What are the cheapest airlines flying from Santa Ana to Indianapolis round-trip?

Spirit Airlines, at $158, was found to be the cheapest airline from Santa Ana to Indianapolis.Alternate airlines to your destination round-trip include American Airlines and Delta. Spirit Airlines is currently priced 66% below the average price you’ll pay for this route.

What is the cheapest day to fly from Santa Ana to Indianapolis?

Travelers seeking maximum savings on their Santa Ana to Indianapolis flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

What are the most popular airlines that fly from Santa Ana to Indianapolis?

Consider American Airlines, Delta or Spirit Airlines when booking your flight. These represent the most popular airlines when flying from Santa Ana to Indianapolis.

What is the cheapest day to fly round-trip from Santa Ana to Indianapolis?

Departing on a Friday is a good option for securing a great price. You can expect to save up to 29% when planning your travel around this day of the week.

How far in advance should I book a flight from Santa Ana to Indianapolis?

Travelers have found it’s best to book a flight 42 days in advance to save up to 58% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 42 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Santa Ana to Indianapolis 1-2 weeks in advance for as low as $389, or $489 for flights within the next 24 hours.

What is the cheapest month to fly from Santa Ana to Indianapolis?

August is one of the best times of the year to fly to Indianapolis from Santa Ana. Prices for August average $387 per person but you can even find prices for as low as $128. The most expensive prices can be found in the month of December. Opting for a August flight can save you 19% on your journey compared to booking in December

Can I find deals for flights from Santa Ana to Indianapolis that include hotel bookings?

Yes. In addition to deals on Santa Ana to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to Indianapolis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Indianapolis.

Can I find deals for business class flights from Santa Ana to Indianapolis?

Yes. Cheapflights offers flight deals from Santa Ana to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$83+ Cheap Flights from Santa Ana to Indianapolis

Q: How much does it cost to fly round-trip from Santa Ana to Indianapolis?

Airfare is below average for this route at the moment. Santa Ana to Indianapolis flights typically cost between $386 and $556 in October. The cheapest round-trip price found within the last 3 days was $191 on Frontier (Oct 31-Nov 2).

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Cheapflights Tip: The best prices from Santa Ana J. Wayne/Orange Cnty to Indianapolis are usually found in July or May, booked 72 days in advance, depart on a Saturday or Tuesday and return on a Friday

Cheap flight deals from Santa Ana to Indianapolis

Round-trip from	$191 (CheapOair)
One-way from	$83 (CheapOair)
Popular in	March
Cheapest in	July
Average price	$486

From Santa Ana J. Wayne/Orange Cnty to Indianapolis

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One-way flight from Santa Ana J. Wayne/Orange Cnty to Indianapolis

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Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Santa Ana to Indianapolis

Cheapest flights from Santa Ana to Indianapolis
Explore the most affordable flight options available from Santa Ana to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Sat 9/612:58 pmSNA - IND

1 stop28h 06mFrontier

Mon 9/88:54 pmIND - SNA

1 stop18h 19mFrontier

Deal found 8/14

$154

Fri 10/3112:01 pmSNA - IND

1 stop24h 34mFrontier

Sun 11/28:39 pmIND - SNA

1 stop17h 37mFrontier

Deal found 8/14

$191

Fri 9/2611:52 amSNA - IND

1 stop25h 22mFrontier

Mon 9/298:54 pmIND - SNA

1 stop18h 19mFrontier

Deal found 8/14

$193

Fri 9/126:45 amSNA - IND

1 stop8h 06mSpirit Airlines

Sat 9/134:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/14

$194

Thu 9/116:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sat 9/134:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/11

$195

Thu 9/46:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sat 9/64:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/12

$197

Wed 9/2412:58 pmSNA - IND

1 stop28h 06mMultiple Airlines

Sun 9/288:33 pmIND - SNA

1 stop18h 32mMultiple Airlines

Deal found 8/13

$204

Thu 10/26:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sun 10/58:38 amIND - SNA

1 stop13h 36mSpirit Airlines

Deal found 8/14

$205

Sat 9/206:45 amSNA - IND

1 stop5h 58mSpirit Airlines

Sat 9/274:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/12

$207

Fri 9/1211:52 amSNA - IND

1 stop25h 22mMultiple Airlines

Sun 9/148:33 pmIND - SNA

1 stop18h 32mMultiple Airlines

Deal found 8/14

$209

Thu 9/116:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sun 9/148:33 pmIND - SNA

1 stop18h 32mSpirit Airlines

Deal found 8/12

$211

Fri 8/2212:09 pmSNA - IND

1 stop24h 31mFrontier

Sun 8/248:59 pmIND - SNA

1 stop17h 25mFrontier

Deal found 8/14

$216

Best flights from Santa Ana to Indianapolis
Discover carefully curated flight deals from Santa Ana to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2025.

Fri 10/3112:01 pmSNA - IND

1 stop24h 34mFrontier

Sun 11/28:39 pmIND - SNA

1 stop17h 37mFrontier

Deal found 8/14

$191

Thu 10/306:45 amSNA - IND

2 stops7h 52mSpirit Airlines

Sat 11/16:23 pmIND - SNA

1 stop6h 40mSpirit Airlines

Deal found 8/12

$194

Fri 9/1211:52 amSNA - IND

1 stop25h 22mMultiple Airlines

Sun 9/148:33 pmIND - SNA

1 stop18h 32mMultiple Airlines

Deal found 8/14

$204

Thu 9/116:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sat 9/134:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/11

$195

Wed 9/2412:58 pmSNA - IND

1 stop28h 06mMultiple Airlines

Sun 9/288:33 pmIND - SNA

1 stop18h 32mMultiple Airlines

Deal found 8/13

$204

Thu 9/46:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sat 9/64:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/12

$197

Fri 9/126:45 amSNA - IND

1 stop8h 06mSpirit Airlines

Sat 9/134:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/13

$197

Fri 10/246:45 amSNA - IND

1 stop7h 43mSpirit Airlines

Sun 10/268:38 amIND - SNA

1 stop13h 36mSpirit Airlines

Deal found 8/13

$204

Thu 10/26:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sun 10/58:38 amIND - SNA

1 stop13h 36mSpirit Airlines

Deal found 8/14

$205

Sat 9/206:45 amSNA - IND

1 stop5h 58mSpirit Airlines

Sat 9/274:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/12

$207

Last-minute flights from Santa Ana to Indianapolis
Discover last-minute flight deals from Santa Ana to Indianapolis. Data last updated August 14, 2025 and is based on user searches.

Wed 8/208:30 pmSNA - IND

1 stop19h 25mMultiple Airlines

Sun 8/248:59 pmIND - SNA

1 stop17h 25mMultiple Airlines

Deal found 8/12

$340

Thu 8/216:45 amSNA - IND

1 stop9h 10mMultiple Airlines

Sun 8/248:59 pmIND - SNA

1 stop17h 25mMultiple Airlines

Deal found 8/12

$312

Fri 8/2212:09 pmSNA - IND

1 stop24h 31mFrontier

Sun 8/248:59 pmIND - SNA

1 stop17h 25mFrontier

Deal found 8/14

$216

Fri 8/226:45 amSNA - IND

2 stops12h 31mMultiple Airlines

Mon 8/251:37 pmIND - SNA

1 stop7h 42mMultiple Airlines

Deal found 8/12

$347

Fri 8/226:45 amSNA - IND

2 stops12h 31mSpirit Airlines

Mon 8/251:48 pmIND - SNA

2 stops10h 33mSpirit Airlines

Deal found 8/12

$467

Thu 9/46:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sat 9/64:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/12

$197

Sat 9/612:58 pmSNA - IND

1 stop28h 06mFrontier

Mon 9/88:54 pmIND - SNA

1 stop18h 19mFrontier

Deal found 8/14

$154

Thu 9/116:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sat 9/134:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/11

$195

Thu 9/116:45 amSNA - IND

1 stop9h 43mSpirit Airlines

Sun 9/148:33 pmIND - SNA

1 stop18h 32mSpirit Airlines

Deal found 8/12

$211

Fri 9/126:45 amSNA - IND

1 stop8h 06mSpirit Airlines

Sat 9/134:43 pmIND - SNA

1 stop8h 22mSpirit Airlines

Deal found 8/14

$194

Fri 9/1211:52 amSNA - IND

1 stop25h 22mMultiple Airlines

Sun 9/148:33 pmIND - SNA

1 stop18h 32mMultiple Airlines

Deal found 8/14

$209

Fri 9/196:45 amSNA - IND

1 stop8h 06mSpirit Airlines

Mon 9/2211:48 amIND - SNA

1 stop13h 17mSpirit Airlines

Deal found 8/13

$225

One-way flights from Santa Ana to Indianapolis
Search for one-way flight options from Santa Ana to Indianapolis. Find affordable one-way fares based on user searches. Data last updated August 14, 2025.

Wed 10/112:58 pmSNA - IND

1 stop28h 06mFrontier

Deal found 8/13

$83

Thu 10/306:45 amSNA - IND

2 stops7h 52mSpirit Airlines

Deal found 8/13

$91

Sat 12/67:15 amSNA - IND

1 stop10h 40mSpirit Airlines

Deal found 8/11

$99

Sat 9/206:45 amSNA - IND

1 stop5h 58mSpirit Airlines

Deal found 8/12

$102

Fri 9/196:45 amSNA - IND

1 stop8h 06mSpirit Airlines

Deal found 8/11

$107

Wed 11/55:46 pmSNA - IND

2 stops15h 47mSpirit Airlines

Deal found 8/13

$108

Sat 9/136:45 amSNA - IND

1 stop5h 58mSpirit Airlines

Deal found 8/12

$109

Fri 8/226:45 amSNA - IND

2 stops12h 31mSpirit Airlines

Deal found 8/11

$115

Mon 9/156:45 amSNA - IND

1 stop8h 06mSpirit Airlines

Deal found 8/12

$116

Sat 9/203:29 pmSNA - IND

2 stops23h 49mFrontier

Deal found 8/13

$120

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Fri 10/31

12:01 pm-3:35 pm

1 stop24h 34m

Indianapolis

Sun 11/2

8:39 pm-11:16 am

1 stop17h 37m

$191

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 10/30

6:45 am-5:37 pm

2 stops7h 52m

Indianapolis

Sat 11/1

6:23 pm-10:03 pm

1 stop6h 40m

$194

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 9/11

6:45 am-7:28 pm

1 stop9h 43m

Indianapolis

Sat 9/13

4:43 pm-10:05 pm

1 stop8h 22m

$195

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 9/4

6:45 am-7:28 pm

1 stop9h 43m

Indianapolis

Sat 9/6

4:43 pm-10:05 pm

1 stop8h 22m

$197

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Fri 9/12

6:45 am-5:51 pm

1 stop8h 06m

Indianapolis

Sat 9/13

4:43 pm-10:05 pm

1 stop8h 22m

$197

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Fri 9/12

11:52 am-4:14 pm

1 stop25h 22m

Indianapolis

Sun 9/14

8:33 pm-12:05 pm

1 stop18h 32m

$204

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Wed 9/24

12:58 pm-8:04 pm

1 stop28h 06m

Indianapolis

Sun 9/28

8:33 pm-12:05 pm

1 stop18h 32m

$204

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Fri 10/24

6:45 am-5:28 pm

1 stop7h 43m

Indianapolis

Sun 10/26

8:38 am-7:14 pm

1 stop13h 36m

$204

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Thu 10/2

6:45 am-7:28 pm

1 stop9h 43m

Indianapolis

Sun 10/5

8:38 am-7:14 pm

1 stop13h 36m

$205

Santa AnaIndianapolis

SNA - IND

SNAIND

Santa Ana J. Wayne/Orange Cnty

Sat 9/20

6:45 am-3:43 pm

1 stop5h 58m

Indianapolis

Sat 9/27

4:43 pm-10:05 pm

1 stop8h 22m

$207

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 22 results

Best time to book a flight from Santa Ana to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Indianapolis

How far ahead should I book a flight from Santa Ana to Indianapolis?

Booking 71 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santa Ana to Indianapolis. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santa Ana to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Santa Ana to Indianapolis (average of $297). Flying from Santa Ana to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to IND?

A simple way to save on the total cost of your ticket is to fly from Santa Ana to Indianapolis in the afternoon. If you’re flexible enough to do this you can expect to save up to 38% on your trip compared to booking a flight in the morning.

How much does it cost to fly round-trip from Santa Ana to Indianapolis?

Reviews of airlines servicing Indianapolis

See what other customers who have flown with Southwest, Delta, and United Airlines from Santa Ana to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,244 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,244 reviews

Southwest

8.0

Very good

4,244 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

8.0

Very good

7,980 reviews

Southwest

8.0

Very good

4,244 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

8,916 reviews

Southwest

8.0

Very good

4,244 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,244 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Spirit Airlines

6.3

Okay

8,046 reviews

Southwest

8.0

Very good

4,244 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What are the cheapest airlines flying from Santa Ana to Indianapolis round-trip?
Spirit Airlines, at $158, was found to be the cheapest airline from Santa Ana to Indianapolis.Alternate airlines to your destination round-trip include American Airlines and Delta. Spirit Airlines is currently priced 66% below the average price you’ll pay for this route.
Can I find deals for flights from Santa Ana to Indianapolis that include hotel bookings?
Yes. In addition to deals on Santa Ana to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to Indianapolis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Indianapolis.
Can I find deals for business class flights from Santa Ana to Indianapolis?
Yes. Cheapflights offers flight deals from Santa Ana to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana to Indianapolis?
Currently, August is the cheapest month in which you can book a flight from Santa Ana to Indianapolis (average of $297). Flying from Santa Ana to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Greenwood

Bloomington

Muncie

Noblesville

Fishers

Terre Haute

Anderson

Kokomo

Franklin

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Carmel

Crawfordsville

Shelbyville

Speedway

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Santa Ana to Indianapolis

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$158	Average$232	FlexibilityNo cancel fee	On-time65%
Delta	Cheapest$286	Average$468	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$286	Average$474	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$327	Average$475	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$389	Average$485	FlexibilityNo cancel fee	On-time63%

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$83+ Cheap flights from Santa Ana to Indianapolis (SNA - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to Indianapolis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Santa Ana J. Wayne/Orange Cnty to Indianapolis are usually found in July or May, booked 72 days in advance, depart on a Saturday or Tuesday and return on a Friday

Cheap flight deals from Santa Ana to Indianapolis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santa Ana to Indianapolis

Cheapest flights from Santa Ana to IndianapolisExplore the most affordable flight options available from Santa Ana to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Explore the most affordable flight options available from Santa Ana to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Indianapolis that are best for you.

Best time to book a flight from Santa Ana to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Indianapolis

How far ahead should I book a flight from Santa Ana to Indianapolis?

Use this chart to determine the optimal time to book a round-trip flight from Santa Ana to Indianapolis. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Santa Ana to Indianapolis?

What is the cheapest time of day to fly from SNA to IND?

Find hourly flight availability from Santa Ana to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

How much does it cost to fly round-trip from Santa Ana to Indianapolis?

Reviews of airlines servicing Indianapolis

See what other customers who have flown with Southwest, Delta, and United Airlines from Santa Ana to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santa Ana to Indianapolis round-trip?

Can I find deals for flights from Santa Ana to Indianapolis that include hotel bookings?

How can I find direct flights from Santa Ana to Indianapolis?

Can I find deals for business class flights from Santa Ana to Indianapolis?

What is the cheapest month to book a flight from Santa Ana to Indianapolis?

Traveling to a place near Indianapolis?

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Alternative routes for Santa Ana to Indianapolis

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Top 5 airlines flying from Santa Ana to Indianapolis

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Cheapest flights from Santa Ana to Indianapolis
Explore the most affordable flight options available from Santa Ana to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.