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Illinois

$259+ Cheap flights from Panama to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — ORD
dic. 13 — dic. 201
sáb. 12/13
sáb. 12/20
1 adult, Economy
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Cheap flight deals from Panama to Illinois

Keep the following information in mind while searching for Panama to Illinois flight deals. Data was last updated noviembre 13, 2025.

Round-trip from

$515
(Mytrip)

One-way from

$259
(Kiwi.com)

Popular in

March

Cheapest in

July

Average price

$514

Good round-trip deal

$533 or less

Good one-way deal

$574 or less
From Panama to Illinois
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One-way flight from Panama to Illinois
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Panama to Illinois.
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Price to beat on a one-way flight from Panama to Illinois.
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Find flight deals from Panama to Illinois

Cheapest flights from Panama to Illinois
Explore the most affordable flight options available from Panama to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 13, 2025.

This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/2411:25 amPTY - ORD
2 stops12h 48mMultiple Airlines
dom. 11/3010:20 pmORD - PTY
1 stop9h 30mMultiple Airlines
Deal found 11/11$515
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/242:55 pmPTY - ORD
1 stop14h 41mMultiple Airlines
mié. 1/76:05 pmORD - PTY
2 stops23h 50mMultiple Airlines
Deal found 11/10$517
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/168:55 amPTY - STL
1 stop8h 09mUnited Airlines
mar. 2/1010:07 amSTL - PTY
1 stop8h 31mUnited Airlines
Deal found 11/12$537
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/55:50 pmPTY - ORD
2 stops31h 19mMultiple Airlines
mié. 12/105:00 amORD - PTY
2 stops26h 50mMultiple Airlines
Deal found 11/12$549
This Cheapflightsfares deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/192:55 amPTY - ORD
1 stop18h 25mAvianca
lun. 11/2410:20 pmORD - PTY
1 stop17h 35mAvianca
Deal found 11/12$555
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/294:41 pmPTY - STL
1 stop30h 14mUnited Airlines
sáb. 1/104:35 pmSTL - PTY
1 stop23h 32mUnited Airlines
Deal found 11/12$558
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/262:55 amPTY - ORD
1 stop18h 25mAvianca
dom. 11/3010:20 pmORD - PTY
1 stop17h 35mAvianca
Deal found 11/11$563
This Cheapflightsfares deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/142:55 amPTY - ORD
1 stop18h 25mAvianca
mar. 11/1810:20 pmORD - PTY
1 stop9h 30mAvianca
Deal found 11/11$576
This Cheapflightsfares deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/292:55 amPTY - ORD
1 stop18h 25mAvianca
vie. 1/910:20 pmORD - PTY
1 stop17h 35mAvianca
Deal found 11/12$579
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/292:53 pmPTY - STL
1 stop8h 42mAmerican Airlines
sáb. 1/1010:00 amSTL - PTY
1 stop26h 27mAmerican Airlines
Deal found 11/12$600
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/274:41 pmPTY - STL
2 stops22h 43mUnited Airlines
dom. 11/306:15 amSTL - PTY
1 stop7h 30mUnited Airlines
Deal found 11/13$623
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/238:00 amPTY - MDW
1 stop9h 20mDelta
vie. 1/26:00 amMDW - PTY
1 stop13h 00mDelta
Deal found 11/13$623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 13, 2025.
Use the filters below to find and compare flights from Panama to Illinois that are best for you.

Fly from

Panama

Fly to

Illinois

Route

Depart

Return

Price

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mié. 12/17

10:00 am-10:45 pm

2 stops13h 45m

Lambert-St Louis

mié. 2/11

6:00 am-2:45 pm

1 stop7h 45m

$537

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mar. 12/16

4:41 pm-12:15 pm

2 stops20h 34m

Lambert-St Louis

mar. 2/10

6:00 am-5:07 pm

1 stop10h 07m

$537

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

lun. 1/12

4:50 pm-11:03 am

2 stops19h 13m

Lambert-St Louis

lun. 1/19

3:54 pm-1:27 pm

2 stops20h 33m

$551

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

lun. 12/29

4:41 pm-4:36 pm

1 stop24h 55m

Lambert-St Louis

sáb. 1/10

4:35 pm-2:45 pm

1 stop21h 10m

$558

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

sáb. 12/27

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

vie. 1/9

10:20 pm-4:55 pm

1 stop17h 35m

$579

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

sáb. 5/2

5:25 pm-1:15 pm

1 stop19h 50m

Chicago O'Hare Intl

dom. 5/10

2:35 pm-10:10 am

1 stop19h 35m

$579

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

dom. 2/1

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

vie. 2/6

10:20 pm-8:50 am

1 stop9h 30m

$579

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

sáb. 3/7

7:20 pm-12:04 am

Nonstop5h 44m

Chicago O'Hare Intl

mar. 3/10

3:22 pm-8:35 pm

Nonstop5h 13m

$580

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

dom. 3/1

7:20 pm-12:04 am

Nonstop5h 44m

Chicago O'Hare Intl

jue. 4/30

3:13 pm-8:35 pm

Nonstop5h 22m

$580

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

jue. 2/12

7:55 am-12:31 pm

Nonstop5h 36m

Chicago O'Hare Intl

mar. 2/17

7:34 am-2:00 pm

Nonstop5h 26m

$580

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 36 results
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Best time to book a flight from Panama to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Illinois

What is the cheapest month to book a flight from Panama to Illinois?

Currently, October is the cheapest month in which you can book a flight from Panama to Illinois (average of $239). Flying from Panama to Illinois in April is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IL?

Find hourly flight availability from Panama to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 13, 2025.

When flying from Panama to Illinois, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 19% versus a flight at noon.

Weekly flight availability from Panama to Illinois

Explore weekly flight availability from Panama to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated noviembre 13, 2025.

The most flights from PA0 to USIL are scheduled on a Wednesday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated noviembre 13, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Panama to Illinois to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,565 reviews

Comfort

7.4

Entertainment

6.8

Food

6.9

Boarding

7.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,565 reviews
Copa Airlines
7.6
Good
1,565 reviews

Comfort

7.4

Entertainment

6.8

Food

6.9

Boarding

7.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,476 reviews
Copa Airlines
7.6
Good
1,565 reviews

Comfort

7.4

Entertainment

6.8

Food

6.9

Boarding

7.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Illinois?

    Airlines like United Airlines, Avianca, and Copa Airlines fly from Panama to Illinois in about 5h 44m. The time it takes to get you to your destination can typically vary by up to 12h 41m. Panama and Illinois are separated by a distance of 2330 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Panama to Illinois one-way?

    The cheapest airlines for a one-way flight from Panama to Illinois are Avianca ($304), United Airlines ($312), and American Airlines ($317).

  • Can I find deals for flights from Panama to Illinois that include hotel bookings?

    Yes. In addition to deals on Panama to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Illinois.

  • Can I find deals for business class flights from Panama to Illinois?

    Yes. Cheapflights offers flight deals from Panama to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Illinois?

    Currently, October is the cheapest month in which you can book a flight from Panama to Illinois (average of $239). Flying from Panama to Illinois in April is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Illinois

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama to Illinois

Discover the top airline that operate flights from Panama to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$415Average$586FlexibilityNo cancel feeOn-time70%

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