$145+ Cheap flights from Buffalo to Greenville (BUF - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Nov 21 — Nov 281
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Greenville
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Best
Last-minute
One-way
Cheapest flights from Buffalo to GreenvilleExplore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:40 am -
1 stop4h 29m
Tue 11/174:01 pm -
1 stop6h 43m
Deal found 10/20![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:55 pm -
1 stop4h 00m
Sun 12/68:15 am -
1 stop6h 10m
Deal found 10/19![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:00 am -
1 stop5h 04m
Mon 1/45:45 pm -
1 stop5h 13m
Deal found 10/21![Delta logo]()
$304
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am -
1 stop5h 13m
Sun 12/67:00 am -
1 stop4h 05m
Deal found 10/20![Delta logo]()
$324
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:13 am -
1 stop5h 38m
Sun 11/157:00 am -
1 stop3h 40m
Deal found 10/19![American Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
1 stop4h 10m
Sun 11/228:15 am -
1 stop6h 10m
Deal found 10/21![Southwest logo]()
$353
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:35 am -
2 stops10h 23m
Tue 11/176:20 am -
2 stops7h 50m
Deal found 10/20![United Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop4h 27m
Mon 11/96:18 pm -
1 stop4h 15m
Deal found 10/21![American Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
2 stops6h 12m
Sun 11/227:00 am -
1 stop3h 42m
Deal found 10/21![American Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:44 pm -
1 stop3h 47m
Wed 11/256:26 pm -
1 stop4h 11m
Deal found 10/20![American Airlines logo]()
$396
Best flights from Buffalo to GreenvilleDiscover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:50 am -
1 stop4h 20m
Mon 2/18:30 am -
1 stop6h 35m
Deal found 10/20![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am -
1 stop5h 13m
Sun 12/67:00 am -
1 stop4h 05m
Deal found 10/20![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop4h 02m
Mon 11/235:40 am -
2 stops8h 40m
Deal found 10/17![United Airlines logo]()
$422
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
1 stop4h 10m
Sun 11/228:15 am -
1 stop6h 10m
Deal found 10/21![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:06 pm -
1 stop6h 24m
Tue 12/1512:18 pm -
1 stop5h 18m
Deal found 10/17![Delta logo]()
$417
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
2 stops8h 16m
Mon 11/97:43 pm -
1 stop4h 03m
Deal found 10/21![United Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1812:50 pm -
1 stop4h 51m
Sat 3/273:00 pm -
1 stop5h 18m
Deal found 10/17![Delta logo]()
$417
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:55 am -
2 stops8h 15m
Fri 1/12:50 pm -
1 stop3h 20m
Deal found 10/18![Southwest logo]()
$422
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:25 am -
2 stops6h 45m
Tue 12/157:05 am -
2 stops10h 35m
Deal found 10/17![Southwest logo]()
$427
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:00 am -
1 stop4h 50m
Tue 11/177:20 am -
1 stop3h 58m
Deal found 10/17![Delta logo]()
$427
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:20 am -
2 stops9h 30m
Sun 12/68:15 am -
1 stop6h 10m
Deal found 10/19![Southwest logo]()
$429
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:55 am -
2 stops8h 15m
Sat 1/28:10 am -
1 stop3h 45m
Deal found 10/17![Southwest logo]()
$452
Last-minute flights from Buffalo to GreenvilleDiscover last-minute flight deals from Buffalo to Greenville. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Greenville. Data last updated October 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop4h 27m
Mon 11/96:18 pm -
1 stop4h 15m
Deal found 10/21![American Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:40 am -
1 stop4h 29m
Tue 11/174:01 pm -
1 stop6h 43m
Deal found 10/20![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:35 am -
2 stops10h 23m
Tue 11/176:20 am -
2 stops7h 50m
Deal found 10/20![United Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:00 am -
1 stop4h 50m
Tue 11/177:20 am -
1 stop3h 58m
Deal found 10/17![Delta logo]()
$427
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:13 am -
1 stop5h 38m
Sun 11/157:00 am -
1 stop3h 40m
Deal found 10/19![American Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
1 stop4h 10m
Sun 11/228:15 am -
1 stop6h 10m
Deal found 10/21![Southwest logo]()
$353
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
2 stops6h 12m
Sun 11/227:00 am -
1 stop3h 42m
Deal found 10/21![American Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:56 am -
1 stop6h 11m
Mon 11/2311:19 am -
1 stop6h 43m
Deal found 10/17![American Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop4h 02m
Mon 11/235:40 am -
2 stops8h 40m
Deal found 10/17![United Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:44 pm -
1 stop3h 47m
Wed 11/256:26 pm -
1 stop4h 11m
Deal found 10/20![American Airlines logo]()
$396
One-way flights from Buffalo to GreenvilleSearch for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
1 stop4h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:47 pm -
3 stops25h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:15 pm -
2 stops44h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$198
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
2 stops6h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$205
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:16 am -
1 stop6h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![American Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/122:10 pm -
2 stops8h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Southwest logo]()
$244
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:20 pm -
2 stops11h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$250
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:13 am -
1 stop5h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:00 am -
1 stop6h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$269
Find flight deals from Buffalo to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (American Airlines) |
One-way from | $145 (Southwest) |
Popular in | December |
Cheapest in | September |
Average price | $395 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Fri 12/4
3:55 pm-7:55 pm
1 stop4h 00m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sun 11/15
6:00 am-10:10 am
1 stop4h 10m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sun 11/15
6:47 pm-8:12 pm
3 stops25h 25m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$189
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sun 11/15
6:00 am-12:12 pm
2 stops6h 12m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Fri 3/12
5:55 pm-9:58 pm
1 stop4h 03m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
Quickest round-trip
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Wed 12/30
7:47 pm-11:39 pm
1 stop3h 52m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Thu 12/10
5:55 am-2:10 pm
2 stops8h 15m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$214
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Wed 12/30
12:20 pm-11:25 pm
2 stops11h 05m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$250
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sun 11/8
5:13 am-10:50 am
1 stop5h 37m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$259
BuffaloGreenville
BUF Buffalo - GSP Greenville
BUFGSP
Buffalo
Sat 1/30
5:50 am-10:10 am
1 stop4h 20m
Greenville
Mon 2/1
8:30 am-3:05 pm
1 stop6h 35m
$269
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
BUF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Greenville
Prices
More
What is the cheapest month to book a flight from Buffalo to Greenville?
Currently, September is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $312). Flying from Buffalo to Greenville in December is currently the most expensive (average of $564). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to Greenville?
Airfare is below average for this route at the moment.
Buffalo to Greenville flights typically cost between $376 and $473 in November.The cheapest round-trip price found within the last 5 days was $269 on American Airlines (Nov 10-Nov 17).
What’s the top layover airport for flights from Buffalo to Greenville?
Share of 1-stop round-trip flights from Buffalo to Greenville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Washington, D.C. (DCA) – chosen by Cheapflights users on 40% of 1-stop itineraries from Buffalo to Greenville on Cheapflights.
What’s the cheapest layover airport for flights from Buffalo to Greenville?
Average round-trip fare for 1-stop flights from Buffalo to Greenville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
New York (LGA) is the most affordable 1-stop option, with an average round-trip price of $284.
What’s the fastest layover option from Buffalo to Greenville?
Shortest average travel time for 1-stop one-way flights from Buffalo to Greenville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Washington, D.C. (DCA) have the shortest average one-way travel time for 1-stop routes: 4h 27m.
Which airport typically offers the quickest layover for flights from Buffalo to Greenville?
Average layover duration for 1-stop one-way flights from Buffalo to Greenville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (DCA) offer the fastest connection on this route, with an average layover time of 0h 51m.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 22, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Entertainment
7.4
Crew
8.6
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Entertainment
7.4
Crew
8.6
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Entertainment
7.4
Crew
8.6
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Entertainment
7.4
Crew
8.6
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Top 3 airlines flying from Buffalo to Greenville
Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$341 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$294 | Average$406 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$302 | Average$414 | FlexibilityNo cancel fee | On-timeN/A |