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$176+ Cheap flights from Santa Ana to Greenville (SNA - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — GSP
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Santa Ana to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$353
(Mytrip)

One-way from

$176
(American Airlines)

Popular in

June

Cheapest in

August

Average price

$406
From Santa Ana J. Wayne/Orange Cnty to Greenville
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One-way flight from Santa Ana J. Wayne/Orange Cnty to Greenville
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Highest demand for flights based on searches. 9% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santa Ana to Greenville

Cheapest flights from Santa Ana to Greenville
Explore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/167:58 pmSNA - GSP
2 stops22h 18mMultiple Airlines
Mon 7/214:05 pmGSP - SNA
2 stops22h 21mMultiple Airlines
Deal found 7/2$353
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/302:47 pmSNA - GSP
1 stop6h 18mAmerican Airlines
Wed 8/67:41 amGSP - SNA
1 stop9h 04mAmerican Airlines
Deal found 7/2$354
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:55 pmSNA - GSP
2 stops12h 00mSouthwest
Sun 9/287:15 amGSP - SNA
2 stops10h 10mSouthwest
Deal found 7/1$388
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/37:05 pmSNA - GSP
2 stops11h 56mUnited Airlines
Fri 8/85:35 pmGSP - SNA
1 stop7h 42mUnited Airlines
Deal found 7/1$432
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:10 amSNA - GSP
2 stops10h 57mDelta
Sun 9/286:35 amGSP - SNA
1 stop9h 07mDelta
Deal found 7/1$539
This Alaska Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:45 amSNA - GSP
2 stops12h 02mAlaska Airlines
Mon 10/207:29 amGSP - SNA
2 stops12h 28mAlaska Airlines
Deal found 7/2$597

Cheapflights Fare Finder

Customize your flight search to find flights from Santa Ana to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Santa Ana to Greenville that are best for you.

Fly from

Santa Ana

Fly to

Greenville

Route

Depart

Return

Price

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Wed 7/16

7:58 pm-9:16 pm

2 stops22h 18m

Greenville

Mon 7/21

4:05 pm-11:26 am

2 stops22h 21m

$353

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Wed 7/30

2:47 pm-12:05 am

1 stop6h 18m

Greenville

Wed 8/6

7:41 am-1:45 pm

1 stop9h 04m

$354

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Wed 9/24

6:55 pm-9:55 am

2 stops12h 00m

Greenville

Sun 9/28

7:15 am-2:25 pm

2 stops10h 10m

$388

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sun 8/3

7:05 pm-10:01 am

2 stops11h 56m

Greenville

Fri 8/8

5:35 pm-10:17 pm

1 stop7h 42m

$432

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Wed 9/24

7:10 am-9:07 pm

2 stops10h 57m

Greenville

Sun 9/28

6:35 am-12:42 pm

1 stop9h 07m

$539

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Thu 10/16

6:45 am-9:47 pm

2 stops12h 02m

Greenville

Mon 10/20

7:29 am-4:57 pm

2 stops12h 28m

$597

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 8/5

9:14 am-7:42 pm

1 stop7h 28m

$176

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 7/29

7:58 pm-8:52 pm

3 stops21h 54m

$183

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Wed 7/16

4:10 pm-12:04 pm

3 stops16h 54m

$533

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Santa Ana to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Greenville

What is the cheapest month to book a flight from Santa Ana to Greenville?

Currently, January is the cheapest month in which you can book a flight from Santa Ana to Greenville (average of $329). Flying from Santa Ana to Greenville in March is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to GSP?

Find hourly flight availability from Santa Ana to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

When flying from Santa Ana to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 2% versus a flight in the afternoon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated July 3, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Santa Ana to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.8

Food

7.1

Crew

8.5

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.8

Food

7.1

Crew

8.5

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,266 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.8

Food

7.1

Crew

8.5

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,982 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.8

Food

7.1

Crew

8.5

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,861 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.8

Food

7.1

Crew

8.5

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.8

Food

7.1

Crew

8.5

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santa Ana to Greenville round-trip?

    American Airlines, at $354, was found to be the cheapest airline from Santa Ana to Greenville.Alternate airlines to your destination round-trip include Southwest and United Airlines. These flights start at 25% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santa Ana to Greenville that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Greenville.

  • Can I find deals for business class flights from Santa Ana to Greenville?

    Yes. Cheapflights offers flight deals from Santa Ana to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Santa Ana to Greenville (average of $329). Flying from Santa Ana to Greenville in March is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 3 airlines flying from Santa Ana to Greenville

Discover the top 3 airlines that operate flights from Santa Ana to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$352Average$446FlexibilityNo cancel feeOn-time71%
DeltaCheapest$356Average$387FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$361Average$526FlexibilityNo cancel feeOn-time69%

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