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Key West

$389+ Cheap flights from Santa Ana to Key West (SNA - EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — EYW
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Santa Ana to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$389
(American Airlines)

Popular in

October

Cheapest in

January

Average price

$490
From Santa Ana J. Wayne/Orange Cnty to Key West
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($87 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santa Ana to Key West

Cheapest flights from Santa Ana to Key West
Explore the most affordable flight options available from Santa Ana to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:45 amSNA - EYW
1 stop6h 33mAmerican Airlines
Sat 11/12:32 pmEYW - SNA
1 stop8h 31mAmerican Airlines
Deal found 9/14$389
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:35 amSNA - EYW
2 stops12h 32mAmerican Airlines
Thu 12/181:15 pmEYW - SNA
1 stop11h 11mAmerican Airlines
Deal found 9/14$480
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/58:55 amSNA - EYW
1 stop9h 53mAmerican Airlines
Tue 11/111:33 pmEYW - SNA
2 stops11h 06mAmerican Airlines
Deal found 9/13$491
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:45 amSNA - EYW
2 stops9h 14mAmerican Airlines
Sat 10/41:59 pmEYW - SNA
2 stops10h 21mAmerican Airlines
Deal found 9/15$534

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Santa Ana to Key West that are best for you.

Fly from

Santa Ana

Fly to

Key West

Route

Depart

Return

Price

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 10/25

6:45 am-4:18 pm

1 stop6h 33m

Key West

Sat 11/1

2:32 pm-8:03 pm

1 stop8h 31m

$389

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 11/5

8:55 am-9:48 pm

1 stop9h 53m

Key West

Tue 11/11

1:33 pm-9:39 pm

2 stops11h 06m

$491

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 9/30

6:45 am-6:59 pm

2 stops9h 14m

Key West

Sat 10/4

1:59 pm-9:20 pm

2 stops10h 21m

$534

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

7:45 am-11:07 pm

2 stops12h 22m

Key West

Thu 12/18

1:46 pm-9:48 pm

2 stops11h 02m

$539

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 3/12

7:58 am-6:30 pm

1 stop7h 32m

Key West

Mon 3/16

1:23 pm-9:44 pm

2 stops11h 21m

$600

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 9/27

6:45 am-6:59 pm

2 stops9h 14m

Key West

Wed 10/1

1:59 pm-9:20 pm

2 stops10h 21m

$606

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 9/27

3:45 pm-10:55 am

2 stops16h 10m

Key West

Wed 10/1

7:00 am-12:42 pm

1 stop8h 42m

$612

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Santa Ana to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Key West

What is the cheapest month to book a flight from Santa Ana to Key West?

Currently, August is the cheapest month in which you can book a flight from Santa Ana to Key West (average of $328). Flying from Santa Ana to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated September 15, 2025.
Get a feel of what it's like to fly with American Airlines from Santa Ana to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana to Key West?

    There are many flights that can get you from Santa Ana to Key West in 6h 33m. Fly via American Airlines to get the fastest option. Santa Ana and Key West are separated by a distance of 2254 mi.

  • What is the cheapest airline to fly from Santa Ana to Key West round-trip?

    Currently priced at $308, American Airlines will fly you from Santa Ana to Key West and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. This flight start at 49% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santa Ana to Key West that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Key West.

  • Can I find deals for business class flights from Santa Ana to Key West?

    Yes. Cheapflights offers flight deals from Santa Ana to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana to Key West?

    Currently, August is the cheapest month in which you can book a flight from Santa Ana to Key West (average of $328). Flying from Santa Ana to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Santa Ana to Key West

Discover the top airline that operate flights from Santa Ana to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$308Average$553FlexibilityNo cancel feeOn-time71%

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