Key West

$167+ Cheap flights from Santa Ana, CA to Key West (SNA - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — EYW
Feb 28 — Mar 71
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Cheap flight deals from Santa Ana to Key West

Cheapest flights from Santa Ana to Key West
Explore the most affordable flight options available from Santa Ana to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:45 am
SNA
-
EYW
2 stops12h 37m
American Airlines
Tue 3/33:20 pm
EYW
-
SNA
1 stop8h 58m
American Airlines
Deal found 1/27$422
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:01 pm
SNA
-
EYW
2 stops15h 10m
American Airlines
Fri 3/202:06 pm
EYW
-
SNA
1 stop10h 11m
American Airlines
Deal found 1/28$481
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:40 pm
SNA
-
EYW
2 stops18h 27m
United Airlines
Wed 3/46:35 pm
EYW
-
SNA
2 stops18h 13m
United Airlines
Deal found 1/28$566
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:45 am
SNA
-
EYW
1 stop7h 17m
American Airlines
Tue 5/192:29 pm
EYW
-
SNA
1 stop8h 43m
American Airlines
Deal found 1/27$599

Find flight deals from Santa Ana to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$422
(American Airlines)

One-way from

$167
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$421
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Key West flight deals.
Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Key West flights.
From Santa Ana J. Wayne/Orange Cnty to Key West
One-way flight from Santa Ana J. Wayne/Orange Cnty to Key West
Highest demand for flights based on searches. 5% potential increase in price ($36 potential increase over avg. RT price).
Cheapest flight prices on average. 6% potential price decrease ($37 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santa Ana to Key West that are best for you.

Fly from

Santa Ana

Fly to

Key West

Route

Depart

Return

Price

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 2/24

6:45 am-10:22 pm

2 stops12h 37m

Key West

Tue 3/3

7:45 pm-8:50 am

2 stops16h 05m

$424

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

5:01 pm-11:11 am

2 stops15h 10m

Key West

Fri 3/20

2:06 pm-9:17 pm

1 stop10h 11m

$481

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

6:40 pm-4:07 pm

2 stops18h 27m

Key West

Wed 3/4

6:35 pm-9:48 am

2 stops18h 13m

$566

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Fri 5/15

6:45 am-5:02 pm

1 stop7h 17m

Key West

Tue 5/19

2:29 pm-8:12 pm

1 stop8h 43m

$599

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

8:58 am-11:03 am

3 stops47h 05m

$167

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

1:20 pm-1:30 pm

2 stops21h 10m

$189

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sun 2/15

11:22 am-12:21 pm

3 stops45h 59m

$279

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 3/7

6:34 pm-3:36 pm

2 stops18h 02m

$323

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 3/7

3:23 pm-5:19 pm

1 stop22h 56m

$327

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

10:51 am-10:09 pm

1 stop8h 18m

$386

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 13 results
1
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  • Most accurate provider: When it comes to deals on Santa Ana, California-Key West flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Santa Ana, California-Key West flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Santa Ana, California-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana, California-Key West flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Key West

What is the cheapest month to book a flight from Santa Ana, California to Key West?

Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Key West (average of $250). Flying from Santa Ana, California to Key West in June is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with American Airlines from Santa Ana to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Santa Ana, California to Key West?

    A quick flight from Santa Ana, California to Key West can take about 12h 37m. American Airlines provides one of the quickest options available for as low as $424. The distance from Santa Ana, California to Key West is about 2254 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Santa Ana, California to Key West round-trip?

    Cheapflights users have booked flights from Santa Ana, California to Key West round-trip from $348. This flight start at 41% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santa Ana to Key West that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Key West.

  • Can I find deals for business class flights from Santa Ana to Key West?

    Yes. Cheapflights offers flight deals from Santa Ana to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Key West?

    Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Key West (average of $250). Flying from Santa Ana, California to Key West in June is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Santa Ana to Key West

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Santa Ana to Key West

Discover the top airline that operate flights from Santa Ana to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$348Average$553FlexibilityNo cancel feeOn-time71%

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