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Grand Cayman

$165+ Cheap flights from South Carolina to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Aug 7 — Aug 141
Thu 8/7
Thu 8/14
1 adult, Economy
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Cheap flight deals from South Carolina to Grand Cayman

Keep the following information in mind while searching for South Carolina to Grand Cayman flight deals. Data was last updated August 2, 2025.

Round-trip from

$466
(Kiwi.com)

One-way from

$165
(Trip.com)
From South Carolina to Grand Cayman
Search Deals
One-way flight from South Carolina to Grand Cayman
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Find flight deals from South Carolina to Grand Cayman

Cheapest flights from South Carolina to Grand Cayman
Explore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/131:50 pmCLT - GCM
1 stop22h 50mMultiple Airlines
Sat 9/2011:25 amGCM - CLT
1 stop7h 50mMultiple Airlines
Deal found 8/1$466
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/148:02 amCHS - GCM
1 stop4h 34mDelta
Sun 9/2112:52 pmGCM - CHS
1 stop8h 41mDelta
Deal found 7/31$497
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/65:26 pmCHS - GCM
2 stops18h 44mAmerican Airlines
Sat 9/1312:25 pmGCM - CHS
1 stop7h 40mAmerican Airlines
Deal found 7/31$501
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:24 pmGSP - GCM
1 stop18h 01mAmerican Airlines
Sat 10/258:25 amGCM - GSP
1 stop6h 33mAmerican Airlines
Deal found 8/1$525
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:30 amCLT - GCM
1 stop7h 07mDelta
Thu 1/152:00 pmGCM - CLT
1 stop9h 54mDelta
Deal found 8/1$550
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/259:30 pmCLT - GCM
1 stop14h 40mAmerican Airlines
Wed 10/2912:25 pmGCM - CLT
Nonstop3h 00mAmerican Airlines
Deal found 7/31$565
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:50 amSAV - GCM
1 stop5h 41mDelta
Sat 9/612:52 pmGCM - SAV
1 stop7h 37mDelta
Deal found 7/31$575
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/67:03 pmSAV - GCM
2 stops17h 07mAmerican Airlines
Sat 9/1312:25 pmGCM - SAV
1 stop5h 53mAmerican Airlines
Deal found 8/1$579
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:46 pmCAE - GCM
1 stop15h 19mAmerican Airlines
Fri 12/125:35 pmGCM - CAE
1 stop5h 58mAmerican Airlines
Deal found 7/30$590
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1412:08 pmCHS - GCM
3 stops24h 32mMultiple Airlines
Sun 9/2112:40 pmGCM - CHS
2 stops19h 25mMultiple Airlines
Deal found 7/31$601
This Priceline deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:30 amCLT - GCM
1 stop28h 25mAir Canada
Sun 10/2612:30 pmGCM - CLT
1 stop26h 47mAir Canada
Deal found 8/1$607
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/63:15 pmSAV - GCM
3 stops31h 05mMultiple Airlines
Sat 9/131:45 pmGCM - SAV
2 stops20h 20mMultiple Airlines
Deal found 7/31$735

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from South Carolina to Grand Cayman that are best for you.

Fly from

South Carolina

Fly to

Grand Cayman

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sat 9/13

1:50 pm-11:40 am

1 stop22h 50m

George Town Owen Roberts Intl

Sat 9/20

11:25 am-8:15 pm

1 stop7h 50m

$466

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sun 9/14

8:02 am-11:36 am

1 stop4h 34m

George Town Owen Roberts Intl

Sun 9/21

12:52 pm-10:33 pm

1 stop8h 41m

$497

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 9/6

5:26 pm-11:10 am

2 stops18h 44m

George Town Owen Roberts Intl

Sat 9/13

12:25 pm-9:05 pm

1 stop7h 40m

$501

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Sat 10/18

6:24 pm-11:25 am

1 stop18h 01m

George Town Owen Roberts Intl

Sat 10/25

8:25 am-3:58 pm

1 stop6h 33m

$525

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Mon 12/15

5:30 am-12:37 pm

1 stop7h 07m

George Town Owen Roberts Intl

Thu 1/15

2:00 pm-11:54 pm

1 stop9h 54m

$550

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Tue 1/27

9:00 am-12:00 pm

Nonstop3h 00m

George Town Owen Roberts Intl

Sat 1/31

1:40 pm-4:45 pm

Nonstop3h 05m

$560

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Mon 9/1

6:50 am-11:31 am

1 stop5h 41m

George Town Owen Roberts Intl

Sat 9/6

12:52 pm-9:29 pm

1 stop7h 37m

$575

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Sat 9/6

7:03 pm-11:10 am

2 stops17h 07m

George Town Owen Roberts Intl

Sat 9/13

12:25 pm-7:18 pm

1 stop5h 53m

$579

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Mon 12/8

8:46 pm-12:05 pm

1 stop15h 19m

George Town Owen Roberts Intl

Fri 12/12

5:35 pm-11:33 pm

1 stop5h 58m

$590

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sun 9/14

12:08 pm-11:40 am

3 stops24h 32m

George Town Owen Roberts Intl

Sun 9/21

12:40 pm-9:05 am

2 stops19h 25m

$601

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 18 results
1
2

Best time to book a flight from South Carolina to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Grand Cayman

What is the cheapest month to book a flight from South Carolina to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated August 2, 2025.
Read through reviews of airlines operating flights from South Carolina to Grand Cayman, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,983 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Air Canada
7.1
Good
9,855 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Grand Cayman one-way?

    The cheapest airline one-way is Air Canada, with whom users have recently found tickets for as low as $181. However, be on the lookout for offers from Southwest and American Airlines, as they are both options that can get you from South Carolina to Grand Cayman for a low price.

  • Can I find deals for flights from South Carolina to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on South Carolina to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Grand Cayman.

  • Can I find deals for business class flights from South Carolina to Grand Cayman?

    Yes. Cheapflights offers flight deals from South Carolina to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Grand Cayman

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Top 2 airlines flying from South Carolina to Grand Cayman

Discover the top 2 airlines that operate flights from South Carolina to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$605FlexibilityNo cancel feeOn-time71%
DeltaCheapest$460Average$627FlexibilityNo cancel feeOn-timeN/A

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