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Knoxville

$87+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Find cheap flights from Detroit to Knoxville with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in October or July, booked 71 days in advance, depart on a Saturday or Tuesday and return on a Thursday

Cheap flight deals from Detroit to Knoxville

Cheapest flights from Detroit to Knoxville
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:40 pmDTW - TYS
1 stop24h 19mMultiple Airlines
Fri 1/98:30 amTYS - DTW
2 stops13h 38mMultiple Airlines
Deal found 12/26$370
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:52 pmDTW - TYS
Nonstop1h 40mDelta
Fri 1/97:30 amTYS - DTW
Nonstop1h 54mDelta
Deal found 12/26$469
This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:27 pmDTW - TYS
1 stop14h 31mMultiple Airlines
Mon 1/57:15 amTYS - DTW
1 stop25h 28mMultiple Airlines
Deal found 12/27$483
This Kiwi.com deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:28 pmDTW - TYS
1 stop14h 32mMultiple Airlines
Sun 1/47:15 amTYS - DTW
1 stop24h 14mMultiple Airlines
Deal found 12/27$494
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:52 pmDTW - TYS
Nonstop1h 40mDelta
Sun 1/47:39 amTYS - DTW
Nonstop1h 50mDelta
Deal found 12/27$499
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:56 pmDTW - TYS
1 stop4h 19mDelta
Sat 1/37:30 amTYS - DTW
Nonstop1h 50mDelta
Deal found 12/27$509
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:07 amDTW - TYS
1 stop6h 21mAmerican Airlines
Sat 1/35:08 pmTYS - DTW
1 stop6h 47mAmerican Airlines
Deal found 12/27$519
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:52 pmDTW - TYS
Nonstop1h 40mDelta
Tue 12/307:39 amTYS - DTW
Nonstop1h 50mDelta
Deal found 12/26$539

Find flight deals from Detroit to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$199
(Kiwi.com)

One-way from

$87
(Frontier)

Popular in

May

Cheapest in

October

Average price

$439

Good round-trip deal

$339 or less

Good one-way deal

$448 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Knoxville McGhee Tyson flights.
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From Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
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One-way flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 0% potential increase in price ($4 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.

Fly from

Detroit

Fly to

Knoxville

Route

Depart

Return

Price

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 1/26

5:00 am-12:05 pm

1 stop7h 05m

Knoxville McGhee Tyson

Mon 2/2

7:15 am-12:19 am

1 stop17h 04m

$199

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 1/12

5:00 am-12:05 pm

1 stop7h 05m

Knoxville McGhee Tyson

Fri 1/16

7:15 am-7:56 am

1 stop24h 41m

$270

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 1/7

5:58 pm-12:49 pm

1 stop18h 51m

Knoxville McGhee Tyson

Sat 1/10

8:30 am-9:46 am

1 stop25h 16m

$284

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Fri 2/6

7:00 pm-8:47 pm

Nonstop1h 47m

Knoxville McGhee Tyson

Sun 2/8

7:30 am-9:24 am

Nonstop1h 54m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 1/26

10:20 am-12:13 pm

Nonstop1h 53m

Knoxville McGhee Tyson

Mon 2/2

7:30 am-9:24 am

Nonstop1h 54m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Fri 2/6

7:00 pm-8:47 pm

Nonstop1h 47m

Knoxville McGhee Tyson

Mon 2/9

2:37 pm-6:55 pm

1 stop4h 18m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 3/19

3:10 pm-4:43 pm

Nonstop1h 33m

Knoxville McGhee Tyson

Mon 3/23

5:01 pm-10:17 pm

1 stop5h 16m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 3/17

6:00 am-11:50 am

1 stop5h 50m

Knoxville McGhee Tyson

Mon 3/23

7:25 pm-11:05 pm

1 stop3h 40m

$317

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 3/19

4:09 pm-8:08 am

1 stop15h 59m

Knoxville McGhee Tyson

Mon 3/23

8:58 am-12:39 am

1 stop15h 41m

$317

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 1/22

10:20 am-12:13 pm

Nonstop1h 53m

Knoxville McGhee Tyson

Thu 1/29

7:30 am-9:24 am

Nonstop1h 54m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 21 results
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Compare providers for flights from Detroit to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Knoxville. Price data was last updated on December 19, 2025.

The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 71 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $212). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in June is currently the most expensive (average of $283). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to TYS?

Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to Knoxville in the morning. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Knoxville. Price data was last updated on December 20, 2025.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Knoxville flight should consider departing on Saturday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated December 28, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,019 reviews
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,072 reviews
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Knoxville?

    To fly from Detroit to Knoxville, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to McGhee Tyson (TYS). Nonstop flights to Knoxville McGhee Tyson from Detroit Metropolitan Wayne County take 1h 33m on average. When it comes time to book airfare, you have a few options: there are 3 outbound flights from Detroit Metropolitan Wayne County to McGhee Tyson offered by 2 different airlines.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    There are many flights that can get you from Detroit Metropolitan Wayne County Airport to Knoxville in 1h 47m. Fly via Delta to get the fastest option. There are 444 mi between Detroit Metropolitan Wayne County Airport and Knoxville. Most flights are nonstop.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Knoxville round-trip?

    American Airlines, at $216, was found to be the cheapest airline from Detroit Metropolitan Wayne County Airport to Knoxville. An alternate airline flying to your destination would be Delta. You may be able to fly from Detroit Metropolitan Wayne County Airport to Knoxville for 50% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Knoxville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Knoxville on time: Aeromexico (100%), Air France (96%), KLM (78%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Knoxville?

    The cheapest flight price from Detroit Metropolitan Wayne County Airport to Knoxville is $299. On average you can expect to pay $713. The most popular route, (Detroit Metropolitan Wayne County - Knoxville McGhee Tyson), can usually be booked for $231.

  • Can I find deals for flights from Detroit to Knoxville that include hotel bookings?

    Yes. In addition to deals on Detroit to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Knoxville.

  • Can I find deals for business class flights from Detroit to Knoxville?

    Yes. Cheapflights offers flight deals from Detroit to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $212). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in June is currently the most expensive (average of $283). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Detroit to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Detroit to Knoxville

Discover the top 2 airlines that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$418FlexibilityNo cancel feeOn-time71%
DeltaCheapest$299Average$453FlexibilityNo cancel feeOn-timeN/A

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