HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$156+ Cheap flights from Roanoke (ROA) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — DSM
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Roanoke to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Roanoke to Iowa

Keep the following information in mind while searching for Roanoke to Iowa flight deals. Data was last updated January 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(Delta)

One-way from

$156
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$403
Provider with most accurate pricing for Roanoke-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Des Moines flights.
Search Deals
From Roanoke to Iowa
Search Deals
One-way flight from Roanoke to Iowa
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Find flight deals from Roanoke to Iowa

Cheapest flights from Roanoke to Iowa
Explore the most affordable flight options available from Roanoke to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 amROA - MLI
1 stop5h 26mDelta
Sat 5/305:00 pmMLI - ROA
1 stop5h 49mDelta
Deal found 1/5$269
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/285:14 pmROA - DSM
1 stop6h 54mAmerican Airlines
Sat 1/315:00 pmDSM - ROA
1 stop5h 42mAmerican Airlines
Deal found 1/6$269
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/236:00 amROA - OMA
1 stop5h 05mDelta
Mon 1/264:35 pmOMA - ROA
1 stop5h 31mDelta
Deal found 1/5$274
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/286:00 amROA - DSM
1 stop5h 41mDelta
Sat 1/316:24 amDSM - ROA
2 stops7h 43mDelta
Deal found 1/6$274
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/203:39 pmROA - CID
1 stop4h 31mUnited Airlines
Sat 1/2411:32 amCID - ROA
1 stop4h 31mUnited Airlines
Deal found 1/6$279
This United Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/203:39 pmROA - DSM
1 stop7h 11mUnited Airlines
Sat 1/243:35 pmDSM - ROA
1 stop4h 36mUnited Airlines
Deal found 1/4$279
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/282:55 pmROA - DSM
2 stops7h 55mUnited Airlines
Sat 1/317:50 amDSM - ROA
2 stops10h 41mUnited Airlines
Deal found 1/6$280
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/231:56 pmROA - OMA
2 stops10h 37mAmerican Airlines
Sun 1/253:07 pmOMA - ROA
1 stop5h 08mAmerican Airlines
Deal found 1/6$284
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/205:14 pmROA - CID
1 stop6h 51mAmerican Airlines
Sat 1/2410:08 amCID - ROA
2 stops10h 07mAmerican Airlines
Deal found 1/6$284
This Delta deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/206:00 amROA - DSM
1 stop5h 41mDelta
Sat 1/246:24 amDSM - ROA
2 stops7h 43mDelta
Deal found 1/4$284
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/231:56 pmROA - OMA
2 stops10h 37mAmerican Airlines
Mon 1/267:00 amOMA - ROA
2 stops8h 10mAmerican Airlines
Deal found 1/5$285
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:00 amROA - MLI
1 stop5h 26mDelta
Sun 5/315:00 pmMLI - ROA
1 stop5h 49mDelta
Deal found 1/5$304

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Roanoke to Iowa that are best for you.

Fly from

Roanoke

Fly to

Iowa

Route

Depart

Return

Price

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Fri 5/22

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Sun 5/31

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Wed 1/28

5:14 pm-11:08 pm

1 stop6h 54m

Des Moines

Sat 1/31

5:00 pm-11:42 pm

1 stop5h 42m

$269

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Tue 5/26

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Sat 5/30

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Fri 5/22

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Mon 6/1

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Tue 5/26

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Mon 6/1

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Sat 5/23

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Fri 5/29

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Wed 5/20

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Mon 6/1

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Sat 5/23

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Sat 5/30

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Wed 5/20

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Tue 6/2

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Tue 5/26

6:00 am-10:26 am

1 stop5h 26m

Moline Quad-City

Sun 5/31

5:00 pm-11:49 pm

1 stop5h 49m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/5

Showing 1-10 of 32 results
1
2
3
4

Best time to book a flight from Roanoke to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Iowa

What is the cheapest month to book a flight from Roanoke to Iowa?

Currently, May is the cheapest month in which you can book a flight from Roanoke to Iowa (average of $209). Flying from Roanoke to Iowa in December is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated January 6, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Roanoke to Iowa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,132 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
United Airlines
7.4
Good
9,132 reviews
United Airlines
7.4
Good
9,132 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
American Airlines
7.2
Good
11,084 reviews
United Airlines
7.4
Good
9,132 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Iowa?

    Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly out of when you book flights from Roanoke to Iowa.

  • How long is the flight from Roanoke to Iowa?

    For as low as $279, Delta can have you in Iowa from Roanoke in 4h 31m. There are 698 mi between Roanoke and Iowa. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to Iowa?

    The most popular route from Roanoke to Iowa is Roanoke - Omaha Eppley Airfield. You may also consider Roanoke - Cedar Rapids or Roanoke - Moline Quad-City.

  • Can I find deals for flights from Roanoke to Iowa that include hotel bookings?

    Yes. In addition to deals on Roanoke to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Iowa.

  • Can I find deals for business class flights from Roanoke to Iowa?

    Yes. Cheapflights offers flight deals from Roanoke to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Iowa?

    Currently, May is the cheapest month in which you can book a flight from Roanoke to Iowa (average of $209). Flying from Roanoke to Iowa in December is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Roanoke to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Dulles Intl to Miami flights
Reagan-National to Miami flights
Dulles Intl to Las Vegas flights
Dulles Intl to Orlando flights
Reagan-National to Orlando flights
Dulles Intl to Dallas/Fort Worth flights
Dulles Intl to Fort Lauderdale flights
Reagan-National to Los Angeles flights
Dulles Intl to Tampa flights
Reagan-National to Las Vegas flights
Reagan-National to Fort Lauderdale flights
Dulles Intl to Los Angeles flights
Dulles Intl to Sky Harbor Intl flights
Reagan-National to Dallas/Fort Worth flights
Dulles Intl to Denver flights
Reagan-National to Hobby flights
Reagan-National to Seattle flights
Dulles Intl to New Orleans flights
Reagan-National to Tampa flights
Raleigh to Miami flights
Dulles Intl to Atlanta flights
Raleigh to John F Kennedy Intl flights
Dulles Intl to Seattle flights
Dulles Intl to O'Hare Intl flights
Dulles Intl to Salt Lake City flights
Raleigh to Las Vegas flights
Reagan-National to Sky Harbor Intl flights
Reagan-National to San Francisco flights
Dulles Intl to Hobby flights
Reagan-National to O'Hare Intl flights
Dulles Intl to Austin flights
Dulles Intl to San Francisco flights
Reagan-National to Atlanta flights
Reagan-National to Denver flights
Reagan-National to West Palm Beach flights
Reagan-National to Salt Lake City flights
Reagan-National to New Orleans flights
Raleigh to LaGuardia flights
Raleigh to Orlando flights
Reagan-National to George Bush Intcntl flights
Dulles Intl to George Bush Intcntl flights
Raleigh to Dallas/Fort Worth flights
Reagan-National to Austin flights
Dulles Intl to Boston flights
Dulles Intl to Fort Myers flights
Raleigh to Fort Lauderdale flights
Reagan-National to Nashville flights
Raleigh to Denver flights
Dulles Intl to Nashville flights
Raleigh to Newark flights

Top 2 airlines flying from Roanoke to Iowa

Discover the top 2 airlines that operate flights from Roanoke to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$353FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$381FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.