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Key Largo

$106+ Cheap flights from Knoxville (TYS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MIA
Aug 30 — Sep 61
Sun 8/30
Sun 9/6
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key Largo are usually found in February or January, booked 74 days in advance, depart on a Friday or Saturday and return on a Wednesday

Cheap flight deals from Knoxville to Key Largo

Cheapest flights from Knoxville to Key Largo
Explore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:55 pm
TYS
-
MIA
2 stops34h 10m
Multiple Airlines
Thu 8/278:50 pm
MIA
-
TYS
1 stop21h 45m
Multiple Airlines
Deal found 7/28$196
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:26 pm
TYS
-
MIA
1 stop25h 07m
Multiple Airlines
Thu 8/278:50 pm
MIA
-
TYS
1 stop21h 45m
Multiple Airlines
Deal found 7/30$197
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2312:55 pm
TYS
-
MIA
2 stops27h 26m
Multiple Airlines
Thu 8/278:50 pm
MIA
-
TYS
1 stop21h 45m
Multiple Airlines
Deal found 7/29$202
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:50 pm
TYS
-
MIA
2 stops27h 31m
Multiple Airlines
Thu 8/278:50 pm
MIA
-
TYS
1 stop21h 45m
Multiple Airlines
Deal found 7/29$212
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/131:19 pm
TYS
-
MIA
2 stops21h 11m
Multiple Airlines
Sun 9/208:50 pm
MIA
-
TYS
1 stop22h 44m
Multiple Airlines
Deal found 7/29$238
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:54 am
TYS
-
MIA
2 stops28h 30m
Multiple Airlines
Sun 9/208:50 pm
MIA
-
TYS
1 stop22h 44m
Multiple Airlines
Deal found 7/29$247
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:55 pm
TYS
-
MIA
2 stops18h 37m
Multiple Airlines
Sun 9/138:50 pm
MIA
-
TYS
1 stop22h 44m
Multiple Airlines
Deal found 7/30$248
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:20 am
TYS
-
MIA
2 stops15h 49m
Multiple Airlines
Sun 9/138:50 pm
MIA
-
TYS
1 stop22h 44m
Multiple Airlines
Deal found 7/30$254
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:54 pm
TYS
-
MIA
2 stops30h 44m
Multiple Airlines
Sun 10/48:50 pm
MIA
-
TYS
1 stop24h 31m
Multiple Airlines
Deal found 7/30$255

Find flight deals from Knoxville to Key Largo

Keep the following information in mind while searching for Knoxville to Key Largo flight deals. Data was last updated July 31, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$196
(Kiwi.com)

One-way from

$106
(Kiwi.com)

Popular in

March

Cheapest in

February

Average price

$420
Provider with most accurate pricing for Knoxville McGhee Tyson-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Miami flights.
Search Deals
From Knoxville McGhee Tyson to Key Largo
Search Deals
One-way flight from Knoxville McGhee Tyson to Key Largo
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2026.
Use the filters below to find and compare flights from Knoxville to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Mon 8/24

12:40 pm-10:05 pm

1 stop9h 25m

Miami

Thu 8/27

7:00 am-5:10 pm

1 stop10h 10m

$298

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 11/14

8:15 am-4:10 pm

1 stop7h 55m

Miami

Thu 11/19

6:50 am-4:40 pm

1 stop9h 50m

$316

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 9/9

7:00 am-4:05 pm

2 stops9h 05m

Miami

Wed 9/23

11:50 am-7:55 pm

1 stop8h 05m

$342

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 8/28

12:40 pm-10:05 pm

1 stop9h 25m

Miami

Fri 9/4

7:00 am-5:10 pm

1 stop10h 10m

$346

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 11/12

12:50 pm-10:00 pm

1 stop9h 10m

Miami

Sun 11/15

6:05 am-4:50 pm

2 stops10h 45m

$348

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 9/17

1:00 pm-10:10 pm

1 stop9h 10m

Miami

Sun 9/27

6:45 am-3:00 pm

1 stop8h 15m

$348

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 9/4

8:25 am-10:10 pm

2 stops13h 45m

Miami

Sun 9/6

7:55 am-1:50 pm

1 stop5h 55m

$349
Quickest round-trip

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 8/15

7:50 am-1:35 pm

1 stop5h 45m

Miami

Sat 8/22

7:00 am-2:40 pm

1 stop7h 40m

$372

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Thu 11/5

12:50 pm-10:15 pm

2 stops9h 25m

Miami

Sun 11/8

7:05 am-8:30 pm

2 stops13h 25m

$383

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 11/4

1:00 pm-10:10 pm

1 stop9h 10m

Miami

Sun 11/8

7:05 am-8:30 pm

2 stops13h 25m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Knoxville to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key Largo

What is the cheapest time of day to fly from TYS to KE9?

Find hourly flight availability from Knoxville to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2026.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Key Largo at noon. If you’re flexible enough to do this you can expect to save up to 44% on your trip compared to booking a flight in the evening.

Weekly flight availability from Knoxville to Key Largo

Explore weekly flight availability from Knoxville to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 31, 2026.

The most flights from TYS to KE9 are scheduled on a Thursday (3 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Knoxville to Key Largo?

Airfare is below average for this route at the moment.
Knoxville to Key Largo flights typically cost between $289 and $435 in August.
The cheapest round-trip price found within the last 5 days was $196 on Multiple Airlines (Aug 20-Aug 27).

What is the cheapest day to fly from Knoxville to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Key Largo. Price data was last updated on July 25, 2026.

Travelers seeking maximum savings on their Knoxville to Key Largo flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated July 31, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAllegiant Air from Knoxville to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,226 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
Southwest
8.0
Very good
4,226 reviews
Southwest
8.0
Very good
4,226 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
Delta
7.8
Good
8,492 reviews
Southwest
8.0
Very good
4,226 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
Allegiant Air
7.3
Good
678 reviews
Southwest
8.0
Very good
4,226 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
American Airlines
7.1
Good
11,846 reviews
Southwest
8.0
Very good
4,226 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Key Largo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Key Largo. You should not have trouble finding flights to Key Largo from McGhee Tyson; the airport handles an average of 2 outbound flights to Key Largo per day. You should also have plenty of airline options to choose from since 4 airlines have flights from the Knoxville airport to Key Largo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How popular is this Knoxville to Key Largo flight route?

    Within the past month, 32 users have taken a look at flights from Knoxville McGhee Tyson to Key Largo.

  • How long is the flight from Knoxville to Key Largo?

    A quick flight from Knoxville to Key Largo can take about 7h 55m. Southwest provides one of the quickest options available for as low as $316. Airlines will cover a distance of 725 mi.

  • What are the cheapest airlines to fly from Knoxville to Key Largo one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $74. Delta flights start at $115 while deals on Southwest start at $122 one-way.

  • What are the most reliable airlines from Knoxville to Key Largo?

    Consider Envoy Air (94%), Qatar Airways (83%) or American Airlines (72%) when booking your flight. These represent the most reliable airlines when flying from Knoxville to Key Largo.

  • What are the cheapest flights from Knoxville to Key Largo?

    Looking for the cheapest flight from Knoxville to Key Largo? While on average our users pay $617, our data indicates the cheapest price to be $323. The most popular route (Knoxville McGhee Tyson - Miami), is priced around $197.

  • Can I find deals for flights from Knoxville to Key Largo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key Largo.

  • Can I find deals for business class flights from Knoxville to Key Largo?

    Yes. Cheapflights offers flight deals from Knoxville to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 4 airlines flying from Knoxville to Key Largo

Discover the top 4 airlines that operate flights from Knoxville to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$79Average$197FlexibilityNo cancel feeOn-time88%
DeltaCheapest$179Average$465FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$231Average$426FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$284Average$372FlexibilityNo cancel feeOn-time63%

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