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Guatemala City

$255+ Cheap flights from Santiago (SCL) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GUA
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Guatemala City La Aurora are usually found in August or May, booked 10 days in advance, depart on a Friday or Tuesday and return on a Saturday

Cheap flight deals from Santiago to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$522
(Priceline)

One-way from

$255
(FlightHub)

Popular in

January

Cheapest in

August

Average price

$504
From Santiago Arturo Merino Benitez to Guatemala City La Aurora
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One-way flight from Santiago Arturo Merino Benitez to Guatemala City La Aurora
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Highest demand for flights based on searches. 11% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santiago to Guatemala City

Cheapest flights from Santiago to Guatemala City
Explore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Priceline deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/51:35 amSCL - GUA
1 stop14h 25mAvianca
Thu 11/139:30 amGUA - SCL
1 stop12h 00mAvianca
Deal found 9/11$522
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/303:35 amSCL - GUA
2 stops21h 03mCopa Airlines
Fri 11/147:15 amGUA - SCL
1 stop10h 06mCopa Airlines
Deal found 9/11$525
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/251:35 amSCL - GUA
1 stop14h 25mAvianca
Fri 10/319:40 pmGUA - SCL
2 stops14h 40mAvianca
Deal found 9/9$530
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/293:35 amSCL - GUA
2 stops21h 01mCopa Airlines
Fri 11/142:41 amGUA - SCL
1 stop18h 25mCopa Airlines
Deal found 9/11$533
This Priceline deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:25 amSCL - GUA
2 stops13h 25mAvianca
Tue 11/119:40 pmGUA - SCL
2 stops14h 40mAvianca
Deal found 9/9$538
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/91:29 amSCL - GUA
1 stop10h 27mCopa Airlines
Sat 11/154:21 amGUA - SCL
1 stop16h 45mCopa Airlines
Deal found 9/10$540
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/303:35 amSCL - GUA
2 stops21h 01mCopa Airlines
Sat 10/255:39 amGUA - SCL
2 stops15h 01mCopa Airlines
Deal found 9/9$548
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/284:25 pmSCL - GUA
1 stop12h 15mAvianca
Sun 1/189:30 amGUA - SCL
1 stop17h 00mAvianca
Deal found 9/9$550
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:12 amSCL - GUA
2 stops19h 26mMultiple Airlines
Tue 11/119:30 amGUA - SCL
1 stop12h 00mMultiple Airlines
Deal found 9/10$551
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/512:20 pmSCL - GUA
1 stop13h 27mCopa Airlines
Tue 11/115:39 amGUA - SCL
2 stops11h 42mCopa Airlines
Deal found 9/10$554
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:12 amSCL - GUA
2 stops19h 26mCopa Airlines
Fri 1/24:24 amGUA - SCL
1 stop16h 19mCopa Airlines
Deal found 9/11$555
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/123:35 amSCL - GUA
2 stops21h 01mCopa Airlines
Sun 10/195:39 amGUA - SCL
2 stops15h 25mCopa Airlines
Deal found 9/10$565

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Santiago to Guatemala City that are best for you.

Fly from

Santiago

Fly to

Guatemala City

Route

Depart

Return

Price

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Mon 10/6

4:47 am-7:44 pm

1 stop17h 57m

Guatemala City La Aurora

Mon 10/13

5:39 am-3:42 am

2 stops19h 03m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 10/15

3:35 am-9:36 pm

2 stops21h 01m

Guatemala City La Aurora

Sun 10/19

3:59 am-12:04 am

1 stop17h 05m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 10/29

1:13 am-9:18 am

1 stop11h 05m

Guatemala City La Aurora

Sat 11/15

5:39 am-3:43 am

2 stops19h 04m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Sun 10/26

12:20 pm-7:53 pm

1 stop10h 33m

Guatemala City La Aurora

Sun 11/2

5:39 am-3:43 am

2 stops19h 04m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Thu 11/6

12:20 pm-9:38 pm

2 stops12h 18m

Guatemala City La Aurora

Tue 11/11

5:39 am-8:21 pm

2 stops11h 42m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 11/5

12:20 pm-9:38 pm

2 stops12h 18m

Guatemala City La Aurora

Mon 11/10

4:21 am-3:43 am

1 stop20h 22m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 11/5

1:12 am-9:20 am

1 stop11h 08m

Guatemala City La Aurora

Thu 11/13

5:39 am-12:06 am

2 stops15h 27m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Tue 10/14

3:35 am-9:36 pm

2 stops21h 01m

Guatemala City La Aurora

Tue 10/21

3:59 am-3:42 am

1 stop20h 43m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Fri 10/17

12:55 am-3:14 pm

1 stop17h 19m

$255

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Tue 10/21

3:35 am-9:36 pm

2 stops21h 01m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 13 results
1
2

Best time to book a flight from Santiago to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Guatemala City

How far ahead should I book a flight from Santiago to Guatemala City?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Guatemala City. Price data was last updated on August 29, 2025.

The best time to book flights from Santiago to Guatemala City is 10 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Guatemala City?

Currently, January is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $291). Flying from Santiago to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to GUA?

Find hourly flight availability from Santiago to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Santiago to Guatemala City in the morning. Doing so could potentially save you 41% on the flight price compared to flying in the afternoon, which is usually more expensive.

How much does it cost to fly round-trip from Santiago to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Santiago to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

PEI - PTY

The attention to us was excellent. Help was provided with care.
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

PEI - PTY

The attention to us was excellent. Help was provided with care.
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

PEI - PTY

The attention to us was excellent. Help was provided with care.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Guatemala City?

    Airlines like Copa Airlines fly from Santiago to Guatemala City in about 17h 57m. The time it takes to get you to your destination can typically vary by up to . Santiago and Guatemala City are separated by a distance of 3559 mi.

  • What are the cheapest airlines flying from Santiago to Guatemala City round-trip?

    Cheapflights users have booked flights from Santiago to Guatemala City round-trip from $377. Another airline that can offer you cheap pricing is Avianca. These flights start at 27% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santiago to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santiago to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Guatemala City.

  • Can I find deals for business class flights from Santiago to Guatemala City?

    Yes. Cheapflights offers flight deals from Santiago to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Guatemala City?

    Currently, January is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $291). Flying from Santiago to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Guatemala City car rentals
Guatemala City La Aurora Airport car rentals

Top 2 airlines flying from Santiago to Guatemala City

Discover the top 2 airlines that operate flights from Santiago to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$377Average$575FlexibilityNo cancel feeOn-time70%
AviancaCheapest$394Average$491FlexibilityNo cancel feeOn-time71%

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