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Guatemala City

$256+ Cheap flights from Santiago (SCL) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GUA
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Santiago to Guatemala City

Cheapest flights from Santiago to Guatemala City
Explore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This Avianca deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/133:20 pm
SCL
-
GUA
1 stop12h 20m
Avianca
Wed 4/291:55 pm
GUA
-
SCL
1 stop12h 50m
Avianca
Deal found 3/20$518
This Copa Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:22 am
SCL
-
GUA
1 stop11h 26m
Copa Airlines
Tue 5/266:24 am
GUA
-
SCL
2 stops15h 02m
Copa Airlines
Deal found 3/20$521
This Copa Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:21 am
SCL
-
GUA
2 stops19h 19m
Copa Airlines
Sat 4/42:31 am
GUA
-
SCL
1 stop18h 55m
Copa Airlines
Deal found 3/19$529
This Avianca deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:40 am
SCL
-
GUA
2 stops14h 20m
Avianca
Thu 4/27:00 am
GUA
-
SCL
2 stops14h 20m
Avianca
Deal found 3/19$534
This Copa Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:30 am
SCL
-
GUA
1 stop11h 20m
Copa Airlines
Sat 4/254:37 pm
GUA
-
SCL
1 stop10h 33m
Copa Airlines
Deal found 3/19$536
This Copa Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:28 pm
SCL
-
GUA
2 stops12h 12m
Copa Airlines
Sat 4/42:31 am
GUA
-
SCL
1 stop18h 55m
Copa Airlines
Deal found 3/19$551
This Copa Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/223:32 am
SCL
-
GUA
2 stops21h 08m
Copa Airlines
Thu 4/304:26 am
GUA
-
SCL
1 stop12h 57m
Copa Airlines
Deal found 3/18$559
This Copa Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:22 am
SCL
-
GUA
1 stop11h 26m
Copa Airlines
Sat 8/227:09 am
GUA
-
SCL
1 stop10h 14m
Copa Airlines
Deal found 3/20$568

Find flight deals from Santiago to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$518
(Avianca)

One-way from

$256
(Avianca)

Popular in

January

Cheapest in

August

Average price

$524
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Guatemala City La Aurora flights.
Search Deals
From Santiago Arturo Merino Benitez to Guatemala City La Aurora
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Santiago to Guatemala City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 4/22

2:30 am-8:01 pm

1 stop19h 31m

Guatemala City La Aurora

Sun 4/26

6:24 am-3:00 am

2 stops18h 36m

$521

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Tue 4/14

11:25 am-9:41 pm

2 stops12h 16m

Guatemala City La Aurora

Thu 4/23

6:24 am-5:10 am

2 stops20h 46m

$521

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 4/8

4:17 am-9:41 pm

2 stops19h 24m

Guatemala City La Aurora

Tue 4/21

6:24 am-2:20 am

2 stops17h 56m

$521
Quickest round-trip

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Tue 4/21

4:49 am-9:41 pm

2 stops18h 52m

Guatemala City La Aurora

Thu 4/30

10:37 am-11:26 pm

1 stop10h 49m

$521

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Sun 5/3

2:22 am-7:59 pm

1 stop19h 37m

Guatemala City La Aurora

Mon 5/11

7:10 am-7:23 pm

1 stop10h 13m

$521

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 4/15

4:17 am-9:41 pm

2 stops19h 24m

Guatemala City La Aurora

Wed 4/22

6:24 am-7:23 pm

2 stops10h 59m

$521
Cheapest one-way

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Sun 4/12

6:40 am-5:00 pm

1 stop12h 20m

$256

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Fri 8/28

4:14 am-9:37 pm

2 stops19h 23m

$304

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Sat 5/9

4:09 am-11:08 pm

1 stop20h 59m

$304

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Sun 5/24

2:22 am-9:41 pm

2 stops21h 19m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 14 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santiago-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Guatemala City

How far ahead should I book a flight from Santiago to Guatemala City?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Guatemala City. Price data was last updated on March 13, 2026.

The best time to book flights from Santiago to Guatemala City is 10 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Guatemala City?

Currently, March is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $220). Flying from Santiago to Guatemala City in January is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated March 23, 2026.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Santiago to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,575 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,575 reviews
Copa Airlines
7.5
Good
1,575 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Avianca
6.5
Okay
2,505 reviews
Copa Airlines
7.5
Good
1,575 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Guatemala City?

    Airlines like Copa Airlines fly from Santiago to Guatemala City in about 21h 11m. The time it takes to get you to your destination can typically vary by up to . Santiago and Guatemala City are separated by a distance of 3559 mi.

  • What are the cheapest airlines flying from Santiago to Guatemala City round-trip?

    Cheapflights users have booked flights from Santiago to Guatemala City round-trip from $382. Another airline that can offer you cheap pricing is Copa Airlines. These flights start at 27% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santiago to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santiago to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Guatemala City.

  • Can I find deals for business class flights from Santiago to Guatemala City?

    Yes. Cheapflights offers flight deals from Santiago to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Guatemala City?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $220). Flying from Santiago to Guatemala City in January is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Guatemala City car rentals
Guatemala City La Aurora Airport car rentals

Top 2 airlines flying from Santiago to Guatemala City

Discover the top 2 airlines that operate flights from Santiago to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$382Average$522FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$454Average$524FlexibilityNo cancel feeOn-time70%

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