$132+ Cheap flights from Buffalo to Greenville (BUF - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Greenville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Greenville
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Cheapest flights from Buffalo to GreenvilleExplore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:08 am -
1 stop4h 20m
Tue 10/205:56 pm -
1 stop5h 36m
Deal found 9/21![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop4h 50m
Fri 11/136:00 am -
1 stop7h 26m
Deal found 9/18![Delta logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:53 pm -
1 stop7h 06m
Mon 10/268:32 pm -
2 stops40h 43m
Deal found 9/21![Multiple Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:45 pm -
2 stops8h 05m
Fri 11/138:15 am -
1 stop6h 10m
Deal found 9/18![Southwest logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:08 am -
1 stop4h 20m
Mon 10/264:10 pm -
1 stop6h 40m
Deal found 9/21![American Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:15 am -
1 stop3h 30m
Sat 10/246:40 am -
2 stops7h 55m
Deal found 9/19![Southwest logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:56 pm -
1 stop3h 57m
Mon 10/264:10 pm -
1 stop6h 40m
Deal found 9/22![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2612:07 pm -
1 stop5h 47m
Fri 1/17:21 am -
1 stop4h 06m
Deal found 9/19![Delta logo]()
$373
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:15 am -
1 stop4h 33m
Fri 1/17:21 am -
1 stop4h 06m
Deal found 9/19![Delta logo]()
$383
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:06 pm -
1 stop4h 40m
Mon 11/306:26 pm -
1 stop4h 06m
Deal found 9/18![American Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:50 pm -
1 stop6h 45m
Sun 11/16:40 am -
2 stops7h 45m
Deal found 9/22![Southwest logo]()
$398
Best flights from Buffalo to GreenvilleDiscover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop4h 50m
Fri 11/136:00 am -
1 stop7h 26m
Deal found 9/18![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:45 pm -
2 stops8h 05m
Fri 11/138:15 am -
1 stop6h 10m
Deal found 9/18![Southwest logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:30 am -
2 stops10h 35m
Sat 10/107:35 pm -
1 stop4h 15m
Deal found 9/19![United Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:50 pm -
1 stop6h 45m
Sun 11/16:40 am -
2 stops7h 45m
Deal found 9/22![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2711:40 am -
1 stop5h 39m
Wed 3/36:00 am -
1 stop4h 26m
Deal found 9/19![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:35 am -
1 stop3h 36m
Mon 11/167:19 pm -
1 stop4h 40m
Deal found 9/21![Delta logo]()
$434
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
2 stops6h 10m
Sat 10/246:40 am -
2 stops7h 55m
Deal found 9/19![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:20 pm -
2 stops11h 05m
Tue 12/12:50 pm -
1 stop3h 20m
Deal found 9/18![Southwest logo]()
$414
Last-minute flights from Buffalo to GreenvilleDiscover last-minute flight deals from Buffalo to Greenville. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Greenville. Data last updated September 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
1 stop4h 42m
Sat 10/105:56 pm -
1 stop5h 36m
Deal found 9/19![American Airlines logo]()
$403
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:30 am -
2 stops10h 35m
Sat 10/107:35 pm -
1 stop4h 15m
Deal found 9/19![United Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:08 am -
1 stop4h 20m
Tue 10/205:56 pm -
1 stop5h 36m
Deal found 9/21![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:53 pm -
1 stop7h 06m
Tue 10/2011:28 am -
2 stops25h 31m
Deal found 9/21![Multiple Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:15 am -
1 stop3h 30m
Sat 10/246:40 am -
2 stops7h 55m
Deal found 9/19![Southwest logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:53 pm -
1 stop7h 06m
Mon 10/268:32 pm -
2 stops40h 43m
Deal found 9/21![Multiple Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:08 am -
1 stop4h 20m
Mon 10/264:10 pm -
1 stop6h 40m
Deal found 9/21![American Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:53 pm -
1 stop7h 06m
Sun 10/253:18 pm -
2 stops21h 41m
Deal found 9/21![Multiple Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:56 pm -
1 stop3h 57m
Mon 10/264:10 pm -
1 stop6h 40m
Deal found 9/22![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:50 pm -
1 stop6h 45m
Sun 11/16:40 am -
2 stops7h 45m
Deal found 9/22![Southwest logo]()
$398
One-way flights from Buffalo to GreenvilleSearch for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:00 pm -
2 stops23h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:44 pm -
2 stops30h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$148
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:08 am -
1 stop4h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![American Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/71:15 pm -
2 stops26h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:44 pm -
2 stops30h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$175
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:35 pm -
2 stops8h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Southwest logo]()
$192
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:50 am -
1 stop4h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$199
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:50 am -
1 stop4h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$209
Find flight deals from Buffalo to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (American Airlines) |
One-way from | $132 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $312 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Tue 10/20
10:00 am-5:19 pm
1 stop7h 19m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Wed 10/28
6:08 am-10:28 am
1 stop4h 20m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Mon 12/7
6:00 am-11:13 am
1 stop5h 13m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Fri 10/23
3:53 pm-9:27 pm
1 stop5h 34m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$175
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Tue 10/20
12:35 pm-9:05 pm
2 stops8h 30m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$192
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sun 11/8
3:59 pm-10:51 pm
1 stop6h 52m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sun 11/1
10:00 am-2:58 pm
1 stop4h 58m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sun 11/1
11:00 am-8:10 pm
2 stops9h 10m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$231
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sun 11/8
11:00 am-8:10 pm
2 stops9h 10m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$240
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Mon 10/19
2:20 pm-10:50 pm
2 stops8h 30m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$240
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
BUF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Greenville
Prices
More
What is the cheapest month to book a flight from Buffalo to Greenville?
Currently, September is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $312). Flying from Buffalo to Greenville in December is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to Greenville?
Airfare is below average for this route at the moment.
Buffalo to Greenville flights typically cost between $348 and $638 in October.The cheapest round-trip price found within the last 5 days was $309 on American Airlines (Oct 15-Oct 20).
What’s the top layover airport for flights from Buffalo to Greenville?
Share of 1-stop round-trip flights from Buffalo to Greenville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Washington, D.C. (DCA) – chosen by Cheapflights users on 40% of 1-stop itineraries from Buffalo to Greenville on Cheapflights.
What’s the cheapest layover airport for flights from Buffalo to Greenville?
Average round-trip fare for 1-stop flights from Buffalo to Greenville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
New York (LGA) is the most affordable 1-stop option, with an average round-trip price of $284.
What’s the fastest layover option from Buffalo to Greenville?
Shortest average travel time for 1-stop one-way flights from Buffalo to Greenville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Washington, D.C. (DCA) have the shortest average one-way travel time for 1-stop routes: 4h 27m.
Which airport typically offers the quickest layover for flights from Buffalo to Greenville?
Average layover duration for 1-stop one-way flights from Buffalo to Greenville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (DCA) offer the fastest connection on this route, with an average layover time of 0h 51m.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 23, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Alternative routes for Buffalo to Greenville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Greenville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to Greenville by cabin class
Find flights from Buffalo to Greenville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 23, 2026.
Buffalo and Greenville flights
Browse other Buffalo and Greenville flight options. Last updated on September 23, 2026.
Other flights from Buffalo
Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on September 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Buffalo to Greenville
Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$346 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$406 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$302 | Average$414 | FlexibilityNo cancel fee | On-timeN/A |