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$132+ Cheap flights from Roanoke (ROA) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — DSM
Dec 22 — Dec 291
Mon 12/22
Mon 12/29
1 adult, Economy
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Find flight deals from Roanoke to Iowa

Cheapest flights from Roanoke to Iowa
Explore the most affordable flight options available from Roanoke to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 22, 2025.

This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:09 amROA - DSM
1 stop7h 20mAmerican Airlines
Sun 12/144:07 pmDSM - ROA
1 stop5h 46mAmerican Airlines
Deal found 11/21$279
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:00 amROA - DSM
1 stop5h 38mDelta
Sun 12/143:17 pmDSM - ROA
1 stop7h 02mDelta
Deal found 11/20$304
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:45 amROA - MLI
1 stop4h 30mUnited Airlines
Tue 12/91:00 pmMLI - ROA
1 stop6h 45mUnited Airlines
Deal found 11/20$349
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:59 pmROA - OMA
1 stop4h 57mDelta
Wed 11/265:55 pmOMA - ROA
1 stop5h 20mDelta
Deal found 11/21$369
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:02 amROA - DSM
1 stop7h 20mAmerican Airlines
Sun 11/234:03 pmDSM - ROA
1 stop5h 48mAmerican Airlines
Deal found 11/21$369
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:38 pmROA - OMA
1 stop5h 19mUnited Airlines
Wed 11/266:00 amOMA - ROA
2 stops11h 43mUnited Airlines
Deal found 11/21$374
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:20 amROA - DSM
2 stops8h 59mUnited Airlines
Sun 11/2311:26 amDSM - ROA
1 stop4h 30mUnited Airlines
Deal found 11/21$374
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:40 amROA - MLI
1 stop6h 33mUnited Airlines
Fri 12/261:00 pmMLI - ROA
1 stop6h 58mUnited Airlines
Deal found 11/21$379
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:55 pmROA - DSM
2 stops9h 49mUnited Airlines
Sun 12/145:45 amDSM - ROA
2 stops12h 11mUnited Airlines
Deal found 11/21$419
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:40 pmROA - CID
1 stop4h 39mUnited Airlines
Tue 12/92:52 pmCID - ROA
1 stop4h 53mUnited Airlines
Deal found 11/20$454
This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:45 amROA - MLI
1 stop4h 30mUnited Airlines
Mon 12/83:56 pmMLI - ROA
1 stop17h 10mUnited Airlines
Deal found 11/19$463
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:45 amROA - MLI
1 stop6h 05mUnited Airlines
Sat 1/173:45 pmMLI - ROA
2 stops21h 24mUnited Airlines
Deal found 11/21$492

Cheap flight deals from Roanoke to Iowa

Keep the following information in mind while searching for Roanoke to Iowa flight deals. Data was last updated November 22, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$132
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$348
Provider with most accurate pricing for Roanoke-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Des Moines flights.
Search Deals
From Roanoke to Iowa
Search Deals
One-way flight from Roanoke to Iowa
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($33 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 22, 2025.
Use the filters below to find and compare flights from Roanoke to Iowa that are best for you.

Fly from

Roanoke

Fly to

Iowa

Route

Depart

Return

Price

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Tue 2/3

6:00 am-10:38 am

1 stop5h 38m

Des Moines

Sat 2/7

1:03 pm-7:21 pm

1 stop5h 18m

$249

RoanokeCedar Rapids

ROA - CID

ROACID

Roanoke

Tue 2/10

11:24 am-10:45 pm

2 stops12h 21m

Cedar Rapids

Sat 2/14

4:17 pm-11:49 pm

2 stops6h 32m

$259

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Sat 1/24

5:25 pm-10:28 pm

1 stop6h 03m

Moline Quad-City

Wed 1/28

5:06 pm-12:04 am

1 stop5h 58m

$264

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Fri 12/12

10:09 am-4:29 pm

1 stop7h 20m

Des Moines

Sun 12/14

4:07 pm-10:53 pm

1 stop5h 46m

$279

RoanokeOmaha

ROA - OMA

ROAOMA

Roanoke

Sat 1/17

6:00 am-11:20 am

1 stop6h 20m

Omaha Eppley Airfield

Wed 1/21

4:35 pm-11:06 pm

1 stop5h 31m

$294

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Fri 12/12

6:00 am-10:38 am

1 stop5h 38m

Des Moines

Sun 12/14

3:17 pm-11:19 pm

1 stop7h 02m

$304

RoanokeCedar Rapids

ROA - CID

ROACID

Roanoke

Tue 2/10

5:14 pm-11:05 pm

1 stop6h 51m

Cedar Rapids

Sat 2/14

6:20 pm-11:44 pm

1 stop4h 24m

$319

RoanokeOmaha

ROA - OMA

ROAOMA

Roanoke

Sat 1/17

8:00 am-4:50 pm

2 stops9h 50m

Omaha Eppley Airfield

Wed 1/21

6:10 am-12:09 pm

1 stop4h 59m

$324

RoanokeOmaha

ROA - OMA

ROAOMA

Roanoke

Sat 1/17

2:55 pm-11:07 pm

2 stops9h 12m

Omaha Eppley Airfield

Wed 1/21

9:00 am-7:31 pm

2 stops9h 31m

$329

RoanokeMoline

ROA - MLI

ROAMLI

Roanoke

Sat 12/6

6:45 am-11:50 am

1 stop6h 05m

Moline Quad-City

Wed 12/10

1:00 pm-8:45 pm

1 stop6h 45m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 33 results
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Best time to book a flight from Roanoke to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Iowa

What is the cheapest month to book a flight from Roanoke to Iowa?

Currently, May is the cheapest month in which you can book a flight from Roanoke to Iowa (average of $209). Flying from Roanoke to Iowa in December is currently the most expensive (average of $265). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to IA?

Find hourly flight availability from Roanoke to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 22, 2025.

It’s optimal to fly from Roanoke to Iowa in the evening. By choosing this option you can save up to 33% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated November 22, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from Roanoke to Iowa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,035 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,035 reviews
United Airlines
7.4
Good
9,035 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,048 reviews
United Airlines
7.4
Good
9,035 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Iowa?

    Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly out of when you book flights from Roanoke to Iowa.

  • How long is the flight from Roanoke to Iowa?

    For as low as $249, Delta can have you in Iowa from Roanoke in 5h 38m. There are 784 mi between Roanoke and Iowa. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Roanoke to Iowa one-way?

    $132 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $239 and $244, respectively.

  • What are the most popular routes from Roanoke to Iowa?

    The most popular route from Roanoke to Iowa is Roanoke - Moline Quad-City. You may also consider Roanoke - Des Moines or Roanoke - Cedar Rapids.

  • Can I find deals for flights from Roanoke to Iowa that include hotel bookings?

    Yes. In addition to deals on Roanoke to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Iowa.

  • Can I find deals for business class flights from Roanoke to Iowa?

    Yes. Cheapflights offers flight deals from Roanoke to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Iowa?

    Currently, May is the cheapest month in which you can book a flight from Roanoke to Iowa (average of $209). Flying from Roanoke to Iowa in December is currently the most expensive (average of $265). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Roanoke to Iowa

Discover the top 2 airlines that operate flights from Roanoke to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$381FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$356FlexibilityNo cancel feeOn-time69%

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