$210+ Cheap flights from Medford to Greenville (MFR - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — GSP
Jun 2 — Jun 91
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Medford to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to Greenville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Medford to GreenvilleExplore the most affordable flight options available from Medford to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
Explore the most affordable flight options available from Medford to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:26 pm
MFR
- GSP
2 stops12h 17m
United Airlines
Sat 9/262:23 pm
GSP
- MFR
2 stops11h 36m
United Airlines
Deal found 5/2![United Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:00 am
MFR
- GSP
1 stop6h 49m
United Airlines
Sun 5/174:35 pm
GSP
- MFR
1 stop7h 56m
United Airlines
Deal found 4/28![United Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:00 am
MFR
- GSP
1 stop7h 19m
United Airlines
Tue 6/94:15 pm
GSP
- MFR
1 stop8h 01m
United Airlines
Deal found 5/2![United Airlines logo]()
$633
This Alaska Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:08 am
MFR
- GSP
2 stops12h 48m
Alaska Airlines
Tue 6/911:33 am
GSP
- MFR
2 stops10h 06m
Alaska Airlines
Deal found 5/3![Alaska Airlines logo]()
$688
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
MFR
- GSP
2 stops14h 29m
United Airlines
Sat 6/204:15 pm
GSP
- MFR
1 stop8h 02m
United Airlines
Deal found 5/1![United Airlines logo]()
$728
Best flights from Medford to GreenvilleDiscover carefully curated flight deals from Medford to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
Discover carefully curated flight deals from Medford to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:06 pm
MFR
- GSP
3 stops16h 44m
United Airlines
Sat 9/262:23 pm
GSP
- MFR
2 stops11h 36m
United Airlines
Deal found 5/2![United Airlines logo]()
$483
This Alaska Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:41 pm
MFR
- GSP
2 stops14h 09m
Alaska Airlines
Tue 6/911:34 am
GSP
- MFR
2 stops10h 05m
Alaska Airlines
Deal found 5/2![Alaska Airlines logo]()
$668
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:15 am
MFR
- GSP
2 stops12h 23m
Delta
Sun 5/175:40 am
GSP
- MFR
2 stops9h 01m
Delta
Deal found 4/28![Delta logo]()
$743
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:00 am
MFR
- GSP
1 stop7h 19m
United Airlines
Tue 6/910:30 am
GSP
- MFR
2 stops15h 29m
United Airlines
Deal found 4/29![United Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:00 am
MFR
- GSP
2 stops15h 05m
United Airlines
Sun 5/174:35 pm
GSP
- MFR
1 stop7h 56m
United Airlines
Deal found 4/28![United Airlines logo]()
$668
Last-minute flights from Medford to GreenvilleDiscover last-minute flight deals from Medford to Greenville. Data last updated May 3, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to Greenville. Data last updated May 3, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:00 am
MFR
- GSP
1 stop6h 49m
United Airlines
Sun 5/174:35 pm
GSP
- MFR
1 stop7h 56m
United Airlines
Deal found 4/28![United Airlines logo]()
$625
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:15 am
MFR
- GSP
2 stops12h 23m
Delta
Sun 5/175:40 am
GSP
- MFR
2 stops9h 01m
Delta
Deal found 4/28![Delta logo]()
$743
One-way flights from Medford to GreenvilleSearch for one-way flight options from Medford to Greenville. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
Search for one-way flight options from Medford to Greenville. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:16 pm
MFR
- GSP
2 stops55h 17m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:16 pm
MFR
- GSP
2 stops37h 02m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:16 pm
MFR
- GSP
2 stops55h 17m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$300
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
MFR
- GSP
2 stops12h 23m
Delta
Deal found 4/30![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:21 pm
MFR
- GSP
2 stops19h 14m
Delta
Deal found 4/30![Delta logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:39 pm
MFR
- GSP
3 stops36h 54m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:11 pm
MFR
- GSP
3 stops17h 00m
United Airlines
Deal found 4/30![United Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:01 am
MFR
- GSP
2 stops14h 58m
Delta
Deal found 5/1![Delta logo]()
$366
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:15 am
MFR
- GSP
2 stops23h 49m
Delta
Deal found 4/30![Delta logo]()
$368
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:00 am
MFR
- GSP
1 stop7h 19m
United Airlines
Deal found 4/30![United Airlines logo]()
$374
Find flight deals from Medford to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $367 (United Airlines) |
One-way from | $210 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Medford to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Sat 9/12
2:06 pm-9:50 am
3 stops16h 44m
Greenville
Sat 9/26
2:23 pm-10:59 pm
2 stops11h 36m
$483
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Thu 6/4
5:00 am-3:19 pm
1 stop7h 19m
Greenville
Tue 6/9
10:30 am-10:59 pm
2 stops15h 29m
$625
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Thu 6/4
5:41 pm-10:50 am
2 stops14h 09m
Greenville
Tue 6/9
11:34 am-6:39 pm
2 stops10h 05m
$668
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Wed 5/13
5:00 am-11:05 pm
2 stops15h 05m
Greenville
Sun 5/17
4:35 pm-9:31 pm
1 stop7h 56m
$668
Quickest round-trip
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Wed 5/13
6:15 am-9:38 pm
2 stops12h 23m
Greenville
Sun 5/17
5:40 am-11:41 am
2 stops9h 01m
$743
Cheapest one-way
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Tue 5/26
12:21 pm-10:35 am
2 stops19h 14m
$316
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Wed 6/17
6:01 am-11:59 pm
2 stops14h 58m
$366
Quickest one-way
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Wed 5/27
5:00 am-3:19 pm
1 stop7h 19m
$374
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Thu 6/18
6:01 am-9:48 pm
2 stops12h 47m
$379
MedfordGreenville
MFR - GSP
MFRGSP
Medford
Fri 6/12
6:01 am-9:48 pm
2 stops12h 47m
$379
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Medford to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Greenville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Medford with our price prediction graph.
MFR-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated May 3, 2026.
Read through reviews of airlines operating flights from Medford to Greenville, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Overall
7.4
Comfort
7.3
Crew
8.1
Food
6.6
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Boarding
7.7
Entertainment
7.1
Overall
7.4
Comfort
7.3
Crew
8.1
Food
6.6
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Related info for your journey
Find useful and relevant information for your journey from Medford to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Greenville flight routes
Other flight options
Other flights from Medford
Popular flights
Alternative routes for Medford to Greenville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Greenville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Medford to Greenville by cabin class
Find flights from Medford to Greenville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 3, 2026.
Medford and Greenville flights
Browse other Medford and Greenville flight options. Last updated on May 3, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on May 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Medford to Greenville
Discover the top airline that operate flights from Medford to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$360 | Average$698 | FlexibilityNo cancel fee | On-time69% |