$152+ Cheap flights from Buffalo to Greenville (BUF - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Jul 23 — Jul 301
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Buffalo to GreenvilleExplore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:57 pm
BUF
- GSP
1 stop11h 38m
Multiple Airlines
Sun 8/28:25 am
GSP
- BUF
2 stops29h 28m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:35 pm
BUF
- GSP
1 stop4h 16m
American Airlines
Tue 8/412:56 pm
GSP
- BUF
1 stop3h 59m
American Airlines
Deal found 6/22![American Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:01 pm
BUF
- GSP
1 stop5h 47m
Delta
Sat 7/44:05 pm
GSP
- BUF
1 stop5h 22m
Delta
Deal found 6/19![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:00 pm
BUF
- GSP
2 stops8h 34m
United Airlines
Tue 8/47:40 pm
GSP
- BUF
1 stop4h 19m
United Airlines
Deal found 6/22![United Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:16 pm
BUF
- GSP
2 stops24h 12m
Multiple Airlines
Mon 9/288:32 pm
GSP
- BUF
1 stop21h 02m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:59 pm
BUF
- GSP
1 stop3h 51m
American Airlines
Thu 8/136:28 am
GSP
- BUF
1 stop4h 08m
American Airlines
Deal found 6/21![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:15 am
BUF
- GSP
1 stop3h 40m
United Airlines
Tue 8/42:55 pm
GSP
- BUF
2 stops8h 11m
United Airlines
Deal found 6/21![United Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
BUF
- GSP
1 stop4h 04m
American Airlines
Mon 10/57:41 pm
GSP
- BUF
1 stop3h 45m
American Airlines
Deal found 6/22![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:02 pm
BUF
- GSP
1 stop9h 26m
Multiple Airlines
Thu 8/133:53 pm
GSP
- BUF
2 stops22h 00m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:16 pm
BUF
- GSP
2 stops18h 35m
Multiple Airlines
Mon 10/58:32 pm
GSP
- BUF
1 stop21h 02m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
BUF
- GSP
1 stop6h 26m
American Airlines
Sat 7/252:35 pm
GSP
- BUF
2 stops6h 49m
American Airlines
Deal found 6/19![American Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
BUF
- GSP
1 stop6h 26m
American Airlines
Sun 8/28:00 am
GSP
- BUF
1 stop6h 19m
American Airlines
Deal found 6/18![American Airlines logo]()
$345
Best flights from Buffalo to GreenvilleDiscover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
Discover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:57 pm
BUF
- GSP
1 stop11h 38m
Multiple Airlines
Sun 8/28:25 am
GSP
- BUF
2 stops29h 28m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$270
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am
BUF
- GSP
1 stop4h 58m
Delta
Mon 10/127:55 pm
GSP
- BUF
1 stop4h 00m
Delta
Deal found 6/18![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:50 am
BUF
- GSP
1 stop8h 10m
Southwest
Wed 8/127:00 am
GSP
- BUF
2 stops7h 20m
Southwest
Deal found 6/21![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:30 am
BUF
- GSP
1 stop6h 32m
United Airlines
Wed 9/22:18 pm
GSP
- BUF
1 stop6h 49m
United Airlines
Deal found 6/22![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1711:00 am
BUF
- GSP
2 stops7h 15m
Southwest
Wed 7/221:50 pm
GSP
- BUF
1 stop8h 55m
Southwest
Deal found 6/20![Southwest logo]()
$376
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:05 am
BUF
- GSP
2 stops7h 15m
Southwest
Sun 11/18:15 am
GSP
- BUF
1 stop3h 45m
Southwest
Deal found 6/22![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:50 pm
BUF
- GSP
2 stops9h 15m
Southwest
Sun 8/26:50 am
GSP
- BUF
2 stops7h 35m
Southwest
Deal found 6/18![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:20 am
BUF
- GSP
2 stops10h 00m
Southwest
Mon 10/122:00 pm
GSP
- BUF
1 stop4h 25m
Southwest
Deal found 6/18![Southwest logo]()
$418
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:50 pm
BUF
- GSP
2 stops8h 05m
Southwest
Thu 7/2312:55 pm
GSP
- BUF
2 stops11h 20m
Southwest
Deal found 6/18![Southwest logo]()
$423
Last-minute flights from Buffalo to GreenvilleDiscover last-minute flight deals from Buffalo to Greenville. Data last updated June 23, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Greenville. Data last updated June 23, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:01 pm
BUF
- GSP
1 stop5h 47m
Delta
Sat 7/44:05 pm
GSP
- BUF
1 stop5h 22m
Delta
Deal found 6/19![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:02 am
BUF
- GSP
1 stop4h 15m
American Airlines
Sat 7/46:35 am
GSP
- BUF
2 stops9h 44m
American Airlines
Deal found 6/19![American Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:32 pm
BUF
- GSP
1 stop4h 20m
American Airlines
Fri 7/106:18 pm
GSP
- BUF
1 stop4h 33m
American Airlines
Deal found 6/18![American Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:35 pm
BUF
- GSP
1 stop4h 16m
American Airlines
Tue 8/412:56 pm
GSP
- BUF
1 stop3h 59m
American Airlines
Deal found 6/22![American Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:00 pm
BUF
- GSP
2 stops8h 34m
United Airlines
Tue 8/47:40 pm
GSP
- BUF
1 stop4h 19m
United Airlines
Deal found 6/22![United Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:00 am
BUF
- GSP
2 stops8h 00m
Southwest
Tue 8/47:00 am
GSP
- BUF
2 stops7h 20m
Southwest
Deal found 6/22![Southwest logo]()
$375
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
BUF
- GSP
2 stops8h 20m
United Airlines
Tue 7/217:40 pm
GSP
- BUF
1 stop4h 19m
United Airlines
Deal found 6/20![United Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:00 am
BUF
- GSP
1 stop4h 15m
American Airlines
Wed 7/226:00 am
GSP
- BUF
1 stop4h 40m
American Airlines
Deal found 6/20![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1711:00 am
BUF
- GSP
2 stops7h 15m
Southwest
Wed 7/221:50 pm
GSP
- BUF
1 stop8h 55m
Southwest
Deal found 6/18![Southwest logo]()
$376
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
BUF
- GSP
1 stop6h 26m
American Airlines
Sat 7/252:35 pm
GSP
- BUF
2 stops6h 49m
American Airlines
Deal found 6/19![American Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:57 pm
BUF
- GSP
1 stop11h 38m
Multiple Airlines
Sun 8/28:25 am
GSP
- BUF
2 stops29h 28m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
BUF
- GSP
1 stop6h 26m
American Airlines
Sun 8/28:00 am
GSP
- BUF
1 stop6h 19m
American Airlines
Deal found 6/18![American Airlines logo]()
$345
One-way flights from Buffalo to GreenvilleSearch for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
Search for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
BUF
- GSP
1 stop4h 15m
American Airlines
Deal found 6/18![American Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:48 pm
BUF
- GSP
2 stops17h 09m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:48 pm
BUF
- GSP
2 stops41h 09m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$162
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:49 pm
BUF
- GSP
1 stop6h 01m
American Airlines
Deal found 6/21![American Airlines logo]()
$194
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:24 am
BUF
- GSP
1 stop6h 25m
American Airlines
Deal found 6/18![American Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/149:09 pm
BUF
- GSP
3 stops34h 48m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$210
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:25 am
BUF
- GSP
2 stops9h 55m
Southwest
Deal found 6/18![Southwest logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:22 pm
BUF
- GSP
2 stops26h 11m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:44 am
BUF
- GSP
1 stop7h 06m
American Airlines
Deal found 6/21![American Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:00 am
BUF
- GSP
2 stops8h 00m
Southwest
Deal found 6/21![Southwest logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:09 pm
BUF
- GSP
3 stops34h 48m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$256
Find flight deals from Buffalo to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $270 (Kiwi.com) |
One-way from | $152 (American Airlines) |
Popular in | September |
Cheapest in | January |
Average price | $386 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Wed 7/29
7:57 pm-7:35 am
1 stop11h 38m
Greenville
Sun 8/2
8:25 am-1:53 pm
2 stops29h 28m
$270
Quickest round-trip
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Sat 10/10
6:00 am-10:58 am
1 stop4h 58m
Greenville
Mon 10/12
7:55 pm-11:55 pm
1 stop4h 00m
$325
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Sat 8/8
10:50 am-7:00 pm
1 stop8h 10m
Greenville
Wed 8/12
7:00 am-2:20 pm
2 stops7h 20m
$354
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Fri 7/17
11:00 am-6:15 pm
2 stops7h 15m
Greenville
Wed 7/22
1:50 pm-10:45 pm
1 stop8h 55m
$376
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Tue 9/1
10:30 am-5:02 pm
1 stop6h 32m
Greenville
Wed 9/2
2:18 pm-9:07 pm
1 stop6h 49m
$383
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Thu 10/22
5:05 am-12:20 pm
2 stops7h 15m
Greenville
Sun 11/1
8:15 am-12:00 pm
1 stop3h 45m
$392
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Wed 7/29
12:50 pm-10:05 pm
2 stops9h 15m
Greenville
Sun 8/2
6:50 am-2:25 pm
2 stops7h 35m
$417
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Sat 10/10
7:20 am-5:20 pm
2 stops10h 00m
Greenville
Mon 10/12
2:00 pm-6:25 pm
1 stop4h 25m
$418
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Thu 7/16
2:50 pm-10:55 pm
2 stops8h 05m
Greenville
Thu 7/23
12:55 pm-12:15 am
2 stops11h 20m
$423
Cheapest one-way
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Fri 8/14
2:48 pm-7:57 am
2 stops41h 09m
$162
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
BUF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Greenville
Prices
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What is the cheapest month to book a flight from Buffalo to Greenville?
Currently, January is the cheapest month in which you can book a flight from Buffalo to Greenville (average of $328). Flying from Buffalo to Greenville in September is currently the most expensive (average of $595). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to Greenville?
What’s the top layover airport for flights from Buffalo to Greenville?
Share of 1-stop round-trip flights from Buffalo to Greenville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Washington, D.C. (DCA) – chosen by Cheapflights users on 40% of 1-stop itineraries from Buffalo to Greenville on Cheapflights.
What’s the cheapest layover airport for flights from Buffalo to Greenville?
Average round-trip fare for 1-stop flights from Buffalo to Greenville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
New York (LGA) is the most affordable 1-stop option, with an average round-trip price of $284.
What’s the fastest layover option from Buffalo to Greenville?
Shortest average travel time for 1-stop one-way flights from Buffalo to Greenville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Washington, D.C. (DCA) have the shortest average one-way travel time for 1-stop routes: 4h 27m.
Which airport typically offers the quickest layover for flights from Buffalo to Greenville?
Average layover duration for 1-stop one-way flights from Buffalo to Greenville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (DCA) offer the fastest connection on this route, with an average layover time of 0h 51m.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated June 23, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Food
7.0
Overall
7.9
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 23, 2026.
Buffalo and Greenville flights
Browse other Buffalo and Greenville flight options. Last updated on June 23, 2026.
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Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on June 23, 2026.
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Top 3 airlines flying from Buffalo to Greenville
Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$257 | Average$348 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$294 | Average$406 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$298 | Average$414 | FlexibilityNo cancel fee | On-timeN/A |