$549+ Cheap flights from Panama City (PTY) to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
Jul 17 — Jul 241
Round-trip
1 adult, Economy
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Cheapest flights from Panama City to ItalyExplore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.
This KLM deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:50 pm
PTY
- LIN
1 stop21h 00m
Multiple Airlines
Tue 9/226:25 am
LIN
- PTY
1 stop20h 20m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$820
This Booking.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:45 pm
PTY
- VCE
1 stop28h 50m
Turkish Airlines
Fri 11/139:35 am
VCE
- PTY
1 stop40h 30m
Turkish Airlines
Deal found 6/13![Turkish Airlines logo]()
$822
This Booking.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:45 pm
PTY
- FCO
1 stop18h 10m
Turkish Airlines
Thu 11/1211:15 am
FCO
- PTY
1 stop38h 50m
Turkish Airlines
Deal found 6/15![Turkish Airlines logo]()
$837
This Turkish Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:20 pm
PTY
- MXP
1 stop36h 25m
Turkish Airlines
Fri 10/236:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 6/16![Turkish Airlines logo]()
$844
This Air France deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:55 pm
PTY
- MXP
1 stop18h 05m
Air France
Wed 8/266:35 pm
MXP
- PTY
1 stop32h 10m
Air France
Deal found 6/17![Air France logo]()
$845
This Turkish Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:45 pm
PTY
- FCO
1 stop30h 05m
Turkish Airlines
Mon 11/236:40 am
FCO
- PTY
1 stop19h 25m
Turkish Airlines
Deal found 6/16![Turkish Airlines logo]()
$854
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:50 pm
PTY
- TRN
1 stop20h 50m
Multiple Airlines
Sun 10/116:00 am
TRN
- PTY
1 stop20h 45m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$855
This Turkish Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:45 pm
PTY
- FCO
1 stop18h 10m
Turkish Airlines
Tue 11/177:45 pm
FCO
- PTY
1 stop30h 20m
Turkish Airlines
Deal found 6/15![Turkish Airlines logo]()
$856
This Air France deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:55 pm
PTY
- MXP
1 stop18h 05m
Air France
Wed 10/286:55 am
MXP
- PTY
1 stop19h 25m
Air France
Deal found 6/15![Air France logo]()
$858
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:50 pm
PTY
- LIN
1 stop19h 30m
Multiple Airlines
Fri 10/912:20 pm
LIN
- PTY
1 stop14h 25m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$861
This Air Europa deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:25 pm
PTY
- MXP
1 stop13h 50m
Air Europa
Sun 9/203:45 pm
MXP
- PTY
1 stop33h 55m
Air Europa
Deal found 6/12![Air Europa logo]()
$863
This Air France deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:50 pm
PTY
- TRN
1 stop33h 25m
Multiple Airlines
Sat 10/105:45 pm
TRN
- PTY
1 stop33h 00m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$868
Best flights from Panama City to ItalyDiscover carefully curated flight deals from Panama City to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2026.
Discover carefully curated flight deals from Panama City to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2026.
This Turkish Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:20 pm
PTY
- MXP
1 stop32h 50m
Turkish Airlines
Fri 10/236:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 6/17![Turkish Airlines logo]()
$844
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:50 pm
PTY
- TRN
1 stop20h 50m
Multiple Airlines
Sun 10/116:00 am
TRN
- PTY
1 stop20h 45m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$855
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:55 pm
PTY
- TRN
2 stops17h 45m
KLM
Fri 10/96:05 am
TRN
- PTY
2 stops20h 40m
KLM
Deal found 6/13![KLM logo]()
$920
This KLM deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:55 pm
PTY
- LIN
1 stop14h 50m
Air France
Wed 8/268:45 pm
LIN
- PTY
2 stops27h 05m
Air France
Deal found 6/17![Air France logo]()
$926
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/129:45 am
PTY
- NAP
1 stop18h 55m
United Airlines
Sun 7/192:00 pm
NAP
- PTY
1 stop21h 04m
United Airlines
Deal found 6/12![United Airlines logo]()
$928
This Air Europa deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:25 pm
PTY
- TRS
2 stops59h 05m
Air Europa
Mon 9/2811:15 am
TRS
- PTY
2 stops38h 25m
Air Europa
Deal found 6/15![Air Europa logo]()
$1,532
This Turkish Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:45 pm
PTY
- FCO
1 stop30h 05m
Turkish Airlines
Tue 11/177:45 pm
FCO
- PTY
1 stop30h 20m
Turkish Airlines
Deal found 6/13![Turkish Airlines logo]()
$856
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:50 pm
PTY
- LIN
1 stop19h 30m
Multiple Airlines
Sun 10/116:25 am
LIN
- PTY
1 stop20h 20m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$861
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:30 pm
PTY
- MXP
2 stops38h 50m
United Airlines
Wed 9/99:45 am
MXP
- PTY
1 stop16h 46m
United Airlines
Deal found 6/17![United Airlines logo]()
$929
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:50 pm
PTY
- LIN
1 stop19h 30m
Multiple Airlines
Fri 10/912:20 pm
LIN
- PTY
1 stop14h 25m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$861
This Turkish Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:20 pm
PTY
- BLQ
1 stop37h 00m
Turkish Airlines
Tue 10/62:55 pm
BLQ
- PTY
1 stop36h 30m
Turkish Airlines
Deal found 6/15![Turkish Airlines logo]()
$910
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:45 am
PTY
- MXP
2 stops20h 35m
United Airlines
Wed 8/2612:20 pm
MXP
- PTY
2 stops38h 11m
United Airlines
Deal found 6/17![United Airlines logo]()
$942
This KLM deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:50 pm
PTY
- LIN
1 stop19h 30m
KLM
Fri 10/2310:10 pm
LIN
- PTY
1 stop25h 40m
KLM
Deal found 6/14![KLM logo]()
$1,063
This KLM deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:55 pm
PTY
- FCO
2 stops17h 50m
Multiple Airlines
Tue 10/136:05 am
FCO
- PTY
2 stops17h 45m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$928
This Turkish Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:45 pm
PTY
- FCO
1 stop30h 05m
Turkish Airlines
Mon 11/236:40 am
FCO
- PTY
1 stop19h 25m
Turkish Airlines
Deal found 6/14![Turkish Airlines logo]()
$931
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:00 am
PTY
- MXP
2 stops62h 30m
United Airlines
Sun 9/2710:40 am
MXP
- PTY
2 stops39h 51m
United Airlines
Deal found 6/14![United Airlines logo]()
$945
This KLM deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/204:25 pm
PTY
- FLR
2 stops17h 50m
Air France
Sun 9/2712:25 pm
FLR
- PTY
1 stop14h 20m
Air France
Deal found 6/17![Air France logo]()
$1,148
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:55 pm
PTY
- TRN
2 stops17h 45m
KLM
Sat 10/105:45 pm
TRN
- PTY
2 stops30h 05m
KLM
Deal found 6/13![KLM logo]()
$1,082
This Turkish Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:50 pm
PTY
- MXP
1 stop36h 20m
Turkish Airlines
Wed 11/46:55 am
MXP
- PTY
1 stop19h 10m
Turkish Airlines
Deal found 6/14![Turkish Airlines logo]()
$936
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:45 am
PTY
- MXP
2 stops44h 35m
United Airlines
Sun 10/1110:40 am
MXP
- PTY
2 stops39h 51m
United Airlines
Deal found 6/13![United Airlines logo]()
$945
This KLM deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:21 pm
PTY
- LIN
2 stops17h 34m
Multiple Airlines
Wed 11/46:30 am
LIN
- PTY
2 stops19h 50m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$964
This KLM deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:20 pm
PTY
- FLR
2 stops19h 55m
Air France
Mon 8/109:50 am
FLR
- PTY
1 stop16h 55m
Air France
Deal found 6/14![Air France logo]()
$1,170
This KLM deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:55 pm
PTY
- TRN
2 stops17h 45m
KLM
Mon 9/216:05 am
TRN
- PTY
2 stops20h 40m
KLM
Deal found 6/15![KLM logo]()
$1,121
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/239:45 am
PTY
- FCO
1 stop18h 10m
United Airlines
Thu 7/3012:55 pm
FCO
- PTY
1 stop22h 09m
United Airlines
Deal found 6/17![United Airlines logo]()
$945
This KLM deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:55 pm
PTY
- LIN
2 stops17h 55m
Multiple Airlines
Wed 8/268:45 pm
LIN
- PTY
2 stops27h 05m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$996
This Turkish Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:20 pm
PTY
- TRN
1 stop36h 35m
Turkish Airlines
Mon 9/2110:25 am
TRN
- PTY
2 stops39h 00m
Turkish Airlines
Deal found 6/14![Turkish Airlines logo]()
$1,016
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:30 pm
PTY
- FCO
2 stops33h 45m
United Airlines
Wed 9/910:20 am
FCO
- PTY
2 stops40h 11m
United Airlines
Deal found 6/16![United Airlines logo]()
$945
This Turkish Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:10 pm
PTY
- TRN
1 stop30h 20m
Turkish Airlines
Wed 10/216:50 pm
TRN
- PTY
2 stops30h 40m
Turkish Airlines
Deal found 6/13![Turkish Airlines logo]()
$1,018
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:45 am
PTY
- FCO
1 stop18h 10m
United Airlines
Thu 7/3011:00 am
FCO
- PTY
1 stop24h 04m
United Airlines
Deal found 6/17![United Airlines logo]()
$945
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:50 pm
PTY
- LIN
1 stop17h 10m
Multiple Airlines
Fri 10/96:25 am
LIN
- PTY
1 stop20h 20m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$1,071
Last-minute flights from Panama City to ItalyDiscover last-minute flight deals from Panama City to Italy. Data last updated June 17, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Italy. Data last updated June 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/127:55 am
PTY
- NAP
2 stops20h 45m
United Airlines
Sun 7/199:45 am
NAP
- PTY
2 stops35h 29m
United Airlines
Deal found 6/12![United Airlines logo]()
$928
This Air Europa deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:25 pm
PTY
- MXP
1 stop35h 30m
Air Europa
Mon 9/213:45 pm
MXP
- PTY
1 stop33h 55m
Air Europa
Deal found 6/12![Air Europa logo]()
$871
This Air Europa deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:25 pm
PTY
- FCO
1 stop14h 00m
Air Europa
Mon 9/214:35 pm
FCO
- PTY
1 stop33h 05m
Air Europa
Deal found 6/12![Air Europa logo]()
$874
This Air Europa deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:25 pm
PTY
- FCO
1 stop14h 00m
Air Europa
Wed 9/2310:30 am
FCO
- PTY
1 stop15h 10m
Air Europa
Deal found 6/12![Air Europa logo]()
$927
This Air Europa deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:25 pm
PTY
- MXP
1 stop13h 50m
Air Europa
Sun 9/203:45 pm
MXP
- PTY
1 stop33h 55m
Air Europa
Deal found 6/12![Air Europa logo]()
$863
This KLM deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:50 pm
PTY
- FCO
1 stop20h 55m
KLM
Tue 9/226:30 am
FCO
- PTY
2 stops20h 50m
KLM
Deal found 6/12![KLM logo]()
$901
This KLM deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:50 pm
PTY
- LIN
1 stop21h 00m
Multiple Airlines
Tue 9/226:25 am
LIN
- PTY
1 stop20h 20m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$820
This KLM deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:25 pm
PTY
- LIN
2 stops20h 20m
Air France
Tue 9/226:25 am
LIN
- PTY
1 stop20h 20m
Air France
Deal found 6/12![Air France logo]()
$879
This KLM deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:50 pm
PTY
- FCO
1 stop20h 55m
KLM
Tue 9/226:30 am
FCO
- PTY
2 stops20h 50m
KLM
Deal found 6/12![KLM logo]()
$907
This KLM deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/239:55 pm
PTY
- FCO
1 stop14h 10m
Multiple Airlines
Tue 9/226:30 am
FCO
- PTY
2 stops20h 50m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$902
This Air Europa deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:25 pm
PTY
- MXP
1 stop13h 50m
Air Europa
Fri 9/183:45 pm
MXP
- PTY
1 stop33h 55m
Air Europa
Deal found 6/12![Air Europa logo]()
$895
This Air Europa deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:25 pm
PTY
- FCO
1 stop14h 00m
Air Europa
Thu 9/244:35 pm
FCO
- PTY
1 stop33h 05m
Air Europa
Deal found 6/12![Air Europa logo]()
$906
One-way flights from Panama City to ItalySearch for one-way flight options from Panama City to Italy. Find affordable one-way fares based on user searches. Data last updated June 17, 2026.
Search for one-way flight options from Panama City to Italy. Find affordable one-way fares based on user searches. Data last updated June 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:42 pm
PTY
- FCO
2 stops46h 48m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/69:39 am
PTY
- FCO
3 stops31h 01m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$551
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:50 pm
PTY
- FCO
3 stops39h 35m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$584
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:25 am
PTY
- MXP
3 stops36h 10m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$594
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/54:25 am
PTY
- FCO
3 stops38h 00m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$599
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:10 am
PTY
- FCO
3 stops29h 30m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$615
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:45 am
PTY
- TRN
3 stops47h 10m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:10 pm
PTY
- FCO
2 stops40h 20m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$626
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/23:50 pm
PTY
- FCO
2 stops39h 40m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$650
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/293:50 pm
PTY
- FCO
3 stops44h 25m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$664
This Gotogate deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:25 pm
PTY
- MXP
1 stop35h 30m
Air Europa
Deal found 6/15![Air Europa logo]()
$689
This British Airways deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/179:05 pm
PTY
- LIN
1 stop15h 30m
Iberia
Deal found 6/15![Iberia logo]()
$689
Find flight deals from Panama City to Italy
Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated June 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $820 (KLM) |
One-way from | $549 (Kiwi.com) |
Popular in | January |
Cheapest in | April |
Average price | $943 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Wed 10/7
10:20 pm-2:10 pm
1 stop32h 50m
Milan Malpensa
Fri 10/23
6:50 am-8:25 pm
1 stop20h 35m
$844
Panama CityTurin
PTY - TRN
PTYTRN
Panama City Tocumen Intl
Sun 10/4
6:50 pm-10:40 pm
1 stop20h 50m
Turin Citta Di Torino
Sun 10/11
6:00 am-7:45 pm
1 stop20h 45m
$855
Panama CityRome
PTY - FCO
PTYFCO
Panama City Tocumen Intl
Fri 11/13
9:45 pm-9:50 am
1 stop30h 05m
Rome Fiumicino
Tue 11/17
7:45 pm-8:05 pm
1 stop30h 20m
$856
Panama CityMilan
PTY - LIN
PTYLIN
Panama City Tocumen Intl
Sun 10/4
6:50 pm-9:20 pm
1 stop19h 30m
Milan Linate
Sun 10/11
6:25 am-7:45 pm
1 stop20h 20m
$861
Panama CityMilan
PTY - LIN
PTYLIN
Panama City Tocumen Intl
Sun 10/4
6:50 pm-9:20 pm
1 stop19h 30m
Milan Linate
Fri 10/9
12:20 pm-7:45 pm
1 stop14h 25m
$861
Panama CityBologna
PTY - BLQ
PTYBLQ
Panama City Tocumen Intl
Fri 10/2
10:20 pm-6:20 pm
1 stop37h 00m
Bologna Guglielmo Marconi
Tue 10/6
2:55 pm-8:25 pm
1 stop36h 30m
$910
Panama CityTurin
PTY - TRN
PTYTRN
Panama City Tocumen Intl
Sun 10/4
9:55 pm-10:40 pm
2 stops17h 45m
Turin Citta Di Torino
Fri 10/9
6:05 am-7:45 pm
2 stops20h 40m
$920
Panama CityMilan
PTY - LIN
PTYLIN
Panama City Tocumen Intl
Thu 8/6
9:55 pm-7:45 pm
1 stop14h 50m
Milan Linate
Wed 8/26
8:45 pm-4:50 pm
2 stops27h 05m
$926
Panama CityNaples
PTY - NAP
PTYNAP
Panama City Tocumen Intl
Sun 7/12
9:45 am-11:40 am
1 stop18h 55m
Naples
Sun 7/19
2:00 pm-4:04 am
1 stop21h 04m
$928
Panama CityRome
PTY - FCO
PTYFCO
Panama City Tocumen Intl
Thu 10/1
9:55 pm-10:45 pm
2 stops17h 50m
Rome Fiumicino
Tue 10/13
6:05 am-4:50 pm
2 stops17h 45m
$928
Showing 1-10 of 56 resultsSorted by cheapest first
Best time to book a flight from Panama City to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
PTY-LIN
PTY-MXP
PTY-FCO
PTY-NAP
PTY-TRN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Italy
PTY-IT0
PTY-LIN
PTY-MXP
PTY-FCO
PTY-NAP
What is the cheapest month to book a flight from Panama City to Italy?
Currently, September is the cheapest month in which you can book a flight from Panama City to Italy (average of $312). Flying from Panama City to Italy in January is currently the most expensive (average of $635). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Panama City to Italy?
The best time to book flights from Panama City to Italy is 44 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Italy
Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated June 17, 2026.
Get a feel of what it's like to fly with KLM,Air France, andTurkish Airlines from Panama City to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Entertainment
7.2
Crew
8.4
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Boarding
7.8
Entertainment
7.2
Crew
8.4
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Boarding
7.8
Entertainment
7.2
Crew
8.4
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Boarding
7.8
Entertainment
7.2
Crew
8.4
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Boarding
7.8
Entertainment
7.2
Crew
8.4
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Boarding
7.8
Entertainment
7.2
Crew
8.4
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Italy by cabin class
Find flights from Panama City to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Italy flights
Browse other Panama City and Italy flight options. Last updated on June 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 3 airlines flying from Panama City to Italy
Discover the top 3 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$679 | Average$1,102 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$690 | Average$854 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$883 | Average$972 | FlexibilityNo cancel fee | On-time77% |