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$141+ Cheap flights from St. Louis to Greenville (STL - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from St. Louis to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$232
(Kiwi.com)

One-way from

$141
(American Airlines)

Popular in

November

Cheapest in

August

Average price

$478
Provider with most accurate pricing for Lambert-St Louis-Greenville flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Greenville flights.
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From Lambert-St Louis to Greenville
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One-way flight from Lambert-St Louis to Greenville
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Highest demand for flights based on searches. 4% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from St. Louis to Greenville

Cheapest flights from St. Louis to Greenville
Explore the most affordable flight options available from St. Louis to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:47 pmSTL - GSP
1 stop22h 23mMultiple Airlines
Mon 12/88:03 pmGSP - STL
1 stop27h 30mMultiple Airlines
Deal found 11/5$232
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:43 pmSTL - GSP
2 stops18h 32mMultiple Airlines
Sat 12/209:41 pmGSP - STL
1 stop14h 15mMultiple Airlines
Deal found 11/4$255
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1710:25 amSTL - GSP
1 stop7h 58mMultiple Airlines
Thu 11/203:56 pmGSP - STL
1 stop9h 01mMultiple Airlines
Deal found 11/6$262
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/212:55 pmSTL - GSP
1 stop5h 15mUnited Airlines
Sat 12/65:28 pmGSP - STL
1 stop5h 12mUnited Airlines
Deal found 11/5$297
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/204:13 pmSTL - GSP
1 stop26h 10mMultiple Airlines
Mon 11/249:53 pmGSP - STL
2 stops17h 36mMultiple Airlines
Deal found 11/5$303
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:30 pmSTL - GSP
1 stop26h 53mMultiple Airlines
Sun 12/2811:33 amGSP - STL
1 stop23h 12mMultiple Airlines
Deal found 11/6$304
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:05 amSTL - GSP
2 stops9h 00mSouthwest
Mon 12/154:45 pmGSP - STL
1 stop6h 15mSouthwest
Deal found 11/5$324

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from St. Louis to Greenville that are best for you.

Fly from

St. Louis

Fly to

Greenville

Route

Depart

Return

Price

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 12/4

2:47 pm-2:10 pm

1 stop22h 23m

Greenville

Mon 12/8

8:03 pm-10:33 pm

1 stop27h 30m

$232

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 12/17

7:43 pm-3:15 pm

2 stops18h 32m

Greenville

Sat 12/20

9:41 pm-10:56 am

1 stop14h 15m

$255

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 12/11

2:47 pm-2:10 pm

1 stop22h 23m

Greenville

Mon 12/15

8:03 pm-10:33 pm

1 stop27h 30m

$262

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 4/7

1:00 pm-6:49 pm

1 stop4h 49m

Greenville

Wed 4/8

6:45 am-11:50 am

1 stop6h 05m

$281

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 1/19

3:11 pm-8:47 pm

1 stop4h 36m

Greenville

Fri 1/23

10:00 am-5:43 pm

2 stops8h 43m

$286

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 12/2

12:55 pm-7:10 pm

1 stop5h 15m

Greenville

Sat 12/6

5:28 pm-9:40 pm

1 stop5h 12m

$297

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 12/9

11:40 am-4:32 pm

1 stop3h 52m

Greenville

Sat 12/13

6:40 am-10:24 am

1 stop4h 44m

$297

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 12/9

12:55 pm-11:59 pm

2 stops10h 04m

Greenville

Sat 12/13

5:28 pm-9:40 pm

1 stop5h 12m

$302

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 11/20

4:13 pm-7:23 pm

1 stop26h 10m

Greenville

Mon 11/24

9:53 pm-2:29 pm

2 stops17h 36m

$303

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 12/11

6:53 pm-11:57 pm

1 stop4h 04m

$141

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 19 results
1
2

Compare providers for flights from St. Louis to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Greenville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Greenville

What is the cheapest month to book a flight from St. Louis to Greenville?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $153). Flying from St. Louis to Greenville in March is currently the most expensive (average of $245). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to GSP?

Find hourly flight availability from St. Louis to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 18% on flights from St. Louis to Greenville by exploring options for tickets at noon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 6, 2025.
See what other customers who have flown with Delta and American Airlines from St. Louis to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Greenville?

    Delta can get you from St. Louis to Greenville in just under 4h 49m. Your travel time can differ by up to . Airlines will cover a distance of 523 mi.

  • What are the cheapest airlines flying from St. Louis to Greenville round-trip?

    According to our current data, Delta ($259), and American Airlines ($271) offers the cheapest pricing from St. Louis to Greenville. Users have found that Delta is 30% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from St. Louis to Greenville one-way?

    $141 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $160 and $189, respectively.

  • Can I find deals for flights from St. Louis to Greenville that include hotel bookings?

    Yes. In addition to deals on St. Louis to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Greenville.

  • Can I find deals for business class flights from St. Louis to Greenville?

    Yes. Cheapflights offers flight deals from St. Louis to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Greenville?

    Currently, February is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $153). Flying from St. Louis to Greenville in March is currently the most expensive (average of $245). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 2 airlines flying from St. Louis to Greenville

Discover the top 2 airlines that operate flights from St. Louis to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$259Average$353FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$406FlexibilityNo cancel feeOn-time71%

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