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Key Largo

$61+ Cheap flights from Knoxville (TYS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MIA
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key Largo are usually found in February or July, booked 42 days in advance, depart on a Friday or Saturday and return on a Tuesday

Cheap flight deals from Knoxville to Key Largo

Keep the following information in mind while searching for Knoxville to Key Largo flight deals. Data was last updated November 13, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$179
(American Airlines)

One-way from

$61
(Frontier)

Popular in

May

Cheapest in

February

Average price

$406
Provider with most accurate pricing for Knoxville McGhee Tyson-Miami flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Miami flights.
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From Knoxville McGhee Tyson to Key Largo
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One-way flight from Knoxville McGhee Tyson to Key Largo
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Knoxville to Key Largo

Cheapest flights from Knoxville to Key Largo
Explore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:40 amTYS - MIA
1 stop3h 47mDelta
Wed 12/178:05 amMIA - TYS
1 stop6h 47mDelta
Deal found 11/12$193
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:09 pmTYS - MIA
2 stops23h 46mMultiple Airlines
Mon 12/157:05 amMIA - TYS
1 stop12h 09mMultiple Airlines
Deal found 11/13$207
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:23 pmTYS - MIA
1 stop25h 22mMultiple Airlines
Wed 12/109:03 pmMIA - TYS
2 stops19h 30mMultiple Airlines
Deal found 11/12$213
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:03 pmTYS - MIA
Nonstop2h 17mAmerican Airlines
Sat 12/139:34 pmMIA - TYS
Nonstop2h 23mAmerican Airlines
Deal found 11/12$218
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/69:00 amTYS - MIA
2 stops29h 49mMultiple Airlines
Sun 12/146:09 pmMIA - TYS
1 stop25h 05mMultiple Airlines
Deal found 11/12$232
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:23 amTYS - MIA
2 stops23h 10mMultiple Airlines
Wed 12/106:00 amMIA - TYS
1 stop31h 11mMultiple Airlines
Deal found 11/11$237
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amTYS - MIA
Nonstop2h 17mAmerican Airlines
Mon 12/155:45 amMIA - TYS
1 stop4h 09mAmerican Airlines
Deal found 11/13$250
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:40 amTYS - MIA
1 stop3h 47mDelta
Mon 12/157:30 pmMIA - TYS
1 stop3h 58mDelta
Deal found 11/13$259
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amTYS - MIA
Nonstop2h 17mAmerican Airlines
Wed 12/102:14 pmMIA - TYS
Nonstop2h 19mAmerican Airlines
Deal found 11/12$261

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Knoxville to Key Largo that are best for you.

Fly from

Knoxville

Fly to

Key Largo

Route

Depart

Return

Price

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 1/13

5:30 am-12:14 pm

1 stop6h 44m

Miami

Sat 1/17

8:15 am-3:11 pm

1 stop6h 56m

$199

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 1/3

2:23 pm-12:20 pm

1 stop21h 57m

Miami

Wed 1/7

5:07 pm-5:53 pm

2 stops24h 46m

$201

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 1/23

6:20 am-8:38 am

Nonstop2h 18m

Miami

Sat 1/31

2:37 pm-5:06 pm

Nonstop2h 29m

$208

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 12/6

5:03 pm-7:20 pm

Nonstop2h 17m

Miami

Sat 12/13

9:34 pm-11:57 pm

Nonstop2h 23m

$218

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 12/10

6:00 am-8:17 am

Nonstop2h 17m

Miami

Sat 12/13

6:00 am-1:05 pm

1 stop7h 05m

$228

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 12/6

10:15 am-9:22 am

1 stop23h 07m

Miami

Sun 12/14

6:09 pm-7:14 pm

1 stop25h 05m

$240

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 2/5

4:06 pm-8:44 pm

1 stop4h 38m

Miami

Tue 2/10

9:24 am-4:19 pm

1 stop6h 55m

$249

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 2/6

11:54 am-9:10 pm

1 stop9h 16m

Miami

Tue 2/10

11:33 am-8:22 pm

1 stop8h 49m

$249

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 1/23

5:30 am-10:40 am

1 stop5h 10m

Miami

Sat 1/31

7:15 am-11:10 am

1 stop3h 55m

$249

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Mon 12/8

4:52 pm-5:19 am

1 stop12h 27m

$61

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 18 results
1
2

Best time to book a flight from Knoxville to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key Largo

How far ahead should I book a flight from Knoxville to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Key Largo. Price data was last updated on November 7, 2025.

Booking 42 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Key Largo?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Key Largo (average of $78). Flying from Knoxville to Key Largo in December is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to KE9?

Find hourly flight availability from Knoxville to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Key Largo in the afternoon. If you’re flexible enough to do this you can expect to save up to 46% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Knoxville to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Key Largo. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Knoxville to Key Largo flight should consider departing on Monday afternoons when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Key Largo

Explore weekly flight availability from Knoxville to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 13, 2025.

The most flights from TYS to KE9 are scheduled on a Tuesday (4 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated November 13, 2025.
Get a feel of what it's like to fly with Delta, American Airlines, and Allegiant Air from Knoxville to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Allegiant Air
7.2
Good
698 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Key Largo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Key Largo. You should not have trouble finding flights to Key Largo from McGhee Tyson; the airport handles an average of 3 outbound flights to Key Largo per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Knoxville airport to Key Largo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How popular is this Knoxville to Key Largo flight route?

    Within the past month, 4 users have taken a look at flights from Knoxville McGhee Tyson to Key Largo.

  • How long is the flight from Knoxville to Key Largo?

    A quick flight from Knoxville to Key Largo can take about 2h 18m. Delta provides one of the quickest options available for as low as $208. Airlines will cover a distance of 725 mi. This flight may include one or multiple stops.

  • What are the most reliable airlines from Knoxville to Key Largo?

    Consider Qatar Airways (94%), American Airlines (90%) or Envoy Air (90%) when booking your flight. These represent the most reliable airlines when flying from Knoxville to Key Largo.

  • What are the cheapest flights from Knoxville to Key Largo?

    Looking for the cheapest flight from Knoxville to Key Largo? While on average our users pay $389, our data indicates the cheapest price to be $148. The most popular route (Knoxville McGhee Tyson - Miami), is priced around $193.

  • Can I find deals for flights from Knoxville to Key Largo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key Largo.

  • Can I find deals for business class flights from Knoxville to Key Largo?

    Yes. Cheapflights offers flight deals from Knoxville to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Key Largo?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Key Largo (average of $78). Flying from Knoxville to Key Largo in December is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Knoxville to Key Largo

Discover the top 3 airlines that operate flights from Knoxville to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$80Average$193FlexibilityNo cancel feeOn-time88%
DeltaCheapest$182Average$383FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$238Average$395FlexibilityNo cancel feeOn-time71%

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