$68+ Cheap flights from Mesa, AZ to Indianapolis (IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Mesa to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mesa to Indianapolis
Cheapest flights from Mesa to IndianapolisExplore the most affordable flight options available from Mesa to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
Explore the most affordable flight options available from Mesa to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Trip.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from Mesa to Indianapolis
Keep the following information in mind while searching for Mesa to Indianapolis flight deals. Data was last updated January 29, 2026.
Round-trip from | $160 (Kiwi.com) |
|---|---|
One-way from | $68 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $441 |
Cheapflights Fare Finder
Use the filters below to find and compare flights from Mesa to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Fri 2/27
6:00 am-7:47 pm
1 stop11h 47m
Indianapolis
Fri 3/6
8:33 pm-8:42 am
1 stop14h 09m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Fri 3/6
9:52 am-7:38 pm
1 stop7h 46m
Indianapolis
Mon 3/9
8:52 pm-10:59 am
2 stops17h 07m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Thu 2/26
10:51 pm-7:47 pm
1 stop18h 56m
Indianapolis
Thu 3/5
7:27 pm-8:42 am
2 stops39h 15m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Sat 2/21
5:40 pm-3:54 pm
1 stop20h 14m
Indianapolis
Mon 2/23
10:05 am-12:55 am
1 stop16h 50m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Sat 2/14
5:40 pm-3:54 pm
1 stop20h 14m
Indianapolis
Mon 2/16
8:02 pm-1:44 pm
2 stops19h 42m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Tue 4/21
1:23 pm-11:57 pm
1 stop7h 34m
Indianapolis
Wed 4/22
6:00 am-9:22 am
1 stop6h 22m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Wed 3/11
6:50 am-7:38 pm
1 stop9h 48m
Indianapolis
Wed 3/18
8:33 pm-7:42 am
1 stop14h 09m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Fri 4/3
6:50 am-7:35 pm
1 stop9h 45m
Indianapolis
Tue 4/7
8:33 pm-8:16 pm
2 stops26h 43m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Sat 3/14
8:52 am-7:38 pm
1 stop7h 46m
Indianapolis
Wed 3/18
6:15 am-4:34 pm
2 stops13h 19m
PhoenixIndianapolis
PHX - IND
PHXIND
Phoenix Sky Harbor Intl
Fri 4/3
6:50 am-7:35 pm
1 stop9h 45m
Indianapolis
Tue 4/7
6:15 am-10:36 am
2 stops31h 21m
Best time to book a flight from Mesa to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Mesa with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Indianapolis
How far ahead should I book a flight from Mesa to Indianapolis?
Use this chart to determine the optimal time to book a round-trip flight from Mesa to Indianapolis. Price data was last updated on January 23, 2026.
To ensure you get the cheapest price possible for a flight from Mesa to Indianapolis, you should look to book at least 85 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Mesa to Indianapolis?
Currently, February is the cheapest month in which you can book a flight from Mesa to Indianapolis (average of $69). Flying from Mesa to Indianapolis in June is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MS9 to IND?
Find hourly flight availability from Mesa to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.
A simple way to save on the total cost of your ticket is to fly from Mesa to Indianapolis in the afternoon. If you’re flexible enough to do this you can expect to save up to 10% on your trip compared to booking a flight at noon.
What is the cheapest day to fly from Mesa to Indianapolis?
Use this chart to determine the cheapest time to fly round-trip from Mesa to Indianapolis. Price data was last updated on January 24, 2026.
Travelers seeking maximum savings on their Mesa to Indianapolis flight should consider departing on Saturday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated January 29, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Mesa to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
Crew
Comfort
Overall
Boarding
Food
Reviews
Thomas,Dec 2025
SEA - DEN
Entertainment
Crew
Comfort
Overall
Boarding
Food
Reviews
Thomas,Dec 2025
SEA - DEN
Entertainment
Crew
Comfort
Overall
Boarding
Food
Reviews
Thomas,Dec 2025
SEA - DEN
Entertainment
Crew
Comfort
Overall
Boarding
Food
Reviews
Thomas,Dec 2025
SEA - DEN
Entertainment
Crew
Comfort
Overall
Boarding
Food
Reviews
Thomas,Dec 2025
SEA - DEN
Entertainment
Crew
Comfort
Overall
Boarding
Food
Reviews
Thomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Mesa to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Mesa to Indianapolis
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from Mesa to Indianapolis
Discover the top 6 airlines that operate flights from Mesa to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$100 | Average$231 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$119 | Average$237 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$163 | Average$324 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$270 | Average$336 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$273 | Average$462 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$321 | Average$474 | FlexibilityNo cancel fee | On-time63% |