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Key West

$448+ Cheap flights from Santa Ana, CA to Key West (SNA - EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — EYW
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Santa Ana to Key West

Cheapest flights from Santa Ana to Key West
Explore the most affordable flight options available from Santa Ana to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:45 amSNA - EYW
3 stops25h 35mSpirit Airlines
Sun 1/412:20 pmEYW - SNA
3 stops24h 56mSpirit Airlines
Deal found 12/16$519
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:45 amSNA - EYW
3 stops25h 35mMultiple Airlines
Sun 1/410:37 pmEYW - SNA
2 stops23h 31mMultiple Airlines
Deal found 12/16$525
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:45 amSNA - EYW
2 stops12h 59mAmerican Airlines
Sun 1/42:50 pmEYW - SNA
1 stop9h 01mAmerican Airlines
Deal found 12/16$1,130

Find flight deals from Santa Ana to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$519
(Mytrip)

Popular in

December

Cheapest in

January

Average price

$968
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Key West flight deals.
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Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Key West flights.
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From Santa Ana J. Wayne/Orange Cnty to Key West
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($43 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Santa Ana to Key West that are best for you.

Fly from

Santa Ana

Fly to

Key West

Route

Depart

Return

Price

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 5/16

4:37 pm-11:17 am

2 stops15h 40m

Key West

Tue 5/19

12:15 pm-3:42 pm

3 stops30h 27m

$448

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 5/16

7:51 am-6:23 pm

1 stop7h 32m

Key West

Tue 5/19

3:55 pm-10:08 pm

1 stop9h 13m

$505

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

6:45 am-11:20 am

3 stops25h 35m

Key West

Sun 1/4

12:20 pm-10:16 am

3 stops24h 56m

$519

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

6:45 am-11:20 am

3 stops25h 35m

Key West

Sun 1/4

10:37 pm-7:08 pm

2 stops23h 31m

$525

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 1/1

11:11 am-1:30 pm

2 stops23h 19m

Key West

Mon 1/5

2:30 pm-10:16 am

3 stops22h 46m

$560

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 1/8

4:06 pm-3:17 pm

2 stops20h 11m

Key West

Mon 1/12

4:15 pm-10:24 pm

1 stop9h 09m

$657

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

  • Most accurate provider: When it comes to deals on Santa Ana, California-Key West flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Santa Ana, California-Key West flight deals on Cheapflights vs. Expedia 90-95% of the time. Price accuracy is based on data collected from Santa Ana, California-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana, California-Key West flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Key West

What is the cheapest month to book a flight from Santa Ana, California to Key West?

Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Key West (average of $250). Flying from Santa Ana, California to Key West in June is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated December 18, 2025.
Get a feel of what it's like to fly with American Airlines from Santa Ana to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,054 reviews

Entertainment

6.9

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.5

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
11,054 reviews
American Airlines
7.2
Good
11,054 reviews

Entertainment

6.9

Crew

8.0

Overall

7.2

Boarding

7.5

Food

6.5

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana, California to Key West?

    A quick flight from Santa Ana, California to Key West can take about 7h 32m. Spirit Airlines provides one of the quickest options available for as low as $505. The distance from Santa Ana, California to Key West is about 2254 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Santa Ana, California to Key West round-trip?

    Cheapflights users have booked flights from Santa Ana, California to Key West round-trip from $348. This flight start at 40% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santa Ana to Key West that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Key West.

  • Can I find deals for business class flights from Santa Ana to Key West?

    Yes. Cheapflights offers flight deals from Santa Ana to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Key West?

    Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Key West (average of $250). Flying from Santa Ana, California to Key West in June is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Santa Ana to Key West

Discover the top airline that operate flights from Santa Ana to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$348Average$528FlexibilityNo cancel feeOn-time71%

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