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Guayaquil

$162+ Cheap flights from Santo Domingo (SDQ) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — GYE
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo are usually found in August or September, booked 45 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Santo Domingo to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$437
(Copa Airlines)

One-way from

$162
(Arajet)

Popular in

March

Cheapest in

August

Average price

$410
From Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santo Domingo to Guayaquil

Cheapest flights from Santo Domingo to Guayaquil
Explore the most affordable flight options available from Santo Domingo to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:55 amSDQ - GYE
1 stop5h 39mCopa Airlines
Fri 11/286:35 pmGYE - SDQ
1 stop15h 23mCopa Airlines
Deal found 7/1$437
This Avianca deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/86:10 pmSDQ - GYE
1 stop6h 10mAvianca
Mon 8/113:35 amGYE - SDQ
1 stop6h 15mAvianca
Deal found 7/1$448
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/219:00 pmSDQ - GYE
3 stops21h 55mMultiple Airlines
Sun 9/73:35 amGYE - SDQ
1 stop6h 15mMultiple Airlines
Deal found 7/1$675
This JetBlue deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/19:30 pmSDQ - GYE
1 stop14h 09mJetBlue
Fri 9/269:30 pmGYE - SDQ
1 stop18h 25mJetBlue
Deal found 7/2$839

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Santo Domingo to Guayaquil that are best for you.

Fly from

Santo Domingo

Fly to

Guayaquil

Route

Depart

Return

Price

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Fri 11/7

8:55 am-1:34 pm

1 stop5h 39m

Guayaquil Jose Joaquin de Olmedo

Fri 11/28

6:35 pm-10:58 am

1 stop15h 23m

$437

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Fri 8/8

6:10 pm-11:20 pm

1 stop6h 10m

Guayaquil Jose Joaquin de Olmedo

Mon 8/11

3:35 am-10:50 am

1 stop6h 15m

$448

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Thu 8/21

9:00 pm-5:55 pm

3 stops21h 55m

Guayaquil Jose Joaquin de Olmedo

Sun 9/7

3:35 am-10:50 am

1 stop6h 15m

$675

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Fri 8/1

9:30 pm-10:39 am

1 stop14h 09m

Guayaquil Jose Joaquin de Olmedo

Fri 9/26

9:30 pm-4:55 pm

1 stop18h 25m

$839

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Sun 8/3

1:55 pm-1:57 am

1 stop13h 02m

$162

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Mon 8/18

11:45 am-5:20 pm

1 stop6h 35m

$205

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Mon 8/11

11:54 am-11:37 pm

1 stop12h 43m

$216

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Santo Domingo to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Guayaquil

How far ahead should I book a flight from Santo Domingo to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Guayaquil. Price data was last updated on June 27, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Guayaquil, you should look to book at least 45 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Guayaquil (average of $440). Flying from Santo Domingo to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to GYE?

Find hourly flight availability from Santo Domingo to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

When flying from Santo Domingo to Guayaquil, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 30% versus a flight in the morning.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated July 3, 2025.
Read reviews from past customers who have flown Copa Airlines, JetBlue, and Avianca from Santo Domingo to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,467 reviews

Entertainment

6.8

Crew

8.1

Food

6.8

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,467 reviews
Copa Airlines
7.5
Good
1,467 reviews

Entertainment

6.8

Crew

8.1

Food

6.8

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
JetBlue
7.3
Good
2,916 reviews
Copa Airlines
7.5
Good
1,467 reviews

Entertainment

6.8

Crew

8.1

Food

6.8

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,363 reviews
Copa Airlines
7.5
Good
1,467 reviews

Entertainment

6.8

Crew

8.1

Food

6.8

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to Guayaquil round-trip?

    According to our current data, Copa Airlines ($437), Avianca ($448), and JetBlue ($839) offers the cheapest pricing from Santo Domingo to Guayaquil.

  • Can I find deals for flights from Santo Domingo to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Guayaquil.

  • Can I find deals for business class flights from Santo Domingo to Guayaquil?

    Yes. Cheapflights offers flight deals from Santo Domingo to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Guayaquil (average of $440). Flying from Santo Domingo to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to Guayaquil

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Top 2 airlines flying from Santo Domingo to Guayaquil

Discover the top 2 airlines that operate flights from Santo Domingo to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$344Average$430FlexibilityNo cancel feeOn-time70%
AviancaCheapest$372Average$420FlexibilityNo cancel feeOn-time71%

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