$76+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Apr 26 — May 31
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Detroit to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in April or March, booked 58 days in advance, depart on a Tuesday or Saturday and return on a Thursday
Cheap flight deals from Detroit to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to KnoxvilleExplore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:05 am
DTW
- TYS
1 stop10h 59m
Multiple Airlines
Wed 4/84:25 pm
TYS
- DTW
1 stop28h 53m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
DTW
- TYS
1 stop19h 16m
Multiple Airlines
Thu 4/95:10 pm
TYS
- DTW
1 stop7h 29m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:05 am
DTW
- TYS
1 stop10h 59m
Multiple Airlines
Thu 4/95:10 pm
TYS
- DTW
1 stop7h 29m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$227
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:20 pm
DTW
- TYS
1 stop7h 30m
Southwest
Wed 6/35:50 pm
TYS
- DTW
1 stop3h 45m
Southwest
Deal found 3/25![Southwest logo]()
$228
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:10 pm
DTW
- TYS
1 stop3h 30m
Southwest
Tue 4/285:50 pm
TYS
- DTW
1 stop3h 45m
Southwest
Deal found 3/26![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:45 am
DTW
- TYS
1 stop16h 20m
Multiple Airlines
Mon 4/136:20 pm
TYS
- DTW
2 stops23h 47m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:40 pm
DTW
- TYS
2 stops8h 10m
Southwest
Sat 5/25:40 pm
TYS
- DTW
1 stop3h 45m
Southwest
Deal found 3/26![Southwest logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
DTW
- TYS
1 stop19h 16m
Multiple Airlines
Wed 4/84:25 pm
TYS
- DTW
1 stop8h 14m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$243
Best flights from Detroit to KnoxvilleDiscover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 27, 2026.
Discover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 27, 2026.
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:15 am
DTW
- TYS
1 stop5h 25m
Southwest
Tue 5/127:05 am
TYS
- DTW
1 stop5h 35m
Southwest
Deal found 3/25![Southwest logo]()
$244
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:45 pm
DTW
- TYS
Nonstop1h 35m
Delta
Fri 4/247:50 am
TYS
- DTW
Nonstop1h 40m
Delta
Deal found 3/26![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:10 am
DTW
- TYS
2 stops11h 00m
Southwest
Sat 5/96:40 am
TYS
- DTW
2 stops9h 30m
Southwest
Deal found 3/25![Southwest logo]()
$272
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:00 pm
DTW
- TYS
1 stop4h 20m
Southwest
Tue 4/145:50 pm
TYS
- DTW
1 stop3h 45m
Southwest
Deal found 3/23![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
DTW
- TYS
1 stop4h 02m
Delta
Thu 4/237:50 am
TYS
- DTW
Nonstop1h 40m
Delta
Deal found 3/26![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/103:00 pm
DTW
- TYS
1 stop6h 05m
Southwest
Sat 5/166:40 am
TYS
- DTW
1 stop8h 20m
Southwest
Deal found 3/25![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:15 pm
DTW
- TYS
1 stop4h 53m
Delta
Sun 5/107:51 am
TYS
- DTW
Nonstop1h 39m
Delta
Deal found 3/25![Delta logo]()
$409
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:35 pm
DTW
- TYS
1 stop5h 40m
Southwest
Sun 5/107:35 pm
TYS
- DTW
1 stop3h 30m
Southwest
Deal found 3/23![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:10 pm
DTW
- TYS
Nonstop1h 33m
Delta
Tue 4/145:54 pm
TYS
- DTW
1 stop6h 50m
Delta
Deal found 3/22![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:00 pm
DTW
- TYS
2 stops7h 20m
Southwest
Thu 4/238:05 am
TYS
- DTW
2 stops13h 05m
Southwest
Deal found 3/26![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:25 am
DTW
- TYS
1 stop4h 24m
Delta
Sat 6/137:11 am
TYS
- DTW
Nonstop1h 49m
Delta
Deal found 3/26![Delta logo]()
$458
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/102:03 pm
DTW
- TYS
1 stop6h 32m
Delta
Sun 4/127:40 am
TYS
- DTW
Nonstop1h 40m
Delta
Deal found 3/22![Delta logo]()
$459
Last-minute flights from Detroit to KnoxvilleDiscover last-minute flight deals from Detroit to Knoxville. Data last updated March 27, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Knoxville. Data last updated March 27, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
DTW
- TYS
1 stop19h 16m
Multiple Airlines
Thu 4/95:10 pm
TYS
- DTW
1 stop7h 29m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
DTW
- TYS
1 stop19h 16m
Multiple Airlines
Wed 4/84:25 pm
TYS
- DTW
1 stop8h 14m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:05 am
DTW
- TYS
1 stop10h 59m
Multiple Airlines
Wed 4/84:25 pm
TYS
- DTW
1 stop28h 53m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:05 am
DTW
- TYS
1 stop10h 59m
Multiple Airlines
Thu 4/95:10 pm
TYS
- DTW
1 stop7h 29m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:45 am
DTW
- TYS
1 stop16h 20m
Multiple Airlines
Mon 4/136:20 pm
TYS
- DTW
2 stops23h 47m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:10 am
DTW
- TYS
1 stop5h 50m
Southwest
Tue 4/215:50 pm
TYS
- DTW
1 stop3h 45m
Southwest
Deal found 3/23![Southwest logo]()
$246
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:10 pm
DTW
- TYS
1 stop3h 30m
Southwest
Tue 4/285:50 pm
TYS
- DTW
1 stop3h 45m
Southwest
Deal found 3/26![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:35 pm
DTW
- TYS
1 stop5h 40m
Southwest
Sat 5/25:40 pm
TYS
- DTW
1 stop3h 45m
Southwest
Deal found 3/26![Southwest logo]()
$245
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:40 pm
DTW
- TYS
2 stops8h 10m
Southwest
Sat 5/25:40 pm
TYS
- DTW
1 stop3h 45m
Southwest
Deal found 3/26![Southwest logo]()
$239
One-way flights from Detroit to KnoxvilleSearch for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 27, 2026.
Search for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 27, 2026.
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Deal found 3/25![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:28 pm
DTW
- TYS
1 stop24h 20m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:04 pm
DTW
- TYS
2 stops20h 37m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:17 pm
DTW
- TYS
1 stop21h 49m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:09 pm
DTW
- TYS
2 stops22h 32m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:05 pm
DTW
- TYS
2 stops20h 36m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:43 pm
DTW
- TYS
2 stops37h 53m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$118
Find flight deals from Detroit to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $224 (Kiwi.com) |
One-way from | $76 (Expedia) |
Popular in | January |
Cheapest in | April |
Average price | $379 |
Good round-trip deal | $299 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Sat 5/9
6:15 am-11:40 am
1 stop5h 25m
Knoxville McGhee Tyson
Tue 5/12
7:05 am-12:40 pm
1 stop5h 35m
$244
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Wed 5/6
6:10 am-5:10 pm
2 stops11h 00m
Knoxville McGhee Tyson
Sat 5/9
6:40 am-4:10 pm
2 stops9h 30m
$272
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Fri 4/10
4:00 pm-8:20 pm
1 stop4h 20m
Knoxville McGhee Tyson
Tue 4/14
5:50 pm-9:35 pm
1 stop3h 45m
$342
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Sun 5/10
3:00 pm-9:05 pm
1 stop6h 05m
Knoxville McGhee Tyson
Sat 5/16
6:40 am-3:00 pm
1 stop8h 20m
$349
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Fri 5/8
3:35 pm-9:15 pm
1 stop5h 40m
Knoxville McGhee Tyson
Sun 5/10
7:35 pm-11:05 pm
1 stop3h 30m
$373
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Thu 4/16
1:00 pm-8:20 pm
2 stops7h 20m
Knoxville McGhee Tyson
Thu 4/23
8:05 am-9:10 pm
2 stops13h 05m
$373
Quickest round-trip
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Fri 4/17
7:45 pm-9:20 pm
Nonstop1h 35m
Knoxville McGhee Tyson
Fri 4/24
7:50 am-9:30 am
Nonstop1h 40m
$379
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Thu 4/16
5:20 am-9:22 am
1 stop4h 02m
Knoxville McGhee Tyson
Thu 4/23
7:50 am-9:30 am
Nonstop1h 40m
$389
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Wed 5/6
12:15 pm-5:08 pm
1 stop4h 53m
Knoxville McGhee Tyson
Sun 5/10
7:51 am-9:30 am
Nonstop1h 39m
$409
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Mon 4/6
3:10 pm-4:43 pm
Nonstop1h 33m
Knoxville McGhee Tyson
Tue 4/14
5:54 pm-12:44 am
1 stop6h 50m
$419
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Detroit to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
DTW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville
Prices
Airlines
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from Detroit to Knoxville. Price data was last updated on March 13, 2026.
The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 56 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $212). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in December is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to TYS?
Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 27, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit Metropolitan Wayne County Airport to Knoxville as you normally would.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 27, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from Detroit
Popular flights
Alternative routes for Detroit to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to Knoxville by cabin class
Find flights from Detroit to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 27, 2026.
Detroit and Knoxville flights
Browse other Detroit and Knoxville flight options. Last updated on March 27, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on March 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Detroit to Knoxville
Discover the top 2 airlines that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$418 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$417 | FlexibilityNo cancel fee | On-timeN/A |