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Illinois

$207+ Cheap flights from Panama to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — ORD
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Panama to Illinois

Keep the following information in mind while searching for Panama to Illinois flight deals. Data was last updated September 17, 2025.

Round-trip from

$404
(Kiwi.com)

One-way from

$207
(Mytrip)

Popular in

March

Cheapest in

July

Average price

$531

Good round-trip deal

$433 or less

Good one-way deal

$722 or less
From Panama to Illinois
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One-way flight from Panama to Illinois
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High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Panama to Illinois.
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Price to beat on a one-way flight from Panama to Illinois.
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Find flight deals from Panama to Illinois

Cheapest flights from Panama to Illinois
Explore the most affordable flight options available from Panama to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:55 pmPTY - ORD
2 stops18h 27mMultiple Airlines
Thu 11/610:20 pmORD - PTY
1 stop9h 30mMultiple Airlines
Deal found 9/15$404
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:20 pmPTY - ORD
Nonstop5h 45mCopa Airlines
Wed 11/56:56 amORD - PTY
Nonstop5h 26mCopa Airlines
Deal found 9/16$418
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:35 pmPTY - ORD
2 stops18h 47mMultiple Airlines
Wed 11/58:50 pmORD - PTY
3 stops27h 10mMultiple Airlines
Deal found 9/16$420
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/32:10 pmPTY - MDW
2 stops18h 30mDelta
Tue 10/76:00 amMDW - PTY
1 stop6h 56mDelta
Deal found 9/16$423
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2410:00 amPTY - ORD
1 stop12h 37mUnited Airlines
Mon 10/277:55 pmORD - PTY
1 stop22h 43mUnited Airlines
Deal found 9/15$423
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/292:55 amPTY - ORD
1 stop18h 25mAvianca
Thu 11/610:20 pmORD - PTY
1 stop17h 35mAvianca
Deal found 9/15$427
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1510:05 pmPTY - ORD
2 stops35h 17mMultiple Airlines
Wed 10/222:35 pmORD - PTY
1 stop10h 10mMultiple Airlines
Deal found 9/17$432
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:43 pmPTY - ORD
1 stop22h 21mAmerican Airlines
Sun 12/75:00 amORD - PTY
1 stop7h 47mAmerican Airlines
Deal found 9/16$434
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/293:31 pmPTY - ORD
1 stop17h 09mAmerican Airlines
Sun 10/55:00 amORD - PTY
1 stop9h 31mAmerican Airlines
Deal found 9/15$436
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/163:15 pmPTY - ORD
1 stop8h 43mAmerican Airlines
Mon 10/208:44 pmORD - PTY
2 stops17h 19mAmerican Airlines
Deal found 9/14$437
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/169:33 pmPTY - MDW
1 stop12h 00mMultiple Airlines
Mon 10/2010:33 amMDW - PTY
1 stop8h 56mMultiple Airlines
Deal found 9/14$462
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:21 pmPTY - MDW
1 stop7h 53mDelta
Wed 11/56:00 amMDW - PTY
1 stop6h 56mDelta
Deal found 9/17$523

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama to Illinois that are best for you.

Fly from

Panama

Fly to

Illinois

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 11/1

7:20 pm-1:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Thu 11/6

2:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 10/16

6:45 pm-12:21 am

Nonstop5h 36m

Chicago O'Hare Intl

Mon 10/20

3:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 11/1

7:20 pm-1:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Wed 11/5

6:56 am-1:22 pm

Nonstop5h 26m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 10/25

6:45 pm-12:21 am

Nonstop5h 36m

Chicago O'Hare Intl

Tue 11/11

2:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 11/21

7:20 pm-12:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Sun 12/7

2:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 10/27

7:20 pm-12:56 am

Nonstop5h 36m

Chicago O'Hare Intl

Fri 10/31

3:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 10/24

6:45 pm-12:21 am

Nonstop5h 36m

Chicago O'Hare Intl

Tue 11/11

6:56 am-1:22 pm

Nonstop5h 26m

$418

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Fri 10/3

2:10 pm-8:40 am

2 stops18h 30m

Chicago Midway

Tue 10/7

6:00 am-12:56 pm

1 stop6h 56m

$423

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 10/16

9:33 pm-9:33 am

1 stop12h 00m

Chicago Midway

Mon 10/20

10:33 am-7:29 pm

1 stop8h 56m

$462

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 2/3

8:55 am-3:52 pm

1 stop7h 57m

Lambert-St Louis

Tue 3/3

6:45 pm-5:07 pm

2 stops21h 22m

$515

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 39 results
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Best time to book a flight from Panama to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Illinois

What is the cheapest month to book a flight from Panama to Illinois?

Currently, August is the cheapest month in which you can book a flight from Panama to Illinois (average of $245). Flying from Panama to Illinois in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IL?

Find hourly flight availability from Panama to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Illinois as you normally would.

Weekly flight availability from Panama to Illinois

Explore weekly flight availability from Panama to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2025.

The most flights from PA0 to USIL are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated September 17, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and Avianca from Panama to Illinois to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Copa Airlines
7.6
Good
1,533 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Avianca
6.7
Okay
2,436 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Panama to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Illinois?

    Airlines like Copa Airlines, Delta, and United Airlines fly from Panama to Illinois in about 5h 45m. The time it takes to get you to your destination can typically vary by up to 12h 45m. Panama and Illinois are separated by a distance of 2330 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Panama to Illinois that include hotel bookings?

    Yes. In addition to deals on Panama to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Illinois.

  • Can I find deals for business class flights from Panama to Illinois?

    Yes. Cheapflights offers flight deals from Panama to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Illinois?

    Currently, August is the cheapest month in which you can book a flight from Panama to Illinois (average of $245). Flying from Panama to Illinois in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Illinois

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Illinois

Discover the top 2 airlines that operate flights from Panama to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$415Average$558FlexibilityNo cancel feeOn-time70%
DeltaCheapest$598Average$673FlexibilityNo cancel feeOn-timeN/A

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