/27:05 am
TYS
- MSY
2 stops8h 15m
Southwest
Deal found 2/28![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:08 pm
BTR
- TYS
1 stop4h 33m
United Airlines
Tue 4/147:05 am
TYS
- BTR
1 stop5h 16m
United Airlines
Deal found 3/4![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:34 pm
LFT
- TYS
1 stop5h 19m
American Airlines
Sun 5/245:36 am
TYS
- LFT
1 stop5h 45m
American Airlines
Deal found 3/2![American Airlines logo]()
$402
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
BTR
- TYS
1 stop6h 25m
Delta
Sun 7/195:30 am
TYS
- BTR
1 stop5h 04m
Delta
Deal found 3/1![Delta logo]()
$383
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:05 pm
MSY
- TYS
2 stops7h 10m
Southwest
Mon 3/237:25 pm
TYS
- MSY
1 stop5h 45m
Southwest
Deal found 2/28![Southwest logo]()
$364
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:00 pm
SHV
- TYS
1 stop4h 24m
American Airlines
Mon 4/204:09 pm
TYS
- SHV
1 stop6h 48m
American Airlines
Deal found 3/1![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:36 pm
BTR
- TYS
1 stop4h 51m
Delta
Mon 3/235:10 pm
TYS
- BTR
1 stop5h 53m
Delta
Deal found 3/4![Delta logo]()
$386
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:05 pm
MSY
- TYS
2 stops7h 10m
Southwest
Mon 3/307:25 pm
TYS
- MSY
1 stop5h 45m
Southwest
Deal found 3/3![Southwest logo]()
$364
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:30 pm
LFT
- TYS
1 stop5h 15m
American Airlines
Tue 7/75:31 pm
TYS
- LFT
1 stop7h 25m
American Airlines
Deal found 3/1![American Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/218:00 am
SHV
- TYS
1 stop6h 06m
Delta
Sun 6/285:30 am
TYS
- SHV
1 stop5h 37m
Delta
Deal found 3/1![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:05 am
MSY
- TYS
2 stops9h 15m
Southwest
Fri 4/176:45 pm
TYS
- MSY
2 stops5h 50m
Southwest
Deal found 3/2![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:28 am
LFT
- TYS
1 stop6h 03m
American Airlines
Sun 4/55:40 am
TYS
- LFT
1 stop5h 18m
American Airlines
Deal found 3/3![American Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:20 am
SHV
- TYS
2 stops16h 48m
United Airlines
Wed 4/89:00 am
TYS
- SHV
1 stop7h 31m
United Airlines
Deal found 3/3![United Airlines logo]()
$465
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:30 am
MSY
- TYS
2 stops9h 00m
Southwest
Sun 5/316:40 am
TYS
- MSY
2 stops8h 10m
Southwest
Deal found 3/1![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:00 pm
LFT
- TYS
1 stop5h 51m
Delta
Mon 4/65:40 am
TYS
- LFT
1 stop6h 06m
Delta
Deal found 2/28![Delta logo]()
$405
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:20 pm
LFT
- TYS
1 stop4h 31m
American Airlines
Mon 3/234:29 pm
TYS
- LFT
1 stop7h 29m
American Airlines
Deal found 3/4![American Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2512:35 pm
MSY
- TYS
2 stops6h 30m
Southwest
Mon 3/306:30 am
TYS
- MSY
2 stops7h 00m
Southwest
Deal found 3/1![Southwest logo]()
$377
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:05 am
MSY
- TYS
2 stops9h 15m
Southwest
Sun 4/193:50 pm
TYS
- MSY
2 stops8h 55m
Southwest
Deal found 2/28![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:29 pm
LFT
- TYS
1 stop27h 12m
United Airlines
Mon 4/64:30 pm
TYS
- LFT
2 stops19h 46m
United Airlines
Deal found 2/28![United Airlines logo]()
$557
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:00 am
SHV
- TYS
1 stop4h 25m
Delta
Fri 6/1911:30 am
TYS
- SHV
2 stops13h 00m
Delta
Deal found 3/3![Delta logo]()
$474
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:50 am
MSY
- TYS
2 stops7h 20m
Southwest
Thu 4/166:45 pm
TYS
- MSY
2 stops5h 50m
Southwest
Deal found 3/3![Southwest logo]()
$390
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:30 pm
SHV
- TYS
1 stop4h 26m
American Airlines
Sun 5/176:00 am
TYS
- SHV
1 stop5h 03m
American Airlines
Deal found 3/4![American Airlines logo]()
$520
Last-minute flights from Louisiana to KnoxvilleDiscover last-minute flight deals from Louisiana to Knoxville. Data last updated March 5, 2026 and is based on user searches.
Discover last-minute flight deals from Louisiana to Knoxville. Data last updated March 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:10 pm
MSY
- TYS
1 stop26h 16m
Multiple Airlines
Mon 3/307:40 am
TYS
- MSY
1 stop25h 39m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
MSY
- TYS
1 stop25h 18m
Multiple Airlines
Mon 3/307:40 am
TYS
- MSY
1 stop25h 39m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:10 pm
MSY
- TYS
1 stop12h 00m
Multiple Airlines
Mon 3/307:40 am
TYS
- MSY
1 stop25h 39m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:10 pm
MSY
- TYS
1 stop24h 41m
Multiple Airlines
Tue 3/313:00 pm
TYS
- MSY
1 stop8h 44m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:00 am
MSY
- TYS
1 stop13h 51m
Multiple Airlines
Mon 3/307:40 am
TYS
- MSY
1 stop25h 39m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:20 am
MSY
- TYS
1 stop12h 14m
Multiple Airlines
Wed 4/84:25 pm
TYS
- MSY
1 stop7h 19m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:10 pm
MSY
- TYS
1 stop14h 26m
Multiple Airlines
Tue 4/72:56 pm
TYS
- MSY
1 stop18h 23m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:18 pm
MSY
- TYS
1 stop27h 21m
Multiple Airlines
Wed 4/84:25 pm
TYS
- MSY
1 stop7h 19m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$217
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
SHV
- TYS
1 stop4h 30m
American Airlines
Wed 4/86:00 am
TYS
- SHV
1 stop5h 03m
American Airlines
Deal found 3/3![American Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:05 pm
BTR
- TYS
1 stop3h 52m
Delta
Wed 4/85:10 pm
TYS
- BTR
1 stop5h 53m
Delta
Deal found 3/2![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:57 pm
BTR
- TYS
1 stop4h 54m
American Airlines
Sat 4/116:00 am
TYS
- BTR
1 stop5h 02m
American Airlines
Deal found 3/2![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:34 am
SHV
- TYS
1 stop6h 30m
American Airlines
Tue 4/146:00 am
TYS
- SHV
1 stop5h 03m
American Airlines
Deal found 2/28![American Airlines logo]()
$286
One-way flights from Louisiana to KnoxvilleSearch for one-way flight options from Louisiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 5, 2026.
Search for one-way flight options from Louisiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
MSY
- TYS
1 stop27h 36m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:10 pm
MSY
- TYS
1 stop24h 41m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:39 pm
MSY
- TYS
1 stop23h 36m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:13 pm
MSY
- TYS
1 stop25h 11m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:10 pm
MSY
- TYS
1 stop18h 00m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:13 pm
MSY
- TYS
1 stop20h 17m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$178
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:05 pm
BTR
- TYS
1 stop3h 52m
Delta
Deal found 3/3![Delta logo]()
$229
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/310:13 am
SHV
- TYS
1 stop4h 24m
American Airlines
Deal found 3/4![American Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:28 am
LFT
- TYS
1 stop6h 03m
American Airlines
Deal found 3/2![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:28 pm
BTR
- TYS
1 stop6h 23m
American Airlines
Deal found 3/3![American Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/39:54 pm
SHV
- TYS
3 stops48h 45m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/133:00 pm
LFT
- TYS
1 stop3h 27m
Delta
Deal found 3/4![Delta logo]()
$465
Find flight deals from Louisiana to Knoxville
Keep the following information in mind while searching for Louisiana to Knoxville flight deals. Data was last updated March 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $194 (Kiwi.com) |
One-way from | $109 (Kiwi.com) |
Popular in | January |
Cheapest in | July |
Average price | $439 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Baton RougeKnoxville
BTR - TYS
BTRTYS
Baton Rouge Ryan
Fri 4/3
7:05 pm-11:57 pm
1 stop3h 52m
Knoxville McGhee Tyson
Wed 4/8
5:10 pm-10:03 pm
1 stop5h 53m
$291
LafayetteKnoxville
LFT - TYS
LFTTYS
Lafayette Regional
Fri 3/20
6:20 pm-11:51 pm
1 stop4h 31m
Knoxville McGhee Tyson
Tue 3/24
5:05 am-9:58 am
1 stop5h 53m
$299
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Fri 3/27
1:05 pm-9:15 pm
2 stops7h 10m
Knoxville McGhee Tyson
Tue 3/31
6:35 am-1:50 pm
2 stops8h 15m
$337
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Fri 4/3
12:40 pm-6:45 pm
1 stop5h 05m
Knoxville McGhee Tyson
Sun 4/5
6:35 am-9:25 am
1 stop3h 50m
$337
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Wed 5/27
10:55 am-8:50 pm
2 stops8h 55m
Knoxville McGhee Tyson
Tue 6/2
7:05 am-2:20 pm
2 stops8h 15m
$347
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Sat 4/25
12:44 pm-10:34 pm
2 stops8h 50m
Knoxville McGhee Tyson
Sat 5/9
9:50 am-2:56 pm
1 stop6h 06m
$352
LafayetteKnoxville
LFT - TYS
LFTTYS
Lafayette Regional
Tue 3/17
5:12 pm-11:57 pm
1 stop5h 45m
Knoxville McGhee Tyson
Sat 3/21
8:45 am-2:19 pm
1 stop6h 34m
$356
ShreveportKnoxville
SHV - TYS
SHVTYS
Shreveport
Sat 8/22
3:35 pm-9:30 pm
1 stop4h 55m
Knoxville McGhee Tyson
Wed 8/26
12:05 pm-5:10 pm
1 stop6h 05m
$359
Baton RougeKnoxville
BTR - TYS
BTRTYS
Baton Rouge Ryan
Sat 4/11
6:08 pm-11:41 pm
1 stop4h 33m
Knoxville McGhee Tyson
Tue 4/14
7:05 am-11:21 am
1 stop5h 16m
$359
New OrleansKnoxville
MSY - TYS
MSYTYS
New Orleans Louis Armstrong
Fri 3/20
1:05 pm-9:15 pm
2 stops7h 10m
Knoxville McGhee Tyson
Mon 3/23
7:25 pm-12:10 am
1 stop5h 45m
$364
Showing 1-10 of 46 resultsSorted by cheapest first
Best time to book a flight from Louisiana to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Louisiana with our price prediction graph.
MSY-TYS
BTR-TYS
SHV-TYS
LFT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisiana to Knoxville
USLA-TYS
MSY-TYS
BTR-TYS
SHV-TYS
LFT-TYS
What is the cheapest month to book a flight from Louisiana to Knoxville?
Currently, April is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $128). Flying from Louisiana to Knoxville in January is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Louisiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Louisiana to Knoxville
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisiana to Knoxville by cabin class
Find flights from Louisiana to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 5, 2026.
Louisiana and Knoxville flights
Browse other Louisiana and Knoxville flight options. Last updated on March 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisiana to Knoxville flights
Consider these flights traveling from Louisiana to Knoxville.
Top 2 airlines flying from Louisiana to Knoxville
Discover the top 2 airlines that operate flights from Louisiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$366 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$216 | Average$364 | FlexibilityNo cancel fee | On-time71% |