$141+ Cheap flights from Charleston to Knoxville (CHS - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — TYS
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Knoxville
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Best
Last-minute
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Cheapest flights from Charleston to KnoxvilleExplore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:25 am
CHS
- TYS
1 stop5h 54m
Delta
Thu 8/275:40 am
TYS
- CHS
1 stop4h 40m
Delta
Deal found 7/23![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:10 am
CHS
- TYS
2 stops10h 45m
Southwest
Tue 9/17:00 am
TYS
- CHS
1 stop5h 50m
Southwest
Deal found 7/26![Southwest logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:23 pm
CHS
- TYS
1 stop7h 21m
Multiple Airlines
Mon 8/176:29 pm
TYS
- CHS
1 stop14h 09m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:04 pm
CHS
- TYS
2 stops42h 00m
Multiple Airlines
Tue 9/153:21 pm
TYS
- CHS
1 stop22h 03m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$276
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:00 pm
CHS
- TYS
1 stop5h 40m
Southwest
Mon 11/97:25 pm
TYS
- CHS
2 stops14h 55m
Southwest
Deal found 7/28![Southwest logo]()
$282
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:06 pm
CHS
- TYS
1 stop3h 28m
American Airlines
Sun 8/305:00 am
TYS
- CHS
1 stop5h 17m
American Airlines
Deal found 7/24![American Airlines logo]()
$290
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:35 am
CHS
- TYS
1 stop5h 40m
Southwest
Sun 11/18:10 am
TYS
- CHS
1 stop5h 10m
Southwest
Deal found 7/24![Southwest logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:15 am
CHS
- TYS
1 stop24h 51m
Multiple Airlines
Sat 8/155:03 pm
TYS
- CHS
1 stop20h 01m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:47 pm
CHS
- TYS
1 stop22h 17m
Multiple Airlines
Thu 8/2712:55 pm
TYS
- CHS
2 stops29h 16m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$298
Best flights from Charleston to KnoxvilleDiscover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:25 am
CHS
- TYS
1 stop5h 54m
Delta
Thu 8/275:40 am
TYS
- CHS
1 stop4h 40m
Delta
Deal found 7/23![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:10 am
CHS
- TYS
2 stops10h 45m
Southwest
Tue 9/17:00 am
TYS
- CHS
1 stop5h 50m
Southwest
Deal found 7/26![Southwest logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:47 pm
CHS
- TYS
1 stop22h 17m
Multiple Airlines
Thu 8/2712:55 pm
TYS
- CHS
2 stops29h 16m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:45 pm
CHS
- TYS
1 stop5h 07m
Delta
Tue 9/14:38 pm
TYS
- CHS
1 stop5h 04m
Delta
Deal found 7/26![Delta logo]()
$233
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:51 pm
CHS
- TYS
1 stop14h 46m
United Airlines
Sat 8/155:45 am
TYS
- CHS
1 stop9h 25m
United Airlines
Deal found 7/25![United Airlines logo]()
$613
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:10 am
CHS
- TYS
2 stops10h 50m
Southwest
Tue 9/158:05 am
TYS
- CHS
2 stops11h 45m
Southwest
Deal found 7/28![Southwest logo]()
$326
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:35 am
CHS
- TYS
2 stops13h 20m
Southwest
Thu 8/277:10 am
TYS
- CHS
2 stops11h 25m
Southwest
Deal found 7/23![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:35 am
CHS
- TYS
1 stop5h 45m
Southwest
Fri 8/287:10 am
TYS
- CHS
2 stops11h 25m
Southwest
Deal found 7/24![Southwest logo]()
$378
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:45 pm
CHS
- TYS
1 stop3h 15m
Delta
Thu 8/135:40 am
TYS
- CHS
1 stop4h 40m
Delta
Deal found 7/25![Delta logo]()
$447
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:00 pm
CHS
- TYS
2 stops17h 16m
Multiple Airlines
Mon 8/37:20 pm
TYS
- CHS
1 stop13h 18m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$542
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:30 am
CHS
- TYS
2 stops16h 35m
Multiple Airlines
Sun 10/189:25 am
TYS
- CHS
1 stop6h 38m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$598
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:35 am
CHS
- TYS
1 stop5h 30m
Southwest
Mon 8/37:30 am
TYS
- CHS
1 stop5h 45m
Southwest
Deal found 7/23![Southwest logo]()
$567
Last-minute flights from Charleston to KnoxvilleDiscover last-minute flight deals from Charleston to Knoxville. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Knoxville. Data last updated July 28, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:47 pm
CHS
- TYS
1 stop12h 49m
Multiple Airlines
Thu 8/138:29 pm
TYS
- CHS
2 stops18h 15m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:23 pm
CHS
- TYS
1 stop7h 21m
Multiple Airlines
Mon 8/176:29 pm
TYS
- CHS
1 stop14h 09m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:15 am
CHS
- TYS
1 stop24h 51m
Multiple Airlines
Sat 8/155:03 pm
TYS
- CHS
1 stop20h 01m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:25 am
CHS
- TYS
1 stop5h 54m
Delta
Thu 8/275:40 am
TYS
- CHS
1 stop4h 40m
Delta
Deal found 7/23![Delta logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:47 pm
CHS
- TYS
1 stop22h 17m
Multiple Airlines
Thu 8/2712:55 pm
TYS
- CHS
2 stops29h 16m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:15 am
CHS
- TYS
1 stop5h 29m
American Airlines
Sun 8/236:05 pm
TYS
- CHS
1 stop5h 54m
American Airlines
Deal found 7/27![American Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:10 am
CHS
- TYS
2 stops10h 45m
Southwest
Tue 9/17:00 am
TYS
- CHS
1 stop5h 50m
Southwest
Deal found 7/26![Southwest logo]()
$238
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:06 pm
CHS
- TYS
1 stop3h 28m
American Airlines
Sun 8/305:00 am
TYS
- CHS
1 stop5h 17m
American Airlines
Deal found 7/24![American Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:15 am
CHS
- TYS
1 stop4h 56m
Delta
Sun 8/305:40 am
TYS
- CHS
1 stop4h 40m
Delta
Deal found 7/27![Delta logo]()
$328
One-way flights from Charleston to KnoxvilleSearch for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:53 pm
CHS
- TYS
1 stop28h 10m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:47 pm
CHS
- TYS
1 stop12h 49m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$197
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:25 am
CHS
- TYS
1 stop5h 35m
Southwest
Deal found 7/27![Southwest logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:37 pm
CHS
- TYS
3 stops22h 13m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$398
Find flight deals from Charleston to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $233 (Delta) |
One-way from | $141 (Kiwi.com) |
Popular in | August |
Cheapest in | January |
Average price | $547 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Thu 8/20
11:25 am-5:19 pm
1 stop5h 54m
Knoxville McGhee Tyson
Thu 8/27
5:40 am-10:20 am
1 stop4h 40m
$233
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Tue 8/25
6:45 pm-11:52 pm
1 stop5h 07m
Knoxville McGhee Tyson
Tue 9/1
4:38 pm-9:42 pm
1 stop5h 04m
$233
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Tue 8/25
8:10 am-6:55 pm
2 stops10h 45m
Knoxville McGhee Tyson
Tue 9/1
7:00 am-12:50 pm
1 stop5h 50m
$238
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Thu 8/20
7:47 pm-6:04 pm
1 stop22h 17m
Knoxville McGhee Tyson
Thu 8/27
12:55 pm-6:11 pm
2 stops29h 16m
$298
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Tue 9/8
8:10 am-7:00 pm
2 stops10h 50m
Knoxville McGhee Tyson
Tue 9/15
8:05 am-7:50 pm
2 stops11h 45m
$326
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Thu 8/20
6:35 am-7:55 pm
2 stops13h 20m
Knoxville McGhee Tyson
Thu 8/27
7:10 am-6:35 pm
2 stops11h 25m
$362
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Fri 8/21
6:35 am-12:20 pm
1 stop5h 45m
Knoxville McGhee Tyson
Fri 8/28
7:10 am-6:35 pm
2 stops11h 25m
$378
Quickest round-trip
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sun 8/9
6:45 pm-10:00 pm
1 stop3h 15m
Knoxville McGhee Tyson
Thu 8/13
5:40 am-10:20 am
1 stop4h 40m
$447
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sun 8/2
9:00 pm-2:16 pm
2 stops17h 16m
Knoxville McGhee Tyson
Mon 8/3
7:20 pm-8:38 am
1 stop13h 18m
$542
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sun 8/2
6:35 am-12:05 pm
1 stop5h 30m
Knoxville McGhee Tyson
Mon 8/3
7:30 am-1:15 pm
1 stop5h 45m
$567
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Charleston to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Knoxville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Charleston with our price prediction graph.
CHS-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 28, 2026.
Read reviews from past customers who have flown Delta from Charleston to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charleston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Charleston and Knoxville flights
Browse other Charleston and Knoxville flight options. Last updated on July 28, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Charleston to Knoxville
Discover the top airline that operate flights from Charleston to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$508 | FlexibilityNo cancel fee | On-timeN/A |