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$1,198+ Cheap flights from Des Moines (DSM) to Johannesburg

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Cheap flight deals from Des Moines to Johannesburg

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Johannesburg (ZA1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Round-trip from

$1,234
(American Airlines)

One-way from

$1,198
(Booking.com)

Popular in

June

Cheapest in

January

Average price

$1,405
From Des Moines to Johannesburg
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One-way flight from Des Moines to Johannesburg
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Highest demand for flights based on searches. 11% potential increase in price ($227 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($59 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Des Moines to Johannesburg

Cheapest flights from Des Moines to Johannesburg
Explore the most affordable flight options available from Des Moines to Johannesburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:00 amDSM - JNB
2 stops26h 35mUnited Airlines
Sun 1/410:00 pmJNB - DSM
2 stops33h 58mUnited Airlines
Deal found 11/19$3,504
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:00 pmDSM - JNB
1 stop20h 00mDelta
Sun 1/411:59 pmJNB - DSM
2 stops30h 30mDelta
Deal found 11/19$3,965
This Mytrip deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:35 amDSM - JNB
2 stops37h 55mMultiple Airlines
Sat 1/31:25 pmJNB - DSM
2 stops41h 05mMultiple Airlines
Deal found 11/20$3,977
This Air Canada deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:35 amDSM - JNB
3 stops37h 55mAir Canada
Sun 1/48:15 pmJNB - DSM
3 stops46h 40mAir Canada
Deal found 11/20$5,607

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Johannesburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Des Moines to Johannesburg that are best for you.

Fly from

Des Moines

Fly to

Johannesburg

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 3/5

3:25 pm-7:35 am

2 stops32h 10m

Johannesburg OR Tambo

Mon 3/9

7:35 pm-10:32 pm

2 stops33h 57m

$1,234

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 4/5

5:52 pm-4:10 pm

2 stops39h 18m

Johannesburg OR Tambo

Sun 4/12

8:40 pm-10:40 pm

2 stops33h 00m

$1,504

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 4/5

10:15 am-7:40 pm

2 stops26h 25m

Johannesburg OR Tambo

Sun 4/12

9:55 pm-10:29 pm

1 stop31h 34m

$1,702

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 3/14

6:20 pm-7:35 am

2 stops30h 15m

Johannesburg OR Tambo

Fri 3/20

10:00 pm-9:53 pm

2 stops30h 53m

$1,734

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 1/9

6:24 am-7:00 pm

2 stops28h 36m

Johannesburg OR Tambo

Fri 1/16

11:59 pm-8:54 pm

2 stops28h 55m

$1,738

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 1/9

1:03 pm-7:00 pm

1 stop21h 57m

Johannesburg OR Tambo

Fri 1/16

10:00 pm-10:29 pm

2 stops32h 29m

$1,790

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 1/9

1:03 pm-7:00 pm

1 stop21h 57m

Johannesburg OR Tambo

Fri 1/16

7:20 pm-9:24 pm

2 stops34h 04m

$1,825

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 2/27

11:28 am-7:00 pm

1 stop23h 32m

Johannesburg OR Tambo

Tue 3/3

9:55 pm-4:29 pm

1 stop26h 34m

$1,882

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 1/4

6:46 pm-9:30 am

2 stops30h 44m

Johannesburg OR Tambo

Sun 1/11

10:10 am-9:50 pm

2 stops43h 40m

$1,924

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 12/22

6:35 pm-7:35 am

2 stops53h 00m

$1,198

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 17 results
1
2

Best time to book a flight from Des Moines to Johannesburg

Have a flexible travel schedule? Discover the best time to fly to Johannesburg from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Johannesburg

What is the cheapest time of day to fly from DSM to JNB?

Find hourly flight availability from Des Moines to Johannesburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

It’s optimal to fly from Des Moines to Johannesburg in the afternoon. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Des Moines to Johannesburg?

Reviews of airlines servicing Johannesburg

Get insights into the airlines that provide service to Johannesburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Johannesburg. Reviews last updated November 20, 2025.
Get a feel of what it's like to fly with Delta and United Airlines from Des Moines to Johannesburg by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,028 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Johannesburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Johannesburg?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Johannesburg. 2 airlines have flights from Des Moines to Johannesburg on a regular basis. Booking flights from Des Moines to Johannesburg should not be difficult; the airport handles an average of 0 outbound flights to Johannesburg per day.

  • How long is the flight from Des Moines to Johannesburg?

    Airlines like American Airlines, Qatar Airways, and Delta fly from Des Moines to Johannesburg in about 26h 25m. The time it takes to get you to your destination can typically vary by up to 12h 53m. There are 8998 mi between Des Moines and Johannesburg. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Johannesburg round-trip?

    United Airlines, at $1,322, was found to be the cheapest airline from Des Moines to Johannesburg. An alternate airline flying to your destination would be Delta. United Airlines is currently priced 21% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Johannesburg that include hotel bookings?

    Yes. In addition to deals on Des Moines to Johannesburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Johannesburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Johannesburg.

  • Can I find deals for business class flights from Des Moines to Johannesburg?

    Yes. Cheapflights offers flight deals from Des Moines to Johannesburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Des Moines to Johannesburg

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Cape Town flights
Des Moines to OR Tambo flights
Omaha to OR Tambo flights
Moline to OR Tambo flights

Top 2 airlines flying from Des Moines to Johannesburg

Discover the top 2 airlines that operate flights from Des Moines to Johannesburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$1,322Average$1,503FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,410Average$1,972FlexibilityNo cancel feeOn-timeN/A

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