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Key Largo

$80+ Cheap flights from Knoxville (TYS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MIA
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key Largo are usually found in February or April, booked 42 days in advance, depart on a Friday or Monday and return on a Wednesday

Cheap flight deals from Knoxville to Key Largo

Keep the following information in mind while searching for Knoxville to Key Largo flight deals. Data was last updated January 6, 2026.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$170
(Kiwi.com)

One-way from

$80
(Frontier)

Popular in

May

Cheapest in

February

Average price

$362
Provider with most accurate pricing for Knoxville McGhee Tyson-Miami flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Miami flights.
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From Knoxville McGhee Tyson to Key Largo
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One-way flight from Knoxville McGhee Tyson to Key Largo
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Knoxville to Key Largo

Cheapest flights from Knoxville to Key Largo
Explore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/11:39 pmTYS - MIA
1 stop29h 11mMultiple Airlines
Thu 3/56:00 amMIA - TYS
1 stop30h 00mMultiple Airlines
Deal found 1/5$170
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:36 pmTYS - MIA
Nonstop2h 16mAmerican Airlines
Sat 2/79:34 pmMIA - TYS
Nonstop2h 25mAmerican Airlines
Deal found 1/5$179
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/11:39 pmTYS - MIA
1 stop29h 11mMultiple Airlines
Sun 2/86:00 amMIA - TYS
1 stop11h 53mMultiple Airlines
Deal found 1/6$182
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:20 amTYS - MIA
Nonstop2h 18mAmerican Airlines
Tue 2/102:37 pmMIA - TYS
Nonstop2h 29mAmerican Airlines
Deal found 1/6$189
This Priceline deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:51 pmTYS - MIA
1 stop10h 23mFrontier
Mon 3/26:25 amMIA - TYS
1 stop12h 53mFrontier
Deal found 1/6$195
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/286:20 amTYS - MIA
Nonstop2h 18mAmerican Airlines
Sat 1/319:34 pmMIA - TYS
Nonstop2h 25mAmerican Airlines
Deal found 1/6$199
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/181:39 pmTYS - MIA
1 stop27h 01mMultiple Airlines
Thu 1/2911:38 amMIA - TYS
1 stop24h 27mMultiple Airlines
Deal found 1/6$208
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/38:25 amTYS - MIA
1 stop7h 02mDelta
Tue 2/107:15 amMIA - TYS
1 stop3h 53mDelta
Deal found 1/6$209
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/67:15 amTYS - MIA
1 stop30h 06mMultiple Airlines
Sun 2/158:00 amMIA - TYS
1 stop14h 25mMultiple Airlines
Deal found 1/6$211
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:53 pmTYS - MIA
1 stop28h 04mMultiple Airlines
Sat 3/76:59 pmMIA - TYS
2 stops27h 27mMultiple Airlines
Deal found 1/6$213

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Knoxville to Key Largo that are best for you.

Fly from

Knoxville

Fly to

Key Largo

Route

Depart

Return

Price

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Mon 2/2

5:24 pm-7:40 pm

Nonstop2h 16m

Miami

Sat 2/7

9:34 pm-11:59 pm

Nonstop2h 25m

$189

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 2/11

5:40 am-9:26 am

1 stop3h 46m

Miami

Sat 2/14

6:00 am-11:08 am

1 stop5h 08m

$199

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 1/28

5:40 am-9:26 am

1 stop3h 46m

Miami

Sat 1/31

7:15 am-11:08 am

1 stop3h 53m

$219

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 3/10

5:30 am-4:37 pm

2 stops11h 07m

Miami

Tue 3/17

11:30 am-8:35 pm

1 stop9h 05m

$248

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 1/24

1:05 pm-9:10 pm

1 stop8h 05m

Miami

Tue 1/27

5:50 am-11:08 am

1 stop5h 18m

$254

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 1/30

11:58 am-6:20 pm

1 stop6h 22m

Miami

Fri 2/6

7:15 am-11:08 am

1 stop3h 53m

$259

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 2/6

7:15 am-8:13 pm

1 stop12h 58m

Miami

Sun 2/15

7:09 pm-10:08 am

2 stops38h 59m

$273

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 1/23

4:00 pm-10:22 pm

1 stop6h 22m

Miami

Sat 1/31

9:34 pm-11:59 pm

Nonstop2h 25m

$294

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Sat 1/24

1:05 pm-9:10 pm

1 stop8h 05m

Miami

Mon 1/26

7:15 am-11:08 am

1 stop3h 53m

$304

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Fri 1/23

5:40 am-9:24 am

1 stop3h 44m

Miami

Tue 1/27

7:15 am-11:08 am

1 stop3h 53m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/4

Showing 1-10 of 18 results
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Best time to book a flight from Knoxville to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key Largo

How far ahead should I book a flight from Knoxville to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Key Largo. Price data was last updated on January 2, 2026.

Booking 42 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Key Largo?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Key Largo (average of $78). Flying from Knoxville to Key Largo in December is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to KE9?

Find hourly flight availability from Knoxville to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 6, 2026.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Key Largo at noon. If you’re flexible enough to do this you can expect to save up to 56% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Knoxville to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Key Largo. Price data was last updated on January 3, 2026.

Travelers seeking maximum savings on their Knoxville to Key Largo flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Key Largo

Explore weekly flight availability from Knoxville to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 6, 2026.

The most flights from TYS to KE9 are scheduled on a Tuesday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated January 6, 2026.
Get a feel of what it's like to fly with Delta, American Airlines, and Allegiant Air from Knoxville to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,017 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Delta
7.9
Good
8,017 reviews
Delta
7.9
Good
8,017 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
American Airlines
7.2
Good
11,083 reviews
Delta
7.9
Good
8,017 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Allegiant Air
7.2
Good
701 reviews
Delta
7.9
Good
8,017 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Key Largo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Key Largo. You should not have trouble finding flights to Key Largo from McGhee Tyson; the airport handles an average of 2 outbound flights to Key Largo per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Knoxville airport to Key Largo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How popular is this Knoxville to Key Largo flight route?

    Within the past month, 7 users have taken a look at flights from Knoxville McGhee Tyson to Key Largo.

  • How long is the flight from Knoxville to Key Largo?

    A quick flight from Knoxville to Key Largo can take about 2h 16m. American Airlines provides one of the quickest options available for as low as $189. Airlines will cover a distance of 725 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Knoxville to Key Largo one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $60. Delta flights start at $89 while deals on American Airlines start at $145 one-way.

  • What are the most reliable airlines from Knoxville to Key Largo?

    Consider Envoy Air (79%), Qatar Airways (78%) or American Airlines (68%) when booking your flight. These represent the most reliable airlines when flying from Knoxville to Key Largo.

  • What are the cheapest flights from Knoxville to Key Largo?

    Looking for the cheapest flight from Knoxville to Key Largo? While on average our users pay $493, our data indicates the cheapest price to be $103. The most popular route (Knoxville McGhee Tyson - Miami), is priced around $222.

  • Can I find deals for flights from Knoxville to Key Largo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key Largo.

  • Can I find deals for business class flights from Knoxville to Key Largo?

    Yes. Cheapflights offers flight deals from Knoxville to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Key Largo?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Key Largo (average of $78). Flying from Knoxville to Key Largo in December is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Knoxville to Key Largo

Discover the top 3 airlines that operate flights from Knoxville to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$81Average$188FlexibilityNo cancel feeOn-time88%
DeltaCheapest$182Average$386FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$229Average$398FlexibilityNo cancel feeOn-time71%

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