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Italy

$595+ Cheap flights from Panama City (PTY) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This Turkish Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:20 pm
PTY
-
FCO
1 stop28h 00m
Turkish Airlines
Fri 4/1710:45 am
FCO
-
PTY
2 stops38h 45m
Turkish Airlines
Deal found 3/17$707
This Booking.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2510:20 pm
PTY
-
FCO
1 stop37h 05m
Turkish Airlines
Wed 6/37:05 am
FCO
-
PTY
1 stop20h 20m
Turkish Airlines
Deal found 3/17$708
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:20 pm
PTY
-
VCE
1 stop27h 00m
Turkish Airlines
Sun 4/192:05 pm
VCE
-
PTY
1 stop37h 20m
Turkish Airlines
Deal found 3/18$709
This Turkish Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:20 pm
PTY
-
FCO
1 stop32h 45m
Turkish Airlines
Fri 5/87:05 am
FCO
-
PTY
2 stops42h 25m
Turkish Airlines
Deal found 3/18$718
This Booking.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:20 pm
PTY
-
MXP
1 stop18h 25m
Turkish Airlines
Wed 5/137:45 pm
MXP
-
PTY
2 stops29h 45m
Turkish Airlines
Deal found 3/17$724
This Booking.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:20 pm
PTY
-
MXP
1 stop32h 50m
Turkish Airlines
Wed 6/176:50 am
MXP
-
PTY
1 stop20h 35m
Turkish Airlines
Deal found 3/20$726
This Turkish Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:20 pm
PTY
-
MXP
1 stop18h 25m
Turkish Airlines
Wed 4/296:50 am
MXP
-
PTY
1 stop20h 35m
Turkish Airlines
Deal found 3/16$727
This Booking.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:20 pm
PTY
-
FCO
1 stop37h 05m
Turkish Airlines
Fri 5/158:00 pm
FCO
-
PTY
1 stop31h 25m
Turkish Airlines
Deal found 3/20$728
This Turkish Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:20 pm
PTY
-
FCO
1 stop28h 00m
Turkish Airlines
Mon 6/18:00 pm
FCO
-
PTY
2 stops29h 25m
Turkish Airlines
Deal found 3/17$729
This SmartFares deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:20 pm
PTY
-
FCO
1 stop37h 05m
Turkish Airlines
Wed 5/67:05 am
FCO
-
PTY
1 stop20h 20m
Turkish Airlines
Deal found 3/17$737
This Turkish Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:20 pm
PTY
-
MXP
1 stop36h 40m
Turkish Airlines
Fri 5/157:45 pm
MXP
-
PTY
1 stop31h 40m
Turkish Airlines
Deal found 3/20$738
This Turkish Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:20 pm
PTY
-
FCO
1 stop37h 05m
Turkish Airlines
Wed 5/67:05 am
FCO
-
PTY
1 stop20h 20m
Turkish Airlines
Deal found 3/18$739

Find flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$698
(CheapOair)

One-way from

$595
(Kiwi.com)

Popular in

January

Cheapest in

April

Average price

$875
Provider with most accurate pricing for Panama City Tocumen Intl-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Rome (ROM) flights.
Search Deals
From Panama City Tocumen Intl to Italy
Search Deals
One-way flight from Panama City Tocumen Intl to Italy
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 4/13

10:20 pm-9:20 am

1 stop28h 00m

Rome Fiumicino

Fri 4/17

10:45 am-6:30 pm

2 stops38h 45m

$707

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

Mon 4/6

10:20 pm-7:00 pm

1 stop37h 40m

Venice Marco Polo

Sun 4/19

2:05 pm-8:25 pm

1 stop37h 20m

$731

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Wed 5/6

10:20 pm-8:40 am

1 stop27h 20m

Milan Malpensa

Fri 5/15

3:15 pm-8:25 pm

1 stop36h 10m

$738

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 5/26

8:05 pm-9:20 am

1 stop30h 15m

Rome Fiumicino

Sun 6/28

8:00 pm-8:25 pm

1 stop31h 25m

$762

Panama CityNaples

PTY - NAP

PTYNAP

Panama City Tocumen Intl

Mon 5/18

10:20 pm-2:35 pm

1 stop33h 15m

Naples

Tue 6/2

8:45 pm-8:25 pm

1 stop30h 40m

$762

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Sat 5/9

10:20 pm-5:45 pm

1 stop36h 25m

Milan Malpensa

Sun 5/31

7:35 pm-8:25 pm

1 stop31h 50m

$781

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Wed 4/15

8:05 pm-11:45 pm

1 stop20h 40m

Milan Malpensa

Wed 4/29

6:50 am-8:25 pm

1 stop20h 35m

$787

Panama CityTurin

PTY - TRN

PTYTRN

Panama City Tocumen Intl

Thu 5/7

8:10 pm-9:30 am

1 stop30h 20m

Turin Citta Di Torino

Sun 5/10

6:40 pm-6:30 pm

2 stops30h 50m

$795

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 5/30

10:20 pm-11:35 pm

1 stop18h 15m

Rome Fiumicino

Fri 7/3

3:35 pm-8:25 pm

1 stop35h 50m

$805
Quickest round-trip

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Sun 7/5

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

Thu 8/27

11:05 am-6:40 pm

1 stop14h 35m

$808

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/20

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City to Italy?

Currently, June is the cheapest month in which you can book a flight from Panama City to Italy (average of $384). Flying from Panama City to Italy in January is currently the most expensive (average of $774). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated March 22, 2026.
Get a feel of what it's like to fly with Air France,Turkish Airlines, andIberia from Panama City to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,547 reviews

Comfort

7.3

Boarding

7.4

Overall

7.4

Entertainment

7.0

Crew

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Air France
7.4
Good
1,547 reviews
Air France
7.4
Good
1,547 reviews

Comfort

7.3

Boarding

7.4

Overall

7.4

Entertainment

7.0

Crew

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Turkish Airlines
7.3
Good
4,270 reviews
Air France
7.4
Good
1,547 reviews

Comfort

7.3

Boarding

7.4

Overall

7.4

Entertainment

7.0

Crew

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Iberia
7.0
Good
3,147 reviews
Air France
7.4
Good
1,547 reviews

Comfort

7.3

Boarding

7.4

Overall

7.4

Entertainment

7.0

Crew

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Air Europa
6.9
Okay
597 reviews
Air France
7.4
Good
1,547 reviews

Comfort

7.3

Boarding

7.4

Overall

7.4

Entertainment

7.0

Crew

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Condor
6.5
Okay
401 reviews
Air France
7.4
Good
1,547 reviews

Comfort

7.3

Boarding

7.4

Overall

7.4

Entertainment

7.0

Crew

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Most people fly from Panama City Tocumen Intl (PTY) if they book a flight from Panama City to Italy. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • How long is the flight from Panama City to Italy?

    Airlines like Turkish Airlines, KLM, and Air Europa fly from Panama City to Italy in about 19h 15m. The time it takes to get you to your destination can typically vary by up to 13h. The distance between Panama City and Italy is about 5811 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Panama City to Italy?

    When deciding which route to take from Panama City to Italy consider Panama City Tocumen Intl - Rome Fiumicino, Panama City Tocumen Intl - Trieste Ronchi dei Legionari or Panama City Tocumen Intl - Milan Malpensa as they are the most popular.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Italy?

    Currently, June is the cheapest month in which you can book a flight from Panama City to Italy (average of $384). Flying from Panama City to Italy in January is currently the most expensive (average of $774). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Panama City to Italy

Discover the top 3 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$678Average$774FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$679Average$1,109FlexibilityNo cancel feeOn-time83%
Air FranceCheapest$705Average$928FlexibilityNo cancel feeOn-time77%

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