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Guatemala City

$145+ Cheap flights from Knoxville (TYS) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Knoxville to Guatemala City

Cheapest flights from Knoxville to Guatemala City
Explore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/272:23 pmTYS - GUA
2 stops18h 18mMultiple Airlines
Sat 1/33:00 pmGUA - TYS
3 stops28h 26mMultiple Airlines
Deal found 11/12$836
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amTYS - GUA
1 stop9h 40mAmerican Airlines
Sun 1/411:41 amGUA - TYS
1 stop11h 57mAmerican Airlines
Deal found 11/11$1,344
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:05 amTYS - GUA
1 stop13h 34mUnited Airlines
Sat 1/32:10 amGUA - TYS
1 stop8h 01mUnited Airlines
Deal found 11/11$1,533
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:15 pmTYS - GUA
1 stop23h 20mUnited Airlines
Fri 1/22:10 amGUA - TYS
1 stop16h 40mUnited Airlines
Deal found 11/12$1,582
This oojo deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:25 pmTYS - GUA
2 stops14h 35mAvianca
Sun 1/43:45 pmGUA - TYS
2 stops27h 06mAvianca
Deal found 11/11$4,066

Cheap flight deals from Knoxville to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$310
(Kiwi.com)

One-way from

$145
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$854
Provider with most accurate pricing for Knoxville McGhee Tyson-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Guatemala City La Aurora flights.
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From Knoxville McGhee Tyson to Guatemala City La Aurora
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One-way flight from Knoxville McGhee Tyson to Guatemala City La Aurora
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Highest demand for flights based on searches. 18% potential increase in price ($145 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.

Fly from

Knoxville

Fly to

Guatemala City

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 2/4

4:47 pm-12:24 pm

1 stop20h 37m

Guatemala City La Aurora

Sat 2/7

1:28 pm-8:39 am

1 stop18h 11m

$310

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 1/27

7:20 pm-5:00 am

1 stop10h 40m

Guatemala City La Aurora

Tue 2/3

7:10 pm-10:57 am

1 stop14h 47m

$348

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/19

4:23 pm-1:03 pm

2 stops21h 40m

Guatemala City La Aurora

Fri 1/23

1:28 pm-11:09 am

1 stop20h 41m

$383

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 1/27

7:20 pm-7:35 am

2 stops13h 15m

Guatemala City La Aurora

Tue 2/3

8:10 pm-10:57 am

2 stops13h 47m

$496

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/19

7:11 pm-1:13 pm

2 stops19h 02m

Guatemala City La Aurora

Fri 1/23

7:00 am-9:21 pm

2 stops13h 21m

$536

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 3/10

5:30 am-11:45 am

1 stop8h 15m

Guatemala City La Aurora

Wed 3/11

1:10 pm-11:44 pm

1 stop8h 34m

$551

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 1/3

2:23 pm-9:38 am

2 stops44h 15m

$145

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 2/3

7:20 pm-5:00 am

1 stop10h 40m

$146

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 11/27

4:27 pm-11:19 am

2 stops19h 52m

$188

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 11/28

2:59 pm-11:19 am

1 stop21h 20m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 12 results
1
2

Compare providers for flights from Knoxville to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Guatemala City in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Guatemala City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Guatemala City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Guatemala City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guatemala City

What is the cheapest month to book a flight from Knoxville to Guatemala City?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Guatemala City (average of $122). Flying from Knoxville to Guatemala City in September is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Knoxville to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated November 13, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Knoxville to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Guatemala City round-trip?

    Currently priced at $463, American Airlines will fly you from Knoxville to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $504. American Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guatemala City.

  • Can I find deals for business class flights from Knoxville to Guatemala City?

    Yes. Cheapflights offers flight deals from Knoxville to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Guatemala City?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Guatemala City (average of $122). Flying from Knoxville to Guatemala City in September is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Guatemala City flights
Memphis to Guatemala City flights

Top 2 airlines flying from Knoxville to Guatemala City

Discover the top 2 airlines that operate flights from Knoxville to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$655FlexibilityNo cancel feeOn-time71%
DeltaCheapest$504Average$731FlexibilityNo cancel feeOn-timeN/A

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