HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$397+ Cheap flights from Erie to Knoxville (ERI - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
ERI — TYS
Dec 18 — Dec 251
Thu 12/18
Thu 12/25
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Erie to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Erie to Knoxville

Cheapest flights from Erie to Knoxville
Explore the most affordable flight options available from Erie to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 18, 2025.

This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:21 amERI - TYS
1 stop5h 10mAmerican Airlines
Sat 11/296:30 amTYS - ERI
1 stop4h 16mAmerican Airlines
Deal found 11/17$430
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:00 amERI - TYS
1 stop4h 19mAmerican Airlines
Sat 11/296:30 amTYS - ERI
1 stop4h 16mAmerican Airlines
Deal found 11/17$473
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:21 amERI - TYS
1 stop7h 31mAmerican Airlines
Fri 11/286:30 amTYS - ERI
1 stop4h 16mAmerican Airlines
Deal found 11/17$475
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2311:16 amERI - TYS
1 stop6h 45mAmerican Airlines
Fri 11/286:30 amTYS - ERI
1 stop4h 16mAmerican Airlines
Deal found 11/17$488
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amERI - TYS
1 stop6h 59mAmerican Airlines
Sat 11/296:30 amTYS - ERI
1 stop4h 16mAmerican Airlines
Deal found 11/17$493
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:11 pmERI - TYS
1 stop4h 44mAmerican Airlines
Tue 12/235:00 amTYS - ERI
1 stop5h 47mAmerican Airlines
Deal found 11/18$507
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amERI - TYS
1 stop6h 59mAmerican Airlines
Fri 11/286:30 amTYS - ERI
1 stop4h 16mAmerican Airlines
Deal found 11/17$508
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amERI - TYS
1 stop7h 09mAmerican Airlines
Fri 12/126:05 amTYS - ERI
1 stop6h 14mAmerican Airlines
Deal found 11/18$794

Cheap flight deals from Erie to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Erie (ERI) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$507
(American Airlines)

One-way from

$397
(American Airlines)
Provider with most accurate pricing for Erie-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Erie-Knoxville McGhee Tyson flights.
Search Deals
From Erie to Knoxville McGhee Tyson
Search Deals
One-way flight from Erie to Knoxville McGhee Tyson
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Erie to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Erie to Knoxville that are best for you.

Fly from

Erie

Fly to

Knoxville

Route

Depart

Return

Price

ErieKnoxville

ERI - TYS

ERITYS

Erie

Tue 12/16

6:11 pm-10:55 pm

1 stop4h 44m

Knoxville McGhee Tyson

Tue 12/23

5:00 am-10:47 am

1 stop5h 47m

$507

ErieKnoxville

ERI - TYS

ERITYS

Erie

Sat 3/28

12:00 pm-3:46 pm

1 stop3h 46m

Knoxville McGhee Tyson

Wed 4/1

12:40 pm-4:13 pm

1 stop3h 33m

$548

ErieKnoxville

ERI - TYS

ERITYS

Erie

Thu 5/7

6:21 am-7:00 pm

2 stops12h 39m

Knoxville McGhee Tyson

Tue 5/19

12:50 pm-4:31 pm

1 stop3h 41m

$699

ErieKnoxville

ERI - TYS

ERITYS

Erie

Thu 12/11

6:00 am-1:09 pm

1 stop7h 09m

Knoxville McGhee Tyson

Fri 12/12

6:05 am-12:19 pm

1 stop6h 14m

$794

ErieKnoxville

ERI - TYS

ERITYS

Erie

Sun 11/23

11:16 am-4:38 pm

1 stop5h 22m

$397

ErieKnoxville

ERI - TYS

ERITYS

Erie

Thu 2/12

11:35 am-5:12 pm

1 stop5h 37m

$397

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Compare providers for flights from Erie to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Erie to Knoxville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Erie-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Erie-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Erie-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Erie-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Erie-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Erie to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Erie with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Erie to Knoxville

What is the cheapest month to book a flight from Erie to Knoxville?

Currently, December is the cheapest month in which you can book a flight from Erie to Knoxville (average of $163). Flying from Erie to Knoxville in November is currently the most expensive (average of $254). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 18, 2025.
Read through reviews of airlines operating flights from Erie to Knoxville, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,045 reviews

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Crew

8.0

Food

6.4

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,045 reviews
American Airlines
7.2
Good
11,045 reviews

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Crew

8.0

Food

6.4

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Erie to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Erie to Knoxville?

    Airlines like American Airlines fly from Erie to Knoxville in about 4h 44m. The time it takes to get you to your destination can typically vary by up to . Erie and Knoxville are separated by a distance of 479 mi.

  • Can I find deals for flights from Erie to Knoxville that include hotel bookings?

    Yes. In addition to deals on Erie to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Erie to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Erie to Knoxville.

  • Can I find deals for business class flights from Erie to Knoxville?

    Yes. Cheapflights offers flight deals from Erie to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Erie to Knoxville?

    Currently, December is the cheapest month in which you can book a flight from Erie to Knoxville (average of $163). Flying from Erie to Knoxville in November is currently the most expensive (average of $254). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Erie to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Nashville flights
John F Kennedy Intl to Nashville flights
LaGuardia to Nashville flights
Reagan-National to Nashville flights
Dulles Intl to Nashville flights
Philadelphia to Nashville flights
John F Kennedy Intl to Memphis flights
LaGuardia to Memphis flights
John F Kennedy Intl to Knoxville flights
LaGuardia to Knoxville flights
Newark to Memphis flights
Dulles Intl to Memphis flights
Reagan-National to Memphis flights
Newark to Knoxville flights
Pittsburgh to Nashville flights
Dulles Intl to Knoxville flights
Reagan-National to Knoxville flights
Philadelphia to Knoxville flights
Philadelphia to Memphis flights
Allentown to Nashville flights
Dulles Intl to Chattanooga flights
LaGuardia to Chattanooga flights
Newark to Chattanooga flights
Pittsburgh to Memphis flights
Harrisburg to Nashville flights
Reagan-National to Chattanooga flights
John F Kennedy Intl to Chattanooga flights
Philadelphia to Chattanooga flights
John F Kennedy Intl to Blountville flights
LaGuardia to Blountville flights
Newark to Blountville flights
Pittsburgh to Knoxville flights
Scranton to Nashville flights
Pittsburgh to Blountville flights
Dulles Intl to Blountville flights
Pittsburgh to Chattanooga flights
Harrisburg to Knoxville flights
State College to Nashville flights
Allentown to Knoxville flights
Harrisburg to Chattanooga flights
Harrisburg to Memphis flights
Allentown to Blountville flights
Reagan-National to Blountville flights
Allentown to Memphis flights
Scranton to Knoxville flights
State College to Knoxville flights
Allentown to Chattanooga flights
Erie to Nashville flights
Elmira to Nashville flights
Scranton to Memphis flights

Top airline flying from Erie to Knoxville

Discover the top airline that operate flights from Erie to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$373Average$562FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.