HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Italy

$449+ Cheap flights from Panama City (PTY) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated junio 12, 2025.

Round-trip from

$519
(FlightHub)

One-way from

$449
(Kiwi.com)

Popular in

August

Cheapest in

March

Average price

$897
From Panama City Tocumen Intl to Italy
Search Deals
One-way flight from Panama City Tocumen Intl to Italy
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($80 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Turkish Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/59:45 pmPTY - MXP
1 stop17h 55mTurkish Airlines
sáb. 11/156:55 amMXP - PTY
1 stop18h 55mTurkish Airlines
Deal found 6/10$688
This Turkish Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 6/229:55 pmPTY - VCE
1 stop38h 00mTurkish Airlines
mar. 7/17:55 pmVCE - PTY
1 stop31h 05mTurkish Airlines
Deal found 6/10$709
This Turkish Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/179:55 pmPTY - FCO
1 stop28h 25mTurkish Airlines
dom. 11/22:50 pmFCO - PTY
1 stop35h 00mTurkish Airlines
Deal found 6/9$726
This KLM deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/167:55 pmPTY - FCO
1 stop14h 35mMultiple Airlines
vie. 9/265:25 pmFCO - PTY
1 stop30h 25mMultiple Airlines
Deal found 6/11$784
This Air France deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/97:55 pmPTY - FCO
1 stop30h 00mAir France
jue. 9/256:05 amFCO - PTY
1 stop18h 40mAir France
Deal found 6/10$786
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/1611:05 amPTY - MXP
2 stops29h 00mMultiple Airlines
dom. 6/225:35 pmMXP - PTY
1 stop16h 05mMultiple Airlines
Deal found 6/11$792
This Iberia deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 6/155:10 pmPTY - FCO
1 stop13h 45mIberia
jue. 6/197:35 amFCO - PTY
1 stop15h 05mIberia
Deal found 6/9$804
This FlightHub deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/158:25 pmPTY - MXP
1 stop13h 50mAir Europa
sáb. 11/16:20 pmMXP - PTY
1 stop31h 25mAir Europa
Deal found 6/10$805
This Air Europa deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/78:25 pmPTY - FCO
1 stop14h 00mAir Europa
sáb. 10/1110:30 amFCO - PTY
1 stop15h 10mAir Europa
Deal found 6/10$806
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/1611:05 amPTY - LIN
2 stops22h 05mMultiple Airlines
dom. 6/228:00 amLIN - PTY
2 stops25h 40mMultiple Airlines
Deal found 6/11$812
This FlightHub deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/1611:05 amPTY - MXP
1 stop13h 55mCondor
dom. 6/225:35 pmMXP - PTY
1 stop16h 05mCondor
Deal found 6/10$814
This Turkish Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/29:55 pmPTY - NAP
1 stop34h 05mTurkish Airlines
mié. 7/239:20 amNAP - PTY
1 stop17h 40mTurkish Airlines
Deal found 6/10$815

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

mié. 11/5

9:45 pm-9:40 pm

1 stop17h 55m

Milan Malpensa

sáb. 11/15

6:55 am-7:50 pm

1 stop18h 55m

$688

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

dom. 6/22

9:55 pm-6:55 pm

1 stop38h 00m

Venice Marco Polo

mar. 7/1

7:55 pm-8:00 pm

1 stop31h 05m

$709

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

vie. 10/17

9:55 pm-9:20 am

1 stop28h 25m

Rome Fiumicino

dom. 11/2

2:50 pm-7:50 pm

1 stop35h 00m

$726

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

mar. 9/16

7:55 pm-5:30 pm

1 stop14h 35m

Rome Fiumicino

vie. 9/26

5:25 pm-4:50 pm

1 stop30h 25m

$784

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

mar. 9/9

7:55 pm-8:55 am

1 stop30h 00m

Rome Fiumicino

jue. 9/25

6:05 am-5:45 pm

1 stop18h 40m

$786

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

mié. 10/15

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

sáb. 11/1

6:20 pm-7:45 pm

1 stop31h 25m

$805

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

mar. 10/7

8:25 pm-5:25 pm

1 stop14h 00m

Rome Fiumicino

sáb. 10/11

10:30 am-6:40 pm

1 stop15h 10m

$806

Panama CityNaples

PTY - NAP

PTYNAP

Panama City Tocumen Intl

mié. 7/2

9:55 pm-3:00 pm

1 stop34h 05m

Naples

mié. 7/23

9:20 am-8:00 pm

1 stop17h 40m

$815

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

jue. 9/11

6:50 pm-9:25 am

1 stop31h 35m

Rome Fiumicino

sáb. 9/27

7:40 pm-4:50 pm

1 stop28h 10m

$828

Panama CityNaples

PTY - NAP

PTYNAP

Panama City Tocumen Intl

jue. 7/31

7:55 pm-10:05 pm

1 stop19h 10m

Naples

jue. 8/21

10:10 pm-4:50 pm

1 stop25h 40m

$829

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City to Italy?

Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Italy as you normally would.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated junio 12, 2025.
Read through reviews of airlines operating flights from Panama City to Italy, such as Emirates, Delta and KLM. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Emirates
8.1
Very good
3,264 reviews

Food

7.8

Overall

8.1

Comfort

8.0

Entertainment

8.2

Boarding

8.1

Crew

8.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2024

AKL - DXB

The cabin crew were as always friendly and helpful. Couldn't ask for more. Although the flight in business was under occupied there were a couple of things not available!
Emirates
8.1
Very good
3,264 reviews
Emirates
8.1
Very good
3,264 reviews

Food

7.8

Overall

8.1

Comfort

8.0

Entertainment

8.2

Boarding

8.1

Crew

8.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2024

AKL - DXB

The cabin crew were as always friendly and helpful. Couldn't ask for more. Although the flight in business was under occupied there were a couple of things not available!
Delta
8.0
Very good
7,950 reviews
Emirates
8.1
Very good
3,264 reviews

Food

7.8

Overall

8.1

Comfort

8.0

Entertainment

8.2

Boarding

8.1

Crew

8.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2024

AKL - DXB

The cabin crew were as always friendly and helpful. Couldn't ask for more. Although the flight in business was under occupied there were a couple of things not available!
KLM
7.8
Good
1,358 reviews
Emirates
8.1
Very good
3,264 reviews

Food

7.8

Overall

8.1

Comfort

8.0

Entertainment

8.2

Boarding

8.1

Crew

8.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2024

AKL - DXB

The cabin crew were as always friendly and helpful. Couldn't ask for more. Although the flight in business was under occupied there were a couple of things not available!
Air France
7.5
Good
1,463 reviews
Emirates
8.1
Very good
3,264 reviews

Food

7.8

Overall

8.1

Comfort

8.0

Entertainment

8.2

Boarding

8.1

Crew

8.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2024

AKL - DXB

The cabin crew were as always friendly and helpful. Couldn't ask for more. Although the flight in business was under occupied there were a couple of things not available!
United Airlines
7.4
Good
8,790 reviews
Emirates
8.1
Very good
3,264 reviews

Food

7.8

Overall

8.1

Comfort

8.0

Entertainment

8.2

Boarding

8.1

Crew

8.3

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2024

AKL - DXB

The cabin crew were as always friendly and helpful. Couldn't ask for more. Although the flight in business was under occupied there were a couple of things not available!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Most people fly from Panama City Tocumen Intl (PTY) if they book a flight from Panama City to Italy. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to Italy one-way?

    For one-way options, check prices for Air Europa. According to our data, you can fly for as low as $525. Users have also found prices from $540 and $540 on Air France and KLM, respectively.

  • What are the most popular routes from Panama City to Italy?

    When deciding which route to take from Panama City to Italy consider Panama City Tocumen Intl - Milan Linate, Panama City Tocumen Intl - Rome Fiumicino or Panama City Tocumen Intl - Milan Malpensa as they are the most popular.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Italy?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Panama City to Italy

Discover the top 5 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$692Average$856FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$746Average$904FlexibilityNo cancel feeOn-time83%
IberiaCheapest$747Average$886FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$781Average$919FlexibilityNo cancel feeOn-time77%
KLMCheapest$796Average$1,469FlexibilityNo cancel feeOn-time75%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.