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$136+ Cheap flights from Buffalo to Greenville (BUF - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Feb 13 — Feb 201
Fri 2/13
Fri 2/20
1 adult, Economy
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Cheap flight deals from Buffalo to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 14, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$271
(Delta)

One-way from

$136
(American Airlines)

Popular in

September

Cheapest in

June

Average price

$328
Provider with most accurate pricing for Buffalo-Greenville flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Greenville flights.
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From Buffalo to Greenville
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One-way flight from Buffalo to Greenville
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Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Buffalo to Greenville

Cheapest flights from Buffalo to Greenville
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 14, 2026.

This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/312:25 pm
BUF
-
GSP
1 stop5h 39m
Delta
Tue 2/106:50 am
GSP
-
BUF
1 stop4h 29m
Delta
Deal found 1/12$271
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/34:01 pm
BUF
-
GSP
2 stops7h 35m
American Airlines
Tue 2/107:03 am
GSP
-
BUF
1 stop5h 05m
American Airlines
Deal found 1/12$276
This Southwest deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/35:50 am
BUF
-
GSP
2 stops11h 45m
Southwest
Tue 2/1011:15 am
GSP
-
BUF
2 stops10h 40m
Southwest
Deal found 1/12$295
This Southwest deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:10 pm
BUF
-
GSP
2 stops8h 30m
Southwest
Tue 5/512:50 pm
GSP
-
BUF
2 stops7h 35m
Southwest
Deal found 1/12$298
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:00 am
BUF
-
GSP
1 stop12h 27m
American Airlines
Tue 2/106:00 am
GSP
-
BUF
1 stop6h 08m
American Airlines
Deal found 1/12$316
This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:30 pm
BUF
-
GSP
1 stop4h 26m
Delta
Tue 4/215:40 pm
GSP
-
BUF
1 stop6h 17m
Delta
Deal found 1/12$329
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:23 am
BUF
-
GSP
1 stop4h 51m
American Airlines
Wed 4/86:00 am
GSP
-
BUF
1 stop5h 14m
American Airlines
Deal found 1/13$337
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/124:04 pm
BUF
-
GSP
1 stop6h 04m
American Airlines
Fri 2/206:53 pm
GSP
-
BUF
1 stop3h 57m
American Airlines
Deal found 1/13$355
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:54 am
BUF
-
GSP
1 stop11h 36m
American Airlines
Mon 7/277:39 pm
GSP
-
BUF
1 stop4h 12m
American Airlines
Deal found 1/12$356

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.

Fly from

Buffalo

Fly to

Greenville

Route

Depart

Return

Price

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 2/3

5:27 pm-10:16 pm

1 stop4h 49m

Greenville

Tue 2/10

6:00 am-12:08 pm

1 stop6h 08m

$271

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 4/28

9:45 am-1:10 pm

1 stop3h 25m

Greenville

Tue 5/5

8:20 am-2:35 pm

1 stop6h 15m

$271

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 2/3

12:25 pm-6:04 pm

1 stop5h 39m

Greenville

Tue 2/10

6:50 am-11:19 am

1 stop4h 29m

$271

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sun 4/19

7:30 pm-11:56 pm

1 stop4h 26m

Greenville

Tue 4/21

5:40 pm-11:57 pm

1 stop6h 17m

$329

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Wed 4/8

6:00 am-11:14 am

1 stop5h 14m

$337

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 2/6

4:01 pm-11:26 pm

2 stops7h 25m

Greenville

Tue 2/10

7:16 am-12:08 pm

1 stop4h 52m

$344

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 2/12

4:04 pm-10:08 pm

1 stop6h 04m

Greenville

Fri 2/20

6:53 pm-10:50 pm

1 stop3h 57m

$355

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/10

1:00 pm-5:29 pm

1 stop4h 29m

$136

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/10

5:29 pm-10:05 pm

1 stop4h 36m

$136

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Fri 7/3

7:00 am-11:56 am

1 stop4h 56m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 17 results
1
2

Compare providers for flights from Buffalo to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Greenville

What is the cheapest month to book a flight from Buffalo to Greenville?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $104). Flying from Buffalo to Greenville in November is currently the most expensive (average of $208). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 14, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,257 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,257 reviews
Southwest
8.0
Very good
4,257 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,040 reviews
Southwest
8.0
Very good
4,257 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,118 reviews
Southwest
8.0
Very good
4,257 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Greenville?

    American Airlines, Southwest, and Delta can get you from Buffalo to Greenville in just under 3h 25m. Your travel time can differ by up to 2h 14m. The distance between Buffalo and Greenville is about 586 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Buffalo to Greenville round-trip?

    Our cheapest airline available from Buffalo to Greenville is American Airlines. Our recent data shows that you can find tickets from as low as $198 on this airline. Additional options worth looking into are Delta and Southwest, starting at $236 and $277 round-trip. You may be able to fly from Buffalo to Greenville for 46% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Greenville that include hotel bookings?

    Yes. In addition to deals on Buffalo to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Greenville.

  • Can I find deals for business class flights from Buffalo to Greenville?

    Yes. Cheapflights offers flight deals from Buffalo to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $104). Flying from Buffalo to Greenville in November is currently the most expensive (average of $208). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Buffalo to Greenville

Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$331FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$316FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$277Average$406FlexibilityNo cancel feeOn-time63%

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