$523+ Cheap flights from Panama City (PTY) to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
Apr 6 — Apr 131
Round-trip
1 adult, Economy
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Cheapest flights from Panama City to ItalyExplore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 7, 2026.
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 7, 2026.
This Air France deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:55 pm
PTY
- MXP
1 stop27h 20m
Air France
Mon 6/86:45 am
MXP
- PTY
1 stop20h 00m
Air France
Deal found 3/7![Air France logo]()
$680
This Booking.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:20 pm
PTY
- FCO
1 stop32h 45m
Turkish Airlines
Mon 4/277:05 am
FCO
- PTY
1 stop20h 20m
Turkish Airlines
Deal found 3/6![Turkish Airlines logo]()
$698
This Turkish Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:20 pm
PTY
- MXP
1 stop18h 25m
Turkish Airlines
Wed 4/296:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 3/6![Turkish Airlines logo]()
$703
This Turkish Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:20 pm
PTY
- MXP
1 stop36h 40m
Turkish Airlines
Mon 9/216:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 3/5![Turkish Airlines logo]()
$706
This Turkish Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:20 pm
PTY
- FCO
1 stop32h 45m
Turkish Airlines
Mon 6/17:05 am
FCO
- PTY
1 stop20h 20m
Turkish Airlines
Deal found 3/2![Turkish Airlines logo]()
$709
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:10 pm
PTY
- MXP
1 stop27h 05m
Air France
Sun 5/176:45 am
MXP
- PTY
1 stop20h 00m
Air France
Deal found 3/4![Air France logo]()
$724
This Air France deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:10 pm
PTY
- MXP
1 stop27h 05m
Air France
Mon 5/189:15 am
MXP
- PTY
1 stop17h 30m
Air France
Deal found 3/7![Air France logo]()
$725
This CheapOair deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:20 pm
PTY
- VCE
1 stop27h 00m
Turkish Airlines
Wed 4/299:55 am
VCE
- PTY
1 stop17h 30m
Turkish Airlines
Deal found 3/3![Turkish Airlines logo]()
$730
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:27 pm
PTY
- FCO
1 stop37h 23m
Air France
Sun 5/246:05 am
FCO
- PTY
1 stop20h 40m
Air France
Deal found 3/4![Air France logo]()
$736
This Air France deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:27 pm
PTY
- FCO
1 stop37h 23m
Multiple Airlines
Sun 5/245:25 pm
FCO
- PTY
1 stop30h 25m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$737
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
PTY
- VCE
1 stop33h 05m
Multiple Airlines
Tue 4/2812:45 pm
VCE
- PTY
1 stop14h 00m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$741
This Turkish Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:20 pm
PTY
- FCO
1 stop18h 15m
Turkish Airlines
Fri 5/87:05 am
FCO
- PTY
2 stops42h 25m
Turkish Airlines
Deal found 3/5![Turkish Airlines logo]()
$742
Best flights from Panama City to ItalyDiscover carefully curated flight deals from Panama City to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 7, 2026.
Discover carefully curated flight deals from Panama City to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 7, 2026.
This Turkish Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:20 pm
PTY
- MXP
1 stop18h 25m
Turkish Airlines
Wed 4/296:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 3/6![Turkish Airlines logo]()
$703
This Air Europa deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:25 pm
PTY
- VCE
1 stop30h 30m
Air Europa
Thu 5/2810:45 am
VCE
- PTY
1 stop14h 55m
Air Europa
Deal found 3/4![Air Europa logo]()
$750
This KLM deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
PTY
- VCE
1 stop33h 05m
Multiple Airlines
Sun 4/1912:45 pm
VCE
- PTY
1 stop14h 00m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$765
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:50 pm
PTY
- FCO
1 stop20h 55m
KLM
Mon 5/257:45 pm
FCO
- PTY
1 stop28h 05m
KLM
Deal found 3/4![KLM logo]()
$768
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:00 am
PTY
- FCO
2 stops39h 15m
United Airlines
Tue 9/1510:20 am
FCO
- PTY
2 stops40h 11m
United Airlines
Deal found 3/6![United Airlines logo]()
$918
This Air Europa deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:25 pm
PTY
- MXP
1 stop30h 20m
Air Europa
Sun 5/316:15 pm
MXP
- PTY
1 stop31h 25m
Air Europa
Deal found 3/3![Air Europa logo]()
$760
This Turkish Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:20 pm
PTY
- MXP
1 stop27h 20m
Turkish Airlines
Fri 5/153:15 pm
MXP
- PTY
1 stop36h 10m
Turkish Airlines
Deal found 3/5![Turkish Airlines logo]()
$798
This KLM deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:50 pm
PTY
- LIN
1 stop21h 00m
Multiple Airlines
Thu 6/186:25 am
LIN
- PTY
1 stop20h 20m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$799
This Air Europa deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:25 pm
PTY
- VCE
1 stop14h 10m
Air Europa
Sun 6/2110:45 am
VCE
- PTY
1 stop14h 55m
Air Europa
Deal found 3/5![Air Europa logo]()
$768
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
PTY
- FCO
1 stop31h 45m
KLM
Thu 4/236:30 am
FCO
- PTY
2 stops20h 15m
KLM
Deal found 3/4![KLM logo]()
$864
This Turkish Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:20 pm
PTY
- VCE
1 stop27h 00m
Turkish Airlines
Mon 4/279:20 am
VCE
- PTY
1 stop18h 05m
Turkish Airlines
Deal found 3/3![Turkish Airlines logo]()
$804
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:50 pm
PTY
- NAP
1 stop20h 05m
Multiple Airlines
Sun 6/147:15 pm
NAP
- PTY
1 stop31h 30m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$825
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:55 pm
PTY
- FCO
2 stops26h 00m
United Airlines
Sat 5/99:45 am
FCO
- PTY
2 stops25h 19m
United Airlines
Deal found 3/6![United Airlines logo]()
$918
This Air Europa deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:25 pm
PTY
- MXP
1 stop13h 50m
Air Europa
Fri 5/2911:05 am
MXP
- PTY
1 stop14h 35m
Air Europa
Deal found 3/4![Air Europa logo]()
$788
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:55 pm
PTY
- TRN
2 stops17h 45m
KLM
Tue 6/236:05 am
TRN
- PTY
2 stops20h 40m
KLM
Deal found 3/3![KLM logo]()
$880
This Turkish Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:20 pm
PTY
- VCE
1 stop31h 45m
Turkish Airlines
Tue 4/288:00 pm
VCE
- PTY
1 stop31h 25m
Turkish Airlines
Deal found 3/2![Turkish Airlines logo]()
$825
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
PTY
- FCO
1 stop31h 45m
Multiple Airlines
Thu 4/2310:00 am
FCO
- PTY
1 stop16h 45m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$832
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:55 pm
PTY
- FCO
2 stops26h 00m
United Airlines
Thu 4/2312:55 pm
FCO
- PTY
2 stops32h 19m
United Airlines
Deal found 3/4![United Airlines logo]()
$919
This Turkish Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:20 pm
PTY
- NAP
1 stop27h 05m
Turkish Airlines
Fri 5/223:45 pm
NAP
- PTY
1 stop35h 40m
Turkish Airlines
Deal found 3/2![Turkish Airlines logo]()
$831
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:50 pm
PTY
- FCO
1 stop31h 45m
Multiple Airlines
Sat 5/308:10 pm
FCO
- PTY
1 stop31h 10m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$841
This Air Europa deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:25 pm
PTY
- MXP
1 stop13h 50m
Air Europa
Sat 5/306:15 pm
MXP
- PTY
1 stop31h 25m
Air Europa
Deal found 3/5![Air Europa logo]()
$842
This KLM deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:50 pm
PTY
- LIN
1 stop32h 15m
KLM
Sun 5/314:50 pm
LIN
- PTY
1 stop31h 00m
KLM
Deal found 3/7![KLM logo]()
$929
This Turkish Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:20 pm
PTY
- MXP
1 stop36h 40m
Turkish Airlines
Mon 9/217:45 pm
MXP
- PTY
2 stops29h 40m
Turkish Airlines
Deal found 3/5![Turkish Airlines logo]()
$853
This British Airways deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:49 pm
PTY
- MXP
2 stops24h 01m
Multiple Airlines
Fri 5/1510:25 am
MXP
- PTY
1 stop16h 35m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$862
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:50 pm
PTY
- NAP
1 stop32h 05m
KLM
Fri 5/2210:45 pm
NAP
- PTY
2 stops28h 00m
KLM
Deal found 3/4![KLM logo]()
$950
This Air Europa deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:25 pm
PTY
- VCE
1 stop14h 10m
Air Europa
Tue 4/2810:45 am
VCE
- PTY
1 stop14h 55m
Air Europa
Deal found 3/2![Air Europa logo]()
$890
This KLM deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:50 pm
PTY
- LIN
1 stop21h 00m
Multiple Airlines
Fri 5/298:45 pm
LIN
- PTY
1 stop30h 00m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$866
This Turkish Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:05 pm
PTY
- VCE
1 stop29h 15m
Turkish Airlines
Mon 4/272:05 pm
VCE
- PTY
2 stops35h 20m
Turkish Airlines
Deal found 3/2![Turkish Airlines logo]()
$884
This Air Europa deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:25 pm
PTY
- FCO
1 stop14h 00m
Air Europa
Sun 6/284:35 pm
FCO
- PTY
1 stop33h 05m
Air Europa
Deal found 3/4![Air Europa logo]()
$892
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:50 pm
PTY
- NAP
1 stop31h 55m
KLM
Sun 5/3112:05 pm
NAP
- PTY
1 stop35h 45m
KLM
Deal found 3/3![KLM logo]()
$1,057
Last-minute flights from Panama City to ItalyDiscover last-minute flight deals from Panama City to Italy. Data last updated March 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Italy. Data last updated March 7, 2026 and is based on user searches.
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
PTY
- VCE
1 stop33h 05m
KLM
Wed 4/296:00 am
VCE
- PTY
1 stop17h 50m
KLM
Deal found 3/3![KLM logo]()
$741
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
PTY
- VCE
1 stop33h 05m
KLM
Sun 4/1911:45 am
VCE
- PTY
1 stop36h 05m
KLM
Deal found 3/4![KLM logo]()
$759
This KLM deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
PTY
- VCE
1 stop33h 05m
Multiple Airlines
Sun 4/1912:45 pm
VCE
- PTY
1 stop14h 00m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$765
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:50 pm
PTY
- VCE
1 stop33h 05m
Multiple Airlines
Wed 4/295:55 am
VCE
- PTY
2 stops17h 55m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$771
This CheapOair deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:20 pm
PTY
- VCE
1 stop27h 00m
Turkish Airlines
Wed 4/299:55 am
VCE
- PTY
1 stop17h 30m
Turkish Airlines
Deal found 3/3![Turkish Airlines logo]()
$730
This Turkish Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:20 pm
PTY
- MXP
1 stop18h 25m
Turkish Airlines
Wed 4/296:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 3/6![Turkish Airlines logo]()
$703
This Booking.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:20 pm
PTY
- FCO
1 stop32h 45m
Turkish Airlines
Mon 4/277:05 am
FCO
- PTY
1 stop20h 20m
Turkish Airlines
Deal found 3/6![Turkish Airlines logo]()
$698
This Turkish Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:20 pm
PTY
- MXP
1 stop36h 40m
Turkish Airlines
Mon 9/216:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 3/5![Turkish Airlines logo]()
$706
This Turkish Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:20 pm
PTY
- FCO
1 stop32h 45m
Turkish Airlines
Mon 6/17:05 am
FCO
- PTY
1 stop20h 20m
Turkish Airlines
Deal found 3/2![Turkish Airlines logo]()
$709
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:27 pm
PTY
- FCO
1 stop37h 23m
Air France
Sun 5/246:05 am
FCO
- PTY
1 stop20h 40m
Air France
Deal found 3/4![Air France logo]()
$736
This Air France deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:27 pm
PTY
- FCO
1 stop37h 23m
Multiple Airlines
Sun 5/245:25 pm
FCO
- PTY
1 stop30h 25m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$737
This Turkish Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:20 pm
PTY
- FCO
1 stop18h 15m
Turkish Airlines
Fri 5/87:05 am
FCO
- PTY
2 stops42h 25m
Turkish Airlines
Deal found 3/5![Turkish Airlines logo]()
$742
One-way flights from Panama City to ItalySearch for one-way flight options from Panama City to Italy. Find affordable one-way fares based on user searches. Data last updated March 7, 2026.
Search for one-way flight options from Panama City to Italy. Find affordable one-way fares based on user searches. Data last updated March 7, 2026.
This Mytrip deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:50 pm
PTY
- MXP
3 stops33h 15m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$523
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:15 pm
PTY
- FCO
2 stops40h 30m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$539
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:25 pm
PTY
- FCO
2 stops40h 05m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$547
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:50 pm
PTY
- LIN
3 stops35h 25m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$574
This Mytrip deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:30 am
PTY
- FCO
3 stops35h 45m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$582
This Trip.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:55 pm
PTY
- MXP
2 stops24h 05m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$589
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:34 am
PTY
- FCO
3 stops32h 51m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$596
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:34 pm
PTY
- FCO
2 stops44h 21m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$606
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1012:23 pm
PTY
- MXP
3 stops29h 22m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$607
This Trip.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:25 pm
PTY
- MXP
1 stop13h 50m
Air Europa
Deal found 3/3![Air Europa logo]()
$634
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:25 pm
PTY
- FCO
1 stop14h 00m
Air Europa
Deal found 3/3![Air Europa logo]()
$637
This SmartFares deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:05 pm
PTY
- FCO
1 stop20h 30m
Turkish Airlines
Deal found 3/2![Turkish Airlines logo]()
$638
Find flight deals from Panama City to Italy
Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated March 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $680 (Air France) |
One-way from | $523 (Mytrip) |
Popular in | January |
Cheapest in | April |
Average price | $854 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 7, 2026.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Wed 4/15
10:20 pm-11:45 pm
1 stop18h 25m
Milan Malpensa
Wed 4/29
6:50 am-8:25 pm
1 stop20h 35m
$703
Panama CityVenice
PTY - VCE
PTYVCE
Panama City Tocumen Intl
Sun 5/24
8:25 pm-9:55 am
1 stop30h 30m
Venice Marco Polo
Thu 5/28
10:45 am-6:40 pm
1 stop14h 55m
$750
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Sat 5/9
8:25 pm-9:45 am
1 stop30h 20m
Milan Malpensa
Sun 5/31
6:15 pm-6:40 pm
1 stop31h 25m
$760
Panama CityVenice
PTY - VCE
PTYVCE
Panama City Tocumen Intl
Mon 4/6
6:50 pm-10:55 am
1 stop33h 05m
Venice Marco Polo
Sun 4/19
12:45 pm-7:45 pm
1 stop14h 00m
$765
Panama CityRome
PTY - FCO
PTYFCO
Panama City Tocumen Intl
Sun 5/10
6:50 pm-10:45 pm
1 stop20h 55m
Rome Fiumicino
Mon 5/25
7:45 pm-4:50 pm
1 stop28h 05m
$768
Panama CityVenice
PTY - VCE
PTYVCE
Panama City Tocumen Intl
Thu 6/11
8:25 pm-5:35 pm
1 stop14h 10m
Venice Marco Polo
Sun 6/21
10:45 am-6:40 pm
1 stop14h 55m
$768
Quickest round-trip
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Mon 5/18
8:25 pm-5:15 pm
1 stop13h 50m
Milan Malpensa
Fri 5/29
11:05 am-6:40 pm
1 stop14h 35m
$788
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Wed 5/6
10:20 pm-8:40 am
1 stop27h 20m
Milan Malpensa
Fri 5/15
3:15 pm-8:25 pm
1 stop36h 10m
$798
Panama CityMilan
PTY - LIN
PTYLIN
Panama City Tocumen Intl
Mon 5/18
6:50 pm-10:50 pm
1 stop21h 00m
Milan Linate
Thu 6/18
6:25 am-7:45 pm
1 stop20h 20m
$799
Panama CityVenice
PTY - VCE
PTYVCE
Panama City Tocumen Intl
Wed 4/15
10:20 pm-8:20 am
1 stop27h 00m
Venice Marco Polo
Mon 4/27
9:20 am-8:25 pm
1 stop18h 05m
$804
Showing 1-10 of 58 resultsSorted by cheapest first
Best time to book a flight from Panama City to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
PTY-MXP
PTY-FCO
PTY-LIN
PTY-VCE
PTY-NAP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Italy
PTY-IT0
PTY-MXP
PTY-FCO
PTY-LIN
PTY-VCE
What is the cheapest month to book a flight from Panama City to Italy?
Currently, June is the cheapest month in which you can book a flight from Panama City to Italy (average of $384). Flying from Panama City to Italy in January is currently the most expensive (average of $773). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Italy
Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated March 7, 2026.
Get a feel of what it's like to fly with Air France, Turkish Airlines, and Iberia from Panama City to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Crew
8.1
Comfort
7.3
Boarding
7.4
Overall
7.4
Food
7.0
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Crew
8.1
Comfort
7.3
Boarding
7.4
Overall
7.4
Food
7.0
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Crew
8.1
Comfort
7.3
Boarding
7.4
Overall
7.4
Food
7.0
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Crew
8.1
Comfort
7.3
Boarding
7.4
Overall
7.4
Food
7.0
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Crew
8.1
Comfort
7.3
Boarding
7.4
Overall
7.4
Food
7.0
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Entertainment
7.0
Crew
8.1
Comfort
7.3
Boarding
7.4
Overall
7.4
Food
7.0
Reviews
1 / 20
6.0
GoodJayesh,Jan 2026
CDG - NMI
Related info for your journey
Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Italy by cabin class
Find flights from Panama City to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Italy flights
Browse other Panama City and Italy flight options. Last updated on March 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 3 airlines flying from Panama City to Italy
Discover the top 3 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$678 | Average$756 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$679 | Average$1,146 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$705 | Average$926 | FlexibilityNo cancel fee | On-time77% |