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$95+ Cheap flights from O'Hare Intl (ORD) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — TYS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago O'Hare Intl to Knoxville McGhee Tyson are usually found in August or February, booked 44 days in advance, depart on a Saturday or Wednesday and return on a Friday

Cheap flight deals from O'Hare Intl to Knoxville

Cheapest flights from O'Hare Intl to Knoxville
Explore the most affordable flight options available from O'Hare Intl to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:38 pmORD - TYS
1 stop18h 22mMultiple Airlines
Thu 1/81:39 pmTYS - ORD
1 stop8h 52mMultiple Airlines
Deal found 12/17$229
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:11 pmORD - TYS
Nonstop1h 45mAmerican Airlines
Fri 1/25:42 amTYS - ORD
1 stop5h 21mAmerican Airlines
Deal found 12/16$259
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:07 pmORD - TYS
Nonstop1h 53mUnited Airlines
Thu 1/86:45 amTYS - ORD
Nonstop2h 03mUnited Airlines
Deal found 12/17$264
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:07 amORD - TYS
1 stop6h 00mAmerican Airlines
Mon 12/295:08 pmTYS - ORD
Nonstop2h 12mAmerican Airlines
Deal found 12/15$269
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:54 pmORD - TYS
1 stop7h 04mAmerican Airlines
Wed 12/312:58 pmTYS - ORD
Nonstop2h 10mAmerican Airlines
Deal found 12/16$274
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:38 pmORD - TYS
1 stop18h 22mMultiple Airlines
Wed 1/73:53 pmTYS - ORD
2 stops20h 42mMultiple Airlines
Deal found 12/17$289
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amORD - TYS
1 stop7h 31mFrontier
Tue 12/304:46 pmTYS - ORD
1 stop8h 26mFrontier
Deal found 12/16$293
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:30 amORD - TYS
Nonstop1h 43mUnited Airlines
Tue 12/236:45 amTYS - ORD
Nonstop2h 07mUnited Airlines
Deal found 12/16$294
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:00 amORD - TYS
1 stop5h 32mAmerican Airlines
Tue 12/237:48 amTYS - ORD
Nonstop2h 02mAmerican Airlines
Deal found 12/16$304
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:48 pmORD - TYS
Nonstop1h 51mUnited Airlines
Mon 12/2911:00 amTYS - ORD
Nonstop1h 58mUnited Airlines
Deal found 12/15$305

Find flight deals from O'Hare Intl to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$149
(Kiwi.com)

One-way from

$95
(Mytrip)

Popular in

December

Cheapest in

August

Average price

$366

Good round-trip deal

$279 or less

Good one-way deal

$158 or less
Provider with most accurate pricing for Chicago O'Hare Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Knoxville McGhee Tyson flights.
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From Chicago O'Hare Intl to Knoxville McGhee Tyson
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One-way flight from Chicago O'Hare Intl to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Chicago O'Hare Intl to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Chicago O'Hare Intl to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Knoxville that are best for you.

Fly from

O'Hare Intl

Fly to

Knoxville

Route

Depart

Return

Price

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 2/6

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 2/8

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 1/30

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Mon 2/2

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 1/9

10:35 am-1:24 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Mon 1/12

5:29 pm-6:27 pm

Nonstop1h 58m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 1/30

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 2/1

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 1/9

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 1/11

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 2/20

6:15 pm-8:57 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Mon 2/23

6:45 am-7:47 am

Nonstop2h 02m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 2/5

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sat 2/7

1:59 pm-2:55 pm

Nonstop1h 56m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 1/8

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Tue 1/13

5:29 pm-6:27 pm

Nonstop1h 58m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 1/8

8:43 pm-1:40 pm

1 stop15h 57m

Knoxville McGhee Tyson

Mon 1/12

12:55 pm-1:13 pm

1 stop25h 18m

$205

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 1/8

1:55 pm-8:47 pm

1 stop5h 52m

Knoxville McGhee Tyson

Tue 1/13

5:40 am-10:59 am

1 stop6h 19m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 21 results
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Compare providers for flights from O'Hare Intl to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Knoxville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Chicago O'Hare Intl Airport-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Knoxville

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to Knoxville. Price data was last updated on December 12, 2025.

Booking 44 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago O'Hare Intl Airport to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?

Currently, April is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $179). Flying from Chicago O'Hare Intl Airport to Knoxville in September is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to TYS?

Find hourly flight availability from O'Hare Intl to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s typically best to fly out from Chicago O'Hare Intl Airport to Knoxville in the afternoon. Doing so could potentially save you 7% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Knoxville. Price data was last updated on December 13, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Knoxville flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated December 18, 2025.
See what other customers who have flown with United Airlines and American Airlines from Chicago O'Hare Intl Airport to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,091 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability
United Airlines
7.4
Good
9,091 reviews
United Airlines
7.4
Good
9,091 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability
American Airlines
7.2
Good
11,054 reviews
United Airlines
7.4
Good
9,091 reviews

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chicago O'Hare Intl?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Chicago O'Hare Intl to Knoxville. You should not have trouble finding flights to McGhee Tyson from Chicago O'Hare Intl; the airport handles an average of 10 inbound flights from Chicago O'Hare Intl per day. You should also have plenty of airline options to choose from since 2 airlines have flights to the Knoxville airport from Chicago O'Hare Intl. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Chicago O'Hare Intl Airport to Knoxville?

    There are many flights that can get you from Chicago O'Hare Intl Airport to Knoxville in 1h 42m. Fly via United Airlines to get the fastest option. Chicago O'Hare Intl Airport and Knoxville are separated by a distance of 475 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Knoxville round-trip?

    American Airlines, at $189, was found to be the cheapest airline from Chicago O'Hare Intl Airport to Knoxville. An alternate airline flying to your destination would be United Airlines. You may be able to fly from Chicago O'Hare Intl Airport to Knoxville for 39% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Knoxville one-way?

    One-way options have recently been found by users for as low as $128 on American Airlines. Other airlines that offer cheap prices include United Airlines from $128 and Delta from $283 one-way.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Knoxville?

    Consider Republic Airways (100%), Envoy Air (94%) or British Airways (63%) when booking your flight. These represent the most reliable airlines when flying from Chicago O'Hare Intl Airport to Knoxville.

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Knoxville?

    Looking for the cheapest flight from Chicago O'Hare Intl Airport to Knoxville? While on average our users pay $303, our data indicates the cheapest price to be $128. The most popular route (Chicago O'Hare Intl - Knoxville McGhee Tyson), is priced around $189.

  • Can I find deals for flights from O'Hare Intl to Knoxville that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Knoxville.

  • Can I find deals for business class flights from O'Hare Intl to Knoxville?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?

    Currently, April is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $179). Flying from Chicago O'Hare Intl Airport to Knoxville in September is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 2 airlines flying from O'Hare Intl to Knoxville

Discover the top 2 airlines that operate flights from O'Hare Intl to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$189Average$302FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$193Average$330FlexibilityNo cancel feeOn-time69%

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