$193+ Cheap flights from Medford (MFR) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — CHS
Sep 8 — Sep 151
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Medford to South CarolinaExplore the most affordable flight options available from Medford to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
Explore the most affordable flight options available from Medford to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:15 am -
1 stop8h 19m
Mon 10/265:44 pm -
1 stop9h 11m
Deal found 8/8![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:15 am -
1 stop8h 19m
Wed 10/285:09 pm -
2 stops9h 46m
Deal found 8/8![Delta logo]()
$384
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am -
2 stops9h 56m
Wed 9/91:00 pm -
2 stops11h 08m
Deal found 8/7![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:25 pm -
2 stops12h 36m
Tue 10/275:44 pm -
1 stop9h 11m
Deal found 8/8![Delta logo]()
$414
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:28 pm -
2 stops13h 43m
Fri 9/115:00 pm -
2 stops9h 55m
Deal found 8/7![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:00 pm -
1 stop7h 26m
Fri 9/118:48 am -
1 stop7h 13m
Deal found 8/7![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am -
1 stop6h 48m
Tue 8/254:33 pm -
1 stop7h 35m
Deal found 8/9![United Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:20 am -
2 stops13h 57m
Tue 8/2510:12 am -
2 stops12h 08m
Deal found 8/9![American Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:01 am -
1 stop7h 02m
Sat 11/144:29 pm -
1 stop7h 49m
Deal found 8/4![United Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:01 am -
1 stop7h 15m
Wed 11/118:36 am -
1 stop7h 34m
Deal found 8/6![United Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:10 am -
1 stop7h 00m
Sat 12/124:15 pm -
1 stop7h 55m
Deal found 8/6![United Airlines logo]()
$566
Best flights from Medford to South CarolinaDiscover carefully curated flight deals from Medford to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
Discover carefully curated flight deals from Medford to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:00 am -
1 stop7h 16m
Wed 9/98:48 am -
1 stop7h 13m
Deal found 8/7![United Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:15 am -
1 stop8h 19m
Sat 10/171:19 pm -
2 stops12h 59m
Deal found 8/4![Delta logo]()
$384
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:28 pm -
2 stops13h 43m
Fri 9/115:00 pm -
2 stops9h 55m
Deal found 8/7![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:01 am -
1 stop7h 02m
Sat 11/144:29 pm -
1 stop7h 49m
Deal found 8/4![United Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:34 pm -
2 stops12h 36m
Sat 2/610:20 am -
2 stops13h 50m
Deal found 8/4![United Airlines logo]()
$487
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:01 am -
1 stop7h 15m
Wed 11/118:36 am -
1 stop7h 34m
Deal found 8/8![United Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:08 pm -
3 stops16h 36m
Tue 9/299:54 am -
2 stops14h 20m
Deal found 8/4![United Airlines logo]()
$505
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:08 pm -
3 stops15h 58m
Wed 10/288:10 am -
2 stops12h 50m
Deal found 8/8![United Airlines logo]()
$505
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:10 am -
1 stop7h 00m
Sat 12/124:15 pm -
1 stop7h 55m
Deal found 8/6![United Airlines logo]()
$566
Last-minute flights from Medford to South CarolinaDiscover last-minute flight deals from Medford to South Carolina. Data last updated August 9, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to South Carolina. Data last updated August 9, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:00 am -
1 stop6h 48m
Tue 8/254:33 pm -
1 stop7h 35m
Deal found 8/9![United Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:20 am -
2 stops13h 57m
Tue 8/2510:12 am -
2 stops12h 08m
Deal found 8/9![American Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:00 am -
1 stop7h 16m
Wed 9/98:48 am -
1 stop7h 13m
Deal found 8/7![United Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:28 pm -
2 stops13h 43m
Fri 9/115:00 pm -
2 stops9h 55m
Deal found 8/7![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:00 pm -
1 stop7h 26m
Fri 9/118:48 am -
1 stop7h 13m
Deal found 8/7![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:00 am -
1 stop7h 14m
Tue 9/298:46 am -
1 stop7h 16m
Deal found 8/4![United Airlines logo]()
$489
One-way flights from Medford to South CarolinaSearch for one-way flight options from Medford to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
Search for one-way flight options from Medford to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:52 pm -
2 stops17h 59m
Deal found 8/7![Multiple Airlines logo]()
$193
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:15 am -
1 stop8h 19m
Deal found 8/4![Delta logo]()
$379
Find flight deals from Medford to South Carolina
Keep the following information in mind while searching for Medford to South Carolina flight deals. Data was last updated August 9, 2026.
Round-trip from | $379 (Delta) |
|---|---|
One-way from | $193 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MedfordCharlotte
MFR Medford - CLT Charlotte Douglas
MFRCLT
Medford
Wed 9/2
5:00 am-3:16 pm
1 stop7h 16m
Charlotte Douglas
Wed 9/9
8:48 am-1:01 pm
1 stop7h 13m
$379
MedfordCharlotte
MFR Medford - CLT Charlotte Douglas
MFRCLT
Medford
Sun 10/11
5:15 am-4:34 pm
1 stop8h 19m
Charlotte Douglas
Sat 10/17
1:19 pm-11:18 pm
2 stops12h 59m
$384
MedfordCharlotte
MFR Medford - CLT Charlotte Douglas
MFRCLT
Medford
Fri 9/4
5:28 pm-10:11 am
2 stops13h 43m
Charlotte Douglas
Fri 9/11
5:00 pm-11:55 pm
2 stops9h 55m
$449
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Sun 11/1
5:01 am-3:03 pm
1 stop7h 02m
Greenville
Sat 11/14
4:29 pm-9:18 pm
1 stop7h 49m
$483
MedfordColumbia
MFR Medford - CAE Columbia Metropolitan
MFRCAE
Medford
Tue 2/2
6:34 pm-10:10 am
2 stops12h 36m
Columbia Metropolitan
Sat 2/6
10:20 am-9:10 pm
2 stops13h 50m
$487
MedfordCharlotte
MFR Medford - CLT Charlotte Douglas
MFRCLT
Medford
Sat 11/7
5:01 am-3:16 pm
1 stop7h 15m
Charlotte Douglas
Wed 11/11
8:36 am-1:10 pm
1 stop7h 34m
$489
MedfordCharlotte
MFR Medford - CLT Charlotte Douglas
MFRCLT
Medford
Sat 9/26
2:08 pm-9:44 am
3 stops16h 36m
Charlotte Douglas
Tue 9/29
9:54 am-9:14 pm
2 stops14h 20m
$505
MedfordCharlotte
MFR Medford - CLT Charlotte Douglas
MFRCLT
Medford
Tue 10/20
2:08 pm-9:06 am
3 stops15h 58m
Charlotte Douglas
Wed 10/28
8:10 am-6:00 pm
2 stops12h 50m
$505
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Tue 12/8
5:10 am-3:10 pm
1 stop7h 00m
Greenville
Sat 12/12
4:15 pm-9:10 pm
1 stop7h 55m
$566
Cheapest one-way
MedfordCharlotte
MFR Medford - CLT Charlotte Douglas
MFRCLT
Medford
Fri 10/16
9:52 pm-6:51 pm
2 stops17h 59m
$193
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Medford to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Medford with our price prediction graph.
MFR-CLT
MFR-GSP
MFR-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Medford to South Carolina
MFR-USSC
MFR-CLT
MFR-GSP
MFR-CAE
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 9, 2026.
Get a feel of what it's like to fly with United Airlines from Medford to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Crew
8.1
Comfort
7.3
Entertainment
7.1
Food
6.7
Overall
7.4
Reviews
1 / 20
2.0
MediocreDawn,Aug 2026
ORD - DEN
Boarding
7.7
Crew
8.1
Comfort
7.3
Entertainment
7.1
Food
6.7
Overall
7.4
Reviews
1 / 20
2.0
MediocreDawn,Aug 2026
ORD - DEN
Related info for your journey
Find useful and relevant information for your journey from Medford to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Medford to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Medford to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Medford and South Carolina flights
Browse other Medford and South Carolina flight options. Last updated on August 9, 2026.
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Medford to South Carolina flights
Consider these flights traveling from Medford to South Carolina.
Top airline flying from Medford to South Carolina
Discover the top airline that operate flights from Medford to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$354 | Average$669 | FlexibilityNo cancel fee | On-time69% |