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Key Largo

$124+ Cheap flights from San Francisco (SFO) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — MIA
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Key Largo are usually found in January or August, booked 21 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from San Francisco to Key Largo

Keep the following information in mind while searching for San Francisco to Key Largo flight deals. Data was last updated August 14, 2025.

Round-trip from

$246
(Kiwi.com)

One-way from

$124
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$331
From San Francisco to Key Largo
Search Deals
One-way flight from San Francisco to Key Largo
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Highest demand for flights based on searches. 5% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from San Francisco to Key Largo

Cheapest flights from San Francisco to Key Largo
Explore the most affordable flight options available from San Francisco to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/811:57 pmSFO - MIA
1 stop10h 03mMultiple Airlines
Thu 9/117:23 pmMIA - SFO
1 stop16h 13mMultiple Airlines
Deal found 8/13$246
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1611:58 pmSFO - MIA
Nonstop5h 35mAmerican Airlines
Tue 9/237:43 pmMIA - SFO
Nonstop6h 11mAmerican Airlines
Deal found 8/14$247
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/37:00 amSFO - MIA
2 stops10h 40mSouthwest
Thu 9/44:10 pmMIA - SFO
1 stop10h 00mSouthwest
Deal found 8/12$248
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/318:00 amSFO - MIA
Nonstop5h 46mAmerican Airlines
Sat 9/67:45 amMIA - SFO
1 stop11h 18mAmerican Airlines
Deal found 8/12$249
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/311:59 pmSFO - MIA
1 stop8h 43mUnited Airlines
Sat 9/68:00 amMIA - SFO
1 stop8h 22mUnited Airlines
Deal found 8/12$251
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/38:00 amSFO - MIA
2 stops37h 44mFrontier
Sun 9/73:46 pmMIA - SFO
1 stop10h 16mFrontier
Deal found 8/14$252
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/411:10 amSFO - MIA
Nonstop5h 51mAmerican Airlines
Tue 9/97:43 pmMIA - SFO
Nonstop6h 11mAmerican Airlines
Deal found 8/14$253
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2010:23 pmSFO - MIA
1 stop13h 09mFrontier
Mon 10/276:00 amMIA - SFO
1 stop11h 22mFrontier
Deal found 8/12$254
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/411:10 amSFO - MIA
Nonstop5h 51mAmerican Airlines
Wed 9/107:43 pmMIA - SFO
Nonstop6h 11mAmerican Airlines
Deal found 8/14$255
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/318:00 amSFO - MIA
Nonstop5h 46mAmerican Airlines
Tue 9/97:43 pmMIA - SFO
Nonstop6h 11mAmerican Airlines
Deal found 8/13$256
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/315:55 amSFO - MIA
1 stop8h 36mDelta
Wed 9/37:50 amMIA - SFO
1 stop10h 00mDelta
Deal found 8/13$257

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from San Francisco to Key Largo that are best for you.

Fly from

San Francisco

Fly to

Key Largo

Route

Depart

Return

Price

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Wed 10/22

8:00 am-4:26 pm

Nonstop5h 26m

Miami

Wed 10/29

8:15 am-11:27 am

Nonstop6h 12m

$247

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Tue 9/16

11:58 pm-8:33 am

Nonstop5h 35m

Miami

Tue 9/23

7:43 pm-10:54 pm

Nonstop6h 11m

$247

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Wed 9/24

9:19 pm-5:45 pm

1 stop17h 26m

Miami

Wed 10/1

6:52 pm-9:12 am

1 stop17h 20m

$250

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Mon 9/15

12:45 am-1:34 pm

1 stop9h 49m

Miami

Tue 9/23

6:00 am-10:34 am

1 stop7h 34m

$250

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Fri 9/12

12:43 am-11:02 am

1 stop7h 19m

Miami

Sat 9/20

8:00 am-1:22 pm

1 stop8h 22m

$251

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Sat 11/8

5:15 am-3:44 pm

1 stop7h 29m

Miami

Sat 11/15

6:30 am-12:10 pm

1 stop8h 40m

$251

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Tue 10/21

12:43 am-11:00 am

1 stop7h 17m

Miami

Wed 10/29

6:30 am-12:10 pm

1 stop8h 40m

$251

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Tue 10/14

12:43 am-11:00 am

1 stop7h 17m

Miami

Tue 10/21

11:13 am-7:00 pm

1 stop10h 47m

$251

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Tue 9/23

12:43 am-11:02 am

1 stop7h 19m

Miami

Sat 9/27

8:45 am-2:40 pm

1 stop8h 55m

$251

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Tue 11/11

5:50 am-4:00 pm

1 stop7h 10m

Miami

Fri 11/14

3:10 pm-9:50 pm

1 stop9h 40m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 20 results
1
2

Best time to book a flight from San Francisco to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Key Largo

How far ahead should I book a flight from San Francisco to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Key Largo. Price data was last updated on August 8, 2025.

To ensure you get the cheapest price possible for a flight from San Francisco to Key Largo, you should look to book at least 21 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Key Largo?

Currently, September is the cheapest month in which you can book a flight from San Francisco to Key Largo (average of $232). Flying from San Francisco to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to KE9?

Find hourly flight availability from San Francisco to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from San Francisco to Key Largo as you normally would.

What is the cheapest day to fly from San Francisco to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Key Largo flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Key Largo

Explore weekly flight availability from San Francisco to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 14, 2025.

The most flights from SFO to KE9 are scheduled on a Thursday (26 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (17 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated August 14, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from San Francisco to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
JetBlue
7.2
Good
2,913 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Frontier
5.8
Fair
3,217 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Key Largo?

    If you book a flight to Key Largo from San Francisco, you will be flying from San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco. There are 21 flights from San Francisco to Key Largo per day from 8 different airlines.

  • How popular is this San Francisco to Key Largo flight route?

    Within the past month, 39 users have taken a look at flights from San Francisco to Key Largo.

  • What are the most reliable airlines from San Francisco to Key Largo?

    Before booking your flight to Key Largo from San Francisco, check out the most reliable airlines to get you to your destination on time: Royal Air Maroc (100%), Fiji Airways (94%), Qatar Airways( 92%).

  • What are the cheapest flights from San Francisco to Key Largo?

    While on average a flight from San Francisco to Key Largo is generally $945, our data shows the cheapest flight currently is $131. When looking at the most popular route, (San Francisco - Miami), you can expect to pay $215 for that flight.

  • Can I find deals for flights from San Francisco to Key Largo that include hotel bookings?

    Yes. In addition to deals on San Francisco to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Key Largo.

  • Can I find deals for business class flights from San Francisco to Key Largo?

    Yes. Cheapflights offers flight deals from San Francisco to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from San Francisco to Key Largo (average of $232). Flying from San Francisco to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 8 airlines flying from San Francisco to Key Largo

Discover the top 8 airlines that operate flights from San Francisco to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$105Average$297FlexibilityNo cancel feeOn-time65%
DeltaCheapest$128Average$370FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$130Average$253FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$146Average$349FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$161Average$376FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$181Average$463FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$217Average$489FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$270Average$430FlexibilityNo cancel feeOn-time63%

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