Key Largo

$109+ Cheap flights from San Francisco (SFO) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — MIA
Mar 9 — Mar 161
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Francisco to Key Largo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from San Francisco to Key Largo are usually found in August or September, booked 21 days in advance, depart on a Monday or Wednesday and return on a Friday

Cheap flight deals from San Francisco to Key Largo

Cheapest flights from San Francisco to Key Largo
Explore the most affordable flight options available from San Francisco to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1010:40 pm
SFO
-
MIA
1 stop8h 54m
Multiple Airlines
Thu 3/1911:34 am
MIA
-
SFO
2 stops23h 24m
Multiple Airlines
Deal found 2/6$249
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:40 pm
SFO
-
MIA
1 stop18h 27m
Multiple Airlines
Sat 3/145:05 am
MIA
-
SFO
1 stop17h 09m
Multiple Airlines
Deal found 2/6$250
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2111:00 pm
SFO
-
MIA
1 stop8h 28m
Frontier
Sat 2/286:00 am
MIA
-
SFO
2 stops19h 21m
Frontier
Deal found 2/5$251
This CheapOair deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:09 pm
SFO
-
MIA
1 stop8h 19m
Frontier
Sat 2/286:25 am
MIA
-
SFO
1 stop28h 38m
Frontier
Deal found 2/4$252
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:55 am
SFO
-
MIA
1 stop19h 19m
Frontier
Thu 2/129:10 pm
MIA
-
SFO
1 stop15h 23m
Frontier
Deal found 2/3$253
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:46 pm
SFO
-
MIA
1 stop8h 42m
Multiple Airlines
Mon 3/27:05 am
MIA
-
SFO
1 stop17h 34m
Multiple Airlines
Deal found 2/4$254
This Frontier deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/111:09 pm
SFO
-
MIA
1 stop8h 19m
Frontier
Mon 4/275:05 am
MIA
-
SFO
1 stop14h 49m
Frontier
Deal found 2/5$255
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:25 am
SFO
-
MIA
2 stops13h 17m
Frontier
Fri 5/18:42 am
MIA
-
SFO
1 stop11h 10m
Frontier
Deal found 2/5$256
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:48 am
SFO
-
MIA
2 stops12h 54m
Frontier
Thu 3/1212:26 pm
MIA
-
SFO
1 stop9h 48m
Frontier
Deal found 2/3$257
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:38 pm
SFO
-
MIA
1 stop16h 15m
Frontier
Mon 3/98:55 am
MIA
-
SFO
2 stops18h 33m
Frontier
Deal found 2/3$258
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:50 pm
SFO
-
MIA
Nonstop5h 35m
American Airlines
Tue 8/117:51 pm
MIA
-
SFO
Nonstop6h 07m
American Airlines
Deal found 2/5$259
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:03 pm
SFO
-
MIA
1 stop9h 19m
Frontier
Wed 4/158:42 am
MIA
-
SFO
1 stop8h 44m
Frontier
Deal found 2/3$260

Find flight deals from San Francisco to Key Largo

Keep the following information in mind while searching for San Francisco to Key Largo flight deals. Data was last updated February 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$249
(Kiwi.com)

One-way from

$109
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$398
Provider with most accurate pricing for San Francisco-Miami flight deals.
Provider most trusted by Cheapflights users for San Francisco-Miami flights.
From San Francisco to Key Largo
One-way flight from San Francisco to Key Largo
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from San Francisco to Key Largo that are best for you.

Fly from

San Francisco

Fly to

Key Largo

Route

Depart

Return

Price

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Fri 2/20

6:55 pm-6:35 am

1 stop8h 40m

Miami

Thu 2/26

7:50 am-3:03 pm

1 stop10h 13m

$257

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Fri 3/6

11:00 pm-7:27 am

Nonstop5h 27m

Miami

Wed 3/11

7:00 am-10:30 am

Nonstop6h 30m

$263

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Fri 2/20

12:43 am-10:55 am

1 stop7h 12m

Miami

Thu 2/26

8:35 am-12:11 pm

Nonstop6h 36m

$267

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Thu 2/26

11:59 pm-10:55 am

1 stop7h 56m

Miami

Sat 2/28

8:35 am-12:11 pm

Nonstop6h 36m

$273

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Sat 4/11

11:05 pm-7:54 am

Nonstop5h 49m

Miami

Fri 4/17

7:15 am-10:46 am

Nonstop6h 31m

$283

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Sun 4/12

11:05 pm-7:54 am

Nonstop5h 49m

Miami

Sat 4/18

7:15 am-10:46 am

Nonstop6h 31m

$294

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Wed 3/4

11:00 pm-7:27 am

Nonstop5h 27m

Miami

Wed 3/11

7:00 am-10:30 am

Nonstop6h 30m

$299

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Thu 3/12

11:00 pm-7:27 am

Nonstop5h 27m

Miami

Mon 3/16

6:02 pm-9:50 pm

Nonstop6h 48m

$318

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Mon 2/23

11:00 pm-7:27 am

Nonstop5h 27m

Miami

Thu 3/19

7:23 am-10:59 am

Nonstop6h 36m

$318

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Wed 4/22

8:29 am-5:11 pm

Nonstop5h 42m

Miami

Mon 4/27

4:13 pm-12:19 am

1 stop11h 06m

$318

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/6

Showing 1-10 of 23 results
1
2
3

Best time to book a flight from San Francisco to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Key Largo

How far ahead should I book a flight from San Francisco to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Key Largo. Price data was last updated on January 30, 2026.

To ensure you get the cheapest price possible for a flight from San Francisco to Key Largo, you should look to book at least 21 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Key Largo?

Currently, May is the cheapest month in which you can book a flight from San Francisco to Key Largo (average of $98). Flying from San Francisco to Key Largo in April is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to KE9?

Find hourly flight availability from San Francisco to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 7, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 17% on flights from San Francisco to Key Largo by exploring options for tickets in the morning.

What is the cheapest day to fly from San Francisco to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Key Largo. Price data was last updated on January 31, 2026.

Travelers seeking maximum savings on their San Francisco to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Key Largo

Explore weekly flight availability from San Francisco to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 7, 2026.

The most flights from SFO to KE9 are scheduled on a Friday (27 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (24 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated February 7, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from San Francisco to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to Key Largo?

    If you book a flight to Key Largo from San Francisco, you will be flying from San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco. There are 25 flights from San Francisco to Key Largo per day from 7 different airlines.

  • How popular is this San Francisco to Key Largo flight route?

  • How long is the flight from San Francisco to Key Largo?

    Airlines like Delta and United Airlines fly from San Francisco to Key Largo in about 5h 27m. The time it takes to get you to your destination can typically vary by up to 3h 13m. Airlines will cover a distance of 2579 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Francisco to Key Largo one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $74. However, be on the lookout for offers from Alaska Airlines and Southwest, as they are both options that can get you from San Francisco to Key Largo for a low price.

  • What are the most reliable airlines from San Francisco to Key Largo?

    Before booking your flight to Key Largo from San Francisco, check out the most reliable airlines to get you to your destination on time: ITA Airways (90%), United Airlines (89%), Iberia( 88%).

  • What are the cheapest flights from San Francisco to Key Largo?

    While on average a flight from San Francisco to Key Largo is generally $1,386, our data shows the cheapest flight currently is $117. When looking at the most popular route, (San Francisco - Miami), you can expect to pay $189 for that flight.

  • Can I find deals for flights from San Francisco to Key Largo that include hotel bookings?

    Yes. In addition to deals on San Francisco to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Key Largo.

  • Can I find deals for business class flights from San Francisco to Key Largo?

    Yes. Cheapflights offers flight deals from San Francisco to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Key Largo?

    Currently, May is the cheapest month in which you can book a flight from San Francisco to Key Largo (average of $98). Flying from San Francisco to Key Largo in April is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from San Francisco to Key Largo

Discover the top 7 airlines that operate flights from San Francisco to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$92Average$221FlexibilityNo cancel feeOn-time62%
Alaska AirlinesCheapest$118Average$251FlexibilityNo cancel feeOn-time75%
DeltaCheapest$128Average$366FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$148Average$354FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$179Average$461FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$182Average$391FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$187Average$412FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.