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$184+ Cheap flights from Buffalo to Greenville (BUF - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Buffalo to Greenville

Cheapest flights from Buffalo to Greenville
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:30 amBUF - GSP
1 stop4h 45mAmerican Airlines
Fri 11/285:15 amGSP - BUF
1 stop5h 47mAmerican Airlines
Deal found 10/28$307
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/223:27 pmBUF - GSP
1 stop5h 28mAmerican Airlines
Fri 11/285:15 amGSP - BUF
1 stop5h 47mAmerican Airlines
Deal found 10/26$332
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amBUF - GSP
1 stop3h 39mAmerican Airlines
Mon 12/16:40 pmGSP - BUF
1 stop5h 28mAmerican Airlines
Deal found 10/27$337
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:26 amBUF - GSP
1 stop10h 49mAmerican Airlines
Sat 11/156:13 pmGSP - BUF
1 stop5h 55mAmerican Airlines
Deal found 10/27$391
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1110:50 amBUF - GSP
1 stop6h 03mUnited Airlines
Sat 11/1512:23 pmGSP - BUF
2 stops10h 35mUnited Airlines
Deal found 10/27$416

Cheap flight deals from Buffalo to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$297
(Southwest)

One-way from

$184
(Delta)

Popular in

December

Cheapest in

January

Average price

$362
Provider with most accurate pricing for Buffalo-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Greenville flights.
Search Deals
From Buffalo to Greenville
Search Deals
One-way flight from Buffalo to Greenville
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.

Fly from

Buffalo

Fly to

Greenville

Route

Depart

Return

Price

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 2/21

5:21 am-12:19 pm

2 stops6h 58m

Greenville

Tue 2/24

1:49 pm-5:53 pm

1 stop4h 04m

$287

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 1/12

5:50 am-10:40 am

1 stop4h 50m

Greenville

Mon 1/19

6:35 pm-10:30 pm

1 stop3h 55m

$297

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 1/16

11:50 am-5:56 pm

1 stop6h 06m

Greenville

Sun 1/18

6:00 am-11:25 am

1 stop5h 25m

$307

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 11/27

5:30 am-10:15 am

1 stop4h 45m

Greenville

Fri 11/28

5:15 am-11:02 am

1 stop5h 47m

$307

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 2/6

6:00 am-6:27 pm

1 stop12h 27m

Greenville

Tue 2/10

7:16 am-12:08 pm

1 stop4h 52m

$321

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 11/22

3:27 pm-8:55 pm

1 stop5h 28m

Greenville

Fri 11/28

5:15 am-11:02 am

1 stop5h 47m

$332

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 11/24

6:00 am-11:26 am

1 stop5h 26m

Greenville

Mon 12/1

6:40 pm-12:08 am

1 stop5h 28m

$337

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/10

10:30 am-5:32 pm

1 stop7h 02m

$184

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/10

5:51 pm-11:11 pm

2 stops5h 20m

$189

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sun 3/8

12:09 pm-6:49 pm

1 stop6h 40m

$194

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 13 results
1
2

Compare providers for flights from Buffalo to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Greenville

What is the cheapest month to book a flight from Buffalo to Greenville?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $63). Flying from Buffalo to Greenville in December is currently the most expensive (average of $197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to GSP?

Find hourly flight availability from Buffalo to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

One of the essential ways to save on airfare from Buffalo to Greenville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 28% on airfare.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 29, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,992 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Greenville?

    American Airlines and Southwest can get you from Buffalo to Greenville in just under 4h 50m. Your travel time can differ by up to 2h 08m. The distance between Buffalo and Greenville is about 586 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to Greenville round-trip?

    Our cheapest airline available from Buffalo to Greenville is American Airlines. Our recent data shows that you can find tickets from as low as $198 on this airline. Additional options worth looking into are Delta and Southwest, starting at $236 and $277 round-trip. You may be able to fly from Buffalo to Greenville for 44% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Greenville that include hotel bookings?

    Yes. In addition to deals on Buffalo to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Greenville.

  • Can I find deals for business class flights from Buffalo to Greenville?

    Yes. Cheapflights offers flight deals from Buffalo to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $63). Flying from Buffalo to Greenville in December is currently the most expensive (average of $197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Buffalo to Greenville

Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$326FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$312FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$277Average$406FlexibilityNo cancel feeOn-time63%

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