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Greenville

$166+ Cheap flights from Harrisburg to Greenville (MDT - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — GSP
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Harrisburg to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$229
(Delta)

One-way from

$166
(American Airlines)

Popular in

December

Cheapest in

July

Average price

$311
From Harrisburg to Greenville
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One-way flight from Harrisburg to Greenville
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Highest demand for flights based on searches. 8% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Harrisburg to Greenville

Cheapest flights from Harrisburg to Greenville
Explore the most affordable flight options available from Harrisburg to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:25 pmMDT - GSP
1 stop3h 53mDelta
Sat 10/115:16 pmGSP - MDT
1 stop5h 52mDelta
Deal found 9/15$229
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:23 pmMDT - GSP
1 stop4h 04mDelta
Tue 10/76:44 pmGSP - MDT
1 stop4h 16mDelta
Deal found 9/15$234
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:23 pmMDT - GSP
1 stop4h 04mDelta
Sun 10/55:30 amGSP - MDT
1 stop5h 26mDelta
Deal found 9/15$239
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:23 pmMDT - GSP
1 stop5h 11mDelta
Sat 9/275:21 pmGSP - MDT
1 stop6h 25mDelta
Deal found 9/15$269
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:25 pmMDT - GSP
1 stop5h 30mDelta
Sun 10/265:30 amGSP - MDT
1 stop5h 29mDelta
Deal found 9/14$278
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:00 amMDT - GSP
1 stop5h 24mDelta
Tue 10/76:44 pmGSP - MDT
1 stop4h 16mDelta
Deal found 9/15$284
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:23 pmMDT - GSP
1 stop5h 11mDelta
Mon 10/66:44 pmGSP - MDT
1 stop4h 16mDelta
Deal found 9/15$289
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:30 amMDT - GSP
1 stop5h 16mUnited Airlines
Sat 10/412:21 pmGSP - MDT
1 stop7h 36mUnited Airlines
Deal found 9/15$299
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:30 pmMDT - GSP
1 stop4h 28mAmerican Airlines
Sat 10/48:05 amGSP - MDT
2 stops7h 55mAmerican Airlines
Deal found 9/15$304
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/241:01 pmMDT - GSP
1 stop4h 51mAmerican Airlines
Sat 9/2712:20 pmGSP - MDT
2 stops5h 41mAmerican Airlines
Deal found 9/14$315
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/208:25 pmMDT - GSP
1 stop19h 03mAllegiant Air
Thu 10/233:37 pmGSP - MDT
1 stop16h 56mAllegiant Air
Deal found 9/15$327
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:00 amMDT - GSP
1 stop4h 09mDelta
Mon 10/206:44 pmGSP - MDT
1 stop4h 16mDelta
Deal found 9/15$334

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Harrisburg to Greenville that are best for you.

Fly from

Harrisburg

Fly to

Greenville

Route

Depart

Return

Price

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 10/7

6:00 am-12:47 pm

1 stop6h 47m

Greenville

Sat 10/11

5:16 pm-11:08 pm

1 stop5h 52m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 10/3

6:30 pm-10:58 pm

1 stop4h 28m

Greenville

Sun 10/5

5:06 am-9:15 am

1 stop4h 09m

$234

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 9/30

6:23 pm-11:34 pm

1 stop5h 11m

Greenville

Tue 10/7

6:44 pm-11:00 pm

1 stop4h 16m

$234

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Mon 9/29

6:23 pm-11:52 pm

1 stop5h 29m

Greenville

Tue 10/7

6:44 pm-11:00 pm

1 stop4h 16m

$234

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 10/1

6:23 pm-11:34 pm

1 stop5h 11m

Greenville

Tue 10/7

6:44 pm-11:00 pm

1 stop4h 16m

$234

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 9/30

6:10 am-10:44 am

1 stop4h 34m

Greenville

Sun 10/5

5:30 am-10:56 am

1 stop5h 26m

$239

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 10/1

6:10 am-10:44 am

1 stop4h 34m

Greenville

Sun 10/5

6:35 am-10:56 am

1 stop4h 21m

$239

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 10/3

6:23 pm-10:27 pm

1 stop4h 04m

Greenville

Sun 10/5

5:30 am-10:56 am

1 stop5h 26m

$239

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 9/24

6:23 pm-11:34 pm

1 stop5h 11m

Greenville

Sat 9/27

5:21 pm-11:46 pm

1 stop6h 25m

$269

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 10/22

6:25 pm-11:55 pm

1 stop5h 30m

Greenville

Sun 10/26

5:30 am-10:59 am

1 stop5h 29m

$278

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 15 results
1
2

Best time to book a flight from Harrisburg to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Greenville

What is the cheapest month to book a flight from Harrisburg to Greenville?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $321). Flying from Harrisburg to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to GSP?

Find hourly flight availability from Harrisburg to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

It’s typically best to fly out from Harrisburg to Greenville in the morning. Doing so could potentially save you 36% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Harrisburg to Greenville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Greenville?

    For as low as $234, Delta can have you in Greenville from Harrisburg in 4h 28m. Harrisburg and Greenville are separated by a distance of 472 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to Greenville round-trip?

    Cheapflights users have booked flights from Harrisburg to Greenville round-trip from $228. Other airlines that can offer you cheap pricing are Delta, from $228, and United Airlines, from $233. You may be able to fly from Harrisburg to Greenville for 26% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Greenville that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Greenville.

  • Can I find deals for business class flights from Harrisburg to Greenville?

    Yes. Cheapflights offers flight deals from Harrisburg to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $321). Flying from Harrisburg to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Harrisburg to Greenville

Discover the top 3 airlines that operate flights from Harrisburg to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$299FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$293FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$233Average$337FlexibilityNo cancel feeOn-time69%

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