
Most accurate provider | eDreams 3 stars  | 
|---|---|
Most trusted provider | eDreams 3 stars  | 
Round-trip from | $189 (American Airlines)  | 
One-way from | $102 (Kiwi.com)  | 
Popular in | September | 
Cheapest in | February | 
Average price | $297 | 
Good round-trip deal | $240 or less | 
Good one-way deal | $243 or less | 
Fly from
Fly to
Route
Depart
Return
Price
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Tue 12/2
3:43 pm-12:03 pm
1 stop19h 20m
Knoxville McGhee Tyson
Sun 12/7
5:23 pm-4:54 pm
1 stop24h 31m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Fri 1/9
7:42 am-10:32 am
Nonstop1h 50m
Knoxville McGhee Tyson
Sun 1/11
6:45 am-7:48 am
Nonstop2h 03m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Thu 2/26
7:25 am-10:12 am
Nonstop1h 47m
Knoxville McGhee Tyson
Mon 3/2
6:45 am-7:47 am
Nonstop2h 02m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Fri 2/27
6:28 pm-9:10 pm
Nonstop1h 42m
Knoxville McGhee Tyson
Mon 3/2
6:45 am-7:47 am
Nonstop2h 02m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Tue 3/24
6:13 pm-8:54 pm
Nonstop1h 41m
Knoxville McGhee Tyson
Sat 3/28
7:00 am-8:01 am
Nonstop2h 01m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Mon 12/1
6:45 am-1:34 pm
1 stop5h 49m
Knoxville McGhee Tyson
Mon 12/8
7:59 pm-12:01 am
1 stop5h 02m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Fri 12/5
1:20 pm-6:52 pm
1 stop4h 32m
Knoxville McGhee Tyson
Sun 12/7
7:59 pm-12:01 am
1 stop5h 02m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Mon 2/23
7:10 am-4:19 pm
1 stop8h 09m
Knoxville McGhee Tyson
Sat 2/28
7:30 am-1:21 pm
1 stop6h 51m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Fri 1/9
1:54 pm-8:47 pm
1 stop5h 53m
Knoxville McGhee Tyson
Sun 1/11
7:30 am-1:07 pm
1 stop6h 37m
ChicagoKnoxville
ORD - TYS
ORDTYS
Chicago O'Hare Intl
Thu 12/4
11:44 am-9:37 pm
2 stops8h 53m
| Provider | Price Accuracy | Trust Score* | 
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | 
Booking 44 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago O'Hare Intl Airport to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $174). Flying from Chicago O'Hare Intl Airport to Knoxville in September is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from Chicago O'Hare Intl Airport to Knoxville in the morning. Doing so could potentially save you 5% on the flight price compared to flying in the evening, which is usually more expensive.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Knoxville flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Comfort
Food
Overall
Crew
Entertainment
Boarding
Reviews
Sebrena,Oct 2025
IAH - RSW
Comfort
Food
Overall
Crew
Entertainment
Boarding
Reviews
Sebrena,Oct 2025
IAH - RSW
Comfort
Food
Overall
Crew
Entertainment
Boarding
Reviews
Sebrena,Oct 2025
IAH - RSW
| Airline | Cheapest | Average | Flexibility | On-time | 
|---|---|---|---|---|
| Cheapest$189 | Average$301 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$193 | Average$334 | FlexibilityNo cancel fee | On-time69% |