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Key West

$389+ Cheap flights from Santa Ana to Key West (SNA - EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — EYW
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
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Cheap flight deals from Santa Ana to Key West

Cheapest flights from Santa Ana to Key West
Explore the most affordable flight options available from Santa Ana to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Gotogate deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/410:48 am
SNA
-
EYW
2 stops21h 42m
Spirit Airlines
Mon 4/132:35 pm
EYW
-
SNA
2 stops22h 18m
Spirit Airlines
Deal found 3/14$389
This Mytrip deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/42:53 pm
SNA
-
EYW
3 stops17h 37m
Spirit Airlines
Tue 4/1412:25 pm
EYW
-
SNA
3 stops36h 20m
Spirit Airlines
Deal found 3/14$500
This Mytrip deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:53 pm
SNA
-
EYW
2 stops17h 37m
Spirit Airlines
Sun 4/512:25 pm
EYW
-
SNA
2 stops24h 28m
Spirit Airlines
Deal found 3/17$581
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:45 am
SNA
-
EYW
2 stops12h 51m
American Airlines
Tue 5/52:29 pm
EYW
-
SNA
1 stop9h 21m
American Airlines
Deal found 3/14$591
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2610:48 am
SNA
-
EYW
3 stops23h 49m
Spirit Airlines
Mon 3/302:35 pm
EYW
-
SNA
3 stops22h 18m
Spirit Airlines
Deal found 3/12$597
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:34 pm
SNA
-
EYW
1 stop14h 40m
Multiple Airlines
Tue 6/91:14 pm
EYW
-
SNA
2 stops28h 14m
Multiple Airlines
Deal found 3/14$612
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/43:29 pm
SNA
-
EYW
1 stop21h 28m
United Airlines
Tue 4/144:38 pm
EYW
-
SNA
1 stop8h 07m
United Airlines
Deal found 3/14$613

Find flight deals from Santa Ana to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 17, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$389
(Gotogate)

Popular in

March

Cheapest in

April

Average price

$997
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Key West flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Key West
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($38 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Santa Ana to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

2:53 pm-11:30 am

2 stops17h 37m

Key West

Sun 4/5

12:25 pm-9:53 am

2 stops24h 28m

$581

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

6:28 pm-3:57 pm

2 stops18h 29m

Key West

Fri 5/1

4:47 pm-9:44 am

2 stops19h 57m

$693

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 4/18

6:28 pm-3:57 pm

2 stops18h 29m

Key West

Wed 4/22

2:35 pm-10:12 pm

1 stop10h 37m

$693
Quickest round-trip

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 6/13

7:42 pm-12:16 pm

2 stops13h 34m

Key West

Tue 6/16

1:01 pm-10:20 pm

2 stops12h 19m

$755
Cheapest one-way
Quickest one-way

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 6/30

7:45 am-7:44 pm

1 stop8h 59m

$410

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/13

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Santa Ana-Key West flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Santa Ana-Key West flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Santa Ana-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana-Key West flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Key West

What is the cheapest month to book a flight from Santa Ana to Key West?

Currently, January is the cheapest month in which you can book a flight from Santa Ana to Key West (average of $250). Flying from Santa Ana to Key West in June is currently the most expensive (average of $483). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated March 17, 2026.
Get a feel of what it's like to fly with American Airlines from Santa Ana to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,468 reviews

Entertainment

6.9

Comfort

7.2

Food

6.4

Boarding

7.5

Crew

7.9

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.1
Good
11,468 reviews
American Airlines
7.1
Good
11,468 reviews

Entertainment

6.9

Comfort

7.2

Food

6.4

Boarding

7.5

Crew

7.9

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana to Key West?

    There are many flights that can get you from Santa Ana to Key West in 17h 37m. Fly via Spirit Airlines or United Airlines to get the fastest option. Santa Ana and Key West are separated by a distance of 2254 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Santa Ana to Key West round-trip?

    Currently priced at $353, American Airlines will fly you from Santa Ana to Key West and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. This flight start at 43% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santa Ana to Key West that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Key West.

  • Can I find deals for business class flights from Santa Ana to Key West?

    Yes. Cheapflights offers flight deals from Santa Ana to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana to Key West?

    Currently, January is the cheapest month in which you can book a flight from Santa Ana to Key West (average of $250). Flying from Santa Ana to Key West in June is currently the most expensive (average of $483). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Santa Ana to Key West

Discover the top airline that operate flights from Santa Ana to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$353Average$559FlexibilityNo cancel feeOn-time71%

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