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Guatemala City

$306+ Cheap flights from Knoxville (TYS) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Jun 6 — Jun 131
Sat 6/6
Sat 6/13
1 adult, Economy
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Cheap flight deals from Knoxville to Guatemala City

Cheapest flights from Knoxville to Guatemala City
Explore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.

This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am
TYS
-
GUA
1 stop5h 37m
American Airlines
Tue 11/246:36 am
GUA
-
TYS
1 stop8h 01m
American Airlines
Deal found 5/3$595
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:27 am
TYS
-
GUA
1 stop20h 23m
Multiple Airlines
Sun 5/178:15 pm
GUA
-
TYS
2 stops19h 15m
Multiple Airlines
Deal found 5/3$603
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am
TYS
-
GUA
1 stop9h 24m
American Airlines
Tue 10/2012:04 pm
GUA
-
TYS
1 stop7h 50m
American Airlines
Deal found 5/6$623
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:40 am
TYS
-
GUA
1 stop7h 20m
American Airlines
Sat 9/1912:04 pm
GUA
-
TYS
1 stop9h 14m
American Airlines
Deal found 5/5$653
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:59 pm
TYS
-
GUA
2 stops15h 09m
American Airlines
Wed 6/32:25 pm
GUA
-
TYS
1 stop7h 34m
American Airlines
Deal found 5/4$684
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:12 am
TYS
-
GUA
2 stops14h 15m
American Airlines
Fri 6/512:23 pm
GUA
-
TYS
1 stop9h 32m
American Airlines
Deal found 5/2$696
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:12 am
TYS
-
GUA
2 stops14h 15m
American Airlines
Fri 8/282:25 pm
GUA
-
TYS
1 stop7h 34m
American Airlines
Deal found 5/2$698
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:33 pm
TYS
-
GUA
1 stop7h 57m
American Airlines
Mon 6/2210:08 am
GUA
-
TYS
1 stop11h 51m
American Airlines
Deal found 5/6$727

Find flight deals from Knoxville to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$623
(American Airlines)

One-way from

$306
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$153
Provider with most accurate pricing for Knoxville McGhee Tyson-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Guatemala City La Aurora flights.
Search Deals
From Knoxville McGhee Tyson to Guatemala City La Aurora
Search Deals
One-way flight from Knoxville McGhee Tyson to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($189 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 9/18

5:40 am-11:00 am

1 stop7h 20m

Guatemala City La Aurora

Sat 9/19

12:04 pm-11:18 pm

1 stop9h 14m

$653

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 8/18

5:45 am-4:37 pm

2 stops12h 52m

Guatemala City La Aurora

Fri 8/21

1:30 am-11:17 am

1 stop7h 47m

$653

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 8/24

7:15 am-6:49 pm

1 stop13h 34m

Guatemala City La Aurora

Wed 8/26

1:30 am-11:57 pm

2 stops20h 27m

$747

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 5/29

7:12 am-7:27 pm

2 stops14h 15m

Guatemala City La Aurora

Fri 6/5

6:01 am-9:31 pm

2 stops13h 30m

$749

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 6/18

7:34 pm-9:08 am

1 stop15h 34m

Guatemala City La Aurora

Thu 6/25

12:23 pm-11:55 pm

1 stop9h 32m

$756

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 5/23

5:40 am-11:31 am

1 stop7h 51m

Guatemala City La Aurora

Thu 6/4

1:01 pm-11:56 pm

1 stop8h 55m

$773

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 5/23

5:40 am-11:31 am

1 stop7h 51m

Guatemala City La Aurora

Wed 6/3

1:01 pm-12:01 am

1 stop9h 00m

$773

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 5/23

5:33 pm-11:31 pm

1 stop7h 58m

Guatemala City La Aurora

Wed 6/3

10:08 am-11:59 pm

1 stop11h 51m

$779
Cheapest one-way

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 6/30

5:02 pm-11:55 am

3 stops44h 53m

$306

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sun 7/5

9:11 pm-11:55 am

3 stops40h 44m

$346

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/5

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Guatemala City in May.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guatemala City

How much does it cost to fly round-trip from Knoxville to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated May 7, 2026.
Get a feel of what it's like to fly with American Airlines from Knoxville to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,669 reviews

Overall

7.1

Crew

7.9

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,669 reviews
American Airlines
7.1
Good
11,669 reviews

Overall

7.1

Crew

7.9

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Guatemala City?

    American Airlines and United Airlines can get you from Knoxville to Guatemala City in just under 7h 20m. Your travel time can differ by up to 5h 32m. The distance from Knoxville to Guatemala City is about 1520 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Knoxville to Guatemala City round-trip?

    Currently priced at $463, American Airlines will fly you from Knoxville to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is 21% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guatemala City.

  • Can I find deals for business class flights from Knoxville to Guatemala City?

    Yes. Cheapflights offers flight deals from Knoxville to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Guatemala City flights
Memphis to Guatemala City flights

Top airline flying from Knoxville to Guatemala City

Discover the top airline that operate flights from Knoxville to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$598FlexibilityNo cancel feeOn-time71%

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