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$75+ Cheap flights from Mesa, AZ to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — IND
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to Indianapolis are usually found in September or January, booked 16 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Mesa to Indianapolis

Keep the following information in mind while searching for Mesa to Indianapolis flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$147
(Priceline)

One-way from

$75
(Kiwi.com)

Popular in

July

Cheapest in

September

Average price

$319
From Mesa to Indianapolis
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One-way flight from Mesa to Indianapolis
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Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mesa to Indianapolis

Cheapest flights from Mesa to Indianapolis
Explore the most affordable flight options available from Mesa to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/75:35 amPHX - IND
1 stop6h 39mFrontier
sáb. 11/154:20 pmIND - PHX
1 stop7h 38mFrontier
Deal found 9/14$147
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/121:16 pmPHX - IND
1 stop28h 15mFrontier
dom. 11/168:39 pmIND - PHX
1 stop13h 45mFrontier
Deal found 9/13$150
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/1011:24 pmPHX - IND
1 stop30h 20mFrontier
vie. 10/178:51 pmIND - PHX
1 stop17h 23mFrontier
Deal found 9/14$151
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/256:32 amPHX - IND
1 stop10h 32mFrontier
sáb. 9/275:01 pmIND - PHX
1 stop7h 52mFrontier
Deal found 9/14$152
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/38:37 amPHX - IND
1 stop8h 27mFrontier
mié. 10/85:24 pmIND - PHX
1 stop7h 31mFrontier
Deal found 9/13$161
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/116:36 amPHX - IND
1 stop6h 53mFrontier
vie. 10/178:51 pmIND - PHX
1 stop17h 23mFrontier
Deal found 9/13$164
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/96:00 amPHX - IND
1 stop25h 36mFrontier
jue. 10/233:33 pmIND - PHX
1 stop10h 43mFrontier
Deal found 9/14$174
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/249:21 amPHX - IND
1 stop7h 45mFrontier
lun. 10/273:34 pmIND - PHX
1 stop9h 58mFrontier
Deal found 9/14$182
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/139:21 amPHX - IND
1 stop7h 03mFrontier
lun. 10/208:51 pmIND - PHX
1 stop21h 13mFrontier
Deal found 9/13$185
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/1210:59 pmPHX - IND
1 stop10h 18mFrontier
dom. 10/198:51 pmIND - PHX
1 stop28h 25mFrontier
Deal found 9/14$186
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/145:35 amPHX - IND
1 stop10h 29mFrontier
dom. 11/1610:21 pmIND - PHX
2 stops14h 41mFrontier
Deal found 9/13$189
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/207:21 amPHX - IND
1 stop9h 45mFrontier
jue. 10/233:33 pmIND - PHX
1 stop10h 43mFrontier
Deal found 9/14$196

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Mesa to Indianapolis that are best for you.

Fly from

Mesa

Fly to

Indianapolis

Route

Depart

Return

Price

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

vie. 10/10

12:02 pm-4:29 pm

1 stop25h 27m

Indianapolis

vie. 10/17

8:51 pm-11:14 am

1 stop17h 23m

$164

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

sáb. 11/1

6:11 pm-9:44 am

2 stops12h 33m

Indianapolis

sáb. 11/8

4:20 pm-9:58 pm

1 stop7h 38m

$201

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

jue. 9/25

12:31 pm-6:44 pm

1 stop27h 13m

Indianapolis

lun. 9/29

12:06 pm-1:05 pm

2 stops27h 59m

$229

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

vie. 9/19

8:37 am-8:04 pm

1 stop8h 27m

Indianapolis

jue. 9/25

8:54 pm-11:27 pm

1 stop5h 33m

$244

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

jue. 9/18

8:20 pm-8:04 pm

1 stop20h 44m

Indianapolis

sáb. 9/20

5:01 pm-9:34 am

1 stop19h 33m

$286

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

lun. 10/13

6:00 pm-12:20 am

Nonstop3h 20m

Indianapolis

lun. 10/20

7:05 pm-7:55 pm

Nonstop3h 50m

$289

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

jue. 10/23

3:50 pm-10:18 pm

Nonstop3h 28m

Indianapolis

dom. 10/26

5:30 am-6:25 am

Nonstop3h 55m

$317

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

lun. 10/20

6:00 pm-12:20 am

Nonstop3h 20m

Indianapolis

mié. 11/5

6:05 am-8:15 am

Nonstop4h 10m

$317

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

vie. 10/24

6:00 pm-12:20 am

Nonstop3h 20m

Indianapolis

dom. 10/26

7:35 am-8:25 am

Nonstop3h 50m

$317

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

vie. 11/7

8:55 am-2:15 pm

Nonstop3h 20m

Indianapolis

dom. 11/9

5:35 pm-7:30 pm

Nonstop3h 55m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 21 results
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Best time to book a flight from Mesa to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Indianapolis

How far ahead should I book a flight from Mesa to Indianapolis?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Indianapolis. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Mesa to Indianapolis, you should look to book at least 16 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mesa to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Mesa to Indianapolis (average of $286). Flying from Mesa to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to IND?

Find hourly flight availability from Mesa to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Indianapolis as you normally would.

What is the cheapest day to fly from Mesa to Indianapolis?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Indianapolis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to Indianapolis flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated septiembre 15, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Mesa to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,015 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,172 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mesa to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Mesa?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Mesa to Indianapolis. You should not have trouble finding flights to Indianapolis from Mesa; the airport handles an average of 4 inbound flights from Mesa per day. You should also have plenty of airline options to choose from since 6 airlines have flights to the Indianapolis airport from Mesa. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How long is the flight from Mesa to Indianapolis?

    Frontier can get you from Mesa to Indianapolis in just under 25h 27m. Your travel time can differ by up to . Airlines will cover a distance of 1484 mi.

  • What are the most reliable airlines from Mesa to Indianapolis?

    Consider Southwest (81%), American Airlines (48%) or Alaska Airlines (48%) when booking your flight. These represent the most reliable airlines when flying from Mesa to Indianapolis.

  • What are the cheapest flights from Mesa to Indianapolis?

    While on average a flight from Mesa to Indianapolis is generally $387, our data shows the cheapest flight currently is $138. When looking at the most popular route, (Phoenix Sky Harbor Intl - Indianapolis), you can expect to pay $196 for that flight.

  • Can I find deals for flights from Mesa to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Mesa to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Indianapolis.

  • Can I find deals for business class flights from Mesa to Indianapolis?

    Yes. Cheapflights offers flight deals from Mesa to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Mesa to Indianapolis (average of $286). Flying from Mesa to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mesa to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Mesa to Indianapolis

Discover the top 6 airlines that operate flights from Mesa to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$100Average$222FlexibilityNo cancel feeOn-time65%
FrontierCheapest$128Average$240FlexibilityNo cancel feeOn-time62%
DeltaCheapest$204Average$366FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$285Average$530FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$303Average$472FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$331Average$471FlexibilityNo cancel feeOn-time63%

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