$393+ Cheap flights from Knoxville (TYS) to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Sep 29 — Oct 61
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Guatemala City
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Best
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Cheapest flights from Knoxville to Guatemala CityExplore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 30, 2026.
Explore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 30, 2026.
This Avianca deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:25 pm -
1 stop12h 25m
Sat 10/318:00 pm -
1 stop14h 30m
Deal found 8/27![Avianca logo]()
$656
This Avianca deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
2 stops12h 25m
Sat 12/55:25 am -
2 stops12h 03m
Deal found 8/27![Multiple Airlines logo]()
$659
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:45 am -
2 stops10h 50m
Tue 11/1011:57 pm -
1 stop9h 47m
Deal found 8/26![United Airlines logo]()
$663
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:11 pm -
2 stops18h 53m
Tue 11/104:12 pm -
2 stops16h 33m
Deal found 8/26![American Airlines logo]()
$667
This Avianca deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:25 pm -
1 stop12h 25m
Mon 10/198:00 pm -
1 stop12h 37m
Deal found 8/27![Avianca logo]()
$679
This Avianca deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:25 pm -
1 stop12h 25m
Mon 10/198:15 pm -
2 stops12h 22m
Deal found 8/30![Multiple Airlines logo]()
$689
This Mytrip deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
1 stop21h 05m
Sat 12/58:00 pm -
1 stop26h 39m
Deal found 8/27![Avianca logo]()
$704
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop9h 20m
Fri 10/22:21 pm -
1 stop6h 46m
Deal found 8/28![American Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:15 am -
1 stop6h 09m
Sun 11/151:05 am -
1 stop9h 25m
Deal found 8/26![United Airlines logo]()
$712
Best flights from Knoxville to Guatemala CityDiscover carefully curated flight deals from Knoxville to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 30, 2026.
Discover carefully curated flight deals from Knoxville to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 30, 2026.
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:45 am -
2 stops10h 50m
Tue 11/1011:57 pm -
1 stop9h 47m
Deal found 8/26![United Airlines logo]()
$663
This Avianca deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
2 stops12h 25m
Sat 12/55:25 am -
2 stops12h 03m
Deal found 8/27![Multiple Airlines logo]()
$668
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:45 am -
2 stops14h 20m
Sun 2/146:50 am -
2 stops13h 48m
Deal found 8/27![American Airlines logo]()
$684
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:40 am -
1 stop7h 52m
Thu 11/122:11 pm -
1 stop8h 48m
Deal found 8/30![Delta logo]()
$864
This Avianca deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:35 pm -
2 stops11h 35m
Sat 10/318:00 pm -
1 stop14h 30m
Deal found 8/28![Multiple Airlines logo]()
$712
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:15 am -
1 stop6h 09m
Sun 11/151:05 am -
1 stop9h 25m
Deal found 8/26![United Airlines logo]()
$712
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:11 am -
2 stops14h 12m
Sat 10/312:05 pm -
2 stops19h 59m
Deal found 8/28![American Airlines logo]()
$721
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:06 pm -
2 stops18h 58m
Sun 10/186:01 am -
2 stops15h 54m
Deal found 8/27![American Airlines logo]()
$748
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:43 am -
2 stops26h 43m
Fri 11/611:57 pm -
2 stops19h 57m
Deal found 8/30![United Airlines logo]()
$882
Last-minute flights from Knoxville to Guatemala CityDiscover last-minute flight deals from Knoxville to Guatemala City. Data last updated August 30, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Guatemala City. Data last updated August 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:00 am -
2 stops11h 37m
Wed 9/212:27 pm -
1 stop7h 18m
Deal found 8/27![United Airlines logo]()
$915
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:25 pm -
2 stops17h 42m
Wed 9/22:23 pm -
2 stops19h 21m
Deal found 8/27![American Airlines logo]()
$919
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:05 am -
1 stop6h 41m
Sat 9/192:21 pm -
1 stop6h 46m
Deal found 8/27![American Airlines logo]()
$864
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop9h 20m
Fri 10/22:21 pm -
1 stop6h 46m
Deal found 8/28![American Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:15 am -
1 stop6h 09m
Sun 11/151:05 am -
1 stop9h 25m
Deal found 8/26![United Airlines logo]()
$712
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:30 am -
1 stop7h 50m
Mon 11/1611:25 am -
2 stops10h 23m
Deal found 8/26![American Airlines logo]()
$739
One-way flights from Knoxville to Guatemala CitySearch for one-way flight options from Knoxville to Guatemala City. Find affordable one-way fares based on user searches. Data last updated August 30, 2026.
Search for one-way flight options from Knoxville to Guatemala City. Find affordable one-way fares based on user searches. Data last updated August 30, 2026.
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:16 pm -
1 stop16h 07m
Deal found 8/27![American Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:40 pm -
2 stops19h 46m
Deal found 8/28![United Airlines logo]()
$459
Find flight deals from Knoxville to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $655 (American Airlines) |
One-way from | $393 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 30, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Tue 10/27
5:45 am-2:35 pm
2 stops10h 50m
Guatemala City La Aurora
Tue 11/10
11:57 pm-10:44 am
1 stop9h 47m
$663
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 11/14
7:00 am-6:25 pm
2 stops12h 25m
Guatemala City La Aurora
Sat 12/5
5:25 am-6:28 pm
2 stops12h 03m
$668
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 2/6
7:45 am-9:05 pm
2 stops14h 20m
Guatemala City La Aurora
Sun 2/14
6:50 am-9:38 pm
2 stops13h 48m
$684
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 10/17
1:35 pm-11:10 pm
2 stops11h 35m
Guatemala City La Aurora
Sat 10/31
8:00 pm-12:30 pm
1 stop14h 30m
$712
Quickest round-trip
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Fri 9/25
7:15 am-11:24 am
1 stop6h 09m
Guatemala City La Aurora
Sun 11/15
1:05 am-11:30 am
1 stop9h 25m
$712
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 10/17
7:11 am-7:23 pm
2 stops14h 12m
Guatemala City La Aurora
Sat 10/31
2:05 pm-12:04 pm
2 stops19h 59m
$721
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sun 10/11
6:06 pm-11:04 am
2 stops18h 58m
Guatemala City La Aurora
Sun 10/18
6:01 am-11:55 pm
2 stops15h 54m
$748
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sun 11/8
5:40 am-12:32 pm
1 stop7h 52m
Guatemala City La Aurora
Thu 11/12
2:11 pm-11:59 pm
1 stop8h 48m
$864
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Fri 10/30
10:43 am-11:26 am
2 stops26h 43m
Guatemala City La Aurora
Fri 11/6
11:57 pm-8:54 pm
2 stops19h 57m
$882
Cheapest one-way
Quickest one-way
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Mon 11/2
7:16 pm-10:23 am
1 stop16h 07m
$393
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Guatemala City in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Knoxville-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Knoxville with our price prediction graph.
TYS-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated August 30, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Knoxville to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
7.1
Boarding
7.7
Food
6.7
Overall
7.4
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Entertainment
7.1
Boarding
7.7
Food
6.7
Overall
7.4
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Entertainment
7.1
Boarding
7.7
Food
6.7
Overall
7.4
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
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Complete your trip
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Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 30, 2026.
Knoxville and Guatemala City flights
Browse other Knoxville and Guatemala City flight options. Last updated on August 30, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on August 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Knoxville to Guatemala City
Discover the top airline that operate flights from Knoxville to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$509 | Average$649 | FlexibilityNo cancel fee | On-time71% |