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$329+ Cheap flights from Santa Fe to Charleston (SAF - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — CHS
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from Santa Fe to Charleston

Cheapest flights from Santa Fe to Charleston
Explore the most affordable flight options available from Santa Fe to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:36 pm
SAF
-
CHS
1 stop8h 05m
American Airlines
Sat 5/167:00 am
CHS
-
SAF
1 stop8h 34m
American Airlines
Deal found 4/27$449
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:05 am
SAF
-
CHS
2 stops11h 24m
American Airlines
Wed 6/33:43 pm
CHS
-
SAF
1 stop8h 09m
American Airlines
Deal found 4/27$524
This KAYAK deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/192:04 pm
SAF
-
CHS
1 stop6h 37m
American Airlines
Wed 5/207:00 am
CHS
-
SAF
1 stop8h 34m
American Airlines
Deal found 4/27$613
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:20 pm
SAF
-
CHS
2 stops24h 46m
United Airlines
Sat 12/127:40 pm
CHS
-
SAF
2 stops19h 00m
United Airlines
Deal found 4/26$750
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:36 pm
SAF
-
CHS
1 stop8h 05m
American Airlines
Sun 5/105:00 am
CHS
-
SAF
2 stops10h 34m
American Airlines
Deal found 4/27$942

Find flight deals from Santa Fe to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$449
(American Airlines)

One-way from

$329
(American Airlines)
Provider with most accurate pricing for Santa Fe-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Fe-Charleston flights.
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From Santa Fe to Charleston
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One-way flight from Santa Fe to Charleston
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Santa Fe to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 5/12

12:36 pm-10:41 pm

1 stop8h 05m

Charleston

Sat 5/16

7:00 am-1:34 pm

1 stop8h 34m

$449

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Wed 5/27

12:58 pm-10:58 pm

1 stop8h 00m

Charleston

Wed 6/3

3:43 pm-9:52 pm

1 stop8h 09m

$449
Quickest round-trip

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 5/19

2:04 pm-10:41 pm

1 stop6h 37m

Charleston

Wed 5/20

7:00 am-1:34 pm

1 stop8h 34m

$613
Cheapest one-way
Quickest one-way

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 6/9

6:05 am-2:53 pm

1 stop6h 48m

$329

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Mon 6/8

3:19 pm-8:51 am

2 stops15h 32m

$458

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 6/9

6:00 pm-2:06 pm

3 stops18h 06m

$617

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Santa Fe-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Fe-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Fe-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Fe-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Fe-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Fe to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Fe to Charleston?

    Airlines like American Airlines fly from Santa Fe to Charleston in about 8h 05m. The time it takes to get you to your destination can typically vary by up to . Santa Fe and Charleston are separated by a distance of 1494 mi.

  • Can I find deals for flights from Santa Fe to Charleston that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Charleston.

  • Can I find deals for business class flights from Santa Fe to Charleston?

    Yes. Cheapflights offers flight deals from Santa Fe to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Walterboro
Summerville
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach

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