$925+ Cheap flights from Des Moines (DSM) to Johannesburg
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Johannesburg
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Best
Last-minute
One-way
Cheapest flights from Des Moines to JohannesburgExplore the most affordable flight options available from Des Moines to Johannesburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Des Moines to Johannesburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This Etihad Airways deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:44 pm -
2 stops34h 31m
Sat 9/199:45 am -
2 stops40h 36m
Deal found 8/22![Multiple Airlines logo]()
$1,376
This Cathay Pacific deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:26 am -
2 stops39h 29m
Wed 10/1411:10 am -
2 stops44h 04m
Deal found 8/23![Multiple Airlines logo]()
$1,397
This Cathay Pacific deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Sun 9/2011:10 am -
2 stops43h 54m
Deal found 8/25![Multiple Airlines logo]()
$1,447
This Etihad Airways deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
2 stops42h 20m
Fri 12/119:50 am -
2 stops41h 29m
Deal found 8/25![Multiple Airlines logo]()
$1,465
This Bravofly deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:01 pm -
2 stops36h 09m
Fri 10/162:05 pm -
2 stops35h 55m
Deal found 8/25![Qatar Airways logo]()
$1,471
This Cathay Pacific deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:29 am -
2 stops41h 26m
Fri 10/1611:10 am -
2 stops38h 50m
Deal found 8/25![Multiple Airlines logo]()
$1,497
This Qatar Airways deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:29 am -
2 stops37h 31m
Mon 10/198:55 pm -
2 stops29h 05m
Deal found 8/21![Qatar Airways logo]()
$1,546
This Cathay Pacific deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:29 am -
2 stops41h 26m
Thu 10/1511:10 am -
2 stops38h 45m
Deal found 8/24![Multiple Airlines logo]()
$1,577
Best flights from Des Moines to JohannesburgDiscover carefully curated flight deals from Des Moines to Johannesburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Des Moines to Johannesburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This Etihad Airways deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:44 pm -
2 stops34h 31m
Sat 9/199:45 am -
2 stops40h 36m
Deal found 8/22![Multiple Airlines logo]()
$1,376
This Qatar Airways deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:29 am -
2 stops37h 31m
Mon 10/198:55 pm -
2 stops29h 05m
Deal found 8/21![Qatar Airways logo]()
$1,546
This oojo deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:32 am -
2 stops42h 58m
Sun 9/202:30 pm -
3 stops37h 58m
Deal found 8/21![Ethiopian Air logo]()
$1,590
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:03 pm -
1 stop21h 37m
Wed 10/1411:15 pm -
2 stops26h 56m
Deal found 8/23![Delta logo]()
$1,807
This Cathay Pacific deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Sun 9/2011:10 am -
2 stops43h 54m
Deal found 8/21![Multiple Airlines logo]()
$1,447
This Cathay Pacific deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:29 am -
2 stops41h 26m
Thu 10/1511:10 am -
2 stops38h 45m
Deal found 8/24![Multiple Airlines logo]()
$1,577
This Virgin Atlantic deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:03 pm -
1 stop21h 37m
Fri 10/163:15 pm -
2 stops38h 18m
Deal found 8/25![Multiple Airlines logo]()
$1,849
Last-minute flights from Des Moines to JohannesburgDiscover last-minute flight deals from Des Moines to Johannesburg. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Johannesburg. Data last updated August 26, 2026 and is based on user searches.
This Etihad Airways deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:44 pm -
2 stops34h 31m
Sat 9/199:45 am -
2 stops40h 36m
Deal found 8/22![Multiple Airlines logo]()
$1,376
This oojo deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:24 am -
2 stops24h 06m
Sat 9/192:30 pm -
3 stops37h 58m
Deal found 8/22![Ethiopian Air logo]()
$1,662
This Air Canada deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:32 am -
3 stops38h 03m
Sat 9/197:20 pm -
3 stops33h 08m
Deal found 8/22![Air Canada logo]()
$2,123
This Cathay Pacific deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Sun 9/2011:10 am -
2 stops43h 54m
Deal found 8/25![Multiple Airlines logo]()
$1,447
This oojo deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:32 am -
2 stops42h 58m
Sun 9/202:30 pm -
3 stops37h 58m
Deal found 8/21![Ethiopian Air logo]()
$1,590
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:11 pm -
1 stop20h 29m
Sun 9/2011:15 pm -
2 stops30h 11m
Deal found 8/21![Delta logo]()
$1,906
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:54 am -
3 stops27h 36m
Sun 9/277:00 pm -
2 stops29h 48m
Deal found 8/23![United Airlines logo]()
$1,926
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:31 am -
1 stop25h 09m
Sun 9/279:55 pm -
1 stop22h 54m
Deal found 8/23![Delta logo]()
$2,606
One-way flights from Des Moines to JohannesburgSearch for one-way flight options from Des Moines to Johannesburg. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Des Moines to Johannesburg. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This Cathay Pacific deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/109:26 am -
2 stops39h 19m
Deal found 8/26![Multiple Airlines logo]()
$925
This Cathay Pacific deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:26 am -
2 stops39h 29m
Deal found 8/24![Multiple Airlines logo]()
$926
This Expedia deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:27 am -
1 stop25h 13m
Deal found 8/26![Virgin Atlantic logo]()
$1,199
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:27 am -
1 stop25h 13m
Deal found 8/24![Delta logo]()
$1,204
This Air Canada deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:24 pm -
3 stops36h 11m
Deal found 8/24![Air Canada logo]()
$1,264
Find flight deals from Des Moines to Johannesburg
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Johannesburg (ZA1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 26, 2026.
Round-trip from | $1,376 (Etihad Airways) |
|---|---|
One-way from | $925 (Cathay Pacific) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Johannesburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 9/10
2:44 pm-8:15 am
2 stops34h 31m
Johannesburg OR Tambo
Sat 9/19
9:45 am-7:21 pm
2 stops40h 36m
$1,376
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Fri 9/11
10:35 am-7:55 am
2 stops38h 20m
Johannesburg OR Tambo
Sun 9/20
11:10 am-12:04 am
2 stops43h 54m
$1,447
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 10/15
7:29 am-4:00 am
2 stops37h 31m
Johannesburg OR Tambo
Mon 10/19
8:55 pm-7:00 pm
2 stops29h 05m
$1,546
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 10/8
7:29 am-7:55 am
2 stops41h 26m
Johannesburg OR Tambo
Thu 10/15
11:10 am-6:55 pm
2 stops38h 45m
$1,577
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Fri 9/11
11:32 am-1:30 pm
2 stops42h 58m
Johannesburg OR Tambo
Sun 9/20
2:30 pm-9:28 pm
3 stops37h 58m
$1,590
Quickest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Wed 10/7
3:03 pm-7:40 pm
1 stop21h 37m
Johannesburg OR Tambo
Wed 10/14
11:15 pm-7:11 pm
2 stops26h 56m
$1,807
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Fri 10/9
3:03 pm-7:40 pm
1 stop21h 37m
Johannesburg OR Tambo
Fri 10/16
3:15 pm-10:33 pm
2 stops38h 18m
$1,849
Cheapest one-way
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sat 10/10
9:26 am-7:45 am
2 stops39h 19m
$925
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Fri 10/9
9:26 am-7:55 am
2 stops39h 29m
$926
Quickest one-way
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sat 10/10
11:27 am-7:40 pm
1 stop25h 13m
$1,199
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Johannesburg
Have a flexible travel schedule? Discover the best time to fly to Johannesburg from Des Moines with our price prediction graph.
DSM-ZA1
DSM-JNB
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Johannesburg
DSM-ZA1
DSM-JNB
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Johannesburg
Get insights into the airlines that provide service to Johannesburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Johannesburg. Reviews last updated August 26, 2026.
Get a feel of what it's like to fly with Delta and Qatar Airways from Des Moines to Johannesburg by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Johannesburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Johannesburg
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Complete your trip
Complete your trip to Johannesburg by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Johannesburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Johannesburg flights
Browse other Des Moines and Johannesburg flight options. Last updated on August 26, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Johannesburg
Discover the top 2 airlines that operate flights from Des Moines to Johannesburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,527 | Average$1,651 | FlexibilityNo cancel fee | On-time68% | |
| Cheapest$1,591 | Average$1,865 | FlexibilityNo cancel fee | On-timeN/A |