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South Carolina

$195+ Cheap flights from Medford (MFR) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — CHS
Jul 25 — Aug 11
Sat 7/25
Sat 8/1
1 adult, Economy
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Cheap flight deals from Medford to South Carolina

Cheapest flights from Medford to South Carolina
Explore the most affordable flight options available from Medford to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.

This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:15 am
MFR
-
CLT
2 stops12h 37m
Delta
Wed 9/305:50 pm
CLT
-
MFR
1 stop9h 05m
Delta
Deal found 6/22$374
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:08 pm
MFR
-
CLT
1 stop7h 21m
United Airlines
Wed 9/308:46 am
CLT
-
MFR
1 stop7h 15m
United Airlines
Deal found 6/22$389
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:24 pm
MFR
-
CLT
2 stops12h 25m
Delta
Mon 7/202:22 pm
CLT
-
MFR
2 stops11h 49m
Delta
Deal found 6/25$419
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:10 am
MFR
-
GSP
1 stop6h 38m
United Airlines
Sat 10/314:29 pm
GSP
-
MFR
1 stop7h 53m
United Airlines
Deal found 6/22$467
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:24 pm
MFR
-
CLT
2 stops12h 34m
Delta
Mon 7/206:10 pm
CLT
-
MFR
1 stop8h 44m
Delta
Deal found 6/25$469
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:00 pm
MFR
-
CAE
2 stops11h 47m
United Airlines
Wed 11/410:10 am
CAE
-
MFR
2 stops14h 12m
United Airlines
Deal found 6/24$477
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:00 am
MFR
-
CLT
1 stop9h 15m
American Airlines
Wed 9/301:13 pm
CLT
-
MFR
1 stop8h 58m
American Airlines
Deal found 6/22$479
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:10 am
MFR
-
CLT
2 stops13h 35m
United Airlines
Sat 10/314:19 pm
CLT
-
MFR
1 stop8h 03m
United Airlines
Deal found 6/22$484
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
MFR
-
CLT
2 stops11h 58m
Delta
Wed 7/152:57 pm
CLT
-
MFR
2 stops11h 57m
Delta
Deal found 6/24$494
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:00 am
MFR
-
CLT
2 stops13h 59m
United Airlines
Sat 7/184:08 pm
CLT
-
MFR
1 stop8h 01m
United Airlines
Deal found 6/23$496
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:20 am
MFR
-
CLT
1 stop8h 36m
Delta
Mon 7/136:10 pm
CLT
-
MFR
1 stop8h 44m
Delta
Deal found 6/24$499
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
MFR
-
CLT
2 stops11h 58m
Delta
Mon 7/136:10 pm
CLT
-
MFR
1 stop8h 44m
Delta
Deal found 6/24$504

Find flight deals from Medford to South Carolina

Keep the following information in mind while searching for Medford to South Carolina flight deals. Data was last updated June 25, 2026.

Round-trip from

$374
(Delta)

One-way from

$195
(Kiwi.com)
From Medford to South Carolina
Search Deals
One-way flight from Medford to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 9/16

6:15 am-9:52 pm

2 stops12h 37m

Charlotte Douglas

Wed 9/30

5:50 pm-11:55 pm

1 stop9h 05m

$374

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 9/16

1:08 pm-11:29 pm

1 stop7h 21m

Charlotte Douglas

Wed 9/30

8:46 am-1:01 pm

1 stop7h 15m

$389

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Tue 7/14

5:24 pm-8:49 am

2 stops12h 25m

Charlotte Douglas

Mon 7/20

2:22 pm-11:11 pm

2 stops11h 49m

$419
Quickest round-trip

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 10/27

5:10 am-2:48 pm

1 stop6h 38m

Greenville

Sat 10/31

4:29 pm-9:22 pm

1 stop7h 53m

$467

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Fri 7/10

5:24 pm-8:58 am

2 stops12h 34m

Charlotte Douglas

Mon 7/20

6:10 pm-11:54 pm

1 stop8h 44m

$469

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Sat 10/31

8:00 pm-10:47 am

2 stops11h 47m

Columbia Metropolitan

Wed 11/4

10:10 am-9:22 pm

2 stops14h 12m

$477

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Tue 10/27

5:10 am-9:45 pm

2 stops13h 35m

Charlotte Douglas

Sat 10/31

4:19 pm-9:22 pm

1 stop8h 03m

$484

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sat 7/11

5:00 am-9:59 pm

2 stops13h 59m

Charlotte Douglas

Sat 7/18

4:08 pm-9:09 pm

1 stop8h 01m

$496

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sat 7/11

5:00 am-9:59 pm

2 stops13h 59m

Charlotte Douglas

Fri 7/17

4:08 pm-9:16 pm

1 stop8h 08m

$596
Cheapest one-way

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sun 10/4

8:57 pm-9:46 pm

2 stops21h 49m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/22

Showing 1-10 of 18 resultsSorted by cheapest first
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Best time to book a flight from Medford to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Medford to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Medford to South Carolina?

    Medford (MFR), located 3.0 mi from the city center, is the airport you fly out of when you book flights from Medford to South Carolina.

  • How long is the flight from Medford to South Carolina?

    Airlines like Delta and United Airlines fly from Medford to South Carolina in about 7h 21m. The time it takes to get you to your destination can typically vary by up to 5h 16m. Airlines will cover a distance of 2286 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Medford to South Carolina one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $124. Aeromexico flights start at $148 while deals on Alaska Airlines start at $150 one-way.

  • What are the most popular routes from Medford to South Carolina?

    The most popular flight routes from Medford to South Carolina are Medford - Charlotte Douglas, Medford - Columbia Metropolitan and Medford - Greenville.

  • Can I find deals for flights from Medford to South Carolina that include hotel bookings?

    Yes. In addition to deals on Medford to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to South Carolina.

  • Can I find deals for business class flights from Medford to South Carolina?

    Yes. Cheapflights offers flight deals from Medford to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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