$232+ Cheap flights from Santiago (SCL) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — GYE
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Guayaquil Jose Joaquin de Olmedo are usually found in August or November, booked 79 days in advance, depart on a Tuesday or Wednesday and return on a Sunday
Cheap flight deals from Santiago to Guayaquil
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Best
Last-minute
One-way
Cheapest flights from Santiago to GuayaquilExplore the most affordable flight options available from Santiago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Santiago to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:15 pm -
1 stop9h 20m
Fri 11/1310:10 am -
1 stop12h 55m
Deal found 10/24![Avianca logo]()
$431
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
1 stop9h 40m
Tue 11/247:35 pm -
1 stop17h 35m
Deal found 10/23![Avianca logo]()
$459
This FlightHub deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:15 pm -
1 stop24h 55m
Fri 11/1310:10 am -
1 stop12h 55m
Deal found 10/24![Avianca logo]()
$474
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:10 am -
2 stops13h 20m
Mon 11/3010:10 am -
1 stop12h 55m
Deal found 10/21![Avianca logo]()
$479
This LATAM Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:40 am -
1 stop8h 10m
Wed 11/259:10 am -
1 stop10h 40m
Deal found 10/24![LATAM Airlines logo]()
$484
This LATAM Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:40 am -
1 stop8h 10m
Thu 11/268:00 pm -
2 stops15h 12m
Deal found 10/24![LATAM Airlines logo]()
$485
This LATAM Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:45 am -
Nonstop5h 18m
Sat 11/289:10 am -
1 stop6h 50m
Deal found 10/24![LATAM Airlines logo]()
$496
This LATAM Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:10 am -
1 stop12h 40m
Thu 11/268:00 pm -
2 stops15h 12m
Deal found 10/24![LATAM Airlines logo]()
$497
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:10 am -
1 stop18h 15m
Sat 11/283:30 am -
1 stop19h 35m
Deal found 10/21![Avianca logo]()
$500
This FlightHub deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:30 am -
1 stop12h 55m
Sun 11/293:30 am -
1 stop9h 40m
Deal found 10/21![Avianca logo]()
$501
Best flights from Santiago to GuayaquilDiscover carefully curated flight deals from Santiago to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Santiago to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
1 stop9h 40m
Tue 11/247:35 pm -
1 stop17h 35m
Deal found 10/23![Avianca logo]()
$459
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/128:25 pm -
2 stops13h 55m
Tue 1/269:05 am -
1 stop10h 45m
Deal found 10/20![LATAM Airlines logo]()
$530
This Copa Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/143:19 am -
1 stop12h 23m
Sun 1/316:34 pm -
1 stop27h 07m
Deal found 10/22![Copa Airlines logo]()
$586
This LATAM Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/187:05 pm -
2 stops17h 21m
Sun 1/318:00 pm -
1 stop7h 20m
Deal found 10/25![LATAM Airlines logo]()
$540
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/143:19 am -
1 stop12h 23m
Mon 1/46:34 pm -
1 stop27h 06m
Deal found 10/21![Copa Airlines logo]()
$615
This LATAM Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:45 am -
Nonstop5h 18m
Tue 11/245:28 pm -
Nonstop4h 53m
Deal found 10/23![LATAM Airlines logo]()
$588
Last-minute flights from Santiago to GuayaquilDiscover last-minute flight deals from Santiago to Guayaquil. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Guayaquil. Data last updated October 25, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:15 pm -
1 stop24h 55m
Fri 11/1310:10 am -
1 stop12h 55m
Deal found 10/24![Avianca logo]()
$474
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:15 pm -
1 stop9h 20m
Fri 11/1310:10 am -
1 stop12h 55m
Deal found 10/24![Avianca logo]()
$431
This LATAM Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:40 am -
1 stop8h 10m
Wed 11/259:10 am -
1 stop10h 40m
Deal found 10/24![LATAM Airlines logo]()
$484
This LATAM Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:40 am -
1 stop8h 10m
Thu 11/268:00 pm -
2 stops15h 12m
Deal found 10/24![LATAM Airlines logo]()
$485
This LATAM Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:45 am -
Nonstop5h 18m
Sat 11/289:10 am -
1 stop6h 50m
Deal found 10/24![LATAM Airlines logo]()
$496
This LATAM Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:10 am -
1 stop12h 40m
Thu 11/268:00 pm -
2 stops15h 12m
Deal found 10/24![LATAM Airlines logo]()
$497
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
1 stop9h 40m
Tue 11/247:35 pm -
1 stop17h 35m
Deal found 10/23![Avianca logo]()
$459
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:10 am -
2 stops13h 20m
Mon 11/3010:10 am -
1 stop12h 55m
Deal found 10/21![Avianca logo]()
$479
This FlightHub deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:30 am -
1 stop12h 55m
Sat 11/283:30 am -
1 stop9h 40m
Deal found 10/21![Avianca logo]()
$501
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:10 am -
1 stop18h 15m
Sat 11/283:30 am -
1 stop19h 35m
Deal found 10/21![Avianca logo]()
$500
One-way flights from Santiago to GuayaquilSearch for one-way flight options from Santiago to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Santiago to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:19 am -
1 stop9h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Copa Airlines logo]()
$232
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:19 am -
1 stop9h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Copa Airlines logo]()
$244
This SmartFares deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:45 am -
Nonstop5h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![LATAM Airlines logo]()
$247
This LATAM Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/39:59 pm -
2 stops18h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![LATAM Airlines logo]()
$251
This LATAM Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:13 am -
2 stops26h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![LATAM Airlines logo]()
$271
This Super.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:40 am -
1 stop9h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![LATAM Airlines logo]()
$272
This Super.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:15 pm -
2 stops30h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Avianca logo]()
$287
This LATAM Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/44:10 am -
2 stops15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![LATAM Airlines logo]()
$289
This Booking.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:05 pm -
1 stop8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![LATAM Airlines logo]()
$305
Find flight deals from Santiago to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $431 (Avianca) |
One-way from | $232 (Copa Airlines) |
Popular in | January |
Cheapest in | August |
Average price | $473 |
Good one-way deal | $252 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Santiago to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Mon 3/29
11:58 pm-10:14 am
1 stop12h 16m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$232
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Tue 11/10
3:19 am-11:18 am
1 stop9h 59m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$232
Quickest round-trip
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Thu 10/29
1:45 am-5:03 am
Nonstop5h 18m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$247
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Sun 1/3
5:41 pm-2:50 pm
2 stops23h 09m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$277
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Fri 10/30
4:15 pm-8:30 pm
2 stops30h 15m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$287
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Tue 1/5
7:05 pm-1:23 pm
2 stops20h 18m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$308
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Thu 12/17
5:07 am-5:36 pm
1 stop14h 29m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$316
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Thu 11/19
7:30 am-3:10 pm
1 stop9h 40m
Guayaquil Jose Joaquin de Olmedo
Tue 11/24
7:35 pm-3:10 pm
1 stop17h 35m
$459
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Tue 1/12
8:25 pm-8:20 am
2 stops13h 55m
Guayaquil Jose Joaquin de Olmedo
Tue 1/26
9:05 am-9:50 pm
1 stop10h 45m
$530
SantiagoGuayaquil
SCL Santiago Arturo Merino Benitez - GYE Guayaquil Jose Joaquin de Olmedo
SCLGYE
Santiago Arturo Merino Benitez
Mon 1/18
7:05 pm-10:26 am
2 stops17h 21m
Guayaquil Jose Joaquin de Olmedo
Sun 1/31
8:00 pm-5:20 am
1 stop7h 20m
$540
Showing 1-10 of 13 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santiago-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Santiago with our price prediction graph.
SCL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Guayaquil
Prices
Delays
How far ahead should I book a flight from Santiago to Guayaquil?
The best time to book flights from Santiago to Guayaquil is 78 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Santiago to Guayaquil?
Currently, August is the cheapest month in which you can book a flight from Santiago to Guayaquil (average of $423). Flying from Santiago to Guayaquil in January is currently the most expensive (average of $546). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SCL to GYE?
Find hourly flight availability from Santiago to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 25, 2026.
When flying from Santiago to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from Santiago to Guayaquil delayed?
About 11% of weekly flights between Santiago and Guayaquil have experienced delays in the past year, with the average delay time being 144 minutes.
What is the most punctual flight time for Santiago to Guayaquil flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Santiago to Guayaquil flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 11% of flights being delayed.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated October 25, 2026.
Read reviews from past customers who have flown LATAM Airlines from Santiago to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Entertainment
7.0
Crew
8.0
Food
6.8
Comfort
7.3
Overall
7.4
Reviews
1 / 20
8.0
ExcellentVictoria E,Mar 2026
SCL - JFK
Boarding
7.5
Entertainment
7.0
Crew
8.0
Food
6.8
Comfort
7.3
Overall
7.4
Reviews
1 / 20
8.0
ExcellentVictoria E,Mar 2026
SCL - JFK
Related info for your journey
Find useful and relevant information for your journey from Santiago to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Santiago and Guayaquil flights
Browse other Santiago and Guayaquil flight options. Last updated on October 25, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
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Top airline flying from Santiago to Guayaquil
Discover the top airline that operate flights from Santiago to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$532 | FlexibilityNo cancel fee | On-time81% |