$141+ Cheap flights from Charleston to Knoxville (CHS - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — TYS
Jul 2 — Jul 91
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Knoxville
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Best
Last-minute
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Cheapest flights from Charleston to KnoxvilleExplore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 2, 2026.
Explore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/63:23 pm
CHS
- TYS
1 stop8h 10m
Multiple Airlines
Fri 7/107:20 pm
TYS
- CHS
1 stop13h 28m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/293:23 pm
CHS
- TYS
1 stop8h 11m
Multiple Airlines
Mon 7/67:20 pm
TYS
- CHS
1 stop13h 18m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:15 am
CHS
- TYS
1 stop3h 38m
Delta
Tue 7/75:40 am
TYS
- CHS
1 stop3h 21m
Delta
Deal found 6/2![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:00 pm
CHS
- TYS
1 stop6h 15m
Southwest
Tue 7/78:10 am
TYS
- CHS
2 stops12h 20m
Southwest
Deal found 6/1![Southwest logo]()
$300
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:00 am
CHS
- TYS
1 stop6h 40m
Southwest
Tue 9/88:00 am
TYS
- CHS
1 stop4h 35m
Southwest
Deal found 5/30![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:18 am
CHS
- TYS
1 stop5h 58m
Delta
Thu 7/167:49 pm
TYS
- CHS
1 stop3h 30m
Delta
Deal found 6/1![Delta logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:48 pm
CHS
- TYS
2 stops47h 39m
Multiple Airlines
Fri 6/127:00 pm
TYS
- CHS
1 stop20h 28m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:23 pm
CHS
- TYS
1 stop7h 21m
Multiple Airlines
Sun 8/92:56 pm
TYS
- CHS
2 stops23h 48m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$335
Best flights from Charleston to KnoxvilleDiscover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 2, 2026.
Discover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/293:23 pm
CHS
- TYS
1 stop8h 11m
Multiple Airlines
Mon 7/67:20 pm
TYS
- CHS
1 stop13h 18m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:15 am
CHS
- TYS
1 stop3h 38m
Delta
Tue 7/75:40 am
TYS
- CHS
1 stop3h 21m
Delta
Deal found 6/2![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:00 pm
CHS
- TYS
1 stop6h 15m
Southwest
Tue 7/78:10 am
TYS
- CHS
1 stop5h 20m
Southwest
Deal found 6/1![Southwest logo]()
$295
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:51 am
CHS
- TYS
1 stop5h 44m
American Airlines
Fri 6/267:59 pm
TYS
- CHS
1 stop4h 00m
American Airlines
Deal found 5/30![American Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:00 am
CHS
- TYS
1 stop6h 40m
Southwest
Tue 9/88:00 am
TYS
- CHS
1 stop4h 35m
Southwest
Deal found 5/30![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:15 am
CHS
- TYS
1 stop3h 23m
Delta
Sun 7/57:46 pm
TYS
- CHS
1 stop3h 38m
Delta
Deal found 5/29![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/233:00 pm
CHS
- TYS
1 stop6h 15m
Southwest
Fri 6/267:30 am
TYS
- CHS
2 stops8h 05m
Southwest
Deal found 5/30![Southwest logo]()
$341
Last-minute flights from Charleston to KnoxvilleDiscover last-minute flight deals from Charleston to Knoxville. Data last updated June 2, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Knoxville. Data last updated June 2, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:48 pm
CHS
- TYS
2 stops47h 39m
Multiple Airlines
Fri 6/127:00 pm
TYS
- CHS
1 stop20h 28m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/233:00 pm
CHS
- TYS
1 stop6h 15m
Southwest
Thu 6/257:30 am
TYS
- CHS
1 stop5h 45m
Southwest
Deal found 6/1![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:15 am
CHS
- TYS
1 stop3h 23m
Delta
Sun 7/57:46 pm
TYS
- CHS
1 stop3h 38m
Delta
Deal found 5/29![Delta logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/293:23 pm
CHS
- TYS
1 stop8h 11m
Multiple Airlines
Mon 7/67:20 pm
TYS
- CHS
1 stop13h 18m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:15 am
CHS
- TYS
1 stop3h 38m
Delta
Tue 7/75:40 am
TYS
- CHS
1 stop3h 21m
Delta
Deal found 6/2![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:00 pm
CHS
- TYS
1 stop6h 15m
Southwest
Tue 7/78:10 am
TYS
- CHS
2 stops12h 20m
Southwest
Deal found 6/1![Southwest logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/63:23 pm
CHS
- TYS
1 stop8h 10m
Multiple Airlines
Fri 7/107:20 pm
TYS
- CHS
1 stop13h 28m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:18 am
CHS
- TYS
1 stop5h 58m
Delta
Thu 7/167:49 pm
TYS
- CHS
1 stop3h 30m
Delta
Deal found 6/1![Delta logo]()
$316
One-way flights from Charleston to KnoxvilleSearch for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 2, 2026.
Search for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/63:23 pm
CHS
- TYS
1 stop8h 10m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:23 pm
CHS
- TYS
1 stop8h 11m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:05 pm
CHS
- TYS
1 stop21h 49m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$167
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:24 pm
CHS
- TYS
1 stop5h 20m
Delta
Deal found 5/29![Delta logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:34 pm
CHS
- TYS
2 stops44h 12m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$173
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:30 am
CHS
- TYS
2 stops7h 35m
Southwest
Deal found 5/29![Southwest logo]()
$174
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:00 am
CHS
- TYS
2 stops13h 15m
Southwest
Deal found 6/2![Southwest logo]()
$180
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:20 am
CHS
- TYS
1 stop3h 50m
Delta
Deal found 6/1![Delta logo]()
$210
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:00 am
CHS
- TYS
1 stop5h 36m
American Airlines
Deal found 5/30![American Airlines logo]()
$219
Find flight deals from Charleston to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (Kiwi.com) |
One-way from | $141 (Kiwi.com) |
Popular in | August |
Cheapest in | January |
Average price | $400 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Mon 6/29
3:23 pm-11:34 pm
1 stop8h 11m
Knoxville McGhee Tyson
Mon 7/6
7:20 pm-8:38 am
1 stop13h 18m
$271
Quickest round-trip
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Wed 7/1
6:15 am-9:53 am
1 stop3h 38m
Knoxville McGhee Tyson
Tue 7/7
5:40 am-9:01 am
1 stop3h 21m
$295
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Wed 7/1
3:00 pm-9:15 pm
1 stop6h 15m
Knoxville McGhee Tyson
Tue 7/7
8:10 am-1:30 pm
1 stop5h 20m
$295
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sat 9/5
11:00 am-5:40 pm
1 stop6h 40m
Knoxville McGhee Tyson
Tue 9/8
8:00 am-12:35 pm
1 stop4h 35m
$315
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Tue 6/23
6:51 am-12:35 pm
1 stop5h 44m
Knoxville McGhee Tyson
Fri 6/26
7:59 pm-11:59 pm
1 stop4h 00m
$336
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sun 6/28
6:15 am-9:38 am
1 stop3h 23m
Knoxville McGhee Tyson
Sun 7/5
7:46 pm-11:24 pm
1 stop3h 38m
$337
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Tue 6/23
3:00 pm-9:15 pm
1 stop6h 15m
Knoxville McGhee Tyson
Fri 6/26
7:30 am-3:35 pm
2 stops8h 05m
$341
Cheapest one-way
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sat 7/25
6:24 pm-11:44 pm
1 stop5h 20m
$169
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Wed 6/17
4:34 pm-12:46 pm
2 stops44h 12m
$173
CharlestonKnoxville
CHS - TYS
CHSTYS
Charleston
Sat 7/25
6:30 am-2:05 pm
2 stops7h 35m
$174
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Charleston to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Knoxville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Charleston with our price prediction graph.
CHS-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Knoxville
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 2, 2026.
Read reviews from past customers who have flown Delta from Charleston to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Crew
8.5
Boarding
8.1
Overall
7.9
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charleston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 2, 2026.
Charleston and Knoxville flights
Browse other Charleston and Knoxville flight options. Last updated on June 2, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on June 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Charleston to Knoxville
Discover the top airline that operate flights from Charleston to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$526 | FlexibilityNo cancel fee | On-timeN/A |