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$981+ Cheap flights from Des Moines (DSM) to Johannesburg

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Cheap flight deals from Des Moines to Johannesburg

Cheapest flights from Des Moines to Johannesburg
Explore the most affordable flight options available from Des Moines to Johannesburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/81:37 pm
DSM
-
JNB
2 stops34h 58m
American Airlines
Sun 3/1510:00 pm
JNB
-
DSM
2 stops30h 59m
American Airlines
Deal found 1/21$1,137
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:26 pm
DSM
-
JNB
2 stops32h 09m
American Airlines
Wed 3/1110:00 pm
JNB
-
DSM
2 stops27h 19m
American Airlines
Deal found 1/19$1,139
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/182:00 pm
DSM
-
JNB
2 stops33h 35m
American Airlines
Wed 2/2510:00 pm
JNB
-
DSM
2 stops33h 40m
American Airlines
Deal found 1/19$1,186
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:38 pm
DSM
-
JNB
2 stops36h 47m
American Airlines
Fri 3/1310:00 pm
JNB
-
DSM
2 stops32h 40m
American Airlines
Deal found 1/20$1,191
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:34 pm
DSM
-
JNB
2 stops29h 26m
American Airlines
Sun 9/207:25 pm
JNB
-
DSM
2 stops27h 57m
American Airlines
Deal found 1/21$1,239
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/73:58 pm
DSM
-
JNB
2 stops34h 27m
American Airlines
Sat 3/1410:00 pm
JNB
-
DSM
2 stops32h 40m
American Airlines
Deal found 1/20$1,240
This Gotogate deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:08 pm
DSM
-
JNB
2 stops38h 27m
Qatar Airways
Tue 3/312:45 pm
JNB
-
DSM
2 stops31h 11m
Qatar Airways
Deal found 1/21$1,305
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:29 pm
DSM
-
JNB
2 stops31h 56m
American Airlines
Sun 5/319:15 pm
JNB
-
DSM
2 stops29h 13m
American Airlines
Deal found 1/20$1,314

Find flight deals from Des Moines to Johannesburg

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Johannesburg (ZA1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 22, 2026.

Round-trip from

$1,137
(American Airlines)

One-way from

$981
(Qatar Airways)

Popular in

June

Cheapest in

November

Average price

$1,752
From Des Moines to Johannesburg
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One-way flight from Des Moines to Johannesburg
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Highest demand for flights based on searches. 8% potential increase in price ($166 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($45 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Johannesburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg that are best for you.

Fly from

Des Moines

Fly to

Johannesburg

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 3/8

1:37 pm-7:35 am

2 stops34h 58m

Johannesburg OR Tambo

Sun 3/15

10:00 pm-9:59 pm

2 stops30h 59m

$1,137

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/4

3:26 pm-7:35 am

2 stops32h 09m

Johannesburg OR Tambo

Wed 3/11

10:00 pm-6:19 pm

2 stops27h 19m

$1,139

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 2/18

2:00 pm-7:35 am

2 stops33h 35m

Johannesburg OR Tambo

Wed 2/25

10:00 pm-11:40 pm

2 stops33h 40m

$1,186

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 3/7

3:58 pm-10:25 am

2 stops34h 27m

Johannesburg OR Tambo

Sat 3/14

10:00 pm-11:40 pm

2 stops32h 40m

$1,289

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 3/8

7:44 pm-7:35 am

2 stops52h 51m

Johannesburg OR Tambo

Sun 3/15

10:00 pm-11:40 pm

2 stops32h 40m

$1,321

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 4/5

11:17 am-4:00 am

2 stops33h 43m

Johannesburg OR Tambo

Sun 4/12

8:55 pm-12:11 am

2 stops34h 16m

$1,325

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 6/21

6:29 pm-7:00 am

2 stops29h 31m

Johannesburg OR Tambo

Sun 7/12

7:25 pm-5:59 pm

2 stops29h 34m

$1,339

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 3/7

5:05 am-3:55 am

2 stops38h 50m

Johannesburg OR Tambo

Sat 3/14

1:45 pm-11:42 pm

2 stops40h 57m

$1,455

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 3/5

1:38 pm-7:35 am

2 stops33h 57m

Johannesburg OR Tambo

Mon 3/9

7:35 pm-11:40 pm

2 stops35h 05m

$1,503

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 3/6

1:38 pm-3:55 am

2 stops30h 17m

$981

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 16 results
1
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Best time to book a flight from Des Moines to Johannesburg

Have a flexible travel schedule? Discover the best time to fly to Johannesburg from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Johannesburg
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Johannesburg

Get insights into the airlines that provide service to Johannesburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Johannesburg. Reviews last updated January 22, 2026.
Get a feel of what it's like to fly with Delta from Des Moines to Johannesburg by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,087 reviews

Comfort

7.9

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,087 reviews
Delta
7.9
Good
8,087 reviews

Comfort

7.9

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Johannesburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Johannesburg?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Johannesburg. 1 airline have flights from Des Moines to Johannesburg on a regular basis. Booking flights from Des Moines to Johannesburg should not be difficult; the airport handles an average of 0 outbound flights to Johannesburg per day.

  • How long is the flight from Des Moines to Johannesburg?

    Airlines like American Airlines fly from Des Moines to Johannesburg in about 34h 58m. The time it takes to get you to your destination can typically vary by up to . There are 8998 mi between Des Moines and Johannesburg.

  • What is the cheapest airline to fly from Des Moines to Johannesburg round-trip?

    Delta, at $1,410, was found to be the cheapest airline from Des Moines to Johannesburg.. Delta is currently priced 17% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Johannesburg that include hotel bookings?

    Yes. In addition to deals on Des Moines to Johannesburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Johannesburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Johannesburg.

  • Can I find deals for business class flights from Des Moines to Johannesburg?

    Yes. Cheapflights offers flight deals from Des Moines to Johannesburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Des Moines to Johannesburg

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to OR Tambo flights
Omaha to OR Tambo flights
Omaha to Cape Town flights
Moline to OR Tambo flights

Top airline flying from Des Moines to Johannesburg

Discover the top airline that operate flights from Des Moines to Johannesburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$1,410Average$1,972FlexibilityNo cancel feeOn-timeN/A

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