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Guatemala City

$328+ Cheap flights from Knoxville (TYS) to Guatemala City (GUA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Knoxville to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$280
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$855
From Knoxville McGhee Tyson to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($86 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to Guatemala City

Cheapest flights from Knoxville to Guatemala City
Explore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/174:31 pmTYS - GUA
1 stop20h 54mMultiple Airlines
Wed 9/2412:20 pmGUA - TYS
1 stop20h 58mMultiple Airlines
Deal found 9/10$328
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:26 pmTYS - GUA
1 stop21h 56mMultiple Airlines
Fri 10/3112:27 pmGUA - TYS
1 stop19h 36mMultiple Airlines
Deal found 9/9$353
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2510:53 amTYS - GUA
1 stop26h 29mMultiple Airlines
Sat 11/112:27 pmGUA - TYS
1 stop19h 36mMultiple Airlines
Deal found 9/10$362
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/137:20 amTYS - GUA
2 stops13h 15mMultiple Airlines
Sat 10/47:05 pmGUA - TYS
1 stop13h 24mMultiple Airlines
Deal found 9/11$487
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:30 amTYS - GUA
2 stops11h 05mMultiple Airlines
Sat 11/87:10 pmGUA - TYS
1 stop14h 38mMultiple Airlines
Deal found 9/9$517
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:10 amTYS - GUA
1 stop7h 16mAmerican Airlines
Sat 11/811:34 amGUA - TYS
1 stop11h 25mAmerican Airlines
Deal found 9/9$571

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.

Fly from

Knoxville

Fly to

Guatemala City

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 9/17

4:31 pm-11:25 am

1 stop20h 54m

Guatemala City La Aurora

Wed 9/24

12:20 pm-11:18 am

1 stop20h 58m

$328

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 10/24

3:26 pm-11:22 am

1 stop21h 56m

Guatemala City La Aurora

Fri 10/31

12:27 pm-10:03 am

1 stop19h 36m

$353

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 10/25

10:53 am-11:31 am

2 stops26h 38m

Guatemala City La Aurora

Sat 11/1

12:27 pm-10:03 am

1 stop19h 36m

$386

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 10/1

9:30 am-6:35 pm

2 stops11h 05m

Guatemala City La Aurora

Sat 11/8

7:10 pm-10:48 am

1 stop14h 38m

$517

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 10/1

6:10 am-11:26 am

1 stop7h 16m

Guatemala City La Aurora

Sat 11/8

11:34 am-11:59 pm

1 stop11h 25m

$571

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 12/26

6:00 am-9:34 am

2 stops28h 34m

$349

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 12/27

12:18 pm-11:56 pm

1 stop12h 38m

$363

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 12/26

8:25 am-2:21 pm

1 stop6h 56m

$393

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 12/27

7:23 pm-11:11 pm

2 stops28h 48m

$482

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Knoxville to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guatemala City

What is the cheapest month to book a flight from Knoxville to Guatemala City?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Guatemala City (average of $291). Flying from Knoxville to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to GUA?

Find hourly flight availability from Knoxville to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Knoxville to Guatemala City at noon. Doing so could potentially save you 13% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Knoxville to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with American Airlines from Knoxville to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Overall

7.2

Food

6.4

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Overall

7.2

Food

6.4

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Knoxville to Guatemala City round-trip?

    Currently priced at $482, American Airlines will fly you from Knoxville to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is 21% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Knoxville to Guatemala City one-way?

    The cheapest airlines for a one-way flight from Knoxville to Guatemala City are American Airlines ($363), Delta ($393), and Copa Airlines ($482).

  • Can I find deals for flights from Knoxville to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guatemala City.

  • Can I find deals for business class flights from Knoxville to Guatemala City?

    Yes. Cheapflights offers flight deals from Knoxville to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Guatemala City?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Guatemala City (average of $291). Flying from Knoxville to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Guatemala City flights
Memphis to Guatemala City flights

Top airline flying from Knoxville to Guatemala City

Discover the top airline that operate flights from Knoxville to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$482Average$801FlexibilityNo cancel feeOn-time71%

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