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$101+ Cheap flights from O'Hare Intl (ORD) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — TYS
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago O'Hare Intl to Knoxville McGhee Tyson are usually found in February or August, booked 50 days in advance, depart on a Wednesday or Tuesday and return on a Thursday

Cheap flight deals from O'Hare Intl to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$189
(American Airlines)

One-way from

$101
(Mytrip)

Popular in

July

Cheapest in

February

Average price

$326

Good round-trip deal

$230 or less

Good one-way deal

$283 or less
From Chicago O'Hare Intl to Knoxville McGhee Tyson
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One-way flight from Chicago O'Hare Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 1% potential increase in price ($3 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Chicago O'Hare Intl to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Chicago O'Hare Intl to Knoxville McGhee Tyson.
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Find flight deals from O'Hare Intl to Knoxville

Cheapest flights from O'Hare Intl to Knoxville
Explore the most affordable flight options available from O'Hare Intl to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/61:37 pmORD - TYS
Nonstop1h 42mAmerican Airlines
Sat 9/137:14 amTYS - ORD
Nonstop2h 04mAmerican Airlines
Deal found 7/26$189
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/128:52 amORD - TYS
1 stop5h 06mUnited Airlines
Sat 8/167:00 amTYS - ORD
Nonstop1h 57mUnited Airlines
Deal found 7/26$204
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:15 amORD - TYS
1 stop3h 19mDelta
Thu 9/115:45 amTYS - ORD
1 stop3h 55mDelta
Deal found 7/28$209
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:56 amORD - TYS
1 stop15h 16mMultiple Airlines
Mon 8/251:22 pmTYS - ORD
1 stop10h 00mMultiple Airlines
Deal found 7/29$215
This Frontier deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:00 amORD - TYS
1 stop12h 50mFrontier
Sun 9/75:08 pmTYS - ORD
1 stop7h 51mFrontier
Deal found 7/27$218

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Knoxville that are best for you.

Fly from

O'Hare Intl

Fly to

Knoxville

Route

Depart

Return

Price

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 9/6

6:14 pm-9:00 pm

Nonstop1h 46m

Knoxville McGhee Tyson

Sat 9/13

3:10 pm-4:10 pm

Nonstop2h 00m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 8/12

8:52 am-2:58 pm

1 stop5h 06m

Knoxville McGhee Tyson

Sat 8/16

7:00 am-7:57 am

Nonstop1h 57m

$204

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 9/4

7:15 am-11:34 am

1 stop3h 19m

Knoxville McGhee Tyson

Thu 9/11

5:45 am-8:40 am

1 stop3h 55m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 8/22

6:56 am-11:12 pm

1 stop15h 16m

Knoxville McGhee Tyson

Mon 8/25

1:22 pm-10:22 pm

1 stop10h 00m

$215

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 9/4

6:00 am-7:50 pm

1 stop12h 50m

Knoxville McGhee Tyson

Sun 9/7

5:08 pm-11:59 pm

1 stop7h 51m

$218

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 9/26

6:30 am-5:34 pm

1 stop10h 04m

$101

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sun 8/24

11:44 am-7:41 pm

1 stop6h 57m

$108

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 8/30

6:58 pm-10:04 am

2 stops14h 06m

$201

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 10/25

6:45 am-1:39 pm

1 stop5h 54m

$224

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 8/26

7:24 am-11:57 pm

2 stops15h 33m

$227

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from O'Hare Intl to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Knoxville

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to Knoxville. Price data was last updated on July 25, 2025.

Booking 50 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago O'Hare Intl Airport to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $295). Flying from Chicago O'Hare Intl Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to TYS?

Find hourly flight availability from O'Hare Intl to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s typically best to fly out from Chicago O'Hare Intl Airport to Knoxville in the afternoon. Doing so could potentially save you 9% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Knoxville. Price data was last updated on July 27, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Knoxville flight should consider departing on Wednesday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago O'Hare Intl Airport to Knoxville

Explore weekly flight availability from O'Hare Intl to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 29, 2025.

The most flights from ORD to TYS are scheduled on a Monday (28 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (22 on average).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Chicago O'Hare Intl Airport to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,238 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chicago O'Hare Intl?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Chicago O'Hare Intl to Knoxville. You should not have trouble finding flights to McGhee Tyson from Chicago O'Hare Intl; the airport handles an average of 25 inbound flights from Chicago O'Hare Intl per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Knoxville airport from Chicago O'Hare Intl. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Knoxville round-trip?

    American Airlines, at $189, was found to be the cheapest airline from Chicago O'Hare Intl Airport to Knoxville.Alternate airlines to your destination round-trip include United Airlines and Delta. You may be able to fly from Chicago O'Hare Intl Airport to Knoxville for 35% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Knoxville one-way?

    One-way options have recently been found by users for as low as $108 on Frontier. Other airlines that offer cheap prices include American Airlines from $201 and Delta from $224 one-way.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Knoxville?

    Consider Republic Airways (94%), SkyWest Airlines (81%) or United Airlines (78%) when booking your flight. These represent the most reliable airlines when flying from Chicago O'Hare Intl Airport to Knoxville.

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Knoxville?

    Looking for the cheapest flight from Chicago O'Hare Intl Airport to Knoxville? While on average our users pay $308, our data indicates the cheapest price to be $189. The most popular route (Chicago O'Hare Intl - Knoxville McGhee Tyson), is priced around $189.

  • Can I find deals for flights from O'Hare Intl to Knoxville that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Knoxville.

  • Can I find deals for business class flights from O'Hare Intl to Knoxville?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $295). Flying from Chicago O'Hare Intl Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from O'Hare Intl to Knoxville

Discover the top 3 airlines that operate flights from O'Hare Intl to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$63Average$137FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$174Average$287FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$186Average$317FlexibilityNo cancel feeOn-time69%

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