Iowa

$105+ Cheap flights from St. Louis (STL) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Apr 23 — Apr 301
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Cheap flight deals from St. Louis to Iowa

Cheapest flights from St. Louis to Iowa
Explore the most affordable flight options available from St. Louis to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.

This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:55 pm
STL
-
DSM
1 stop6h 15m
Southwest
Tue 4/216:30 pm
DSM
-
STL
1 stop4h 40m
Southwest
Deal found 3/22$213
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
-
OMA
1 stop23h 58m
Frontier
Fri 4/108:59 pm
OMA
-
STL
1 stop12h 49m
Frontier
Deal found 3/18$223
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:08 pm
STL
-
OMA
1 stop23h 26m
Frontier
Tue 5/128:19 pm
OMA
-
STL
2 stops12h 36m
Frontier
Deal found 3/19$233
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
-
OMA
2 stops24h 53m
Frontier
Sat 5/98:19 pm
OMA
-
STL
1 stop23h 04m
Frontier
Deal found 3/19$238
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:08 pm
STL
-
OMA
1 stop23h 26m
Frontier
Tue 5/128:19 pm
OMA
-
STL
2 stops12h 36m
Frontier
Deal found 3/19$239
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:08 pm
STL
-
OMA
1 stop23h 26m
Frontier
Wed 5/138:19 pm
OMA
-
STL
1 stop23h 04m
Frontier
Deal found 3/19$247
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:40 am
STL
-
DSM
1 stop5h 50m
Southwest
Mon 4/275:25 am
DSM
-
STL
1 stop4h 50m
Southwest
Deal found 3/23$250
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:08 pm
STL
-
OMA
1 stop23h 26m
Frontier
Wed 5/138:19 pm
OMA
-
STL
2 stops18h 29m
Frontier
Deal found 3/19$254
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:40 am
STL
-
DSM
1 stop5h 50m
Southwest
Mon 4/205:25 am
DSM
-
STL
1 stop4h 50m
Southwest
Deal found 3/23$256
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
-
OMA
2 stops24h 53m
Frontier
Wed 5/138:19 pm
OMA
-
STL
1 stop23h 04m
Frontier
Deal found 3/19$261
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:30 pm
STL
-
DSM
2 stops7h 40m
Southwest
Fri 6/55:10 am
DSM
-
STL
2 stops8h 40m
Southwest
Deal found 3/23$261
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
-
OMA
1 stop23h 58m
Frontier
Mon 4/138:59 pm
OMA
-
STL
2 stops33h 51m
Frontier
Deal found 3/18$279

Find flight deals from St. Louis to Iowa

Keep the following information in mind while searching for St. Louis to Iowa flight deals. Data was last updated March 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$213
(Southwest)

One-way from

$105
(Southwest)

Popular in

January

Cheapest in

October

Average price

$238

Good one-way deal

$194 or less
Provider with most accurate pricing for Lambert-St Louis-Des Moines flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-Des Moines flights.
From Lambert-St Louis to Iowa
One-way flight from Lambert-St Louis to Iowa
Highest demand for flights based on searches. 39% potential increase in price ($235 potential increase over avg. RT price).
Cheapest flight prices on average. 9% potential price decrease ($32 potential savings vs. average RT price).
Average for round-trip flights in March 2026
Price to beat on a one-way flight from Lambert-St Louis to Iowa.

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from St. Louis to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 4/25

5:40 am-11:30 am

1 stop5h 50m

Des Moines

Mon 4/27

5:25 am-10:15 am

1 stop4h 50m

$250

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 6/3

5:35 am-11:25 am

1 stop5h 50m

Des Moines

Fri 6/5

4:40 pm-10:50 pm

1 stop6h 10m

$250

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 4/18

5:40 am-11:30 am

1 stop5h 50m

Des Moines

Mon 4/20

5:25 am-10:15 am

1 stop4h 50m

$256

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 5/9

6:10 am-1:30 pm

2 stops7h 20m

Des Moines

Sat 5/16

5:35 am-1:35 pm

2 stops8h 00m

$294

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Thu 5/7

9:40 pm-11:00 pm

Nonstop1h 20m

Omaha Eppley Airfield

Mon 5/11

12:30 pm-8:10 pm

1 stop7h 40m

$304

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 5/13

5:35 am-11:25 am

1 stop5h 50m

Des Moines

Wed 5/20

6:30 pm-11:10 pm

1 stop4h 40m

$317

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Mon 4/20

5:40 am-11:45 am

1 stop6h 05m

Des Moines

Mon 4/27

4:20 pm-10:45 pm

1 stop6h 25m

$317

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 5/29

4:40 pm-11:05 pm

1 stop6h 25m

Des Moines

Sun 5/31

5:20 am-9:30 am

1 stop4h 10m

$321

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sun 4/19

5:25 am-11:25 am

1 stop6h 00m

Des Moines

Sun 4/26

6:40 am-1:40 pm

1 stop7h 00m

$321

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Thu 4/16

9:40 pm-11:00 pm

Nonstop1h 20m

Omaha Eppley Airfield

Thu 4/23

7:20 pm-11:50 pm

1 stop4h 30m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 44 resultsSorted by cheapest first
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Best time to book a flight from St. Louis to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Iowa

What is the cheapest time of day to fly from STL to IA?

Find hourly flight availability from St. Louis to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 24, 2026.

A simple way to save on the total cost of your ticket is to fly from St. Louis to Iowa in the afternoon. If you’re flexible enough to do this you can expect to save up to 36% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated March 24, 2026.
Read reviews from past customers who have flown Southwest and American Airlines from St. Louis to Iowa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from St. Louis to Iowa?

    Most people fly from Lambert-St Louis (STL) if they book a flight from St. Louis to Iowa. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • How popular is this St. Louis to Iowa flight route?

  • How long is the flight from St. Louis to Iowa?

    Departing from St. Louis to Iowa will take you 5h 50m. Airlines will cover a distance of 259 mi. This flight may include one or multiple stops.

  • What are the most popular routes from St. Louis to Iowa?

  • What are the cheapest flights from St. Louis to Iowa?

    Looking for the cheapest flight from St. Louis to Iowa? While on average our users pay $194, our data indicates the cheapest price to be $175. The most popular route (Lambert-St Louis - Omaha Eppley Airfield), is priced around $277.

  • Can I find deals for flights from St. Louis to Iowa that include hotel bookings?

    Yes. In addition to deals on St. Louis to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Iowa.

  • Can I find deals for business class flights from St. Louis to Iowa?

    Yes. Cheapflights offers flight deals from St. Louis to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for St. Louis to Iowa

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from St. Louis to Iowa

Discover the top 2 airlines that operate flights from St. Louis to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$77Average$309FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$142Average$333FlexibilityNo cancel feeOn-time71%

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