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$141+ Cheap flights from Harrisburg to Greenville (MDT - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — GSP
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Cheap flight deals from Harrisburg to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(United Airlines)

One-way from

$141
(Kiwi.com)

Popular in

October

Cheapest in

July

Average price

$404
Provider with most accurate pricing for Harrisburg-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Greenville flights.
Search Deals
From Harrisburg to Greenville
Search Deals
One-way flight from Harrisburg to Greenville
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($75 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Harrisburg to Greenville

Cheapest flights from Harrisburg to Greenville
Explore the most affordable flight options available from Harrisburg to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Delta deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:27 pmMDT - GSP
1 stop4h 13mDelta
Sat 12/135:35 amGSP - MDT
1 stop6h 46mDelta
Deal found 11/17$229
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:00 amMDT - GSP
1 stop3h 25mAmerican Airlines
Thu 12/116:39 amGSP - MDT
1 stop4h 03mAmerican Airlines
Deal found 11/16$244
This Mytrip deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:30 amMDT - GSP
2 stops28h 40mMultiple Airlines
Sun 12/212:54 pmGSP - MDT
1 stop5h 09mMultiple Airlines
Deal found 11/16$278
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:12 pmMDT - GSP
1 stop4h 33mDelta
Sun 11/236:45 amGSP - MDT
1 stop4h 14mDelta
Deal found 11/16$294
This Mytrip deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:47 amMDT - GSP
1 stop11h 27mAllegiant Air
Sun 12/212:54 pmGSP - MDT
1 stop5h 09mAllegiant Air
Deal found 11/16$302
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:27 pmMDT - GSP
1 stop4h 13mDelta
Mon 12/86:29 pmGSP - MDT
1 stop4h 38mDelta
Deal found 11/16$304
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:00 amMDT - GSP
1 stop5h 50mAmerican Airlines
Sat 11/226:00 amGSP - MDT
1 stop4h 24mAmerican Airlines
Deal found 11/16$319
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:00 amMDT - GSP
1 stop5h 51mAmerican Airlines
Mon 12/86:21 pmGSP - MDT
1 stop3h 56mAmerican Airlines
Deal found 11/17$329
This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:30 amMDT - GSP
1 stop5h 14mUnited Airlines
Sat 12/610:00 amGSP - MDT
1 stop3h 52mUnited Airlines
Deal found 11/17$385
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/162:55 pmMDT - GSP
2 stops8h 13mAmerican Airlines
Sun 12/286:26 pmGSP - MDT
1 stop3h 46mAmerican Airlines
Deal found 11/16$390
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:00 amMDT - GSP
1 stop3h 36mAmerican Airlines
Sat 12/275:39 amGSP - MDT
1 stop3h 31mAmerican Airlines
Deal found 11/16$489
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:40 pmMDT - GSP
1 stop6h 02mAmerican Airlines
Sun 11/306:00 amGSP - MDT
1 stop4h 24mAmerican Airlines
Deal found 11/17$504

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Harrisburg to Greenville that are best for you.

Fly from

Harrisburg

Fly to

Greenville

Route

Depart

Return

Price

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 2/14

6:46 am-10:42 am

1 stop3h 56m

Greenville

Sat 2/21

7:03 am-10:56 am

1 stop3h 53m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 12/12

7:27 pm-11:40 pm

1 stop4h 13m

Greenville

Sat 12/13

5:35 am-12:21 pm

1 stop6h 46m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 12/12

6:40 am-10:34 am

1 stop3h 54m

Greenville

Sat 12/13

6:39 am-10:42 am

1 stop4h 03m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 1/31

12:53 pm-5:09 pm

1 stop4h 16m

Greenville

Tue 2/3

5:40 pm-11:37 pm

1 stop5h 57m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 12/4

5:00 am-8:25 am

1 stop3h 25m

Greenville

Thu 12/11

6:39 am-10:42 am

1 stop4h 03m

$244

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 1/17

4:49 pm-8:48 pm

1 stop3h 59m

Greenville

Sat 1/24

3:39 pm-10:27 pm

2 stops6h 48m

$266

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sun 12/14

9:30 am-2:10 pm

2 stops28h 40m

Greenville

Sun 12/21

2:54 pm-8:03 pm

1 stop5h 09m

$278

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 12/19

9:47 am-9:14 pm

1 stop11h 27m

Greenville

Sun 12/21

2:54 pm-8:03 pm

1 stop5h 09m

$302

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 12/4

7:27 pm-11:40 pm

1 stop4h 13m

Greenville

Mon 12/8

6:29 pm-11:07 pm

1 stop4h 38m

$304

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sun 1/4

5:00 am-8:36 am

1 stop3h 36m

Greenville

Sat 1/24

5:40 pm-11:58 pm

1 stop6h 18m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 18 results
1
2

Compare providers for flights from Harrisburg to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Greenville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Harrisburg-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Harrisburg-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Greenville

What is the cheapest month to book a flight from Harrisburg to Greenville?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $50). Flying from Harrisburg to Greenville in April is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to GSP?

Find hourly flight availability from Harrisburg to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

It’s typically best to fly out from Harrisburg to Greenville in the morning. Doing so could potentially save you 35% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 17, 2025.
Read through reviews of airlines operating flights from Harrisburg to Greenville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,015 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Greenville?

    For as low as $229, American Airlines can have you in Greenville from Harrisburg in 3h 56m. Harrisburg and Greenville are separated by a distance of 472 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to Greenville round-trip?

    Cheapflights users have booked flights from Harrisburg to Greenville round-trip from $228. Other airlines that can offer you cheap pricing are Delta, from $228, and United Airlines, from $233. You may be able to fly from Harrisburg to Greenville for 32% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Greenville that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Greenville.

  • Can I find deals for business class flights from Harrisburg to Greenville?

    Yes. Cheapflights offers flight deals from Harrisburg to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $50). Flying from Harrisburg to Greenville in April is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Harrisburg to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Harrisburg to Greenville

Discover the top 3 airlines that operate flights from Harrisburg to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$319FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$293FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$233Average$337FlexibilityNo cancel feeOn-time69%

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