$191+ Cheap flights from San Francisco (SFO) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GYE
Apr 12 — Apr 191
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Francisco to GuayaquilExplore the most affordable flight options available from San Francisco to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from San Francisco to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/261:23 am
SFO
- GYE
1 stop10h 12m
Copa Airlines
Thu 4/308:28 am
GYE
- SFO
1 stop17h 12m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$419
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/261:23 am
SFO
- GYE
1 stop10h 12m
Copa Airlines
Thu 5/78:28 am
GYE
- SFO
1 stop17h 12m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$440
This Cheapflightsfares deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Tue 4/2812:25 pm
GYE
- SFO
1 stop13h 31m
JetBlue
Deal found 3/10![JetBlue logo]()
$447
This JetBlue deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Wed 4/223:51 pm
GYE
- SFO
1 stop19h 32m
JetBlue
Deal found 3/10![JetBlue logo]()
$452
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:12 am
SFO
- GYE
1 stop20h 49m
Copa Airlines
Sun 10/256:02 am
GYE
- SFO
1 stop14h 08m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$456
This Copa Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:12 am
SFO
- GYE
1 stop20h 49m
Copa Airlines
Thu 10/154:30 am
GYE
- SFO
1 stop21h 10m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$457
This Justfly.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Mon 4/206:50 pm
GYE
- SFO
2 stops31h 05m
Avianca
Deal found 3/9![Avianca logo]()
$461
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Wed 4/226:50 pm
GYE
- SFO
2 stops29h 45m
Avianca
Deal found 3/8![Avianca logo]()
$473
This SmartFares deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Mon 4/273:51 pm
GYE
- SFO
1 stop19h 32m
JetBlue
Deal found 3/10![JetBlue logo]()
$477
This Copa Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/161:12 am
SFO
- GYE
1 stop20h 50m
Copa Airlines
Thu 8/2011:48 am
GYE
- SFO
1 stop13h 52m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$478
This Justfly.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Mon 5/43:45 pm
GYE
- SFO
2 stops23h 05m
Avianca
Deal found 3/10![Avianca logo]()
$485
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:15 am
SFO
- GYE
1 stop12h 57m
American Airlines
Fri 5/16:05 am
GYE
- SFO
1 stop19h 54m
American Airlines
Deal found 3/9![American Airlines logo]()
$495
Best flights from San Francisco to GuayaquilDiscover carefully curated flight deals from San Francisco to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from San Francisco to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/261:23 am
SFO
- GYE
1 stop10h 12m
Copa Airlines
Thu 4/308:28 am
GYE
- SFO
1 stop17h 12m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$419
This Avianca deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Wed 4/226:50 pm
GYE
- SFO
2 stops20h 00m
Avianca
Deal found 3/7![Avianca logo]()
$473
This JetBlue deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Wed 4/223:51 pm
GYE
- SFO
1 stop19h 32m
JetBlue
Deal found 3/9![JetBlue logo]()
$526
This BusinessClass deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:28 pm
SFO
- GYE
2 stops20h 44m
GOL
Sun 5/176:05 am
GYE
- SFO
1 stop18h 56m
GOL
Deal found 3/10![GOL logo]()
$602
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/612:45 am
SFO
- GYE
2 stops14h 46m
United Airlines
Fri 4/178:28 am
GYE
- SFO
2 stops17h 31m
United Airlines
Deal found 3/9![United Airlines logo]()
$609
This Copa Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/161:12 am
SFO
- GYE
1 stop20h 50m
Copa Airlines
Thu 8/2011:48 am
GYE
- SFO
1 stop13h 52m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$478
This Copa Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/191:23 am
SFO
- GYE
1 stop20h 15m
Copa Airlines
Mon 5/412:22 pm
GYE
- SFO
1 stop13h 18m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$514
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/612:45 am
SFO
- GYE
2 stops14h 46m
United Airlines
Sat 4/1812:22 pm
GYE
- SFO
2 stops20h 54m
United Airlines
Deal found 3/9![United Airlines logo]()
$609
This Justfly.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:55 pm
SFO
- GYE
2 stops31h 00m
Avianca
Sat 4/189:10 am
GYE
- SFO
2 stops29h 40m
Avianca
Deal found 3/10![Avianca logo]()
$638
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:59 pm
SFO
- GYE
2 stops18h 54m
United Airlines
Thu 8/2012:22 pm
GYE
- SFO
2 stops13h 54m
United Airlines
Deal found 3/12![United Airlines logo]()
$649
Last-minute flights from San Francisco to GuayaquilDiscover last-minute flight deals from San Francisco to Guayaquil. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Guayaquil. Data last updated March 13, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:59 pm
SFO
- GYE
1 stop12h 41m
JetBlue
Mon 4/203:51 pm
GYE
- SFO
1 stop19h 32m
JetBlue
Deal found 3/9![JetBlue logo]()
$507
This Justfly.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Mon 4/206:50 pm
GYE
- SFO
2 stops31h 05m
Avianca
Deal found 3/9![Avianca logo]()
$461
This Cheapflightsfares deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Tue 4/2812:25 pm
GYE
- SFO
1 stop13h 31m
JetBlue
Deal found 3/10![JetBlue logo]()
$447
This SmartFares deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Mon 4/273:51 pm
GYE
- SFO
1 stop19h 32m
JetBlue
Deal found 3/10![JetBlue logo]()
$477
This oojo deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Mon 4/276:50 pm
GYE
- SFO
2 stops31h 05m
Avianca
Deal found 3/10![Avianca logo]()
$513
This Justfly.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Mon 5/43:45 pm
GYE
- SFO
2 stops23h 05m
Avianca
Deal found 3/10![Avianca logo]()
$485
This JetBlue deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:45 pm
SFO
- GYE
1 stop18h 13m
JetBlue
Wed 4/223:51 pm
GYE
- SFO
1 stop19h 32m
JetBlue
Deal found 3/10![JetBlue logo]()
$452
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:15 pm
SFO
- GYE
2 stops16h 40m
Avianca
Wed 4/226:50 pm
GYE
- SFO
2 stops29h 45m
Avianca
Deal found 3/8![Avianca logo]()
$473
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/261:23 am
SFO
- GYE
1 stop10h 12m
Copa Airlines
Thu 4/308:28 am
GYE
- SFO
1 stop17h 12m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$419
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/261:23 am
SFO
- GYE
1 stop10h 12m
Copa Airlines
Thu 5/78:28 am
GYE
- SFO
1 stop17h 12m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:15 am
SFO
- GYE
1 stop12h 57m
American Airlines
Fri 5/16:05 am
GYE
- SFO
1 stop19h 54m
American Airlines
Deal found 3/9![American Airlines logo]()
$495
One-way flights from San Francisco to GuayaquilSearch for one-way flight options from San Francisco to Guayaquil. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from San Francisco to Guayaquil. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Mytrip deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:55 pm
SFO
- GYE
2 stops15h 40m
Avianca
Deal found 3/9![Avianca logo]()
$191
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:05 pm
SFO
- GYE
1 stop13h 21m
JetBlue
Deal found 3/12![JetBlue logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/261:23 am
SFO
- GYE
1 stop10h 12m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:20 pm
SFO
- GYE
3 stops47h 44m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$213
This deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:05 pm
SFO
- GYE
1 stop13h 21m
JetBlue
Deal found 3/8![JetBlue logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
SFO
- GYE
3 stops39h 04m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$234
This Copa Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:37 pm
SFO
- GYE
1 stop14h 58m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:16 pm
SFO
- GYE
2 stops21h 48m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$245
This BusinessClass deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:49 pm
SFO
- GYE
2 stops19h 55m
GOL
Deal found 3/11![GOL logo]()
$260
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:59 pm
SFO
- GYE
2 stops21h 37m
United Airlines
Deal found 3/8![United Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/221:54 am
SFO
- GYE
1 stop9h 40m
Copa Airlines
Deal found 3/11![Copa Airlines logo]()
$273
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:10 pm
SFO
- GYE
2 stops23h 36m
United Airlines
Deal found 3/11![United Airlines logo]()
$275
Find flight deals from San Francisco to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $419 (Copa Airlines) |
One-way from | $191 (Mytrip) |
Popular in | December |
Cheapest in | October |
Average price | $774 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Sun 4/26
1:23 am-1:35 pm
1 stop10h 12m
Guayaquil Jose Joaquin de Olmedo
Thu 4/30
8:28 am-11:40 pm
1 stop17h 12m
$419
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Tue 4/21
2:15 pm-8:55 am
2 stops16h 40m
Guayaquil Jose Joaquin de Olmedo
Wed 4/22
6:50 pm-12:50 pm
2 stops20h 00m
$473
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Sun 8/16
1:12 am-12:02 am
1 stop20h 50m
Guayaquil Jose Joaquin de Olmedo
Thu 8/20
11:48 am-11:40 pm
1 stop13h 52m
$478
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Sun 4/19
1:23 am-11:38 pm
1 stop20h 15m
Guayaquil Jose Joaquin de Olmedo
Mon 5/4
12:22 pm-11:40 pm
1 stop13h 18m
$514
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Tue 4/21
2:45 pm-10:58 am
1 stop18h 13m
Guayaquil Jose Joaquin de Olmedo
Wed 4/22
3:51 pm-9:23 am
1 stop19h 32m
$526
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Fri 5/8
10:28 pm-9:12 pm
2 stops20h 44m
Guayaquil Jose Joaquin de Olmedo
Sun 5/17
6:05 am-11:01 pm
1 stop18h 56m
$602
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Mon 4/6
12:45 am-5:31 pm
2 stops14h 46m
Guayaquil Jose Joaquin de Olmedo
Fri 4/17
8:28 am-11:59 pm
2 stops17h 31m
$609
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Mon 4/6
12:45 am-5:31 pm
2 stops14h 46m
Guayaquil Jose Joaquin de Olmedo
Sat 4/18
12:22 pm-7:16 am
2 stops20h 54m
$609
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Sat 4/11
11:55 pm-8:55 am
2 stops31h 00m
Guayaquil Jose Joaquin de Olmedo
Sat 4/18
9:10 am-12:50 pm
2 stops29h 40m
$638
San FranciscoGuayaquil
SFO - GYE
SFOGYE
San Francisco
Mon 8/17
11:59 pm-8:53 pm
2 stops18h 54m
Guayaquil Jose Joaquin de Olmedo
Thu 8/20
12:22 pm-12:16 am
2 stops13h 54m
$649
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Guayaquil in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on San Francisco-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from San Francisco with our price prediction graph.
SFO-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Guayaquil
How far ahead should I book a flight from San Francisco to Guayaquil?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Guayaquil. Price data was last updated on March 6, 2026.
Booking 60 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Francisco to Guayaquil?
Currently, June is the cheapest month in which you can book a flight from San Francisco to Guayaquil (average of $203). Flying from San Francisco to Guayaquil in March is currently the most expensive (average of $532). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated March 13, 2026.
See what other customers who have flown with Copa Airlines,United Airlines, andJetBlue from San Francisco to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Crew
8.1
Overall
7.5
Boarding
7.8
Food
6.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Crew
8.1
Overall
7.5
Boarding
7.8
Food
6.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Crew
8.1
Overall
7.5
Boarding
7.8
Food
6.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Crew
8.1
Overall
7.5
Boarding
7.8
Food
6.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Crew
8.1
Overall
7.5
Boarding
7.8
Food
6.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Entertainment
6.8
Crew
8.1
Overall
7.5
Boarding
7.8
Food
6.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 13, 2026.
San Francisco and Guayaquil flights
Browse other San Francisco and Guayaquil flight options. Last updated on March 13, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on March 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from San Francisco to Guayaquil
Discover the top 5 airlines that operate flights from San Francisco to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$577 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$352 | Average$566 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$419 | Average$681 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$486 | Average$648 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$570 | Average$774 | FlexibilityNo cancel fee | On-time71% |