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$107+ Cheap flights from Harrisburg to Knoxville (MDT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — TYS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Harrisburg to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$218
(Mytrip)

One-way from

$107
(Mytrip)

Popular in

February

Cheapest in

May

Average price

$429
From Harrisburg to Knoxville McGhee Tyson
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One-way flight from Harrisburg to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 28% potential increase in price ($165 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Harrisburg to Knoxville

Cheapest flights from Harrisburg to Knoxville
Explore the most affordable flight options available from Harrisburg to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/259:13 pmMDT - TYS
1 stop22h 11mAllegiant Air
Wed 8/2712:44 pmTYS - MDT
1 stop22h 36mAllegiant Air
Deal found 6/10$218
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/111:00 pmMDT - TYS
1 stop4h 33mAmerican Airlines
Fri 7/187:52 pmTYS - MDT
1 stop3h 40mAmerican Airlines
Deal found 6/11$229
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/277:59 pmMDT - TYS
1 stop4h 00mUnited Airlines
Tue 7/15:45 amTYS - MDT
1 stop4h 00mUnited Airlines
Deal found 6/12$239
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/259:13 pmMDT - TYS
1 stop22h 11mMultiple Airlines
Wed 8/277:15 amTYS - MDT
2 stops32h 48mMultiple Airlines
Deal found 6/10$278
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/212:33 pmMDT - TYS
2 stops9h 38mDelta
Sat 7/54:11 pmTYS - MDT
2 stops6h 49mDelta
Deal found 6/9$828

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Harrisburg to Knoxville that are best for you.

Fly from

Harrisburg

Fly to

Knoxville

Route

Depart

Return

Price

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Mon 8/25

9:13 pm-7:24 pm

1 stop22h 11m

Knoxville McGhee Tyson

Wed 8/27

12:44 pm-11:20 am

1 stop22h 36m

$218

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Fri 7/11

1:00 pm-5:33 pm

1 stop4h 33m

Knoxville McGhee Tyson

Fri 7/18

7:52 pm-11:32 pm

1 stop3h 40m

$229

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Fri 6/27

7:59 pm-11:59 pm

1 stop4h 00m

Knoxville McGhee Tyson

Tue 7/1

5:45 am-9:45 am

1 stop4h 00m

$239

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Mon 8/25

9:13 pm-7:24 pm

1 stop22h 11m

Knoxville McGhee Tyson

Wed 8/27

7:15 am-4:03 pm

2 stops32h 48m

$278

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Wed 7/2

12:33 pm-10:11 pm

2 stops9h 38m

Knoxville McGhee Tyson

Sat 7/5

4:11 pm-11:00 pm

2 stops6h 49m

$828

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Sun 7/13

9:19 pm-9:20 pm

1 stop24h 01m

$107

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Thu 9/4

6:00 am-10:42 am

1 stop4h 42m

$155

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Thu 9/4

2:24 pm-10:35 pm

2 stops8h 11m

$190

HarrisburgKnoxville

MDT - TYS

MDTTYS

Harrisburg

Thu 8/14

4:37 pm-4:45 pm

3 stops24h 08m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Harrisburg to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Knoxville

What is the cheapest month to book a flight from Harrisburg to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to Knoxville (average of $296). Flying from Harrisburg to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to TYS?

Find hourly flight availability from Harrisburg to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Harrisburg to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 28% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Harrisburg to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Harrisburg to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Harrisburg to Knoxville flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
See what other customers who have flown with Delta, United Airlines and Allegiant Air from Harrisburg to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.3
Good
725 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Harrisburg to Knoxville round-trip?

    According to our current data, Allegiant Air ($218), American Airlines ($229), and United Airlines ($239) offers the cheapest pricing from Harrisburg to Knoxville. Allegiant Air is 47% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Harrisburg to Knoxville one-way?

    $107 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $155 and $190, respectively.

  • Can I find deals for flights from Harrisburg to Knoxville that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Knoxville.

  • Can I find deals for business class flights from Harrisburg to Knoxville?

    Yes. Cheapflights offers flight deals from Harrisburg to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Harrisburg to Knoxville (average of $296). Flying from Harrisburg to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 2 airlines flying from Harrisburg to Knoxville

Discover the top 2 airlines that operate flights from Harrisburg to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$313FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$402FlexibilityNo cancel feeOn-time71%

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