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$79+ Cheap flights from Spartanburg, SC to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Spartanburg to Iowa

Keep the following information in mind while searching for Spartanburg to Iowa flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$204
(Kiwi.com)

One-way from

$79
(Kiwi.com)

Popular in

December

Cheapest in

March

Average price

$421
Provider with most accurate pricing for Charlotte Douglas-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Des Moines flights.
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From Spartanburg to Iowa
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One-way flight from Spartanburg to Iowa
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Highest demand for flights based on searches. 7% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Spartanburg to Iowa

Cheapest flights from Spartanburg to Iowa
Explore the most affordable flight options available from Spartanburg to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:49 pmCLT - DSM
1 stop26h 14mMultiple Airlines
Thu 12/112:56 pmDSM - CLT
1 stop8h 03mMultiple Airlines
Deal found 10/29$204
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:49 amCLT - CID
1 stop9h 54mMultiple Airlines
Mon 11/246:38 pmCID - CLT
2 stops21h 12mMultiple Airlines
Deal found 10/29$212
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:59 pmCLT - CID
1 stop24h 44mMultiple Airlines
Mon 11/246:38 pmCID - CLT
2 stops21h 12mMultiple Airlines
Deal found 10/29$214
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/253:11 pmCLT - DSM
1 stop9h 13mMultiple Airlines
Mon 12/16:53 pmDSM - CLT
1 stop18h 13mMultiple Airlines
Deal found 10/28$232
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:09 pmCLT - DSM
1 stop23h 31mMultiple Airlines
Mon 11/246:40 amDSM - CLT
1 stop15h 28mMultiple Airlines
Deal found 10/29$233
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:56 amCLT - MLI
1 stop23h 35mMultiple Airlines
Mon 12/18:36 amMLI - CLT
1 stop24h 14mMultiple Airlines
Deal found 10/27$236
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:45 amCLT - CID
1 stop24h 42mMultiple Airlines
Wed 12/1011:17 amCID - CLT
1 stop25h 24mMultiple Airlines
Deal found 10/30$259
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:56 amCLT - DSM
1 stop27h 10mMultiple Airlines
Mon 12/16:53 pmDSM - CLT
1 stop18h 13mMultiple Airlines
Deal found 10/27$264
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:56 amCLT - DSM
1 stop29h 42mMultiple Airlines
Mon 11/246:40 amDSM - CLT
1 stop15h 28mMultiple Airlines
Deal found 10/29$267
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:47 pmCLT - MLI
1 stop18h 29mMultiple Airlines
Mon 12/18:36 amMLI - CLT
1 stop24h 14mMultiple Airlines
Deal found 10/27$268
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amCLT - DSM
1 stop7h 55mMultiple Airlines
Mon 12/16:53 pmDSM - CLT
1 stop18h 13mMultiple Airlines
Deal found 10/27$273
This Booking.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:43 pmCLT - DSM
1 stop13h 36mFrontier
Tue 12/3011:14 amDSM - CLT
1 stop8h 15mFrontier
Deal found 10/30$279

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Spartanburg to Iowa that are best for you.

Fly from

Spartanburg

Fly to

Iowa

Route

Depart

Return

Price

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

Thu 11/20

5:59 pm-5:43 pm

1 stop24h 44m

Cedar Rapids

Mon 11/24

6:38 pm-4:50 pm

2 stops21h 12m

$223

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 11/25

3:11 pm-11:24 pm

1 stop9h 13m

Des Moines

Mon 12/1

6:53 pm-2:06 pm

1 stop18h 13m

$232

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 12/4

3:42 pm-12:55 pm

2 stops22h 13m

Des Moines

Thu 12/11

2:56 pm-11:59 pm

1 stop8h 03m

$246

CharlotteMoline

CLT - MLI

CLTMLI

Charlotte Douglas

Mon 11/24

2:47 pm-8:16 am

1 stop18h 29m

Moline Quad-City

Mon 12/1

8:36 am-9:50 am

1 stop24h 14m

$268

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

Fri 12/12

8:54 am-5:07 pm

1 stop9h 13m

Cedar Rapids

Sat 1/10

10:52 am-1:03 pm

2 stops25h 11m

$294

CharlotteMoline

CLT - MLI

CLTMLI

Charlotte Douglas

Tue 11/11

3:30 pm-4:56 pm

Nonstop2h 26m

Moline Quad-City

Sat 11/15

5:43 pm-9:01 pm

Nonstop2h 18m

$319

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 12/23

9:00 am-11:10 pm

1 stop15h 10m

Des Moines

Tue 12/30

3:45 pm-11:29 pm

1 stop6h 44m

$320

CharlotteMoline

CLT - MLI

CLTMLI

Charlotte Douglas

Sat 11/8

10:00 am-4:37 pm

2 stops7h 37m

Moline Quad-City

Wed 11/12

3:55 pm-9:20 pm

1 stop4h 25m

$324

CharlotteMoline

CLT - MLI

CLTMLI

Charlotte Douglas

Fri 11/7

7:35 pm-9:07 pm

Nonstop2h 32m

Moline Quad-City

Tue 11/11

5:22 pm-8:40 pm

Nonstop2h 18m

$328

CharlotteMoline

CLT - MLI

CLTMLI

Charlotte Douglas

Tue 11/25

3:18 pm-4:42 pm

Nonstop2h 24m

Moline Quad-City

Mon 12/1

5:37 pm-8:55 pm

Nonstop2h 18m

$328

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from Spartanburg to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Iowa

What is the cheapest month to book a flight from Spartanburg to Iowa?

Currently, November is the cheapest month in which you can book a flight from Spartanburg to Iowa (average of $157). Flying from Spartanburg to Iowa in December is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to IA?

Find hourly flight availability from Spartanburg to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 17% on flights from Spartanburg to Iowa by exploring options for tickets in the evening.

What is the cheapest day to fly from Spartanburg to Iowa?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Iowa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to Iowa flight should consider departing on Saturday afternoons when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Spartanburg to Iowa, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Spartanburg to Iowa?

    A quick flight from Spartanburg to Iowa can take about 2h 26m. American Airlines provides one of the quickest options available for as low as $319. Spartanburg and Iowa are separated by a distance of 672 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Spartanburg to Iowa one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $79. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from Spartanburg to Iowa for a low price.

  • What are the most popular routes from Spartanburg to Iowa?

    When deciding which route to take from Spartanburg to Iowa consider Charlotte Douglas - Omaha Eppley Airfield, Charlotte Douglas - Des Moines or Charlotte Douglas - Cedar Rapids as they are the most popular.

  • What are the cheapest flights from Spartanburg to Iowa?

    On average you can expect to pay $483 for a flight from Spartanburg to Iowa. The cheapest flight overall is $439 while the most popular route, (Charlotte Douglas - Omaha Eppley Airfield) is currently priced at $354.

  • Can I find deals for flights from Spartanburg to Iowa that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Iowa.

  • Can I find deals for business class flights from Spartanburg to Iowa?

    Yes. Cheapflights offers flight deals from Spartanburg to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Iowa?

    Currently, November is the cheapest month in which you can book a flight from Spartanburg to Iowa (average of $157). Flying from Spartanburg to Iowa in December is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Spartanburg to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Spartanburg to Iowa

Discover the top 3 airlines that operate flights from Spartanburg to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$338FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$423FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$421FlexibilityNo cancel feeOn-time71%

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