HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$184+ Cheap flights from Islip, NY to Greenville (ISP - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — GSP
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Islip to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Islip to Greenville

Cheapest flights from Islip to Greenville
Explore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amISP - GSP
1 stop28h 53mMultiple Airlines
Fri 12/198:03 pmGSP - ISP
1 stop21h 52mMultiple Airlines
Deal found 12/13$359
This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2912:40 pmISP - GSP
1 stop9h 15mSouthwest
Wed 12/314:45 pmGSP - ISP
1 stop5h 20mSouthwest
Deal found 12/14$492
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:30 amISP - GSP
1 stop4h 25mSouthwest
Fri 1/28:20 pmGSP - ISP
1 stop3h 35mSouthwest
Deal found 12/13$532
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:20 pmISP - GSP
2 stops27h 35mMultiple Airlines
Thu 1/15:17 pmGSP - ISP
1 stop6h 14mMultiple Airlines
Deal found 12/14$545
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:35 pmISP - GSP
1 stop22h 48mMultiple Airlines
Thu 1/15:17 pmGSP - ISP
1 stop6h 14mMultiple Airlines
Deal found 12/14$589
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:35 pmISP - GSP
1 stop22h 48mMultiple Airlines
Tue 12/304:43 pmGSP - ISP
1 stop7h 16mMultiple Airlines
Deal found 12/14$645
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:25 amISP - GSP
2 stops12h 10mMultiple Airlines
Thu 1/15:17 pmGSP - ISP
1 stop6h 14mMultiple Airlines
Deal found 12/14$677

Find flight deals from Islip to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$346
(Southwest)

One-way from

$184
(Southwest)

Popular in

December

Cheapest in

April

Average price

$756
Provider with most accurate pricing for Islip Long Island-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Islip Long Island-Greenville flights.
Search Deals
From Islip Long Island to Greenville
Search Deals
One-way flight from Islip Long Island to Greenville
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($170 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Islip to Greenville that are best for you.

Fly from

Islip

Fly to

Greenville

Route

Depart

Return

Price

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 2/20

5:35 pm-9:45 pm

1 stop4h 10m

Greenville

Tue 2/24

10:05 am-4:15 pm

1 stop6h 10m

$346

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Tue 1/13

3:45 pm-7:50 pm

1 stop4h 05m

Greenville

Tue 1/20

11:15 am-9:55 pm

2 stops10h 40m

$361

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 2/27

5:35 am-10:10 am

1 stop4h 35m

Greenville

Sun 3/1

7:40 pm-11:30 pm

1 stop3h 50m

$367

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 1/16

5:55 am-10:10 am

1 stop4h 15m

Greenville

Sun 1/18

6:15 pm-9:55 pm

1 stop3h 40m

$407

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Thu 6/4

9:10 am-1:15 pm

1 stop4h 05m

Greenville

Sun 6/7

7:55 am-11:45 am

1 stop3h 50m

$417

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Tue 1/13

3:45 pm-7:50 pm

1 stop4h 05m

$184

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Mon 1/12

3:45 pm-7:50 pm

1 stop4h 05m

$194

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Tue 1/13

8:00 am-9:25 am

3 stops49h 25m

$241

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Compare providers for flights from Islip to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to Greenville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Islip, New York-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Islip, New York-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Islip, New York-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Islip, New York-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Islip to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Greenville

What is the cheapest month to book a flight from Islip, New York to Greenville?

Currently, March is the cheapest month in which you can book a flight from Islip, New York to Greenville (average of $37). Flying from Islip, New York to Greenville in December is currently the most expensive (average of $85). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated December 15, 2025.
See what other customers who have flown with Southwest from Islip to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Islip to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Islip, New York to Greenville?

    Airlines like Southwest fly from Islip, New York to Greenville in about 4h 10m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 642 mi.

  • What is the cheapest airline to fly from Islip, New York to Greenville round-trip?

    Flying on Southwest is currently your cheapest option to Greenville, with prices starting at $218. Southwest is currently priced 45% below the average price you’ll pay for this route.

  • Can I find deals for flights from Islip to Greenville that include hotel bookings?

    Yes. In addition to deals on Islip to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Greenville.

  • Can I find deals for business class flights from Islip to Greenville?

    Yes. Cheapflights offers flight deals from Islip to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Greenville?

    Currently, March is the cheapest month in which you can book a flight from Islip, New York to Greenville (average of $37). Flying from Islip, New York to Greenville in December is currently the most expensive (average of $85). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Islip to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
Newark to Charlotte flights
LaGuardia to Charlotte flights
John F Kennedy Intl to Charleston flights
LaGuardia to Charleston flights
Newark to Charleston flights
John F Kennedy Intl to Savannah flights
Newark to Savannah flights
LaGuardia to Savannah flights
Newark to Myrtle Beach flights
John F Kennedy Intl to Myrtle Beach flights
LaGuardia to Myrtle Beach flights
LaGuardia to Greenville flights
Newark to Greenville flights
John F Kennedy Intl to Greenville flights
Albany to Charlotte flights
White Plains to Charleston flights
Stewart to Charlotte flights
Stewart to Charleston flights
Newark to Columbia flights
Syracuse to Charlotte flights
Islip to Charleston flights
LaGuardia to Columbia flights
Syracuse to Myrtle Beach flights
White Plains to Charlotte flights
Buffalo to Myrtle Beach flights
John F Kennedy Intl to Columbia flights
Albany to Myrtle Beach flights
White Plains to Myrtle Beach flights
Newark to Hilton Head Island flights
Albany to Savannah flights
Islip to Charlotte flights
Rochester to Charleston flights
John F Kennedy Intl to Augusta flights
Rochester to Charlotte flights
John F Kennedy Intl to Hilton Head Island flights
Stewart to Myrtle Beach flights
Syracuse to Greenville flights
Newark to Augusta flights
Rochester to Savannah flights
Buffalo to Charlotte flights
Syracuse to Savannah flights
Syracuse to Charleston flights
Buffalo to Savannah flights
LaGuardia to Hilton Head Island flights
LaGuardia to Augusta flights
Rochester to Myrtle Beach flights
Buffalo to Charleston flights
White Plains to Savannah flights
Albany to Charleston flights

Top airline flying from Islip to Greenville

Discover the top airline that operate flights from Islip to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$218Average$386FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.