HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$117+ Cheap flights from Charleston to Knoxville (CHS - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — TYS
ago. 1 — ago. 81
sáb. 8/1
sáb. 8/8
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Knoxville

Cheapest flights from Charleston to Knoxville
Explore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 2, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/137:47 pm
CHS
-
TYS
1 stop12h 49m
Multiple Airlines
lun. 8/176:29 pm
TYS
-
CHS
1 stop14h 09m
Multiple Airlines
Deal found 6/28$216
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/286:41 am
CHS
-
TYS
1 stop3h 57m
American Airlines
mar. 8/411:03 am
TYS
-
CHS
1 stop3h 38m
American Airlines
Deal found 6/30$233
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/286:35 am
CHS
-
TYS
2 stops10h 25m
Southwest
mar. 8/47:00 am
TYS
-
CHS
1 stop5h 50m
Southwest
Deal found 6/30$238
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/33:23 pm
CHS
-
TYS
1 stop8h 10m
Multiple Airlines
mié. 8/52:25 pm
TYS
-
CHS
1 stop18h 13m
Multiple Airlines
Deal found 6/30$239
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/116:15 am
CHS
-
TYS
1 stop5h 29m
American Airlines
jue. 8/137:25 pm
TYS
-
CHS
1 stop3h 35m
American Airlines
Deal found 7/1$246
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/152:06 pm
CHS
-
TYS
1 stop3h 28m
American Airlines
lun. 8/177:25 pm
TYS
-
CHS
1 stop3h 35m
American Airlines
Deal found 6/30$247
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/118:10 am
CHS
-
TYS
2 stops10h 45m
Southwest
jue. 8/137:10 am
TYS
-
CHS
1 stop9h 30m
Southwest
Deal found 7/1$257

Find flight deals from Charleston to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$216
(Kiwi.com)

One-way from

$117
(American Airlines)

Popular in

August

Cheapest in

January

Average price

$385
Provider with most accurate pricing for Charleston-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Knoxville McGhee Tyson flights.
Search Deals
From Charleston to Knoxville McGhee Tyson
Search Deals
One-way flight from Charleston to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($123 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 2, 2026.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

jue. 8/13

7:47 pm-8:36 am

1 stop12h 49m

Knoxville McGhee Tyson

lun. 8/17

6:29 pm-8:38 am

1 stop14h 09m

$216
Quickest round-trip

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

sáb. 8/15

2:06 pm-5:34 pm

1 stop3h 28m

Knoxville McGhee Tyson

lun. 8/17

7:25 pm-11:00 pm

1 stop3h 35m

$247

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

mar. 8/11

8:10 am-6:55 pm

2 stops10h 45m

Knoxville McGhee Tyson

jue. 8/13

7:10 am-4:40 pm

1 stop9h 30m

$257

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

jue. 8/13

6:11 am-9:43 am

1 stop3h 32m

Knoxville McGhee Tyson

lun. 8/17

5:15 am-9:39 am

1 stop4h 24m

$259

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

lun. 8/10

6:35 am-5:10 pm

2 stops10h 35m

Knoxville McGhee Tyson

vie. 8/14

7:10 am-6:35 pm

2 stops11h 25m

$320

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

jue. 8/13

6:35 am-5:10 pm

2 stops10h 35m

Knoxville McGhee Tyson

lun. 8/17

8:25 am-3:25 pm

1 stop7h 00m

$323

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

vie. 9/4

6:45 pm-11:52 pm

1 stop5h 07m

Knoxville McGhee Tyson

lun. 9/7

5:40 am-10:08 am

1 stop4h 28m

$369
Cheapest one-way

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

mar. 9/15

7:35 am-7:50 pm

2 stops12h 15m

$122
Quickest one-way

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

dom. 8/2

7:50 pm-11:51 pm

1 stop4h 01m

$169

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

dom. 8/2

2:53 pm-4:42 pm

3 stops25h 49m

$180

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Charleston to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Knoxville in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated julio 2, 2026.
Read reviews from past customers who have flown Delta from Charleston to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,452 reviews

Comfort

7.8

Food

7.2

Boarding

8.1

Overall

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,452 reviews
Delta
7.8
Good
8,452 reviews

Comfort

7.8

Food

7.2

Boarding

8.1

Overall

7.8

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Charleston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Knoxville?

    Airlines like American Airlines and Southwest fly from Charleston to Knoxville in about 3h 28m. The time it takes to get you to your destination can typically vary by up to 7h 17m. The distance between Charleston and Knoxville is about 302 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Charleston to Knoxville round-trip?

    Flying on Delta is currently your cheapest option to Knoxville, with prices starting at $254. You may be able to fly from Charleston to Knoxville for 53% less than the average price by searching for this airline.

  • Can I find deals for flights from Charleston to Knoxville that include hotel bookings?

    Yes. In addition to deals on Charleston to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Knoxville.

  • Can I find deals for business class flights from Charleston to Knoxville?

    Yes. Cheapflights offers flight deals from Charleston to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Charleston to Knoxville

Discover the top airline that operate flights from Charleston to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$254Average$498FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.