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Key Largo

$116+ Cheap flights from Knoxville (TYS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MIA
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key Largo are usually found in August or July, booked 11 days in advance, depart on a Monday or Friday and return on a Tuesday

Cheap flight deals from Knoxville to Key Largo

Keep the following information in mind while searching for Knoxville to Key Largo flight deals. Data was last updated June 12, 2025.

Round-trip from

$159
(American Airlines)

One-way from

$136
(Mytrip)

Popular in

May

Cheapest in

August

Average price

$395
From Knoxville McGhee Tyson to Key Largo
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One-way flight from Knoxville McGhee Tyson to Key Largo
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Highest demand for flights based on searches. 6% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Knoxville to Key Largo

Cheapest flights from Knoxville to Key Largo
Explore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:11 pmTYS - MIA
Nonstop2h 09mAmerican Airlines
Wed 10/293:30 pmMIA - TYS
Nonstop2h 10mAmerican Airlines
Deal found 6/10$159
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/96:14 pmTYS - MIA
1 stop6h 10mDelta
Tue 9/1610:20 amMIA - TYS
1 stop4h 45mDelta
Deal found 6/12$179
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:00 amTYS - MIA
1 stop10h 45mMultiple Airlines
Mon 9/810:40 amMIA - TYS
1 stop12h 34mMultiple Airlines
Deal found 6/10$193
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/218:36 pmTYS - MIA
1 stop9h 54mFrontier
Sun 8/316:00 amMIA - TYS
1 stop13h 41mFrontier
Deal found 6/10$256
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/97:00 amTYS - MIA
1 stop8h 14mUnited Airlines
Tue 8/191:25 pmMIA - TYS
2 stops10h 32mUnited Airlines
Deal found 6/12$392

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Knoxville to Key Largo that are best for you.

Fly from

Knoxville

Fly to

Key Largo

Route

Depart

Return

Price

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 10/8

6:11 pm-8:20 pm

Nonstop2h 09m

Miami

Wed 10/29

3:30 pm-5:40 pm

Nonstop2h 10m

$159

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 9/9

6:14 pm-12:24 am

1 stop6h 10m

Miami

Tue 9/16

10:20 am-3:05 pm

1 stop4h 45m

$179

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 9/4

9:00 am-7:45 pm

1 stop10h 45m

Miami

Mon 9/8

10:40 am-11:14 pm

1 stop12h 34m

$193

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 8/21

8:36 pm-6:30 am

1 stop9h 54m

Miami

Sun 8/31

6:00 am-7:41 pm

1 stop13h 41m

$256

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 8/9

7:00 am-3:14 pm

1 stop8h 14m

Miami

Tue 8/19

1:25 pm-11:57 pm

2 stops10h 32m

$392

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 7/9

7:10 am-9:15 am

1 stop26h 05m

$116

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sun 8/3

5:25 pm-6:30 am

1 stop13h 05m

$189

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 10/28

7:20 pm-11:14 am

1 stop15h 54m

$264

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 7/9

5:30 am-10:52 am

1 stop5h 22m

$289

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 6/27

6:00 am-8:10 am

Nonstop2h 10m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Knoxville to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key Largo

How far ahead should I book a flight from Knoxville to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Key Largo. Price data was last updated on June 9, 2025.

Booking 11 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Key Largo (average of $228). Flying from Knoxville to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to KE9?

Find hourly flight availability from Knoxville to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Key Largo as you normally would.

What is the cheapest day to fly from Knoxville to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Key Largo flight should consider departing on Wednesday evenings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Key Largo by month

Plan your trip to Key Largo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key Largo ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Key Largo when rainfall is around 1.6 in.

Temperature in Key Largo by month

Plan your trip to Key Largo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key Largo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated June 12, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Knoxville to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Frontier
5.9
Fair
3,295 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Key Largo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Key Largo. You should not have trouble finding flights to Key Largo from McGhee Tyson; the airport handles an average of 1 outbound flight to Key Largo per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Knoxville airport to Key Largo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How popular is this Knoxville to Key Largo flight route?

    Within the past month, 2 users have taken a look at flights from Knoxville McGhee Tyson to Key Largo.

  • What are the cheapest airlines to fly from Knoxville to Key Largo one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $189. Delta flights start at $289 while deals on United Airlines start at $315 one-way.

  • What are the most reliable airlines from Knoxville to Key Largo?

    Consider Envoy Air (92%), American Airlines (84%) or Qatar Airways (84%) when booking your flight. These represent the most reliable airlines when flying from Knoxville to Key Largo.

  • What are the cheapest flights from Knoxville to Key Largo?

    Looking for the cheapest flight from Knoxville to Key Largo? While on average our users pay $681, our data indicates the cheapest price to be $79. The most popular route (Knoxville McGhee Tyson - Miami), is priced around $189.

  • Can I find deals for flights from Knoxville to Key Largo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key Largo.

  • Can I find deals for business class flights from Knoxville to Key Largo?

    Yes. Cheapflights offers flight deals from Knoxville to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Key Largo (average of $228). Flying from Knoxville to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Knoxville to Key Largo

Discover the top 3 airlines that operate flights from Knoxville to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$78Average$199FlexibilityNo cancel feeOn-time88%
DeltaCheapest$178Average$395FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$229Average$395FlexibilityNo cancel feeOn-time71%

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