$101+ Cheap flights from Louisiana to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Nov 4 — Nov 111
Round-trip
1 adult, Economy
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Find cheap flights from Louisiana to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Louisiana to KnoxvilleExplore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
Explore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:40 am -
1 stop9h 51m
Sun 12/611:00 am -
1 stop8h 53m
Deal found 10/1![Multiple Airlines logo]()
$231
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:50 am -
1 stop7h 10m
Mon 12/145:15 pm -
1 stop6h 05m
Deal found 10/4![Southwest logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:18 pm -
2 stops22h 03m
Tue 10/202:52 pm -
1 stop22h 43m
Deal found 9/30![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:03 pm -
2 stops15h 34m
Sun 12/611:00 am -
1 stop8h 53m
Deal found 10/4![Multiple Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:10 am -
1 stop5h 16m
Wed 10/285:40 am -
1 stop3h 24m
Deal found 10/1![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:45 am -
1 stop8h 55m
Wed 10/285:15 pm -
2 stops5h 50m
Deal found 9/30![Southwest logo]()
$292
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:40 am -
2 stops6h 25m
Sat 11/78:15 am -
2 stops8h 00m
Deal found 10/1![Southwest logo]()
$297
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:24 am -
1 stop4h 08m
Mon 12/145:17 pm -
1 stop6h 43m
Deal found 9/30![American Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:42 pm -
2 stops21h 25m
Mon 11/169:10 am -
1 stop5h 32m
Deal found 10/3![Multiple Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:50 am -
1 stop4h 50m
Tue 10/275:40 am -
1 stop3h 24m
Deal found 9/30![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:44 pm -
1 stop5h 11m
Tue 10/2711:59 am -
1 stop6h 20m
Deal found 9/30![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 pm -
1 stop4h 43m
Sun 11/155:30 am -
1 stop6h 01m
Deal found 10/5![American Airlines logo]()
$339
Best flights from Louisiana to KnoxvilleDiscover carefully curated flight deals from Louisiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
Discover carefully curated flight deals from Louisiana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:30 am -
1 stop6h 10m
Sat 11/73:50 pm -
1 stop5h 05m
Deal found 10/1![Southwest logo]()
$287
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/265:15 am -
1 stop3h 16m
Wed 1/66:00 am -
1 stop5h 19m
Deal found 10/3![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/308:00 am -
1 stop5h 42m
Tue 1/511:53 am -
1 stop5h 19m
Deal found 10/1![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:29 pm -
1 stop6h 16m
Sat 10/246:00 am -
1 stop6h 03m
Deal found 10/3![American Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:44 pm -
1 stop5h 11m
Tue 10/2711:59 am -
1 stop6h 20m
Deal found 9/30![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:00 am -
1 stop7h 10m
Tue 10/273:20 pm -
2 stops7h 45m
Deal found 9/30![Southwest logo]()
$340
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:21 pm -
1 stop4h 36m
Mon 12/147:26 pm -
1 stop5h 41m
Deal found 10/4![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:23 pm -
1 stop5h 09m
Mon 11/95:19 pm -
1 stop4h 56m
Deal found 10/1![American Airlines logo]()
$371
This Southwest deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:25 am -
1 stop5h 25m
Mon 11/167:05 am -
2 stops6h 10m
Deal found 10/3![Southwest logo]()
$372
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:29 pm -
2 stops7h 25m
Sat 10/246:56 am -
1 stop4h 40m
Deal found 10/5![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:44 pm -
1 stop5h 11m
Wed 10/213:45 pm -
1 stop4h 59m
Deal found 10/4![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:40 pm -
1 stop5h 25m
Wed 10/217:15 am -
2 stops7h 50m
Deal found 9/30![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/302:15 pm -
2 stops7h 20m
Tue 1/57:05 am -
2 stops7h 35m
Deal found 10/1![Southwest logo]()
$387
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:06 am -
1 stop7h 26m
Tue 10/271:58 pm -
2 stops9h 50m
Deal found 9/30![American Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:09 pm -
1 stop4h 13m
Sat 10/174:11 pm -
1 stop6h 11m
Deal found 10/4![Delta logo]()
$519
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:30 am -
1 stop7h 00m
Wed 12/3012:40 pm -
1 stop5h 40m
Deal found 10/2![Southwest logo]()
$402
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:29 pm -
1 stop6h 16m
Mon 10/266:00 am -
1 stop4h 28m
Deal found 10/2![American Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:03 am -
1 stop3h 42m
Sun 11/812:06 pm -
1 stop5h 55m
Deal found 10/4![Delta logo]()
$530
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/249:58 am -
1 stop7h 00m
Sun 12/275:30 am -
1 stop4h 58m
Deal found 10/5![American Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:15 am -
2 stops12h 50m
Wed 2/36:30 am -
1 stop8h 04m
Deal found 10/2![United Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:45 am -
1 stop7h 20m
Sun 12/275:30 am -
1 stop5h 39m
Deal found 10/4![American Airlines logo]()
$458
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:50 am -
2 stops9h 55m
Wed 11/117:05 am -
2 stops7h 35m
Deal found 10/1![Southwest logo]()
$477
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:03 pm -
1 stop4h 54m
Fri 10/307:35 pm -
2 stops16h 32m
Deal found 9/30![United Airlines logo]()
$605
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:29 pm -
2 stops7h 25m
Sat 10/174:49 pm -
1 stop6h 09m
Deal found 10/3![American Airlines logo]()
$470
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:28 pm -
1 stop5h 04m
Sat 11/285:30 am -
1 stop5h 35m
Deal found 10/2![American Airlines logo]()
$512
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:13 pm -
1 stop4h 44m
Fri 11/135:40 pm -
2 stops20h 37m
Deal found 10/4![United Airlines logo]()
$699
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:15 pm -
2 stops25h 39m
Sun 11/227:00 am -
1 stop5h 21m
Deal found 10/4![United Airlines logo]()
$732
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:28 pm -
1 stop5h 04m
Sun 11/295:30 am -
1 stop5h 35m
Deal found 10/3![American Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:28 pm -
1 stop5h 04m
Sun 11/295:30 pm -
1 stop4h 53m
Deal found 10/4![American Airlines logo]()
$558
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:07 pm -
1 stop4h 48m
Tue 10/2010:42 am -
3 stops23h 01m
Deal found 9/30![United Airlines logo]()
$780
Last-minute flights from Louisiana to KnoxvilleDiscover last-minute flight deals from Louisiana to Knoxville. Data last updated October 5, 2026 and is based on user searches.
Discover last-minute flight deals from Louisiana to Knoxville. Data last updated October 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:18 pm -
2 stops22h 03m
Tue 10/202:52 pm -
1 stop22h 43m
Deal found 9/30![Multiple Airlines logo]()
$282
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:44 pm -
1 stop5h 11m
Tue 10/2711:59 am -
1 stop6h 20m
Deal found 9/30![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:50 am -
1 stop4h 50m
Tue 10/275:40 am -
1 stop3h 24m
Deal found 9/30![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:10 am -
1 stop5h 16m
Wed 10/285:40 am -
1 stop3h 24m
Deal found 10/1![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:45 am -
1 stop8h 55m
Wed 10/285:15 pm -
2 stops5h 50m
Deal found 9/30![Southwest logo]()
$292
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:50 pm -
1 stop4h 05m
Sat 10/316:00 am -
1 stop6h 48m
Deal found 9/30![American Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:40 am -
2 stops6h 25m
Sat 11/78:15 am -
2 stops8h 00m
Deal found 10/1![Southwest logo]()
$297
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop6h 42m
Wed 11/42:55 pm -
1 stop7h 40m
Deal found 10/2![American Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:40 am -
1 stop11h 25m
Sun 11/86:30 am -
1 stop28h 20m
Deal found 9/30![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:42 pm -
2 stops21h 25m
Mon 11/169:10 am -
1 stop5h 32m
Deal found 10/3![Multiple Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:43 am -
1 stop7h 59m
Mon 11/167:14 pm -
1 stop4h 45m
Deal found 10/2![American Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:39 am -
1 stop7h 26m
Sun 11/225:30 am -
1 stop5h 35m
Deal found 10/1![American Airlines logo]()
$327
One-way flights from Louisiana to KnoxvilleSearch for one-way flight options from Louisiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 5, 2026.
Search for one-way flight options from Louisiana to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:18 pm -
2 stops14h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:08 pm -
2 stops17h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:08 pm -
2 stops41h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:40 am -
1 stop9h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:42 pm -
2 stops17h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:42 pm -
2 stops41h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:08 pm -
2 stops17h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:08 pm -
2 stops41h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:57 pm -
1 stop22h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$127
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:59 pm -
1 stop5h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Delta logo]()
$194
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:30 am -
1 stop7h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$200
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:53 pm -
1 stop3h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Delta logo]()
$202
Find flight deals from Louisiana to Knoxville
Keep the following information in mind while searching for Louisiana to Knoxville flight deals. Data was last updated October 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $231 (Kiwi.com) |
One-way from | $101 (Kiwi.com) |
Popular in | July |
Cheapest in | February |
Average price | $468 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Wed 12/2
6:20 am-11:27 am
1 stop4h 07m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$144
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Sat 11/7
2:25 pm-8:54 pm
1 stop5h 29m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$144
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Tue 11/3
6:25 am-10:45 am
1 stop3h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$154
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Fri 10/30
1:55 pm-9:35 pm
1 stop6h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Fri 12/4
5:20 am-11:27 am
1 stop5h 07m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Wed 12/2
9:30 am-7:50 pm
2 stops9h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$159
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Sat 11/28
5:30 am-11:28 am
1 stop4h 58m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$180
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Thu 11/19
12:44 pm-7:36 pm
1 stop5h 52m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$184
New OrleansKnoxville
MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson
MSYTYS
New Orleans Louis Armstrong
Thu 12/31
3:45 pm-9:44 pm
1 stop4h 59m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$194
Baton RougeKnoxville
BTR Baton Rouge Ryan - TYS Knoxville McGhee Tyson
BTRTYS
Baton Rouge Ryan
Tue 12/1
3:59 pm-10:17 pm
1 stop5h 18m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$194
Showing 1-10 of 52 resultsSorted by cheapest first
Best time to book a flight from Louisiana to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Louisiana with our price prediction graph.
MSY-TYS
BTR-TYS
LFT-TYS
SHV-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisiana to Knoxville
USLA-TYS
MSY-TYS
BTR-TYS
LFT-TYS
SHV-TYS
What is the cheapest month to book a flight from Louisiana to Knoxville?
Currently, February is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $364). Flying from Louisiana to Knoxville in March is currently the most expensive (average of $599). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from LA to TYS?
Find hourly flight availability from Louisiana to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 5, 2026.
When flying from Louisiana to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Louisiana to Knoxville?
Airfare is below average for this route at the moment.
Louisiana to Knoxville flights typically cost between $343 and $683 in December.The cheapest round-trip price found within the last 5 days was $231 on Multiple Airlines (Dec 3-Dec 6).
Related info for your journey
Find useful and relevant information for your journey from Louisiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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Alternative routes for Louisiana to Knoxville
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisiana to Knoxville by cabin class
Find flights from Louisiana to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 5, 2026.
Louisiana and Knoxville flights
Browse other Louisiana and Knoxville flight options. Last updated on October 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisiana to Knoxville flights
Consider these flights traveling from Louisiana to Knoxville.
Top 3 airlines flying from Louisiana to Knoxville
Discover the top 3 airlines that operate flights from Louisiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$263 | Average$421 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$294 | Average$438 | FlexibilityNo cancel fee | On-time63% |