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Knoxville

$108+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in October or April, booked 71 days in advance, depart on a Saturday or Wednesday and return on a Thursday

Cheap flight deals from Detroit to Knoxville

Cheapest flights from Detroit to Knoxville
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:05 am
DTW
-
TYS
1 stop14h 55m
Multiple Airlines
Mon 3/169:54 pm
TYS
-
DTW
1 stop11h 16m
Multiple Airlines
Deal found 2/9$176
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:05 am
DTW
-
TYS
1 stop9h 10m
Multiple Airlines
Tue 3/174:56 pm
TYS
-
DTW
1 stop16h 14m
Multiple Airlines
Deal found 2/10$177
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:07 pm
DTW
-
TYS
2 stops17h 37m
Multiple Airlines
Wed 3/188:30 am
TYS
-
DTW
1 stop11h 49m
Multiple Airlines
Deal found 2/11$237
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:09 am
DTW
-
TYS
1 stop6h 51m
Multiple Airlines
Mon 3/98:54 pm
TYS
-
DTW
2 stops36h 21m
Multiple Airlines
Deal found 2/10$247
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:07 pm
DTW
-
TYS
2 stops24h 15m
Multiple Airlines
Wed 3/258:30 am
TYS
-
DTW
1 stop7h 54m
Multiple Airlines
Deal found 2/11$256
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/114:15 pm
DTW
-
TYS
1 stop3h 50m
Southwest
Wed 3/186:35 am
TYS
-
DTW
1 stop5h 40m
Southwest
Deal found 2/11$257
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:15 am
DTW
-
TYS
1 stop5h 25m
Southwest
Wed 4/2212:50 pm
TYS
-
DTW
2 stops9h 40m
Southwest
Deal found 2/11$262
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:15 pm
DTW
-
TYS
1 stop3h 50m
Southwest
Tue 3/176:20 pm
TYS
-
DTW
1 stop4h 00m
Southwest
Deal found 2/10$263

Find flight deals from Detroit to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$176
(Kiwi.com)

One-way from

$108
(Kiwi.com)

Popular in

January

Cheapest in

October

Average price

$499

Good round-trip deal

$379 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Knoxville McGhee Tyson flights.
Search Deals
From Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($91 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.

Fly from

Detroit

Fly to

Knoxville

Route

Depart

Return

Price

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 4/18

6:15 am-11:40 am

1 stop5h 25m

Knoxville McGhee Tyson

Wed 4/22

5:50 pm-9:35 pm

1 stop3h 45m

$257

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 3/18

4:15 pm-8:05 pm

1 stop3h 50m

Knoxville McGhee Tyson

Wed 3/25

6:20 pm-10:20 pm

1 stop4h 00m

$263

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 4/7

6:10 am-12:00 pm

1 stop5h 50m

Knoxville McGhee Tyson

Tue 5/5

5:50 pm-9:35 pm

1 stop3h 45m

$263

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 3/17

4:15 pm-8:05 pm

1 stop3h 50m

Knoxville McGhee Tyson

Tue 3/24

6:20 pm-10:20 pm

1 stop4h 00m

$263

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 5/6

3:03 pm-4:42 pm

Nonstop1h 39m

Knoxville McGhee Tyson

Sun 5/10

3:00 pm-4:40 pm

Nonstop1h 40m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 4/2

8:50 am-10:31 am

Nonstop1h 41m

Knoxville McGhee Tyson

Sat 4/11

7:40 am-9:20 am

Nonstop1h 40m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 4/18

8:40 am-10:21 am

Nonstop1h 41m

Knoxville McGhee Tyson

Wed 4/22

7:50 am-9:30 am

Nonstop1h 40m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 3/18

7:34 pm-9:06 pm

Nonstop1h 32m

Knoxville McGhee Tyson

Wed 3/25

11:18 am-1:01 pm

Nonstop1h 43m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 3/7

4:14 pm-10:26 pm

1 stop30h 12m

$108

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 3/9

5:09 am-12:00 pm

1 stop6h 51m

$109

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/8

Showing 1-10 of 14 results
1
2

Compare providers for flights from Detroit to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Knoxville. Price data was last updated on February 6, 2026.

The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 71 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $212). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in December is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to TYS?

Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 12, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit Metropolitan Wayne County Airport to Knoxville as you normally would.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 12, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,180 reviews

Food

7.2

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,180 reviews
Delta
7.9
Good
8,180 reviews

Food

7.2

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,271 reviews
Delta
7.9
Good
8,180 reviews

Food

7.2

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Knoxville?

    To fly from Detroit to Knoxville, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to McGhee Tyson (TYS). Nonstop flights to Knoxville McGhee Tyson from Detroit Metropolitan Wayne County take 1h 32m on average. When it comes time to book airfare, you have a few options: there are 2 outbound flights from Detroit Metropolitan Wayne County to McGhee Tyson offered by 2 different airlines.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    There are many flights that can get you from Detroit Metropolitan Wayne County Airport to Knoxville in 5h 25m. Fly via Southwest to get the fastest option. There are 444 mi between Detroit Metropolitan Wayne County Airport and Knoxville.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Knoxville round-trip?

    American Airlines, at $216, was found to be the cheapest airline from Detroit Metropolitan Wayne County Airport to Knoxville. An alternate airline flying to your destination would be Delta. You may be able to fly from Detroit Metropolitan Wayne County Airport to Knoxville for 52% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Knoxville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Knoxville on time: Aeromexico (100%), KLM (65%), Korean Air (61%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Knoxville?

    The cheapest flight price from Detroit Metropolitan Wayne County Airport to Knoxville is $299. On average you can expect to pay $698. The most popular route, (Detroit Metropolitan Wayne County - Knoxville McGhee Tyson), can usually be booked for $247.

  • Can I find deals for flights from Detroit to Knoxville that include hotel bookings?

    Yes. In addition to deals on Detroit to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Knoxville.

  • Can I find deals for business class flights from Detroit to Knoxville?

    Yes. Cheapflights offers flight deals from Detroit to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    Currently, November is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $212). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in December is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Detroit to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Detroit to Knoxville

Discover the top 2 airlines that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$418FlexibilityNo cancel feeOn-time71%
DeltaCheapest$299Average$428FlexibilityNo cancel feeOn-timeN/A

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