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$249+ Cheap flights from Harrisburg to Greenville (MDT - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — GSP
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Harrisburg to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

Popular in

October

Cheapest in

July

Average price

$341
Provider with most accurate pricing for Harrisburg-Greenville flight deals.
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Provider most trusted by Cheapflights users for Harrisburg-Greenville flights.
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From Harrisburg to Greenville
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($82 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Harrisburg to Greenville

Cheapest flights from Harrisburg to Greenville
Explore the most affordable flight options available from Harrisburg to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/314:49 pmMDT - GSP
1 stop3h 56mAmerican Airlines
Tue 2/36:00 amGSP - MDT
1 stop4h 17mAmerican Airlines
Deal found 1/7$249
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/232:28 pmMDT - GSP
1 stop5h 01mUnited Airlines
Sat 1/246:35 amGSP - MDT
1 stop7h 40mUnited Airlines
Deal found 1/7$255
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:02 pmMDT - GSP
1 stop5h 48mDelta
Mon 1/267:46 pmGSP - MDT
1 stop3h 40mDelta
Deal found 1/7$259
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/235:47 amMDT - GSP
1 stop5h 37mAmerican Airlines
Sat 1/241:45 pmGSP - MDT
2 stops8h 42mAmerican Airlines
Deal found 1/7$264
This Delta deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/165:05 pmMDT - GSP
1 stop5h 19mDelta
Mon 1/197:46 pmGSP - MDT
1 stop3h 40mDelta
Deal found 1/8$269
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:39 pmMDT - GSP
1 stop5h 45mDelta
Sun 2/225:40 amGSP - MDT
1 stop5h 36mDelta
Deal found 1/7$304
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/272:28 pmMDT - GSP
1 stop5h 01mUnited Airlines
Sat 1/316:35 amGSP - MDT
1 stop7h 40mUnited Airlines
Deal found 1/6$309
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/233:10 pmMDT - GSP
1 stop5h 37mUnited Airlines
Tue 1/2710:51 amGSP - MDT
1 stop5h 43mUnited Airlines
Deal found 1/8$319

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Harrisburg to Greenville that are best for you.

Fly from

Harrisburg

Fly to

Greenville

Route

Depart

Return

Price

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 1/30

3:03 pm-8:59 pm

1 stop5h 56m

Greenville

Sun 2/1

6:00 am-10:54 am

1 stop4h 54m

$249

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 1/31

4:49 pm-8:45 pm

1 stop3h 56m

Greenville

Tue 2/3

6:00 am-10:17 am

1 stop4h 17m

$249

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 1/23

2:28 pm-7:29 pm

1 stop5h 01m

Greenville

Sat 1/24

6:35 am-2:15 pm

1 stop7h 40m

$255

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 1/23

6:02 pm-11:50 pm

1 stop5h 48m

Greenville

Sat 1/24

6:45 pm-10:56 pm

1 stop4h 11m

$259

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 1/22

6:02 pm-11:50 pm

1 stop5h 48m

Greenville

Mon 1/26

7:46 pm-11:26 pm

1 stop3h 40m

$259

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 1/23

5:47 am-11:24 am

1 stop5h 37m

Greenville

Sat 1/24

1:45 pm-10:27 pm

2 stops8h 42m

$264

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 2/4

4:47 pm-8:45 pm

1 stop3h 58m

Greenville

Sun 2/8

8:16 am-2:38 pm

2 stops6h 22m

$279

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 2/19

4:39 pm-10:24 pm

1 stop5h 45m

Greenville

Sun 2/22

5:40 am-11:16 am

1 stop5h 36m

$304

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 1/27

2:28 pm-7:29 pm

1 stop5h 01m

Greenville

Sat 1/31

6:35 am-2:15 pm

1 stop7h 40m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/8

Compare providers for flights from Harrisburg to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Harrisburg-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Harrisburg-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Greenville

What is the cheapest month to book a flight from Harrisburg to Greenville?

Currently, February is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $63). Flying from Harrisburg to Greenville in April is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 8, 2026.
Read through reviews of airlines operating flights from Harrisburg to Greenville, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
United Airlines
7.4
Good
9,139 reviews
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
American Airlines
7.2
Good
11,095 reviews
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Greenville?

    For as low as $255, American Airlines can have you in Greenville from Harrisburg in 5h 01m. Harrisburg and Greenville are separated by a distance of 472 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to Greenville round-trip?

    Cheapflights users have booked flights from Harrisburg to Greenville round-trip from $228. Another airline that can offer you cheap pricing is United Airlines. You may be able to fly from Harrisburg to Greenville for 31% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Greenville that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Greenville.

  • Can I find deals for business class flights from Harrisburg to Greenville?

    Yes. Cheapflights offers flight deals from Harrisburg to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Greenville?

    Currently, February is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $63). Flying from Harrisburg to Greenville in April is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 2 airlines flying from Harrisburg to Greenville

Discover the top 2 airlines that operate flights from Harrisburg to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$311FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$293FlexibilityNo cancel feeOn-time69%

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