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$117+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Oct 29 — Nov 51
Wed 10/29
Wed 11/5
1 adult, Economy
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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in January or December, booked 71 days in advance, depart on a Saturday or Wednesday and return on a Thursday

Cheap flight deals from Detroit to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$211
(Kiwi.com)

One-way from

$117
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$419

Good round-trip deal

$359 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Knoxville McGhee Tyson flights.
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From Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
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One-way flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson.
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Find flight deals from Detroit to Knoxville

Cheapest flights from Detroit to Knoxville
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2310:25 pmDTW - TYS
1 stop23h 48mMultiple Airlines
Sat 11/15:06 pmTYS - DTW
1 stop17h 52mMultiple Airlines
Deal found 9/27$211
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:05 amDTW - TYS
1 stop29h 33mMultiple Airlines
Sat 11/110:17 amTYS - DTW
1 stop11h 55mMultiple Airlines
Deal found 9/28$215
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:15 pmDTW - TYS
1 stop20h 18mMultiple Airlines
Sat 11/110:17 amTYS - DTW
1 stop11h 55mMultiple Airlines
Deal found 9/27$222
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/511:26 amDTW - TYS
1 stop9h 38mMultiple Airlines
Sat 11/87:30 amTYS - DTW
1 stop10h 30mMultiple Airlines
Deal found 9/27$225
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:29 pmDTW - TYS
1 stop15h 34mMultiple Airlines
Tue 11/47:30 amTYS - DTW
1 stop6h 33mMultiple Airlines
Deal found 9/27$235
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:52 amDTW - TYS
1 stop6h 11mMultiple Airlines
Tue 10/218:00 amTYS - DTW
1 stop24h 20mMultiple Airlines
Deal found 9/28$239
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:00 amDTW - TYS
1 stop13h 32mMultiple Airlines
Mon 11/38:30 amTYS - DTW
1 stop14h 59mMultiple Airlines
Deal found 9/27$254

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 29, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.

Fly from

Detroit

Fly to

Knoxville

Route

Depart

Return

Price

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 12/13

6:20 pm-8:00 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Tue 12/16

7:39 am-9:29 am

Nonstop1h 50m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 11/5

9:30 am-11:04 am

Nonstop1h 34m

Knoxville McGhee Tyson

Sat 11/8

7:45 am-9:30 am

Nonstop1h 45m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 11/20

6:20 pm-8:00 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Mon 11/24

12:49 pm-2:36 pm

Nonstop1h 47m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 11/19

6:20 pm-8:00 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Sun 11/23

7:39 am-9:30 am

Nonstop1h 51m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 10/27

8:30 am-2:43 pm

1 stop6h 13m

Knoxville McGhee Tyson

Mon 11/3

7:45 am-9:30 am

Nonstop1h 45m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 10/29

7:35 pm-9:13 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Wed 11/5

5:44 am-11:10 am

1 stop5h 26m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 10/25

7:35 pm-9:13 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Sat 11/1

12:47 pm-2:30 pm

Nonstop1h 43m

$319

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Fri 11/7

12:58 pm-1:01 pm

1 stop24h 03m

Knoxville McGhee Tyson

Mon 11/10

10:15 am-6:12 pm

2 stops7h 57m

$329

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 10/27

6:00 am-7:32 pm

1 stop13h 32m

$117

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 10/30

9:05 pm-10:03 am

2 stops36h 58m

$133

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/27

Showing 1-10 of 15 results
1
2

Compare providers for flights from Detroit to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in September.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Knoxville. Price data was last updated on September 26, 2025.

The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 71 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $294). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to TYS?

Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to Knoxville at noon. If you’re flexible enough to do this you can expect to save up to 8% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Knoxville. Price data was last updated on September 28, 2025.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Knoxville flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 29, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,964 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,964 reviews
Delta
8.0
Very good
7,964 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,964 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Knoxville?

    To fly from Detroit to Knoxville, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to McGhee Tyson (TYS). Nonstop flights to Knoxville McGhee Tyson from Detroit Metropolitan Wayne County take 1h 34m on average. When it comes time to book airfare, you have a few options: there are 8 outbound flights from Detroit Metropolitan Wayne County to McGhee Tyson offered by 2 different airlines.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    There are many flights that can get you from Detroit Metropolitan Wayne County Airport to Knoxville in 1h 40m. Fly via Delta to get the fastest option. There are 444 mi between Detroit Metropolitan Wayne County Airport and Knoxville. Most flights are nonstop.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Knoxville round-trip?

    American Airlines, at $216, was found to be the cheapest airline from Detroit Metropolitan Wayne County Airport to Knoxville. An alternate airline flying to your destination would be Delta. You may be able to fly from Detroit Metropolitan Wayne County Airport to Knoxville for 50% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Knoxville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Knoxville on time: Delta (74%), Endeavor Airlines (74%), WestJet (73%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Knoxville?

    The cheapest flight price from Detroit Metropolitan Wayne County Airport to Knoxville is $218. On average you can expect to pay $344. The most popular route, (Detroit Metropolitan Wayne County - Knoxville McGhee Tyson), can usually be booked for $225.

  • Can I find deals for flights from Detroit to Knoxville that include hotel bookings?

    Yes. In addition to deals on Detroit to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Knoxville.

  • Can I find deals for business class flights from Detroit to Knoxville?

    Yes. Cheapflights offers flight deals from Detroit to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $294). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Detroit to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Detroit to Knoxville

Discover the top 2 airlines that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$418FlexibilityNo cancel feeOn-time71%
DeltaCheapest$309Average$454FlexibilityNo cancel feeOn-timeN/A

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