$121+ Cheap flights from LaGuardia, NY (LGA) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — TYS
Oct 27 — Nov 31
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from LaGuardia to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from New York LaGuardia to Knoxville McGhee Tyson are usually found in February or July, booked 67 days in advance, depart on a Saturday or Wednesday and return on a Saturday
Cheap flight deals from LaGuardia to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from LaGuardia to KnoxvilleExplore the most affordable flight options available from LaGuardia to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2026.
Explore the most affordable flight options available from LaGuardia to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2026.
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:40 am -
2 stops9h 30m
Tue 11/35:15 pm -
1 stop5h 20m
Deal found 9/26![Southwest logo]()
$322
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:00 am -
1 stop5h 20m
Wed 11/115:15 pm -
1 stop5h 20m
Deal found 9/27![Southwest logo]()
$328
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:35 am -
Nonstop2h 21m
Mon 10/266:00 am -
Nonstop1h 59m
Deal found 9/23![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:15 am -
1 stop5h 58m
Sat 11/146:45 am -
2 stops7h 30m
Deal found 9/23![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:35 am -
Nonstop2h 21m
Wed 10/285:40 am -
1 stop6h 02m
Deal found 9/22![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:20 am -
2 stops10h 15m
Wed 11/115:15 pm -
1 stop5h 20m
Deal found 9/25![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:40 pm -
1 stop6h 05m
Tue 11/105:15 pm -
1 stop5h 20m
Deal found 9/22![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:50 pm -
Nonstop2h 19m
Sat 10/311:40 pm -
Nonstop2h 06m
Deal found 9/24![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:15 am -
2 stops9h 25m
Sat 10/242:55 pm -
1 stop6h 15m
Deal found 9/22![Southwest logo]()
$363
Best flights from LaGuardia to KnoxvilleDiscover carefully curated flight deals from LaGuardia to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 27, 2026.
Discover carefully curated flight deals from LaGuardia to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 27, 2026.
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:50 pm -
Nonstop2h 19m
Wed 10/285:15 pm -
Nonstop2h 06m
Deal found 9/22![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:15 am -
2 stops9h 25m
Wed 10/287:15 am -
2 stops8h 45m
Deal found 9/23![Southwest logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
2 stops7h 14m
Wed 10/2810:45 am -
1 stop5h 38m
Deal found 9/25![United Airlines logo]()
$494
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:50 pm -
Nonstop2h 19m
Sun 11/16:00 am -
Nonstop1h 59m
Deal found 9/24![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:48 pm -
Nonstop2h 27m
Mon 1/186:10 am -
Nonstop2h 01m
Deal found 9/24![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:00 am -
Nonstop2h 24m
Sat 12/1211:49 am -
1 stop5h 46m
Deal found 9/26![Delta logo]()
$439
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1812:00 pm -
2 stops9h 40m
Tue 12/227:00 am -
2 stops10h 55m
Deal found 9/25![Southwest logo]()
$593
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:45 am -
Nonstop2h 17m
Mon 10/198:35 am -
1 stop6h 04m
Deal found 9/23![Delta logo]()
$449
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:00 pm -
1 stop6h 57m
Sat 10/101:40 pm -
Nonstop2h 06m
Deal found 9/25![Delta logo]()
$505
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:52 am -
Nonstop2h 12m
Mon 10/55:15 pm -
Nonstop2h 06m
Deal found 9/26![Delta logo]()
$600
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/219:09 am -
Nonstop2h 24m
Mon 12/287:25 am -
1 stop4h 23m
Deal found 9/24![Delta logo]()
$629
Last-minute flights from LaGuardia to KnoxvilleDiscover last-minute flight deals from LaGuardia to Knoxville. Data last updated September 27, 2026 and is based on user searches.
Discover last-minute flight deals from LaGuardia to Knoxville. Data last updated September 27, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:15 am -
2 stops9h 25m
Sat 10/242:55 pm -
1 stop6h 15m
Deal found 9/22![Southwest logo]()
$363
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:15 am -
2 stops9h 25m
Tue 10/273:20 pm -
1 stop7h 05m
Deal found 9/22![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:35 am -
Nonstop2h 21m
Mon 10/266:00 am -
Nonstop1h 59m
Deal found 9/23![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:35 am -
Nonstop2h 21m
Tue 10/272:38 pm -
1 stop7h 04m
Deal found 9/22![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:40 am -
2 stops9h 30m
Tue 11/35:15 pm -
1 stop5h 20m
Deal found 9/26![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:50 pm -
Nonstop2h 19m
Sat 10/311:40 pm -
Nonstop2h 06m
Deal found 9/24![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:40 pm -
1 stop6h 05m
Tue 11/105:15 pm -
1 stop5h 20m
Deal found 9/22![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 pm -
1 stop4h 32m
Mon 11/25:15 pm -
Nonstop2h 06m
Deal found 9/25![Delta logo]()
$369
One-way flights from LaGuardia to KnoxvilleSearch for one-way flight options from LaGuardia to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 27, 2026.
Search for one-way flight options from LaGuardia to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:30 pm -
2 stops41h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:29 am -
2 stops12h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:30 pm -
2 stops27h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
2 stops15h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$149
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:00 pm -
1 stop7h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Southwest logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:30 pm -
2 stops42h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$160
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:15 am -
2 stops9h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Southwest logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:30 am -
2 stops15h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$172
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:00 am -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Southwest logo]()
$180
Find flight deals from LaGuardia to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from LaGuardia (LGA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $317 (Southwest) |
One-way from | $121 (Kiwi.com) |
Popular in | December |
Cheapest in | February |
Average price | $529 |
Good round-trip deal | $369 or less |
Good one-way deal | $423 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from LaGuardia to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 27, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Mon 10/19
12:30 pm-10:45 pm
2 stops10h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$229
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Tue 10/13
10:40 am-8:10 pm
2 stops9h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$259
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Fri 10/23
6:50 pm-9:09 pm
Nonstop2h 19m
Knoxville McGhee Tyson
Wed 10/28
5:15 pm-7:21 pm
Nonstop2h 06m
$339
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Fri 11/27
3:29 pm-8:54 pm
1 stop5h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$344
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Thu 12/10
6:45 pm-9:06 pm
Nonstop2h 21m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$344
Quickest round-trip
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Tue 11/3
8:45 am-11:02 am
Nonstop2h 17m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$344
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Fri 11/20
2:30 pm-8:54 pm
1 stop6h 24m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$344
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Thu 12/24
3:48 pm-6:15 pm
Nonstop2h 27m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$354
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Tue 10/27
7:37 pm-11:59 pm
1 stop4h 22m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$354
New YorkKnoxville
LGA New York LaGuardia - TYS Knoxville McGhee Tyson
LGATYS
New York LaGuardia
Thu 11/5
6:50 pm-9:09 pm
Nonstop2h 19m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$354
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from LaGuardia to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from LaGuardia to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on New York LaGuardia Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on New York LaGuardia Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from New York LaGuardia Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on New York LaGuardia Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New York LaGuardia Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from LaGuardia to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from LaGuardia with our price prediction graph.
LGA-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from New York LaGuardia Airport to Knoxville
Prices
Airlines
How far ahead should I book a flight from New York LaGuardia Airport to Knoxville?
The price you pay for your flight from New York LaGuardia Airport to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 66 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from New York LaGuardia Airport to Knoxville?
Currently, February is the cheapest month in which you can book a flight from New York LaGuardia Airport to Knoxville (average of $469). Flying from New York LaGuardia Airport to Knoxville in December is currently the most expensive (average of $739). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from LGA to TYS?
Find hourly flight availability from LaGuardia to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 27, 2026.
One of the essential ways to save on airfare from New York LaGuardia Airport to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 14% on airfare.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 27, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from New York LaGuardia Airport to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from LaGuardia to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from LaGuardia
Popular flights
Alternative routes for LaGuardia to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from LaGuardia to Knoxville by cabin class
Find flights from LaGuardia to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 27, 2026.
LaGuardia and Knoxville flights
Browse other LaGuardia and Knoxville flight options. Last updated on September 27, 2026.
Other flights from LaGuardia
Browse through other flights departing from LaGuardia. Flights are based on user searches made on Cheapflights and were last updated on September 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from LaGuardia to Knoxville
Discover the top 3 airlines that operate flights from LaGuardia to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$234 | Average$526 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$284 | Average$463 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$359 | Average$545 | FlexibilityNo cancel fee | On-timeN/A |