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Key West

$129+ Cheap flights from San Diego to Key West (SAN - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — EYW
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from San Diego to Key West

Cheapest flights from San Diego to Key West
Explore the most affordable flight options available from San Diego to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:15 amSAN - EYW
1 stop8h 00mDelta
Mon 12/226:20 pmEYW - SAN
1 stop8h 08mDelta
Deal found 12/11$445
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:15 amSAN - EYW
1 stop7h 15mAmerican Airlines
Mon 12/2211:47 amEYW - SAN
2 stops9h 50mAmerican Airlines
Deal found 12/11$450
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:06 pmSAN - EYW
2 stops17h 11mMultiple Airlines
Mon 12/2911:11 amEYW - SAN
1 stop28h 25mMultiple Airlines
Deal found 12/10$611
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:46 amSAN - EYW
1 stop8h 06mAmerican Airlines
Sun 12/147:00 amEYW - SAN
2 stops10h 32mAmerican Airlines
Deal found 12/10$667
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:34 pmSAN - EYW
1 stop12h 12mUnited Airlines
Sun 12/144:05 pmEYW - SAN
1 stop9h 25mUnited Airlines
Deal found 12/10$669
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:30 pmSAN - EYW
2 stops12h 36mAmerican Airlines
Sat 12/278:00 amEYW - SAN
2 stops10h 24mAmerican Airlines
Deal found 12/11$776

Find flight deals from San Diego to Key West

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$261
(Delta)

One-way from

$129
(American Airlines)

Popular in

November

Cheapest in

September

Average price

$578
Provider with most accurate pricing for San Diego-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Key West flights.
Search Deals
From San Diego to Key West
Search Deals
One-way flight from San Diego to Key West
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from San Diego to Key West that are best for you.

Fly from

San Diego

Fly to

Key West

Route

Depart

Return

Price

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Thu 1/1

8:00 am-8:58 pm

1 stop9h 58m

Key West

Thu 1/8

2:45 pm-10:45 pm

1 stop11h 00m

$261

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Fri 1/23

1:27 pm-11:56 pm

1 stop7h 29m

Key West

Tue 1/27

2:58 pm-8:41 pm

1 stop8h 43m

$261

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Mon 1/12

10:40 pm-1:03 pm

1 stop11h 23m

Key West

Fri 1/16

4:15 pm-10:33 pm

1 stop9h 18m

$302

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Wed 1/28

1:27 pm-11:56 pm

1 stop7h 29m

Key West

Mon 2/2

4:37 pm-11:09 pm

1 stop9h 32m

$318

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Thu 1/29

9:21 am-11:56 pm

2 stops11h 35m

Key West

Mon 2/2

4:37 pm-11:09 pm

1 stop9h 32m

$384

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Wed 5/6

6:28 am-6:21 pm

2 stops8h 53m

Key West

Tue 5/12

3:06 pm-8:12 pm

1 stop8h 06m

$390

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Thu 1/1

8:00 am-8:58 pm

1 stop9h 58m

Key West

Sat 1/10

12:24 pm-7:39 pm

1 stop10h 15m

$402

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Sat 1/24

10:25 pm-10:57 am

1 stop9h 32m

$129

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Mon 3/9

1:01 pm-11:56 pm

1 stop7h 55m

$133

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Sat 1/24

10:34 am-12:26 pm

3 stops46h 52m

$147

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 15 results
1
2

Compare providers for flights from San Diego to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Key West in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Diego-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Diego-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Diego-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Diego-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Key West

What is the cheapest month to book a flight from San Diego to Key West?

Currently, April is the cheapest month in which you can book a flight from San Diego to Key West (average of $160). Flying from San Diego to Key West in July is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Delta and American Airlines from San Diego to Key West. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Diego to Key West?

    There are many flights that can get you from San Diego to Key West in 7h 29m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance between San Diego and Key West is about 2209 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from San Diego to Key West round-trip?

    Currently priced at $269, Delta will fly you from San Diego to Key West and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $314. You may be able to fly from San Diego to Key West for 47% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Diego to Key West that include hotel bookings?

    Yes. In addition to deals on San Diego to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Key West.

  • Can I find deals for business class flights from San Diego to Key West?

    Yes. Cheapflights offers flight deals from San Diego to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Key West?

    Currently, April is the cheapest month in which you can book a flight from San Diego to Key West (average of $160). Flying from San Diego to Key West in July is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from San Diego to Key West

Discover the top 2 airlines that operate flights from San Diego to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$278Average$458FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$314Average$546FlexibilityNo cancel feeOn-time71%

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