HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Grand Cayman

$181+ Cheap flights from South Carolina to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Grand Cayman with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Grand Cayman

Keep the following information in mind while searching for South Carolina to Grand Cayman flight deals. Data was last updated May 1, 2025.

Round-trip from

$470
(Kiwi.com)

One-way from

$181
(Kiwi.com)
From South Carolina to Grand Cayman
Search Deals
One-way flight from South Carolina to Grand Cayman
Search Deals

Find flight deals from South Carolina to Grand Cayman

Cheapest flights from South Carolina to Grand Cayman
Explore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/149:32 pmCLT - GCM
1 stop15h 08mMultiple Airlines
Wed 6/1811:30 amGCM - CLT
1 stop19h 39mMultiple Airlines
Deal found 4/30$470
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/158:47 pmCHS - GCM
1 stop15h 13mAmerican Airlines
Sat 11/226:10 pmGCM - CHS
1 stop6h 06mAmerican Airlines
Deal found 4/30$484
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/97:16 pmGSP - GCM
2 stops16h 54mAmerican Airlines
Sat 8/1612:10 pmGCM - GSP
2 stops10h 47mAmerican Airlines
Deal found 4/29$499
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/49:00 amCLT - GCM
Nonstop3h 00mAmerican Airlines
Tue 11/116:10 pmGCM - CLT
Nonstop3h 00mAmerican Airlines
Deal found 4/30$525
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/227:35 amGSP - GCM
1 stop4h 45mDelta
Thu 5/2912:35 pmGCM - GSP
1 stop6h 40mDelta
Deal found 4/30$532
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:30 amCLT - GCM
1 stop7h 07mDelta
Tue 12/92:02 pmGCM - CLT
1 stop7h 00mDelta
Deal found 4/30$540
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/295:23 amSAV - GCM
1 stop7h 02mDelta
Sat 8/21:10 pmGCM - SAV
1 stop8h 50mDelta
Deal found 4/30$548
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:40 amCAE - GCM
1 stop6h 51mDelta
Mon 9/2212:53 pmGCM - CAE
1 stop7h 55mDelta
Deal found 4/30$615
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/305:57 pmCAE - GCM
2 stops18h 13mAmerican Airlines
Sat 9/612:45 pmGCM - CAE
1 stop10h 19mAmerican Airlines
Deal found 4/30$639
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/298:13 pmSAV - GCM
2 stops17h 57mAmerican Airlines
Sat 8/23:05 pmGCM - SAV
1 stop6h 31mAmerican Airlines
Deal found 4/30$639
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/173:41 pmSAV - GCM
1 stop21h 49mUnited Airlines
Sat 6/212:40 pmGCM - SAV
1 stop8h 19mUnited Airlines
Deal found 4/30$650
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:30 amCLT - GCM
1 stop9h 55mUnited Airlines
Mon 12/15:35 pmGCM - CLT
1 stop28h 17mUnited Airlines
Deal found 4/29$808

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from South Carolina to Grand Cayman that are best for you.

Fly from

South Carolina

Fly to

Grand Cayman

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 6/14

9:32 pm-11:40 am

1 stop15h 08m

George Town Owen Roberts Intl

Wed 6/18

11:30 am-8:09 am

1 stop19h 39m

$470

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Sat 8/9

7:16 pm-11:10 am

2 stops16h 54m

George Town Owen Roberts Intl

Sat 8/16

12:10 pm-11:57 pm

2 stops10h 47m

$499

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/22

7:35 am-11:20 am

1 stop4h 45m

George Town Owen Roberts Intl

Thu 5/29

12:35 pm-8:15 pm

1 stop6h 40m

$532

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 7/29

5:23 am-11:25 am

1 stop7h 02m

George Town Owen Roberts Intl

Sat 8/2

1:10 pm-11:00 pm

1 stop8h 50m

$548

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 8/9

10:25 pm-11:10 am

1 stop13h 45m

George Town Owen Roberts Intl

Sat 8/16

3:05 pm-7:10 pm

Nonstop3h 05m

$555

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Thu 9/18

5:40 am-11:31 am

1 stop6h 51m

George Town Owen Roberts Intl

Mon 9/22

12:53 pm-9:48 pm

1 stop7h 55m

$615

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Sat 8/30

5:57 pm-11:10 am

2 stops18h 13m

George Town Owen Roberts Intl

Sat 9/6

12:45 pm-12:04 am

1 stop10h 19m

$639

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 7/29

8:13 pm-1:10 pm

2 stops17h 57m

George Town Owen Roberts Intl

Sat 8/2

3:05 pm-10:36 pm

1 stop6h 31m

$639

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 6/17

3:41 pm-12:30 pm

1 stop21h 49m

George Town Owen Roberts Intl

Sat 6/21

2:40 pm-11:59 pm

1 stop8h 19m

$650

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 5/11

5:40 am-11:20 am

1 stop6h 40m

George Town Owen Roberts Intl

Mon 5/19

12:35 pm-8:16 pm

1 stop6h 41m

$900

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/1

Showing 1-10 of 19 results
1
2

Best time to book a flight from South Carolina to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Grand Cayman

What is the cheapest month to book a flight from South Carolina to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated May 1, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and American Airlines from South Carolina to Grand Cayman by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
WestJet
7.2
Good
2,826 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air Canada
7.0
Good
9,245 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Grand Cayman one-way?

    The cheapest airline one-way is Air Canada, with whom users have recently found tickets for as low as $218. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from South Carolina to Grand Cayman for a low price.

  • Can I find deals for flights from South Carolina to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on South Carolina to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Grand Cayman.

  • Can I find deals for business class flights from South Carolina to Grand Cayman?

    Yes. Cheapflights offers flight deals from South Carolina to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to George Town flights
LaGuardia to George Town flights
Newark to George Town flights
Miami to George Town flights
Hobby to George Town flights
Baltimore to George Town flights
Dulles Intl to George Town flights
Philadelphia to George Town flights
Dallas/Fort Worth to George Town flights
Reagan-National to George Town flights
George Bush Intcntl to George Town flights
O'Hare Intl to George Town flights
Boston to George Town flights
Atlanta to George Town flights
Los Angeles to George Town flights
Orlando to George Town flights
Fort Lauderdale to George Town flights
Denver to George Town flights
Cincinnati to George Town flights
Charlotte to George Town flights
Tampa to George Town flights
Seattle to George Town flights
Omaha to George Town flights
West Palm Beach to George Town flights
Kansas City to George Town flights
Austin to George Town flights
Columbus to George Town flights
Raleigh to George Town flights
Minneapolis to George Town flights
Sky Harbor Intl to George Town flights
Indianapolis to George Town flights
Midway to George Town flights
Love Field to George Town flights
Ontario to George Town flights
Albany to George Town flights
San Francisco to George Town flights
Nashville to George Town flights
Cleveland to George Town flights
Detroit to George Town flights
White Plains to George Town flights
Pittsburgh to George Town flights
Milwaukee to George Town flights
Des Moines to George Town flights
New Orleans to George Town flights
St. Louis to George Town flights
Jacksonville to George Town flights
Las Vegas to George Town flights
Harrisburg to George Town flights
Grand Rapids to George Town flights
San Antonio to George Town flights

Top 2 airlines flying from South Carolina to Grand Cayman

Discover the top 2 airlines that operate flights from South Carolina to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$579FlexibilityNo cancel feeOn-time71%
DeltaCheapest$460Average$627FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.