$743+ Cheap flights from Des Moines (DSM) to South Africa
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JNB
Oct 26 — Nov 21
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to South Africa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to South Africa
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Best
Last-minute
One-way
Cheapest flights from Des Moines to South AfricaExplore the most affordable flight options available from Des Moines to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
Explore the most affordable flight options available from Des Moines to South Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
This lastminute.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:25 am -
2 stops39h 15m
Sun 11/151:45 pm -
2 stops37h 11m
Deal found 9/23![Qatar Airways logo]()
$1,508
This Cathay Pacific deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:23 am -
2 stops40h 02m
Fri 11/1311:00 am -
2 stops44h 30m
Deal found 9/22![Multiple Airlines logo]()
$1,548
This Cathay Pacific deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:25 am -
2 stops38h 00m
Sat 11/1411:00 am -
2 stops39h 56m
Deal found 9/23![Multiple Airlines logo]()
$1,551
This Cathay Pacific deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/275:30 am -
2 stops41h 55m
Tue 1/1911:00 am -
2 stops40h 13m
Deal found 9/24![Multiple Airlines logo]()
$1,654
This oojo deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:31 pm -
2 stops41h 54m
Mon 11/1612:35 pm -
2 stops43h 43m
Deal found 9/24![Qatar Airways logo]()
$1,715
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:43 pm -
1 stop40h 27m
Tue 1/199:20 pm -
1 stop20h 58m
Deal found 9/22![Delta logo]()
$1,821
This Ovago deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am -
2 stops24h 30m
Wed 9/302:30 pm -
3 stops30h 45m
Deal found 9/24![Ethiopian Air logo]()
$1,830
This Bravofly deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/83:03 pm -
2 stops23h 22m
Sun 11/159:20 pm -
1 stop33h 15m
Deal found 9/24![Multiple Airlines logo]()
$1,845
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:07 pm -
1 stop19h 03m
Sat 11/149:20 pm -
1 stop21h 24m
Deal found 9/23![Delta logo]()
$1,866
This SmartFares deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:45 pm -
2 stops28h 55m
Sat 11/149:30 am -
2 stops44h 25m
Deal found 9/23![Lufthansa logo]()
$1,962
This SmartFares deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
2 stops28h 55m
Fri 11/139:30 am -
2 stops44h 25m
Deal found 9/22![Lufthansa logo]()
$1,968
This Virgin Atlantic deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:59 pm -
1 stop19h 36m
Mon 11/168:50 pm -
1 stop29h 17m
Deal found 9/24![Virgin Atlantic logo]()
$2,038
Best flights from Des Moines to South AfricaDiscover carefully curated flight deals from Des Moines to South Africa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
Discover carefully curated flight deals from Des Moines to South Africa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
This Bravofly deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:25 am -
2 stops39h 15m
Sun 11/151:45 pm -
2 stops37h 11m
Deal found 9/24![Qatar Airways logo]()
$1,516
This Cathay Pacific deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:23 am -
2 stops40h 02m
Fri 11/1311:00 am -
2 stops44h 30m
Deal found 9/22![Multiple Airlines logo]()
$1,548
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:43 pm -
1 stop40h 27m
Tue 1/199:20 pm -
2 stops27h 30m
Deal found 9/21![Delta logo]()
$1,826
This Virgin Atlantic deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:59 pm -
1 stop19h 36m
Mon 11/168:50 pm -
1 stop29h 17m
Deal found 9/24![Virgin Atlantic logo]()
$2,038
This Qatar Airways deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/282:39 pm -
2 stops34h 01m
Mon 2/11:45 pm -
2 stops37h 28m
Deal found 9/22![Qatar Airways logo]()
$1,546
This Cathay Pacific deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/279:53 am -
2 stops37h 32m
Tue 1/1911:00 am -
2 stops40h 13m
Deal found 9/21![Multiple Airlines logo]()
$1,654
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:59 pm -
1 stop19h 36m
Mon 11/168:50 pm -
2 stops30h 25m
Deal found 9/24![Delta logo]()
$2,062
This Bravofly deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:07 pm -
2 stops35h 33m
Fri 11/138:50 pm -
1 stop33h 45m
Deal found 9/22![Multiple Airlines logo]()
$2,148
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:27 am -
1 stop23h 08m
Fri 11/1312:30 am -
2 stops42h 14m
Deal found 9/23![Delta logo]()
$2,174
This AranGrant deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AranGrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:42 pm -
2 stops28h 58m
Fri 1/17:10 pm -
2 stops30h 30m
Deal found 9/21![Lufthansa logo]()
$6,649
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/172:58 pm -
1 stop19h 37m
Fri 1/18:50 pm -
1 stop21h 59m
Deal found 9/21![Delta logo]()
$10,421
Last-minute flights from Des Moines to South AfricaDiscover last-minute flight deals from Des Moines to South Africa. Data last updated September 26, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to South Africa. Data last updated September 26, 2026 and is based on user searches.
This Ovago deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am -
2 stops24h 30m
Wed 9/302:30 pm -
3 stops30h 45m
Deal found 9/24![Ethiopian Air logo]()
$1,830
This Justfly.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:05 am -
2 stops43h 05m
Wed 9/308:55 pm -
2 stops34h 09m
Deal found 9/24![Qatar Airways logo]()
$1,943
This Virgin Atlantic deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:34 pm -
1 stop22h 06m
Wed 9/309:55 pm -
1 stop27h 14m
Deal found 9/24![Virgin Atlantic logo]()
$2,761
This Air Canada deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:24 pm -
3 stops36h 11m
Wed 9/307:20 pm -
3 stops35h 15m
Deal found 9/24![Air Canada logo]()
$8,624
One-way flights from Des Moines to South AfricaSearch for one-way flight options from Des Moines to South Africa. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
Search for one-way flight options from Des Moines to South Africa. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
This Cathay Pacific deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:26 am -
2 stops38h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$743
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:25 pm -
3 stops41h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$968
This Cathay Pacific deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cathay Pacific is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/139:26 am -
3 stops47h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$1,142
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:27 am -
1 stop24h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Delta logo]()
$1,204
This Ovago deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/138:00 am -
2 stops42h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![SWISS logo]()
$1,228
This Expedia deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/152:59 pm -
1 stop19h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Virgin Atlantic logo]()
$1,271
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1311:04 am -
1 stop23h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Delta logo]()
$1,593
Find flight deals from Des Moines to South Africa
Keep the following information in mind while searching for Des Moines to South Africa flight deals. Data was last updated September 26, 2026.
Round-trip from | $1,508 (lastminute.com) |
|---|---|
One-way from | $743 (Cathay Pacific) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 26, 2026.
Use the filters below to find and compare flights from Des Moines to South Africa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Tue 10/27
9:26 am-7:25 am
2 stops38h 59m
Johannesburg OR Tambo
Wed 12/31
12:00 am-4:00 pm
Nonstop0h 00m
$743
Des MoinesCape Town
DSM Des Moines - CPT Cape Town Intl
DSMCPT
Des Moines
Sun 11/15
12:25 pm-2:10 pm
3 stops41h 45m
Cape Town Intl
Wed 12/31
12:00 am-4:00 pm
Nonstop0h 00m
$968
Des MoinesCape Town
DSM Des Moines - CPT Cape Town Intl
DSMCPT
Des Moines
Sat 3/13
9:26 am-4:45 pm
3 stops47h 19m
Cape Town Intl
Wed 12/31
12:00 am-4:00 pm
Nonstop0h 00m
$1,142
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Tue 10/27
11:27 am-7:10 pm
1 stop24h 43m
Johannesburg OR Tambo
Wed 12/31
12:00 am-4:00 pm
Nonstop0h 00m
$1,204
Des MoinesCape Town
DSM Des Moines - CPT Cape Town Intl
DSMCPT
Des Moines
Sat 3/13
8:00 am-10:40 am
2 stops42h 40m
Cape Town Intl
Wed 12/31
12:00 am-4:00 pm
Nonstop0h 00m
$1,228
Quickest round-trip
Des MoinesCape Town
DSM Des Moines - CPT Cape Town Intl
DSMCPT
Des Moines
Sun 11/15
2:59 pm-6:35 pm
1 stop19h 36m
Cape Town Intl
Wed 12/31
12:00 am-4:00 pm
Nonstop0h 00m
$1,271
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Sun 11/8
9:25 am-8:40 am
2 stops39h 15m
Johannesburg OR Tambo
Sun 11/15
1:45 pm-6:56 pm
2 stops37h 11m
$1,516
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Thu 1/28
2:39 pm-8:40 am
2 stops34h 01m
Johannesburg OR Tambo
Mon 2/1
1:45 pm-7:13 pm
2 stops37h 28m
$1,546
Des MoinesJohannesburg
DSM Des Moines - JNB Johannesburg OR Tambo
DSMJNB
Des Moines
Fri 11/6
7:23 am-7:25 am
2 stops40h 02m
Johannesburg OR Tambo
Fri 11/13
11:00 am-11:30 pm
2 stops44h 30m
$1,548
Des MoinesCape Town
DSM Des Moines - CPT Cape Town Intl
DSMCPT
Des Moines
Sat 3/13
11:04 am-6:35 pm
1 stop23h 31m
Cape Town Intl
Wed 12/31
12:00 am-4:00 pm
Nonstop0h 00m
$1,593
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Des Moines to South Africa
Have a flexible travel schedule? Discover the best time to fly to South Africa from Des Moines with our price prediction graph.
DSM-JNB
DSM-CPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to South Africa
DSM-ZA0
DSM-JNB
DSM-CPT
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Africa
Get insights into the airlines that provide service to South Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Africa. Reviews last updated September 26, 2026.
See what other customers who have flown with Delta and Qatar Airways from Des Moines to South Africa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to South Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and South Africa flights
Browse other Des Moines and South Africa flight options. Last updated on September 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to South Africa
Discover the top 2 airlines that operate flights from Des Moines to South Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,527 | Average$1,651 | FlexibilityNo cancel fee | On-time68% | |
| Cheapest$1,591 | Average$2,038 | FlexibilityNo cancel fee | On-timeN/A |