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$230+ Cheap flights from Biloxi, MS to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — IND
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Biloxi to Indianapolis

Cheapest flights from Biloxi to Indianapolis
Explore the most affordable flight options available from Biloxi to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:32 am
GPT
-
IND
1 stop4h 50m
American Airlines
Sun 2/154:20 pm
IND
-
GPT
1 stop7h 39m
American Airlines
Deal found 1/27$279
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:05 am
GPT
-
IND
1 stop5h 41m
Delta
Sat 2/76:43 pm
IND
-
GPT
1 stop4h 10m
Delta
Deal found 1/27$339
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:45 pm
GPT
-
IND
1 stop4h 44m
American Airlines
Sat 2/72:22 pm
IND
-
GPT
2 stops9h 46m
American Airlines
Deal found 1/27$344
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 pm
GPT
-
IND
1 stop5h 14m
Delta
Fri 6/194:15 pm
IND
-
GPT
1 stop6h 52m
Delta
Deal found 1/26$354
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 pm
GPT
-
IND
1 stop5h 32m
Delta
Sun 10/188:25 am
IND
-
GPT
1 stop6h 10m
Delta
Deal found 1/27$379
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:00 pm
GPT
-
IND
1 stop4h 47m
United Airlines
Wed 11/46:00 am
IND
-
GPT
2 stops8h 26m
United Airlines
Deal found 1/26$414
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:20 pm
GPT
-
IND
2 stops26h 55m
Multiple Airlines
Sun 3/229:07 am
IND
-
GPT
1 stop10h 33m
Multiple Airlines
Deal found 1/27$416
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/194:29 pm
GPT
-
IND
1 stop7h 12m
American Airlines
Sun 3/224:20 pm
IND
-
GPT
1 stop7h 39m
American Airlines
Deal found 1/27$433

Find flight deals from Biloxi to Indianapolis

Keep the following information in mind while searching for Biloxi to Indianapolis flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(American Airlines)

One-way from

$230
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$253
Provider with most accurate pricing for Gulfport Biloxi Regional-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Indianapolis flights.
Search Deals
From Biloxi to Indianapolis
Search Deals
One-way flight from Biloxi to Indianapolis
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Biloxi to Indianapolis that are best for you.

Fly from

Biloxi

Fly to

Indianapolis

Route

Depart

Return

Price

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Wed 2/11

6:32 am-12:22 pm

1 stop4h 50m

Indianapolis

Sun 2/15

4:20 pm-10:59 pm

1 stop7h 39m

$279

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Wed 6/10

5:15 pm-11:25 pm

1 stop5h 10m

Indianapolis

Fri 6/19

7:01 am-4:02 pm

2 stops10h 01m

$344

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Wed 6/10

6:00 pm-12:14 am

1 stop5h 14m

Indianapolis

Fri 6/19

4:15 pm-10:07 pm

1 stop6h 52m

$354

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Thu 3/19

7:20 pm-11:15 pm

2 stops26h 55m

Indianapolis

Sun 3/22

9:07 am-6:40 pm

1 stop10h 33m

$416

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Thu 3/19

4:29 pm-12:41 am

1 stop7h 12m

Indianapolis

Sun 3/22

4:20 pm-10:59 pm

1 stop7h 39m

$433

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Thu 3/19

2:00 pm-11:59 pm

2 stops8h 59m

Indianapolis

Sun 3/22

6:00 am-1:25 pm

2 stops8h 25m

$673

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Mon 2/2

6:54 pm-10:48 pm

2 stops26h 54m

$230

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Mon 2/2

2:40 pm-9:29 pm

1 stop5h 49m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Biloxi to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Indianapolis

What is the cheapest month to book a flight from Biloxi to Indianapolis?

Currently, February is the cheapest month in which you can book a flight from Biloxi to Indianapolis (average of $51). Flying from Biloxi to Indianapolis in May is currently the most expensive (average of $134). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated January 28, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Biloxi to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,123 reviews
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Biloxi?

    Indianapolis (IND), located 8.3 mi from the city center, is the airport you fly into when you book flights from Biloxi to Indianapolis. 5 airlines have flights to Indianapolis from Biloxi on a regular basis. Booking flights from Biloxi to Indianapolis should not be difficult; the airport handles an average of 0 inbound flights from Biloxi per day.

  • How long is the flight from Biloxi to Indianapolis?

    A quick flight from Biloxi to Indianapolis can take about 4h 50m. American Airlines provides one of the quickest options available for as low as $279. The distance from Biloxi to Indianapolis is about 661 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Biloxi to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Biloxi to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Indianapolis.

  • Can I find deals for business class flights from Biloxi to Indianapolis?

    Yes. Cheapflights offers flight deals from Biloxi to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Indianapolis?

    Currently, February is the cheapest month in which you can book a flight from Biloxi to Indianapolis (average of $51). Flying from Biloxi to Indianapolis in May is currently the most expensive (average of $134). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Anderson
Kokomo
Mooresville
Franklin
Carmel
Crawfordsville
Bloomington

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Biloxi to Indianapolis

Discover the top 5 airlines that operate flights from Biloxi to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$101Average$213FlexibilityNo cancel feeOn-time65%
DeltaCheapest$172Average$336FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$214Average$487FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$226Average$358FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$266Average$366FlexibilityNo cancel feeOn-time63%

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