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Key Largo

$130+ Cheap flights from San Francisco (SFO) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — MIA
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Key Largo are usually found in January or August, booked 84 days in advance, depart on a Monday or Wednesday and return on a Friday

Cheap flight deals from San Francisco to Key Largo

Cheapest flights from San Francisco to Key Largo
Explore the most affordable flight options available from San Francisco to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.

This Frontier deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmSFO - MIA
1 stop8h 38mFrontier
Thu 1/85:20 amMIA - SFO
1 stop10h 58mFrontier
Deal found 12/21$254
This Frontier deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmSFO - MIA
1 stop8h 38mFrontier
Sun 1/115:20 amMIA - SFO
1 stop10h 58mFrontier
Deal found 12/19$267
This Frontier deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmSFO - MIA
1 stop8h 38mFrontier
Fri 1/95:20 amMIA - SFO
1 stop10h 58mFrontier
Deal found 12/21$268
This Frontier deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmSFO - MIA
1 stop8h 38mFrontier
Tue 1/67:05 amMIA - SFO
1 stop11h 48mFrontier
Deal found 12/21$278
This Kiwi.com deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmSFO - MIA
1 stop8h 38mMultiple Airlines
Mon 1/510:19 pmMIA - SFO
2 stops27h 40mMultiple Airlines
Deal found 12/19$296
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmSFO - MIA
1 stop8h 38mFrontier
Wed 1/77:09 pmMIA - SFO
2 stops39h 54mFrontier
Deal found 12/21$299
This Frontier deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:20 pmSFO - MIA
1 stop8h 38mFrontier
Thu 1/85:20 amMIA - SFO
1 stop10h 58mFrontier
Deal found 12/21$303
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmSFO - MIA
1 stop8h 38mMultiple Airlines
Wed 1/72:19 pmMIA - SFO
2 stops20h 44mMultiple Airlines
Deal found 12/21$308
This Frontier deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:20 pmSFO - MIA
1 stop8h 38mFrontier
Wed 1/145:15 amMIA - SFO
1 stop11h 09mFrontier
Deal found 12/19$312
This United Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:05 pmSFO - MIA
1 stop8h 25mUnited Airlines
Tue 1/136:15 pmMIA - SFO
Nonstop6h 35mUnited Airlines
Deal found 12/19$313
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 pmSFO - MIA
1 stop8h 38mMultiple Airlines
Fri 1/98:51 pmMIA - SFO
2 stops19h 40mMultiple Airlines
Deal found 12/21$315

Find flight deals from San Francisco to Key Largo

Keep the following information in mind while searching for San Francisco to Key Largo flight deals. Data was last updated December 21, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$253
(Kiwi.com)

One-way from

$130
(United Airlines)

Popular in

December

Cheapest in

January

Average price

$503
Provider with most accurate pricing for San Francisco-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Miami flights.
Search Deals
From San Francisco to Key Largo
Search Deals
One-way flight from San Francisco to Key Largo
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from San Francisco to Key Largo that are best for you.

Fly from

San Francisco

Fly to

Key Largo

Route

Depart

Return

Price

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Wed 1/28

2:35 pm-5:28 am

2 stops11h 53m

Miami

Tue 2/3

8:05 am-5:49 pm

2 stops12h 44m

$256

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Fri 3/6

11:00 pm-7:27 am

Nonstop5h 27m

Miami

Sat 3/14

7:23 am-10:59 am

Nonstop6h 36m

$259

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Mon 1/12

11:18 pm-7:51 am

Nonstop5h 33m

Miami

Fri 1/16

6:05 am-9:43 am

Nonstop6h 38m

$259

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Mon 3/2

11:00 pm-7:27 am

Nonstop5h 27m

Miami

Thu 3/12

4:10 pm-12:16 am

1 stop11h 06m

$265

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Mon 2/16

10:45 pm-10:21 am

1 stop8h 36m

Miami

Fri 2/20

7:50 am-3:03 pm

1 stop10h 13m

$268

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Tue 1/13

11:18 pm-7:51 am

Nonstop5h 33m

Miami

Tue 1/20

9:05 am-2:56 pm

1 stop8h 51m

$284

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Thu 1/15

5:00 am-6:25 pm

1 stop10h 25m

Miami

Sat 1/17

6:05 am-9:43 am

Nonstop6h 38m

$287

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Tue 3/3

8:32 am-4:56 pm

Nonstop5h 24m

Miami

Mon 3/9

6:02 pm-9:50 pm

Nonstop6h 48m

$287

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Fri 2/6

9:30 pm-9:26 am

1 stop8h 56m

Miami

Sat 2/14

7:50 am-3:03 pm

1 stop10h 13m

$288

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Fri 6/19

7:01 pm-5:50 am

1 stop7h 49m

Miami

Fri 6/26

7:00 am-12:18 pm

1 stop8h 18m

$301

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from San Francisco to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Key Largo

How far ahead should I book a flight from San Francisco to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Key Largo. Price data was last updated on December 19, 2025.

To ensure you get the cheapest price possible for a flight from San Francisco to Key Largo, you should look to book at least 84 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Key Largo?

Currently, May is the cheapest month in which you can book a flight from San Francisco to Key Largo (average of $98). Flying from San Francisco to Key Largo in April is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to KE9?

Find hourly flight availability from San Francisco to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 21, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 17% on flights from San Francisco to Key Largo by exploring options for tickets in the morning.

What is the cheapest day to fly from San Francisco to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Key Largo flight should consider departing on Friday mornings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Key Largo

Explore weekly flight availability from San Francisco to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 21, 2025.

The most flights from SFO to KE9 are scheduled on a Friday (26 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (9 on average).

How much does it cost to fly round-trip from San Francisco to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated December 21, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from San Francisco to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,019 reviews
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
9,099 reviews
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
JetBlue
7.2
Good
2,896 reviews
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Frontier
5.8
Fair
3,082 reviews
Delta
7.9
Good
8,019 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Key Largo?

    If you book a flight to Key Largo from San Francisco, you will be flying from San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco. There are 21 flights from San Francisco to Key Largo per day from 8 different airlines.

  • How popular is this San Francisco to Key Largo flight route?

    Within the past month, 27 users have taken a look at flights from San Francisco to Key Largo.

  • How long is the flight from San Francisco to Key Largo?

    Airlines like United Airlines and Delta fly from San Francisco to Key Largo in about 5h 36m. The time it takes to get you to your destination can typically vary by up to 3h 39m. Airlines will cover a distance of 2579 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Francisco to Key Largo one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $72. However, be on the lookout for offers from Alaska Airlines and Southwest, as they are both options that can get you from San Francisco to Key Largo for a low price.

  • What are the most reliable airlines from San Francisco to Key Largo?

    Before booking your flight to Key Largo from San Francisco, check out the most reliable airlines to get you to your destination on time: Finnair (100%), Air New Zealand (95%), United Airlines( 93%).

  • What are the cheapest flights from San Francisco to Key Largo?

    While on average a flight from San Francisco to Key Largo is generally $1,237, our data shows the cheapest flight currently is $129. When looking at the most popular route, (San Francisco - Miami), you can expect to pay $176 for that flight.

  • Can I find deals for flights from San Francisco to Key Largo that include hotel bookings?

    Yes. In addition to deals on San Francisco to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Key Largo.

  • Can I find deals for business class flights from San Francisco to Key Largo?

    Yes. Cheapflights offers flight deals from San Francisco to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Key Largo?

    Currently, May is the cheapest month in which you can book a flight from San Francisco to Key Largo (average of $98). Flying from San Francisco to Key Largo in April is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 8 airlines flying from San Francisco to Key Largo

Discover the top 8 airlines that operate flights from San Francisco to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$117Average$232FlexibilityNo cancel feeOn-time62%
DeltaCheapest$133Average$377FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$180Average$362FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$182Average$221FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$182Average$394FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$187Average$412FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$198Average$456FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$217Average$354FlexibilityNo cancel feeOn-time75%

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