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Greenville

$184+ Cheap flights from St. Louis to Greenville (STL - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/13. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Cheap flight deals from St. Louis to Greenville

Cheapest flights from St. Louis to Greenville
Explore the most affordable flight options available from St. Louis to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:10 pm
STL
-
GSP
1 stop4h 35m
Southwest
Wed 4/85:05 pm
GSP
-
STL
1 stop3h 10m
Southwest
Deal found 3/9$298
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:59 pm
STL
-
GSP
1 stop25h 39m
Multiple Airlines
Fri 5/85:43 pm
GSP
-
STL
2 stops16h 12m
Multiple Airlines
Deal found 3/10$303
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:30 pm
STL
-
GSP
1 stop6h 10m
Southwest
Tue 5/195:05 pm
GSP
-
STL
1 stop3h 10m
Southwest
Deal found 3/8$312
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:23 am
STL
-
GSP
1 stop10h 15m
Multiple Airlines
Mon 4/68:18 pm
GSP
-
STL
1 stop28h 07m
Multiple Airlines
Deal found 3/10$314
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:55 am
STL
-
GSP
1 stop4h 40m
Southwest
Mon 4/206:25 pm
GSP
-
STL
1 stop5h 50m
Southwest
Deal found 3/9$318
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:30 am
STL
-
GSP
1 stop5h 15m
Southwest
Mon 4/66:25 pm
GSP
-
STL
1 stop6h 40m
Southwest
Deal found 3/10$319
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:45 pm
STL
-
GSP
2 stops7h 30m
Southwest
Mon 4/276:25 pm
GSP
-
STL
1 stop5h 50m
Southwest
Deal found 3/6$324
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:45 pm
STL
-
GSP
2 stops7h 30m
Southwest
Thu 4/306:25 am
GSP
-
STL
2 stops7h 05m
Southwest
Deal found 3/9$329

Find flight deals from St. Louis to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$298
(Southwest)

One-way from

$184
(Southwest)

Popular in

February

Cheapest in

August

Average price

$525
Provider with most accurate pricing for Lambert-St Louis-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Greenville flights.
Search Deals
From Lambert-St Louis to Greenville
Search Deals
One-way flight from Lambert-St Louis to Greenville
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($194 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from St. Louis to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 5/5

2:30 pm-9:40 pm

1 stop6h 10m

Greenville

Tue 5/19

5:05 pm-7:15 pm

1 stop3h 10m

$312

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 4/1

2:15 pm-10:40 pm

2 stops7h 25m

Greenville

Wed 4/8

12:50 pm-8:00 pm

2 stops8h 10m

$313

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sun 5/3

4:59 pm-7:38 pm

1 stop25h 39m

Greenville

Fri 5/8

8:28 pm-12:21 am

1 stop28h 53m

$314

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 4/2

4:55 pm-10:45 pm

1 stop4h 50m

Greenville

Mon 4/6

6:25 pm-12:05 am

1 stop6h 40m

$319

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 4/18

2:25 pm-9:35 pm

2 stops6h 10m

Greenville

Mon 4/20

6:25 pm-11:15 pm

1 stop5h 50m

$323

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 6/6

12:50 pm-8:00 pm

1 stop6h 10m

Greenville

Mon 6/8

6:50 pm-12:35 am

2 stops6h 45m

$348

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 5/21

1:45 pm-10:15 pm

2 stops7h 30m

Greenville

Mon 5/25

6:25 pm-11:15 pm

1 stop5h 50m

$372
Quickest round-trip

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 3/23

4:55 pm-10:45 pm

1 stop4h 50m

Greenville

Tue 5/19

5:05 pm-7:15 pm

1 stop3h 10m

$377

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 5/2

8:45 am-2:15 pm

1 stop4h 30m

Greenville

Tue 5/5

5:45 pm-10:56 pm

1 stop6h 11m

$387
Cheapest one-way
Quickest one-way

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 6/13

5:10 am-1:20 pm

1 stop7h 10m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Sorted by cheapest first

Compare providers for flights from St. Louis to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Greenville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Greenville

What is the cheapest month to book a flight from St. Louis to Greenville?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $137). Flying from St. Louis to Greenville in March is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated March 10, 2026.
See what other customers who have flown with Delta and American Airlines from St. Louis to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,276 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,276 reviews
Delta
7.9
Good
8,276 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,414 reviews
Delta
7.9
Good
8,276 reviews

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Greenville?

    Southwest can get you from St. Louis to Greenville in just under 6h 10m. Your travel time can differ by up to . Airlines will cover a distance of 523 mi.

  • What are the cheapest airlines flying from St. Louis to Greenville round-trip?

    According to our current data, American Airlines ($253), and Delta ($259) offers the cheapest pricing from St. Louis to Greenville. Users have found that American Airlines is 43% cheaper than the other options available to this destination.

  • Can I find deals for flights from St. Louis to Greenville that include hotel bookings?

    Yes. In addition to deals on St. Louis to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Greenville.

  • Can I find deals for business class flights from St. Louis to Greenville?

    Yes. Cheapflights offers flight deals from St. Louis to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Greenville?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $137). Flying from St. Louis to Greenville in March is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from St. Louis to Greenville

Discover the top 2 airlines that operate flights from St. Louis to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$253Average$416FlexibilityNo cancel feeOn-time71%
DeltaCheapest$259Average$358FlexibilityNo cancel feeOn-timeN/A

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