$136+ Cheap flights from Buffalo to Greenville (BUF - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GSP
Mrz 10 — Mrz 171
1 adult, Economy
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Cheapest flights from Buffalo to GreenvilleExplore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Februar 8, 2026.
Explore the most affordable flight options available from Buffalo to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Februar 8, 2026.
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/2411:29 am
BUF
- GSP
1 stop10h 53m
American Airlines
Mi 4/16:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 2/5![American Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 4/56:00 am
BUF
- GSP
1 stop5h 05m
Delta
Mi 4/87:30 am
GSP
- BUF
1 stop4h 14m
Delta
Deal found 2/6![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/27:23 am
BUF
- GSP
1 stop4h 51m
American Airlines
Mi 4/86:00 am
GSP
- BUF
1 stop5h 14m
American Airlines
Deal found 2/5![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/1910:23 am
BUF
- GSP
1 stop7h 18m
Delta
Mo 3/306:14 pm
GSP
- BUF
1 stop4h 41m
Delta
Deal found 2/6![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/197:23 am
BUF
- GSP
1 stop4h 51m
American Airlines
Mo 3/307:37 pm
GSP
- BUF
1 stop3h 54m
American Airlines
Deal found 2/6![American Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/2911:03 am
BUF
- GSP
1 stop11h 35m
American Airlines
Sa 5/307:00 am
GSP
- BUF
1 stop9h 17m
American Airlines
Deal found 2/6![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/127:23 am
BUF
- GSP
1 stop10h 50m
American Airlines
So 3/156:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 2/6![American Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 3/147:51 pm
BUF
- GSP
1 stop4h 03m
American Airlines
Mo 3/166:53 pm
GSP
- BUF
1 stop3h 57m
American Airlines
Deal found 2/8![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 2/286:25 pm
BUF
- GSP
1 stop5h 34m
United Airlines
Di 3/312:05 pm
GSP
- BUF
1 stop5h 45m
United Airlines
Deal found 2/7![United Airlines logo]()
$367
Best flights from Buffalo to GreenvilleDiscover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Februar 8, 2026.
Discover carefully curated flight deals from Buffalo to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Februar 8, 2026.
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 4/55:30 am
BUF
- GSP
1 stop5h 14m
American Airlines
Mi 4/812:35 pm
GSP
- BUF
1 stop4h 07m
American Airlines
Deal found 2/6![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/1910:23 am
BUF
- GSP
1 stop7h 18m
Delta
Mo 3/306:14 pm
GSP
- BUF
1 stop4h 41m
Delta
Deal found 2/6![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/245:29 pm
BUF
- GSP
2 stops5h 43m
American Airlines
Mi 4/17:07 am
GSP
- BUF
1 stop5h 07m
American Airlines
Deal found 2/5![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/27:23 am
BUF
- GSP
1 stop4h 51m
American Airlines
Mi 4/86:00 am
GSP
- BUF
1 stop5h 14m
American Airlines
Deal found 2/5![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/67:28 pm
BUF
- GSP
1 stop4h 29m
American Airlines
So 5/106:52 am
GSP
- BUF
1 stop4h 22m
American Airlines
Deal found 2/5![American Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/197:23 am
BUF
- GSP
1 stop4h 51m
American Airlines
Mo 3/307:37 pm
GSP
- BUF
1 stop3h 54m
American Airlines
Deal found 2/6![American Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/127:23 am
BUF
- GSP
1 stop10h 50m
American Airlines
So 3/156:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 2/6![American Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 3/147:51 pm
BUF
- GSP
1 stop4h 03m
American Airlines
Mo 3/166:53 pm
GSP
- BUF
1 stop3h 57m
American Airlines
Deal found 2/8![American Airlines logo]()
$357
Last-minute flights from Buffalo to GreenvilleDiscover last-minute flight deals from Buffalo to Greenville. Data last updated Februar 8, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Greenville. Data last updated Februar 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 2/2112:17 pm
BUF
- GSP
1 stop7h 31m
American Airlines
Mi 2/257:20 am
GSP
- BUF
1 stop8h 05m
American Airlines
Deal found 2/6![American Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 2/286:25 pm
BUF
- GSP
1 stop5h 34m
United Airlines
Di 3/312:05 pm
GSP
- BUF
1 stop5h 45m
United Airlines
Deal found 2/7![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/127:23 am
BUF
- GSP
1 stop10h 50m
American Airlines
So 3/156:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 2/6![American Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 3/147:51 pm
BUF
- GSP
1 stop4h 03m
American Airlines
Mo 3/166:53 pm
GSP
- BUF
1 stop3h 57m
American Airlines
Deal found 2/8![American Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 3/157:21 pm
BUF
- GSP
1 stop24h 17m
Multiple Airlines
So 3/229:46 pm
GSP
- BUF
2 stops13h 18m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$420
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/1910:23 am
BUF
- GSP
1 stop7h 18m
Delta
Mo 3/306:14 pm
GSP
- BUF
1 stop4h 41m
Delta
Deal found 2/6![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/197:23 am
BUF
- GSP
1 stop4h 51m
American Airlines
Mo 3/307:37 pm
GSP
- BUF
1 stop3h 54m
American Airlines
Deal found 2/6![American Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/2411:29 am
BUF
- GSP
1 stop10h 53m
American Airlines
Mi 4/16:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Deal found 2/5![American Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/241:20 pm
BUF
- GSP
2 stops9h 20m
Southwest
Mi 4/112:35 pm
GSP
- BUF
2 stops10h 10m
Southwest
Deal found 2/5![Southwest logo]()
$397
One-way flights from Buffalo to GreenvilleSearch for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated Februar 8, 2026.
Search for one-way flight options from Buffalo to Greenville. Find affordable one-way fares based on user searches. Data last updated Februar 8, 2026.
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/155:12 pm
BUF
- GSP
1 stop5h 07m
American Airlines
Deal found 2/5![American Airlines logo]()
$136
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/107:38 pm
BUF
- GSP
1 stop4h 16m
Delta
Deal found 2/7![Delta logo]()
$149
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/127:23 am
BUF
- GSP
1 stop4h 51m
American Airlines
Deal found 2/7![American Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/151:08 pm
BUF
- GSP
2 stops20h 40m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$172
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/151:10 pm
BUF
- GSP
2 stops8h 30m
Southwest
Deal found 2/4![Southwest logo]()
$176
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 3/86:02 am
BUF
- GSP
1 stop4h 56m
Delta
Deal found 2/5![Delta logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/1212:50 pm
BUF
- GSP
2 stops30h 48m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$190
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/106:00 am
BUF
- GSP
2 stops10h 51m
United Airlines
Deal found 2/8![United Airlines logo]()
$192
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 3/86:19 am
BUF
- GSP
1 stop3h 56m
American Airlines
Deal found 2/8![American Airlines logo]()
$194
Find flight deals from Buffalo to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated Februar 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $308 (American Airlines) |
One-way from | $136 (American Airlines) |
Popular in | September |
Cheapest in | April |
Average price | $367 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Februar 8, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.
Fly from
Buffalo
Fly to
Greenville
Route
Depart
Return
Price
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
So 4/5
5:30 am-10:44 am
1 stop5h 14m
Greenville
Mi 4/8
12:35 pm-4:42 pm
1 stop4h 07m
$319
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Di 3/24
5:29 pm-11:12 pm
2 stops5h 43m
Greenville
Mi 4/1
7:07 am-12:14 pm
1 stop5h 07m
$324
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Do 4/2
7:23 am-12:14 pm
1 stop4h 51m
Greenville
Mi 4/8
6:00 am-11:14 am
1 stop5h 14m
$333
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Do 3/19
10:23 am-5:41 pm
1 stop7h 18m
Greenville
Mo 3/30
6:14 pm-10:55 pm
1 stop4h 41m
$335
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Mi 5/6
7:28 pm-11:57 pm
1 stop4h 29m
Greenville
So 5/10
6:52 am-11:14 am
1 stop4h 22m
$338
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Do 3/19
7:23 am-12:14 pm
1 stop4h 51m
Greenville
Mo 3/30
7:37 pm-11:31 pm
1 stop3h 54m
$350
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Do 3/12
7:23 am-6:13 pm
1 stop10h 50m
Greenville
So 3/15
6:00 am-10:58 am
1 stop4h 58m
$356
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Sa 3/14
7:51 pm-11:54 pm
1 stop4h 03m
Greenville
Mo 3/16
6:53 pm-10:50 pm
1 stop3h 57m
$357
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Mi 4/15
5:12 pm-10:19 pm
1 stop5h 07m
$136
BuffaloGreenville
BUF - GSP
BUFGSP
Buffalo
Di 3/10
7:38 pm-11:54 pm
1 stop4h 16m
$149
Showing 1-10 of 18 results
Compare providers for flights from Buffalo to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Greenville in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Buffalo with our price prediction graph.
BUF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Greenville
Prices
More
What’s the top layover airport for flights from Buffalo to Greenville?
Share of 1-stop round-trip flights from Buffalo to Greenville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Washington, D.C. (DCA) – chosen by Cheapflights users on 40% of 1-stop itineraries from Buffalo to Greenville on Cheapflights.
What’s the cheapest layover airport for flights from Buffalo to Greenville?
Average round-trip fare for 1-stop flights from Buffalo to Greenville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
New York (LGA) is the most affordable 1-stop option, with an average round-trip price of $284.
What’s the fastest layover option from Buffalo to Greenville?
Shortest average travel time for 1-stop one-way flights from Buffalo to Greenville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Washington, D.C. (DCA) have the shortest average one-way travel time for 1-stop routes: 4h 27m.
Which airport typically offers the quickest layover for flights from Buffalo to Greenville?
Average layover duration for 1-stop one-way flights from Buffalo to Greenville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (DCA) offer the fastest connection on this route, with an average layover time of 0h 51m.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated Februar 8, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Buffalo to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsSimpsonville
Duncan
Greer
Seneca
Anderson
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Alternative routes for Buffalo to Greenville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Greenville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to Greenville by cabin class
Find flights from Buffalo to Greenville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on Februar 8, 2026.
Buffalo and Greenville flights
Browse other Buffalo and Greenville flight options. Last updated on Februar 8, 2026.
Other flights from Buffalo
Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on Februar 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Buffalo to Greenville
Discover the top 3 airlines that operate flights from Buffalo to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Februar 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$335 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$336 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$277 | Average$386 | FlexibilityNo cancel fee | On-time63% |