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$209+ Cheap flights from Islip to Greenville (ISP - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — GSP
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Islip to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$209
(Southwest)

Popular in

October

Cheapest in

April

Average price

$331
From Islip Long Island to Greenville
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Islip to Greenville

Cheapest flights from Islip to Greenville
Explore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/115:40 amISP - GSP
1 stop4h 20mSouthwest
mar. 11/184:45 pmGSP - ISP
1 stop5h 20mSouthwest
Deal found 9/11$209
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/115:40 amISP - GSP
1 stop4h 20mSouthwest
sáb. 11/158:10 amGSP - ISP
1 stop3h 40mSouthwest
Deal found 9/11$224
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/265:50 pmISP - GSP
1 stop4h 05mSouthwest
lun. 12/18:20 pmGSP - ISP
1 stop3h 35mSouthwest
Deal found 9/10$397
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/1012:35 pmISP - GSP
1 stop8h 50mSouthwest
vie. 10/171:50 pmGSP - ISP
1 stop9h 55mSouthwest
Deal found 9/10$400
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/2311:40 amISP - GSP
2 stops9h 04mBreeze Airways
jue. 10/308:03 pmGSP - ISP
1 stop22h 25mBreeze Airways
Deal found 9/11$526

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Islip to Greenville that are best for you.

Fly from

Islip

Fly to

Greenville

Route

Depart

Return

Price

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

mar. 11/11

5:40 am-10:00 am

1 stop4h 20m

Greenville

mar. 11/18

4:45 pm-10:05 pm

1 stop5h 20m

$209

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

mar. 11/11

5:40 am-4:05 pm

2 stops10h 25m

Greenville

sáb. 11/15

8:10 am-11:50 am

1 stop3h 40m

$230

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

jue. 1/29

6:00 am-10:40 am

1 stop4h 40m

Greenville

mar. 2/3

11:15 am-9:55 pm

2 stops10h 40m

$245

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

vie. 1/30

6:00 am-10:40 am

1 stop4h 40m

Greenville

mar. 2/3

11:15 am-9:55 pm

2 stops10h 40m

$261

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

vie. 1/30

6:00 am-10:40 am

1 stop4h 40m

Greenville

lun. 2/2

11:15 am-9:55 pm

2 stops10h 40m

$316

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

mié. 11/26

5:50 pm-9:55 pm

1 stop4h 05m

Greenville

lun. 12/1

8:20 pm-11:55 pm

1 stop3h 35m

$397

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

mar. 10/14

6:00 am-6:30 pm

2 stops12h 30m

$324

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

vie. 10/17

8:47 pm-9:53 am

2 stops37h 06m

$398

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Islip to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Greenville

What is the cheapest month to book a flight from Islip to Greenville?

Currently, August is the cheapest month in which you can book a flight from Islip to Greenville (average of $322). Flying from Islip to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated septiembre 11, 2025.
See what other customers who have flown with Southwest from Islip to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Islip to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Islip to Greenville?

    For as low as $209, Southwest can have you in Greenville from Islip in 4h 20m. The distance between Islip and Greenville is about 642 mi.

  • What is the cheapest airline to fly from Islip to Greenville round-trip?

    Currently priced at $218, Southwest will fly you from Islip to Greenville and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. You may be able to fly from Islip to Greenville for 38% less than the average price by searching for this airline.

  • Can I find deals for flights from Islip to Greenville that include hotel bookings?

    Yes. In addition to deals on Islip to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Greenville.

  • Can I find deals for business class flights from Islip to Greenville?

    Yes. Cheapflights offers flight deals from Islip to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Islip to Greenville (average of $322). Flying from Islip to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top airline flying from Islip to Greenville

Discover the top airline that operate flights from Islip to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$218Average$386FlexibilityNo cancel feeOn-time63%

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