Knoxville

$128+ Cheap flights from Louisiana to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — TYS
Jul 7 — Jul 141
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Cheap flight deals from Louisiana to Knoxville

Cheapest flights from Louisiana to Knoxville
Explore the most affordable flight options available from Louisiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:26 pm
SHV
-
TYS
1 stop25h 37m
Allegiant Air
Thu 8/132:49 pm
TYS
-
SHV
1 stop24h 47m
Allegiant Air
Deal found 6/6$260
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/314:35 pm
MSY
-
TYS
1 stop5h 58m
Multiple Airlines
Mon 8/37:20 pm
TYS
-
MSY
1 stop17h 31m
Multiple Airlines
Deal found 6/2$260
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
LFT
-
TYS
1 stop6h 16m
Delta
Tue 7/2111:57 am
TYS
-
LFT
1 stop3h 37m
Delta
Deal found 6/2$261
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:00 am
MSY
-
TYS
1 stop14h 33m
Multiple Airlines
Mon 7/137:20 pm
TYS
-
MSY
1 stop17h 31m
Multiple Airlines
Deal found 6/2$270
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:50 pm
MSY
-
TYS
1 stop21h 28m
Multiple Airlines
Sun 8/161:33 pm
TYS
-
MSY
1 stop8h 22m
Multiple Airlines
Deal found 6/4$276
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/244:35 pm
MSY
-
TYS
1 stop5h 58m
Multiple Airlines
Mon 7/2712:40 pm
TYS
-
MSY
2 stops28h 32m
Multiple Airlines
Deal found 6/5$280
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:35 pm
MSY
-
TYS
1 stop5h 58m
Multiple Airlines
Tue 7/214:20 pm
TYS
-
MSY
1 stop20h 31m
Multiple Airlines
Deal found 6/3$287
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
BTR
-
TYS
1 stop4h 06m
Delta
Tue 10/133:55 pm
TYS
-
BTR
1 stop3h 35m
Delta
Deal found 6/4$291
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/263:44 pm
MSY
-
TYS
1 stop6h 50m
Multiple Airlines
Mon 6/2910:03 pm
TYS
-
MSY
2 stops19h 23m
Multiple Airlines
Deal found 6/3$293
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:39 am
MSY
-
TYS
1 stop13h 45m
Multiple Airlines
Mon 7/1312:53 pm
TYS
-
MSY
2 stops28h 19m
Multiple Airlines
Deal found 6/3$294
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:03 pm
LFT
-
TYS
1 stop5h 51m
Delta
Fri 7/1011:57 am
TYS
-
LFT
1 stop3h 37m
Delta
Deal found 6/4$295
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:00 am
SHV
-
TYS
1 stop6h 05m
Delta
Sat 10/175:30 am
TYS
-
SHV
1 stop5h 41m
Delta
Deal found 6/2$295

Find flight deals from Louisiana to Knoxville

Keep the following information in mind while searching for Louisiana to Knoxville flight deals. Data was last updated June 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$260
(Kiwi.com)

One-way from

$128
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$343
Provider with most accurate pricing for New Orleans Louis Armstrong-Knoxville McGhee Tyson flight deals.
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Knoxville McGhee Tyson flights.
From Louisiana to Knoxville McGhee Tyson
One-way flight from Louisiana to Knoxville McGhee Tyson
Highest demand for flights based on searches. 14% potential increase in price ($66 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from Louisiana to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 7/14

5:03 pm-11:52 pm

1 stop5h 49m

Knoxville McGhee Tyson

Tue 7/21

5:40 am-10:52 am

1 stop6h 12m

$261

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 7/14

5:36 pm-11:51 pm

1 stop5h 15m

Knoxville McGhee Tyson

Tue 7/21

5:37 am-10:22 am

1 stop5h 45m

$261

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Tue 7/21

6:16 pm-11:51 pm

1 stop4h 35m

Knoxville McGhee Tyson

Tue 7/28

4:07 pm-9:30 pm

1 stop6h 23m

$291

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Tue 10/13

8:00 am-3:05 pm

1 stop6h 05m

Knoxville McGhee Tyson

Sat 10/17

5:30 am-10:11 am

1 stop5h 41m

$295

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Wed 7/29

2:36 pm-11:51 pm

2 stops8h 15m

Knoxville McGhee Tyson

Sat 8/1

5:37 am-9:34 am

1 stop4h 57m

$300

ShreveportKnoxville

SHV - TYS

SHVTYS

Shreveport

Fri 10/2

12:53 pm-8:07 pm

1 stop6h 14m

Knoxville McGhee Tyson

Fri 10/9

8:47 am-12:24 pm

1 stop4h 37m

$309

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Thu 7/2

5:03 pm-9:49 pm

1 stop3h 46m

Knoxville McGhee Tyson

Wed 7/8

5:40 am-10:52 am

1 stop6h 12m

$310

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Wed 11/18

5:15 am-11:23 am

1 stop5h 08m

Knoxville McGhee Tyson

Sun 11/22

5:05 am-8:32 am

1 stop4h 27m

$317

Baton RougeKnoxville

BTR - TYS

BTRTYS

Baton Rouge Ryan

Fri 7/31

6:16 pm-11:51 pm

1 stop4h 35m

Knoxville McGhee Tyson

Sat 8/1

5:37 am-11:14 am

1 stop6h 37m

$323

New OrleansKnoxville

MSY - TYS

MSYTYS

New Orleans Louis Armstrong

Fri 7/24

12:36 pm-11:33 pm

1 stop9h 57m

Knoxville McGhee Tyson

Sun 7/26

3:38 pm-11:51 am

2 stops21h 13m

$326

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/5

Showing 1-10 of 54 resultsSorted by cheapest first
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Best time to book a flight from Louisiana to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Knoxville

What is the cheapest month to book a flight from Louisiana to Knoxville?

Currently, November is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $218). Flying from Louisiana to Knoxville in May is currently the most expensive (average of $298). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Louisiana to Knoxville?

How far ahead should I book a flight from Louisiana to Knoxville?

To ensure you get the cheapest price possible for a flight from Louisiana to Knoxville, you should look to book at least 28 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Knoxville from Louisiana?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Louisiana to Knoxville. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Louisiana to Knoxville?

    For as low as $261, Delta can have you in Knoxville from Louisiana in 5h 15m. The distance from Louisiana to Knoxville is about 603 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Louisiana to Knoxville?

  • Can I find deals for flights from Louisiana to Knoxville that include hotel bookings?

    Yes. In addition to deals on Louisiana to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Knoxville.

  • Can I find deals for business class flights from Louisiana to Knoxville?

    Yes. Cheapflights offers flight deals from Louisiana to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Knoxville?

    Currently, November is the cheapest month in which you can book a flight from Louisiana to Knoxville (average of $218). Flying from Louisiana to Knoxville in May is currently the most expensive (average of $298). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

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Alternative routes for Louisiana to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Louisiana to Knoxville

Discover the top 3 airlines that operate flights from Louisiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$411FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$370FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$294Average$458FlexibilityNo cancel feeOn-time63%

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