$122+ Cheap flights from Knoxville (TYS) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MIA
Jul 6 — Jul 131
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key Largo are usually found in February or August, booked 74 days in advance, depart on a Friday or Saturday and return on a Wednesday
Cheap flight deals from Knoxville to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to Key LargoExplore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 6, 2026.
Explore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:55 pm
TYS
- MIA
2 stops21h 21m
Multiple Airlines
Sun 9/69:38 pm
MIA
- TYS
1 stop16h 02m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$262
This Frontier deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:19 pm
TYS
- MIA
1 stop9h 32m
Frontier
Mon 7/276:00 am
MIA
- TYS
1 stop13h 24m
Frontier
Deal found 6/3![Frontier logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/263:38 pm
TYS
- MIA
1 stop28h 48m
Multiple Airlines
Fri 7/318:30 am
MIA
- TYS
2 stops13h 30m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:07 pm
TYS
- MIA
1 stop6h 14m
American Airlines
Wed 7/159:45 pm
MIA
- TYS
Nonstop2h 14m
American Airlines
Deal found 6/5![American Airlines logo]()
$275
This Frontier deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:32 pm
TYS
- MIA
1 stop9h 22m
Frontier
Wed 7/16:00 am
MIA
- TYS
1 stop13h 37m
Frontier
Deal found 6/1![Frontier logo]()
$284
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
TYS
- MIA
Nonstop2h 12m
American Airlines
Sat 8/294:47 pm
MIA
- TYS
Nonstop2h 23m
American Airlines
Deal found 6/5![American Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:44 pm
TYS
- MIA
1 stop28h 42m
Multiple Airlines
Sun 7/123:39 pm
MIA
- TYS
1 stop25h 03m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:10 am
TYS
- MIA
1 stop6h 15m
Southwest
Wed 7/1511:25 am
MIA
- TYS
2 stops9h 55m
Southwest
Deal found 6/5![Southwest logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:52 am
TYS
- MIA
1 stop9h 41m
Multiple Airlines
Sun 9/138:50 pm
MIA
- TYS
1 stop22h 44m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:10 am
TYS
- MIA
2 stops9h 00m
Southwest
Tue 8/1111:50 am
MIA
- TYS
1 stop8h 00m
Southwest
Deal found 6/1![Southwest logo]()
$300
Best flights from Knoxville to Key LargoDiscover carefully curated flight deals from Knoxville to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 6, 2026.
Discover carefully curated flight deals from Knoxville to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 6, 2026.
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:50 am
TYS
- MIA
1 stop5h 45m
Southwest
Sat 8/2911:35 am
MIA
- TYS
1 stop6h 05m
Southwest
Deal found 6/5![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:59 pm
TYS
- MIA
1 stop4h 10m
Delta
Wed 7/16:05 pm
MIA
- TYS
1 stop5h 49m
Delta
Deal found 6/1![Delta logo]()
$362
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:35 pm
TYS
- MIA
1 stop9h 30m
Southwest
Thu 8/276:20 am
MIA
- TYS
2 stops10h 50m
Southwest
Deal found 6/1![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:40 am
TYS
- MIA
2 stops8h 40m
Southwest
Tue 7/141:45 pm
MIA
- TYS
1 stop7h 35m
Southwest
Deal found 6/1![Southwest logo]()
$326
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:35 am
TYS
- MIA
1 stop6h 10m
Southwest
Sat 9/57:00 am
MIA
- TYS
1 stop7h 40m
Southwest
Deal found 6/5![Southwest logo]()
$336
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:10 am
TYS
- MIA
2 stops14h 05m
Southwest
Mon 7/135:25 am
MIA
- TYS
2 stops6h 35m
Southwest
Deal found 6/2![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:00 am
TYS
- MIA
1 stop12h 05m
Southwest
Sun 8/96:45 am
MIA
- TYS
1 stop8h 15m
Southwest
Deal found 6/4![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:40 am
TYS
- MIA
1 stop7h 55m
Southwest
Sun 7/55:35 am
MIA
- TYS
1 stop10h 10m
Southwest
Deal found 6/3![Southwest logo]()
$388
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:30 am
TYS
- MIA
2 stops7h 05m
Southwest
Fri 7/107:15 am
MIA
- TYS
2 stops14h 00m
Southwest
Deal found 6/5![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:30 am
TYS
- MIA
2 stops7h 05m
Southwest
Sun 7/55:35 am
MIA
- TYS
1 stop10h 10m
Southwest
Deal found 6/4![Southwest logo]()
$395
Last-minute flights from Knoxville to Key LargoDiscover last-minute flight deals from Knoxville to Key Largo. Data last updated June 6, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Key Largo. Data last updated June 6, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:32 pm
TYS
- MIA
1 stop9h 22m
Frontier
Wed 7/16:00 am
MIA
- TYS
1 stop13h 37m
Frontier
Deal found 6/1![Frontier logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/612:53 pm
TYS
- MIA
1 stop9h 26m
Multiple Airlines
Fri 7/102:56 pm
MIA
- TYS
2 stops19h 01m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:07 pm
TYS
- MIA
1 stop6h 14m
American Airlines
Wed 7/159:45 pm
MIA
- TYS
Nonstop2h 14m
American Airlines
Deal found 6/5![American Airlines logo]()
$275
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:10 am
TYS
- MIA
1 stop6h 15m
Southwest
Wed 7/151:45 pm
MIA
- TYS
1 stop7h 35m
Southwest
Deal found 6/5![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:44 pm
TYS
- MIA
1 stop28h 42m
Multiple Airlines
Sun 7/123:39 pm
MIA
- TYS
1 stop25h 03m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:44 pm
TYS
- MIA
1 stop28h 42m
Multiple Airlines
Mon 7/138:30 am
MIA
- TYS
2 stops13h 30m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/193:38 pm
TYS
- MIA
2 stops22h 15m
Multiple Airlines
Thu 7/233:39 pm
MIA
- TYS
1 stop25h 03m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$310
This Frontier deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:19 pm
TYS
- MIA
1 stop9h 32m
Frontier
Mon 7/276:00 am
MIA
- TYS
1 stop13h 24m
Frontier
Deal found 6/3![Frontier logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/263:38 pm
TYS
- MIA
1 stop28h 48m
Multiple Airlines
Fri 7/318:30 am
MIA
- TYS
2 stops13h 30m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$274
One-way flights from Knoxville to Key LargoSearch for one-way flight options from Knoxville to Key Largo. Find affordable one-way fares based on user searches. Data last updated June 6, 2026.
Search for one-way flight options from Knoxville to Key Largo. Find affordable one-way fares based on user searches. Data last updated June 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/263:38 pm
TYS
- MIA
1 stop28h 48m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:20 pm
TYS
- MIA
2 stops25h 10m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$128
This Priceline deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:32 pm
TYS
- MIA
1 stop9h 22m
Frontier
Deal found 6/4![Frontier logo]()
$129
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
TYS
- MIA
Nonstop2h 13m
American Airlines
Deal found 6/3![American Airlines logo]()
$133
This Frontier deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:32 pm
TYS
- MIA
1 stop9h 22m
Frontier
Deal found 6/4![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:05 pm
TYS
- MIA
2 stops32h 00m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:15 am
TYS
- MIA
2 stops36h 10m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:46 pm
TYS
- MIA
2 stops27h 27m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$141
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:12 pm
TYS
- MIA
1 stop6h 35m
Delta
Deal found 6/2![Delta logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:52 pm
TYS
- MIA
2 stops41h 24m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$146
Find flight deals from Knoxville to Key Largo
Keep the following information in mind while searching for Knoxville to Key Largo flight deals. Data was last updated June 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $262 (Kiwi.com) |
One-way from | $122 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $412 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
Use the filters below to find and compare flights from Knoxville to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Sat 8/22
7:50 am-1:35 pm
1 stop5h 45m
Miami
Sat 8/29
11:35 am-5:40 pm
1 stop6h 05m
$305
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Thu 8/20
12:35 pm-10:05 pm
1 stop9h 30m
Miami
Thu 8/27
6:20 am-5:10 pm
2 stops10h 50m
$316
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Mon 7/13
6:40 am-3:20 pm
2 stops8h 40m
Miami
Tue 7/14
1:45 pm-9:20 pm
1 stop7h 35m
$326
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Sun 8/30
7:35 am-1:45 pm
1 stop6h 10m
Miami
Sat 9/5
7:00 am-2:40 pm
1 stop7h 40m
$336
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Tue 7/7
8:10 am-10:15 pm
2 stops14h 05m
Miami
Mon 7/13
5:25 am-12:00 pm
2 stops6h 35m
$337
Quickest round-trip
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Tue 6/23
1:59 pm-6:09 pm
1 stop4h 10m
Miami
Wed 7/1
6:05 pm-11:54 pm
1 stop5h 49m
$362
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Sat 8/1
8:00 am-8:05 pm
1 stop12h 05m
Miami
Sun 8/9
6:45 am-3:00 pm
1 stop8h 15m
$368
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Thu 7/2
6:40 am-2:35 pm
1 stop7h 55m
Miami
Sun 7/5
5:35 am-3:45 pm
1 stop10h 10m
$388
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Fri 7/3
7:30 am-2:35 pm
2 stops7h 05m
Miami
Fri 7/10
7:15 am-9:15 pm
2 stops14h 00m
$390
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Fri 7/3
7:30 am-2:35 pm
2 stops7h 05m
Miami
Sun 7/5
5:35 am-3:45 pm
1 stop10h 10m
$395
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Knoxville with our price prediction graph.
TYS-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Key Largo
TYS-KE9
TYS-MIA
What is the cheapest time of day to fly from TYS to KE9?
Find hourly flight availability from Knoxville to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 6, 2026.
A simple way to save on the total cost of your ticket is to fly from Knoxville to Key Largo at noon. If you’re flexible enough to do this you can expect to save up to 44% on your trip compared to booking a flight in the evening.
Weekly flight availability from Knoxville to Key Largo
Explore weekly flight availability from Knoxville to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 6, 2026.
The most flights from TYS to KE9 are scheduled on a Thursday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Knoxville to Key Largo?
What is the cheapest day to fly from Knoxville to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from Knoxville to Key Largo. Price data was last updated on May 30, 2026.
Travelers seeking maximum savings on their Knoxville to Key Largo flight should consider departing on Monday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated June 6, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAllegiant Air from Knoxville to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Knoxville
Popular flights
Top destinations
Alternative routes for Knoxville to Key Largo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Key Largo by cabin class
Find flights from Knoxville to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Key Largo flights
Browse other Knoxville and Key Largo flight options. Last updated on June 6, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on June 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Key Largo flights
Consider these flights traveling from Knoxville to Key Largo.
Top 4 airlines flying from Knoxville to Key Largo
Discover the top 4 airlines that operate flights from Knoxville to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$82 | Average$206 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$178 | Average$431 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$227 | Average$398 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$372 | FlexibilityNo cancel fee | On-time63% |