$704+ Cheap flights from Des Moines (DSM) to South Africa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to South Africa
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Best
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One-way
Cheapest flights from Des Moines to South AfricaExplore the most affordable flight options available from Des Moines to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Des Moines to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:26 am -
2 stops39h 29m
Wed 10/2111:10 am -
2 stops44h 04m
Deal found 8/30![Multiple Airlines logo]()
$1,383
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:26 am -
2 stops39h 29m
Tue 10/2011:10 am -
2 stops44h 04m
Deal found 8/28![Multiple Airlines logo]()
$1,389
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops44h 04m
Deal found 8/30![Multiple Airlines logo]()
$1,392
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops42h 57m
Deal found 8/31![Multiple Airlines logo]()
$1,397
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:26 am -
2 stops39h 29m
Thu 10/2211:10 am -
2 stops42h 57m
Deal found 8/31![Multiple Airlines logo]()
$1,433
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Mon 9/2111:10 am -
2 stops43h 54m
Deal found 8/31![Multiple Airlines logo]()
$1,440
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Sun 9/2011:10 am -
2 stops43h 54m
Deal found 8/28![Multiple Airlines logo]()
$1,447
Best flights from Des Moines to South AfricaDiscover carefully curated flight deals from Des Moines to South Africa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Des Moines to South Africa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:26 am -
2 stops39h 29m
Wed 10/2111:10 am -
2 stops44h 04m
Deal found 8/30![Multiple Airlines logo]()
$1,389
This Qatar Airways deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:26 am -
2 stops35h 34m
Mon 10/192:05 pm -
2 stops35h 55m
Deal found 9/1![Qatar Airways logo]()
$1,643
This oojo deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
2 stops31h 10m
Mon 10/2611:00 pm -
3 stops49h 27m
Deal found 8/28![Ethiopian Air logo]()
$1,701
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:26 am -
2 stops39h 29m
Tue 10/2011:10 am -
2 stops44h 04m
Deal found 8/28![Multiple Airlines logo]()
$1,389
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops44h 04m
Deal found 8/28![Multiple Airlines logo]()
$1,397
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:29 am -
2 stops41h 26m
Mon 10/2611:00 am -
2 stops39h 00m
Deal found 8/28![Multiple Airlines logo]()
$1,397
This Cathay Pacific deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops42h 57m
Deal found 9/1![Multiple Airlines logo]()
$1,397
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:26 am -
2 stops39h 29m
Thu 10/2211:10 am -
2 stops42h 57m
Deal found 8/31![Multiple Airlines logo]()
$1,433
This Etihad Airways deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:29 am -
2 stops41h 51m
Sat 10/249:45 am -
2 stops45h 29m
Deal found 9/2![Multiple Airlines logo]()
$1,457
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/275:30 am -
2 stops41h 55m
Tue 1/1911:00 am -
2 stops40h 03m
Deal found 8/31![Multiple Airlines logo]()
$1,576
Last-minute flights from Des Moines to South AfricaDiscover last-minute flight deals from Des Moines to South Africa. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to South Africa. Data last updated September 2, 2026 and is based on user searches.
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Mon 9/2111:10 am -
2 stops43h 54m
Deal found 8/31![Multiple Airlines logo]()
$1,440
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am -
2 stops38h 20m
Sun 9/2011:10 am -
2 stops43h 54m
Deal found 8/28![Multiple Airlines logo]()
$1,447
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops42h 57m
Deal found 8/31![Multiple Airlines logo]()
$1,397
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:26 am -
2 stops39h 19m
Mon 10/1911:10 am -
2 stops44h 04m
Deal found 8/30![Multiple Airlines logo]()
$1,392
This Cathay Pacific deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:26 am -
2 stops39h 29m
Tue 10/2011:10 am -
2 stops44h 04m
Deal found 8/28![Multiple Airlines logo]()
$1,389
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Wed 10/149:26 am -
2 stops39h 29m
Wed 10/2111:10 am -
2 stops44h 04m
Deal found 8/30![Multiple Airlines logo]()
$1,383
This Cathay Pacific deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:26 am -
2 stops39h 29m
Thu 10/2211:10 am -
2 stops42h 57m
Deal found 8/31![Multiple Airlines logo]()
$1,433
One-way flights from Des Moines to South AfricaSearch for one-way flight options from Des Moines to South Africa. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Des Moines to South Africa. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Cathay Pacific deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/237:29 am -
2 stops39h 56m
Deal found 8/30![Multiple Airlines logo]()
$704
This Goibibo deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Goibibo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:01 pm -
2 stops36h 09m
Deal found 9/1![Qatar Airways logo]()
$1,171
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/235:45 am -
1 stop29h 25m
Deal found 8/30![Delta logo]()
$1,190
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:27 am -
1 stop25h 13m
Deal found 9/1![Delta logo]()
$1,204
This Flightnetwork deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:55 pm -
3 stops30h 40m
Deal found 9/1![Lufthansa logo]()
$1,309
Find flight deals from Des Moines to South Africa
Keep the following information in mind while searching for Des Moines to South Africa flight deals. Data was last updated September 2, 2026.
Round-trip from | $1,377 (Etihad Airways) |
|---|---|
One-way from | $704 (Cathay Pacific) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Des Moines to South Africa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Wed 10/14
9:26 am-7:55 am
2 stops39h 29m
Johannesburg OR Tambo
Wed 10/21
11:10 am-12:14 am
2 stops44h 04m
$1,389
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Tue 10/13
9:26 am-7:55 am
2 stops39h 29m
Johannesburg OR Tambo
Tue 10/20
11:10 am-12:14 am
2 stops44h 04m
$1,389
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Mon 10/12
9:26 am-7:45 am
2 stops39h 19m
Johannesburg OR Tambo
Mon 10/19
11:10 am-12:14 am
2 stops44h 04m
$1,397
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 10/22
7:29 am-7:55 am
2 stops41h 26m
Johannesburg OR Tambo
Mon 10/26
11:00 am-7:00 pm
2 stops39h 00m
$1,397
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Mon 10/5
9:26 am-7:45 am
2 stops39h 19m
Johannesburg OR Tambo
Mon 10/19
11:10 am-11:07 pm
2 stops42h 57m
$1,397
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 10/15
9:26 am-7:55 am
2 stops39h 29m
Johannesburg OR Tambo
Thu 10/22
11:10 am-11:07 pm
2 stops42h 57m
$1,433
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sat 10/17
7:29 am-8:20 am
2 stops41h 51m
Johannesburg OR Tambo
Sat 10/24
9:45 am-12:14 am
2 stops45h 29m
$1,457
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sun 12/27
5:30 am-7:25 am
2 stops41h 55m
Johannesburg OR Tambo
Tue 1/19
11:00 am-7:03 pm
2 stops40h 03m
$1,576
Quickest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 10/15
9:26 am-4:00 am
2 stops35h 34m
Johannesburg OR Tambo
Mon 10/19
2:05 pm-7:00 pm
2 stops35h 55m
$1,643
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 10/22
6:00 am-8:10 pm
2 stops31h 10m
Johannesburg OR Tambo
Mon 10/26
11:00 pm-5:27 pm
3 stops49h 27m
$1,701
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Des Moines to South Africa
Have a flexible travel schedule? Discover the best time to fly to South Africa from Des Moines with our price prediction graph.
DSM-JNB
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to South Africa
DSM-ZA0
DSM-JNB
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Africa
Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated September 2, 2026.
See what other customers who have flown with Delta and Qatar Airways from Des Moines to South Africa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
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Complete your trip
Complete your trip to South Africa by adding a car rental and/or hotel reservation to your travel itinerary.
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Des Moines and South Africa flights
Browse other Des Moines and South Africa flight options. Last updated on September 2, 2026.
Popular flight searches
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Top 2 airlines flying from Des Moines to South Africa
Discover the top 2 airlines that operate flights from Des Moines to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,527 | Average$1,651 | FlexibilityNo cancel fee | On-time68% | |
| Cheapest$1,591 | Average$1,865 | FlexibilityNo cancel fee | On-timeN/A |