HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$146+ Cheap flights from St. Louis to Greenville (STL - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Greenville

Cheapest flights from St. Louis to Greenville
Explore the most affordable flight options available from St. Louis to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/177:10 am
STL
-
GSP
1 stop5h 52m
Delta
Tue 2/245:40 am
GSP
-
STL
1 stop6h 22m
Delta
Deal found 1/19$297
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:47 pm
STL
-
GSP
1 stop3h 56m
Delta
Thu 2/197:40 pm
GSP
-
STL
1 stop4h 56m
Delta
Deal found 1/21$325
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:05 am
STL
-
GSP
1 stop5h 44m
American Airlines
Wed 2/181:49 pm
GSP
-
STL
1 stop4h 09m
American Airlines
Deal found 1/21$328
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/158:30 am
STL
-
GSP
1 stop4h 46m
United Airlines
Thu 2/196:12 am
GSP
-
STL
1 stop5h 46m
United Airlines
Deal found 1/21$342
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:55 pm
STL
-
GSP
1 stop4h 50m
Southwest
Sun 3/297:15 pm
GSP
-
STL
1 stop6h 00m
Southwest
Deal found 1/20$346
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:45 pm
STL
-
GSP
2 stops7h 30m
Southwest
Fri 4/241:50 pm
GSP
-
STL
1 stop6h 55m
Southwest
Deal found 1/19$351
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/156:25 am
STL
-
GSP
2 stops6h 51m
United Airlines
Wed 2/186:12 am
GSP
-
STL
1 stop5h 46m
United Airlines
Deal found 1/21$354
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/411:20 am
STL
-
GSP
1 stop4h 32m
United Airlines
Sat 2/76:35 am
GSP
-
STL
1 stop5h 27m
United Airlines
Deal found 1/21$359
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
-
GSP
2 stops39h 52m
Multiple Airlines
Fri 2/278:18 pm
GSP
-
STL
1 stop28h 41m
Multiple Airlines
Deal found 1/21$360
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/410:10 am
STL
-
GSP
2 stops8h 19m
United Airlines
Sun 2/86:35 am
GSP
-
STL
1 stop6h 54m
United Airlines
Deal found 1/20$364

Find flight deals from St. Louis to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$297
(Delta)

One-way from

$146
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$406
Provider with most accurate pricing for Lambert-St Louis-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Greenville flights.
Search Deals
From Lambert-St Louis to Greenville
Search Deals
One-way flight from Lambert-St Louis to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from St. Louis to Greenville that are best for you.

Fly from

St. Louis

Fly to

Greenville

Route

Depart

Return

Price

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 2/16

6:47 pm-11:43 pm

1 stop3h 56m

Greenville

Thu 2/19

7:40 pm-11:36 pm

1 stop4h 56m

$325

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sun 2/15

8:30 am-2:16 pm

1 stop4h 46m

Greenville

Thu 2/19

6:12 am-10:58 am

1 stop5h 46m

$342

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 4/20

5:00 am-1:15 pm

1 stop7h 15m

Greenville

Fri 4/24

6:25 pm-8:55 pm

1 stop3h 30m

$346

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 3/26

4:55 pm-10:45 pm

1 stop4h 50m

Greenville

Sun 3/29

7:15 pm-12:15 am

1 stop6h 00m

$346

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sun 2/15

6:25 am-2:16 pm

2 stops6h 51m

Greenville

Wed 2/18

6:12 am-10:58 am

1 stop5h 46m

$354

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 2/4

9:59 am-2:03 pm

1 stop3h 04m

Greenville

Sun 2/8

5:40 am-8:53 am

1 stop4h 13m

$359

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Fri 2/20

2:05 pm-7:05 pm

1 stop4h 00m

Greenville

Fri 2/27

7:40 pm-11:25 pm

1 stop4h 45m

$359

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 2/4

11:20 am-4:52 pm

1 stop4h 32m

Greenville

Sat 2/7

6:35 am-11:02 am

1 stop5h 27m

$359

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Fri 2/20

6:47 pm-11:43 pm

1 stop3h 56m

Greenville

Sun 2/22

5:40 am-9:06 am

1 stop4h 26m

$359

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Wed 1/28

5:42 pm-4:15 pm

2 stops21h 33m

$146

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 13 results
1
2

Compare providers for flights from St. Louis to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Greenville flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Greenville

What is the cheapest month to book a flight from St. Louis to Greenville?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $133). Flying from St. Louis to Greenville in March is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 21, 2026.
See what other customers who have flown with Delta and American Airlines from St. Louis to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,088 reviews
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,088 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Greenville?

    Delta, United Airlines, and Southwest can get you from St. Louis to Greenville in just under 3h 56m. Your travel time can differ by up to 3h 19m. Airlines will cover a distance of 523 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from St. Louis to Greenville round-trip?

    According to our current data, Delta ($259), and American Airlines ($271) offers the cheapest pricing from St. Louis to Greenville. Users have found that Delta is 33% cheaper than the other options available to this destination.

  • Can I find deals for flights from St. Louis to Greenville that include hotel bookings?

    Yes. In addition to deals on St. Louis to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Greenville.

  • Can I find deals for business class flights from St. Louis to Greenville?

    Yes. Cheapflights offers flight deals from St. Louis to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Greenville?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Greenville (average of $133). Flying from St. Louis to Greenville in March is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Savannah flights
Kansas City to Charlotte flights
Kansas City to Savannah flights
St. Louis to Charleston flights
Kansas City to Charleston flights
Kansas City to Myrtle Beach flights
St. Louis to Charlotte flights
St. Louis to Myrtle Beach flights
Kansas City to Columbia flights
St. Louis to Columbia flights
Kansas City to Greenville flights
Springfield to Charlotte flights
Springfield to Savannah flights
St. Louis to Hilton Head Island flights
Kansas City to Hilton Head Island flights
Springfield to Charleston flights
Springfield to Myrtle Beach flights
Columbia to Charlotte flights
Kansas City to Augusta flights
Columbia to Charleston flights
St. Louis to Augusta flights
Springfield to Columbia flights
Joplin to Charlotte flights
Springfield to Greenville flights
Joplin to Columbia flights
Joplin to Charleston flights
Springfield to Augusta flights
Springfield to Hilton Head Island flights
Joplin to Savannah flights
Columbia to Myrtle Beach flights
Joplin to Augusta flights
Cape Girardeau to Charlotte flights
Columbia to Hilton Head Island flights
Kansas City to Florence flights
St. Louis to Florence flights
Joplin to Hilton Head Island flights

Top 2 airlines flying from St. Louis to Greenville

Discover the top 2 airlines that operate flights from St. Louis to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$259Average$331FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$406FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.