$208+ Cheap flights from Roanoke (ROA) to Iowa
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — DSM
Oct 4 — Oct 111
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Iowa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Roanoke to IowaExplore the most affordable flight options available from Roanoke to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
Explore the most affordable flight options available from Roanoke to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop6h 15m
Sat 11/74:00 pm -
1 stop4h 57m
Deal found 9/2![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:38 pm -
1 stop5h 28m
Tue 11/105:40 pm -
1 stop5h 39m
Deal found 9/2![Delta logo]()
$310
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 am -
1 stop6h 51m
Mon 11/96:03 am -
2 stops7h 12m
Deal found 9/2![United Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:47 pm -
1 stop7h 18m
Mon 10/54:19 pm -
1 stop6h 25m
Deal found 9/1![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:38 pm -
1 stop5h 28m
Sun 11/85:43 pm -
1 stop5h 44m
Deal found 9/2![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop5h 46m
Wed 10/76:54 pm -
1 stop4h 33m
Deal found 8/31![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:09 pm -
2 stops9h 06m
Mon 11/98:37 am -
2 stops10h 19m
Deal found 9/2![American Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:29 pm -
2 stops9h 44m
Mon 10/55:34 pm -
1 stop5h 10m
Deal found 8/30![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:27 pm -
2 stops9h 37m
Tue 10/69:26 am -
1 stop5h 52m
Deal found 9/1![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:27 pm -
2 stops9h 37m
Wed 10/79:26 am -
1 stop5h 52m
Deal found 8/31![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:47 pm -
1 stop7h 30m
Tue 9/225:00 am -
2 stops9h 01m
Deal found 8/31![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:51 pm -
1 stop6h 13m
Mon 9/213:11 pm -
1 stop4h 43m
Deal found 9/2![United Airlines logo]()
$349
Best flights from Roanoke to IowaDiscover carefully curated flight deals from Roanoke to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
Discover carefully curated flight deals from Roanoke to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:38 pm -
1 stop5h 28m
Sun 11/85:43 pm -
1 stop5h 44m
Deal found 9/2![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:07 pm -
1 stop5h 09m
Mon 10/55:34 pm -
1 stop5h 10m
Deal found 8/30![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:51 pm -
1 stop6h 13m
Mon 9/213:11 pm -
1 stop4h 43m
Deal found 9/2![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:47 pm -
1 stop7h 17m
Tue 10/69:26 am -
1 stop5h 52m
Deal found 9/4![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:38 pm -
1 stop4h 55m
Fri 10/236:54 pm -
1 stop4h 33m
Deal found 8/31![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
2 stops7h 19m
Mon 10/53:11 pm -
2 stops7h 33m
Deal found 9/1![United Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:27 pm -
2 stops9h 37m
Wed 10/79:26 am -
1 stop5h 52m
Deal found 8/31![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:47 pm -
1 stop7h 30m
Tue 9/225:00 am -
2 stops9h 01m
Deal found 9/1![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:49 am -
1 stop6h 25m
Sat 10/243:13 pm -
1 stop6h 46m
Deal found 9/3![United Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:00 pm -
2 stops9h 32m
Sat 1/91:11 pm -
1 stop6h 54m
Deal found 9/1![United Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:01 pm -
1 stop6h 37m
Tue 11/103:15 pm -
2 stops7h 29m
Deal found 9/2![United Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/610:35 am -
1 stop4h 09m
Tue 2/92:31 pm -
1 stop5h 34m
Deal found 9/1![United Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:57 pm -
2 stops11h 08m
Mon 10/54:19 pm -
1 stop4h 34m
Deal found 9/1![American Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:35 am -
1 stop4h 44m
Wed 12/98:00 am -
1 stop4h 23m
Deal found 8/30![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/62:18 pm -
1 stop5h 55m
Wed 2/108:00 am -
1 stop4h 30m
Deal found 8/30![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:51 pm -
1 stop5h 51m
Mon 9/213:39 pm -
1 stop4h 15m
Deal found 9/2![United Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:17 am -
2 stops12h 03m
Wed 10/217:04 am -
2 stops9h 14m
Deal found 9/4![American Airlines logo]()
$999
Last-minute flights from Roanoke to IowaDiscover last-minute flight deals from Roanoke to Iowa. Data last updated September 4, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Iowa. Data last updated September 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:46 pm -
1 stop6h 40m
Mon 9/146:54 pm -
1 stop4h 05m
Deal found 9/1![Delta logo]()
$392
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:47 pm -
1 stop7h 30m
Tue 9/225:00 am -
2 stops9h 01m
Deal found 8/31![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:51 pm -
1 stop6h 13m
Mon 9/213:11 pm -
1 stop4h 43m
Deal found 9/2![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop5h 46m
Wed 10/76:54 pm -
1 stop4h 33m
Deal found 8/31![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:27 pm -
2 stops9h 37m
Tue 10/69:26 am -
1 stop5h 52m
Deal found 9/1![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:27 pm -
2 stops9h 37m
Wed 10/79:26 am -
1 stop5h 52m
Deal found 8/31![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:47 pm -
1 stop7h 18m
Mon 10/54:19 pm -
1 stop6h 25m
Deal found 9/1![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
2 stops7h 19m
Mon 10/53:11 pm -
2 stops7h 33m
Deal found 9/1![United Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:07 pm -
1 stop5h 09m
Mon 10/55:34 pm -
1 stop5h 10m
Deal found 8/30![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:10 pm -
1 stop7h 28m
Sun 10/116:00 am -
1 stop6h 48m
Deal found 9/2![American Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:38 pm -
1 stop4h 55m
Fri 10/236:54 pm -
1 stop4h 33m
Deal found 9/1![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:49 am -
1 stop6h 25m
Sat 10/243:13 pm -
1 stop6h 46m
Deal found 9/3![United Airlines logo]()
$381
One-way flights from Roanoke to IowaSearch for one-way flight options from Roanoke to Iowa. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
Search for one-way flight options from Roanoke to Iowa. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:59 pm -
3 stops45h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:59 pm -
1 stop24h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Allegiant Air logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:42 pm -
1 stop19h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Allegiant Air logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:12 am -
3 stops52h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$247
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:32 pm -
1 stop4h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Delta logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:10 pm -
1 stop6h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
2 stops9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![United Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:42 pm -
3 stops33h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:41 pm -
3 stops42h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Allegiant Air logo]()
$487
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:47 pm -
1 stop7h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![American Airlines logo]()
$605
Find flight deals from Roanoke to Iowa
Keep the following information in mind while searching for Roanoke to Iowa flight deals. Data was last updated September 4, 2026.
Round-trip from | $301 (Delta) |
|---|---|
One-way from | $208 (Kiwi.com) |
Popular in | August |
Cheapest in | September |
Average price | $298 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
Use the filters below to find and compare flights from Roanoke to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Fri 10/2
3:59 pm-12:39 pm
3 stops45h 40m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$208
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Thu 10/1
1:42 pm-7:54 am
1 stop19h 12m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$217
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Mon 9/28
10:12 am-1:52 pm
3 stops52h 40m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$248
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Sat 10/3
11:12 am-3:15 pm
1 stop5h 03m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
RoanokeCedar Rapids
ROA Roanoke - CID Cedar Rapids
ROACID
Roanoke
Thu 10/8
6:10 pm-11:58 pm
1 stop6h 48m
Cedar Rapids
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Mon 9/28
6:32 pm-10:26 pm
1 stop4h 54m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Tue 9/29
6:40 pm-10:26 pm
1 stop4h 46m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Thu 10/1
3:27 pm-12:04 am
2 stops9h 37m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$279
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Thu 10/1
1:42 pm-3:26 pm
3 stops50h 44m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$290
Quickest round-trip
RoanokeDes Moines
ROA Roanoke - DSM Des Moines
ROADSM
Roanoke
Sun 10/4
6:49 am-10:30 am
1 stop4h 41m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$300
Showing 1-10 of 30 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Roanoke with our price prediction graph.
ROA-DSM
ROA-CID
ROA-LSE
ROA-OMA
ROA-MLI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Iowa
ROA-USIA
ROA-DSM
ROA-CID
ROA-LSE
ROA-OMA
How much does it cost to fly round-trip from Roanoke to Iowa?
Airfare is typical for this route at the moment.
Roanoke to Iowa flights typically cost between $298 and $353 in September.The cheapest round-trip price found within the last 5 days was $319 on Delta (Sep 30-Oct 7).
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated September 4, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Roanoke to Iowa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Food
6.7
Crew
8.1
Overall
7.4
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Entertainment
7.1
Food
6.7
Crew
8.1
Overall
7.4
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Boarding
7.7
Entertainment
7.1
Food
6.7
Crew
8.1
Overall
7.4
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Roanoke to Iowa
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Complete your trip
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Roanoke and Iowa flights
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Roanoke to Iowa flights
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Top 2 airlines flying from Roanoke to Iowa
Discover the top 2 airlines that operate flights from Roanoke to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$274 | Average$374 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$318 | Average$767 | FlexibilityNo cancel fee | On-time69% |