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$136+ Cheap flights from Buffalo to Greenville (BUF - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Apr 7 — Apr 141
Tue 4/7
Tue 4/14
1 adult, Economy
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Cheap flight deals from Buffalo to Greenville

Cheapest flights from Buffalo to Greenville
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2026.

This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:50 pm
BUF
-
GSP
1 stop5h 08m
United Airlines
Tue 5/196:27 pm
GSP
-
BUF
1 stop5h 06m
United Airlines
Deal found 3/3$271
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:25 am
BUF
-
GSP
1 stop6h 55m
Southwest
Tue 5/1912:50 pm
GSP
-
BUF
2 stops9h 25m
Southwest
Deal found 3/3$276
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:55 am
BUF
-
GSP
1 stop4h 20m
American Airlines
Sat 4/46:00 am
GSP
-
BUF
1 stop4h 58m
American Airlines
Deal found 3/4$286
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:23 am
BUF
-
GSP
1 stop4h 51m
American Airlines
Tue 4/76:00 am
GSP
-
BUF
1 stop5h 28m
American Airlines
Deal found 3/3$290
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:29 am
BUF
-
GSP
1 stop4h 51m
American Airlines
Wed 4/87:48 pm
GSP
-
BUF
1 stop4h 11m
American Airlines
Deal found 3/4$291
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:12 pm
BUF
-
GSP
1 stop5h 07m
American Airlines
Tue 4/146:28 pm
GSP
-
BUF
1 stop5h 21m
American Airlines
Deal found 3/6$301
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:00 am
BUF
-
GSP
1 stop4h 54m
United Airlines
Tue 4/1412:34 pm
GSP
-
BUF
2 stops10h 59m
United Airlines
Deal found 3/6$306
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2212:45 pm
BUF
-
GSP
2 stops30h 53m
Multiple Airlines
Fri 3/278:18 pm
GSP
-
BUF
1 stop14h 31m
Multiple Airlines
Deal found 3/5$325
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
BUF
-
GSP
1 stop5h 14m
United Airlines
Fri 4/1010:33 am
GSP
-
BUF
1 stop3h 44m
United Airlines
Deal found 3/5$329
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:02 am
BUF
-
GSP
1 stop4h 15m
American Airlines
Thu 6/116:14 am
GSP
-
BUF
1 stop7h 12m
American Airlines
Deal found 3/6$334

Find flight deals from Buffalo to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(United Airlines)

One-way from

$136
(Southwest)

Popular in

September

Cheapest in

June

Average price

$386
Provider with most accurate pricing for Buffalo-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Greenville flights.
Search Deals
From Buffalo to Greenville
Search Deals
One-way flight from Buffalo to Greenville
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 5/5

5:50 pm-10:58 pm

1 stop5h 08m

Greenville

Tue 5/19

6:27 pm-11:33 pm

1 stop5h 06m

$271

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 5/5

9:25 am-4:20 pm

1 stop6h 55m

Greenville

Tue 5/19

12:50 pm-10:15 pm

2 stops9h 25m

$276

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 5/2

7:00 am-2:10 pm

1 stop7h 10m

Greenville

Tue 5/5

6:27 pm-11:33 pm

1 stop5h 06m

$356

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/31

4:40 pm-8:30 pm

1 stop3h 50m

Greenville

Tue 4/7

6:45 am-2:35 pm

2 stops7h 50m

$389

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 6/26

5:55 pm-9:35 pm

1 stop3h 40m

Greenville

Mon 6/29

12:55 pm-10:35 pm

2 stops9h 40m

$392
Cheapest one-way

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 4/21

9:25 am-4:20 pm

1 stop6h 55m

$136

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/23

12:35 pm-7:38 pm

2 stops31h 03m

$155

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 4/17

10:52 am-7:38 pm

1 stop8h 46m

$183

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sun 5/17

8:55 am-1:10 pm

1 stop4h 15m

$184

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 4/24

4:00 pm-8:55 pm

1 stop4h 55m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/3

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Buffalo to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Greenville

What is the cheapest month to book a flight from Buffalo to Greenville?

Currently, July is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $118). Flying from Buffalo to Greenville in January is currently the most expensive (average of $214). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated March 8, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,315 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..
Southwest
8.0
Very good
4,315 reviews
Southwest
8.0
Very good
4,315 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..
Delta
7.9
Good
8,269 reviews
Southwest
8.0
Very good
4,315 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..
American Airlines
7.1
Good
11,397 reviews
Southwest
8.0
Very good
4,315 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Greenville?

    United Airlines and Southwest can get you from Buffalo to Greenville in just under 5h 08m. Your travel time can differ by up to 1h 47m. The distance between Buffalo and Greenville is about 586 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to Greenville round-trip?

    Our cheapest airline available from Buffalo to Greenville is American Airlines. Our recent data shows that you can find tickets from as low as $257 on this airline. Additional options worth looking into are Southwest and Delta, starting at $277 and $296 round-trip. You may be able to fly from Buffalo to Greenville for 32% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Buffalo to Greenville one-way?

    $102 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $108 and $128, respectively.

  • Can I find deals for flights from Buffalo to Greenville that include hotel bookings?

    Yes. In addition to deals on Buffalo to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Greenville.

  • Can I find deals for business class flights from Buffalo to Greenville?

    Yes. Cheapflights offers flight deals from Buffalo to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Greenville?

    Currently, July is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $118). Flying from Buffalo to Greenville in January is currently the most expensive (average of $214). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Buffalo to Greenville

Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$257Average$335FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$277Average$386FlexibilityNo cancel feeOn-time63%
DeltaCheapest$296Average$396FlexibilityNo cancel feeOn-timeN/A

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