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$109+ Cheap flights from Mesa, AZ to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — IND
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to Indianapolis are usually found in September or August, booked 75 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Mesa to Indianapolis

Keep the following information in mind while searching for Mesa to Indianapolis flight deals. Data was last updated July 31, 2025.

Round-trip from

$216
(Cheapflightsfares)

One-way from

$109
(Frontier)

Popular in

July

Cheapest in

September

Average price

$471
From Mesa to Indianapolis
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One-way flight from Mesa to Indianapolis
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Mesa to Indianapolis

Cheapest flights from Mesa to Indianapolis
Explore the most affordable flight options available from Mesa to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/711:09 amPHX - IND
1 stop5h 55mFrontier
Thu 9/118:54 pmIND - PHX
1 stop5h 33mFrontier
Deal found 7/29$216
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/209:19 amPHX - IND
Nonstop3h 41mAmerican Airlines
Wed 8/276:07 amIND - PHX
Nonstop3h 43mAmerican Airlines
Deal found 7/31$277
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2512:14 pmPHX - IND
1 stop19h 39mSpirit Airlines
Wed 10/17:43 pmIND - PHX
1 stop18h 13mSpirit Airlines
Deal found 7/30$285
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/209:00 amPHX - IND
Nonstop3h 30mSouthwest
Sat 8/237:35 amIND - PHX
1 stop10h 25mSouthwest
Deal found 7/29$287
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/214:19 pmPHX - IND
2 stops23h 42mMultiple Airlines
Wed 10/17:43 pmIND - PHX
1 stop18h 13mMultiple Airlines
Deal found 7/30$289
This Alaska Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:00 pmPHX - IND
1 stop21h 02mAlaska Airlines
Tue 10/217:00 amIND - PHX
1 stop10h 44mAlaska Airlines
Deal found 7/29$296
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2711:59 pmPHX - IND
1 stop7h 27mDelta
Wed 9/31:55 pmIND - PHX
1 stop6h 57mDelta
Deal found 7/30$297
This Hawaiian Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Hawaiian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/43:58 pmPHX - IND
1 stop10h 12mHawaiian Airlines
Tue 9/96:30 amIND - PHX
1 stop11h 28mHawaiian Airlines
Deal found 7/29$311
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:05 amPHX - IND
2 stops7h 27mUnited Airlines
Wed 9/311:20 amIND - PHX
1 stop6h 19mUnited Airlines
Deal found 7/30$313

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Mesa to Indianapolis that are best for you.

Fly from

Mesa

Fly to

Indianapolis

Route

Depart

Return

Price

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Sun 9/7

11:09 am-8:04 pm

1 stop5h 55m

Indianapolis

Thu 9/11

8:54 pm-11:27 pm

1 stop5h 33m

$216

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Wed 8/20

9:19 am-4:00 pm

Nonstop3h 41m

Indianapolis

Sat 8/23

6:07 am-6:50 am

Nonstop3h 43m

$277

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Thu 9/11

10:59 pm-11:11 pm

2 stops21h 12m

Indianapolis

Mon 9/15

5:00 am-10:04 pm

2 stops20h 04m

$279

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Wed 8/20

9:00 am-3:30 pm

Nonstop3h 30m

Indianapolis

Sat 8/23

7:35 am-3:00 pm

1 stop10h 25m

$287

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Sun 9/21

4:19 pm-7:01 pm

2 stops23h 42m

Indianapolis

Wed 10/1

7:43 pm-10:56 am

1 stop18h 13m

$289

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Tue 10/14

6:00 pm-6:02 pm

1 stop21h 02m

Indianapolis

Tue 10/21

7:00 am-2:44 pm

1 stop10h 44m

$296

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Wed 8/27

11:59 pm-10:26 am

1 stop7h 27m

Indianapolis

Wed 9/3

1:55 pm-5:52 pm

1 stop6h 57m

$297

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Thu 9/4

3:58 pm-5:10 am

1 stop10h 12m

Indianapolis

Tue 9/9

6:30 am-2:58 pm

1 stop11h 28m

$311

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Wed 8/27

6:05 am-4:32 pm

2 stops7h 27m

Indianapolis

Wed 9/3

11:20 am-2:39 pm

1 stop6h 19m

$313

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Tue 8/5

2:03 pm-12:43 am

1 stop7h 40m

$109

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 17 results
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Best time to book a flight from Mesa to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Indianapolis

How far ahead should I book a flight from Mesa to Indianapolis?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Indianapolis. Price data was last updated on July 25, 2025.

To ensure you get the cheapest price possible for a flight from Mesa to Indianapolis, you should look to book at least 75 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mesa to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Mesa to Indianapolis (average of $297). Flying from Mesa to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to IND?

Find hourly flight availability from Mesa to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Indianapolis as you normally would.

What is the cheapest day to fly from Mesa to Indianapolis?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Indianapolis. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to Indianapolis flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated July 31, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Mesa to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Southwest
8.0
Very good
4,246 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Hawaiian Airlines
7.8
Good
2,611 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,900 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Mesa?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Mesa to Indianapolis. You should not have trouble finding flights to Indianapolis from Mesa; the airport handles an average of 4 inbound flights from Mesa per day. You should also have plenty of airline options to choose from since 6 airlines have flights to the Indianapolis airport from Mesa. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • What are the cheapest airlines to fly from Mesa to Indianapolis one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $109. Users have also found prices from $133 and $139 on Spirit Airlines and Southwest, respectively.

  • What are the most reliable airlines from Mesa to Indianapolis?

    Consider Southwest (71%), American Airlines (49%) or Alaska Airlines (49%) when booking your flight. These represent the most reliable airlines when flying from Mesa to Indianapolis.

  • What are the cheapest flights from Mesa to Indianapolis?

    While on average a flight from Mesa to Indianapolis is generally $317, our data shows the cheapest flight currently is $148. When looking at the most popular route, (Phoenix Sky Harbor Intl - Indianapolis), you can expect to pay $245 for that flight.

  • Can I find deals for flights from Mesa to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Mesa to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Indianapolis.

  • Can I find deals for business class flights from Mesa to Indianapolis?

    Yes. Cheapflights offers flight deals from Mesa to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Mesa to Indianapolis (average of $297). Flying from Mesa to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Greenwood
Bloomington
Noblesville
Muncie
Fishers
Terre Haute
Anderson
Kokomo
Franklin
Plainfield
Carmel
Crawfordsville
Shelbyville
Speedway

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Alternative routes for Mesa to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Mesa to Indianapolis

Discover the top 6 airlines that operate flights from Mesa to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$100Average$207FlexibilityNo cancel feeOn-time65%
FrontierCheapest$112Average$239FlexibilityNo cancel feeOn-time62%
DeltaCheapest$216Average$330FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$268Average$442FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$276Average$528FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$328Average$471FlexibilityNo cancel feeOn-time63%

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