$704+ Cheap flights from Des Moines (DSM) to Johannesburg
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Oct 1 — Oct 81
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Johannesburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Johannesburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to JohannesburgExplore the most affordable flight options available from Des Moines to Johannesburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from Des Moines to Johannesburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:26 am -
2 stops39h 29m
Wed 10/2111:10 am -
2 stops44h 04m
Deal found 8/30![Multiple Airlines logo]()
$1,383
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:26 am -
2 stops39h 29m
Tue 10/2011:10 am -
2 stops44h 04m
Deal found 8/28![Multiple Airlines logo]()
$1,389
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops44h 04m
Deal found 8/30![Multiple Airlines logo]()
$1,392
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops42h 57m
Deal found 8/31![Multiple Airlines logo]()
$1,397
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:26 am -
2 stops39h 29m
Thu 10/2211:10 am -
2 stops42h 57m
Deal found 8/31![Multiple Airlines logo]()
$1,433
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Mon 9/2111:10 am -
2 stops43h 54m
Deal found 8/31![Multiple Airlines logo]()
$1,440
This Cathay Pacific deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:29 am -
2 stops41h 26m
Sun 10/1811:10 am -
2 stops38h 45m
Deal found 8/27![Multiple Airlines logo]()
$1,445
Best flights from Des Moines to JohannesburgDiscover carefully curated flight deals from Des Moines to Johannesburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from Des Moines to Johannesburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:26 am -
2 stops39h 29m
Wed 10/2111:10 am -
2 stops44h 04m
Deal found 8/30![Multiple Airlines logo]()
$1,389
This Qatar Airways deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:26 am -
2 stops40h 44m
Mon 10/198:55 pm -
2 stops29h 05m
Deal found 8/28![Qatar Airways logo]()
$1,643
This Virgin Atlantic deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:03 pm -
1 stop21h 37m
Tue 10/209:55 pm -
1 stop31h 38m
Deal found 8/28![Virgin Atlantic logo]()
$1,766
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:03 pm -
1 stop21h 37m
Thu 10/229:55 pm -
1 stop23h 14m
Deal found 8/31![Delta logo]()
$1,767
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:26 am -
2 stops39h 29m
Tue 10/2011:10 am -
2 stops44h 04m
Deal found 8/28![Multiple Airlines logo]()
$1,389
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops44h 04m
Deal found 8/28![Multiple Airlines logo]()
$1,436
This Cathay Pacific deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/119:26 am -
2 stops39h 29m
Sun 10/1811:10 am -
2 stops44h 04m
Deal found 8/27![Multiple Airlines logo]()
$1,448
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:03 pm -
1 stop21h 37m
Tue 10/209:55 pm -
2 stops29h 45m
Deal found 8/28![Delta logo]()
$1,771
Last-minute flights from Des Moines to JohannesburgDiscover last-minute flight deals from Des Moines to Johannesburg. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Johannesburg. Data last updated September 1, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am -
2 stops24h 30m
Fri 9/42:30 pm -
3 stops28h 48m
Deal found 8/29![Ethiopian Air logo]()
$1,729
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Mon 9/2111:10 am -
2 stops43h 54m
Deal found 8/31![Multiple Airlines logo]()
$1,440
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Sun 9/2011:10 am -
2 stops43h 54m
Deal found 8/28![Multiple Airlines logo]()
$1,447
This oojo deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:22 pm -
2 stops39h 08m
Sun 9/208:20 am -
3 stops37h 00m
Deal found 8/27![Ethiopian Air logo]()
$1,586
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:11 pm -
1 stop20h 29m
Sun 9/2011:15 pm -
2 stops30h 11m
Deal found 8/28![Delta logo]()
$1,907
This Virgin Atlantic deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:31 am -
1 stop25h 09m
Mon 9/219:55 pm -
1 stop31h 31m
Deal found 8/31![Virgin Atlantic logo]()
$1,915
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:59 am -
2 stops25h 41m
Mon 9/219:55 pm -
1 stop22h 54m
Deal found 8/31![Delta logo]()
$1,921
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:00 am -
3 stops27h 30m
Sun 9/207:00 pm -
2 stops33h 28m
Deal found 8/28![United Airlines logo]()
$1,927
One-way flights from Des Moines to JohannesburgSearch for one-way flight options from Des Moines to Johannesburg. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from Des Moines to Johannesburg. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/237:29 am -
2 stops39h 56m
Deal found 8/30![Multiple Airlines logo]()
$704
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/235:45 am -
1 stop29h 25m
Deal found 8/30![Delta logo]()
$1,190
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:35 am -
3 stops54h 50m
Deal found 8/27![Multiple Airlines logo]()
$1,193
This KAYAK deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:45 pm -
2 stops30h 55m
Deal found 8/27![Lufthansa logo]()
$1,263
Find flight deals from Des Moines to Johannesburg
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Johannesburg (ZA1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 1, 2026.
Round-trip from | $1,377 (Etihad Airways) |
|---|---|
One-way from | $704 (Cathay Pacific) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Johannesburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Wed 10/14
9:26 am-7:55 am
2 stops39h 29m
Johannesburg OR Tambo
Wed 10/21
11:10 am-12:14 am
2 stops44h 04m
$1,389
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Tue 10/13
9:26 am-7:55 am
2 stops39h 29m
Johannesburg OR Tambo
Tue 10/20
11:10 am-12:14 am
2 stops44h 04m
$1,389
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Mon 10/12
9:26 am-7:45 am
2 stops39h 19m
Johannesburg OR Tambo
Mon 10/19
11:10 am-12:14 am
2 stops44h 04m
$1,436
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sun 10/11
9:26 am-7:55 am
2 stops39h 29m
Johannesburg OR Tambo
Sun 10/18
11:10 am-12:14 am
2 stops44h 04m
$1,448
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 10/15
9:26 am-9:10 am
2 stops40h 44m
Johannesburg OR Tambo
Mon 10/19
8:55 pm-7:00 pm
2 stops29h 05m
$1,643
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Tue 10/13
3:03 pm-7:40 pm
1 stop21h 37m
Johannesburg OR Tambo
Tue 10/20
9:55 pm-10:33 pm
1 stop31h 38m
$1,766
Quickest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 10/15
3:03 pm-7:40 pm
1 stop21h 37m
Johannesburg OR Tambo
Thu 10/22
9:55 pm-2:09 pm
1 stop23h 14m
$1,767
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Tue 10/13
3:03 pm-7:40 pm
1 stop21h 37m
Johannesburg OR Tambo
Tue 10/20
9:55 pm-8:40 pm
2 stops29h 45m
$1,771
Cheapest one-way
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Tue 2/23
7:29 am-7:25 am
2 stops39h 56m
$704
Quickest one-way
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Tue 2/23
5:45 am-7:10 pm
1 stop29h 25m
$1,190
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Johannesburg
Have a flexible travel schedule? Discover the best time to fly to Johannesburg from Des Moines with our price prediction graph.
DSM-ZA1
DSM-JNB
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Johannesburg
DSM-ZA1
DSM-JNB
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Johannesburg
Get insights into the airlines that provide service to Johannesburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Johannesburg. Reviews last updated September 1, 2026.
Get a feel of what it's like to fly with Delta and Qatar Airways from Des Moines to Johannesburg by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Johannesburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Des Moines
Popular flights
Alternative routes for Des Moines to Johannesburg
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Johannesburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Johannesburg by cabin class
Find flights from Des Moines to Johannesburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Johannesburg flights
Browse other Des Moines and Johannesburg flight options. Last updated on September 1, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Johannesburg
Discover the top 2 airlines that operate flights from Des Moines to Johannesburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,527 | Average$1,651 | FlexibilityNo cancel fee | On-time68% | |
| Cheapest$1,591 | Average$1,865 | FlexibilityNo cancel fee | On-timeN/A |