Knoxville

$222+ Cheap flights from Ecuador to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — TYS
May 30 — Jun 61
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Ecuador to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Ecuador to Knoxville

Cheapest flights from Ecuador to Knoxville
Explore the most affordable flight options available from Ecuador to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:59 pm
GYE
-
TYS
1 stop11h 26m
Multiple Airlines
Thu 6/47:15 am
TYS
-
GYE
1 stop16h 49m
Multiple Airlines
Deal found 4/25$419
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:50 pm
GYE
-
TYS
2 stops26h 43m
Multiple Airlines
Thu 6/47:15 am
TYS
-
GYE
1 stop16h 49m
Multiple Airlines
Deal found 4/25$482
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:30 am
GYE
-
TYS
2 stops17h 18m
Multiple Airlines
Thu 6/47:15 am
TYS
-
GYE
1 stop16h 49m
Multiple Airlines
Deal found 4/25$485
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:30 am
GYE
-
TYS
2 stops17h 18m
Multiple Airlines
Thu 6/47:15 am
TYS
-
GYE
1 stop16h 49m
Multiple Airlines
Deal found 4/25$489
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:50 pm
GYE
-
TYS
2 stops19h 51m
Multiple Airlines
Thu 6/47:15 am
TYS
-
GYE
1 stop16h 49m
Multiple Airlines
Deal found 4/25$513
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:30 am
GYE
-
TYS
2 stops30h 06m
Multiple Airlines
Thu 6/47:15 am
TYS
-
GYE
1 stop16h 49m
Multiple Airlines
Deal found 4/25$521
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:59 pm
GYE
-
TYS
1 stop11h 26m
Multiple Airlines
Thu 6/47:15 am
TYS
-
GYE
1 stop16h 49m
Multiple Airlines
Deal found 4/25$532
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
UIO
-
TYS
1 stop16h 59m
American Airlines
Sat 9/56:13 am
TYS
-
UIO
2 stops15h 47m
American Airlines
Deal found 4/28$815
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:35 am
UIO
-
TYS
2 stops43h 10m
United Airlines
Sat 8/155:57 pm
TYS
-
UIO
2 stops30h 28m
United Airlines
Deal found 4/30$882
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:05 am
UIO
-
TYS
1 stop15h 54m
American Airlines
Sat 8/156:00 am
TYS
-
UIO
1 stop18h 59m
American Airlines
Deal found 4/30$913
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:25 am
UIO
-
TYS
2 stops36h 31m
United Airlines
Sun 9/135:45 am
TYS
-
UIO
2 stops24h 15m
United Airlines
Deal found 4/29$940
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1311:59 pm
UIO
-
TYS
1 stop23h 00m
American Airlines
Sun 9/138:39 pm
TYS
-
UIO
2 stops23h 06m
American Airlines
Deal found 4/29$958

Find flight deals from Ecuador to Knoxville

Keep the following information in mind while searching for Ecuador to Knoxville flight deals. Data was last updated April 30, 2026.

Round-trip from

$419
(Kiwi.com)

One-way from

$222
(Kiwi.com)
From Ecuador to Knoxville McGhee Tyson
One-way flight from Ecuador to Knoxville McGhee Tyson

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ecuador to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Ecuador to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Sun 5/10

11:59 pm-12:25 pm

1 stop11h 26m

Knoxville McGhee Tyson

Thu 6/4

7:15 am-11:04 pm

1 stop16h 49m

$419

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Fri 10/23

8:25 am-8:22 am

2 stops22h 57m

Knoxville McGhee Tyson

Fri 10/30

8:37 pm-1:33 pm

2 stops17h 56m

$767

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Wed 5/27

6:00 am-11:59 pm

1 stop16h 59m

Knoxville McGhee Tyson

Wed 7/8

6:00 am-10:37 pm

1 stop17h 37m

$790

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Wed 5/13

12:35 am-4:54 pm

2 stops39h 19m

Knoxville McGhee Tyson

Sat 8/15

7:15 am-11:25 pm

1 stop17h 10m

$882

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 6/13

7:25 am-10:42 am

2 stops26h 17m

Knoxville McGhee Tyson

Sun 9/13

5:45 am-5:00 am

2 stops24h 15m

$940
Quickest round-trip

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 5/16

11:40 pm-5:07 pm

2 stops16h 27m

Knoxville McGhee Tyson

Fri 8/14

1:46 pm-11:59 pm

2 stops11h 13m

$971

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 5/10

7:25 am-6:11 pm

1 stop9h 46m

Knoxville McGhee Tyson

Thu 5/14

6:01 pm-11:25 pm

2 stops30h 24m

$1,143
Cheapest one-way

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Thu 5/7

6:50 pm-11:06 am

2 stops39h 16m

$324

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 6/13

5:20 pm-10:47 pm

2 stops28h 27m

$339

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Fri 5/8

3:30 am-12:24 pm

3 stops31h 54m

$408

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Best time to book a flight from Ecuador to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ecuador with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ecuador to Knoxville
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 30, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Ecuador to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Ecuador to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Knoxville from Ecuador?

    If you book a flight to Knoxville from Ecuador, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Ecuador to Knoxville?

    There are many flights that can get you from Ecuador to Knoxville in 43h 10m. Fly via United Airlines to get the fastest option. The distance between Ecuador and Knoxville is about 2507 mi.

  • Can I find deals for flights from Ecuador to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ecuador to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ecuador to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ecuador to Knoxville.

  • Can I find deals for business class flights from Ecuador to Knoxville?

    Yes. Cheapflights offers flight deals from Ecuador to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Ecuador to Knoxville

Discover the top 2 airlines that operate flights from Ecuador to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$743Average$793FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$799Average$835FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.