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Greenville

$124+ Cheap flights from St. Louis to Greenville (STL - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from St. Louis to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$270
(Kiwi.com)

One-way from

$124
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$506
Provider with most accurate pricing for Lambert-St Louis-Greenville flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Greenville flights.
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From Lambert-St Louis to Greenville
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One-way flight from Lambert-St Louis to Greenville
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Highest demand for flights based on searches. 6% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from St. Louis to Greenville

Cheapest flights from St. Louis to Greenville
Explore the most affordable flight options available from St. Louis to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:54 amSTL - GSP
1 stop8h 29mMultiple Airlines
Fri 12/198:03 pmGSP - STL
1 stop27h 30mMultiple Airlines
Deal found 11/12$270
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:12 pmSTL - GSP
1 stop4h 23mDelta
Wed 12/37:59 amGSP - STL
1 stop3h 46mDelta
Deal found 11/11$297
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:30 pmSTL - GSP
2 stops45h 40mMultiple Airlines
Fri 12/198:03 pmGSP - STL
1 stop27h 30mMultiple Airlines
Deal found 11/12$304
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:12 pmSTL - GSP
1 stop4h 21mDelta
Sat 12/207:59 pmGSP - STL
1 stop4h 43mDelta
Deal found 11/12$342
This Southwest deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:00 amSTL - GSP
1 stop6h 25mSouthwest
Fri 12/194:20 pmGSP - STL
1 stop8h 15mSouthwest
Deal found 11/12$352
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:12 pmSTL - GSP
1 stop5h 28mDelta
Mon 12/87:36 pmGSP - STL
1 stop5h 06mDelta
Deal found 11/11$354
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:05 amSTL - GSP
1 stop6h 12mDelta
Fri 11/286:15 amGSP - STL
1 stop4h 34mDelta
Deal found 11/10$372
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:00 amSTL - GSP
1 stop6h 10mDelta
Thu 12/411:42 amGSP - STL
1 stop6h 28mDelta
Deal found 11/11$384
This Southwest deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:15 amSTL - GSP
2 stops8h 25mSouthwest
Sat 12/131:55 pmGSP - STL
1 stop8h 05mSouthwest
Deal found 11/12$387
This Southwest deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:40 amSTL - GSP
1 stop7h 00mSouthwest
Thu 12/410:35 amGSP - STL
2 stops8h 55mSouthwest
Deal found 11/11$436

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from St. Louis to Greenville that are best for you.

Fly from

St. Louis

Fly to

Greenville

Route

Depart

Return

Price

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Fri 12/12

9:54 am-7:23 pm

1 stop8h 29m

Greenville

Fri 12/19

8:03 pm-10:33 pm

1 stop27h 30m

$270

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 12/2

5:12 pm-10:35 pm

1 stop4h 23m

Greenville

Wed 12/3

7:59 am-10:45 am

1 stop3h 46m

$297

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sun 12/14

5:12 pm-10:33 pm

1 stop4h 21m

Greenville

Sat 12/20

7:59 pm-11:42 pm

1 stop4h 43m

$342

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 12/6

7:00 am-2:25 pm

1 stop6h 25m

Greenville

Fri 12/19

4:20 pm-11:35 pm

1 stop8h 15m

$352

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 1/1

5:45 am-2:25 pm

1 stop7h 40m

Greenville

Sat 1/3

6:15 pm-12:15 am

1 stop7h 00m

$367

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 1/1

7:00 am-11:58 am

1 stop3h 58m

Greenville

Sat 1/3

6:00 am-9:15 am

1 stop4h 15m

$367

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 12/31

6:00 am-11:58 am

1 stop4h 58m

Greenville

Sat 1/3

6:00 am-9:15 am

1 stop4h 15m

$367

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 12/2

2:38 pm-9:42 pm

1 stop6h 04m

Greenville

Sat 12/13

5:35 am-10:24 am

1 stop5h 49m

$372

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 11/24

7:05 am-2:17 pm

1 stop6h 12m

Greenville

Fri 11/28

6:15 am-9:49 am

1 stop4h 34m

$372

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 12/1

6:00 am-1:10 pm

1 stop6h 10m

Greenville

Thu 12/4

11:42 am-5:10 pm

1 stop6h 28m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 18 results
1
2

Compare providers for flights from St. Louis to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Greenville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Greenville

What is the cheapest month to book a flight from St. Louis to Greenville?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $151). Flying from St. Louis to Greenville in March is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to GSP?

Find hourly flight availability from St. Louis to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 18% on flights from St. Louis to Greenville by exploring options for tickets at noon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 13, 2025.
See what other customers who have flown with Delta and American Airlines from St. Louis to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Greenville?

    Delta and Southwest can get you from St. Louis to Greenville in just under 4h 23m. Your travel time can differ by up to 2h 02m. Airlines will cover a distance of 523 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from St. Louis to Greenville round-trip?

    According to our current data, Delta ($259), and American Airlines ($271) offers the cheapest pricing from St. Louis to Greenville. Users have found that Delta is 30% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from St. Louis to Greenville one-way?

    $199 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $224 and $320, respectively.

  • Can I find deals for flights from St. Louis to Greenville that include hotel bookings?

    Yes. In addition to deals on St. Louis to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Greenville.

  • Can I find deals for business class flights from St. Louis to Greenville?

    Yes. Cheapflights offers flight deals from St. Louis to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Greenville?

    Currently, February is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $151). Flying from St. Louis to Greenville in March is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 2 airlines flying from St. Louis to Greenville

Discover the top 2 airlines that operate flights from St. Louis to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$259Average$353FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$406FlexibilityNo cancel feeOn-time71%

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