HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$304+ Cheap flights from Denver (DEN) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — GYE
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$383
(United)

One-way from

$304
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$661
From Denver Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Denver Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Denver to Guayaquil

Cheapest flights from Denver to Guayaquil
Explore the most affordable flight options available from Denver to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1811:15 amDEN - GYE
2 stops20h 00mMultiple Airlines
Tue 12/22:35 pmGYE - DEN
2 stops35h 24mMultiple Airlines
Deal found 9/8$383
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:35 pmDEN - GYE
2 stops27h 02mUnited Airlines
Mon 9/298:32 amGYE - DEN
2 stops25h 19mUnited Airlines
Deal found 9/11$454
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1811:50 amDEN - GYE
2 stops24h 30mJetBlue
Tue 12/27:20 amGYE - DEN
1 stop16h 44mJetBlue
Deal found 9/8$487
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:00 amDEN - GYE
2 stops17h 37mUnited Airlines
Sat 10/118:30 amGYE - DEN
2 stops15h 43mUnited Airlines
Deal found 9/10$602
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1712:17 amDEN - GYE
1 stop20h 49mAmerican Airlines
Tue 12/26:00 amGYE - DEN
1 stop31h 29mAmerican Airlines
Deal found 9/8$728
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/128:34 pmDEN - GYE
2 stops26h 03mUnited Airlines
Fri 10/173:15 amGYE - DEN
2 stops31h 41mUnited Airlines
Deal found 9/10$751
This LATAM Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/612:50 amDEN - GYE
2 stops20h 33mLATAM Airlines
Wed 10/88:25 pmGYE - DEN
2 stops22h 24mLATAM Airlines
Deal found 9/10$755

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Denver to Guayaquil that are best for you.

Fly from

Denver

Fly to

Guayaquil

Route

Depart

Return

Price

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Tue 11/18

11:15 am-9:15 am

2 stops20h 00m

Guayaquil Jose Joaquin de Olmedo

Tue 12/2

2:35 pm-11:59 pm

2 stops35h 24m

$383

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Mon 1/19

5:01 am-11:42 pm

2 stops16h 41m

Guayaquil Jose Joaquin de Olmedo

Tue 2/3

8:34 am-11:41 pm

2 stops17h 07m

$497

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Mon 1/19

9:38 pm-1:34 pm

1 stop13h 56m

Guayaquil Jose Joaquin de Olmedo

Tue 2/3

8:34 am-5:16 pm

1 stop10h 42m

$504

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Tue 2/10

9:38 pm-1:34 pm

1 stop13h 56m

Guayaquil Jose Joaquin de Olmedo

Tue 2/17

8:34 am-5:16 pm

1 stop10h 42m

$504

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Sat 10/4

5:00 am-11:37 pm

2 stops17h 37m

Guayaquil Jose Joaquin de Olmedo

Sat 10/11

8:30 am-11:13 pm

2 stops15h 43m

$602

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Sun 12/14

6:00 am-6:30 pm

3 stops34h 30m

$304

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Fri 12/12

1:43 pm-2:30 pm

3 stops46h 47m

$358

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Sat 12/13

6:45 am-11:45 pm

2 stops15h 00m

$435

DenverGuayaquil

DEN - GYE

DENGYE

Denver Intl

Fri 12/12

12:04 pm-7:20 am

1 stop17h 16m

$479

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Denver to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Guayaquil

What is the cheapest month to book a flight from Denver to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Denver to Guayaquil (average of $440). Flying from Denver to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to GYE?

Find hourly flight availability from Denver to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Denver to Guayaquil in the afternoon. Doing so could potentially save you 28% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, United Airlines, and American Airlines from Denver to Guayaquil to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
8,937 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Denver to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Denver to Guayaquil?

    A quick flight from Denver to Guayaquil can take about 13h 56m. United Airlines provides one of the quickest options available for as low as $504. Airlines will cover a distance of 3297 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Denver to Guayaquil round-trip?

    Copa Airlines, at $392, was found to be the cheapest airline from Denver to Guayaquil.Alternate airlines to your destination round-trip include United Airlines and American Airlines. These flights start at 38% lower than the current average price 3 months from now.

  • Can I find deals for flights from Denver to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Denver to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Guayaquil.

  • Can I find deals for business class flights from Denver to Guayaquil?

    Yes. Cheapflights offers flight deals from Denver to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Denver to Guayaquil (average of $440). Flying from Denver to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Quito flights
Colorado Springs to Quito flights
Colorado Springs to Guayaquil flights
Denver to Manta flights

Top 3 airlines flying from Denver to Guayaquil

Discover the top 3 airlines that operate flights from Denver to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$392Average$571FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$416Average$556FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$492Average$852FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.