HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Illinois

$240+ Cheap flights from Panama to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — ORD
mar. 20 — mar. 271
vie. 3/20
vie. 3/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama to Illinois with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama to Illinois

Cheapest flights from Panama to Illinois
Explore the most affordable flight options available from Panama to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/289:33 pm
PTY
-
ORD
2 stops17h 03m
Multiple Airlines
vie. 5/811:20 pm
ORD
-
PTY
1 stop9h 55m
Multiple Airlines
Deal found 2/17$417
This Trip.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/159:45 am
PTY
-
ORD
2 stops22h 40m
Multiple Airlines
mar. 3/3110:55 am
ORD
-
PTY
3 stops15h 00m
Multiple Airlines
Deal found 2/15$435
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/25:30 am
PTY
-
ORD
3 stops24h 22m
Multiple Airlines
dom. 5/1011:20 pm
ORD
-
PTY
1 stop14h 55m
Multiple Airlines
Deal found 2/17$448
This Trip.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/210:10 am
PTY
-
ORD
1 stop11h 10m
Avianca
dom. 5/1011:20 pm
ORD
-
PTY
1 stop14h 55m
Avianca
Deal found 2/17$451
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/239:45 am
PTY
-
ORD
2 stops24h 54m
Multiple Airlines
lun. 3/29:18 am
ORD
-
PTY
2 stops27h 42m
Multiple Airlines
Deal found 2/17$472
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/313:10 pm
PTY
-
ORD
2 stops18h 40m
Multiple Airlines
mar. 4/74:51 pm
ORD
-
PTY
1 stop15h 39m
Multiple Airlines
Deal found 2/14$492
This Mytrip deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/25:50 pm
PTY
-
ORD
2 stops16h 49m
Multiple Airlines
jue. 3/57:23 pm
ORD
-
PTY
2 stops12h 27m
Multiple Airlines
Deal found 2/16$499
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/83:10 pm
PTY
-
ORD
2 stops19h 40m
Multiple Airlines
mar. 5/1911:20 pm
ORD
-
PTY
1 stop14h 55m
Multiple Airlines
Deal found 2/17$509
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/1510:00 am
PTY
-
STL
2 stops12h 56m
United Airlines
vie. 5/157:45 am
STL
-
PTY
2 stops10h 52m
United Airlines
Deal found 2/15$570
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/303:30 pm
PTY
-
STL
2 stops24h 16m
United Airlines
mar. 6/25:41 pm
STL
-
PTY
2 stops22h 31m
United Airlines
Deal found 2/16$584
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/151:49 pm
PTY
-
STL
1 stop8h 35m
American Airlines
vie. 5/155:24 am
STL
-
PTY
1 stop7h 22m
American Airlines
Deal found 2/15$587
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/173:10 pm
PTY
-
STL
2 stops17h 45m
American Airlines
mar. 3/245:15 am
STL
-
PTY
1 stop9h 05m
American Airlines
Deal found 2/17$591

Find flight deals from Panama to Illinois

Keep the following information in mind while searching for Panama to Illinois flight deals. Data was last updated febrero 18, 2026.

Round-trip from

$417
(Kiwi.com)

One-way from

$240
(Trip.com)

Popular in

January

Cheapest in

July

Average price

$580

Good round-trip deal

$887 or less

Good one-way deal

$596 or less
From Panama to Illinois
Search Deals
One-way flight from Panama to Illinois
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Panama to Illinois.
Search Deals
Price to beat on a one-way flight from Panama to Illinois.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 18, 2026.
Use the filters below to find and compare flights from Panama to Illinois that are best for you.

Fly from

Panama

Fly to

Illinois

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

dom. 3/15

9:45 am-8:25 am

2 stops22h 40m

Chicago O'Hare Intl

mar. 3/31

10:55 am-1:55 am

3 stops15h 00m

$435

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

vie. 5/8

10:10 am-9:20 pm

1 stop11h 10m

Chicago O'Hare Intl

mar. 5/19

11:20 pm-2:15 pm

1 stop14h 55m

$451

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

jue. 5/7

3:25 am-5:52 am

3 stops26h 27m

Chicago O'Hare Intl

mar. 5/19

11:20 pm-9:15 am

1 stop9h 55m

$472

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

lun. 3/2

5:50 pm-9:39 am

2 stops16h 49m

Chicago O'Hare Intl

jue. 3/5

7:23 pm-8:50 am

2 stops12h 27m

$499

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

lun. 3/2

5:50 pm-9:39 am

2 stops16h 49m

Chicago O'Hare Intl

jue. 4/2

4:51 pm-5:00 pm

2 stops24h 09m

$523

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

mar. 3/31

9:33 pm-9:50 am

1 stop12h 17m

Chicago O'Hare Intl

mar. 4/7

4:51 pm-8:06 am

1 stop15h 15m

$537

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

mar. 5/19

3:25 am-9:17 pm

2 stops17h 52m

Chicago O'Hare Intl

mié. 5/27

11:20 pm-9:15 am

1 stop9h 55m

$563

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mié. 4/15

10:00 am-10:56 pm

2 stops12h 56m

Lambert-St Louis

vie. 5/15

7:45 am-6:37 pm

2 stops10h 52m

$570

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

mié. 5/20

7:25 pm-1:15 am

Nonstop5h 50m

Chicago O'Hare Intl

mié. 5/27

8:02 am-1:22 pm

Nonstop5h 20m

$576

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

mié. 5/20

10:10 am-9:20 pm

1 stop11h 10m

Chicago O'Hare Intl

dom. 5/24

11:20 pm-5:00 pm

1 stop17h 40m

$580

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/16

Showing 1-10 of 40 results
1
2
3
4

Best time to book a flight from Panama to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Illinois

What is the cheapest month to book a flight from Panama to Illinois?

Currently, October is the cheapest month in which you can book a flight from Panama to Illinois (average of $239). Flying from Panama to Illinois in May is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IL?

Find hourly flight availability from Panama to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 18, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Illinois as you normally would.

Weekly flight availability from Panama to Illinois

Explore weekly flight availability from Panama to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated febrero 18, 2026.

The most flights from PA0 to USIL are scheduled on a Monday (5 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated febrero 18, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Panama to Illinois to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,556 reviews

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.5
Good
1,556 reviews
Copa Airlines
7.5
Good
1,556 reviews

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
United Airlines
7.4
Good
9,314 reviews
Copa Airlines
7.5
Good
1,556 reviews

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Panama to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Illinois?

    Airlines like Avianca and United Airlines fly from Panama to Illinois in about 11h 10m. The time it takes to get you to your destination can typically vary by up to 1h 46m. Panama and Illinois are separated by a distance of 2330 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Panama to Illinois one-way?

    The cheapest airlines for a one-way flight from Panama to Illinois are Avianca ($175), Copa Airlines ($255), and United Airlines ($444).

  • Can I find deals for flights from Panama to Illinois that include hotel bookings?

    Yes. In addition to deals on Panama to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Illinois.

  • Can I find deals for business class flights from Panama to Illinois?

    Yes. Cheapflights offers flight deals from Panama to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Illinois?

    Currently, October is the cheapest month in which you can book a flight from Panama to Illinois (average of $239). Flying from Panama to Illinois in May is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to Illinois

See prices for flight routes from nearby airports that may be better suited for you.
San José to Newark flights
San José to John F Kennedy Intl flights
San José to Miami flights
San José to Orlando flights
San José to Fort Lauderdale flights
Panama City to John F Kennedy Intl flights
Guatemala City to Miami flights
Guatemala City to John F Kennedy Intl flights
San José to Los Angeles flights
San Salvador to Los Angeles flights
Guatemala City to Los Angeles flights
San Pedro Sula to Hobby flights
Panama City to Miami flights
San Salvador to Miami flights
Guatemala City to Hobby flights
Panama City to Newark flights
Guatemala City to Fort Lauderdale flights
San Pedro Sula to George Bush Intcntl flights
San José to LaGuardia flights
Guatemala City to George Bush Intcntl flights
San Salvador to Hobby flights
San Salvador to George Bush Intcntl flights
Guatemala City to Newark flights
San José to Hobby flights
Guatemala City to Atlanta flights
Guatemala City to Orlando flights
San José to George Bush Intcntl flights
San José to Las Vegas flights
San Pedro Sula to Miami flights
San Pedro Sula to John F Kennedy Intl flights
San José to Atlanta flights
Panama City to LaGuardia flights
Guatemala City to LaGuardia flights
San Salvador to Dulles Intl flights
San Salvador to John F Kennedy Intl flights
Guatemala City to Dulles Intl flights
Panama City to Orlando flights
San Pedro Sula to Atlanta flights
Guatemala City to Dallas/Fort Worth flights
Managua to Miami flights
San José to Dallas/Fort Worth flights
San José to O'Hare Intl flights
Guatemala City to Ontario flights
San Salvador to Atlanta flights
San José to San Francisco flights
San Salvador to Dallas/Fort Worth flights
San José to Dulles Intl flights
Guatemala City to O'Hare Intl flights
San Salvador to Ontario flights
San Pedro Sula to Newark flights

Top 2 airlines flying from Panama to Illinois

Discover the top 2 airlines that operate flights from Panama to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$405Average$581FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$423Average$485FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.