How popular is this Denver to Greenville flight route?

Within the past month, 2 users have taken a look at flights from Denver Intl to Greenville.

How long is the flight from Denver to Greenville?

Delta and United Airlines can get you from Denver to Greenville in just under 5h 17m. Your travel time can differ by up to 2h 15m. Airlines will cover a distance of 1275 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Denver to Greenville round-trip?

Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $198. Additional round-trip tickets that might be worth considering are offered by Delta and Southwest, with the lowest prices starting at $236 and $268, respectively. These flights start at 52% lower than the current average price 3 months from now.

What are the cheapest airlines to fly from Denver to Greenville one-way?

The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $134. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Denver to Greenville for a low price.

Weekly flight availability from Denver to Greenville

The most flights from DEN to GSP are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What are the cheapest flights from Denver to Greenville?

While on average a flight from Denver to Greenville is generally $536, our data shows the cheapest flight currently is $154. When looking at the most popular route, (Denver Intl - Greenville), you can expect to pay $208 for that flight.

What are the most popular airlines that fly from Denver to Greenville?

United Airlines, American Airlines and Delta are the most popular airlines when flying from Denver to Greenville.

Most accurate provider : When it comes to deals on Denver-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Denver-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Denver-Greenville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Denver-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Denver to Greenville?

If you book a flight from Denver to Greenville, you will be flying from Denver Intl to Greenville. Flights to Greenville (GSP) from Denver Intl (DEN) take 2h 56m for a nonstop flight. There is 1 flight from Denver Intl to Greenville per day from 4 airlines.

Can I find deals for flights from Denver to Greenville that include hotel bookings?

Yes. In addition to deals on Denver to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Denver to Greenville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Greenville.

Can I find deals for business class flights from Denver to Greenville?

Yes. Cheapflights offers flight deals from Denver to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$108+ Flights from Denver to Greenville

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Find cheap flights from Denver to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Denver Intl to Greenville are usually found in February or August, booked 82 days in advance, depart on a Saturday or Tuesday and return on a Thursday

Cheap flight deals from Denver to Greenville

Cheapest flights from Denver to Greenville
Explore the most affordable flight options available from Denver to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Tue 12/3011:59 pmDEN - GSP

1 stop6h 37mAmerican Airlines

Fri 1/25:00 amGSP - DEN

1 stop6h 20mAmerican Airlines

Deal found 12/11

$299

Thu 12/1810:46 amDEN - GSP

2 stops32h 28mMultiple Airlines

Mon 1/53:34 pmGSP - DEN

1 stop30h 25mMultiple Airlines

Deal found 12/10

$311

Tue 12/307:45 amDEN - GSP

1 stop7h 16mUnited Airlines

Mon 1/58:34 amGSP - DEN

1 stop9h 18mUnited Airlines

Deal found 12/10

$323

Tue 12/306:25 amDEN - GSP

2 stops31h 30mMultiple Airlines

Mon 1/58:03 pmGSP - DEN

1 stop28h 56mMultiple Airlines

Deal found 12/10

$342

Thu 12/189:53 amDEN - GSP

Nonstop3h 15mUnited Airlines

Mon 1/55:44 pmGSP - DEN

1 stop8h 00mUnited Airlines

Deal found 12/10

$344

Sun 12/2811:59 pmDEN - GSP

1 stop6h 37mAmerican Airlines

Mon 1/56:20 pmGSP - DEN

1 stop6h 11mAmerican Airlines

Deal found 12/10

$384

Sun 12/218:10 pmDEN - GSP

1 stop11h 55mSouthwest

Sat 1/38:00 pmGSP - DEN

1 stop6h 25mSouthwest

Deal found 12/10

$389

Sun 12/2110:10 amDEN - GSP

1 stop7h 14mAmerican Airlines

Sat 1/35:00 amGSP - DEN

1 stop6h 20mAmerican Airlines

Deal found 12/10

$413

Fri 12/197:20 amDEN - GSP

1 stop6h 20mSouthwest

Sun 12/214:20 pmGSP - DEN

1 stop9h 55mSouthwest

Deal found 12/9

$418

Mon 12/299:53 amDEN - GSP

Nonstop3h 15mUnited Airlines

Sun 1/45:36 pmGSP - DEN

1 stop8h 02mUnited Airlines

Deal found 12/10

$430

Sat 12/207:50 pmDEN - GSP

1 stop12h 15mSouthwest

Thu 1/13:05 pmGSP - DEN

1 stop9h 10mSouthwest

Deal found 12/10

$438

Best flights from Denver to Greenville
Discover carefully curated flight deals from Denver to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Fri 2/273:07 pmDEN - GSP

1 stop5h 17mDelta

Fri 3/67:40 pmGSP - DEN

1 stop6h 45mDelta

Deal found 12/10

$269

Wed 1/711:15 amDEN - GSP

1 stop7h 32mUnited Airlines

Wed 1/1410:00 amGSP - DEN

1 stop6h 46mUnited Airlines

Deal found 12/10

$269

Fri 1/306:15 amDEN - GSP

1 stop12h 44mMultiple Airlines

Sun 2/15:45 pmGSP - DEN

2 stops20h 34mMultiple Airlines

Deal found 12/11

$284

Tue 12/3011:59 pmDEN - GSP

1 stop6h 37mAmerican Airlines

Fri 1/25:00 amGSP - DEN

1 stop6h 20mAmerican Airlines

Deal found 12/10

$299

Fri 1/307:00 amDEN - GSP

1 stop8h 35mSouthwest

Sun 2/112:30 pmGSP - DEN

2 stops9h 20mSouthwest

Deal found 12/10

$310

Fri 1/162:42 pmDEN - GSP

1 stop7h 13mDelta

Mon 1/197:46 pmGSP - DEN

1 stop6h 42mDelta

Deal found 12/10

$269

Thu 1/16:00 amDEN - GSP

1 stop6h 15mUnited Airlines

Thu 1/810:00 amGSP - DEN

1 stop8h 37mUnited Airlines

Deal found 12/11

$269

Fri 1/306:00 amDEN - GSP

1 stop6h 03mDelta

Sun 2/17:46 pmGSP - DEN

1 stop6h 42mDelta

Deal found 12/10

$269

Sat 1/172:40 pmDEN - GSP

1 stop5h 44mDelta

Mon 1/195:12 pmGSP - DEN

1 stop6h 02mDelta

Deal found 12/11

$269

Last-minute flights from Denver to Greenville
Discover last-minute flight deals from Denver to Greenville. Data last updated December 12, 2025 and is based on user searches.

Tue 12/3011:59 pmDEN - GSP

1 stop6h 37mAmerican Airlines

Fri 1/25:00 amGSP - DEN

1 stop6h 20mAmerican Airlines

Deal found 12/11

$299

Wed 1/710:05 amDEN - GSP

Nonstop3h 15mUnited Airlines

Wed 1/144:50 pmGSP - DEN

1 stop7h 16mUnited Airlines

Deal found 12/10

$259

Thu 1/84:13 pmDEN - GSP

1 stop26h 46mMultiple Airlines

Thu 1/154:43 pmGSP - DEN

2 stops45h 35mMultiple Airlines

Deal found 12/10

$286

Sat 1/1010:05 amDEN - GSP

Nonstop3h 15mUnited Airlines

Sat 1/174:15 pmGSP - DEN

Nonstop3h 56mUnited Airlines

Deal found 12/11

$275

Sat 1/106:20 amDEN - GSP

1 stop11h 30mSouthwest

Sat 1/1710:50 amGSP - DEN

2 stops11h 20mSouthwest

Deal found 12/11

$296

Sat 1/1712:52 pmDEN - GSP

2 stops8h 59mAmerican Airlines

Mon 1/195:40 pmGSP - DEN

1 stop5h 36mAmerican Airlines

Deal found 12/10

$274

Wed 1/2111:20 amDEN - GSP

1 stop26h 59mMultiple Airlines

Mon 1/269:49 pmGSP - DEN

1 stop23h 10mMultiple Airlines

Deal found 12/10

$208

Wed 1/2110:35 amDEN - GSP

2 stops7h 15mSouthwest

Mon 1/2610:05 amGSP - DEN

2 stops11h 30mSouthwest

Deal found 12/10

$295

Fri 1/239:41 amDEN - GSP

1 stop8h 26mMultiple Airlines

Sun 1/256:45 pmGSP - DEN

2 stops29h 02mMultiple Airlines

Deal found 12/11

$270

Fri 1/306:00 amDEN - GSP

1 stop6h 03mDelta

Sun 2/17:46 pmGSP - DEN

1 stop6h 42mDelta

Deal found 12/10

$269

Fri 1/306:15 amDEN - GSP

1 stop12h 44mMultiple Airlines

Sun 2/15:45 pmGSP - DEN

2 stops20h 34mMultiple Airlines

Deal found 12/11

$284

One-way flights from Denver to Greenville
Search for one-way flight options from Denver to Greenville. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Sat 1/1011:59 pmDEN - GSP

1 stop14h 20mMultiple Airlines

Deal found 12/10

$108

Sun 2/15:30 amDEN - GSP

1 stop4h 25mSouthwest

Deal found 12/10

$135

Sun 2/11:50 pmDEN - GSP

2 stops17h 08mMultiple Airlines

Deal found 12/10

$136

Thu 12/1810:46 amDEN - GSP

2 stops32h 28mMultiple Airlines

Deal found 12/9

$171

Thu 12/185:50 amDEN - GSP

1 stop7h 50mSouthwest

Deal found 12/10

$189

Fri 12/196:05 amDEN - GSP

2 stops36h 46mMultiple Airlines

Deal found 12/10

$201

Wed 12/248:10 amDEN - GSP

1 stop5h 55mSouthwest

Deal found 12/10

$214

Find flight deals from Denver to Greenville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$208 (Kiwi.com)
One-way from	$108 (Kiwi.com)
Popular in	December
Cheapest in	February
Average price	$505
Good round-trip deal	$335 or less
Good one-way deal	$253 or less

Provider with most accurate pricing for Denver Intl-Greenville flight deals.

Search Deals

Provider most trusted by Cheapflights users for Denver Intl-Greenville flights.

Search Deals

From Denver Intl to Greenville

Search Deals

One-way flight from Denver Intl to Greenville

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($38 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Denver Intl to Greenville.

Search Deals

Price to beat on a one-way flight from Denver Intl to Greenville.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 2/27

3:07 pm-10:24 pm

1 stop5h 17m

Greenville

Fri 3/6

7:40 pm-12:25 am

1 stop6h 45m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Wed 1/7

11:15 am-8:47 pm

1 stop7h 32m

Greenville

Wed 1/14

10:00 am-2:46 pm

1 stop6h 46m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 1/16

2:42 pm-11:55 pm

1 stop7h 13m

Greenville

Mon 1/19

7:46 pm-12:28 am

1 stop6h 42m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Thu 1/1

6:00 am-2:15 pm

1 stop6h 15m

Greenville

Thu 1/8

10:00 am-4:37 pm

1 stop8h 37m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 1/30

6:00 am-2:03 pm

1 stop6h 03m

Greenville

Sun 2/1

7:46 pm-12:28 am

1 stop6h 42m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Sat 1/17

2:40 pm-10:24 pm

1 stop5h 44m

Greenville

Mon 1/19

5:12 pm-9:14 pm

1 stop6h 02m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 1/30

6:15 am-8:59 pm

1 stop12h 44m

Greenville

Sun 2/1

5:45 pm-12:19 pm

2 stops20h 34m

$284

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Tue 12/30

11:59 pm-8:36 am

1 stop6h 37m

Greenville

Fri 1/2

5:00 am-9:20 am

1 stop6h 20m

$299

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 1/30

7:00 am-5:35 pm

1 stop8h 35m

Greenville

Sun 2/1

12:30 pm-7:50 pm

2 stops9h 20m

$310

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Sat 1/10

6:43 pm-4:19 pm

2 stops19h 36m

$116

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 17 results

Compare providers for flights from Denver to Greenville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Greenville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Denver-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Denver-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Denver-Greenville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Denver-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Denver with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Greenville

Prices

Airlines

How far ahead should I book a flight from Denver to Greenville?

Booking 25 days in advance of your planned departure date is, on average, the best time to get cheap flights from Denver to Greenville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Denver to Greenville?

Currently, April is the cheapest month in which you can book a flight from Denver to Greenville (average of $62). Flying from Denver to Greenville in December is currently the most expensive (average of $138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to GSP?

It’s typically best to fly out from Denver to Greenville in the evening. Doing so could potentially save you 30% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Denver to Greenville?

Travelers seeking maximum savings on their Denver to Greenville flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Greenville

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Denver to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,095 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airports do I use to fly from Denver to Greenville?
If you book a flight from Denver to Greenville, you will be flying from Denver Intl to Greenville. Flights to Greenville (GSP) from Denver Intl (DEN) take 2h 56m for a nonstop flight. There is 1 flight from Denver Intl to Greenville per day from 4 airlines.
How popular is this Denver to Greenville flight route?
Within the past month, 2 users have taken a look at flights from Denver Intl to Greenville.
How long is the flight from Denver to Greenville?
Delta and United Airlines can get you from Denver to Greenville in just under 5h 17m. Your travel time can differ by up to 2h 15m. Airlines will cover a distance of 1275 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Denver to Greenville round-trip?
Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $198. Additional round-trip tickets that might be worth considering are offered by Delta and Southwest, with the lowest prices starting at $236 and $268, respectively. These flights start at 52% lower than the current average price 3 months from now.
What are the cheapest airlines to fly from Denver to Greenville one-way?
The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $134. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Denver to Greenville for a low price.
What are the cheapest flights from Denver to Greenville?
While on average a flight from Denver to Greenville is generally $536, our data shows the cheapest flight currently is $154. When looking at the most popular route, (Denver Intl - Greenville), you can expect to pay $208 for that flight.
Can I find deals for flights from Denver to Greenville that include hotel bookings?
Yes. In addition to deals on Denver to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Denver to Greenville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Greenville.
Can I find deals for business class flights from Denver to Greenville?
Yes. Cheapflights offers flight deals from Denver to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Denver to Greenville?
Currently, April is the cheapest month in which you can book a flight from Denver to Greenville (average of $62). Flying from Denver to Greenville in December is currently the most expensive (average of $138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to Greenville

Top 4 airlines flying from Denver to Greenville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$198	Average$364	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$236	Average$327	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$268	Average$469	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$269	Average$492	FlexibilityNo cancel fee	On-time69%

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$108+ Cheap flights from Denver to Greenville (DEN - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Denver to Greenville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Denver Intl to Greenville are usually found in February or August, booked 82 days in advance, depart on a Saturday or Tuesday and return on a Thursday

Cheap flight deals from Denver to Greenville

Cheapest flights from Denver to GreenvilleExplore the most affordable flight options available from Denver to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Denver to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Denver to Greenville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Greenville that are best for you.

Compare providers for flights from Denver to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Greenville in December.

Best time to book a flight from Denver to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Denver with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Denver to Greenville

How far ahead should I book a flight from Denver to Greenville?

What is the cheapest month to book a flight from Denver to Greenville?

What is the cheapest time of day to fly from DEN to GSP?

What is the cheapest day to fly from Denver to Greenville?

Weekly flight availability from Denver to Greenville

Reviews of airlines servicing Greenville

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Denver to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Denver to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Denver to Greenville?

How popular is this Denver to Greenville flight route?

How long is the flight from Denver to Greenville?

What are the cheapest airlines flying from Denver to Greenville round-trip?

What are the cheapest airlines to fly from Denver to Greenville one-way?

What are the cheapest flights from Denver to Greenville?

Can I find deals for flights from Denver to Greenville that include hotel bookings?

How can I find direct flights from Denver to Greenville?

Can I find deals for business class flights from Denver to Greenville?

What is the cheapest month to book a flight from Denver to Greenville?

Traveling to a place near Greenville?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Greenville

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Top 4 airlines flying from Denver to Greenville

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Cheapest flights from Denver to Greenville
Explore the most affordable flight options available from Denver to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.