$210+ Cheap flights from Santiago (SCL) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GYE
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo are usually found in August or November, booked 59 days in advance, depart on a Tuesday or Wednesday and return on a Friday
Cheap flight deals from Santiago to Guayaquil
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santiago to GuayaquilExplore the most affordable flight options available from Santiago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Santiago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:40 am -
1 stop11h 55m
Mon 10/510:05 am -
1 stop12h 15m
Deal found 9/9![Avianca logo]()
$452
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:40 am -
1 stop8h 55m
Thu 10/229:10 am -
1 stop13h 10m
Deal found 9/6![Avianca logo]()
$462
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:43 am -
1 stop11h 38m
Mon 9/286:28 pm -
1 stop9h 42m
Deal found 9/8![Copa Airlines logo]()
$474
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:40 am -
1 stop17h 50m
Sat 10/109:10 am -
1 stop13h 10m
Deal found 9/6![Avianca logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:22 pm -
1 stop24h 59m
Sat 10/175:38 pm -
Nonstop4h 51m
Deal found 9/6![Multiple Airlines logo]()
$497
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:14 am -
1 stop10h 07m
Tue 9/226:28 pm -
1 stop27h 54m
Deal found 9/6![Copa Airlines logo]()
$498
This CheapOair deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:20 pm -
1 stop18h 35m
Sun 10/45:38 pm -
Nonstop4h 51m
Deal found 9/4![Multiple Airlines logo]()
$506
This Gotogate deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:10 am -
1 stop11h 35m
Thu 10/225:38 pm -
Nonstop4h 51m
Deal found 9/6![LATAM Airlines logo]()
$508
This CheapOair deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:55 pm -
1 stop9h 45m
Mon 1/189:05 am -
1 stop10h 45m
Deal found 9/6![LATAM Airlines logo]()
$513
Best flights from Santiago to GuayaquilDiscover carefully curated flight deals from Santiago to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Santiago to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:40 am -
1 stop11h 55m
Mon 10/510:05 am -
1 stop12h 15m
Deal found 9/9![Avianca logo]()
$452
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/127:30 am -
1 stop9h 20m
Tue 1/265:28 pm -
Nonstop4h 53m
Deal found 9/7![LATAM Airlines logo]()
$457
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:43 am -
1 stop11h 38m
Mon 9/286:28 pm -
1 stop9h 42m
Deal found 9/8![Copa Airlines logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:47 am -
2 stops14h 21m
Sat 10/175:38 pm -
Nonstop4h 51m
Deal found 9/6![Multiple Airlines logo]()
$513
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:28 am -
1 stop9h 47m
Sun 11/156:38 pm -
1 stop27h 41m
Deal found 9/8![Copa Airlines logo]()
$474
This LATAM Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:55 pm -
1 stop9h 45m
Mon 1/189:05 am -
1 stop10h 45m
Deal found 9/8![LATAM Airlines logo]()
$498
This Justfly.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:20 pm -
2 stops18h 55m
Sun 10/46:50 pm -
1 stop27h 30m
Deal found 9/4![Avianca logo]()
$521
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:43 am -
1 stop11h 38m
Sun 9/2711:48 am -
1 stop14h 08m
Deal found 9/5![Copa Airlines logo]()
$474
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:45 am -
Nonstop5h 18m
Mon 10/59:00 am -
1 stop10h 55m
Deal found 9/9![LATAM Airlines logo]()
$498
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:56 am -
1 stop12h 03m
Mon 9/286:28 pm -
1 stop24h 04m
Deal found 9/4![Copa Airlines logo]()
$474
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:15 am -
1 stop10h 06m
Sun 10/46:30 pm -
1 stop27h 52m
Deal found 9/4![Copa Airlines logo]()
$474
Last-minute flights from Santiago to GuayaquilDiscover last-minute flight deals from Santiago to Guayaquil. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Guayaquil. Data last updated September 9, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:14 am -
1 stop10h 07m
Tue 9/226:28 pm -
1 stop27h 54m
Deal found 9/6![Copa Airlines logo]()
$498
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:43 am -
1 stop11h 38m
Mon 9/286:28 pm -
1 stop9h 42m
Deal found 9/8![Copa Airlines logo]()
$474
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:40 am -
1 stop17h 50m
Sat 10/109:10 am -
1 stop13h 10m
Deal found 9/6![Avianca logo]()
$479
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:40 am -
1 stop11h 55m
Mon 10/510:05 am -
1 stop12h 15m
Deal found 9/9![Avianca logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:22 pm -
1 stop24h 59m
Sat 10/175:38 pm -
Nonstop4h 51m
Deal found 9/6![Multiple Airlines logo]()
$497
This CheapOair deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:20 pm -
1 stop18h 35m
Sun 10/45:38 pm -
Nonstop4h 51m
Deal found 9/4![Multiple Airlines logo]()
$506
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:40 am -
1 stop8h 55m
Thu 10/229:10 am -
1 stop13h 10m
Deal found 9/6![Avianca logo]()
$462
This Gotogate deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:10 am -
1 stop11h 35m
Thu 10/225:38 pm -
Nonstop4h 51m
Deal found 9/6![LATAM Airlines logo]()
$508
One-way flights from Santiago to GuayaquilSearch for one-way flight options from Santiago to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Santiago to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:20 am -
1 stop8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![LATAM Airlines logo]()
$210
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:30 am -
1 stop9h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![LATAM Airlines logo]()
$230
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:22 pm -
1 stop24h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Copa Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:12 am -
2 stops14h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$234
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/58:40 am -
1 stop8h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![LATAM Airlines logo]()
$238
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:14 am -
1 stop10h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Copa Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:52 am -
1 stop21h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$261
Find flight deals from Santiago to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $444 (LATAM Airlines) |
One-way from | $210 (LATAM Airlines) |
Popular in | January |
Cheapest in | August |
Average price | $470 |
Good round-trip deal | $672 or less |
Good one-way deal | $242 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Santiago to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Mon 10/5
8:50 am-2:45 pm
1 stop7h 55m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$210
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Wed 11/18
5:55 pm-1:40 am
1 stop9h 45m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$210
Quickest round-trip
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Wed 11/11
1:45 am-5:03 am
Nonstop5h 18m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$225
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Wed 9/23
3:14 am-11:21 am
1 stop10h 07m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$232
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Thu 9/24
1:43 am-11:21 am
1 stop11h 38m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$232
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Wed 9/30
3:15 am-11:21 am
1 stop10h 06m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$232
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Wed 9/30
12:22 pm-11:21 am
1 stop24h 59m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$232
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Tue 1/5
8:40 am-2:50 pm
1 stop8h 10m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$238
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Tue 9/15
3:14 am-11:21 am
1 stop10h 07m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$244
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Thu 9/17
3:14 am-11:21 am
1 stop10h 07m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$244
Showing 1-10 of 21 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santiago-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Santiago with our price prediction graph.
SCL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Guayaquil
Prices
Delays
How far ahead should I book a flight from Santiago to Guayaquil?
The best time to book flights from Santiago to Guayaquil is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Santiago to Guayaquil?
Currently, August is the cheapest month in which you can book a flight from Santiago to Guayaquil (average of $423). Flying from Santiago to Guayaquil in January is currently the most expensive (average of $546). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SCL to GYE?
Find hourly flight availability from Santiago to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 9, 2026.
When flying from Santiago to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from Santiago to Guayaquil delayed?
About 9% of weekly flights between Santiago and Guayaquil have experienced delays in the past year, with the average delay time being 146 minutes.
What is the most punctual flight time for Santiago to Guayaquil flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Santiago to Guayaquil flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 9% of flights being delayed.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 9, 2026.
Read reviews from past customers who have flown LATAM Airlines from Santiago to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Comfort
7.3
Entertainment
7.0
Overall
7.4
Crew
8.0
Food
6.7
Reviews
1 / 20
8.0
ExcellentVictoria E,Mar 2026
SCL - JFK
Boarding
7.5
Comfort
7.3
Entertainment
7.0
Overall
7.4
Crew
8.0
Food
6.7
Reviews
1 / 20
8.0
ExcellentVictoria E,Mar 2026
SCL - JFK
Related info for your journey
Find useful and relevant information for your journey from Santiago to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Search flights from Santiago to Guayaquil by cabin class
Find flights from Santiago to Guayaquil, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Santiago and Guayaquil flights
Browse other Santiago and Guayaquil flight options. Last updated on September 9, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Santiago to Guayaquil
Discover the top airline that operate flights from Santiago to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$527 | FlexibilityNo cancel fee | On-time81% |