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Guatemala City

$257+ Cheap flights from Santiago (SCL) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GUA
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Find cheap flights from Santiago to Guatemala City with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Guatemala City La Aurora are usually found in August or June, booked 10 days in advance, depart on a Friday or Tuesday and return on a Saturday

Cheap flight deals from Santiago to Guatemala City

Cheapest flights from Santiago to Guatemala City
Explore the most affordable flight options available from Santiago to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:08 amSCL - GUA
1 stop10h 48mCopa Airlines
Tue 1/610:34 amGUA - SCL
1 stop14h 40mCopa Airlines
Deal found 12/13$595
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/261:08 amSCL - GUA
1 stop11h 26mCopa Airlines
Sun 1/42:26 amGUA - SCL
1 stop19h 06mCopa Airlines
Deal found 12/15$625
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:29 amSCL - GUA
1 stop10h 27mCopa Airlines
Sat 12/274:21 amGUA - SCL
1 stop20h 22mCopa Airlines
Deal found 12/15$635
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1412:20 pmSCL - GUA
2 stops12h 18mCopa Airlines
Sun 12/216:24 amGUA - SCL
2 stops14h 17mCopa Airlines
Deal found 12/13$650
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/271:29 amSCL - GUA
1 stop11h 05mCopa Airlines
Sun 1/186:24 amGUA - SCL
2 stops15h 08mCopa Airlines
Deal found 12/15$680
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:44 amSCL - GUA
1 stop17h 11mCopa Airlines
Sun 1/410:34 amGUA - SCL
1 stop10h 58mCopa Airlines
Deal found 12/13$686
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:44 amSCL - GUA
2 stops18h 54mCopa Airlines
Sat 1/1010:34 amGUA - SCL
1 stop10h 09mCopa Airlines
Deal found 12/15$694
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:44 amSCL - GUA
1 stop17h 11mCopa Airlines
Fri 1/1610:34 amGUA - SCL
1 stop14h 40mCopa Airlines
Deal found 12/15$701
This Copa Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:12 amSCL - GUA
1 stop17h 43mCopa Airlines
Wed 12/314:24 amGUA - SCL
1 stop17h 08mCopa Airlines
Deal found 12/14$716

Find flight deals from Santiago to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$522
(Priceline)

One-way from

$257
(Priceline)

Popular in

January

Cheapest in

August

Average price

$559
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Guatemala City La Aurora flights.
Search Deals
From Santiago Arturo Merino Benitez to Guatemala City La Aurora
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Santiago to Guatemala City that are best for you.

Fly from

Santiago

Fly to

Guatemala City

Route

Depart

Return

Price

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Thu 5/7

2:22 am-11:48 am

1 stop11h 26m

Guatemala City La Aurora

Sun 5/17

6:24 am-10:43 pm

2 stops14h 19m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Mon 3/9

12:28 pm-9:40 pm

2 stops12h 12m

Guatemala City La Aurora

Fri 4/24

6:24 am-7:23 pm

2 stops10h 59m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Sat 3/14

5:21 am-9:40 pm

2 stops19h 19m

Guatemala City La Aurora

Wed 3/18

1:16 pm-6:00 am

1 stop13h 44m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Sat 2/28

5:20 am-9:40 pm

2 stops19h 20m

Guatemala City La Aurora

Fri 3/20

2:26 am-8:20 pm

1 stop14h 54m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 2/25

5:20 am-9:40 pm

2 stops19h 20m

Guatemala City La Aurora

Mon 3/23

4:24 am-3:58 am

1 stop20h 34m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 3/18

1:38 am-11:36 am

1 stop12h 58m

Guatemala City La Aurora

Sun 3/22

4:24 am-8:20 pm

1 stop12h 56m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Mon 3/9

3:32 am-9:40 pm

2 stops21h 08m

Guatemala City La Aurora

Thu 4/9

4:31 pm-5:03 am

1 stop10h 32m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Sat 2/28

5:20 am-9:40 pm

2 stops19h 20m

Guatemala City La Aurora

Sun 3/15

4:24 am-12:34 am

1 stop17h 10m

$525

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Wed 1/21

4:25 pm-1:00 pm

1 stop23h 35m

$257

SantiagoGuatemala City

SCL - GUA

SCLGUA

Santiago Arturo Merino Benitez

Thu 3/12

12:28 pm-11:11 pm

1 stop13h 43m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/12

Showing 1-10 of 16 results
1
2

Compare providers for flights from Santiago to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Guatemala City in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-Guatemala City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santiago-Guatemala City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santiago-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Guatemala City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Guatemala City

How far ahead should I book a flight from Santiago to Guatemala City?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Guatemala City. Price data was last updated on December 12, 2025.

The best time to book flights from Santiago to Guatemala City is 10 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Guatemala City?

Currently, March is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $245). Flying from Santiago to Guatemala City in February is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to GUA?

Find hourly flight availability from Santiago to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s typically best to fly out from Santiago to Guatemala City in the morning. Doing so could potentially save you 40% on the flight price compared to flying in the evening, which is usually more expensive.

How much does it cost to fly round-trip from Santiago to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated December 16, 2025.
Get a feel of what it's like to fly with Copa Airlines and Avianca from Santiago to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,556 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,556 reviews
Copa Airlines
7.6
Good
1,556 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,484 reviews
Copa Airlines
7.6
Good
1,556 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santiago to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Guatemala City?

    Airlines like Copa Airlines fly from Santiago to Guatemala City in about 11h 26m. The time it takes to get you to your destination can typically vary by up to . Santiago and Guatemala City are separated by a distance of 3559 mi.

  • What are the cheapest airlines flying from Santiago to Guatemala City round-trip?

    Cheapflights users have booked flights from Santiago to Guatemala City round-trip from $328. Another airline that can offer you cheap pricing is Copa Airlines. These flights start at 37% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santiago to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santiago to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Guatemala City.

  • Can I find deals for business class flights from Santiago to Guatemala City?

    Yes. Cheapflights offers flight deals from Santiago to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Guatemala City?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Guatemala City (average of $245). Flying from Santiago to Guatemala City in February is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Guatemala City car rentals
Guatemala City La Aurora Airport car rentals

Top 2 airlines flying from Santiago to Guatemala City

Discover the top 2 airlines that operate flights from Santiago to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$382Average$522FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$504Average$524FlexibilityNo cancel feeOn-time70%

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