$137+ Cheap flights from Knoxville to Indianapolis (TYS - IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Dec 4 — Dec 111
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Indianapolis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to IndianapolisExplore the most affordable flight options available from Knoxville to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Knoxville to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:37 pm -
1 stop15h 47m
Mon 12/77:39 pm -
1 stop17h 28m
Deal found 11/3![Allegiant Air logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 am -
1 stop27h 31m
Tue 12/11:20 pm -
1 stop26h 59m
Deal found 11/2![Multiple Airlines logo]()
$266
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:17 pm -
1 stop3h 42m
Thu 12/176:00 am -
1 stop4h 01m
Deal found 11/4![Delta logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
2 stops28h 23m
Thu 11/196:30 am -
1 stop13h 46m
Deal found 10/31![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:49 pm -
1 stop22h 27m
Mon 11/232:56 pm -
1 stop5h 46m
Deal found 11/4![Allegiant Air logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:44 pm -
1 stop15h 59m
Thu 11/196:30 am -
1 stop13h 46m
Deal found 11/3![Allegiant Air logo]()
$300
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 am -
1 stop4h 27m
Fri 11/274:21 pm -
1 stop5h 51m
Deal found 11/2![Delta logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:36 am -
1 stop29h 44m
Mon 11/2310:56 am -
2 stops35h 10m
Deal found 11/4![Multiple Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 am -
1 stop4h 27m
Sat 11/286:00 am -
1 stop3h 55m
Deal found 11/2![Delta logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:26 am -
1 stop8h 17m
Thu 12/248:48 pm -
2 stops24h 30m
Deal found 11/2![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:11 pm -
1 stop14h 50m
Fri 11/2710:56 am -
1 stop27h 31m
Deal found 11/3![Multiple Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:20 am -
1 stop5h 53m
Mon 12/77:40 pm -
1 stop4h 19m
Deal found 11/3![United Airlines logo]()
$363
Best flights from Knoxville to IndianapolisDiscover carefully curated flight deals from Knoxville to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Knoxville to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:07 pm -
1 stop5h 50m
Sat 12/126:00 am -
1 stop3h 55m
Deal found 10/30![American Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:17 pm -
1 stop3h 42m
Thu 12/176:00 am -
1 stop4h 01m
Deal found 11/4![Delta logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
2 stops28h 23m
Thu 11/196:30 am -
1 stop13h 46m
Deal found 10/31![Multiple Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:55 am -
1 stop4h 10m
Thu 12/171:40 pm -
2 stops6h 55m
Deal found 11/1![Southwest logo]()
$373
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:44 am -
1 stop4h 40m
Thu 12/176:05 am -
1 stop4h 39m
Deal found 11/1![American Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:36 am -
1 stop29h 44m
Mon 11/2310:56 am -
2 stops35h 10m
Deal found 11/4![Multiple Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 am -
1 stop4h 27m
Sat 11/286:00 am -
1 stop3h 55m
Deal found 11/2![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:26 pm -
1 stop5h 26m
Sun 1/36:00 am -
1 stop5h 31m
Deal found 11/2![Delta logo]()
$380
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:05 am -
2 stops10h 25m
Mon 11/231:40 pm -
2 stops6h 55m
Deal found 11/4![Southwest logo]()
$518
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 pm -
2 stops15h 46m
Sat 11/285:40 am -
1 stop14h 34m
Deal found 11/3![Multiple Airlines logo]()
$503
Last-minute flights from Knoxville to IndianapolisDiscover last-minute flight deals from Knoxville to Indianapolis. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Indianapolis. Data last updated November 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
2 stops28h 23m
Thu 11/196:30 am -
1 stop13h 46m
Deal found 10/31![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:44 pm -
1 stop15h 59m
Thu 11/196:30 am -
1 stop13h 46m
Deal found 11/3![Allegiant Air logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:49 pm -
1 stop22h 27m
Mon 11/232:56 pm -
1 stop5h 46m
Deal found 11/4![Allegiant Air logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:36 am -
1 stop29h 44m
Mon 11/2310:56 am -
2 stops35h 10m
Deal found 11/4![Multiple Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 am -
1 stop4h 27m
Fri 11/274:21 pm -
1 stop5h 51m
Deal found 11/2![Delta logo]()
$326
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:40 am -
1 stop4h 27m
Sat 11/286:00 am -
1 stop3h 55m
Deal found 11/2![Delta logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:11 pm -
1 stop14h 50m
Fri 11/2710:56 am -
1 stop27h 31m
Deal found 11/3![Multiple Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 am -
1 stop27h 31m
Tue 12/11:20 pm -
1 stop26h 59m
Deal found 11/2![Multiple Airlines logo]()
$266
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:20 am -
1 stop5h 53m
Mon 12/77:40 pm -
1 stop4h 19m
Deal found 11/3![United Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:37 pm -
1 stop15h 47m
Mon 12/77:39 pm -
1 stop17h 28m
Deal found 11/3![Allegiant Air logo]()
$240
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:17 pm -
1 stop3h 42m
Thu 12/176:00 am -
1 stop4h 01m
Deal found 11/4![Delta logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:26 am -
1 stop8h 17m
Thu 12/248:48 pm -
2 stops24h 30m
Deal found 11/2![Multiple Airlines logo]()
$352
One-way flights from Knoxville to IndianapolisSearch for one-way flight options from Knoxville to Indianapolis. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Knoxville to Indianapolis. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:00 am -
1 stop3h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:02 am -
2 stops32h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:11 pm -
1 stop14h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:24 am -
2 stops29h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$179
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:45 am -
1 stop4h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2911:38 am -
3 stops54h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$238
Find flight deals from Knoxville to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $240 (Kiwi.com) |
One-way from | $137 (Delta) |
Popular in | January |
Cheapest in | October |
Average price | $506 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Knoxville to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Wed 12/9
7:00 am-10:38 am
1 stop3h 38m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Wed 12/9
11:02 am-7:32 pm
2 stops32h 30m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$141
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Tue 11/24
11:24 am-5:20 pm
2 stops29h 56m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Fri 11/27
5:45 am-10:20 am
1 stop4h 35m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Sun 11/29
11:38 am-6:32 pm
3 stops54h 54m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$238
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Mon 11/23
1:55 pm-7:22 pm
1 stop5h 27m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$244
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Mon 11/23
7:11 pm-9:24 pm
3 stops26h 13m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$261
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Fri 12/11
5:07 pm-10:57 pm
1 stop5h 50m
Indianapolis
Sat 12/12
6:00 am-9:55 am
1 stop3h 55m
$273
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Wed 12/9
6:17 pm-9:59 pm
1 stop3h 42m
Indianapolis
Thu 12/17
6:00 am-10:01 am
1 stop4h 01m
$273
KnoxvilleIndianapolis
TYS Knoxville McGhee Tyson - IND Indianapolis
TYSIND
Knoxville McGhee Tyson
Wed 12/9
7:44 am-12:24 pm
1 stop4h 40m
Indianapolis
Thu 12/17
6:05 am-10:44 am
1 stop4h 39m
$273
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Indianapolis in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Knoxville with our price prediction graph.
TYS-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated November 4, 2026.
Read reviews from past customers who have flown American Airlines from Knoxville to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Overall
7.0
Boarding
7.4
Entertainment
6.8
Crew
7.9
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Food
6.4
Overall
7.0
Boarding
7.4
Entertainment
6.8
Crew
7.9
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsPlainfield
Greenwood
Terre Haute
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Bloomington
Speedway
Noblesville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Indianapolis flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Indianapolis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indianapolis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Indianapolis by cabin class
Find flights from Knoxville to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Knoxville and Indianapolis flights
Browse other Knoxville and Indianapolis flight options. Last updated on November 4, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Knoxville to Indianapolis
Discover the top airline that operate flights from Knoxville to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$506 | FlexibilityNo cancel fee | On-time71% |