$86+ Cheap flights from Knoxville (TYS) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MIA
Mar 24 — Mar 311
1 adult, Economy
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Find cheap flights from Knoxville to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key Largo are usually found in April or July, booked 82 days in advance, depart on a Friday or Monday and return on a Wednesday
Cheap flight deals from Knoxville to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to Key LargoExplore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
Explore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
Thu 4/167:00 am
MIA
- TYS
1 stop8h 33m
Frontier
Deal found 2/19![Frontier logo]()
$181
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
TYS
- MIA
Nonstop2h 12m
American Airlines
Wed 3/259:43 pm
MIA
- TYS
Nonstop2h 16m
American Airlines
Deal found 2/18![American Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:50 am
TYS
- MIA
1 stop6h 35m
Southwest
Wed 3/256:55 am
MIA
- TYS
1 stop10h 45m
Southwest
Deal found 2/18![Southwest logo]()
$204
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:30 pm
TYS
- MIA
2 stops9h 15m
Southwest
Tue 3/246:10 am
MIA
- TYS
2 stops11h 30m
Southwest
Deal found 2/21![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:53 pm
TYS
- MIA
1 stop28h 04m
Multiple Airlines
Wed 3/48:37 pm
MIA
- TYS
1 stop15h 25m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$214
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
Mon 4/135:50 am
MIA
- TYS
1 stop9h 38m
Frontier
Deal found 2/19![Frontier logo]()
$217
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1712:03 pm
TYS
- MIA
1 stop5h 18m
Delta
Tue 3/246:00 am
MIA
- TYS
1 stop5h 17m
Delta
Deal found 2/21![Delta logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1211:27 am
TYS
- MIA
1 stop13h 47m
Multiple Airlines
Wed 4/151:10 pm
MIA
- TYS
2 stops26h 31m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$223
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:05 am
TYS
- MIA
1 stop5h 35m
Southwest
Sat 5/26:35 am
MIA
- TYS
2 stops11h 55m
Southwest
Deal found 2/19![Southwest logo]()
$233
Best flights from Knoxville to Key LargoDiscover carefully curated flight deals from Knoxville to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
Discover carefully curated flight deals from Knoxville to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
TYS
- MIA
Nonstop2h 12m
American Airlines
Wed 3/259:43 pm
MIA
- TYS
Nonstop2h 16m
American Airlines
Deal found 2/18![American Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:30 pm
TYS
- MIA
2 stops9h 15m
Southwest
Wed 3/256:55 am
MIA
- TYS
1 stop10h 45m
Southwest
Deal found 2/18![Southwest logo]()
$210
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:00 pm
TYS
- MIA
1 stop5h 54m
Delta
Sat 4/256:15 pm
MIA
- TYS
1 stop5h 39m
Delta
Deal found 2/19![Delta logo]()
$331
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:40 am
TYS
- MIA
2 stops9h 25m
Southwest
Wed 4/156:15 am
MIA
- TYS
2 stops8h 05m
Southwest
Deal found 2/19![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:15 am
TYS
- MIA
1 stop6h 00m
Southwest
Mon 5/256:40 am
MIA
- TYS
2 stops11h 30m
Southwest
Deal found 2/18![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:40 am
TYS
- MIA
1 stop10h 35m
Southwest
Sat 5/169:30 am
MIA
- TYS
1 stop9h 00m
Southwest
Deal found 2/19![Southwest logo]()
$302
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1012:15 pm
TYS
- MIA
1 stop9h 45m
Southwest
Sat 4/186:35 am
MIA
- TYS
2 stops11h 55m
Southwest
Deal found 2/19![Southwest logo]()
$307
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:35 am
TYS
- MIA
1 stop8h 45m
Southwest
Sat 5/96:35 am
MIA
- TYS
2 stops11h 55m
Southwest
Deal found 2/19![Southwest logo]()
$307
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1212:15 pm
TYS
- MIA
1 stop9h 45m
Southwest
Sat 4/186:35 am
MIA
- TYS
1 stop6h 45m
Southwest
Deal found 2/20![Southwest logo]()
$320
Last-minute flights from Knoxville to Key LargoDiscover last-minute flight deals from Knoxville to Key Largo. Data last updated February 22, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Key Largo. Data last updated February 22, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:53 pm
TYS
- MIA
1 stop28h 04m
Multiple Airlines
Wed 3/48:37 pm
MIA
- TYS
1 stop15h 25m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:53 pm
TYS
- MIA
1 stop17h 57m
Multiple Airlines
Tue 3/37:09 pm
MIA
- TYS
2 stops23h 17m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$241
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:05 am
TYS
- MIA
1 stop6h 19m
Delta
Wed 3/257:05 am
MIA
- TYS
1 stop4h 12m
Delta
Deal found 2/21![Delta logo]()
$219
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
TYS
- MIA
Nonstop2h 12m
American Airlines
Wed 3/259:43 pm
MIA
- TYS
Nonstop2h 16m
American Airlines
Deal found 2/18![American Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:50 am
TYS
- MIA
1 stop6h 35m
Southwest
Wed 3/256:55 am
MIA
- TYS
1 stop10h 45m
Southwest
Deal found 2/18![Southwest logo]()
$204
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:30 pm
TYS
- MIA
2 stops9h 15m
Southwest
Tue 3/246:10 am
MIA
- TYS
2 stops11h 30m
Southwest
Deal found 2/21![Southwest logo]()
$209
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:15 pm
TYS
- MIA
1 stop7h 28m
American Airlines
Tue 3/249:43 pm
MIA
- TYS
Nonstop2h 16m
American Airlines
Deal found 2/21![American Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 am
TYS
- MIA
1 stop27h 34m
Multiple Airlines
Thu 3/265:05 am
MIA
- TYS
2 stops15h 33m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$253
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:20 pm
TYS
- MIA
1 stop13h 18m
Frontier
Fri 4/35:50 am
MIA
- TYS
1 stop9h 38m
Frontier
Deal found 2/19![Frontier logo]()
$250
One-way flights from Knoxville to Key LargoSearch for one-way flight options from Knoxville to Key Largo. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
Search for one-way flight options from Knoxville to Key Largo. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
Deal found 2/19![Frontier logo]()
$86
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:50 am
TYS
- MIA
1 stop6h 35m
Southwest
Deal found 2/19![Southwest logo]()
$100
This Priceline deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:13 pm
TYS
- MIA
1 stop9h 01m
Frontier
Deal found 2/18![Frontier logo]()
$101
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:30 pm
TYS
- MIA
2 stops9h 15m
Southwest
Deal found 2/18![Southwest logo]()
$105
This Priceline deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:28 pm
TYS
- MIA
1 stop12h 37m
Frontier
Deal found 2/20![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1211:27 am
TYS
- MIA
1 stop13h 47m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$113
This Priceline deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/234:20 pm
TYS
- MIA
1 stop13h 18m
Frontier
Deal found 2/20![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:27 am
TYS
- MIA
2 stops24h 46m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:54 pm
TYS
- MIA
2 stops13h 40m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:27 am
TYS
- MIA
2 stops30h 30m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$120
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:20 pm
TYS
- MIA
1 stop13h 18m
Frontier
Deal found 2/19![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/232:06 pm
TYS
- MIA
2 stops30h 01m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$122
Find flight deals from Knoxville to Key Largo
Keep the following information in mind while searching for Knoxville to Key Largo flight deals. Data was last updated February 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $181 (Frontier) |
One-way from | $86 (Frontier) |
Popular in | March |
Cheapest in | April |
Average price | $400 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Knoxville to Key Largo that are best for you.
Fly from
Knoxville
Fly to
Key Largo
Route
Depart
Return
Price
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Wed 3/18
6:00 am-8:12 am
Nonstop2h 12m
Miami
Wed 3/25
9:43 pm-11:59 pm
Nonstop2h 16m
$199
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Wed 3/18
12:30 pm-9:45 pm
2 stops9h 15m
Miami
Wed 3/25
6:55 am-5:40 pm
1 stop10h 45m
$210
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Sun 4/12
6:40 am-4:05 pm
2 stops9h 25m
Miami
Wed 4/15
6:15 am-2:20 pm
2 stops8h 05m
$269
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Tue 5/19
8:15 am-2:15 pm
1 stop6h 00m
Miami
Mon 5/25
6:40 am-6:10 pm
2 stops11h 30m
$273
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Sun 5/10
6:40 am-5:15 pm
1 stop10h 35m
Miami
Sat 5/16
9:30 am-6:30 pm
1 stop9h 00m
$302
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Fri 4/10
12:15 pm-10:00 pm
1 stop9h 45m
Miami
Sat 4/18
6:35 am-6:30 pm
2 stops11h 55m
$307
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Mon 5/4
6:35 am-3:20 pm
1 stop8h 45m
Miami
Sat 5/9
6:35 am-6:30 pm
2 stops11h 55m
$307
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Sun 4/12
12:15 pm-10:00 pm
1 stop9h 45m
Miami
Sat 4/18
6:35 am-1:20 pm
1 stop6h 45m
$320
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Fri 4/17
7:00 pm-12:54 am
1 stop5h 54m
Miami
Sat 4/25
6:15 pm-11:54 pm
1 stop5h 39m
$331
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Mon 3/2
8:13 pm-5:14 am
1 stop9h 01m
$101
Showing 1-10 of 17 results
Best time to book a flight from Knoxville to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Knoxville with our price prediction graph.
TYS-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Key Largo
TYS-KE9
TYS-MIA
How far ahead should I book a flight from Knoxville to Key Largo?
Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Key Largo. Price data was last updated on February 20, 2026.
Booking 82 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Knoxville to Key Largo?
Currently, February is the cheapest month in which you can book a flight from Knoxville to Key Largo (average of $78). Flying from Knoxville to Key Largo in January is currently the most expensive (average of $89). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to KE9?
Find hourly flight availability from Knoxville to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2026.
A simple way to save on the total cost of your ticket is to fly from Knoxville to Key Largo at noon. If you’re flexible enough to do this you can expect to save up to 50% on your trip compared to booking a flight in the evening.
What is the cheapest day to fly from Knoxville to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from Knoxville to Key Largo. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their Knoxville to Key Largo flight should consider departing on Monday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Knoxville to Key Largo
Explore weekly flight availability from Knoxville to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 22, 2026.
The most flights from TYS to KE9 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated February 22, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Knoxville to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Knoxville and Key Largo flights
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Top 4 airlines flying from Knoxville to Key Largo
Discover the top 4 airlines that operate flights from Knoxville to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$84 | Average$195 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$115 | Average$420 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$229 | Average$389 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$278 | Average$353 | FlexibilityNo cancel fee | On-time63% |