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Guatemala City

$172+ Cheap flights from Knoxville (TYS) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
May 8 — May 151
Fri 5/8
Fri 5/15
1 adult, Economy
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Cheap flight deals from Knoxville to Guatemala City

Cheapest flights from Knoxville to Guatemala City
Explore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:15 pm
TYS
-
GUA
2 stops25h 20m
Multiple Airlines
Sun 5/1012:17 pm
GUA
-
TYS
1 stop6h 33m
Multiple Airlines
Deal found 4/7$407
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:15 pm
TYS
-
GUA
2 stops25h 20m
Multiple Airlines
Tue 5/512:17 pm
GUA
-
TYS
1 stop20h 19m
Multiple Airlines
Deal found 4/6$438
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:56 am
TYS
-
GUA
1 stop25h 09m
Multiple Airlines
Tue 5/512:17 pm
GUA
-
TYS
1 stop20h 19m
Multiple Airlines
Deal found 4/6$447
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:15 pm
TYS
-
GUA
1 stop23h 41m
Multiple Airlines
Wed 5/611:18 am
GUA
-
TYS
2 stops31h 32m
Multiple Airlines
Deal found 4/6$484
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:56 am
TYS
-
GUA
1 stop25h 09m
Multiple Airlines
Wed 5/611:18 am
GUA
-
TYS
2 stops31h 32m
Multiple Airlines
Deal found 4/6$501
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:49 pm
TYS
-
GUA
2 stops12h 21m
Multiple Airlines
Tue 6/1612:17 pm
GUA
-
TYS
1 stop27h 41m
Multiple Airlines
Deal found 4/7$506
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:25 pm
TYS
-
GUA
1 stop16h 58m
Multiple Airlines
Mon 9/75:25 am
GUA
-
TYS
2 stops11h 26m
Multiple Airlines
Deal found 4/8$541
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:38 pm
TYS
-
GUA
2 stops39h 45m
Multiple Airlines
Thu 5/288:00 pm
GUA
-
TYS
1 stop18h 40m
Multiple Airlines
Deal found 4/6$609
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:19 pm
TYS
-
GUA
2 stops39h 04m
Multiple Airlines
Fri 7/3111:16 am
GUA
-
TYS
1 stop10h 17m
Multiple Airlines
Deal found 4/5$616
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:13 am
TYS
-
GUA
1 stop5h 42m
American Airlines
Mon 11/27:00 am
GUA
-
TYS
1 stop8h 37m
American Airlines
Deal found 4/6$625

Find flight deals from Knoxville to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$407
(Kiwi.com)

One-way from

$172
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$344
Provider with most accurate pricing for Knoxville McGhee Tyson-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Guatemala City La Aurora flights.
Search Deals
From Knoxville McGhee Tyson to Guatemala City La Aurora
Search Deals
One-way flight from Knoxville McGhee Tyson to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($189 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 5/19

6:30 am-2:02 pm

1 stop9h 32m

Guatemala City La Aurora

Mon 5/25

12:35 am-5:45 pm

2 stops15h 10m

$643
Quickest round-trip

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 9/18

5:40 am-11:00 am

1 stop7h 20m

Guatemala City La Aurora

Sat 9/19

1:15 pm-11:31 pm

1 stop8h 16m

$653

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 5/23

5:45 am-5:50 am

1 stop26h 05m

Guatemala City La Aurora

Wed 6/3

5:25 am-8:34 pm

2 stops13h 09m

$699

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 5/23

11:43 am-11:31 pm

1 stop13h 48m

Guatemala City La Aurora

Wed 6/3

10:08 am-11:59 pm

1 stop11h 51m

$717

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 9/4

7:30 am-1:24 pm

1 stop7h 54m

Guatemala City La Aurora

Mon 9/7

12:04 pm-11:18 pm

1 stop9h 14m

$764

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 5/1

5:40 am-11:46 am

1 stop8h 06m

Guatemala City La Aurora

Wed 5/6

1:14 pm-11:54 pm

1 stop8h 40m

$771
Cheapest one-way
Quickest one-way

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 4/20

1:15 pm-11:10 am

2 stops23h 55m

$172

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/4

Sorted by cheapest first

Compare providers for flights from Knoxville to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Guatemala City in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guatemala City

How much does it cost to fly round-trip from Knoxville to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated April 8, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Knoxville to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,388 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,388 reviews
Delta
7.9
Good
8,388 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,548 reviews
Delta
7.9
Good
8,388 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Guatemala City?

    American Airlines and Avianca can get you from Knoxville to Guatemala City in just under 9h 32m. Your travel time can differ by up to 16h 33m. The distance from Knoxville to Guatemala City is about 1520 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Guatemala City round-trip?

    Currently priced at $463, American Airlines will fly you from Knoxville to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $576. American Airlines is 21% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guatemala City.

  • Can I find deals for business class flights from Knoxville to Guatemala City?

    Yes. Cheapflights offers flight deals from Knoxville to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Guatemala City flights
Memphis to Guatemala City flights

Top 2 airlines flying from Knoxville to Guatemala City

Discover the top 2 airlines that operate flights from Knoxville to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$598FlexibilityNo cancel feeOn-time71%
DeltaCheapest$576Average$752FlexibilityNo cancel feeOn-timeN/A

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