How long is the flight from Santa Ana, California to Indianapolis?

A quick flight from Santa Ana, California to Indianapolis can take about 12h 19m. Delta provides one of the quickest options available for as low as $274. Santa Ana, California and Indianapolis are separated by a distance of 1787 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Santa Ana, California to Indianapolis round-trip?

According to our current data, Spirit Airlines ($158), American Airlines ($286), and Delta ($286) offers the cheapest pricing from Santa Ana, California to Indianapolis. Spirit Airlines is currently priced 63% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Santa Ana, California to Indianapolis one-way?

To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $139. Delta flights start at $143 while deals on United Airlines start at $153 one-way.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

What are the most popular airlines that fly from Santa Ana, California to Indianapolis?

Consider American Airlines, Southwest or United Airlines when booking your flight. These represent the most popular airlines when flying from Santa Ana, California to Indianapolis.

Most accurate provider : When it comes to deals on Santa Ana, California-Indianapolis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Ana, California-Indianapolis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Indianapolis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Santa Ana, California-Indianapolis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Santa Ana to Indianapolis that include hotel bookings?

Yes. In addition to deals on Santa Ana to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to Indianapolis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Indianapolis.

Can I find deals for business class flights from Santa Ana to Indianapolis?

Yes. Cheapflights offers flight deals from Santa Ana to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$113+ Flights from Santa Ana, CA to Indianapolis

Q: How much does it cost to fly round-trip from Santa Ana, California to Indianapolis?

Airfare is below average for this route at the moment. Santa Ana, California to Indianapolis flights typically cost between $403 and $666 in January. The cheapest round-trip price found within the last 3 days was $172 on Multiple Airlines (Jan 30-Feb 2).

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Santa Ana to Indianapolis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Santa Ana J. Wayne/Orange Cnty to Indianapolis are usually found in September or May, booked 72 days in advance, depart on a Saturday or Tuesday and return on a Friday

Cheap flight deals from Santa Ana to Indianapolis

Cheapest flights from Santa Ana to Indianapolis
Explore the most affordable flight options available from Santa Ana to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Wed 12/171:35 pmSNA - IND

1 stop27h 18mFrontier

Sun 1/254:30 pmIND - SNA

1 stop21h 18mFrontier

Deal found 12/11

$269

Mon 12/297:05 pmSNA - IND

1 stop8h 05mUnited Airlines

Thu 1/112:36 pmIND - SNA

1 stop9h 20mUnited Airlines

Deal found 12/10

$476

Wed 12/171:35 pmSNA - IND

1 stop27h 18mFrontier

Sat 12/208:38 pmIND - SNA

1 stop18h 57mFrontier

Deal found 12/10

$484

Mon 12/296:45 amSNA - IND

1 stop6h 09mMultiple Airlines

Thu 1/112:38 pmIND - SNA

3 stops24h 38mMultiple Airlines

Deal found 12/10

$504

Thu 12/2511:11 amSNA - IND

1 stop25h 43mMultiple Airlines

Wed 12/3112:43 pmIND - SNA

2 stops24h 33mMultiple Airlines

Deal found 12/10

$513

Mon 12/2911:35 amSNA - IND

2 stops7h 55mSouthwest

Thu 1/16:05 amIND - SNA

1 stop7h 55mSouthwest

Deal found 12/10

$532

Mon 12/2911:11 amSNA - IND

2 stops21h 22mSpirit Airlines

Thu 1/112:38 pmIND - SNA

3 stops24h 38mSpirit Airlines

Deal found 12/10

$552

Tue 12/2312:19 pmSNA - IND

1 stop8h 25mUnited Airlines

Wed 12/2412:36 pmIND - SNA

1 stop9h 20mUnited Airlines

Deal found 12/10

$560

Thu 12/257:04 amSNA - IND

2 stops12h 03mUnited Airlines

Wed 12/319:00 amIND - SNA

2 stops11h 48mUnited Airlines

Deal found 12/10

$564

Best flights from Santa Ana to Indianapolis
Discover carefully curated flight deals from Santa Ana to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Thu 1/292:39 pmSNA - IND

1 stop23h 05mMultiple Airlines

Mon 2/28:00 amIND - SNA

1 stop10h 42mMultiple Airlines

Deal found 12/11

$193

Wed 1/77:30 amSNA - IND

2 stops12h 19mDelta

Sat 1/106:35 amIND - SNA

2 stops14h 42mDelta

Deal found 12/10

$274

Fri 1/306:45 amSNA - IND

3 stops25h 41mSpirit Airlines

Mon 2/28:26 pmIND - SNA

3 stops27h 31mSpirit Airlines

Deal found 12/11

$288

Wed 1/71:17 pmSNA - IND

1 stop5h 58mUnited Airlines

Sat 1/109:00 amIND - SNA

1 stop7h 11mUnited Airlines

Deal found 12/10

$307

Thu 1/228:15 amSNA - IND

1 stop7h 50mAlaska Airlines

Sun 1/257:00 amIND - SNA

1 stop17h 27mAlaska Airlines

Deal found 12/9

$325

Fri 1/306:45 amSNA - IND

3 stops25h 41mMultiple Airlines

Mon 2/28:00 amIND - SNA

1 stop7h 25mMultiple Airlines

Deal found 12/11

$222

Fri 1/167:30 amSNA - IND

2 stops12h 41mDelta

Sun 1/187:00 amIND - SNA

1 stop7h 49mDelta

Deal found 12/10

$294

Wed 1/711:11 amSNA - IND

2 stops29h 20mSpirit Airlines

Sat 1/108:26 pmIND - SNA

3 stops27h 31mSpirit Airlines

Deal found 12/10

$336

Wed 1/77:30 amSNA - IND

2 stops12h 19mDelta

Thu 1/86:13 amIND - SNA

2 stops11h 21mDelta

Deal found 12/10

$345

Last-minute flights from Santa Ana to Indianapolis
Discover last-minute flight deals from Santa Ana to Indianapolis. Data last updated December 12, 2025 and is based on user searches.

Wed 12/171:35 pmSNA - IND

1 stop27h 18mFrontier

Sun 1/254:30 pmIND - SNA

1 stop21h 18mFrontier

Deal found 12/11

$269

Wed 1/77:30 amSNA - IND

2 stops12h 19mDelta

Sat 1/106:35 amIND - SNA

2 stops14h 42mDelta

Deal found 12/10

$274

Sat 1/103:28 pmSNA - IND

1 stop25h 32mFrontier

Mon 1/128:55 pmIND - SNA

1 stop21h 05mFrontier

Deal found 12/10

$254

Mon 1/126:45 amSNA - IND

1 stop6h 59mMultiple Airlines

Mon 1/128:55 pmIND - SNA

1 stop21h 05mMultiple Airlines

Deal found 12/10

$240

Thu 1/292:39 pmSNA - IND

1 stop23h 05mMultiple Airlines

Mon 2/28:00 amIND - SNA

1 stop10h 42mMultiple Airlines

Deal found 12/11

$193

Fri 1/306:45 amSNA - IND

1 stop6h 59mMultiple Airlines

Mon 2/28:00 amIND - SNA

1 stop7h 25mMultiple Airlines

Deal found 12/11

$172

One-way flights from Santa Ana to Indianapolis
Search for one-way flight options from Santa Ana to Indianapolis. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Wed 1/211:20 pmSNA - IND

2 stops23h 15mMultiple Airlines

Deal found 12/11

$113

Sat 1/173:55 pmSNA - IND

1 stop25h 12mFrontier

Deal found 12/10

$117

Sat 2/2812:25 pmSNA - IND

1 stop28h 32mFrontier

Deal found 12/10

$119

Tue 1/133:55 pmSNA - IND

3 stops42h 20mMultiple Airlines

Deal found 12/10

$123

Sun 1/1811:28 amSNA - IND

1 stop5h 39mFrontier

Deal found 12/10

$127

Tue 1/611:11 amSNA - IND

3 stops43h 32mMultiple Airlines

Deal found 12/9

$143

Sun 1/114:37 pmSNA - IND

3 stops27h 38mMultiple Airlines

Deal found 12/11

$149

Wed 1/218:15 amSNA - IND

1 stop7h 50mAlaska Airlines

Deal found 12/11

$152

Tue 1/66:45 amSNA - IND

1 stop8h 34mAlaska Airlines

Deal found 12/9

$153

Find flight deals from Santa Ana to Indianapolis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$172 (Mytrip)
One-way from	$113 (Kiwi.com)
Popular in	March
Cheapest in	September
Average price	$538

Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Indianapolis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Indianapolis flights.

Search Deals

From Santa Ana J. Wayne/Orange Cnty to Indianapolis

Search Deals

One-way flight from Santa Ana J. Wayne/Orange Cnty to Indianapolis

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($50 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 1/29

2:39 pm-4:44 pm

1 stop23h 05m

Indianapolis

Mon 2/2

8:00 am-3:42 pm

1 stop10h 42m

$193

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Fri 1/30

6:45 am-11:26 am

3 stops25h 41m

Indianapolis

Mon 2/2

8:00 am-12:25 pm

1 stop7h 25m

$222

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Wed 1/7

7:30 am-10:49 pm

2 stops12h 19m

Indianapolis

Sat 1/10

6:35 am-6:17 pm

2 stops14h 42m

$274

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Fri 1/30

6:45 am-11:26 am

3 stops25h 41m

Indianapolis

Mon 2/2

8:26 pm-8:57 pm

3 stops27h 31m

$288

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Fri 1/16

7:30 am-11:11 pm

2 stops12h 41m

Indianapolis

Sun 1/18

7:00 am-11:49 am

1 stop7h 49m

$294

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Wed 1/7

1:17 pm-10:15 pm

1 stop5h 58m

Indianapolis

Sat 1/10

9:00 am-1:11 pm

1 stop7h 11m

$307

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 1/22

8:15 am-7:05 pm

1 stop7h 50m

Indianapolis

Sun 1/25

7:00 am-9:27 pm

1 stop17h 27m

$325

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Wed 1/7

11:11 am-7:31 pm

2 stops29h 20m

Indianapolis

Sat 1/10

8:26 pm-8:57 pm

3 stops27h 31m

$336

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Wed 1/7

7:30 am-10:49 pm

2 stops12h 19m

Indianapolis

Thu 1/8

6:13 am-2:34 pm

2 stops11h 21m

$345

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

11:53 am-12:59 pm

1 stop22h 06m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 20 results

Compare providers for flights from Santa Ana to Indianapolis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Indianapolis in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Cheapflightsfares	Price Accuracy3 stars	Trust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Santa Ana, California-Indianapolis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Ana, California-Indianapolis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Indianapolis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Santa Ana, California-Indianapolis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Indianapolis

How far ahead should I book a flight from Santa Ana, California to Indianapolis?

The price you pay for your flight from Santa Ana, California to Indianapolis may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Ana, California to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Santa Ana, California to Indianapolis (average of $110). Flying from Santa Ana, California to Indianapolis in November is currently the most expensive (average of $176). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to IND?

A simple way to save on the total cost of your ticket is to fly from Santa Ana, California to Indianapolis in the afternoon. If you’re flexible enough to do this you can expect to save up to 37% on your trip compared to booking a flight in the morning.

How much does it cost to fly round-trip from Santa Ana, California to Indianapolis?

Reviews of airlines servicing Indianapolis

See what other customers who have flown with Southwest, Delta, and United Airlines from Santa Ana to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

United Airlines

7.4

Good

9,095 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Spirit Airlines

6.3

Okay

8,179 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

How long is the flight from Santa Ana, California to Indianapolis?
A quick flight from Santa Ana, California to Indianapolis can take about 12h 19m. Delta provides one of the quickest options available for as low as $274. Santa Ana, California and Indianapolis are separated by a distance of 1787 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Santa Ana, California to Indianapolis round-trip?
According to our current data, Spirit Airlines ($158), American Airlines ($286), and Delta ($286) offers the cheapest pricing from Santa Ana, California to Indianapolis. Spirit Airlines is currently priced 63% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Santa Ana, California to Indianapolis one-way?
To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $139. Delta flights start at $143 while deals on United Airlines start at $153 one-way.
Can I find deals for flights from Santa Ana to Indianapolis that include hotel bookings?
Yes. In addition to deals on Santa Ana to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to Indianapolis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Indianapolis.
Can I find deals for business class flights from Santa Ana to Indianapolis?
Yes. Cheapflights offers flight deals from Santa Ana to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana, California to Indianapolis?
Currently, June is the cheapest month in which you can book a flight from Santa Ana, California to Indianapolis (average of $110). Flying from Santa Ana, California to Indianapolis in November is currently the most expensive (average of $176). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Terre Haute

Muncie

Noblesville

Fishers

Greenwood

Anderson

Kokomo

Plainfield

Franklin

Carmel

Crawfordsville

Bloomington

Speedway

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Santa Ana to Indianapolis

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$158	Average$230	FlexibilityNo cancel fee	On-time65%
Delta	Cheapest$286	Average$439	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$286	Average$444	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$321	Average$436	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$350	Average$516	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$113+ Cheap flights from Santa Ana, CA to Indianapolis (SNA - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to Indianapolis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Santa Ana J. Wayne/Orange Cnty to Indianapolis are usually found in September or May, booked 72 days in advance, depart on a Saturday or Tuesday and return on a Friday

Cheap flight deals from Santa Ana to Indianapolis

Cheapest flights from Santa Ana to IndianapolisExplore the most affordable flight options available from Santa Ana to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Santa Ana to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Santa Ana to Indianapolis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Indianapolis that are best for you.

Compare providers for flights from Santa Ana to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Indianapolis in December.

Best time to book a flight from Santa Ana to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Indianapolis

How far ahead should I book a flight from Santa Ana, California to Indianapolis?

What is the cheapest month to book a flight from Santa Ana, California to Indianapolis?

What is the cheapest time of day to fly from SNA to IND?

How much does it cost to fly round-trip from Santa Ana, California to Indianapolis?

Reviews of airlines servicing Indianapolis

See what other customers who have flown with Southwest, Delta, and United Airlines from Santa Ana to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Santa Ana, California to Indianapolis?

What are the cheapest airlines flying from Santa Ana, California to Indianapolis round-trip?

What are the cheapest airlines to fly from Santa Ana, California to Indianapolis one-way?

Can I find deals for flights from Santa Ana to Indianapolis that include hotel bookings?

How can I find direct flights from Santa Ana to Indianapolis?

Can I find deals for business class flights from Santa Ana to Indianapolis?

What is the cheapest month to book a flight from Santa Ana, California to Indianapolis?

Traveling to a place near Indianapolis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Santa Ana to Indianapolis

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Santa Ana to Indianapolis
Explore the most affordable flight options available from Santa Ana to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.