$471+ Cheap flights from Knoxville (TYS) to Guatemala City (GUA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Nov 29 — Dec 61
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Guatemala City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to Guatemala CityExplore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:55 pm -
1 stop8h 30m
Wed 11/1111:57 pm -
1 stop9h 47m
Deal found 10/28![United Airlines logo]()
$787
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:49 pm -
1 stop20h 02m
Mon 1/42:27 pm -
1 stop27h 49m
Deal found 10/28![Multiple Airlines logo]()
$813
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:17 pm -
1 stop14h 53m
Fri 1/12:27 pm -
2 stops26h 00m
Deal found 10/28![Multiple Airlines logo]()
$817
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:48 am -
2 stops14h 37m
Wed 11/116:00 am -
2 stops12h 00m
Deal found 10/28![American Airlines logo]()
$835
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:45 am -
2 stops18h 20m
Sat 12/58:00 pm -
1 stop17h 53m
Deal found 10/28![Multiple Airlines logo]()
$855
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
2 stops14h 20m
Sat 12/510:00 am -
2 stops12h 59m
Deal found 10/28![Avianca logo]()
$856
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop15h 23m
Fri 11/63:10 pm -
1 stop7h 49m
Deal found 10/27![American Airlines logo]()
$865
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Tue 11/177:35 pm -
1 stop11h 15m
Sat 11/218:00 pm -
1 stop14h 30m
Deal found 10/27![Avianca logo]()
$875
Best flights from Knoxville to Guatemala CityDiscover carefully curated flight deals from Knoxville to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Knoxville to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/610:45 am -
2 stops9h 54m
Fri 2/122:10 am -
1 stop8h 01m
Deal found 10/27![United Airlines logo]()
$715
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:45 am -
1 stop25h 05m
Sat 12/58:00 pm -
1 stop26h 59m
Deal found 10/26![Avianca logo]()
$901
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:30 am -
2 stops15h 55m
Tue 1/192:10 am -
2 stops11h 37m
Deal found 10/26![United Airlines logo]()
$840
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2410:16 am -
1 stop12h 14m
Wed 4/2812:27 pm -
1 stop8h 52m
Deal found 10/27![United Airlines logo]()
$883
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/162:04 pm -
1 stop8h 21m
Mon 1/1811:57 pm -
2 stops13h 50m
Deal found 10/26![United Airlines logo]()
$896
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:40 pm -
2 stops28h 45m
Sat 12/51:28 pm -
3 stops21h 11m
Deal found 10/29![United Airlines logo]()
$960
Last-minute flights from Knoxville to Guatemala CityDiscover last-minute flight deals from Knoxville to Guatemala City. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Guatemala City. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop15h 23m
Fri 11/63:10 pm -
1 stop7h 49m
Deal found 10/27![American Airlines logo]()
$865
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:55 pm -
1 stop8h 30m
Wed 11/1111:57 pm -
1 stop9h 47m
Deal found 10/28![United Airlines logo]()
$787
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:48 am -
2 stops14h 37m
Wed 11/116:00 am -
2 stops12h 00m
Deal found 10/28![American Airlines logo]()
$835
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:45 am -
2 stops18h 20m
Sat 12/58:00 pm -
1 stop17h 53m
Deal found 10/28![Multiple Airlines logo]()
$855
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
2 stops14h 20m
Sat 12/510:00 am -
2 stops12h 59m
Deal found 10/28![Avianca logo]()
$856
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:35 pm -
1 stop11h 15m
Sat 11/218:00 pm -
1 stop14h 30m
Deal found 10/27![Avianca logo]()
$875
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:45 am -
2 stops14h 20m
Sat 11/218:15 pm -
2 stops14h 15m
Deal found 10/27![Multiple Airlines logo]()
$887
One-way flights from Knoxville to Guatemala CitySearch for one-way flight options from Knoxville to Guatemala City. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Knoxville to Guatemala City. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:30 am -
3 stops32h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:47 pm -
1 stop18h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$704
This Gurufare deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:08 am -
1 stop11h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![GOL logo]()
$711
Find flight deals from Knoxville to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $715 (United Airlines) |
One-way from | $471 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Thu 12/17
6:30 am-1:42 pm
3 stops32h 12m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$471
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Thu 12/17
6:47 pm-12:08 pm
1 stop18h 21m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$704
Quickest round-trip
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Thu 12/17
5:08 am-3:11 pm
1 stop11h 03m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$711
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 2/6
10:45 am-7:39 pm
2 stops9h 54m
Guatemala City La Aurora
Fri 2/12
2:10 am-11:11 am
1 stop8h 01m
$715
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Thu 1/14
6:30 am-9:25 pm
2 stops15h 55m
Guatemala City La Aurora
Tue 1/19
2:10 am-2:47 pm
2 stops11h 37m
$840
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 4/24
10:16 am-8:30 pm
1 stop12h 14m
Guatemala City La Aurora
Wed 4/28
12:27 pm-11:19 pm
1 stop8h 52m
$883
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 1/16
2:04 pm-9:25 pm
1 stop8h 21m
Guatemala City La Aurora
Mon 1/18
11:57 pm-2:47 pm
2 stops13h 50m
$896
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 11/14
5:45 am-5:50 am
1 stop25h 05m
Guatemala City La Aurora
Sat 12/5
8:00 pm-11:59 pm
1 stop26h 59m
$901
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 11/14
5:40 pm-9:25 pm
2 stops28h 45m
Guatemala City La Aurora
Sat 12/5
1:28 pm-11:39 am
3 stops21h 11m
$960
Sorted by cheapest first
Compare providers for flights from Knoxville to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Guatemala City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Knoxville-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Knoxville with our price prediction graph.
TYS-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated October 30, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Knoxville to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Entertainment
7.1
Crew
8.1
Overall
7.3
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Entertainment
7.1
Crew
8.1
Overall
7.3
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Entertainment
7.1
Crew
8.1
Overall
7.3
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Guatemala City flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Guatemala City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Guatemala City by cabin class
Find flights from Knoxville to Guatemala City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Knoxville and Guatemala City flights
Browse other Knoxville and Guatemala City flight options. Last updated on October 30, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Guatemala City
Discover the top 2 airlines that operate flights from Knoxville to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$509 | Average$812 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$545 | Average$762 | FlexibilityNo cancel fee | On-time69% |