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Guayaquil

$219+ Cheap flights from Santiago (SCL) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GYE
Aug 24 — Aug 311
Mon 8/24
Mon 8/31
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo are usually found in October or November, booked 59 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Santiago to Guayaquil

Cheapest flights from Santiago to Guayaquil
Explore the most affordable flight options available from Santiago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.

This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:30 pm
SCL
-
GYE
1 stop13h 15m
LATAM Airlines
Tue 8/255:38 pm
GYE
-
SCL
Nonstop4h 51m
LATAM Airlines
Deal found 7/22$419
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/912:45 am
SCL
-
GYE
Nonstop5h 18m
LATAM Airlines
Tue 8/255:38 pm
GYE
-
SCL
Nonstop4h 51m
LATAM Airlines
Deal found 7/22$427
This CheapOair deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 am
SCL
-
GYE
1 stop10h 05m
LATAM Airlines
Sun 10/45:38 pm
GYE
-
SCL
Nonstop4h 51m
LATAM Airlines
Deal found 7/21$431
This FlightHub deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:40 am
SCL
-
GYE
1 stop17h 50m
Avianca
Sun 10/410:05 am
GYE
-
SCL
1 stop12h 15m
Avianca
Deal found 7/22$435
This Super.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:40 am
SCL
-
GYE
1 stop17h 50m
Avianca
Sat 8/2910:05 am
GYE
-
SCL
1 stop17h 40m
Avianca
Deal found 7/25$438
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:40 am
SCL
-
GYE
1 stop17h 50m
Multiple Airlines
Tue 8/255:38 pm
GYE
-
SCL
Nonstop4h 51m
Multiple Airlines
Deal found 7/22$443
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:40 am
SCL
-
GYE
1 stop11h 55m
Multiple Airlines
Thu 8/205:38 pm
GYE
-
SCL
Nonstop4h 51m
Multiple Airlines
Deal found 7/22$447
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:31 pm
SCL
-
GYE
2 stops17h 14m
LATAM Airlines
Fri 8/149:00 am
GYE
-
SCL
1 stop6h 45m
LATAM Airlines
Deal found 7/23$452
This FlightHub deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:40 am
SCL
-
GYE
1 stop8h 55m
Avianca
Tue 8/2510:05 am
GYE
-
SCL
1 stop17h 40m
Avianca
Deal found 7/25$453

Find flight deals from Santiago to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 25, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$419
(CheapOair)

One-way from

$219
(Super.com)

Popular in

January

Cheapest in

October

Average price

$499
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
Use the filters below to find and compare flights from Santiago to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Sun 8/9

12:45 am-5:03 am

Nonstop5h 18m

Guayaquil Jose Joaquin de Olmedo

Tue 8/25

5:38 pm-11:29 pm

Nonstop4h 51m

$427

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Wed 8/5

6:40 am-11:30 pm

1 stop17h 50m

Guayaquil Jose Joaquin de Olmedo

Sat 8/29

10:05 am-4:45 am

1 stop17h 40m

$438

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Tue 8/11

6:45 pm-1:45 am

1 stop8h 00m

Guayaquil Jose Joaquin de Olmedo

Tue 8/25

8:45 pm-4:50 am

1 stop7h 05m

$449

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Mon 8/10

10:31 pm-2:45 pm

2 stops17h 14m

Guayaquil Jose Joaquin de Olmedo

Fri 8/14

9:00 am-4:45 pm

1 stop6h 45m

$452

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Thu 10/1

2:30 pm-1:45 am

1 stop13h 15m

Guayaquil Jose Joaquin de Olmedo

Sun 10/4

9:05 am-4:25 am

1 stop17h 20m

$457

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Tue 8/4

12:30 am-8:55 am

1 stop9h 25m

Guayaquil Jose Joaquin de Olmedo

Sat 8/29

5:38 pm-11:29 pm

Nonstop4h 51m

$469

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Fri 8/14

6:40 am-5:35 pm

1 stop11h 55m

Guayaquil Jose Joaquin de Olmedo

Fri 8/21

8:45 pm-5:45 am

1 stop8h 00m

$473

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Tue 1/12

7:25 am-5:45 pm

1 stop12h 20m

Guayaquil Jose Joaquin de Olmedo

Tue 1/26

9:05 am-6:00 pm

1 stop6h 55m

$479

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Mon 8/10

6:40 am-11:30 pm

1 stop17h 50m

Guayaquil Jose Joaquin de Olmedo

Fri 8/14

10:05 am-4:45 am

1 stop17h 40m

$492
Cheapest one-way

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Sat 8/22

7:50 am-2:45 pm

1 stop7h 55m

$220

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/25

Showing 1-10 of 17 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santiago-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Guayaquil

How far ahead should I book a flight from Santiago to Guayaquil?

The best time to book flights from Santiago to Guayaquil is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Guayaquil?

Currently, October is the cheapest month in which you can book a flight from Santiago to Guayaquil (average of $421). Flying from Santiago to Guayaquil in January is currently the most expensive (average of $548). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to GYE?

Find hourly flight availability from Santiago to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 25, 2026.

When flying from Santiago to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Santiago to Guayaquil?

Airfare is typical for this route at the moment.

Santiago to Guayaquil flights typically cost between $414 and $530 in August.
The cheapest round-trip price found within the last 5 days was $419 on LATAM Airlines (Aug 11-Aug 25).

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated July 25, 2026.
Read reviews from past customers who have flown LATAM Airlines from Santiago to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,965 reviews

Boarding

7.5

Overall

7.4

Food

6.7

Comfort

7.3

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.
LATAM Airlines
7.4
Good
1,965 reviews
LATAM Airlines
7.4
Good
1,965 reviews

Boarding

7.5

Overall

7.4

Food

6.7

Comfort

7.3

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santiago to Guayaquil flight route?

    The Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Guayaquil?

    Airlines like Avianca and LATAM Airlines fly from Santiago to Guayaquil in about 8h. The time it takes to get you to your destination can typically vary by up to 9h 50m. The distance between Santiago and Guayaquil is about 2235 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Santiago to Guayaquil round-trip?

    Our cheapest airline available from Santiago to Guayaquil is LATAM Airlines. Our recent data shows that you can find tickets from as low as $320 on this airline. LATAM Airlines is currently priced 32% below the average price you’ll pay for this route.

  • Can I find deals for flights from Santiago to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Santiago to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Guayaquil.

  • Can I find deals for business class flights from Santiago to Guayaquil?

    Yes. Cheapflights offers flight deals from Santiago to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Guayaquil?

    Currently, October is the cheapest month in which you can book a flight from Santiago to Guayaquil (average of $421). Flying from Santiago to Guayaquil in January is currently the most expensive (average of $548). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santiago to Guayaquil

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Santiago to Quito flights

Top airline flying from Santiago to Guayaquil

Discover the top airline that operate flights from Santiago to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$320Average$527FlexibilityNo cancel feeOn-time81%

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