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$112+ Cheap flights from Buffalo to Greenville (BUF - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Buffalo to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$223
(Delta)

One-way from

$112
(Delta)

Popular in

September

Cheapest in

June

Average price

$328
Provider with most accurate pricing for Buffalo-Greenville flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Greenville flights.
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From Buffalo to Greenville
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One-way flight from Buffalo to Greenville
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Highest demand for flights based on searches. 2% potential increase in price ($10 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Buffalo to Greenville

Cheapest flights from Buffalo to Greenville
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/172:58 pmBUF - GSP
1 stop7h 15mDelta
Tue 2/245:40 amGSP - BUF
1 stop5h 20mDelta
Deal found 1/7$223
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:00 amBUF - GSP
1 stop5h 03mDelta
Tue 2/1011:30 amGSP - BUF
1 stop5h 34mDelta
Deal found 1/7$247
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:24 amBUF - GSP
1 stop4h 55mAmerican Airlines
Tue 2/248:46 amGSP - BUF
2 stops7h 08mAmerican Airlines
Deal found 1/7$269
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:32 amBUF - GSP
1 stop6h 42mDelta
Mon 3/211:36 amGSP - BUF
1 stop5h 22mDelta
Deal found 1/6$271
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:00 amBUF - GSP
1 stop12h 27mAmerican Airlines
Tue 2/106:00 amGSP - BUF
1 stop6h 08mAmerican Airlines
Deal found 1/6$279
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/75:44 pmBUF - GSP
1 stop4h 40mDelta
Tue 2/106:45 pmGSP - BUF
1 stop4h 12mDelta
Deal found 1/7$281
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/76:00 amBUF - GSP
1 stop5h 30mDelta
Mon 2/96:45 pmGSP - BUF
1 stop4h 12mDelta
Deal found 1/7$284
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/712:35 pmBUF - GSP
2 stops8h 10mAmerican Airlines
Mon 2/96:05 amGSP - BUF
1 stop4h 52mAmerican Airlines
Deal found 1/6$289
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/65:47 pmBUF - GSP
1 stop4h 57mDelta
Tue 2/105:59 pmGSP - BUF
1 stop4h 53mDelta
Deal found 1/7$295
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:33 pmBUF - GSP
2 stops5h 29mAmerican Airlines
Thu 4/96:00 amGSP - BUF
1 stop5h 14mAmerican Airlines
Deal found 1/6$296
This American Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:00 amBUF - GSP
1 stop5h 14mAmerican Airlines
Wed 4/86:00 amGSP - BUF
1 stop5h 14mAmerican Airlines
Deal found 1/8$303

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.

Fly from

Buffalo

Fly to

Greenville

Route

Depart

Return

Price

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 2/5

6:00 am-11:03 am

1 stop5h 03m

Greenville

Tue 2/10

11:30 am-5:04 pm

1 stop5h 34m

$247

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 4/7

10:44 am-5:44 pm

1 stop7h 00m

Greenville

Thu 4/9

6:00 am-11:14 am

1 stop5h 14m

$247

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 2/5

5:47 pm-10:44 pm

1 stop4h 57m

Greenville

Mon 2/9

11:30 am-5:04 pm

1 stop5h 34m

$271

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 2/2

6:00 am-10:50 am

1 stop4h 50m

Greenville

Mon 2/9

6:45 pm-10:57 pm

1 stop4h 12m

$271

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:00 am-12:14 pm

1 stop5h 14m

Greenville

Wed 4/8

6:00 am-11:14 am

1 stop5h 14m

$279

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 2/7

5:44 pm-10:24 pm

1 stop4h 40m

Greenville

Tue 2/10

6:45 pm-10:57 pm

1 stop4h 12m

$281

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 2/6

6:00 am-6:27 pm

1 stop12h 27m

Greenville

Tue 2/10

6:00 am-12:08 pm

2 stops6h 08m

$284

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 2/7

6:00 am-11:30 am

1 stop5h 30m

Greenville

Mon 2/9

6:45 pm-10:57 pm

1 stop4h 12m

$284

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Wed 2/11

5:47 pm-10:44 pm

1 stop4h 57m

$112

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Wed 2/11

5:12 am-10:30 am

1 stop5h 18m

$112

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 18 results
1
2

Compare providers for flights from Buffalo to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Greenville

What is the cheapest month to book a flight from Buffalo to Greenville?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $103). Flying from Buffalo to Greenville in November is currently the most expensive (average of $208). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 8, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,250 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,032 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,097 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Greenville?

    Delta and American Airlines can get you from Buffalo to Greenville in just under 5h 03m. Your travel time can differ by up to 1h 57m. The distance between Buffalo and Greenville is about 586 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to Greenville round-trip?

    Our cheapest airline available from Buffalo to Greenville is American Airlines. Our recent data shows that you can find tickets from as low as $198 on this airline. Additional options worth looking into are Delta and Southwest, starting at $236 and $277 round-trip. You may be able to fly from Buffalo to Greenville for 46% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Greenville that include hotel bookings?

    Yes. In addition to deals on Buffalo to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Greenville.

  • Can I find deals for business class flights from Buffalo to Greenville?

    Yes. Cheapflights offers flight deals from Buffalo to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $103). Flying from Buffalo to Greenville in November is currently the most expensive (average of $208). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Buffalo to Greenville

Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$329FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$316FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$277Average$406FlexibilityNo cancel feeOn-time63%

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