$575+ Cheap flights from Panama City (PTY) to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
Oct 18 — Oct 251
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Panama City to Italy with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Italy
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to ItalyExplore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
This Air Europa deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:30 pm -
1 stop13h 55m
Sat 11/2110:30 am -
1 stop15h 15m
Deal found 9/14![Air Europa logo]()
$801
This Air Europa deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:30 pm -
1 stop13h 55m
Mon 11/233:55 pm -
1 stop33h 50m
Deal found 9/14![Air Europa logo]()
$809
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:30 pm -
1 stop13h 55m
Sat 10/316:25 pm -
1 stop31h 20m
Deal found 9/14![Air Europa logo]()
$812
This Air Europa deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:30 pm -
1 stop13h 55m
Mon 11/233:55 pm -
1 stop33h 50m
Deal found 9/14![Air Europa logo]()
$813
This Air Europa deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop13h 55m
Mon 10/2610:20 am -
1 stop15h 25m
Deal found 9/13![Air Europa logo]()
$822
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:30 pm -
1 stop13h 55m
Wed 11/1110:30 am -
1 stop15h 15m
Deal found 9/17![Air Europa logo]()
$832
This Air Europa deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:30 pm -
1 stop13h 55m
Thu 11/2610:30 am -
1 stop15h 15m
Deal found 9/16![Air Europa logo]()
$833
This Air Europa deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:25 pm -
1 stop14h 10m
Sat 10/246:35 pm -
1 stop32h 10m
Deal found 9/16![Air Europa logo]()
$835
This Air Europa deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:30 pm -
1 stop35h 25m
Thu 11/2610:30 am -
1 stop15h 15m
Deal found 9/14![Air Europa logo]()
$842
This Gotogate deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:00 pm -
1 stop36h 50m
Thu 11/266:50 pm -
1 stop31h 15m
Deal found 9/16![Turkish Airlines logo]()
$845
This Turkish Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:20 pm -
1 stop27h 00m
Fri 10/239:20 am -
1 stop18h 05m
Deal found 9/16![Turkish Airlines logo]()
$860
This Air Europa deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 pm -
1 stop35h 20m
Mon 11/910:20 am -
1 stop15h 25m
Deal found 9/13![Air Europa logo]()
$862
Best flights from Panama City to ItalyDiscover carefully curated flight deals from Panama City to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
Discover carefully curated flight deals from Panama City to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:30 pm -
1 stop13h 55m
Mon 11/233:55 pm -
1 stop33h 50m
Deal found 9/17![Air Europa logo]()
$812
This Turkish Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:20 pm -
1 stop27h 00m
Fri 10/239:20 am -
1 stop18h 05m
Deal found 9/16![Turkish Airlines logo]()
$860
This Air France deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 pm -
1 stop18h 35m
Wed 11/2510:40 am -
1 stop15h 40m
Deal found 9/14![Air France logo]()
$883
This KLM deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 pm -
2 stops18h 35m
Wed 11/2510:40 am -
1 stop15h 40m
Deal found 9/14![Multiple Airlines logo]()
$915
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:41 pm -
2 stops38h 34m
Thu 11/263:15 pm -
2 stops34h 23m
Deal found 9/16![United Airlines logo]()
$929
This KLM deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:45 pm -
1 stop15h 40m
Wed 11/256:35 am -
3 stops29h 13m
Deal found 9/14![KLM logo]()
$955
This Orbitz deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:35 pm -
1 stop17h 40m
Sun 11/812:25 pm -
2 stops31h 48m
Deal found 9/14![Iberia logo]()
$1,103
This Air Europa deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:30 pm -
1 stop13h 55m
Thu 11/2610:30 am -
1 stop15h 15m
Deal found 9/15![Air Europa logo]()
$833
This Turkish Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/46:50 pm -
1 stop18h 00m
Mon 3/19:35 am -
2 stops37h 35m
Deal found 9/16![Turkish Airlines logo]()
$860
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:45 am -
1 stop15h 45m
Mon 11/99:45 am -
1 stop16h 17m
Deal found 9/17![United Airlines logo]()
$934
This Air Europa deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/49:30 pm -
1 stop14h 15m
Mon 3/110:20 am -
1 stop15h 25m
Deal found 9/16![Air Europa logo]()
$856
This Turkish Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/146:50 pm -
1 stop33h 20m
Thu 2/2511:05 am -
1 stop39h 00m
Deal found 9/14![Turkish Airlines logo]()
$860
This KLM deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:30 pm -
2 stops18h 25m
Thu 11/126:30 am -
1 stop19h 50m
Deal found 9/17![Multiple Airlines logo]()
$983
This KLM deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:50 pm -
1 stop20h 40m
Sun 10/256:40 am -
3 stops29h 08m
Deal found 9/15![KLM logo]()
$997
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
2 stops42h 05m
Wed 12/99:45 am -
1 stop16h 17m
Deal found 9/16![United Airlines logo]()
$937
This Air Europa deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/139:30 pm -
1 stop30h 00m
Sun 2/283:55 pm -
1 stop33h 50m
Deal found 9/18![Air Europa logo]()
$884
This Turkish Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:00 pm -
1 stop33h 50m
Thu 11/262:50 pm -
1 stop35h 15m
Deal found 9/17![Turkish Airlines logo]()
$902
This KLM deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:30 pm -
2 stops18h 25m
Thu 11/266:30 am -
1 stop16h 00m
Deal found 9/16![KLM logo]()
$1,026
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:00 am -
2 stops39h 45m
Mon 1/1110:30 am -
2 stops34h 15m
Deal found 9/17![United Airlines logo]()
$945
This Air France deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:18 pm -
2 stops18h 52m
Sun 11/86:00 am -
1 stop20h 20m
Deal found 9/17![Air France logo]()
$1,162
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:30 pm -
1 stop35h 30m
Wed 12/910:20 am -
1 stop15h 25m
Deal found 9/17![Air Europa logo]()
$894
This Iberia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/226:10 pm -
2 stops19h 35m
Sun 5/308:20 pm -
2 stops19h 55m
Deal found 9/16![Multiple Airlines logo]()
$1,110
This Turkish Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:00 pm -
1 stop37h 25m
Tue 12/811:05 am -
1 stop39h 00m
Deal found 9/18![Turkish Airlines logo]()
$940
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am -
1 stop15h 55m
Mon 11/231:55 pm -
2 stops30h 50m
Deal found 9/15![United Airlines logo]()
$954
This Air Europa deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:30 pm -
1 stop13h 55m
Wed 11/1110:30 am -
1 stop15h 15m
Deal found 9/18![Air Europa logo]()
$897
This KLM deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:55 pm -
2 stops17h 55m
Sun 10/256:30 am -
1 stop16h 00m
Deal found 9/13![KLM logo]()
$1,113
This KLM deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:55 pm -
2 stops16h 25m
Mon 10/266:30 am -
1 stop19h 50m
Deal found 9/13![Multiple Airlines logo]()
$1,148
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:00 am -
1 stop18h 55m
Thu 11/261:55 pm -
2 stops35h 43m
Deal found 9/15![United Airlines logo]()
$954
This Air Europa deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:25 pm -
1 stop35h 30m
Thu 10/2211:05 am -
1 stop14h 35m
Deal found 9/14![Air Europa logo]()
$931
This Turkish Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1110:00 pm -
1 stop29h 55m
Sun 1/1010:55 am -
1 stop39h 10m
Deal found 9/13![Turkish Airlines logo]()
$1,030
Last-minute flights from Panama City to ItalyDiscover last-minute flight deals from Panama City to Italy. Data last updated September 18, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Italy. Data last updated September 18, 2026 and is based on user searches.
This Gotogate deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:20 pm -
1 stop32h 45m
Tue 10/203:15 pm -
1 stop36h 10m
Deal found 9/13![Turkish Airlines logo]()
$870
This Turkish Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:20 pm -
1 stop27h 00m
Fri 10/239:20 am -
1 stop18h 05m
Deal found 9/16![Turkish Airlines logo]()
$860
This Air Europa deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop13h 55m
Mon 10/2610:20 am -
1 stop15h 25m
Deal found 9/13![Air Europa logo]()
$822
This Air Europa deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop13h 55m
Sat 10/316:20 pm -
1 stop31h 25m
Deal found 9/16![Air Europa logo]()
$864
This Air Europa deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:25 pm -
1 stop14h 10m
Sat 10/246:35 pm -
1 stop32h 10m
Deal found 9/16![Air Europa logo]()
$835
This Air Europa deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 pm -
1 stop13h 55m
Fri 11/203:55 pm -
1 stop33h 50m
Deal found 9/16![Air Europa logo]()
$844
This Air Europa deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 pm -
1 stop30h 00m
Thu 11/53:55 pm -
1 stop33h 50m
Deal found 9/15![Air Europa logo]()
$853
This Air Europa deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 pm -
1 stop35h 20m
Mon 11/910:20 am -
1 stop15h 25m
Deal found 9/13![Air Europa logo]()
$862
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:30 pm -
1 stop13h 55m
Sat 10/316:25 pm -
1 stop31h 20m
Deal found 9/14![Air Europa logo]()
$812
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:30 pm -
1 stop13h 55m
Thu 11/126:25 pm -
1 stop31h 20m
Deal found 9/17![Air Europa logo]()
$842
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:30 pm -
1 stop13h 55m
Wed 11/1110:30 am -
1 stop15h 15m
Deal found 9/17![Air Europa logo]()
$863
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:30 pm -
1 stop13h 55m
Wed 11/1110:30 am -
1 stop15h 15m
Deal found 9/17![Air Europa logo]()
$832
One-way flights from Panama City to ItalySearch for one-way flight options from Panama City to Italy. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
Search for one-way flight options from Panama City to Italy. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
This Booking.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:25 pm -
1 stop14h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Air Europa logo]()
$575
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:25 pm -
2 stops21h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$600
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:25 am -
3 stops32h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$613
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:35 pm -
1 stop18h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Iberia logo]()
$651
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/59:40 am -
3 stops27h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$653
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/106:15 pm -
3 stops39h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$657
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/39:40 am -
3 stops29h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$664
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/36:35 pm -
1 stop17h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Iberia logo]()
$675
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/110:25 am -
2 stops21h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$679
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:33 pm -
2 stops51h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$682
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/110:25 am -
2 stops26h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$682
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:20 pm -
1 stop31h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Turkish Airlines logo]()
$687
Find flight deals from Panama City to Italy
Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated September 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $682 (Expedia) |
One-way from | $575 (Booking.com) |
Popular in | July |
Cheapest in | April |
Average price | $992 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityMilan
PTY Panama City Tocumen Intl - LIN Milan Linate
PTYLIN
Panama City Tocumen Intl
Sun 1/10
6:15 pm-4:10 pm
3 stops39h 55m
Milan Linate
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$657
Panama CityRome
PTY Panama City Tocumen Intl - FCO Rome Fiumicino
PTYFCO
Panama City Tocumen Intl
Fri 12/4
10:25 am-4:55 pm
3 stops24h 30m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$673
Panama CityMilan
PTY Panama City Tocumen Intl - MXP Milan Malpensa
PTYMXP
Panama City Tocumen Intl
Mon 3/1
10:25 am-2:15 pm
2 stops21h 50m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$679
Panama CityMilan
PTY Panama City Tocumen Intl - MXP Milan Malpensa
PTYMXP
Panama City Tocumen Intl
Sun 1/10
9:31 pm-2:15 pm
2 stops34h 44m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$696
Panama CityVenice
PTY Panama City Tocumen Intl - VCE Venice Marco Polo
PTYVCE
Panama City Tocumen Intl
Mon 1/11
10:00 pm-6:50 pm
1 stop38h 50m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$703
Panama CityVenice
PTY Panama City Tocumen Intl - VCE Venice Marco Polo
PTYVCE
Panama City Tocumen Intl
Tue 1/12
10:00 pm-1:50 pm
1 stop33h 50m
Venice Marco Polo
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$703
Panama CityMilan
PTY Panama City Tocumen Intl - MXP Milan Malpensa
PTYMXP
Panama City Tocumen Intl
Thu 3/4
6:50 pm-1:30 pm
1 stop36h 40m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$703
Panama CityMilan
PTY Panama City Tocumen Intl - MXP Milan Malpensa
PTYMXP
Panama City Tocumen Intl
Wed 3/3
9:40 am-12:25 pm
2 stops20h 45m
Milan Malpensa
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$710
Panama CityRome
PTY Panama City Tocumen Intl - FCO Rome Fiumicino
PTYFCO
Panama City Tocumen Intl
Mon 9/28
10:20 pm-2:05 pm
1 stop32h 45m
Rome Fiumicino
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$734
Panama CityBologna
PTY Panama City Tocumen Intl - BLQ Bologna Guglielmo Marconi
PTYBLQ
Panama City Tocumen Intl
Fri 12/11
10:00 pm-9:55 am
1 stop29h 55m
Bologna Guglielmo Marconi
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$735
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Panama City to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
PTY-LIN
PTY-VCE
PTY-MXP
PTY-FCO
PTY-BLQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Italy
PTY-IT0
PTY-LIN
PTY-VCE
PTY-MXP
PTY-FCO
What is the cheapest month to book a flight from Panama City to Italy?
Currently, February is the cheapest month in which you can book a flight from Panama City to Italy (average of $784). Flying from Panama City to Italy in July is currently the most expensive (average of $1,103). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Panama City to Italy?
The best time to book flights from Panama City to Italy is 15 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Italy
Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated September 18, 2026.
Get a feel of what it's like to fly with Turkish Airlines,Air Europa, andCondor from Panama City to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Entertainment
7.5
Food
7.5
Boarding
7.3
Crew
7.8
Overall
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
MIA - IST
Comfort
7.3
Entertainment
7.5
Food
7.5
Boarding
7.3
Crew
7.8
Overall
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
MIA - IST
Comfort
7.3
Entertainment
7.5
Food
7.5
Boarding
7.3
Crew
7.8
Overall
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
MIA - IST
Comfort
7.3
Entertainment
7.5
Food
7.5
Boarding
7.3
Crew
7.8
Overall
7.4
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
MIA - IST
Related info for your journey
Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top regions
Alternative routes for Panama City to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Italy by cabin class
Find flights from Panama City to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Italy flights
Browse other Panama City and Italy flight options. Last updated on September 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 2 airlines flying from Panama City to Italy
Discover the top 2 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$679 | Average$1,062 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$752 | Average$860 | FlexibilityNo cancel fee | On-time77% |