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Guayaquil

$232+ Cheap flights from Santiago (SCL) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GYE
Jun 20 — Jun 271
Sat 6/20
Sat 6/27
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo are usually found in August or October, booked 72 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Santiago to Guayaquil

Cheapest flights from Santiago to Guayaquil
Explore the most affordable flight options available from Santiago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.

This Super.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:40 am
SCL
-
GYE
1 stop11h 55m
Avianca
Tue 6/233:30 am
GYE
-
SCL
1 stop9h 45m
Avianca
Deal found 5/20$469
This Super.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:30 am
SCL
-
GYE
1 stop9h 25m
Avianca
Wed 6/310:05 am
GYE
-
SCL
1 stop12h 15m
Avianca
Deal found 5/20$470
This FlightHub deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:40 am
SCL
-
GYE
1 stop10h 05m
LATAM Airlines
Thu 6/48:45 pm
GYE
-
SCL
1 stop7h 05m
LATAM Airlines
Deal found 5/20$481
This FlightHub deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:30 am
SCL
-
GYE
1 stop15h 05m
Avianca
Wed 7/83:30 am
GYE
-
SCL
1 stop9h 45m
Avianca
Deal found 5/17$483
This FlightHub deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/212:30 am
SCL
-
GYE
1 stop15h 05m
Avianca
Sun 8/2310:05 am
GYE
-
SCL
1 stop12h 15m
Avianca
Deal found 5/18$484
This FlightHub deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:40 am
SCL
-
GYE
1 stop8h 55m
Avianca
Fri 7/1010:05 am
GYE
-
SCL
1 stop12h 15m
Avianca
Deal found 5/21$485
This FlightHub deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/303:20 pm
SCL
-
GYE
1 stop9h 10m
Avianca
Sat 6/63:30 am
GYE
-
SCL
1 stop9h 45m
Avianca
Deal found 5/19$486
This CheapOair deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:50 am
SCL
-
GYE
1 stop7h 55m
LATAM Airlines
Sun 8/239:05 am
GYE
-
SCL
1 stop17h 20m
LATAM Airlines
Deal found 5/16$487
This FlightHub deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:40 am
SCL
-
GYE
1 stop11h 55m
Avianca
Sun 7/123:30 am
GYE
-
SCL
1 stop18h 50m
Avianca
Deal found 5/20$489
This Avianca deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/243:20 pm
SCL
-
GYE
1 stop9h 10m
Avianca
Thu 8/2010:05 am
GYE
-
SCL
1 stop12h 15m
Avianca
Deal found 5/16$492

Find flight deals from Santiago to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$469
(Super.com)

One-way from

$232
(Super.com)

Popular in

January

Cheapest in

August

Average price

$477

Good one-way deal

$251 or less
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals
Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from Santiago to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Mon 8/3

7:50 am-2:45 pm

1 stop7h 55m

Guayaquil Jose Joaquin de Olmedo

Tue 8/18

9:05 am-3:25 am

1 stop17h 20m

$487
Quickest round-trip

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Sat 7/4

6:40 am-2:35 pm

1 stop8h 55m

Guayaquil Jose Joaquin de Olmedo

Mon 7/13

3:45 pm-4:45 am

1 stop12h 00m

$489

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Sun 8/2

12:30 am-2:35 pm

1 stop15h 05m

Guayaquil Jose Joaquin de Olmedo

Sun 8/23

9:05 am-11:20 pm

1 stop13h 15m

$491

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Sat 7/4

3:20 pm-11:30 pm

1 stop9h 10m

Guayaquil Jose Joaquin de Olmedo

Sat 7/11

10:05 am-4:45 am

1 stop17h 40m

$492

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Wed 8/12

12:06 am-8:53 pm

1 stop21h 47m

Guayaquil Jose Joaquin de Olmedo

Tue 8/18

11:48 am-5:14 am

1 stop16h 26m

$494

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Thu 7/23

2:14 am-8:53 pm

1 stop19h 39m

Guayaquil Jose Joaquin de Olmedo

Thu 8/20

12:22 pm-11:26 pm

1 stop10h 04m

$494

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Mon 10/5

1:44 am-8:52 pm

1 stop21h 08m

Guayaquil Jose Joaquin de Olmedo

Wed 10/21

12:18 pm-12:22 am

1 stop10h 04m

$494

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Tue 6/2

2:22 am-1:33 pm

1 stop12h 11m

Guayaquil Jose Joaquin de Olmedo

Tue 6/9

4:23 am-7:23 pm

1 stop14h 00m

$494

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Wed 9/23

1:43 am-11:21 am

1 stop11h 38m

Guayaquil Jose Joaquin de Olmedo

Tue 9/29

6:28 pm-11:39 pm

1 stop27h 11m

$494

SantiagoGuayaquil

SCL - GYE

SCLGYE

Santiago Arturo Merino Benitez

Wed 7/29

12:06 am-8:53 pm

1 stop21h 47m

Guayaquil Jose Joaquin de Olmedo

Sun 8/9

4:13 am-10:43 pm

1 stop17h 30m

$494

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/20

Showing 1-10 of 16 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santiago-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Guayaquil

How far ahead should I book a flight from Santiago to Guayaquil?

The best time to book flights from Santiago to Guayaquil is 71 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Guayaquil?

Currently, August is the cheapest month in which you can book a flight from Santiago to Guayaquil (average of $419). Flying from Santiago to Guayaquil in January is currently the most expensive (average of $550). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to GYE?

Find hourly flight availability from Santiago to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 21, 2026.

When flying from Santiago to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Santiago to Guayaquil?

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated May 21, 2026.
Read reviews from past customers who have flown LATAM Airlines from Santiago to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,921 reviews

Entertainment

7.0

Food

6.7

Crew

8.0

Comfort

7.3

Boarding

7.5

Overall

7.4

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.
LATAM Airlines
7.4
Good
1,921 reviews
LATAM Airlines
7.4
Good
1,921 reviews

Entertainment

7.0

Food

6.7

Crew

8.0

Comfort

7.3

Boarding

7.5

Overall

7.4

Reviews

1 / 20
8.0
Excellent

Victoria E,Mar 2026

SCL - JFK

I was charged $130 to check my baggage from Santiago Chile to New York. It was only one baggage checked and it wasn’t fully the standard size. And then to get hit with $130 was to me not favorable to the airlines. Because on most international travel, they allow one bag to be checked in. So in the future, I would have to think twice about booking Latam again other than that it’s a very good airline.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santiago to Guayaquil flight route?

    The Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Guayaquil?

    Airlines like LATAM Airlines and Avianca fly from Santiago to Guayaquil in about 7h 55m. The time it takes to get you to your destination can typically vary by up to 1h. The distance between Santiago and Guayaquil is about 2235 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Santiago to Guayaquil round-trip?

    Our cheapest airline available from Santiago to Guayaquil is LATAM Airlines. Our recent data shows that you can find tickets from as low as $320 on this airline. LATAM Airlines is currently priced 31% below the average price you’ll pay for this route.

  • What are the cheapest flights from Santiago to Guayaquil?

    Looking at all options, your cheapest flight can be booked for $246. While the most popular route (Santiago Arturo Merino Benitez - Guayaquil Jose Joaquin de Olmedo) can be booked for $453 on average, our data indicates $286 when flying from Santiago to Guayaquil.

  • Can I find deals for flights from Santiago to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Santiago to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Guayaquil.

  • Can I find deals for business class flights from Santiago to Guayaquil?

    Yes. Cheapflights offers flight deals from Santiago to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Guayaquil?

    Currently, August is the cheapest month in which you can book a flight from Santiago to Guayaquil (average of $419). Flying from Santiago to Guayaquil in January is currently the most expensive (average of $550). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to Quito flights

Top airline flying from Santiago to Guayaquil

Discover the top airline that operate flights from Santiago to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$320Average$527FlexibilityNo cancel feeOn-time81%

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