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$773+ Cheap flights from Des Moines (DSM) to Johannesburg

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Jan 31 — Feb 71
Sat 1/31
Sat 2/7
1 adult, Economy
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Cheap flight deals from Des Moines to Johannesburg

Best flights from Des Moines to Johannesburg
Discover carefully curated flight deals from Des Moines to Johannesburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 1, 2026.

This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:05 pmDSM - JNB
2 stops28h 55mAmerican Airlines
Tue 5/129:15 pmJNB - DSM
2 stops26h 10mAmerican Airlines
Deal found 12/31$1,237
This Etihad Airways deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:07 amDSM - JNB
2 stops42h 13mMultiple Airlines
Wed 2/189:50 amJNB - DSM
2 stops35h 15mMultiple Airlines
Deal found 12/30$1,343
This British Airways deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:38 pmDSM - JNB
2 stops33h 57mBritish Airways
Mon 3/97:35 pmJNB - DSM
2 stops33h 59mBritish Airways
Deal found 12/29$1,453
This KAYAK deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:59 pmDSM - JNB
2 stops35h 06mEthiopian Air
Tue 5/122:30 pmJNB - DSM
3 stops30h 41mEthiopian Air
Deal found 12/31$1,470
This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/304:25 pmDSM - JNB
2 stops34h 00mAmerican Airlines
Fri 2/67:35 pmJNB - DSM
2 stops33h 29mAmerican Airlines
Deal found 12/31$1,262
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:58 pmDSM - JNB
2 stops28h 02mAmerican Airlines
Sun 7/129:15 pmJNB - DSM
2 stops29h 13mAmerican Airlines
Deal found 12/30$1,362
This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/31:38 pmDSM - JNB
2 stops34h 22mAmerican Airlines
Tue 4/219:15 pmJNB - DSM
2 stops29h 16mAmerican Airlines
Deal found 12/31$1,362
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:26 pmDSM - JNB
2 stops32h 09mAmerican Airlines
Fri 2/207:35 pmJNB - DSM
2 stops30h 44mAmerican Airlines
Deal found 12/29$1,437
This American Airlines deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/151:38 pmDSM - JNB
2 stops36h 47mAmerican Airlines
Sun 2/2210:00 pmJNB - DSM
2 stops32h 19mAmerican Airlines
Deal found 1/1$1,487

Find flight deals from Des Moines to Johannesburg

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Johannesburg (ZA1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 1, 2026.

Round-trip from

$1,237
(American Airlines)

One-way from

$773
(lol.travel)

Popular in

June

Cheapest in

November

Average price

$1,752
From Des Moines to Johannesburg
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One-way flight from Des Moines to Johannesburg
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Highest demand for flights based on searches. 5% potential increase in price ($102 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Johannesburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 1, 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg that are best for you.

Fly from

Des Moines

Fly to

Johannesburg

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 4/25

7:05 pm-7:00 am

2 stops28h 55m

Johannesburg OR Tambo

Tue 5/12

9:15 pm-4:25 pm

2 stops26h 10m

$1,237

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 1/30

4:25 pm-10:25 am

2 stops34h 00m

Johannesburg OR Tambo

Fri 2/6

7:35 pm-9:04 pm

2 stops33h 29m

$1,262

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 2/11

6:07 am-8:20 am

2 stops42h 13m

Johannesburg OR Tambo

Wed 2/18

9:50 am-1:05 pm

2 stops35h 15m

$1,343

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 6/21

7:58 pm-7:00 am

2 stops28h 02m

Johannesburg OR Tambo

Sun 7/12

9:15 pm-7:28 pm

2 stops29h 13m

$1,362

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 4/3

1:38 pm-7:00 am

2 stops34h 22m

Johannesburg OR Tambo

Tue 4/21

9:15 pm-7:31 pm

2 stops29h 16m

$1,362

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 2/13

3:26 pm-7:35 am

2 stops32h 09m

Johannesburg OR Tambo

Fri 2/20

7:35 pm-6:19 pm

2 stops30h 44m

$1,437

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 3/5

1:38 pm-7:35 am

2 stops33h 57m

Johannesburg OR Tambo

Mon 3/9

7:35 pm-10:34 pm

2 stops33h 59m

$1,453

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 4/25

6:59 pm-1:05 pm

2 stops35h 06m

Johannesburg OR Tambo

Tue 5/12

2:30 pm-2:11 pm

3 stops30h 41m

$1,470

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 2/15

1:38 pm-10:25 am

2 stops36h 47m

Johannesburg OR Tambo

Sun 2/22

10:00 pm-10:19 pm

2 stops32h 19m

$1,487

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 3/10

7:00 am-8:40 am

2 stops42h 40m

$773

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 17 results
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Best time to book a flight from Des Moines to Johannesburg

Have a flexible travel schedule? Discover the best time to fly to Johannesburg from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Johannesburg
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Johannesburg

Get insights into the airlines that provide service to Johannesburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Johannesburg. Reviews last updated January 1, 2026.
Get a feel of what it's like to fly with Delta from Des Moines to Johannesburg by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,013 reviews
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Johannesburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Johannesburg?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Johannesburg. 1 airline have flights from Des Moines to Johannesburg on a regular basis. Booking flights from Des Moines to Johannesburg should not be difficult; the airport handles an average of 0 outbound flights to Johannesburg per day.

  • How long is the flight from Des Moines to Johannesburg?

    Airlines like American Airlines fly from Des Moines to Johannesburg in about 28h 55m. The time it takes to get you to your destination can typically vary by up to . There are 8998 mi between Des Moines and Johannesburg.

  • What is the cheapest airline to fly from Des Moines to Johannesburg round-trip?

    Delta, at $1,410, was found to be the cheapest airline from Des Moines to Johannesburg.. Delta is currently priced 16% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Johannesburg that include hotel bookings?

    Yes. In addition to deals on Des Moines to Johannesburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Johannesburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Johannesburg.

  • Can I find deals for business class flights from Des Moines to Johannesburg?

    Yes. Cheapflights offers flight deals from Des Moines to Johannesburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Des Moines to Johannesburg

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to OR Tambo flights
Omaha to OR Tambo flights
Omaha to Cape Town flights
Moline to OR Tambo flights

Top airline flying from Des Moines to Johannesburg

Discover the top airline that operate flights from Des Moines to Johannesburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$1,410Average$1,973FlexibilityNo cancel feeOn-timeN/A

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