$771+ Cheap flights from Des Moines (DSM) to Johannesburg
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Sep 11 — Sep 181
Round-trip
1 adult, Economy
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Best
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One-way
Cheapest flights from Des Moines to JohannesburgExplore the most affordable flight options available from Des Moines to Johannesburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
Explore the most affordable flight options available from Des Moines to Johannesburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
This Etihad Airways deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:05 am -
2 stops42h 10m
Wed 9/169:45 am -
2 stops45h 19m
Deal found 8/11![Multiple Airlines logo]()
$1,316
This Bravofly deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:05 am -
2 stops37h 55m
Fri 10/22:05 pm -
2 stops36h 16m
Deal found 8/10![Qatar Airways logo]()
$1,445
This Cathay Pacific deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:05 am -
2 stops41h 50m
Sun 9/2011:10 am -
2 stops38h 16m
Deal found 8/11![Multiple Airlines logo]()
$1,447
This Bravofly deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
2 stops30h 31m
Wed 9/308:55 pm -
2 stops34h 09m
Deal found 8/9![Qatar Airways logo]()
$1,461
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:29 pm -
2 stops30h 31m
Sun 9/202:05 pm -
2 stops40h 59m
Deal found 8/7![Qatar Airways logo]()
$1,520
This Qatar Airways deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
2 stops30h 31m
Wed 9/308:55 pm -
2 stops34h 09m
Deal found 8/9![Multiple Airlines logo]()
$1,545
This Cathay Pacific deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:05 am -
2 stops41h 40m
Sat 10/311:10 am -
2 stops38h 16m
Deal found 8/11![Multiple Airlines logo]()
$1,550
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:44 pm -
2 stops30h 16m
Thu 10/12:05 pm -
2 stops40h 07m
Deal found 8/10![Qatar Airways logo]()
$1,578
Best flights from Des Moines to JohannesburgDiscover carefully curated flight deals from Des Moines to Johannesburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
Discover carefully curated flight deals from Des Moines to Johannesburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
This FlightHub deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:29 pm -
2 stops30h 31m
Sun 9/202:05 pm -
2 stops40h 59m
Deal found 8/8![Qatar Airways logo]()
$1,520
This Qatar Airways deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
2 stops30h 31m
Wed 9/308:55 pm -
2 stops34h 09m
Deal found 8/9![Multiple Airlines logo]()
$1,545
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:22 pm -
2 stops45h 48m
Sun 9/202:30 pm -
3 stops37h 58m
Deal found 8/10![Ethiopian Air logo]()
$1,684
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:31 am -
1 stop25h 09m
Sat 10/311:15 pm -
2 stops28h 31m
Deal found 8/11![Delta logo]()
$1,856
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 am -
1 stop30h 55m
Thu 10/19:55 pm -
1 stop31h 31m
Deal found 8/10![Virgin Atlantic logo]()
$1,858
This Cathay Pacific deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:05 am -
2 stops41h 40m
Sat 10/311:10 am -
2 stops38h 16m
Deal found 8/11![Multiple Airlines logo]()
$1,550
This Qatar Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:01 pm -
2 stops35h 39m
Wed 11/41:45 pm -
2 stops37h 09m
Deal found 8/10![Qatar Airways logo]()
$1,586
Last-minute flights from Des Moines to JohannesburgDiscover last-minute flight deals from Des Moines to Johannesburg. Data last updated August 12, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Johannesburg. Data last updated August 12, 2026 and is based on user searches.
This Etihad Airways deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:05 am -
2 stops42h 10m
Wed 9/169:45 am -
2 stops45h 19m
Deal found 8/11![Multiple Airlines logo]()
$1,316
This Cathay Pacific deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:05 am -
2 stops41h 50m
Sun 9/2011:10 am -
2 stops38h 16m
Deal found 8/11![Multiple Airlines logo]()
$1,447
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:29 pm -
2 stops30h 31m
Sun 9/202:05 pm -
2 stops40h 59m
Deal found 8/7![Qatar Airways logo]()
$1,520
This Bravofly deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
2 stops30h 31m
Wed 9/308:55 pm -
2 stops34h 09m
Deal found 8/9![Qatar Airways logo]()
$1,461
This Qatar Airways deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
2 stops30h 31m
Wed 9/308:55 pm -
2 stops34h 09m
Deal found 8/9![Multiple Airlines logo]()
$1,545
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:44 pm -
2 stops30h 16m
Thu 10/12:05 pm -
2 stops40h 07m
Deal found 8/10![Qatar Airways logo]()
$1,578
This Bravofly deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:05 am -
2 stops37h 55m
Fri 10/22:05 pm -
2 stops36h 16m
Deal found 8/10![Qatar Airways logo]()
$1,445
This Cathay Pacific deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:05 am -
2 stops41h 40m
Sat 10/311:10 am -
2 stops38h 16m
Deal found 8/11![Multiple Airlines logo]()
$1,550
One-way flights from Des Moines to JohannesburgSearch for one-way flight options from Des Moines to Johannesburg. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
Search for one-way flight options from Des Moines to Johannesburg. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
This Cathay Pacific deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:05 am -
2 stops41h 40m
Deal found 8/11![Multiple Airlines logo]()
$771
This Goibibo deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Goibibo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:35 am -
2 stops39h 35m
Deal found 8/8![Qatar Airways logo]()
$1,024
This Goibibo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Goibibo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
2 stops35h 41m
Deal found 8/10![Qatar Airways logo]()
$1,071
This Goibibo deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Goibibo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:31 am -
1 stop25h 09m
Deal found 8/8![Virgin Atlantic logo]()
$1,180
This Goibibo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Goibibo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:31 am -
1 stop25h 09m
Deal found 8/10![Virgin Atlantic logo]()
$1,191
This Virgin Atlantic deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:31 am -
1 stop25h 09m
Deal found 8/11![Virgin Atlantic logo]()
$1,237
This Air Canada deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:23 pm -
3 stops36h 12m
Deal found 8/8![Air Canada logo]()
$1,297
This Air Canada deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:24 pm -
3 stops36h 11m
Deal found 8/10![Air Canada logo]()
$1,461
Find flight deals from Des Moines to Johannesburg
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Johannesburg (ZA1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 12, 2026.
Round-trip from | $1,316 (Etihad Airways) |
|---|---|
One-way from | $771 (Cathay Pacific) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Johannesburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Fri 9/11
2:29 pm-4:00 am
2 stops30h 31m
Johannesburg OR Tambo
Sun 9/20
2:05 pm-12:04 am
2 stops40h 59m
$1,520
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Wed 9/23
2:29 pm-4:00 am
2 stops30h 31m
Johannesburg OR Tambo
Wed 9/30
8:55 pm-12:04 am
2 stops34h 09m
$1,545
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sat 9/26
7:05 am-7:45 am
2 stops41h 40m
Johannesburg OR Tambo
Sat 10/3
11:10 am-6:26 pm
2 stops38h 16m
$1,550
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sat 10/31
2:01 pm-8:40 am
2 stops35h 39m
Johannesburg OR Tambo
Wed 11/4
1:45 pm-6:54 pm
2 stops37h 09m
$1,586
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Fri 9/11
3:22 pm-8:10 pm
2 stops45h 48m
Johannesburg OR Tambo
Sun 9/20
2:30 pm-9:28 pm
3 stops37h 58m
$1,684
Quickest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sat 9/26
11:31 am-7:40 pm
1 stop25h 09m
Johannesburg OR Tambo
Sat 10/3
11:15 pm-8:46 pm
2 stops28h 31m
$1,856
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 9/24
5:45 am-7:40 pm
1 stop30h 55m
Johannesburg OR Tambo
Thu 10/1
9:55 pm-10:26 pm
1 stop31h 31m
$1,858
Cheapest one-way
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sat 9/26
7:05 am-7:45 am
2 stops41h 40m
$771
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Wed 9/23
10:35 am-9:10 am
2 stops39h 35m
$1,024
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Fri 9/25
2:29 pm-9:10 am
2 stops35h 41m
$1,071
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Johannesburg
Have a flexible travel schedule? Discover the best time to fly to Johannesburg from Des Moines with our price prediction graph.
DSM-ZA1
DSM-JNB
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Johannesburg
DSM-ZA1
DSM-JNB
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Johannesburg
Get insights into the airlines that provide service to Johannesburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Johannesburg. Reviews last updated August 12, 2026.
Get a feel of what it's like to fly with Delta and Qatar Airways from Des Moines to Johannesburg by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Johannesburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Des Moines and Johannesburg flights
Browse other Des Moines and Johannesburg flight options. Last updated on August 12, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on August 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Johannesburg
Discover the top 2 airlines that operate flights from Des Moines to Johannesburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,527 | Average$1,651 | FlexibilityNo cancel fee | On-time68% | |
| Cheapest$1,591 | Average$2,265 | FlexibilityNo cancel fee | On-timeN/A |