$313+ Cheap flights from South Carolina to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Jun 21 — Jun 281
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Grand Cayman
Keep the following information in mind while searching for South Carolina to Grand Cayman flight deals. Data was last updated June 16, 2025.
Round-trip from | $484 (Kiwi.com) |
|---|---|
One-way from | $313 (American Airlines) |
Find flight deals from South Carolina to Grand Cayman
Cheapest flights from South Carolina to Grand CaymanExplore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.
Explore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/103:28 pmCLT - GCM
1 stop6h 52mMultiple Airlines
Thu 7/174:45 pmGCM - CLT
1 stop20h 50mMultiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/158:47 pmCHS - GCM
1 stop15h 13mAmerican Airlines
Sat 11/222:20 pmGCM - CHS
1 stop4h 52mAmerican Airlines
Deal found 6/15![American Airlines logo]()
$497
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/86:29 amGSP - GCM
1 stop5h 41mAmerican Airlines
Sat 7/123:30 pmGCM - GSP
1 stop7h 49mAmerican Airlines
Deal found 6/15![American Airlines logo]()
$519
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/308:05 amCAE - GCM
1 stop4h 32mDelta
Fri 9/512:50 pmGCM - CAE
1 stop5h 23mDelta
Deal found 6/15![Delta logo]()
$540
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/205:23 amSAV - GCM
1 stop6h 59mDelta
Wed 7/2312:37 pmGCM - SAV
1 stop7h 26mDelta
Deal found 6/14![Delta logo]()
$550
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/249:30 amCLT - GCM
Nonstop2h 55mAmerican Airlines
Mon 9/2912:25 pmGCM - CLT
Nonstop3h 12mAmerican Airlines
Deal found 6/16![American Airlines logo]()
$560
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/297:00 amCLT - GCM
1 stop6h 30mUnited Airlines
Tue 8/51:35 pmGCM - CLT
1 stop7h 22mUnited Airlines
Deal found 6/14![United Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/304:21 pmCAE - GCM
2 stops19h 49mAmerican Airlines
Fri 9/512:10 pmGCM - CAE
2 stops10h 33mAmerican Airlines
Deal found 6/15![American Airlines logo]()
$644
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/75:36 amCLT - GCM
1 stop6h 46mDelta
Sun 8/1012:37 pmGCM - CLT
1 stop9h 15mDelta
Deal found 6/14![Delta logo]()
$650
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/208:33 pmSAV - GCM
2 stops15h 37mAmerican Airlines
Wed 7/2312:10 pmGCM - SAV
2 stops9h 26mAmerican Airlines
Deal found 6/14![American Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1511:25 amCHS - GCM
2 stops29h 00mUnited Airlines
Sat 11/222:40 pmGCM - CHS
2 stops24h 29mUnited Airlines
Deal found 6/16![United Airlines logo]()
$794
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/179:10 amSAV - GCM
1 stop28h 20mUnited Airlines
Sat 6/212:40 pmGCM - SAV
1 stop8h 19mUnited Airlines
Deal found 6/16![United Airlines logo]()
$901
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
Use the filters below to find and compare flights from South Carolina to Grand Cayman that are best for you.
Fly from
South Carolina
Fly to
Grand Cayman
Route
Depart
Return
Price
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Thu 7/10
3:28 pm-9:20 pm
1 stop6h 52m
George Town Owen Roberts Intl
Thu 7/17
4:45 pm-2:35 pm
1 stop20h 50m
$484
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Sat 11/15
8:47 pm-12:00 pm
1 stop15h 13m
George Town Owen Roberts Intl
Sat 11/22
2:20 pm-7:12 pm
1 stop4h 52m
$497
GreenvilleGeorge Town
GSP - GCM
GSPGCM
Greenville
Tue 7/8
6:29 am-11:10 am
1 stop5h 41m
George Town Owen Roberts Intl
Sat 7/12
3:30 pm-12:19 am
1 stop7h 49m
$519
ColumbiaGeorge Town
CAE - GCM
CAEGCM
Columbia Metropolitan
Sat 8/30
8:05 am-11:37 am
1 stop4h 32m
George Town Owen Roberts Intl
Fri 9/5
12:50 pm-7:13 pm
1 stop5h 23m
$540
SavannahGeorge Town
SAV - GCM
SAVGCM
Savannah/Hilton Head
Sun 7/20
5:23 am-11:22 am
1 stop6h 59m
George Town Owen Roberts Intl
Wed 7/23
12:37 pm-9:03 pm
1 stop7h 26m
$550
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Wed 9/24
9:30 am-11:25 am
Nonstop2h 55m
George Town Owen Roberts Intl
Mon 9/29
12:25 pm-4:37 pm
Nonstop3h 12m
$560
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Tue 7/29
7:00 am-12:30 pm
1 stop6h 30m
George Town Owen Roberts Intl
Tue 8/5
1:35 pm-9:57 pm
1 stop7h 22m
$625
ColumbiaGeorge Town
CAE - GCM
CAEGCM
Columbia Metropolitan
Sat 8/30
4:21 pm-11:10 am
2 stops19h 49m
George Town Owen Roberts Intl
Fri 9/5
12:10 pm-11:43 pm
2 stops10h 33m
$644
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Thu 8/7
5:36 am-11:22 am
1 stop6h 46m
George Town Owen Roberts Intl
Sun 8/10
12:37 pm-10:52 pm
1 stop9h 15m
$650
SavannahGeorge Town
SAV - GCM
SAVGCM
Savannah/Hilton Head
Sun 7/20
8:33 pm-11:10 am
2 stops15h 37m
George Town Owen Roberts Intl
Wed 7/23
12:10 pm-10:36 pm
2 stops9h 26m
$694
Showing 1-10 of 19 results
Best time to book a flight from South Carolina to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Grand Cayman
What is the cheapest month to book a flight from South Carolina to Grand Cayman?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated June 16, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and American Airlines from South Carolina to Grand Cayman by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Food
7.3
Crew
8.5
Entertainment
7.9
Overall
8.0
Boarding
8.2
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Comfort
7.9
Food
7.3
Crew
8.5
Entertainment
7.9
Overall
8.0
Boarding
8.2
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Comfort
7.9
Food
7.3
Crew
8.5
Entertainment
7.9
Overall
8.0
Boarding
8.2
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Comfort
7.9
Food
7.3
Crew
8.5
Entertainment
7.9
Overall
8.0
Boarding
8.2
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Comfort
7.9
Food
7.3
Crew
8.5
Entertainment
7.9
Overall
8.0
Boarding
8.2
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Comfort
7.9
Food
7.3
Crew
8.5
Entertainment
7.9
Overall
8.0
Boarding
8.2
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Grand Cayman
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from South Carolina to Grand Cayman
Discover the top 2 airlines that operate flights from South Carolina to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$414 | Average$603 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$460 | Average$627 | FlexibilityNo cancel fee | On-timeN/A |