$117+ Cheap flights from Charleston to Knoxville (CHS - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — TYS
Aug 17 — Aug 241
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Knoxville
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Best
Last-minute
One-way
Cheapest flights from Charleston to KnoxvilleExplore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
Explore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:26 am
CHS
- TYS
1 stop5h 31m
American Airlines
Tue 8/186:05 pm
TYS
- CHS
1 stop4h 55m
American Airlines
Deal found 7/13![American Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:47 pm
CHS
- TYS
1 stop12h 49m
Multiple Airlines
Thu 8/2012:55 pm
TYS
- CHS
2 stops29h 16m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$263
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:15 am
CHS
- TYS
1 stop4h 56m
Delta
Thu 8/275:40 am
TYS
- CHS
1 stop3h 18m
Delta
Deal found 7/15![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:45 am
CHS
- TYS
1 stop5h 20m
Southwest
Tue 8/187:00 am
TYS
- CHS
2 stops12h 15m
Southwest
Deal found 7/13![Southwest logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:57 pm
CHS
- TYS
1 stop17h 17m
Multiple Airlines
Sun 9/135:38 pm
TYS
- CHS
1 stop15h 10m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:12 am
CHS
- TYS
1 stop5h 19m
American Airlines
Thu 8/136:05 pm
TYS
- CHS
1 stop4h 55m
American Airlines
Deal found 7/15![American Airlines logo]()
$305
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 am
CHS
- TYS
2 stops12h 55m
Southwest
Sun 9/138:30 am
TYS
- CHS
1 stop10h 25m
Southwest
Deal found 7/17![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:10 am
CHS
- TYS
2 stops10h 45m
Southwest
Wed 8/197:00 am
TYS
- CHS
2 stops12h 15m
Southwest
Deal found 7/15![Southwest logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:23 pm
CHS
- TYS
1 stop7h 21m
Multiple Airlines
Thu 8/138:29 pm
TYS
- CHS
2 stops18h 15m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$313
Best flights from Charleston to KnoxvilleDiscover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
Discover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:47 pm
CHS
- TYS
1 stop12h 49m
Multiple Airlines
Thu 8/2012:55 pm
TYS
- CHS
2 stops29h 16m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$263
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:11 am
CHS
- TYS
1 stop3h 29m
Delta
Sun 9/137:50 am
TYS
- CHS
1 stop5h 15m
Delta
Deal found 7/17![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 am
CHS
- TYS
2 stops12h 55m
Southwest
Sun 9/138:30 am
TYS
- CHS
1 stop10h 25m
Southwest
Deal found 7/17![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:14 am
CHS
- TYS
1 stop13h 45m
United Airlines
Mon 8/175:45 am
TYS
- CHS
1 stop9h 25m
United Airlines
Deal found 7/14![United Airlines logo]()
$511
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:15 am
CHS
- TYS
1 stop4h 56m
Delta
Thu 8/275:40 am
TYS
- CHS
1 stop3h 18m
Delta
Deal found 7/18![Delta logo]()
$298
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:01 pm
CHS
- TYS
1 stop4h 18m
Delta
Mon 9/712:01 pm
TYS
- CHS
1 stop5h 37m
Delta
Deal found 7/18![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:35 am
CHS
- TYS
1 stop5h 35m
Southwest
Mon 11/98:10 am
TYS
- CHS
1 stop5h 10m
Southwest
Deal found 7/15![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:40 am
CHS
- TYS
2 stops9h 55m
Southwest
Fri 8/218:25 am
TYS
- CHS
2 stops10h 45m
Southwest
Deal found 7/15![Southwest logo]()
$415
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:35 am
CHS
- TYS
1 stop5h 30m
Southwest
Thu 8/67:10 am
TYS
- CHS
2 stops11h 25m
Southwest
Deal found 7/18![Southwest logo]()
$498
Last-minute flights from Charleston to KnoxvilleDiscover last-minute flight deals from Charleston to Knoxville. Data last updated July 18, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Knoxville. Data last updated July 18, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:12 am
CHS
- TYS
1 stop5h 19m
American Airlines
Thu 8/136:05 pm
TYS
- CHS
1 stop4h 55m
American Airlines
Deal found 7/15![American Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:23 pm
CHS
- TYS
1 stop7h 21m
Multiple Airlines
Thu 8/138:29 pm
TYS
- CHS
2 stops18h 15m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:40 am
CHS
- TYS
2 stops9h 55m
Southwest
Thu 8/137:10 am
TYS
- CHS
2 stops11h 25m
Southwest
Deal found 7/14![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:26 am
CHS
- TYS
1 stop5h 31m
American Airlines
Tue 8/186:05 pm
TYS
- CHS
1 stop4h 55m
American Airlines
Deal found 7/13![American Airlines logo]()
$233
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:45 am
CHS
- TYS
1 stop5h 20m
Southwest
Tue 8/187:00 am
TYS
- CHS
2 stops12h 15m
Southwest
Deal found 7/13![Southwest logo]()
$287
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:10 am
CHS
- TYS
2 stops10h 45m
Southwest
Wed 8/197:00 am
TYS
- CHS
2 stops12h 15m
Southwest
Deal found 7/15![Southwest logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:47 pm
CHS
- TYS
1 stop12h 49m
Multiple Airlines
Thu 8/2012:55 pm
TYS
- CHS
2 stops29h 16m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:23 pm
CHS
- TYS
1 stop7h 21m
Multiple Airlines
Fri 8/212:51 pm
TYS
- CHS
1 stop17h 57m
Multiple Airlines
Deal found 7/15![Multiple Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:15 am
CHS
- TYS
1 stop4h 56m
Delta
Thu 8/275:40 am
TYS
- CHS
1 stop3h 18m
Delta
Deal found 7/15![Delta logo]()
$285
One-way flights from Charleston to KnoxvilleSearch for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
Search for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:15 am
CHS
- TYS
1 stop3h 28m
American Airlines
Deal found 7/15![American Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:05 pm
CHS
- TYS
1 stop12h 30m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:56 pm
CHS
- TYS
2 stops39h 50m
Multiple Airlines
Deal found 7/15![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:39 pm
CHS
- TYS
2 stops36h 35m
Multiple Airlines
Deal found 7/15![Multiple Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:56 pm
CHS
- TYS
2 stops39h 50m
Multiple Airlines
Deal found 7/15![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:25 am
CHS
- TYS
2 stops30h 51m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$205
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:00 am
CHS
- TYS
1 stop3h 31m
American Airlines
Deal found 7/15![American Airlines logo]()
$219
Find flight deals from Charleston to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $233 (Delta) |
One-way from | $117 (American Airlines) |
Popular in | August |
Cheapest in | January |
Average price | $385 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Thu 8/13
7:47 pm-8:36 am
1 stop12h 49m
Knoxville McGhee Tyson
Thu 8/20
12:55 pm-6:11 pm
2 stops29h 16m
$263
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Fri 9/11
11:11 am-2:40 pm
1 stop3h 29m
Knoxville McGhee Tyson
Sun 9/13
7:50 am-1:05 pm
1 stop5h 15m
$285
Quickest round-trip
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sun 8/23
6:15 am-11:11 am
1 stop4h 56m
Knoxville McGhee Tyson
Thu 8/27
5:40 am-8:58 am
1 stop3h 18m
$298
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Fri 9/11
7:00 am-7:55 pm
2 stops12h 55m
Knoxville McGhee Tyson
Sun 9/13
8:30 am-6:55 pm
1 stop10h 25m
$311
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Fri 9/4
1:01 pm-5:19 pm
1 stop4h 18m
Knoxville McGhee Tyson
Mon 9/7
12:01 pm-5:38 pm
1 stop5h 37m
$337
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Fri 11/6
6:35 am-12:10 pm
1 stop5h 35m
Knoxville McGhee Tyson
Mon 11/9
8:10 am-1:20 pm
1 stop5h 10m
$373
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Fri 8/14
8:40 am-6:35 pm
2 stops9h 55m
Knoxville McGhee Tyson
Fri 8/21
8:25 am-7:10 pm
2 stops10h 45m
$415
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sun 8/2
6:35 am-12:05 pm
1 stop5h 30m
Knoxville McGhee Tyson
Thu 8/6
7:10 am-6:35 pm
2 stops11h 25m
$498
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Thu 8/13
10:14 am-11:59 pm
1 stop13h 45m
Knoxville McGhee Tyson
Mon 8/17
5:45 am-3:10 pm
1 stop9h 25m
$511
Cheapest one-way
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Thu 9/10
8:35 am-2:40 pm
1 stop6h 05m
$117
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Charleston to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Knoxville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Charleston with our price prediction graph.
CHS-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 18, 2026.
Read reviews from past customers who have flown Delta from Charleston to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charleston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 18, 2026.
Charleston and Knoxville flights
Browse other Charleston and Knoxville flight options. Last updated on July 18, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on July 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Charleston to Knoxville
Discover the top airline that operate flights from Charleston to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$508 | FlexibilityNo cancel fee | On-timeN/A |