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Italy

$381+ Cheap flights from Panama City (PTY) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated August 20, 2025.

Round-trip from

$616
(Condor)

One-way from

$381
(Kiwi.com)

Popular in

January

Cheapest in

March

Average price

$909
From Panama City Tocumen Intl to Italy
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One-way flight from Panama City Tocumen Intl to Italy
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Highest demand for flights based on searches. 6% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Condor deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Condor is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1811:05 amPTY - FCO
1 stop22h 50mCondor
Sun 9/288:20 amFCO - PTY
1 stop25h 20mCondor
Deal found 8/18$616
This Condor deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Condor is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1511:05 amPTY - FCO
1 stop22h 50mCondor
Sun 9/288:20 amFCO - PTY
1 stop25h 20mCondor
Deal found 8/19$642
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2111:05 amPTY - FCO
1 stop22h 50mCondor
Sun 8/318:20 amFCO - PTY
1 stop25h 20mCondor
Deal found 8/19$668
This Booking.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:45 pmPTY - FCO
1 stop38h 50mTurkish Airlines
Sat 11/226:45 amFCO - PTY
1 stop19h 05mTurkish Airlines
Deal found 8/20$691
This Turkish Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/59:45 pmPTY - FCO
1 stop38h 35mTurkish Airlines
Mon 11/176:45 amFCO - PTY
1 stop19h 05mTurkish Airlines
Deal found 8/18$705
This Booking.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/129:55 pmPTY - MXP
1 stop33h 15mTurkish Airlines
Sun 9/286:50 amMXP - PTY
2 stops42h 30mTurkish Airlines
Deal found 8/18$712
This deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/248:25 pmPTY - VCE
1 stop14h 10mAir Europa
Wed 10/2210:45 amVCE - PTY
1 stop14h 55mAir Europa
Deal found 8/17$725
This Turkish Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:55 pmPTY - FCO
1 stop28h 25mTurkish Airlines
Sun 11/211:15 amFCO - PTY
1 stop38h 35mTurkish Airlines
Deal found 8/18$726
This Booking.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/168:00 pmPTY - MXP
1 stop29h 45mTurkish Airlines
Tue 10/2110:45 amMXP - PTY
1 stop40h 15mTurkish Airlines
Deal found 8/18$733
This Turkish Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/109:55 pmPTY - FCO
1 stop18h 35mTurkish Airlines
Wed 9/247:00 amFCO - PTY
1 stop20h 00mTurkish Airlines
Deal found 8/18$747
This deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/238:25 pmPTY - VCE
1 stop14h 10mAir Europa
Fri 10/2410:45 amVCE - PTY
1 stop14h 55mAir Europa
Deal found 8/17$751
This Turkish Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/149:55 pmPTY - VCE
1 stop27h 25mTurkish Airlines
Sat 10/112:05 pmVCE - PTY
1 stop36h 55mTurkish Airlines
Deal found 8/18$755

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 9/18

11:05 am-4:55 pm

1 stop22h 50m

Rome Fiumicino

Sun 9/28

8:20 am-2:40 am

1 stop25h 20m

$616

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 9/15

11:05 am-4:55 pm

1 stop22h 50m

Rome Fiumicino

Sun 9/28

8:20 am-2:40 am

1 stop25h 20m

$642

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 11/8

9:45 pm-6:35 pm

1 stop38h 50m

Rome Fiumicino

Sat 11/22

6:45 am-7:50 pm

1 stop19h 05m

$691

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 11/5

9:45 pm-6:20 pm

1 stop38h 35m

Rome Fiumicino

Mon 11/17

6:45 am-7:50 pm

1 stop19h 05m

$705

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Fri 9/12

9:55 pm-2:10 pm

1 stop33h 15m

Milan Malpensa

Sun 9/28

6:50 am-6:20 pm

2 stops42h 30m

$712

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

Wed 9/24

8:25 pm-5:35 pm

1 stop14h 10m

Venice Marco Polo

Tue 10/21

10:45 am-6:40 pm

1 stop14h 55m

$725

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

Wed 9/24

8:25 pm-5:35 pm

1 stop14h 10m

Venice Marco Polo

Wed 10/22

10:45 am-6:40 pm

1 stop14h 55m

$725

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

Wed 9/24

8:25 pm-5:35 pm

1 stop14h 10m

Venice Marco Polo

Sun 10/19

10:45 am-6:40 pm

1 stop14h 55m

$725

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

Wed 9/24

8:25 pm-5:35 pm

1 stop14h 10m

Venice Marco Polo

Fri 10/24

10:45 am-6:40 pm

1 stop14h 55m

$725

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

Wed 9/24

8:25 pm-5:35 pm

1 stop14h 10m

Venice Marco Polo

Mon 10/20

10:45 am-6:40 pm

1 stop14h 55m

$725

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 55 results
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Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City to Italy?

Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Italy as you normally would.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated August 20, 2025.
Get a feel of what it's like to fly with Air France, United Airlines, and Turkish Airlines from Panama City to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,469 reviews

Food

7.0

Boarding

7.4

Crew

8.1

Entertainment

6.9

Comfort

7.4

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Air France
7.4
Good
1,469 reviews
Air France
7.4
Good
1,469 reviews

Food

7.0

Boarding

7.4

Crew

8.1

Entertainment

6.9

Comfort

7.4

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
United Airlines
7.4
Good
8,928 reviews
Air France
7.4
Good
1,469 reviews

Food

7.0

Boarding

7.4

Crew

8.1

Entertainment

6.9

Comfort

7.4

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Turkish Airlines
7.3
Good
3,949 reviews
Air France
7.4
Good
1,469 reviews

Food

7.0

Boarding

7.4

Crew

8.1

Entertainment

6.9

Comfort

7.4

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Air Europa
7.0
Good
547 reviews
Air France
7.4
Good
1,469 reviews

Food

7.0

Boarding

7.4

Crew

8.1

Entertainment

6.9

Comfort

7.4

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Iberia
7.0
Good
2,883 reviews
Air France
7.4
Good
1,469 reviews

Food

7.0

Boarding

7.4

Crew

8.1

Entertainment

6.9

Comfort

7.4

Overall

7.4

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Most people fly from Panama City Tocumen Intl (PTY) if they book a flight from Panama City to Italy. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • How long is the flight from Panama City to Italy?

    Airlines like Condor, Turkish Airlines, and Air Europa fly from Panama City to Italy in about 14h 10m. The time it takes to get you to your destination can typically vary by up to 24h 40m. The distance between Panama City and Italy is about 5851 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Panama City to Italy one-way?

    For one-way options, check prices for KLM. According to our data, you can fly for as low as $652. Users have also found prices from $653 and $812 on Turkish Airlines and United Airlines, respectively.

  • What are the most popular routes from Panama City to Italy?

    When deciding which route to take from Panama City to Italy consider Panama City Tocumen Intl - Rome Fiumicino, Panama City Tocumen Intl - Trieste Ronchi dei Legionari or Panama City Tocumen Intl - Milan Malpensa as they are the most popular.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Italy?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Panama City to Italy

Discover the top 4 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$692Average$788FlexibilityNo cancel feeOn-time77%
IberiaCheapest$747Average$886FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$771Average$1,003FlexibilityNo cancel feeOn-time83%
Air FranceCheapest$783Average$909FlexibilityNo cancel feeOn-time77%

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