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Grand Cayman

$102+ Cheap flights from South Carolina to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Find flight deals from South Carolina to Grand Cayman

Cheapest flights from South Carolina to Grand Cayman
Explore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:00 amCHS - GCM
1 stop8h 25mAmerican Airlines
Sat 11/2212:39 pmGCM - CHS
1 stop8h 45mAmerican Airlines
Deal found 11/2$313
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:10 pmCLT - GCM
2 stops17h 35mSpirit Airlines
Sun 12/142:40 pmGCM - CLT
1 stop9h 19mSpirit Airlines
Deal found 11/1$351
This Priceline deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:30 amCLT - GCM
1 stop26h 55mMultiple Airlines
Sun 12/142:40 pmGCM - CLT
1 stop9h 19mMultiple Airlines
Deal found 11/1$395
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:59 pmCLT - GCM
1 stop19h 46mMultiple Airlines
Wed 12/1011:30 amGCM - CLT
1 stop25h 11mMultiple Airlines
Deal found 11/3$408
This Priceline deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:00 amCLT - GCM
1 stop6h 45mSpirit Airlines
Thu 12/252:40 pmGCM - CLT
1 stop8h 49mSpirit Airlines
Deal found 11/3$411
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:59 pmCLT - GCM
1 stop19h 46mMultiple Airlines
Tue 12/911:30 amGCM - CLT
2 stops24h 34mMultiple Airlines
Deal found 11/3$432
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:00 amCLT - GCM
1 stop6h 45mSpirit Airlines
Thu 1/12:40 pmGCM - CLT
1 stop5h 53mSpirit Airlines
Deal found 11/3$455
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:09 amCLT - GCM
Nonstop2h 56mAmerican Airlines
Tue 12/912:50 pmGCM - CLT
Nonstop3h 01mAmerican Airlines
Deal found 11/3$458
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:06 pmCHS - GCM
1 stop18h 43mAmerican Airlines
Sat 12/2712:50 pmGCM - CHS
1 stop19h 57mAmerican Airlines
Deal found 11/3$487
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:40 amGSP - GCM
1 stop6h 55mUnited Airlines
Thu 12/252:25 pmGCM - GSP
1 stop9h 31mUnited Airlines
Deal found 11/2$556
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:45 amSAV - GCM
1 stop7h 29mAmerican Airlines
Thu 11/279:00 amGCM - SAV
1 stop6h 50mAmerican Airlines
Deal found 11/2$610
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:00 amGSP - GCM
1 stop4h 57mAmerican Airlines
Thu 12/251:03 pmGCM - GSP
2 stops19h 33mAmerican Airlines
Deal found 11/2$674

Cheap flight deals from South Carolina to Grand Cayman

Keep the following information in mind while searching for South Carolina to Grand Cayman flight deals. Data was last updated November 3, 2025.

Round-trip from

$313
(American Airlines)

One-way from

$102
(Priceline)
From South Carolina to Grand Cayman
Search Deals
One-way flight from South Carolina to Grand Cayman
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from South Carolina to Grand Cayman that are best for you.

Fly from

South Carolina

Fly to

Grand Cayman

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 2/21

5:45 am-1:40 pm

1 stop7h 55m

George Town Owen Roberts Intl

Sat 2/28

2:35 pm-12:59 am

1 stop10h 24m

$307

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 11/15

7:00 am-3:25 pm

1 stop8h 25m

George Town Owen Roberts Intl

Sat 11/22

12:39 pm-9:24 pm

1 stop8h 45m

$313

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 12/10

8:10 pm-1:45 pm

2 stops17h 35m

George Town Owen Roberts Intl

Sun 12/14

2:40 pm-11:59 pm

1 stop9h 19m

$351

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Tue 3/10

5:31 am-11:15 am

1 stop6h 44m

George Town Owen Roberts Intl

Wed 3/11

1:15 pm-11:20 pm

1 stop9h 05m

$400

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 2/25

10:11 pm-1:40 pm

2 stops15h 29m

George Town Owen Roberts Intl

Sun 3/1

2:35 pm-12:59 am

1 stop10h 24m

$400

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 12/3

5:59 pm-1:45 pm

1 stop19h 46m

George Town Owen Roberts Intl

Wed 12/10

11:30 am-8:22 am

2 stops20h 52m

$419

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 12/3

5:59 pm-1:45 pm

1 stop19h 46m

George Town Owen Roberts Intl

Tue 12/9

11:30 am-12:04 pm

2 stops24h 34m

$432

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 4/18

8:44 pm-12:45 pm

2 stops17h 01m

George Town Owen Roberts Intl

Sat 4/25

3:15 pm-10:17 am

1 stop18h 02m

$439

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 12/3

9:09 am-12:05 pm

Nonstop2h 56m

George Town Owen Roberts Intl

Wed 12/10

3:45 pm-10:57 pm

1 stop7h 12m

$468

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Tue 12/16

6:33 am-12:40 pm

1 stop6h 07m

George Town Owen Roberts Intl

Tue 12/23

1:52 pm-10:11 pm

1 stop8h 19m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 31 results
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Best time to book a flight from South Carolina to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Grand Cayman

What is the cheapest month to book a flight from South Carolina to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $355). Flying from South Carolina to Grand Cayman in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Grand Cayman?

    Airlines like Spirit Airlines, American Airlines, and Delta fly from South Carolina to Grand Cayman in about 5h 46m. The time it takes to get you to your destination can typically vary by up to 2h 39m. South Carolina and Grand Cayman are separated by a distance of 1079 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Carolina to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on South Carolina to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Grand Cayman.

  • Can I find deals for business class flights from South Carolina to Grand Cayman?

    Yes. Cheapflights offers flight deals from South Carolina to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $355). Flying from South Carolina to Grand Cayman in February is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Grand Cayman

Discover the top 2 airlines that operate flights from South Carolina to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$600FlexibilityNo cancel feeOn-time71%
DeltaCheapest$555Average$685FlexibilityNo cancel feeOn-timeN/A

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