$146+ Cheap flights from Knoxville to Indianapolis (TYS - IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Aug 7 — Aug 141
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to IndianapolisExplore the most affordable flight options available from Knoxville to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
Explore the most affordable flight options available from Knoxville to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:12 pm
TYS
- IND
1 stop6h 15m
Delta
Thu 8/137:02 am
IND
- TYS
1 stop6h 32m
Delta
Deal found 7/8![Delta logo]()
$221
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 am
TYS
- IND
2 stops7h 40m
Southwest
Mon 8/176:55 am
IND
- TYS
1 stop5h 25m
Southwest
Deal found 7/7![Southwest logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:01 pm
TYS
- IND
2 stops21h 43m
Multiple Airlines
Tue 10/271:33 pm
IND
- TYS
1 stop20h 32m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:00 am
TYS
- IND
2 stops10h 35m
Southwest
Sat 11/72:45 pm
IND
- TYS
1 stop2h 55m
Southwest
Deal found 7/7![Southwest logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:11 pm
TYS
- IND
2 stops14h 14m
Multiple Airlines
Sun 8/29:22 pm
IND
- TYS
1 stop23h 53m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:00 am
TYS
- IND
2 stops9h 55m
Southwest
Sat 9/52:30 pm
IND
- TYS
1 stop3h 10m
Southwest
Deal found 7/8![Southwest logo]()
$251
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:25 pm
TYS
- IND
1 stop3h 48m
American Airlines
Sun 8/166:11 am
IND
- TYS
1 stop6h 26m
American Airlines
Deal found 7/7![American Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:56 pm
TYS
- IND
1 stop21h 50m
Allegiant Air
Tue 10/610:00 am
IND
- TYS
1 stop5h 14m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$280
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:50 am
TYS
- IND
2 stops14h 45m
Southwest
Sun 8/236:00 am
IND
- TYS
1 stop8h 00m
Southwest
Deal found 7/7![Southwest logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:11 pm
TYS
- IND
1 stop13h 01m
Allegiant Air
Sun 8/29:22 pm
IND
- TYS
1 stop23h 53m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:00 am
TYS
- IND
1 stop17h 05m
Multiple Airlines
Mon 7/2712:20 pm
IND
- TYS
2 stops9h 40m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$295
Best flights from Knoxville to IndianapolisDiscover carefully curated flight deals from Knoxville to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
Discover carefully curated flight deals from Knoxville to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
TYS
- IND
1 stop4h 30m
Delta
Sat 9/51:41 pm
IND
- TYS
1 stop6h 29m
Delta
Deal found 7/8![Delta logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:00 am
TYS
- IND
1 stop17h 05m
Allegiant Air
Mon 7/277:00 am
IND
- TYS
1 stop27h 41m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$308
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:50 pm
TYS
- IND
1 stop9h 25m
Southwest
Tue 10/67:00 am
IND
- TYS
2 stops9h 40m
Southwest
Deal found 7/6![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:35 pm
TYS
- IND
1 stop4h 13m
United Airlines
Wed 12/97:00 am
IND
- TYS
1 stop6h 18m
United Airlines
Deal found 7/3![United Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:21 pm
TYS
- IND
1 stop6h 11m
Delta
Sun 11/86:00 am
IND
- TYS
1 stop5h 01m
Delta
Deal found 7/8![Delta logo]()
$279
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:40 am
TYS
- IND
1 stop3h 25m
Delta
Fri 8/71:41 pm
IND
- TYS
1 stop5h 11m
Delta
Deal found 7/8![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:50 am
TYS
- IND
2 stops12h 20m
Southwest
Sun 9/277:35 am
IND
- TYS
1 stop3h 20m
Southwest
Deal found 7/5![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/243:55 pm
TYS
- IND
1 stop5h 43m
Delta
Sun 11/296:25 pm
IND
- TYS
1 stop5h 21m
Delta
Deal found 7/6![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:00 am
TYS
- IND
2 stops9h 55m
Southwest
Sat 9/56:50 am
IND
- TYS
2 stops10h 50m
Southwest
Deal found 7/8![Southwest logo]()
$376
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:40 am
TYS
- IND
2 stops11h 25m
Southwest
Mon 8/34:05 pm
IND
- TYS
2 stops6h 30m
Southwest
Deal found 7/7![Southwest logo]()
$393
Last-minute flights from Knoxville to IndianapolisDiscover last-minute flight deals from Knoxville to Indianapolis. Data last updated July 8, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Indianapolis. Data last updated July 8, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:05 pm
TYS
- IND
1 stop25h 00m
Multiple Airlines
Mon 7/2012:20 pm
IND
- TYS
2 stops9h 40m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:00 am
TYS
- IND
1 stop17h 05m
Multiple Airlines
Mon 7/2712:20 pm
IND
- TYS
2 stops9h 40m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:00 am
TYS
- IND
1 stop17h 05m
Allegiant Air
Mon 7/277:00 am
IND
- TYS
1 stop27h 41m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:11 pm
TYS
- IND
2 stops14h 14m
Multiple Airlines
Sun 8/29:22 pm
IND
- TYS
1 stop23h 53m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:11 pm
TYS
- IND
1 stop13h 01m
Allegiant Air
Sun 8/29:22 pm
IND
- TYS
1 stop23h 53m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:20 pm
TYS
- IND
1 stop23h 42m
Multiple Airlines
Mon 8/312:20 pm
IND
- TYS
2 stops9h 40m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:40 am
TYS
- IND
1 stop3h 25m
Delta
Fri 8/71:41 pm
IND
- TYS
1 stop5h 11m
Delta
Deal found 7/8![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:12 pm
TYS
- IND
1 stop6h 15m
Delta
Thu 8/137:02 am
IND
- TYS
1 stop6h 32m
Delta
Deal found 7/8![Delta logo]()
$221
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 am
TYS
- IND
2 stops7h 40m
Southwest
Mon 8/176:55 am
IND
- TYS
1 stop5h 25m
Southwest
Deal found 7/7![Southwest logo]()
$228
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:25 pm
TYS
- IND
1 stop3h 48m
American Airlines
Sun 8/166:11 am
IND
- TYS
1 stop6h 26m
American Airlines
Deal found 7/7![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:50 am
TYS
- IND
2 stops14h 45m
Southwest
Sun 8/236:00 am
IND
- TYS
1 stop8h 00m
Southwest
Deal found 7/7![Southwest logo]()
$291
One-way flights from Knoxville to IndianapolisSearch for one-way flight options from Knoxville to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
Search for one-way flight options from Knoxville to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:56 pm
TYS
- IND
1 stop24h 58m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$146
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:00 am
TYS
- IND
2 stops9h 55m
Southwest
Deal found 7/6![Southwest logo]()
$174
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:00 am
TYS
- IND
1 stop5h 35m
American Airlines
Deal found 7/5![American Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:10 am
TYS
- IND
2 stops8h 20m
Southwest
Deal found 7/6![Southwest logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:11 pm
TYS
- IND
1 stop13h 01m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:20 pm
TYS
- IND
2 stops24h 48m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:20 pm
TYS
- IND
1 stop22h 55m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$231
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:54 pm
TYS
- IND
1 stop5h 07m
United Airlines
Deal found 7/8![United Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/291:05 pm
TYS
- IND
3 stops20h 58m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:57 am
TYS
- IND
1 stop5h 25m
Delta
Deal found 7/4![Delta logo]()
$314
Find flight deals from Knoxville to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $221 (Delta) |
One-way from | $146 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $258 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Knoxville to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Tue 9/1
6:00 am-10:30 am
1 stop4h 30m
Indianapolis
Sat 9/5
1:41 pm-8:10 pm
1 stop6h 29m
$221
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Thu 11/5
6:21 pm-12:32 am
1 stop6h 11m
Indianapolis
Sun 11/8
6:00 am-11:01 am
1 stop5h 01m
$279
Quickest round-trip
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Mon 8/3
5:40 am-9:05 am
1 stop3h 25m
Indianapolis
Fri 8/7
1:41 pm-6:52 pm
1 stop5h 11m
$299
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Sat 7/25
6:00 am-11:05 pm
1 stop17h 05m
Indianapolis
Mon 7/27
7:00 am-10:41 am
1 stop27h 41m
$308
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Fri 10/2
1:50 pm-11:15 pm
1 stop9h 25m
Indianapolis
Tue 10/6
7:00 am-4:40 pm
2 stops9h 40m
$311
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Tue 11/24
3:55 pm-9:38 pm
1 stop5h 43m
Indianapolis
Sun 11/29
6:25 pm-11:46 pm
1 stop5h 21m
$337
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Sat 9/26
7:50 am-8:10 pm
2 stops12h 20m
Indianapolis
Sun 9/27
7:35 am-10:55 am
1 stop3h 20m
$348
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Tue 9/1
7:00 am-4:55 pm
2 stops9h 55m
Indianapolis
Sat 9/5
6:50 am-5:40 pm
2 stops10h 50m
$376
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Tue 12/8
7:35 pm-11:48 pm
1 stop4h 13m
Indianapolis
Wed 12/9
7:00 am-1:18 pm
1 stop6h 18m
$385
KnoxvilleIndianapolis
TYS - IND
TYSIND
Knoxville McGhee Tyson
Fri 7/31
6:40 am-6:05 pm
2 stops11h 25m
Indianapolis
Mon 8/3
4:05 pm-10:35 pm
2 stops6h 30m
$393
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Indianapolis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Knoxville with our price prediction graph.
TYS-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Indianapolis
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated July 8, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
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Top 2 airlines flying from Knoxville to Indianapolis
Discover the top 2 airlines that operate flights from Knoxville to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$273 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$376 | FlexibilityNo cancel fee | On-timeN/A |