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Guatemala City

$218+ Cheap flights from Santiago (SCL) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GUA
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Santiago to Guatemala City

Cheapest flights from Santiago to Guatemala City
Explore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:28 pm
SCL
-
GUA
1 stop10h 24m
Copa Airlines
Mon 3/236:24 am
GUA
-
SCL
2 stops15h 10m
Copa Airlines
Deal found 2/3$448
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/103:32 am
SCL
-
GUA
2 stops21h 08m
Copa Airlines
Wed 3/186:24 am
GUA
-
SCL
2 stops14h 25m
Copa Airlines
Deal found 2/3$456
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:17 am
SCL
-
GUA
1 stop13h 19m
Copa Airlines
Fri 3/206:24 am
GUA
-
SCL
2 stops10h 56m
Copa Airlines
Deal found 2/3$463
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:38 am
SCL
-
GUA
2 stops23h 03m
Copa Airlines
Thu 5/216:24 am
GUA
-
SCL
2 stops14h 19m
Copa Airlines
Deal found 2/3$471
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:40 am
SCL
-
GUA
1 stop32h 20m
Avianca
Sun 5/39:30 am
GUA
-
SCL
1 stop26h 45m
Avianca
Deal found 2/1$488
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/181:35 am
SCL
-
GUA
1 stop14h 25m
Avianca
Thu 3/261:55 pm
GUA
-
SCL
1 stop12h 35m
Avianca
Deal found 2/2$493
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/912:28 pm
SCL
-
GUA
1 stop13h 43m
Copa Airlines
Sun 3/156:24 am
GUA
-
SCL
2 stops14h 25m
Copa Airlines
Deal found 2/3$496
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:25 am
SCL
-
GUA
2 stops12h 16m
Copa Airlines
Wed 4/156:24 am
GUA
-
SCL
2 stops15h 02m
Copa Airlines
Deal found 2/3$511
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:17 am
SCL
-
GUA
2 stops19h 24m
Copa Airlines
Sat 4/42:31 am
GUA
-
SCL
1 stop14h 52m
Copa Airlines
Deal found 2/3$536
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:30 am
SCL
-
GUA
1 stop14h 30m
Avianca
Sat 5/26:20 am
GUA
-
SCL
1 stop15h 00m
Avianca
Deal found 2/1$541

Find flight deals from Santiago to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$448
(Copa Airlines)

One-way from

$218
(Avianca)

Popular in

January

Cheapest in

August

Average price

$566
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Guatemala City La Aurora flights.
Search Deals
From Santiago Arturo Merino Benitez to Guatemala City La Aurora
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Santiago to Guatemala City that are best for you.

Fly from

Santiago

Fly to

Guatemala City

Route

Depart

Return

Price

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Tue 3/31

1:46 am-8:49 am

1 stop10h 03m

Guatemala City La Aurora

Sun 4/5

4:26 am-10:43 pm

1 stop16h 17m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Thu 5/14

12:38 am-11:48 am

1 stop13h 10m

Guatemala City La Aurora

Fri 5/29

6:24 am-3:00 am

2 stops18h 36m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Tue 6/2

2:22 am-9:41 pm

2 stops21h 19m

Guatemala City La Aurora

Sun 6/7

6:24 am-3:00 am

2 stops18h 36m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Tue 3/31

1:46 am-9:36 am

1 stop10h 50m

Guatemala City La Aurora

Wed 4/15

6:24 am-11:26 pm

2 stops15h 02m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Mon 4/13

4:17 am-9:41 pm

2 stops19h 24m

Guatemala City La Aurora

Wed 4/29

6:24 am-10:43 pm

2 stops14h 19m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Fri 5/8

11:17 am-7:59 pm

1 stop10h 42m

Guatemala City La Aurora

Sun 5/17

4:24 am-10:43 pm

1 stop16h 19m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 3/18

5:44 am-9:40 pm

2 stops18h 56m

Guatemala City La Aurora

Sun 3/22

6:24 am-11:49 pm

2 stops14h 25m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Tue 3/31

1:09 am-9:36 am

1 stop11h 27m

Guatemala City La Aurora

Tue 4/7

6:24 am-11:26 pm

2 stops15h 02m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Thu 4/30

12:01 am-11:48 am

1 stop13h 47m

Guatemala City La Aurora

Thu 5/7

2:29 am-11:26 pm

1 stop18h 57m

$448

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Fri 3/6

1:35 am-1:00 pm

1 stop14h 25m

$218

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 17 results
1
2
  • Most accurate provider: When it comes to deals on Santiago-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Guatemala City

How far ahead should I book a flight from Santiago to Guatemala City?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Guatemala City. Price data was last updated on January 30, 2026.

The best time to book flights from Santiago to Guatemala City is 10 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Guatemala City?

Currently, March is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $237). Flying from Santiago to Guatemala City in January is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated February 3, 2026.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Santiago to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,558 reviews

Food

6.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.6
Good
1,558 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Avianca
6.5
Okay
2,498 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Santiago to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Guatemala City?

    Airlines like Copa Airlines fly from Santiago to Guatemala City in about 11h 27m. The time it takes to get you to your destination can typically vary by up to . Santiago and Guatemala City are separated by a distance of 3559 mi.

  • What are the cheapest airlines flying from Santiago to Guatemala City round-trip?

    Cheapflights users have booked flights from Santiago to Guatemala City round-trip from $328. Another airline that can offer you cheap pricing is Copa Airlines. These flights start at 37% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santiago to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santiago to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Guatemala City.

  • Can I find deals for business class flights from Santiago to Guatemala City?

    Yes. Cheapflights offers flight deals from Santiago to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Guatemala City?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $237). Flying from Santiago to Guatemala City in January is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Guatemala City car rentals
Guatemala City La Aurora Airport car rentals

Top 2 airlines flying from Santiago to Guatemala City

Discover the top 2 airlines that operate flights from Santiago to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$328Average$522FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$454Average$524FlexibilityNo cancel feeOn-time70%

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