South Carolina

$457+ Cheap flights from Medford (MFR) to South Carolina

MFR — CHS
Dec 11 — Dec 181
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Cheap flight deals from Medford to South Carolina

Cheapest flights from Medford to South Carolina

Sat 12/55:00 am -
1 stop7h 12m
Tue 12/84:18 pm -
1 stop8h 08m
Deal found 11/10$549
Sat 11/215:01 am -
1 stop7h 02m
Wed 11/254:29 pm -
1 stop7h 49m
Deal found 11/6$569
Thu 11/125:01 am -
1 stop7h 05m
Tue 11/174:15 pm -
1 stop8h 03m
Deal found 11/10$611
Mon 12/217:20 pm -
2 stops11h 08m
Sat 1/27:37 pm -
2 stops28h 48m
Deal found 11/10$1,006

Find flight deals from Medford to South Carolina

Round-trip from

$454
(United Airlines)
From Medford to South Carolina

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordCharleston

MFR Medford - CHS Charleston

MFRCHS

Medford

Sat 4/3

3:21 pm-10:59 pm

2 stops28h 38m

Charleston

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$457
Quickest round-trip

MedfordCharleston

MFR Medford - CHS Charleston

MFRCHS

Medford

Sat 4/3

6:34 pm-12:02 pm

2 stops14h 28m

Charleston

Wed 12/31

12:00 am-9:00 pm

Nonstop0h 00m

$464

MedfordCharleston

MFR Medford - CHS Charleston

MFRCHS

Medford

Wed 3/17

1:32 pm-5:18 pm

1 stop24h 46m

Charleston

Wed 3/24

6:14 pm-11:59 pm

1 stop8h 45m

$505

MedfordCharleston

MFR Medford - CHS Charleston

MFRCHS

Medford

Fri 3/26

6:00 am-5:18 pm

1 stop8h 18m

Charleston

Fri 4/2

6:14 pm-11:59 pm

1 stop8h 45m

$513

MedfordGreenville

MFR Medford - GSP Greenville

MFRGSP

Medford

Sat 12/5

5:00 am-3:12 pm

1 stop7h 12m

Greenville

Tue 12/8

4:18 pm-9:26 pm

1 stop8h 08m

$549

MedfordCharleston

MFR Medford - CHS Charleston

MFRCHS

Medford

Wed 3/17

6:00 am-10:57 pm

2 stops13h 57m

Charleston

Wed 3/24

4:00 pm-9:25 pm

1 stop8h 25m

$560

MedfordGreenville

MFR Medford - GSP Greenville

MFRGSP

Medford

Sat 11/21

5:01 am-3:03 pm

1 stop7h 02m

Greenville

Wed 11/25

4:29 pm-9:18 pm

1 stop7h 49m

$569

MedfordCharleston

MFR Medford - CHS Charleston

MFRCHS

Medford

Wed 4/7

5:10 am-2:57 pm

1 stop6h 47m

Charleston

Sun 4/11

5:40 pm-11:09 pm

1 stop8h 29m

$625

MedfordGreenville

MFR Medford - GSP Greenville

MFRGSP

Medford

Tue 5/4

6:34 pm-9:56 am

2 stops12h 22m

Greenville

Tue 5/18

4:15 pm-9:10 pm

1 stop7h 55m

$639

MedfordCharleston

MFR Medford - CHS Charleston

MFRCHS

Medford

Fri 3/26

7:45 pm-11:04 am

2 stops12h 19m

Charleston

Fri 4/2

11:55 am-11:09 pm

2 stops14h 14m

$949

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Sorted by cheapest first

Best time to book a flight from Medford to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Medford with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Medford to South Carolina

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with United Airlines from Medford to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.7

Boarding

7.7

Overall

7.3

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.7

Boarding

7.7

Overall

7.3

Reviews

1 / 20
8.0
Excellent

Asha,Sep 2026

LGA - IAH

The flight was on time and boardi g was very organized and timely. Snacks are awful and having one little glass of juice was terrible. Fortunately, I had my water to keep me hydrated.

Related info for your journey

  • What airport do you fly from for flights from Medford to South Carolina?

    Medford (MFR), located 3.0 mi from the city center, is the airport you fly out of when you book flights from Medford to South Carolina.

  • How long is the flight from Medford to South Carolina?

    Airlines like United Airlines and Alaska Airlines fly from Medford to South Carolina in about 15h 09m. The time it takes to get you to your destination can typically vary by up to 9h 37m. Airlines will cover a distance of 2404 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Medford to South Carolina one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $124. Aeromexico flights start at $148 while deals on Alaska Airlines start at $150 one-way.

  • What are the most popular routes from Medford to South Carolina?

  • Can I find deals for flights from Medford to South Carolina that include hotel bookings?

    Yes. In addition to deals on Medford to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South Carolina.

  • Can I find deals for business class flights from Medford to South Carolina?

    Yes. Cheapflights offers flight deals from Medford to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Medford to South Carolina

Top airline flying from Medford to South Carolina

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$384Average$669FlexibilityNo cancel feeOn-time69%

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