HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guatemala City

$257+ Cheap flights from Santiago (SCL) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GUA
nov. 28 — dic. 51
vie. 11/28
vie. 12/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santiago to Guatemala City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Guatemala City La Aurora are usually found in August or May, booked 83 days in advance, depart on a Friday or Tuesday and return on a Saturday

Find flight deals from Santiago to Guatemala City

Cheapest flights from Santiago to Guatemala City
Explore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 29, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/215:12 amSCL - GUA
1 stop20h 35mCopa Airlines
sáb. 11/224:21 amGUA - SCL
1 stop20h 22mCopa Airlines
Deal found 10/27$455
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/67:25 amSCL - GUA
2 stops13h 25mAvianca
jue. 11/131:55 pmGUA - SCL
1 stop12h 35mAvianca
Deal found 10/27$460
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/271:35 amSCL - GUA
1 stop19h 05mMultiple Airlines
mié. 12/31:55 pmGUA - SCL
2 stops29h 20mMultiple Airlines
Deal found 10/28$461
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/133:23 amSCL - GUA
2 stops21h 15mCopa Airlines
mar. 11/184:21 amGUA - SCL
1 stop16h 45mCopa Airlines
Deal found 10/28$463
This Priceline deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/297:25 amSCL - GUA
2 stops13h 25mAvianca
mar. 11/46:10 amGUA - SCL
2 stops15h 20mAvianca
Deal found 10/28$468
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/251:35 amSCL - GUA
1 stop14h 25mAvianca
jue. 12/49:30 amGUA - SCL
1 stop12h 00mAvianca
Deal found 10/28$470
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/251:35 amSCL - GUA
1 stop14h 25mMultiple Airlines
jue. 12/48:25 amGUA - SCL
2 stops27h 15mMultiple Airlines
Deal found 10/28$474
This Priceline deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/264:25 pmSCL - GUA
1 stop12h 15mAvianca
mié. 12/39:30 amGUA - SCL
1 stop17h 00mAvianca
Deal found 10/28$476
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/123:23 amSCL - GUA
2 stops21h 15mCopa Airlines
lun. 12/12:26 amGUA - SCL
1 stop18h 15mCopa Airlines
Deal found 10/28$490

Cheap flight deals from Santiago to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octubre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$455
(Copa Airlines)

One-way from

$257
(Priceline)

Popular in

January

Cheapest in

August

Average price

$524
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Guatemala City La Aurora flights.
Search Deals
From Santiago Arturo Merino Benitez to Guatemala City La Aurora
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
Use the filters below to find and compare flights from Santiago to Guatemala City that are best for you.

Fly from

Santiago

Fly to

Guatemala City

Route

Depart

Return

Price

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

jue. 11/13

3:23 am-11:50 am

1 stop11h 27m

Guatemala City La Aurora

mié. 11/19

5:39 am-3:43 am

2 stops19h 04m

$455

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

mié. 11/12

3:23 am-9:38 pm

2 stops21h 15m

Guatemala City La Aurora

mié. 11/19

4:21 am-12:06 am

1 stop16h 45m

$455

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

vie. 11/21

5:12 am-9:38 pm

2 stops19h 26m

Guatemala City La Aurora

dom. 11/23

5:39 am-12:06 am

2 stops15h 27m

$455

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

vie. 11/21

5:12 am-10:47 pm

1 stop20h 35m

Guatemala City La Aurora

mar. 11/25

7:15 am-3:43 am

1 stop17h 28m

$455

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

mar. 11/18

5:24 am-10:47 pm

1 stop20h 23m

Guatemala City La Aurora

mar. 11/25

5:39 am-3:24 am

2 stops18h 45m

$455

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

mié. 11/26

12:20 pm-9:38 pm

2 stops12h 18m

Guatemala City La Aurora

sáb. 11/29

5:39 am-11:41 pm

2 stops15h 02m

$463

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

mié. 11/26

12:20 pm-9:38 pm

2 stops12h 18m

Guatemala City La Aurora

mar. 12/2

4:21 am-11:41 pm

1 stop16h 20m

$490

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

mié. 11/12

3:23 am-9:38 pm

2 stops21h 15m

Guatemala City La Aurora

mar. 12/2

1:12 pm-3:43 am

1 stop11h 31m

$490

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

mié. 3/25

1:35 am-1:00 pm

1 stop14h 25m

$257

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

mié. 11/12

3:23 am-9:38 pm

2 stops21h 15m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 15 results
1
2

Compare providers for flights from Santiago to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Guatemala City in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-Guatemala City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santiago-Guatemala City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santiago-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Guatemala City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Guatemala City

How far ahead should I book a flight from Santiago to Guatemala City?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Guatemala City. Price data was last updated on October 24, 2025.

The best time to book flights from Santiago to Guatemala City is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Guatemala City?

Currently, March is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $238). Flying from Santiago to Guatemala City in February is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to GUA?

Find hourly flight availability from Santiago to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 29, 2025.

It’s typically best to fly out from Santiago to Guatemala City in the morning. Doing so could potentially save you 40% on the flight price compared to flying in the evening, which is usually more expensive.

How much does it cost to fly round-trip from Santiago to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated octubre 29, 2025.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Santiago to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,563 reviews

Boarding

7.8

Overall

7.6

Food

6.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,563 reviews
Copa Airlines
7.6
Good
1,563 reviews

Boarding

7.8

Overall

7.6

Food

6.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,467 reviews
Copa Airlines
7.6
Good
1,563 reviews

Boarding

7.8

Overall

7.6

Food

6.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santiago to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Guatemala City?

    Airlines like Copa Airlines fly from Santiago to Guatemala City in about 19h 26m. The time it takes to get you to your destination can typically vary by up to . Santiago and Guatemala City are separated by a distance of 3559 mi.

  • What are the cheapest airlines flying from Santiago to Guatemala City round-trip?

    Cheapflights users have booked flights from Santiago to Guatemala City round-trip from $382. Another airline that can offer you cheap pricing is Copa Airlines. These flights start at 28% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santiago to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santiago to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Guatemala City.

  • Can I find deals for business class flights from Santiago to Guatemala City?

    Yes. Cheapflights offers flight deals from Santiago to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Guatemala City?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $238). Flying from Santiago to Guatemala City in February is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Guatemala City car rentals
Guatemala City La Aurora Airport car rentals

Top 2 airlines flying from Santiago to Guatemala City

Discover the top 2 airlines that operate flights from Santiago to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$382Average$522FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$504Average$524FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.