$105+ Cheap flights from St. Louis (STL) to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Apr 23 — Apr 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Iowa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Iowa
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to IowaExplore the most affordable flight options available from St. Louis to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
Explore the most affordable flight options available from St. Louis to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:55 pm
STL
- DSM
1 stop6h 15m
Southwest
Tue 4/216:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 3/22![Southwest logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Fri 4/108:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/18![Frontier logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Tue 5/128:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Deal found 3/19![Frontier logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
- OMA
2 stops24h 53m
Frontier
Sat 5/98:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/19![Frontier logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Tue 5/128:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Deal found 3/19![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Wed 5/138:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/19![Frontier logo]()
$247
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:40 am
STL
- DSM
1 stop5h 50m
Southwest
Mon 4/275:25 am
DSM
- STL
1 stop4h 50m
Southwest
Deal found 3/23![Southwest logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Wed 5/138:19 pm
OMA
- STL
2 stops18h 29m
Frontier
Deal found 3/19![Frontier logo]()
$254
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:40 am
STL
- DSM
1 stop5h 50m
Southwest
Mon 4/205:25 am
DSM
- STL
1 stop4h 50m
Southwest
Deal found 3/23![Southwest logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
- OMA
2 stops24h 53m
Frontier
Wed 5/138:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/19![Frontier logo]()
$261
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:30 pm
STL
- DSM
2 stops7h 40m
Southwest
Fri 6/55:10 am
DSM
- STL
2 stops8h 40m
Southwest
Deal found 3/23![Southwest logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Mon 4/138:59 pm
OMA
- STL
2 stops33h 51m
Frontier
Deal found 3/18![Frontier logo]()
$279
Best flights from St. Louis to IowaDiscover carefully curated flight deals from St. Louis to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
Discover carefully curated flight deals from St. Louis to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:40 am
STL
- DSM
1 stop5h 50m
Southwest
Mon 4/275:25 am
DSM
- STL
1 stop4h 50m
Southwest
Deal found 3/23![Southwest logo]()
$250
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
STL
- DSM
1 stop4h 48m
Delta
Fri 4/310:28 am
DSM
- STL
1 stop6h 04m
Delta
Deal found 3/19![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/47:45 am
STL
- FOD
1 stop6h 16m
United Airlines
Wed 4/810:15 am
FOD
- STL
1 stop22h 10m
United Airlines
Deal found 3/19![United Airlines logo]()
$458
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:35 am
STL
- DSM
1 stop5h 50m
Southwest
Fri 6/54:40 pm
DSM
- STL
1 stop6h 10m
Southwest
Deal found 3/23![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:40 am
STL
- DSM
1 stop5h 50m
Southwest
Mon 4/205:25 am
DSM
- STL
1 stop4h 50m
Southwest
Deal found 3/23![Southwest logo]()
$256
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:10 am
STL
- DSM
2 stops7h 20m
Southwest
Sat 5/165:35 am
DSM
- STL
2 stops8h 00m
Southwest
Deal found 3/23![Southwest logo]()
$294
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Mon 5/1112:30 pm
OMA
- STL
1 stop7h 40m
Southwest
Deal found 3/22![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:35 am
STL
- DSM
1 stop5h 50m
Southwest
Wed 5/206:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 3/22![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:40 am
STL
- DSM
1 stop6h 05m
Southwest
Mon 4/274:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Deal found 3/21![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:40 pm
STL
- DSM
1 stop6h 25m
Southwest
Sun 5/315:20 am
DSM
- STL
1 stop4h 10m
Southwest
Deal found 3/21![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:25 am
STL
- DSM
1 stop6h 00m
Southwest
Sun 4/266:40 am
DSM
- STL
1 stop7h 00m
Southwest
Deal found 3/22![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Thu 4/237:20 pm
OMA
- STL
1 stop4h 30m
Southwest
Deal found 3/19![Southwest logo]()
$323
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:10 am
STL
- DSM
1 stop6h 20m
Southwest
Wed 4/86:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 3/19![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:20 am
STL
- DSM
1 stop6h 10m
Southwest
Thu 4/94:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Deal found 3/21![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Sat 5/27:05 am
OMA
- STL
1 stop6h 30m
Southwest
Deal found 3/22![Southwest logo]()
$331
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Sun 4/195:30 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/19![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:30 am
STL
- OMA
Nonstop1h 20m
Southwest
Fri 5/15:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/19![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:30 am
STL
- OMA
Nonstop1h 20m
Southwest
Sun 4/125:30 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/19![Southwest logo]()
$363
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:20 am
STL
- OMA
1 stop6h 35m
Southwest
Sun 5/243:20 pm
OMA
- STL
1 stop6h 35m
Southwest
Deal found 3/19![Southwest logo]()
$391
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:30 am
STL
- OMA
Nonstop1h 20m
Southwest
Sun 5/101:00 pm
OMA
- STL
1 stop4h 20m
Southwest
Deal found 3/19![Southwest logo]()
$391
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/182:35 pm
STL
- OMA
1 stop6h 15m
Southwest
Sat 4/256:50 am
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/21![Southwest logo]()
$402
This Expedia deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:20 pm
STL
- IRK
2 stops20h 25m
Multiple Airlines
Fri 4/101:40 pm
IRK
- STL
3 stops25h 25m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$10,804
Last-minute flights from St. Louis to IowaDiscover last-minute flight deals from St. Louis to Iowa. Data last updated March 24, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Iowa. Data last updated March 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Fri 4/108:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/18![Frontier logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Mon 4/138:59 pm
OMA
- STL
2 stops33h 51m
Frontier
Deal found 3/18![Frontier logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Sun 4/128:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/18![Frontier logo]()
$306
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:29 am
STL
- OMA
1 stop5h 04m
Delta
Sat 4/1112:18 pm
OMA
- STL
1 stop4h 50m
Delta
Deal found 3/18![Delta logo]()
$322
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:40 am
STL
- OMA
1 stop5h 55m
Southwest
Mon 4/135:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/19![Southwest logo]()
$323
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:55 pm
STL
- DSM
1 stop6h 15m
Southwest
Tue 4/216:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 3/22![Southwest logo]()
$213
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:05 am
STL
- OMA
1 stop4h 38m
American Airlines
Thu 4/237:35 pm
OMA
- STL
1 stop4h 11m
American Airlines
Deal found 3/19![American Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:40 am
STL
- DSM
1 stop6h 05m
Southwest
Sun 4/195:20 am
DSM
- STL
1 stop4h 10m
Southwest
Deal found 3/23![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:40 am
STL
- DSM
1 stop5h 50m
Southwest
Mon 4/205:25 am
DSM
- STL
1 stop4h 50m
Southwest
Deal found 3/23![Southwest logo]()
$256
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:25 am
STL
- DSM
1 stop6h 00m
Southwest
Sun 4/265:20 am
DSM
- STL
1 stop4h 10m
Southwest
Deal found 3/20![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:40 am
STL
- DSM
1 stop6h 05m
Southwest
Sun 4/265:20 am
DSM
- STL
1 stop4h 10m
Southwest
Deal found 3/20![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:40 am
STL
- DSM
1 stop5h 50m
Southwest
Mon 4/275:25 am
DSM
- STL
1 stop4h 50m
Southwest
Deal found 3/23![Southwest logo]()
$250
One-way flights from St. Louis to IowaSearch for one-way flight options from St. Louis to Iowa. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
Search for one-way flight options from St. Louis to Iowa. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:55 pm
STL
- DSM
1 stop5h 20m
Southwest
Deal found 3/23![Southwest logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 3/18![Frontier logo]()
$115
This Trip.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/21![Frontier logo]()
$120
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/23![Southwest logo]()
$124
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:40 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 3/23![Southwest logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:33 pm
STL
- OMA
2 stops25h 01m
Frontier
Deal found 3/18![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:50 am
STL
- DSM
2 stops13h 07m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/23![Frontier logo]()
$140
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:20 am
STL
- DSM
1 stop3h 56m
Delta
Deal found 3/20![Delta logo]()
$140
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
STL
- DSM
2 stops11h 02m
Delta
Deal found 3/20![Delta logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:50 am
STL
- DSM
2 stops12h 52m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/239:50 am
STL
- DSM
2 stops24h 20m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$148
Find flight deals from St. Louis to Iowa
Keep the following information in mind while searching for St. Louis to Iowa flight deals. Data was last updated March 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $213 (Southwest) |
One-way from | $105 (Southwest) |
Popular in | January |
Cheapest in | October |
Average price | $238 |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from St. Louis to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Sat 4/25
5:40 am-11:30 am
1 stop5h 50m
Des Moines
Mon 4/27
5:25 am-10:15 am
1 stop4h 50m
$250
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 6/3
5:35 am-11:25 am
1 stop5h 50m
Des Moines
Fri 6/5
4:40 pm-10:50 pm
1 stop6h 10m
$250
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Sat 4/18
5:40 am-11:30 am
1 stop5h 50m
Des Moines
Mon 4/20
5:25 am-10:15 am
1 stop4h 50m
$256
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Sat 5/9
6:10 am-1:30 pm
2 stops7h 20m
Des Moines
Sat 5/16
5:35 am-1:35 pm
2 stops8h 00m
$294
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Thu 5/7
9:40 pm-11:00 pm
Nonstop1h 20m
Omaha Eppley Airfield
Mon 5/11
12:30 pm-8:10 pm
1 stop7h 40m
$304
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 5/13
5:35 am-11:25 am
1 stop5h 50m
Des Moines
Wed 5/20
6:30 pm-11:10 pm
1 stop4h 40m
$317
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Mon 4/20
5:40 am-11:45 am
1 stop6h 05m
Des Moines
Mon 4/27
4:20 pm-10:45 pm
1 stop6h 25m
$317
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Fri 5/29
4:40 pm-11:05 pm
1 stop6h 25m
Des Moines
Sun 5/31
5:20 am-9:30 am
1 stop4h 10m
$321
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Sun 4/19
5:25 am-11:25 am
1 stop6h 00m
Des Moines
Sun 4/26
6:40 am-1:40 pm
1 stop7h 00m
$321
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Thu 4/16
9:40 pm-11:00 pm
Nonstop1h 20m
Omaha Eppley Airfield
Thu 4/23
7:20 pm-11:50 pm
1 stop4h 30m
$323
Showing 1-10 of 44 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from St. Louis with our price prediction graph.
STL-DSM
STL-OMA
STL-FOD
STL-IRK
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Iowa
STL-USIA
STL-DSM
STL-OMA
STL-FOD
STL-IRK
What is the cheapest time of day to fly from STL to IA?
Find hourly flight availability from St. Louis to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 24, 2026.
A simple way to save on the total cost of your ticket is to fly from St. Louis to Iowa in the afternoon. If you’re flexible enough to do this you can expect to save up to 36% on your trip compared to booking a flight in the morning.
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated March 24, 2026.
Read reviews from past customers who have flown Southwest and American Airlines from St. Louis to Iowa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for St. Louis to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Iowa by cabin class
Find flights from St. Louis to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Iowa flights
Browse other St. Louis and Iowa flight options. Last updated on March 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
St. Louis to Iowa flights
Consider these flights traveling from St. Louis to Iowa.
Top 2 airlines flying from St. Louis to Iowa
Discover the top 2 airlines that operate flights from St. Louis to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$309 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$142 | Average$333 | FlexibilityNo cancel fee | On-time71% |