HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$107+ Cheap flights from Charleston to Knoxville (CHS - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — TYS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$246
(Mytrip)

One-way from

$107
(Mytrip)

Popular in

August

Cheapest in

June

Average price

$356
From Charleston to Knoxville McGhee Tyson
Search Deals
One-way flight from Charleston to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Charleston to Knoxville

Cheapest flights from Charleston to Knoxville
Explore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1010:53 amCHS - TYS
2 stops21h 09mMultiple Airlines
Sat 7/128:10 amTYS - CHS
2 stops12h 43mMultiple Airlines
Deal found 6/10$263
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/73:26 pmCHS - TYS
2 stops30h 49mAllegiant Air
Sat 8/99:00 amTYS - CHS
2 stops29h 36mAllegiant Air
Deal found 6/11$307
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/237:30 amCHS - TYS
1 stop3h 38mDelta
Wed 7/305:30 amTYS - CHS
1 stop3h 16mDelta
Deal found 6/11$347
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/256:00 amCHS - TYS
1 stop10h 57mAmerican Airlines
Sun 8/316:49 amTYS - CHS
1 stop12h 14mAmerican Airlines
Deal found 6/11$354
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:45 pmCHS - TYS
1 stop15h 03mUnited Airlines
Mon 11/177:20 pmTYS - CHS
2 stops15h 09mUnited Airlines
Deal found 6/10$481

Cheapflights Fare Finder

Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.

Fly from

Charleston

Fly to

Knoxville

Route

Depart

Return

Price

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Thu 7/10

10:53 am-8:02 am

2 stops21h 09m

Knoxville McGhee Tyson

Sat 7/12

8:10 am-8:53 pm

2 stops12h 43m

$263

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Thu 8/7

3:26 pm-10:15 pm

2 stops30h 49m

Knoxville McGhee Tyson

Sat 8/9

9:00 am-2:36 pm

2 stops29h 36m

$307

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Wed 7/23

7:30 am-11:08 am

1 stop3h 38m

Knoxville McGhee Tyson

Wed 7/30

5:30 am-8:46 am

1 stop3h 16m

$347

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Mon 8/25

6:00 am-4:57 pm

1 stop10h 57m

Knoxville McGhee Tyson

Sun 8/31

6:49 am-7:03 pm

1 stop12h 14m

$354

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Fri 11/14

7:45 pm-10:48 am

1 stop15h 03m

Knoxville McGhee Tyson

Mon 11/17

7:20 pm-10:29 am

2 stops15h 09m

$481

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Sat 7/26

9:48 pm-8:04 pm

1 stop22h 16m

$107

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Sat 7/26

8:56 am-8:04 pm

2 stops35h 08m

$136

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Tue 8/12

6:00 am-4:57 pm

1 stop10h 57m

$202

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Tue 6/17

6:20 am-9:53 am

1 stop3h 33m

$246

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

Tue 8/12

7:40 pm-1:21 pm

2 stops17h 41m

$342

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Charleston to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Knoxville

What is the cheapest month to book a flight from Charleston to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Charleston to Knoxville (average of $296). Flying from Charleston to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to TYS?

Find hourly flight availability from Charleston to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Charleston to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 25% versus a flight at noon.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.3
Good
725 reviews
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Charleston to Knoxville round-trip?

    Flying on Allegiant Air is currently your cheapest option to Knoxville, with prices starting at $307. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $347 and $359, respectively. You may be able to fly from Charleston to Knoxville for 42% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Charleston to Knoxville one-way?

    The cheapest airlines for a one-way flight from Charleston to Knoxville are Allegiant Air ($136), American Airlines ($202), and Delta ($246).

  • Can I find deals for flights from Charleston to Knoxville that include hotel bookings?

    Yes. In addition to deals on Charleston to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Knoxville.

  • Can I find deals for business class flights from Charleston to Knoxville?

    Yes. Cheapflights offers flight deals from Charleston to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Charleston to Knoxville (average of $296). Flying from Charleston to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Nashville flights
Greenville to Nashville flights
Charleston to Nashville flights
Charlotte to Memphis flights
Savannah to Nashville flights
Myrtle Beach to Nashville flights
Columbia to Nashville flights
Charlotte to Chattanooga flights
Charleston to Memphis flights
Charlotte to Knoxville flights
Columbia to Memphis flights
Savannah to Knoxville flights
Greenville to Memphis flights
Myrtle Beach to Knoxville flights
Augusta to Nashville flights
Hilton Head Island to Nashville flights
Myrtle Beach to Memphis flights
Augusta to Memphis flights
Savannah to Chattanooga flights
Florence to Nashville flights
Columbia to Chattanooga flights
Charleston to Chattanooga flights
Savannah to Memphis flights
Hilton Head Island to Knoxville flights

Top 2 airlines flying from Charleston to Knoxville

Discover the top 2 airlines that operate flights from Charleston to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$346Average$507FlexibilityNo cancel feeOn-time71%
DeltaCheapest$356Average$588FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.