$137+ Cheap flights from Charleston to Knoxville (CHS - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — TYS
Sep 26 — Oct 31
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Charleston to KnoxvilleExplore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.
Explore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:41 pm -
1 stop3h 58m
Sun 9/67:30 am -
1 stop6h 22m
Deal found 8/25![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:25 pm -
1 stop6h 30m
Sat 9/126:50 am -
2 stops11h 25m
Deal found 8/26![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:45 pm -
1 stop4h 45m
Mon 11/27:25 pm -
2 stops14h 55m
Deal found 8/25![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:25 am -
1 stop4h 04m
Tue 10/65:40 am -
1 stop3h 12m
Deal found 8/22![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:05 pm -
1 stop4h 54m
Sun 10/255:40 am -
1 stop4h 30m
Deal found 8/24![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:45 am -
1 stop5h 20m
Tue 9/298:05 am -
2 stops11h 45m
Deal found 8/25![Southwest logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:43 pm -
1 stop17h 21m
Fri 9/111:54 pm -
2 stops18h 44m
Deal found 8/25![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:13 pm -
1 stop9h 23m
Sun 10/186:40 am -
1 stop26h 08m
Deal found 8/25![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:53 pm -
1 stop28h 10m
Wed 9/23:46 pm -
1 stop21h 18m
Deal found 8/24![Multiple Airlines logo]()
$354
Best flights from Charleston to KnoxvilleDiscover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.
Discover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:26 pm -
1 stop4h 01m
Sat 9/125:40 am -
1 stop3h 54m
Deal found 8/26![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:25 pm -
1 stop6h 30m
Sat 9/126:50 am -
2 stops11h 25m
Deal found 8/26![Southwest logo]()
$278
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:52 pm -
1 stop9h 07m
Sat 10/315:45 am -
1 stop8h 38m
Deal found 8/26![United Airlines logo]()
$519
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:25 am -
1 stop4h 04m
Tue 10/65:40 am -
1 stop3h 12m
Deal found 8/22![Delta logo]()
$310
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:45 pm -
2 stops5h 55m
Mon 11/27:25 pm -
2 stops14h 55m
Deal found 8/25![Southwest logo]()
$326
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:10 am -
2 stops10h 50m
Tue 9/298:05 am -
2 stops11h 45m
Deal found 8/25![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:26 pm -
1 stop4h 01m
Sun 9/205:40 am -
1 stop4h 28m
Deal found 8/23![Delta logo]()
$356
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:50 am -
1 stop4h 41m
Sun 11/812:06 pm -
1 stop5h 49m
Deal found 8/23![Delta logo]()
$413
Last-minute flights from Charleston to KnoxvilleDiscover last-minute flight deals from Charleston to Knoxville. Data last updated August 27, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Knoxville. Data last updated August 27, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:53 pm -
1 stop28h 10m
Wed 9/23:46 pm -
1 stop21h 18m
Deal found 8/24![Multiple Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:41 pm -
1 stop3h 58m
Sun 9/67:30 am -
1 stop6h 22m
Deal found 8/25![Delta logo]()
$273
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:07 am -
1 stop4h 06m
Mon 9/75:15 am -
1 stop4h 24m
Deal found 8/26![American Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:25 pm -
1 stop6h 30m
Sat 9/126:50 am -
2 stops11h 25m
Deal found 8/26![Southwest logo]()
$278
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:06 pm -
1 stop3h 25m
Sun 9/134:51 pm -
1 stop5h 05m
Deal found 8/25![American Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
2 stops28h 04m
Sun 9/135:44 pm -
1 stop27h 12m
Deal found 8/25![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:43 pm -
1 stop17h 21m
Fri 9/111:54 pm -
2 stops18h 44m
Deal found 8/25![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:13 pm -
1 stop22h 28m
Sat 9/126:55 pm -
2 stops20h 12m
Deal found 8/25![Multiple Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:26 pm -
1 stop4h 01m
Sun 9/205:40 am -
1 stop4h 28m
Deal found 8/23![Delta logo]()
$356
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:45 am -
1 stop5h 20m
Tue 9/298:05 am -
2 stops11h 45m
Deal found 8/25![Southwest logo]()
$327
One-way flights from Charleston to KnoxvilleSearch for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.
Search for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:50 am -
1 stop3h 04m
Deal found 8/25![Delta logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:57 pm -
1 stop15h 38m
Deal found 8/23![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:21 pm -
2 stops20h 44m
Deal found 8/26![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:13 pm -
1 stop22h 28m
Deal found 8/23![Multiple Airlines logo]()
$199
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:05 pm -
1 stop4h 54m
Deal found 8/24![Delta logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:25 am -
2 stops13h 26m
Deal found 8/22![Multiple Airlines logo]()
$213
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:07 pm -
1 stop4h 28m
Deal found 8/22![American Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:58 pm -
3 stops44h 23m
Deal found 8/24![Multiple Airlines logo]()
$232
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:40 am -
2 stops13h 25m
Deal found 8/25![Southwest logo]()
$235
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:25 pm -
2 stops9h 15m
Deal found 8/24![Southwest logo]()
$239
Find flight deals from Charleston to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $273 (Delta) |
One-way from | $137 (Delta) |
Popular in | August |
Cheapest in | January |
Average price | $979 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 27, 2026.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Wed 9/9
6:26 pm-10:27 pm
1 stop4h 01m
Knoxville McGhee Tyson
Sat 9/12
5:40 am-9:34 am
1 stop3h 54m
$273
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Wed 9/9
1:25 pm-7:55 pm
1 stop6h 30m
Knoxville McGhee Tyson
Sat 9/12
6:50 am-6:15 pm
2 stops11h 25m
$278
Quickest round-trip
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Sun 10/4
5:25 am-9:29 am
1 stop4h 04m
Knoxville McGhee Tyson
Tue 10/6
5:40 am-8:52 am
1 stop3h 12m
$310
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Fri 10/30
4:45 pm-10:40 pm
2 stops5h 55m
Knoxville McGhee Tyson
Mon 11/2
7:25 pm-10:20 am
2 stops14h 55m
$326
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Tue 9/22
8:10 am-7:00 pm
2 stops10h 50m
Knoxville McGhee Tyson
Tue 9/29
8:05 am-7:50 pm
2 stops11h 45m
$332
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Sat 9/19
6:26 pm-10:27 pm
1 stop4h 01m
Knoxville McGhee Tyson
Sun 9/20
5:40 am-10:08 am
1 stop4h 28m
$356
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Thu 11/5
8:50 am-1:31 pm
1 stop4h 41m
Knoxville McGhee Tyson
Sun 11/8
12:06 pm-5:55 pm
1 stop5h 49m
$413
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Wed 10/28
2:52 pm-11:59 pm
1 stop9h 07m
Knoxville McGhee Tyson
Sat 10/31
5:45 am-2:23 pm
1 stop8h 38m
$519
Cheapest one-way
Quickest one-way
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Tue 10/6
7:50 am-10:54 am
1 stop3h 04m
$137
CharlestonKnoxville
CHS Charleston - TYS Knoxville McGhee Tyson
CHSTYS
Charleston
Fri 10/2
4:57 pm-8:35 am
1 stop15h 38m
$148
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Charleston to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Knoxville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Charleston with our price prediction graph.
CHS-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Knoxville
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 27, 2026.
Read reviews from past customers who have flown Delta from Charleston to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Charleston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 27, 2026.
Charleston and Knoxville flights
Browse other Charleston and Knoxville flight options. Last updated on August 27, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on August 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Charleston to Knoxville
Discover the top airline that operate flights from Charleston to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$508 | FlexibilityNo cancel fee | On-timeN/A |