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$249+ Cheap flights from Madison to Greenville (MSN - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
MSN — GSP
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Madison to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Madison (MSN) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$249
(Delta)

Popular in

December

Cheapest in

April

Average price

$408
From Madison Truax Field to Greenville
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Madison to Greenville

Cheapest flights from Madison to Greenville
Explore the most affordable flight options available from Madison to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:05 amMSN - GSP
1 stop6h 25mDelta
Wed 11/193:32 pmGSP - MSN
1 stop5h 42mDelta
Deal found 9/15$249
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/51:53 pmMSN - GSP
1 stop5h 07mAmerican Airlines
Wed 11/196:01 amGSP - MSN
2 stops8h 22mAmerican Airlines
Deal found 9/15$254
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/303:51 pmMSN - GSP
1 stop6h 07mAmerican Airlines
Sat 10/46:33 pmGSP - MSN
1 stop5h 54mAmerican Airlines
Deal found 9/14$259
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:40 amMSN - GSP
1 stop6h 48mDelta
Sat 9/275:21 pmGSP - MSN
1 stop6h 37mDelta
Deal found 9/15$309
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2310:50 amMSN - GSP
2 stops11h 10mUnited Airlines
Sat 9/275:34 pmGSP - MSN
1 stop5h 54mUnited Airlines
Deal found 9/15$314
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/238:10 amMSN - GSP
2 stops7h 02mAmerican Airlines
Sat 9/2712:20 pmGSP - MSN
2 stops6h 34mAmerican Airlines
Deal found 9/15$319
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:30 amMSN - GSP
2 stops6h 41mUnited Airlines
Mon 10/135:34 pmGSP - MSN
1 stop5h 54mUnited Airlines
Deal found 9/15$324
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/302:46 pmMSN - GSP
1 stop5h 32mUnited Airlines
Sat 10/45:34 pmGSP - MSN
1 stop5h 54mUnited Airlines
Deal found 9/15$329
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2012:50 pmMSN - GSP
1 stop5h 23mAmerican Airlines
Mon 9/226:33 pmGSP - MSN
1 stop5h 54mAmerican Airlines
Deal found 9/16$339

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madison to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Madison to Greenville that are best for you.

Fly from

Madison

Fly to

Greenville

Route

Depart

Return

Price

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Wed 2/18

3:50 pm-10:18 pm

1 stop5h 28m

Greenville

Sat 2/21

7:15 am-1:01 pm

1 stop6h 46m

$249

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Wed 11/5

7:05 am-2:30 pm

1 stop6h 25m

Greenville

Wed 11/19

3:32 pm-8:14 pm

1 stop5h 42m

$249

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Wed 11/5

1:53 pm-8:00 pm

1 stop5h 07m

Greenville

Wed 11/19

6:01 am-1:23 pm

2 stops8h 22m

$254

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Tue 9/30

8:10 am-5:00 pm

1 stop7h 50m

Greenville

Sat 10/4

8:05 am-1:30 pm

2 stops6h 25m

$264

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Wed 2/18

1:04 pm-11:59 pm

2 stops9h 55m

Greenville

Sat 2/21

10:00 am-7:08 pm

2 stops10h 08m

$304

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Sat 11/8

4:34 pm-11:58 pm

2 stops6h 24m

Greenville

Fri 11/21

8:00 am-12:44 pm

1 stop5h 44m

$319

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Mon 9/29

12:50 pm-7:13 pm

1 stop5h 23m

$264

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Sun 9/28

7:59 pm-6:46 pm

3 stops21h 47m

$288

MadisonGreenville

MSN - GSP

MSNGSP

Madison Truax Field

Sun 9/28

1:17 pm-7:55 pm

1 stop5h 38m

$344

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Madison to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Madison with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madison to Greenville

What is the cheapest month to book a flight from Madison to Greenville?

Currently, August is the cheapest month in which you can book a flight from Madison to Greenville (average of $321). Flying from Madison to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Madison to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Madison to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madison to Greenville?

    Airlines like Delta and American Airlines fly from Madison to Greenville in about 5h 07m. The time it takes to get you to your destination can typically vary by up to 21m. There are 684 mi between Madison and Greenville. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Madison to Greenville round-trip?

    Cheapflights users have booked flights from Madison to Greenville round-trip from $162. Other airlines that can offer you cheap pricing are American Airlines, from $198, and United Airlines, from $213. You may be able to fly from Madison to Greenville for 62% less than the average price by searching for these airlines.

  • Can I find deals for flights from Madison to Greenville that include hotel bookings?

    Yes. In addition to deals on Madison to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madison to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madison to Greenville.

  • Can I find deals for business class flights from Madison to Greenville?

    Yes. Cheapflights offers flight deals from Madison to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madison to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Madison to Greenville (average of $321). Flying from Madison to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 3 airlines flying from Madison to Greenville

Discover the top 3 airlines that operate flights from Madison to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$162Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$380FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$213Average$438FlexibilityNo cancel feeOn-time69%

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