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Knoxville

$94+ Cheap flights from O'Hare Intl (ORD) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — TYS
oct. 19 — oct. 261
dom. 10/19
dom. 10/26
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago O'Hare Intl to Knoxville McGhee Tyson are usually found in February or August, booked 89 days in advance, depart on a Wednesday or Saturday and return on a Friday

Cheap flight deals from O'Hare Intl to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 19, 2025.

Round-trip from

$189
(American Airlines)

One-way from

$94
(Kiwi.com)

Popular in

October

Cheapest in

February

Average price

$331

Good round-trip deal

$250 or less

Good one-way deal

$128 or less
From Chicago O'Hare Intl to Knoxville McGhee Tyson
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One-way flight from Chicago O'Hare Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 7% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Chicago O'Hare Intl to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Chicago O'Hare Intl to Knoxville McGhee Tyson.
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Find flight deals from O'Hare Intl to Knoxville

Cheapest flights from O'Hare Intl to Knoxville
Explore the most affordable flight options available from O'Hare Intl to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 19, 2025.

This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/158:00 pmORD - TYS
Nonstop1h 50mUnited Airlines
dom. 10/198:50 amTYS - ORD
Nonstop2h 02mUnited Airlines
Deal found 9/18$189
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/17:15 amORD - TYS
Nonstop1h 55mUnited Airlines
mié. 10/810:51 amTYS - ORD
Nonstop2h 04mUnited Airlines
Deal found 9/17$194
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/38:00 pmORD - TYS
Nonstop1h 50mUnited Airlines
lun. 10/67:00 amTYS - ORD
Nonstop1h 55mUnited Airlines
Deal found 9/17$199
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/266:50 amORD - TYS
1 stop11h 42mFrontier
jue. 10/307:17 pmTYS - ORD
2 stops16h 24mFrontier
Deal found 9/15$201
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/181:25 pmORD - TYS
1 stop6h 48mDelta
mié. 10/226:12 amTYS - ORD
1 stop7h 58mDelta
Deal found 9/18$209
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/77:15 amORD - TYS
Nonstop1h 55mUnited Airlines
vie. 10/177:00 amTYS - ORD
Nonstop1h 55mUnited Airlines
Deal found 9/16$211
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/178:00 pmORD - TYS
Nonstop1h 50mUnited Airlines
mar. 10/217:00 amTYS - ORD
Nonstop1h 55mUnited Airlines
Deal found 9/18$213
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/2111:43 amORD - TYS
Nonstop1h 46mAmerican Airlines
dom. 11/235:52 pmTYS - ORD
Nonstop2h 04mAmerican Airlines
Deal found 9/16$219
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/51:15 pmORD - TYS
1 stop7h 14mAmerican Airlines
sáb. 11/85:35 pmTYS - ORD
Nonstop2h 09mAmerican Airlines
Deal found 9/16$224
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/21:37 pmORD - TYS
Nonstop1h 42mAmerican Airlines
lun. 10/68:37 pmTYS - ORD
1 stop4h 16mAmerican Airlines
Deal found 9/16$234

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 19, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Knoxville that are best for you.

Fly from

O'Hare Intl

Fly to

Knoxville

Route

Depart

Return

Price

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

mié. 11/5

7:20 am-10:05 am

Nonstop1h 45m

Knoxville McGhee Tyson

sáb. 11/8

8:26 am-9:30 am

Nonstop2h 04m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

mié. 10/15

8:00 pm-10:50 pm

Nonstop1h 50m

Knoxville McGhee Tyson

dom. 10/19

8:50 am-9:52 am

Nonstop2h 02m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

mié. 10/1

7:15 am-10:10 am

Nonstop1h 55m

Knoxville McGhee Tyson

mié. 10/8

10:51 am-11:55 am

Nonstop2h 04m

$194

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

mié. 11/5

9:52 am-2:51 pm

1 stop3h 59m

Knoxville McGhee Tyson

sáb. 11/8

2:41 pm-6:49 pm

1 stop5h 08m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

vie. 11/14

6:37 pm-9:24 pm

Nonstop1h 47m

Knoxville McGhee Tyson

lun. 11/17

6:16 pm-7:20 pm

Nonstop2h 04m

$243

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

mié. 10/1

12:55 pm-8:39 pm

1 stop6h 44m

Knoxville McGhee Tyson

mié. 10/8

5:19 pm-10:26 pm

1 stop6h 07m

$248

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

vie. 10/3

12:55 pm-8:39 pm

1 stop6h 44m

Knoxville McGhee Tyson

lun. 10/6

8:10 pm-11:58 pm

1 stop4h 48m

$249

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

mar. 11/11

7:20 am-10:05 am

Nonstop1h 45m

Knoxville McGhee Tyson

jue. 11/13

10:50 am-11:53 am

Nonstop2h 03m

$257

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

dom. 10/26

7:20 am-10:05 am

Nonstop1h 45m

Knoxville McGhee Tyson

jue. 10/30

8:26 am-9:30 am

Nonstop2h 04m

$257

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

mar. 9/23

11:59 am-2:46 pm

Nonstop1h 47m

Knoxville McGhee Tyson

sáb. 9/27

6:25 am-12:02 pm

1 stop6h 37m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/18

Showing 1-10 of 23 results
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Best time to book a flight from O'Hare Intl to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Knoxville

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to Knoxville. Price data was last updated on September 12, 2025.

Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago O'Hare Intl Airport to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $295). Flying from Chicago O'Hare Intl Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to TYS?

Find hourly flight availability from O'Hare Intl to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 19, 2025.

It’s typically best to fly out from Chicago O'Hare Intl Airport to Knoxville in the morning. Doing so could potentially save you 7% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Knoxville. Price data was last updated on September 14, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Knoxville flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated septiembre 19, 2025.
See what other customers who have flown with United Airlines and American Airlines from Chicago O'Hare Intl Airport to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,926 reviews

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chicago O'Hare Intl?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Chicago O'Hare Intl to Knoxville. You should not have trouble finding flights to McGhee Tyson from Chicago O'Hare Intl; the airport handles an average of 23 inbound flights from Chicago O'Hare Intl per day. You should also have plenty of airline options to choose from since 2 airlines have flights to the Knoxville airport from Chicago O'Hare Intl. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Chicago O'Hare Intl Airport to Knoxville?

    There are many flights that can get you from Chicago O'Hare Intl Airport to Knoxville in 1h 45m. Fly via United Airlines or Delta to get the fastest option. Chicago O'Hare Intl Airport and Knoxville are separated by a distance of 475 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Knoxville round-trip?

    American Airlines, at $180, was found to be the cheapest airline from Chicago O'Hare Intl Airport to Knoxville. An alternate airline flying to your destination would be United Airlines. You may be able to fly from Chicago O'Hare Intl Airport to Knoxville for 40% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Knoxville?

    Consider GoJet (90%), Republic Airways (85%) or Envoy Air (82%) when booking your flight. These represent the most reliable airlines when flying from Chicago O'Hare Intl Airport to Knoxville.

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Knoxville?

    Looking for the cheapest flight from Chicago O'Hare Intl Airport to Knoxville? While on average our users pay $301, our data indicates the cheapest price to be $128. The most popular route (Chicago O'Hare Intl - Knoxville McGhee Tyson), is priced around $189.

  • Can I find deals for flights from O'Hare Intl to Knoxville that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Knoxville.

  • Can I find deals for business class flights from O'Hare Intl to Knoxville?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $295). Flying from Chicago O'Hare Intl Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 2 airlines flying from O'Hare Intl to Knoxville

Discover the top 2 airlines that operate flights from O'Hare Intl to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$180Average$300FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$190Average$335FlexibilityNo cancel feeOn-time69%

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