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$290+ Cheap flights from Santa Fe to Greenville (SAF - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — GSP
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Santa Fe to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$454
(United Airlines)

One-way from

$290
(American Airlines)
From Santa Fe to Greenville
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One-way flight from Santa Fe to Greenville
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Find flight deals from Santa Fe to Greenville

Cheapest flights from Santa Fe to Greenville
Explore the most affordable flight options available from Santa Fe to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/267:15 amSAF - GSP
1 stop5h 48mUnited Airlines
Thu 8/74:25 pmGSP - SAF
1 stop7h 33mUnited Airlines
Deal found 6/12$454

Cheapflights Fare Finder

Customize your flight search to find flights from Santa Fe to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Santa Fe to Greenville that are best for you.

Fly from

Santa Fe

Fly to

Greenville

Route

Depart

Return

Price

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Thu 6/26

7:15 am-3:03 pm

1 stop5h 48m

Greenville

Thu 8/7

4:25 pm-9:58 pm

1 stop7h 33m

$454

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Mon 9/15

2:05 pm-10:30 pm

1 stop6h 25m

$290

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Mon 9/15

7:15 am-9:01 pm

3 stops11h 46m

$664

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Santa Fe to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Greenville

What is the cheapest month to book a flight from Santa Fe to Greenville?

Currently, January is the cheapest month in which you can book a flight from Santa Fe to Greenville (average of $329). Flying from Santa Fe to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated June 12, 2025.
United Airlines
7.4
Good
8,790 reviews

Entertainment

7.0

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,790 reviews
United Airlines
7.4
Good
8,790 reviews

Entertainment

7.0

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,790 reviews

Entertainment

7.0

Crew

8.1

Overall

7.4

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Santa Fe to Greenville that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Greenville.

  • Can I find deals for business class flights from Santa Fe to Greenville?

    Yes. Cheapflights offers flight deals from Santa Fe to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Santa Fe to Greenville (average of $329). Flying from Santa Fe to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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