HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$159+ Cheap flights from Jackson, MS to Knoxville (JAN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Jackson to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Jackson to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Jackson (JAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$387
(American Airlines)

One-way from

$159
(American Airlines)

Popular in

August

Cheapest in

July

Average price

$382
From Jackson-Evers Intl to Knoxville McGhee Tyson
Search Deals
One-way flight from Jackson-Evers Intl to Knoxville McGhee Tyson
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Jackson to Knoxville

Cheapest flights from Jackson to Knoxville
Explore the most affordable flight options available from Jackson to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/241:38 pmJAN - TYS
1 stop6h 12mAmerican Airlines
Sat 9/275:05 amTYS - JAN
1 stop5h 51mAmerican Airlines
Deal found 9/9$387
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2011:30 amJAN - TYS
1 stop4h 19mAmerican Airlines
Sat 9/275:05 amTYS - JAN
1 stop5h 51mAmerican Airlines
Deal found 9/10$391
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:18 pmJAN - TYS
1 stop3h 28mDelta
Fri 10/313:56 pmTYS - JAN
1 stop3h 37mDelta
Deal found 9/10$399
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:18 pmJAN - TYS
1 stop3h 28mDelta
Fri 10/313:56 pmTYS - JAN
1 stop3h 37mDelta
Deal found 9/10$413
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/184:28 pmJAN - TYS
1 stop6h 25mAmerican Airlines
Sun 10/198:37 pmTYS - JAN
1 stop4h 35mAmerican Airlines
Deal found 9/10$480
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:16 pmJAN - TYS
1 stop4h 36mAmerican Airlines
Tue 12/307:00 amTYS - JAN
1 stop6h 31mAmerican Airlines
Deal found 9/9$519
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/115:10 amJAN - TYS
1 stop6h 17mAmerican Airlines
Fri 10/178:37 pmTYS - JAN
1 stop4h 35mAmerican Airlines
Deal found 9/10$523
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:43 pmJAN - TYS
1 stop4h 10mAmerican Airlines
Fri 10/178:37 pmTYS - JAN
1 stop4h 35mAmerican Airlines
Deal found 9/10$571
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:05 pmJAN - TYS
1 stop5h 38mUnited Airlines
Sun 10/194:40 pmTYS - JAN
2 stops30h 18mUnited Airlines
Deal found 9/10$574
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1410:59 amJAN - TYS
1 stop4h 04mAmerican Airlines
Tue 9/168:23 amTYS - JAN
1 stop4h 15mAmerican Airlines
Deal found 9/10$577
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/112:05 pmJAN - TYS
2 stops22h 20mUnited Airlines
Fri 10/177:15 amTYS - JAN
1 stop15h 43mUnited Airlines
Deal found 9/10$582
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:57 pmJAN - TYS
1 stop8h 47mUnited Airlines
Sun 11/167:00 amTYS - JAN
1 stop5h 22mUnited Airlines
Deal found 9/9$583

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jackson to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Jackson to Knoxville that are best for you.

Fly from

Jackson

Fly to

Knoxville

Route

Depart

Return

Price

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Fri 9/26

7:19 pm-11:44 pm

1 stop3h 25m

Knoxville McGhee Tyson

Sun 9/28

5:45 am-10:45 am

1 stop6h 00m

$387

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Wed 9/24

1:38 pm-8:50 pm

1 stop6h 12m

Knoxville McGhee Tyson

Sat 9/27

5:05 am-9:56 am

1 stop5h 51m

$387

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 9/20

3:35 pm-11:03 pm

1 stop6h 28m

Knoxville McGhee Tyson

Sat 9/27

5:05 am-9:56 am

1 stop5h 51m

$391

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sun 10/26

7:18 pm-11:46 pm

1 stop3h 28m

Knoxville McGhee Tyson

Fri 10/31

3:56 pm-6:33 pm

1 stop3h 37m

$399

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sun 10/19

7:18 pm-11:46 pm

1 stop3h 28m

Knoxville McGhee Tyson

Fri 10/31

3:56 pm-6:33 pm

1 stop3h 37m

$413

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 10/11

5:10 am-12:27 pm

1 stop6h 17m

Knoxville McGhee Tyson

Fri 10/17

8:37 pm-12:12 am

1 stop4h 35m

$523

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Fri 10/10

6:43 pm-11:53 pm

1 stop4h 10m

Knoxville McGhee Tyson

Fri 10/17

8:37 pm-12:12 am

1 stop4h 35m

$571

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 10/18

5:05 pm-11:43 pm

1 stop5h 38m

Knoxville McGhee Tyson

Sun 10/19

4:40 pm-9:58 pm

2 stops30h 18m

$574

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sun 9/14

10:59 am-4:03 pm

1 stop4h 04m

Knoxville McGhee Tyson

Tue 9/16

8:23 am-11:38 am

1 stop4h 15m

$577

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 10/11

2:05 pm-1:25 pm

2 stops22h 20m

Knoxville McGhee Tyson

Fri 10/17

7:15 am-9:58 pm

1 stop15h 43m

$582

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/8

Showing 1-10 of 15 results
1
2

Best time to book a flight from Jackson to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Jackson with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jackson to Knoxville

What is the cheapest month to book a flight from Jackson, Mississippi to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Jackson, Mississippi to Knoxville (average of $294). Flying from Jackson, Mississippi to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAN to TYS?

Find hourly flight availability from Jackson to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Jackson, Mississippi to Knoxville in the afternoon. Doing so could potentially save you 28% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Jackson, Mississippi to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta and American Airlines from Jackson to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Jackson to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jackson, Mississippi to Knoxville?

    Delta and American Airlines can get you from Jackson, Mississippi to Knoxville in just under 3h 25m. Your travel time can differ by up to 2h 47m. The distance from Jackson, Mississippi to Knoxville is about 424 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Jackson, Mississippi to Knoxville round-trip?

    According to our current data, Delta ($228), and American Airlines ($278) offers the cheapest pricing from Jackson, Mississippi to Knoxville. Delta is currently priced 53% below the average price you’ll pay for this route.

  • Can I find deals for flights from Jackson to Knoxville that include hotel bookings?

    Yes. In addition to deals on Jackson to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jackson to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jackson to Knoxville.

  • Can I find deals for business class flights from Jackson to Knoxville?

    Yes. Cheapflights offers flight deals from Jackson to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jackson, Mississippi to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Jackson, Mississippi to Knoxville (average of $294). Flying from Jackson, Mississippi to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Jackson to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Baton Rouge to Nashville flights
Memphis to Nashville flights
Memphis to Knoxville flights
Gulfport to Knoxville flights
Jackson to Nashville flights
Mobile to Nashville flights
Gulfport to Nashville flights
Baton Rouge to Knoxville flights
Memphis to Chattanooga flights
Baton Rouge to Memphis flights
Baton Rouge to Chattanooga flights
Mobile to Memphis flights
Gulfport to Chattanooga flights
Mobile to Chattanooga flights
Alexandria to Nashville flights
Mobile to Blountville flights
Laurel to Nashville flights
Jackson to Chattanooga flights
Jackson to Memphis flights
Columbus to Memphis flights
Meridian to Nashville flights
Baton Rouge to Blountville flights
Alexandria to Chattanooga flights
Jackson to Blountville flights

Top 2 airlines flying from Jackson to Knoxville

Discover the top 2 airlines that operate flights from Jackson to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$445FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$278Average$464FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.