HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$179+ Cheap flights from Syracuse to Greenville (SYR - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — GSP
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Syracuse to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Syracuse Hancock Intl to Greenville are usually found in May or August, booked 22 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Syracuse to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$231
(American Airlines)

One-way from

$179
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$300
From Syracuse Hancock Intl to Greenville
Search Deals
One-way flight from Syracuse Hancock Intl to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Syracuse to Greenville

Cheapest flights from Syracuse to Greenville
Explore the most affordable flight options available from Syracuse to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2511:57 amSYR - GSP
1 stop6h 35mAmerican Airlines
Tue 10/286:00 amGSP - SYR
1 stop6h 28mAmerican Airlines
Deal found 9/14$231
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/11:00 pmSYR - GSP
1 stop4h 41mDelta
Mon 11/36:00 amGSP - SYR
1 stop5h 37mDelta
Deal found 9/16$240
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:00 amSYR - GSP
1 stop4h 44mDelta
Wed 10/227:30 amGSP - SYR
1 stop4h 23mDelta
Deal found 9/14$245
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:39 pmSYR - GSP
1 stop5h 16mDelta
Thu 10/167:41 pmGSP - SYR
1 stop4h 39mDelta
Deal found 9/13$249
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:00 amSYR - GSP
2 stops8h 11mUnited Airlines
Wed 10/226:05 pmGSP - SYR
1 stop5h 10mUnited Airlines
Deal found 9/14$250
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:10 pmSYR - GSP
1 stop5h 31mDelta
Sat 10/115:16 pmGSP - SYR
1 stop7h 04mDelta
Deal found 9/15$254
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/412:01 pmSYR - GSP
2 stops7h 12mAmerican Airlines
Sat 10/185:00 amGSP - SYR
2 stops6h 27mAmerican Airlines
Deal found 9/15$255
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/111:03 amSYR - GSP
2 stops8h 03mUnited Airlines
Sat 10/113:55 pmGSP - SYR
1 stop5h 33mUnited Airlines
Deal found 9/15$259
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/135:30 amSYR - GSP
1 stop5h 15mAmerican Airlines
Sat 10/186:11 amGSP - SYR
1 stop5h 53mAmerican Airlines
Deal found 9/15$265
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1612:16 pmSYR - GSP
2 stops31h 07mMultiple Airlines
Mon 10/208:51 pmGSP - SYR
1 stop13h 26mMultiple Airlines
Deal found 9/14$266

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Syracuse to Greenville that are best for you.

Fly from

Syracuse

Fly to

Greenville

Route

Depart

Return

Price

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Sat 11/1

1:38 pm-7:20 pm

1 stop5h 42m

Greenville

Tue 11/4

7:38 am-11:43 am

1 stop4h 05m

$231

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Sat 11/1

6:00 am-10:48 am

1 stop4h 48m

Greenville

Tue 11/4

5:30 am-11:02 am

1 stop5h 32m

$231

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Sat 11/1

1:38 pm-5:56 pm

1 stop4h 18m

Greenville

Mon 11/3

6:00 am-11:40 am

1 stop5h 40m

$240

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Sat 11/1

1:00 pm-5:41 pm

1 stop4h 41m

Greenville

Mon 11/3

6:00 am-11:37 am

1 stop5h 37m

$240

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Sat 11/1

4:00 pm-8:38 pm

1 stop4h 38m

Greenville

Mon 11/17

7:38 pm-11:41 pm

1 stop4h 03m

$240

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Fri 11/7

6:45 pm-11:55 pm

1 stop5h 10m

Greenville

Sat 11/8

7:30 am-11:53 am

1 stop4h 23m

$240

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Sun 10/12

6:15 am-11:46 am

1 stop5h 31m

Greenville

Sat 10/18

3:55 pm-9:28 pm

1 stop5h 33m

$245

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Fri 10/3

6:44 pm-11:52 pm

1 stop5h 08m

Greenville

Sat 10/25

5:16 pm-12:20 am

1 stop7h 04m

$245

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Sat 10/4

2:05 pm-7:22 pm

1 stop5h 17m

Greenville

Sat 10/25

5:16 pm-12:20 am

1 stop7h 04m

$245

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Fri 10/3

6:44 pm-11:52 pm

1 stop5h 08m

Greenville

Wed 10/22

6:44 pm-11:04 pm

1 stop4h 20m

$245

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 19 results
1
2

Best time to book a flight from Syracuse to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Greenville

How far ahead should I book a flight from Syracuse to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to Greenville. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Syracuse to Greenville, you should look to book at least 22 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Syracuse to Greenville?

Currently, August is the cheapest month in which you can book a flight from Syracuse to Greenville (average of $321). Flying from Syracuse to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to GSP?

Find hourly flight availability from Syracuse to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Syracuse to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 33% versus a flight at noon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 16, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Overall

8.0

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Greenville?

    For as low as $231, American Airlines can have you in Greenville from Syracuse in 4h 48m. The distance from Syracuse to Greenville is about 655 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Syracuse to Greenville round-trip?

    Currently priced at $198, American Airlines will fly you from Syracuse to Greenville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $230 and $248, respectively. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Syracuse to Greenville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Greenville.

  • Can I find deals for business class flights from Syracuse to Greenville?

    Yes. Cheapflights offers flight deals from Syracuse to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Syracuse to Greenville (average of $321). Flying from Syracuse to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Syracuse to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
Newark to Charlotte flights
John F Kennedy Intl to Charleston flights
Newark to Charleston flights
LaGuardia to Charlotte flights
John F Kennedy Intl to Savannah flights
LaGuardia to Charleston flights
Newark to Savannah flights
John F Kennedy Intl to Myrtle Beach flights
Newark to Myrtle Beach flights
LaGuardia to Savannah flights
LaGuardia to Myrtle Beach flights
John F Kennedy Intl to Greenville flights
Buffalo to Charlotte flights
LaGuardia to Greenville flights
Newark to Greenville flights
Rochester to Charlotte flights
LaGuardia to Columbia flights
White Plains to Myrtle Beach flights
John F Kennedy Intl to Columbia flights
Syracuse to Charlotte flights
Newark to Columbia flights
Stewart to Myrtle Beach flights
White Plains to Charleston flights
Islip to Charleston flights
Islip to Charlotte flights
Stewart to Charleston flights
White Plains to Savannah flights
LaGuardia to Hilton Head Island flights
Albany to Charlotte flights
White Plains to Charlotte flights
John F Kennedy Intl to Hilton Head Island flights
Rochester to Greenville flights
Newark to Hilton Head Island flights
John F Kennedy Intl to Augusta flights
Rochester to Charleston flights
Islip to Myrtle Beach flights
Newark to Augusta flights
Syracuse to Savannah flights
Rochester to Savannah flights
Albany to Greenville flights
Albany to Charleston flights
Rochester to Myrtle Beach flights
Buffalo to Greenville flights
Buffalo to Savannah flights
Buffalo to Myrtle Beach flights
LaGuardia to Augusta flights
Buffalo to Charleston flights
Stewart to Savannah flights

Top 3 airlines flying from Syracuse to Greenville

Discover the top 3 airlines that operate flights from Syracuse to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$309FlexibilityNo cancel feeOn-time71%
DeltaCheapest$230Average$287FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$388FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.