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$163+ Cheap flights from Islip, NY to Greenville (ISP - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — GSP
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Islip to Greenville

Cheapest flights from Islip to Greenville
Explore the most affordable flight options available from Islip to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:30 pmISP - GSP
1 stop4h 05mSouthwest
Mon 11/174:45 pmGSP - ISP
1 stop5h 20mSouthwest
Deal found 10/28$447
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amISP - GSP
1 stop4h 00mSouthwest
Wed 11/54:45 pmGSP - ISP
1 stop5h 20mSouthwest
Deal found 10/28$667
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3011:40 amISP - GSP
2 stops9h 04mBreeze Airways
Sun 11/28:03 pmGSP - ISP
1 stop22h 25mBreeze Airways
Deal found 10/26$768
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:40 amISP - GSP
2 stops9h 34mBreeze Airways
Sun 11/98:03 pmGSP - ISP
1 stop22h 25mBreeze Airways
Deal found 10/26$859

Cheap flight deals from Islip to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Islip (ISP) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$447
(Southwest)

One-way from

$163
(Kiwi.com)

Popular in

September

Cheapest in

April

Average price

$462
Provider with most accurate pricing for Islip Long Island-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Islip Long Island-Greenville flights.
Search Deals
From Islip Long Island to Greenville
Search Deals
One-way flight from Islip Long Island to Greenville
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Islip to Greenville that are best for you.

Fly from

Islip

Fly to

Greenville

Route

Depart

Return

Price

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 11/14

5:30 pm-9:35 pm

1 stop4h 05m

Greenville

Mon 11/17

4:45 pm-10:05 pm

1 stop5h 20m

$447

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Sat 11/8

8:45 pm-9:53 am

1 stop13h 08m

$163

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Sat 11/8

4:58 pm-9:16 am

2 stops40h 18m

$245

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Compare providers for flights from Islip to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Islip to Greenville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Islip, New York-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Islip, New York-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Islip, New York-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Islip, New York-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Islip, New York-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Islip to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Greenville

What is the cheapest month to book a flight from Islip, New York to Greenville?

Currently, March is the cheapest month in which you can book a flight from Islip, New York to Greenville (average of $37). Flying from Islip, New York to Greenville in August is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 29, 2025.
See what other customers who have flown with Southwest from Islip to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Islip to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Islip, New York to Greenville?

    Airlines like Southwest fly from Islip, New York to Greenville in about 4h 05m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 642 mi.

  • What is the cheapest airline to fly from Islip, New York to Greenville round-trip?

    Flying on Southwest is currently your cheapest option to Greenville, with prices starting at $218. Southwest is currently priced 40% below the average price you’ll pay for this route.

  • Can I find deals for flights from Islip to Greenville that include hotel bookings?

    Yes. In addition to deals on Islip to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Greenville.

  • Can I find deals for business class flights from Islip to Greenville?

    Yes. Cheapflights offers flight deals from Islip to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Greenville?

    Currently, March is the cheapest month in which you can book a flight from Islip, New York to Greenville (average of $37). Flying from Islip, New York to Greenville in August is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top airline flying from Islip to Greenville

Discover the top airline that operate flights from Islip to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$218Average$386FlexibilityNo cancel feeOn-time63%

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