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$136+ Cheap flights from Buffalo to Greenville (BUF - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Buffalo to Greenville

Cheapest flights from Buffalo to Greenville
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:45 pm
BUF
-
GSP
1 stop4h 05m
Southwest
Tue 3/108:00 am
GSP
-
BUF
1 stop3h 40m
Southwest
Deal found 1/20$271
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:23 am
BUF
-
GSP
1 stop4h 51m
American Airlines
Sun 4/512:23 pm
GSP
-
BUF
1 stop10h 27m
American Airlines
Deal found 1/21$308
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:23 am
BUF
-
GSP
1 stop4h 51m
American Airlines
Wed 4/86:00 am
GSP
-
BUF
1 stop5h 14m
American Airlines
Deal found 1/21$331
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/612:38 pm
BUF
-
GSP
1 stop9h 38m
American Airlines
Tue 2/106:05 am
GSP
-
BUF
1 stop9h 12m
American Airlines
Deal found 1/20$356
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:54 am
BUF
-
GSP
1 stop11h 36m
American Airlines
Thu 8/66:00 am
GSP
-
BUF
1 stop5h 04m
American Airlines
Deal found 1/21$357
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:50 pm
BUF
-
GSP
1 stop6h 10m
Delta
Wed 8/56:05 pm
GSP
-
BUF
1 stop4h 55m
Delta
Deal found 1/21$367
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:50 pm
BUF
-
GSP
1 stop6h 10m
Delta
Tue 8/46:45 am
GSP
-
BUF
1 stop4h 30m
Delta
Deal found 1/21$368
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:50 pm
BUF
-
GSP
1 stop6h 10m
Delta
Wed 8/57:15 am
GSP
-
BUF
1 stop4h 25m
Delta
Deal found 1/21$371

Find flight deals from Buffalo to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$271
(Southwest)

One-way from

$136
(American Airlines)

Popular in

September

Cheapest in

June

Average price

$328
Provider with most accurate pricing for Buffalo-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Greenville flights.
Search Deals
From Buffalo to Greenville
Search Deals
One-way flight from Buffalo to Greenville
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.

Fly from

Buffalo

Fly to

Greenville

Route

Depart

Return

Price

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 2/24

3:45 pm-7:50 pm

1 stop4h 05m

Greenville

Tue 3/10

8:00 am-11:40 am

1 stop3h 40m

$271

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/31

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Sun 4/5

12:23 pm-10:50 pm

1 stop10h 27m

$308

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Wed 4/8

6:00 am-11:14 am

1 stop5h 14m

$331

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 2/6

4:01 pm-11:26 pm

2 stops7h 25m

Greenville

Tue 2/10

7:16 am-12:08 pm

1 stop4h 52m

$364

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/31

4:40 pm-8:30 pm

1 stop3h 50m

Greenville

Sun 4/5

8:00 am-3:40 pm

2 stops7h 40m

$374

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 2/13

7:00 am-12:14 pm

1 stop5h 14m

Greenville

Tue 2/17

6:53 pm-10:50 pm

1 stop3h 57m

$381

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Wed 2/4

6:20 pm-11:48 pm

1 stop5h 28m

Greenville

Sun 2/8

6:35 am-2:14 pm

2 stops7h 39m

$452

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/10

5:29 pm-10:05 pm

1 stop4h 36m

$136

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 1/29

1:39 pm-8:07 pm

2 stops30h 28m

$142

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 2/26

1:39 pm-5:59 pm

2 stops28h 20m

$144

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 14 results
1
2

Compare providers for flights from Buffalo to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Greenville

What is the cheapest month to book a flight from Buffalo to Greenville?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $105). Flying from Buffalo to Greenville in November is currently the most expensive (average of $208). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 21, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,089 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,174 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Greenville?

    Southwest and American Airlines can get you from Buffalo to Greenville in just under 4h 05m. Your travel time can differ by up to 46m. The distance between Buffalo and Greenville is about 586 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to Greenville round-trip?

    Our cheapest airline available from Buffalo to Greenville is American Airlines. Our recent data shows that you can find tickets from as low as $198 on this airline. Additional options worth looking into are Delta and Southwest, starting at $276 and $277 round-trip. You may be able to fly from Buffalo to Greenville for 46% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Greenville that include hotel bookings?

    Yes. In addition to deals on Buffalo to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Greenville.

  • Can I find deals for business class flights from Buffalo to Greenville?

    Yes. Cheapflights offers flight deals from Buffalo to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $105). Flying from Buffalo to Greenville in November is currently the most expensive (average of $208). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Buffalo to Greenville

Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$335FlexibilityNo cancel feeOn-time71%
DeltaCheapest$276Average$336FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$277Average$406FlexibilityNo cancel feeOn-time63%

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