What are the cheapest airlines to fly from Columbus Airport to Key Largo one-way?

For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $44. Users have also found prices from $65 and $115 on Frontier and American Airlines, respectively.

Weekly flight availability from Columbus Airport to Key Largo

The most flights from CMH to KE9 are scheduled on a Monday (6 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (2 on average).

In terms of precipitation, rainfall in Key Largo ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Key Largo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Key Largo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

What are the cheapest flights from Columbus Airport to Key Largo?

The cheapest flight price from Columbus Airport to Key Largo is $138. On average you can expect to pay $703. The most popular route, (Columbus - Miami), can usually be booked for $159.

What are the most reliable airlines from Columbus Airport to Key Largo?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Columbus Airport to Key Largo on time: American Airlines (89%), Envoy Air (89%), GOL (87%).

What are the most popular airlines that fly from Columbus Airport to Key Largo?

Consider American Airlines, Southwest or Frontier when booking your flight. These represent the most popular airlines when flying from Columbus Airport to Key Largo.

Can I find deals for flights from Columbus to Key Largo that include hotel bookings?

Yes. In addition to deals on Columbus to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Columbus to Key Largo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Key Largo.

Can I find deals for business class flights from Columbus to Key Largo?

Yes. Cheapflights offers flight deals from Columbus to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Cheap Flights from Columbus Airport to Key Largo

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Cheapflights Tip: The best prices from Columbus to Key Largo are usually found in January or February, booked 79 days in advance, depart on a Saturday or Sunday and return on a Wednesday

Find flight deals from Columbus to Key Largo

Popular in	June
Cheapest in	January
Average price	$392

Highest demand for flights based on searches. 4% potential increase in price ($17 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in October 2026

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Everything you need to know about your flight from Columbus Airport to Key Largo

Prices

Airlines

What is the cheapest time of day to fly from CMH to KE9?

It’s optimal to fly from Columbus Airport to Key Largo in the evening. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Columbus Airport to Key Largo?

Travelers seeking maximum savings on their Columbus Airport to Key Largo flight should consider departing on Monday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get a feel of what it's like to fly with Southwest,Delta, andJetBlue from Columbus Airport to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,220 reviews

Reviews

1 / 20

6.0

Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Southwest

7.9

Good

4,220 reviews

Southwest

7.9

Good

4,220 reviews

Reviews

1 / 20

6.0

Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Delta

7.8

Good

8,636 reviews

Southwest

7.9

Good

4,220 reviews

Reviews

1 / 20

6.0

Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

JetBlue

7.1

Good

3,046 reviews

Southwest

7.9

Good

4,220 reviews

Reviews

1 / 20

6.0

Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

American Airlines

7.0

Good

12,138 reviews

Southwest

7.9

Good

4,220 reviews

Reviews

1 / 20

6.0

Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Frontier

5.6

Fair

2,551 reviews

Southwest

7.9

Good

4,220 reviews

Reviews

1 / 20

6.0

Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Related info for your journey

What are the cheapest airlines to fly from Columbus Airport to Key Largo one-way?
For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $44. Users have also found prices from $65 and $115 on Frontier and American Airlines, respectively.
What are the most reliable airlines from Columbus Airport to Key Largo?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Columbus Airport to Key Largo on time: American Airlines (89%), Envoy Air (89%), GOL (87%).
What are the cheapest flights from Columbus Airport to Key Largo?
The cheapest flight price from Columbus Airport to Key Largo is $138. On average you can expect to pay $703. The most popular route, (Columbus - Miami), can usually be booked for $159.
Can I find deals for flights from Columbus to Key Largo that include hotel bookings?
Yes. In addition to deals on Columbus to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Columbus to Key Largo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Key Largo.
Can I find deals for business class flights from Columbus to Key Largo?
Yes. Cheapflights offers flight deals from Columbus to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 8 airlines flying from Columbus to Key Largo

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$72	Average$267	FlexibilityNo cancel fee	On-time88%
Frontier	Cheapest$80	Average$219	FlexibilityNo cancel fee	On-time62%
Breeze Airways	Cheapest$124	Average$220	FlexibilityNo cancel fee	On-timeN/A
JetBlue	Cheapest$168	Average$342	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$196	Average$396	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$206	Average$407	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$216	Average$421	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$238	Average$422	FlexibilityNo cancel fee	On-time63%

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Cheap flights from Columbus (CMH) to Key Largo, FL

Find cheap flights from Columbus to Key Largo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Columbus to Key Largo

Popular in

Cheapest in

Average price

Cheapflights Insights

What is the cheapest time of day to fly from CMH to KE9?

It’s optimal to fly from Columbus Airport to Key Largo in the evening. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Columbus Airport to Key Largo?

Travelers seeking maximum savings on their Columbus Airport to Key Largo flight should consider departing on Monday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Columbus Airport to Key Largo

The most flights from CMH to KE9 are scheduled on a Monday (6 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Key Largo

Get a feel of what it's like to fly with Southwest,Delta, andJetBlue from Columbus Airport to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What are the cheapest airlines to fly from Columbus Airport to Key Largo one-way?

What are the most reliable airlines from Columbus Airport to Key Largo?

What are the cheapest flights from Columbus Airport to Key Largo?

Can I find deals for flights from Columbus to Key Largo that include hotel bookings?

How can I find direct flights from Columbus to Key Largo?

Can I find deals for business class flights from Columbus to Key Largo?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Columbus to Key Largo

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Complete your trip

Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Columbus to Key Largo by cabin class

Find flights from Columbus to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Columbus and Key Largo flights

Browse other Columbus and Key Largo flight options. Last updated on October 9, 2026.

Other flights from Columbus

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Columbus to Key Largo flights

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Top 8 airlines flying from Columbus to Key Largo

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