What are the cheapest airlines flying from Jacksonville, North Carolina to Knoxville round-trip?

Delta, at $251, was found to be the cheapest airline from Jacksonville, North Carolina to Knoxville. An alternate airline flying to your destination would be American Airlines.

What is the cheapest day to fly from Jacksonville, North Carolina to Knoxville?

Travelers seeking maximum savings on their Jacksonville, North Carolina to Knoxville flight should consider departing on Saturday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What is the cheapest day to fly round-trip from Jacksonville, North Carolina to Knoxville?

Departing on a Friday is a good option for securing a great price. You can expect to save up to 7% when planning your travel around this day of the week.

What is the cheapest time of day to fly from OAJ to TYS?

When flying from Jacksonville, North Carolina to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 45% versus a flight in the afternoon.

Can I find deals for flights from Jacksonville to Knoxville that include hotel bookings?

Yes. In addition to deals on Jacksonville to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Jacksonville to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Knoxville.

Can I find deals for business class flights from Jacksonville to Knoxville?

Yes. Cheapflights offers flight deals from Jacksonville to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$251+ Flights from Jacksonville, NC to Knoxville

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Jacksonville to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Jacksonville to Knoxville

Round-trip from	$251 (Delta)

From Jacksonville Albert J Ellis to Knoxville McGhee Tyson

Search Deals

Find flight deals from Jacksonville to Knoxville

Cheapest flights from Jacksonville to Knoxville
Explore the most affordable flight options available from Jacksonville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 28, 2025.

sáb. 8/235:55 amOAJ - TYS

1 stop4h 32mDelta

mar. 8/2611:54 amTYS - OAJ

1 stop3h 53mDelta

Deal found 7/27

$251

sáb. 8/237:00 amOAJ - TYS

1 stop5h 17mAmerican Airlines

mar. 8/267:00 amTYS - OAJ

2 stops9h 41mAmerican Airlines

Deal found 7/26

$316

Best flights from Jacksonville to Knoxville
Discover carefully curated flight deals from Jacksonville to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated julio 28, 2025.

sáb. 8/235:55 amOAJ - TYS

1 stop4h 32mDelta

mar. 8/2611:54 amTYS - OAJ

1 stop3h 53mDelta

Deal found 7/27

$251

sáb. 8/237:00 amOAJ - TYS

1 stop5h 17mAmerican Airlines

mar. 8/267:00 amTYS - OAJ

2 stops9h 41mAmerican Airlines

Deal found 7/26

$316

Last-minute flights from Jacksonville to Knoxville
Discover last-minute flight deals from Jacksonville to Knoxville. Data last updated julio 28, 2025 and is based on user searches.

sáb. 8/235:55 amOAJ - TYS

1 stop4h 32mDelta

mar. 8/2611:54 amTYS - OAJ

1 stop3h 53mDelta

Deal found 7/27

$251

sáb. 8/237:00 amOAJ - TYS

1 stop5h 17mAmerican Airlines

mar. 8/267:00 amTYS - OAJ

2 stops9h 41mAmerican Airlines

Deal found 7/26

$316

Cheapflights Fare Finder

Use the filters below to find and compare flights from Jacksonville to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonvilleKnoxville

OAJ - TYS

OAJTYS

Jacksonville Albert J Ellis

sáb. 8/23

5:55 am-10:27 am

1 stop4h 32m

Knoxville McGhee Tyson

mar. 8/26

11:54 am-3:47 pm

1 stop3h 53m

$251

JacksonvilleKnoxville

OAJ - TYS

OAJTYS

Jacksonville Albert J Ellis

sáb. 8/23

7:00 am-12:17 pm

1 stop5h 17m

Knoxville McGhee Tyson

mar. 8/26

7:00 am-4:41 pm

2 stops9h 41m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Jacksonville to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Jacksonville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Knoxville

What is the cheapest month to book a flight from Jacksonville, North Carolina to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Jacksonville, North Carolina to Knoxville (average of $295). Flying from Jacksonville, North Carolina to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Peruse reviews from past customers who have flown with Delta and American Airlines from Jacksonville to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,971 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,971 reviews

Delta

8.0

Very good

7,971 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,971 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Jacksonville, North Carolina to Knoxville round-trip?
Delta, at $251, was found to be the cheapest airline from Jacksonville, North Carolina to Knoxville. An alternate airline flying to your destination would be American Airlines.
Can I find deals for flights from Jacksonville to Knoxville that include hotel bookings?
Yes. In addition to deals on Jacksonville to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Jacksonville to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Knoxville.
Can I find deals for business class flights from Jacksonville to Knoxville?
Yes. Cheapflights offers flight deals from Jacksonville to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Jacksonville, North Carolina to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Jacksonville, North Carolina to Knoxville (average of $295). Flying from Jacksonville, North Carolina to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Corbin

Cherokee

Alcoa

Oak Ridge

Murphy

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Jacksonville to Knoxville

Raleigh to Nashville flights

Charlotte to Nashville flights

Norfolk to Nashville flights

Myrtle Beach to Nashville flights

Greensboro to Nashville flights

Charlotte to Memphis flights

Raleigh to Memphis flights

Norfolk to Knoxville flights

Raleigh to Chattanooga flights

Norfolk to Memphis flights

Fayetteville to Nashville flights

Charlotte to Knoxville flights

Asheville to Nashville flights

Raleigh to Knoxville flights

Blountville to Nashville flights

Greensboro to Memphis flights

Wilmington to Nashville flights

Knoxville to Memphis flights

Knoxville to Nashville flights

Asheville to Memphis flights

Norfolk to Chattanooga flights

Greensboro to Chattanooga flights

Wilmington to Memphis flights

Charlotte to Chattanooga flights

Myrtle Beach to Knoxville flights

Blountville to Memphis flights

New Bern to Nashville flights

Wilmington to Knoxville flights

Myrtle Beach to Memphis flights

Jacksonville to Nashville flights

New Bern to Chattanooga flights

Fayetteville to Memphis flights

New Bern to Blountville flights

Greenville to Knoxville flights

Raleigh to Blountville flights

Greenville to Nashville flights

New Bern to Knoxville flights

Greenville to Memphis flights

New Bern to Memphis flights

Jacksonville to Memphis flights

Blountville to Knoxville flights

Jacksonville to Blountville flights

Knoxville to Chattanooga flights

Complete your trip

Knoxville car rentals

Knoxville McGhee Tyson Airport car rentals

Asheville Regional Airport car rentals

Chattanooga Lovell Field Airport car rentals

Blountville Tri Cities TN/VA Airport car rentals

Nashville car rentals

Memphis car rentals

Chattanooga car rentals

Kingsport car rentals

Jackson car rentals

Other flights to Knoxville

Top airline flying from Jacksonville to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$250	Average$308	FlexibilityNo cancel fee	On-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$251+ Cheap flights from Jacksonville, NC to Knoxville (OAJ - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Jacksonville to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Jacksonville to Knoxville

Round-trip from

Find flight deals from Jacksonville to Knoxville

Cheapest flights from Jacksonville to KnoxvilleExplore the most affordable flight options available from Jacksonville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 28, 2025.

Explore the most affordable flight options available from Jacksonville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Jacksonville to Knoxville that are best for you.

Best time to book a flight from Jacksonville to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Jacksonville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Knoxville

What is the cheapest month to book a flight from Jacksonville, North Carolina to Knoxville?

Reviews of airlines servicing Knoxville

Peruse reviews from past customers who have flown with Delta and American Airlines from Jacksonville to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Jacksonville, North Carolina to Knoxville round-trip?

Can I find deals for flights from Jacksonville to Knoxville that include hotel bookings?

How can I find direct flights from Jacksonville to Knoxville?

Can I find deals for business class flights from Jacksonville to Knoxville?

What is the cheapest month to book a flight from Jacksonville, North Carolina to Knoxville?

Traveling to a place near Knoxville?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Jacksonville to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Jacksonville to Knoxville

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Jacksonville to Knoxville
Explore the most affordable flight options available from Jacksonville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 28, 2025.