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Guatemala City

$132+ Cheap flights from Knoxville (TYS) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
ago. 23 — ago. 301
sáb. 8/23
sáb. 8/30
1 adult, Economy
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Cheap flight deals from Knoxville to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 18, 2025.

Round-trip from

$337
(Kiwi.com)

One-way from

$132
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$469
From Knoxville McGhee Tyson to Guatemala City La Aurora
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One-way flight from Knoxville McGhee Tyson to Guatemala City La Aurora
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Highest demand for flights based on searches. 12% potential increase in price ($84 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Knoxville to Guatemala City

Cheapest flights from Knoxville to Guatemala City
Explore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/1411:23 amTYS - GUA
1 stop25h 59mMultiple Airlines
sáb. 10/1812:27 pmGUA - TYS
1 stop29h 44mMultiple Airlines
Deal found 8/17$337
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/2912:45 pmTYS - GUA
2 stops36h 44mMultiple Airlines
sáb. 9/612:20 pmGUA - TYS
1 stop20h 58mMultiple Airlines
Deal found 8/18$346
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/412:08 pmTYS - GUA
1 stop25h 17mMultiple Airlines
jue. 9/1812:20 pmGUA - TYS
2 stops27h 14mMultiple Airlines
Deal found 8/17$375
This Avianca deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/307:25 pmTYS - GUA
1 stop11h 25mMultiple Airlines
sáb. 9/277:05 pmGUA - TYS
1 stop13h 24mMultiple Airlines
Deal found 8/17$523
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/146:03 amTYS - GUA
2 stops15h 03mAmerican Airlines
sáb. 10/182:39 pmGUA - TYS
2 stops17h 52mAmerican Airlines
Deal found 8/17$556

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.

Fly from

Knoxville

Fly to

Guatemala City

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

mar. 10/14

11:23 am-11:22 am

1 stop25h 59m

Guatemala City La Aurora

sáb. 10/18

12:27 pm-8:11 pm

1 stop29h 44m

$337

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

vie. 8/29

12:45 pm-11:29 pm

2 stops36h 44m

Guatemala City La Aurora

sáb. 9/6

12:20 pm-11:18 am

1 stop20h 58m

$346

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

jue. 9/4

12:08 pm-11:25 am

1 stop25h 17m

Guatemala City La Aurora

jue. 9/18

12:20 pm-5:34 pm

2 stops27h 14m

$375

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

sáb. 8/30

7:25 pm-4:50 am

1 stop11h 25m

Guatemala City La Aurora

sáb. 9/27

7:05 pm-10:29 am

1 stop13h 24m

$523

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

vie. 9/19

1:22 pm-11:25 am

2 stops24h 03m

$132

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

jue. 9/18

12:08 pm-11:25 am

1 stop25h 17m

$136

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

mié. 9/24

4:31 pm-11:25 am

1 stop20h 54m

$136

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

lun. 9/22

1:22 pm-11:25 am

2 stops24h 03m

$150

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

sáb. 9/20

4:31 pm-12:05 pm

2 stops21h 34m

$177

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

lun. 9/15

5:27 pm-11:25 am

1 stop19h 58m

$188

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Showing 1-10 of 11 results
1
2

Best time to book a flight from Knoxville to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guatemala City

What is the cheapest month to book a flight from Knoxville to Guatemala City?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Guatemala City (average of $291). Flying from Knoxville to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to GUA?

Find hourly flight availability from Knoxville to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 18, 2025.

It’s typically best to fly out from Knoxville to Guatemala City at noon. Doing so could potentially save you 13% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated agosto 18, 2025.
Get a feel of what it's like to fly with American Airlines from Knoxville to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Food

6.5

Crew

8.0

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Food

6.5

Crew

8.0

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Knoxville to Guatemala City round-trip?

    Currently priced at $463, American Airlines will fly you from Knoxville to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is 24% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guatemala City.

  • Can I find deals for business class flights from Knoxville to Guatemala City?

    Yes. Cheapflights offers flight deals from Knoxville to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Guatemala City?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Guatemala City (average of $291). Flying from Knoxville to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Panajachel
Antigua

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Guatemala City flights
Memphis to Guatemala City flights

Top airline flying from Knoxville to Guatemala City

Discover the top airline that operate flights from Knoxville to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$655FlexibilityNo cancel feeOn-time71%

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