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$141+ Cheap flights from Buffalo to Greenville (BUF - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Buffalo to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$277
(Delta)

One-way from

$141
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$415
From Buffalo to Greenville
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One-way flight from Buffalo to Greenville
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Highest demand for flights based on searches. 1% potential increase in price ($4 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Buffalo to Greenville

Cheapest flights from Buffalo to Greenville
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:30 pmBUF - GSP
1 stop4h 25mDelta
Tue 10/217:30 amGSP - BUF
1 stop4h 39mDelta
Deal found 9/16$277
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:38 pmBUF - GSP
1 stop4h 13mAmerican Airlines
Tue 10/141:35 pmGSP - BUF
1 stop4h 43mAmerican Airlines
Deal found 9/14$287
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:33 pmBUF - GSP
2 stops6h 25mAmerican Airlines
Tue 11/117:38 pmGSP - BUF
1 stop4h 06mAmerican Airlines
Deal found 9/16$292
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:30 pmBUF - GSP
1 stop4h 25mDelta
Sat 10/259:45 amGSP - BUF
1 stop5h 43mDelta
Deal found 9/16$297
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:30 pmBUF - GSP
1 stop4h 25mDelta
Tue 10/287:30 amGSP - BUF
1 stop4h 39mDelta
Deal found 9/16$302
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:38 pmBUF - GSP
1 stop4h 13mAmerican Airlines
Mon 10/136:11 amGSP - BUF
1 stop4h 59mAmerican Airlines
Deal found 9/15$312
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:00 amBUF - GSP
1 stop11h 00mAmerican Airlines
Wed 10/157:11 pmGSP - BUF
1 stop4h 31mAmerican Airlines
Deal found 9/15$316
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:49 pmBUF - GSP
1 stop4h 52mDelta
Sun 11/25:30 amGSP - BUF
1 stop5h 31mDelta
Deal found 9/15$322
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:30 pmBUF - GSP
1 stop4h 25mDelta
Tue 10/287:30 amGSP - BUF
1 stop4h 39mDelta
Deal found 9/16$328
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:20 amBUF - GSP
1 stop4h 28mDelta
Sun 10/126:35 amGSP - BUF
1 stop4h 26mDelta
Deal found 9/15$332

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.

Fly from

Buffalo

Fly to

Greenville

Route

Depart

Return

Price

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 10/14

7:30 pm-11:55 pm

1 stop4h 25m

Greenville

Tue 10/21

7:30 am-12:09 pm

1 stop4h 39m

$277

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 10/13

5:11 am-10:20 am

1 stop5h 09m

Greenville

Wed 10/15

6:00 am-12:24 pm

1 stop6h 24m

$287

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 11/8

12:38 pm-5:41 pm

1 stop5h 03m

Greenville

Tue 11/11

6:13 pm-11:01 pm

1 stop4h 48m

$287

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 10/25

5:14 pm-10:18 pm

1 stop5h 04m

Greenville

Tue 10/28

3:26 pm-10:57 pm

1 stop7h 31m

$287

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 11/8

5:33 pm-11:58 pm

2 stops6h 25m

Greenville

Tue 11/11

7:38 pm-11:44 pm

1 stop4h 06m

$292

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 12/8

5:05 am-10:33 am

1 stop5h 28m

Greenville

Mon 12/15

7:30 am-12:05 pm

1 stop4h 35m

$297

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 10/20

7:30 pm-11:55 pm

1 stop4h 25m

Greenville

Sat 10/25

9:45 am-3:28 pm

1 stop5h 43m

$297

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Wed 10/29

12:49 pm-5:41 pm

1 stop4h 52m

Greenville

Sun 11/2

5:30 am-11:01 am

1 stop5h 31m

$322

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 10/21

6:00 am-10:09 am

1 stop4h 09m

Greenville

Sun 10/26

5:30 am-11:01 am

1 stop5h 31m

$322

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sun 10/26

6:00 am-10:45 am

1 stop4h 45m

Greenville

Sat 11/1

1:39 pm-7:52 pm

1 stop6h 13m

$333

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 20 results
1
2

Best time to book a flight from Buffalo to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Greenville

What is the cheapest month to book a flight from Buffalo to Greenville?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $321). Flying from Buffalo to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to GSP?

Find hourly flight availability from Buffalo to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

One of the essential ways to save on airfare from Buffalo to Greenville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 29% on airfare.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,926 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Greenville?

    Delta and American Airlines can get you from Buffalo to Greenville in just under 4h 25m. Your travel time can differ by up to 44m. The distance between Buffalo and Greenville is about 586 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to Greenville round-trip?

    Our cheapest airline available from Buffalo to Greenville is American Airlines. Our recent data shows that you can find tickets from as low as $198 on this airline. Additional options worth looking into are Delta and Southwest, starting at $216 and $218 round-trip. You may be able to fly from Buffalo to Greenville for 43% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Greenville that include hotel bookings?

    Yes. In addition to deals on Buffalo to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Greenville.

  • Can I find deals for business class flights from Buffalo to Greenville?

    Yes. Cheapflights offers flight deals from Buffalo to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $321). Flying from Buffalo to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 4 airlines flying from Buffalo to Greenville

Discover the top 4 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$321FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$312FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$218Average$386FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$278Average$402FlexibilityNo cancel feeOn-time69%

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