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$244+ Cheap flights from Harrisburg to Greenville (MDT - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — GSP
feb. 20 — feb. 271
vie. 2/20
vie. 2/27
1 adult, Economy
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1. Tell us where you want to go

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Cheap flight deals from Harrisburg to Greenville

Cheapest flights from Harrisburg to Greenville
Explore the most affordable flight options available from Harrisburg to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 21, 2026.

This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/204:39 pm
MDT
-
GSP
1 stop5h 45m
Delta
mié. 2/256:49 am
GSP
-
MDT
1 stop4h 21m
Delta
Deal found 1/21$244
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 1/3112:53 pm
MDT
-
GSP
1 stop4h 16m
American Airlines
mar. 2/36:00 am
GSP
-
MDT
1 stop4h 17m
American Airlines
Deal found 1/19$264
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/202:59 pm
MDT
-
GSP
1 stop5h 47m
American Airlines
mié. 2/2510:50 am
GSP
-
MDT
1 stop3h 44m
American Airlines
Deal found 1/18$274
This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/135:55 pm
MDT
-
GSP
1 stop5h 48m
Delta
mar. 2/176:49 am
GSP
-
MDT
1 stop4h 21m
Delta
Deal found 1/18$299
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/196:57 pm
MDT
-
GSP
1 stop24h 41m
Multiple Airlines
lun. 2/238:18 pm
GSP
-
MDT
1 stop14h 14m
Multiple Airlines
Deal found 1/18$301
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/156:00 am
MDT
-
GSP
1 stop6h 20m
Delta
dom. 4/197:59 pm
GSP
-
MDT
1 stop3h 48m
Delta
Deal found 1/19$304
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/1811:09 am
MDT
-
GSP
1 stop24h 54m
Multiple Airlines
lun. 2/238:18 pm
GSP
-
MDT
1 stop14h 14m
Multiple Airlines
Deal found 1/18$306
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/143:33 pm
MDT
-
GSP
1 stop4h 29m
American Airlines
mar. 2/176:00 am
GSP
-
MDT
1 stop3h 26m
American Airlines
Deal found 1/18$309
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/159:48 am
MDT
-
GSP
2 stops10h 14m
American Airlines
mar. 2/245:20 am
GSP
-
MDT
1 stop6h 41m
American Airlines
Deal found 1/20$310

Find flight deals from Harrisburg to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$244
(Delta)

Popular in

October

Cheapest in

July

Average price

$341
Provider with most accurate pricing for Harrisburg-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Greenville flights.
Search Deals
From Harrisburg to Greenville
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($82 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
Use the filters below to find and compare flights from Harrisburg to Greenville that are best for you.

Fly from

Harrisburg

Fly to

Greenville

Route

Depart

Return

Price

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

vie. 2/20

4:39 pm-10:24 pm

1 stop5h 45m

Greenville

mié. 2/25

5:40 am-11:10 am

1 stop5h 30m

$244

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

sáb. 1/31

12:53 pm-7:07 pm

1 stop6h 14m

Greenville

mar. 2/3

6:00 am-10:54 am

1 stop4h 54m

$264

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

vie. 2/20

2:59 pm-8:46 pm

1 stop5h 47m

Greenville

mié. 2/25

10:50 am-2:34 pm

1 stop3h 44m

$274

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

dom. 2/15

6:34 am-11:13 am

1 stop4h 39m

Greenville

mar. 2/24

6:49 am-11:10 am

1 stop4h 21m

$299

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

vie. 2/13

5:55 pm-11:43 pm

1 stop5h 48m

Greenville

mar. 2/17

6:49 am-11:10 am

1 stop4h 21m

$299

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

mié. 3/4

12:08 pm-6:37 pm

1 stop6h 29m

Greenville

mié. 3/11

6:14 pm-10:50 pm

1 stop4h 36m

$299

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

mar. 3/3

12:08 pm-6:37 pm

1 stop6h 29m

Greenville

mié. 3/11

6:14 pm-10:50 pm

1 stop4h 36m

$299

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

mié. 4/15

6:00 am-12:20 pm

1 stop6h 20m

Greenville

dom. 4/19

7:59 pm-11:47 pm

1 stop3h 48m

$304

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

dom. 2/15

9:48 am-8:02 pm

2 stops10h 14m

Greenville

mar. 2/24

5:20 am-12:01 pm

1 stop6h 41m

$310

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Compare providers for flights from Harrisburg to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Greenville flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Greenville

What is the cheapest month to book a flight from Harrisburg to Greenville?

Currently, February is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $63). Flying from Harrisburg to Greenville in April is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated enero 21, 2026.
Read through reviews of airlines operating flights from Harrisburg to Greenville, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,191 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,191 reviews
United Airlines
7.4
Good
9,191 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,174 reviews
United Airlines
7.4
Good
9,191 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Greenville?

    For as low as $244, Delta can have you in Greenville from Harrisburg in 5h 45m. Harrisburg and Greenville are separated by a distance of 472 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to Greenville round-trip?

    Cheapflights users have booked flights from Harrisburg to Greenville round-trip from $228. Another airline that can offer you cheap pricing is United Airlines. You may be able to fly from Harrisburg to Greenville for 31% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Greenville that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Greenville.

  • Can I find deals for business class flights from Harrisburg to Greenville?

    Yes. Cheapflights offers flight deals from Harrisburg to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Greenville?

    Currently, February is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $63). Flying from Harrisburg to Greenville in April is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Harrisburg to Greenville

Discover the top 2 airlines that operate flights from Harrisburg to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$290FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$293FlexibilityNo cancel feeOn-time69%

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