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Key Largo

$129+ Cheap flights from San Francisco (SFO) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — MIA
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Key Largo are usually found in January or August, booked 21 days in advance, depart on a Monday or Wednesday and return on a Thursday

Cheap flight deals from San Francisco to Key Largo

Keep the following information in mind while searching for San Francisco to Key Largo flight deals. Data was last updated septiembre 17, 2025.

Round-trip from

$239
(Kiwi.com)

One-way from

$129
(Delta)

Popular in

December

Cheapest in

January

Average price

$356
From San Francisco to Key Largo
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One-way flight from San Francisco to Key Largo
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Highest demand for flights based on searches. 5% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Francisco to Key Largo

Cheapest flights from San Francisco to Key Largo
Explore the most affordable flight options available from San Francisco to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/318:09 pmSFO - MIA
1 stop7h 10mFrontier
sáb. 11/86:00 amMIA - SFO
1 stop15h 45mFrontier
Deal found 9/17$239
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/155:00 amSFO - MIA
1 stop7h 47mUnited Airlines
sáb. 10/186:35 pmMIA - SFO
Nonstop6h 15mUnited Airlines
Deal found 9/15$241
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/277:00 amSFO - MIA
Nonstop5h 36mUnited Airlines
sáb. 12/68:30 amMIA - SFO
Nonstop6h 33mUnited Airlines
Deal found 9/15$242
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/266:34 amSFO - MIA
2 stops25h 00mFrontier
vie. 10/317:07 pmMIA - SFO
2 stops30h 20mFrontier
Deal found 9/15$243
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/86:34 amSFO - MIA
2 stops24h 37mFrontier
sáb. 11/156:35 pmMIA - SFO
2 stops20h 40mFrontier
Deal found 9/15$244
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/128:53 amSFO - MIA
Nonstop5h 40mUnited Airlines
sáb. 10/186:35 pmMIA - SFO
Nonstop6h 15mUnited Airlines
Deal found 9/15$245
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/128:21 pmSFO - MIA
2 stops21h 05mFrontier
jue. 10/166:00 amMIA - SFO
1 stop21h 14mFrontier
Deal found 9/15$246
This Orbitz deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/311:00 pmSFO - MIA
1 stop14h 30mMultiple Airlines
mar. 10/76:43 pmMIA - SFO
1 stop17h 33mMultiple Airlines
Deal found 9/16$247
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/257:07 pmSFO - MIA
1 stop26h 37mFrontier
mié. 10/16:57 pmMIA - SFO
1 stop29h 24mFrontier
Deal found 9/15$249
This Alaska Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/259:47 pmSFO - MIA
1 stop16h 59mAlaska Airlines
mar. 11/46:46 pmMIA - SFO
1 stop18h 58mAlaska Airlines
Deal found 9/17$250

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from San Francisco to Key Largo that are best for you.

Fly from

San Francisco

Fly to

Key Largo

Route

Depart

Return

Price

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

mié. 12/3

7:20 am-5:53 pm

1 stop7h 33m

Miami

sáb. 12/6

11:55 am-5:46 pm

1 stop8h 51m

$246

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

mar. 12/9

11:36 am-4:00 pm

1 stop25h 24m

Miami

mié. 12/17

5:00 pm-9:17 am

1 stop19h 17m

$250

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

sáb. 10/18

5:05 am-3:47 pm

1 stop7h 42m

Miami

sáb. 10/25

4:17 pm-10:31 pm

1 stop9h 14m

$251

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

sáb. 11/8

1:45 pm-12:29 am

1 stop7h 44m

Miami

mar. 11/11

7:00 am-12:30 pm

1 stop8h 30m

$257

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

mar. 11/18

6:00 am-5:18 pm

1 stop8h 18m

Miami

mié. 12/3

7:40 am-2:37 pm

1 stop9h 57m

$257

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

lun. 11/3

12:35 am-1:28 pm

1 stop9h 53m

Miami

sáb. 11/8

7:36 am-2:33 pm

1 stop9h 57m

$257

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

sáb. 10/25

6:10 am-5:10 pm

1 stop8h 00m

Miami

vie. 10/31

8:30 am-2:13 pm

1 stop8h 43m

$268

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

jue. 10/9

5:50 am-5:35 pm

1 stop8h 45m

Miami

mar. 10/14

7:36 am-2:33 pm

1 stop9h 57m

$268

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

sáb. 11/15

12:45 am-1:32 pm

1 stop9h 47m

Miami

mar. 12/9

7:40 am-2:37 pm

1 stop9h 57m

$268

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

dom. 11/2

5:10 am-4:10 pm

1 stop8h 00m

Miami

mié. 11/12

6:23 pm-11:58 pm

1 stop8h 35m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 21 results
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2
3

Best time to book a flight from San Francisco to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Key Largo

How far ahead should I book a flight from San Francisco to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Key Largo. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from San Francisco to Key Largo, you should look to book at least 21 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Key Largo?

Currently, September is the cheapest month in which you can book a flight from San Francisco to Key Largo (average of $232). Flying from San Francisco to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to KE9?

Find hourly flight availability from San Francisco to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from San Francisco to Key Largo as you normally would.

What is the cheapest day to fly from San Francisco to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Key Largo flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Key Largo

Explore weekly flight availability from San Francisco to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated septiembre 17, 2025.

The most flights from SFO to KE9 are scheduled on a Tuesday (17 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (11 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated septiembre 17, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from San Francisco to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
JetBlue
7.2
Good
2,914 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Frontier
5.8
Fair
3,173 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Key Largo?

    If you book a flight to Key Largo from San Francisco, you will be flying from San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco. There are 15 flights from San Francisco to Key Largo per day from 8 different airlines.

  • How popular is this San Francisco to Key Largo flight route?

    Within the past month, 38 users have taken a look at flights from San Francisco to Key Largo.

  • How long is the flight from San Francisco to Key Largo?

    Airlines like United Airlines, Alaska Airlines, and Delta fly from San Francisco to Key Largo in about 7h 33m. The time it takes to get you to your destination can typically vary by up to 17h 51m. Airlines will cover a distance of 2579 mi. This flight may include one or multiple stops.

  • What are the most reliable airlines from San Francisco to Key Largo?

    Before booking your flight to Key Largo from San Francisco, check out the most reliable airlines to get you to your destination on time: Fiji Airways (90%), British Airways (84%), Royal Air Maroc( 84%).

  • What are the cheapest flights from San Francisco to Key Largo?

    While on average a flight from San Francisco to Key Largo is generally $1,151, our data shows the cheapest flight currently is $115. When looking at the most popular route, (San Francisco - Miami), you can expect to pay $215 for that flight.

  • Can I find deals for flights from San Francisco to Key Largo that include hotel bookings?

    Yes. In addition to deals on San Francisco to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Key Largo.

  • Can I find deals for business class flights from San Francisco to Key Largo?

    Yes. Cheapflights offers flight deals from San Francisco to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from San Francisco to Key Largo (average of $232). Flying from San Francisco to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 8 airlines flying from San Francisco to Key Largo

Discover the top 8 airlines that operate flights from San Francisco to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$105Average$300FlexibilityNo cancel feeOn-time65%
DeltaCheapest$129Average$371FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$130Average$353FlexibilityNo cancel feeOn-time62%
FrontierCheapest$132Average$222FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$168Average$389FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$181Average$465FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$217Average$490FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$238Average$422FlexibilityNo cancel feeOn-time63%

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