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$89+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in December or January, booked 71 days in advance, depart on a Saturday or Wednesday and return on a Thursday

Cheap flight deals from Detroit to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$211
(Kiwi.com)

One-way from

$89
(Frontier)

Popular in

May

Cheapest in

December

Average price

$491

Good round-trip deal

$359 or less

Good one-way deal

$248 or less
From Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
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One-way flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 2% potential increase in price ($12 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson.
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Find flight deals from Detroit to Knoxville

Cheapest flights from Detroit to Knoxville
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:00 amDTW - TYS
1 stop9h 35mMultiple Airlines
Mon 11/105:22 pmTYS - DTW
1 stop15h 00mMultiple Airlines
Deal found 8/13$199
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:10 amDTW - TYS
1 stop13h 21mMultiple Airlines
Sun 9/284:22 pmTYS - DTW
1 stop15h 53mMultiple Airlines
Deal found 8/12$207
This Mytrip deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/99:19 pmDTW - TYS
2 stops18h 22mMultiple Airlines
Tue 9/167:30 amTYS - DTW
2 stops15h 10mMultiple Airlines
Deal found 8/12$211
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:50 pmDTW - TYS
1 stop22h 20mMultiple Airlines
Sun 9/284:22 pmTYS - DTW
1 stop15h 53mMultiple Airlines
Deal found 8/12$214
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1311:45 amDTW - TYS
1 stop8h 56mMultiple Airlines
Sat 9/209:31 pmTYS - DTW
1 stop11h 13mMultiple Airlines
Deal found 8/14$215
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:41 amDTW - TYS
1 stop9h 00mMultiple Airlines
Wed 9/174:31 pmTYS - DTW
2 stops16h 09mMultiple Airlines
Deal found 8/13$238
This Mytrip deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/32:53 pmDTW - TYS
1 stop8h 43mMultiple Airlines
Sun 10/55:44 pmTYS - DTW
2 stops14h 56mMultiple Airlines
Deal found 8/12$239

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.

Fly from

Detroit

Fly to

Knoxville

Route

Depart

Return

Price

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Fri 11/7

9:00 am-6:35 pm

1 stop9h 35m

Knoxville McGhee Tyson

Mon 11/10

5:22 pm-8:22 am

1 stop15h 00m

$199

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 9/25

7:10 am-8:31 pm

1 stop13h 21m

Knoxville McGhee Tyson

Sun 9/28

4:22 pm-8:15 am

1 stop15h 53m

$207

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 9/13

11:45 am-8:41 pm

1 stop8h 56m

Knoxville McGhee Tyson

Mon 9/15

8:32 pm-8:15 am

1 stop11h 43m

$211

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 9/9

9:19 pm-3:41 pm

2 stops18h 22m

Knoxville McGhee Tyson

Tue 9/16

7:30 am-10:40 pm

2 stops15h 10m

$211

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 9/23

4:50 pm-3:10 pm

1 stop22h 20m

Knoxville McGhee Tyson

Sun 9/28

4:22 pm-8:15 am

1 stop15h 53m

$214

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 9/13

11:45 am-8:41 pm

1 stop8h 56m

Knoxville McGhee Tyson

Sat 9/20

9:31 pm-8:44 am

1 stop11h 13m

$215

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 9/10

7:35 pm-10:19 pm

1 stop26h 44m

Knoxville McGhee Tyson

Wed 9/17

4:00 pm-8:15 am

1 stop16h 15m

$237

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/15

6:10 am-7:45 pm

1 stop13h 35m

$89

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sun 9/14

6:10 am-4:18 pm

1 stop10h 08m

$89

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/15

8:49 pm-12:55 pm

1 stop16h 06m

$104

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 17 results
1
2

Best time to book a flight from Detroit to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Knoxville. Price data was last updated on August 8, 2025.

The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 71 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $294). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to TYS?

Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to Knoxville at noon. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Knoxville. Price data was last updated on August 10, 2025.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Knoxville flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 14, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Knoxville?

    To fly from Detroit to Knoxville, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to McGhee Tyson (TYS). Nonstop flights to Knoxville McGhee Tyson from Detroit Metropolitan Wayne County take 1h 32m on average. When it comes time to book airfare, you have a few options: there are 8 outbound flights from Detroit Metropolitan Wayne County to McGhee Tyson offered by 2 different airlines.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Knoxville round-trip?

    American Airlines, at $259, was found to be the cheapest airline from Detroit Metropolitan Wayne County Airport to Knoxville. An alternate airline flying to your destination would be Delta. You may be able to fly from Detroit Metropolitan Wayne County Airport to Knoxville for 40% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Knoxville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Knoxville on time: WestJet (76%), Delta (65%), Endeavor Airlines (65%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Knoxville?

    The cheapest flight price from Detroit Metropolitan Wayne County Airport to Knoxville is $248. On average you can expect to pay $409. The most popular route, (Detroit Metropolitan Wayne County - Knoxville McGhee Tyson), can usually be booked for $275.

  • Can I find deals for flights from Detroit to Knoxville that include hotel bookings?

    Yes. In addition to deals on Detroit to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Knoxville.

  • Can I find deals for business class flights from Detroit to Knoxville?

    Yes. Cheapflights offers flight deals from Detroit to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $294). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Detroit to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Detroit to Knoxville

Discover the top 2 airlines that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$259Average$379FlexibilityNo cancel feeOn-time71%
DeltaCheapest$309Average$455FlexibilityNo cancel feeOn-timeN/A

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